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Your search keyword '"Meshal S. Alotaibi"' showing total 3 results
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3 results on '"Meshal S. Alotaibi"'

1. The effect of oseltamivir use in critically ill patients with COVID-19: A multicenter propensity score-matched study

Author

Ohoud Aljuhani, Ghazwa B. Korayem, Ali F. Altebainawi, Meshal S. Alotaibi, Noura A. Alrakban, Ragia H. Ghoneim, Ramesh Vishwakarma, Abdulrahman I. Al Shaya, Shmeylan Al Harbi, Jawaher Gramish, Dahlia M. Almutairi, Ghada Alqannam, Faisal F. Alamri, Abdullah F. Alharthi, Mashael Alfaifi, Abdullah Al Amer, Abeer A. Alenazi, Norah Bin Aydan, Mai Alalawi, and Khalid Al Sulaiman

Subjects
COVID-19, Viral clearance, Oseltamivir, Critically ill, Intensive care unit, Mechanical ventilation duration, Therapeutics. Pharmacology, RM1-950
Abstract

Background: Oseltamivir has been used as adjunctive therapy in the management of patients with COVID-19. However, the evidence about using oseltamivir in critically ill patients with severe COVID-19 remains scarce. This study aims to evaluate the effectiveness and safety of oseltamivir in critically ill patients with COVID-19. Methods: This multicenter, retrospective cohort study includes critically ill adult patients with COVID-19 admitted to the intensive care unit (ICU). Patients were categorized into two groups based on oseltamivir use within 48 hours of ICU admission (Oseltamivir vs. Control). The primary endpoint was viral load clearance. Results: A total of 226 patients were matched into two groups based on their propensity score. The time to COVID-19 viral load clearance was shorter in patients who received oseltamivir (11 vs. 16 days, p = 0.042; beta coefficient: −0.84, 95%CI: (−1.33, 0.34), p = 0.0009). Mechanical ventilation (MV) duration was also shorter in patients who received oseltamivir (6.5 vs. 8.5 days, p = 0.02; beta coefficient: −0.27, 95% CI: [−0.55,0.02], P = 0.06). In addition, patients who received oseltamivir had lower odds of hospital/ventilator-acquired pneumonia (OR:0.49, 95% CI:(0.283,0.861), p = 0.01). On the other hand, there were no significant differences between the groups in the 30-day and in-hospital mortality. Conclusion: Oseltamivir was associated with faster viral clearance and shorter MV duration without safety concerns in critically ill COVID-19 patients.

Published
2023
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2. Cellulitis Left Lower Leg Secondary to Pseudomonas aeruginosa Bacteremia: A Case Report

Author

Meshal S. Alotaibi, Ehab M. Abdo, Alaa Sedik, Mahmood A. Makhdoomi, Syed O. Ilyas, and Ashraf A. Elsayed

Subjects
medicine.medical_specialty, business.industry, Pseudomonas aeruginosa, Transmission (medicine), Acute infection, Thigh, medicine.disease_cause, medicine.disease, Dermatology, Vaseline, medicine.anatomical_structure, Pseudomonas infection, Bacteremia, Cellulitis, Medicine, business
Abstract

Cellulitis is a non-necrotizing inflammation of the skin and subcutaneous tissues that usually results from an acute infection. The gram-negative bacillus Pseudomonas aeruginosa causes a wide range of clinical illnesses. It is, however, most commonly linked to a hospital-acquired illness. We describe a case report of a 45-year-old Saudi man who developed vesiculous bullae, scaling, and sloughing of the overlying skin after initially experiencing redness and heat in the mid-right lower thigh. Though it was not a common suspect bacteria, Pseudomonas aeruginosa was detected from the case. It's possible that it's the result of a community-acquired infection.Patient was treated conservatively with intravenous antibiotics and local hygiene treatments such as Vaseline (bactigrass) dressing and topical antibiotics.Patient improved and discharged with complete resolution of cellulitis. Objectives: Describe the pathophysiology of community-acquired infections. Review the laboratory tests used in the evaluation of community-acquired infections. Summarize the management of community-acquired infections. Outline the importance of improving care coordination among the interprofessional team to prevent transmission of infections and enhance the delivery of care for patients affected by community-acquired infections.

Published
2021

3. Cellulitis left lower leg secondary to Pseudomonas aeruginosa bacteremia: case of community -acquired infection

Author

Meshal S. Alotaibi, Syed O. Ilyas, Mahmood A. Makhdoomi, Ehab M. Abdo, Alaa Sedik, and Ashraf A. Elsayed

Subjects
business.industry, Pseudomonas aeruginosa, Cellulitis, Bacteremia, Medicine, business, medicine.disease_cause, medicine.disease, Microbiology
Abstract

The term cellulitis is commonly used to indicate a nonnecrotizing inflammation of the skin and subcutaneous tissues, usually from acute infection. Pseudomonas aeruginosa is a gram-negative bacillus that causes wide spectrum clinical infections. However, it is most frequently associated with hospital-acquired infection. Authors are presenting a case report of 45 years old Saudi male who presented initially with redness and hotness in the mid of right lower leg gradually increased with development of vesiculous bullae, scaling and sloughing of overlying skin. Pseudomonas aeruginosa was identified from the case, though it was not a usual suspected organism. It might be due to community-acquired infection. Patient was treated conservatively with I/V antibiotic and local hygienic methods including dressing with vaseline (bactigrass) and topical antibiotics. Patient improved and discharged with complete resolution of cellulitis

Published
2019

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