1,615 results on '"Merghoub, Taha'
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2. Synthetic dual co-stimulation increases the potency of HIT and TCR-targeted cell therapies
3. FLT1 activation in cancer cells promotes PARP-inhibitor resistance in breast cancer
4. Multiplexed Serial Imaging of Immunotherapy Response with Serrs Nanoprobes.
5. Pharmacologic LDH inhibition redirects intratumoral glucose uptake and improves antitumor immunity in solid tumor models
6. TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models
7. Concurrent SOS1 and MEK suppression inhibits signaling and growth of NF1-null melanoma
8. TYRP1 directed CAR T cells control tumor progression in preclinical melanoma models
9. Comparative study of immune response to local tumor destruction modalities in a murine breast cancer model
10. Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer
11. Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
12. Molecular Heterogeneity and Immune Infiltration Drive Clinical Outcomes in Upper Tract Urothelial Carcinoma
13. Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer
14. Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer
15. Immunotherapy-Mediated Thyroid Dysfunction: Genetic Risk and Impact on Outcomes with PD-1 Blockade in Non–Small Cell Lung Cancer
16. 789 Immune checkpoint blockade augments cyclophosphamide induced anti-tumor immunity by expanding effector CD8+ T cell clones in a preclinical melanoma model
17. 878 T cell immunotherapies recruit and activate neutrophils to eliminate tumor antigen escape variants
18. 968 PD-1hiFoxp3-CD4+ tumor-infiltrating T-cell lineage commitment impacts the immunotherapy outcome
19. 525 Investigating dynamic IDO-Kyn-AhR pathway-induced tumor immunosuppression using imaging modality to optimize AhR therapeutic intervention
20. 1444 Pharmacologic LDH inhibition redirects intratumoral glucose consumption and improves response to CTLA-4 blockade
21. MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma
22. Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
23. Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade
24. T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants
25. The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer
26. Heat-inactivated modified vaccinia virus Ankara boosts Th1 cellular and humoral immunity as a vaccine adjuvant
27. In vivo tumor immune microenvironment phenotypes correlate with inflammation and vasculature to predict immunotherapy response
28. A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
29. Neoantigen quality predicts immunoediting in survivors of pancreatic cancer
30. Fundamental immune–oncogenicity trade-offs define driver mutation fitness
31. Anatomic position determines oncogenic specificity in melanoma
32. Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma
33. Brain radiotherapy, tremelimumab-mediated CTLA-4-directed blockade +/− trastuzumab in patients with breast cancer brain metastases
34. Plasma secretome analyses identify IL-8 and nitrites as predictors of poor prognosis in nasopharyngeal carcinoma patients
35. Enhancing immunotherapy in cancer by targeting emerging immunomodulatory pathways
36. Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma
37. Heat-inactivated modified vaccinia virus Ankara boosts Th1 cellular and humoral immunity as a vaccine adjuvant
38. In vivo tumor immune microenvironment phenotypes correlate with inflammation and vasculature to predict immunotherapy response
39. Brain radiotherapy, tremelimumab-mediated CTLA-4-directed blockade +/− trastuzumab in patients with breast cancer brain metastases
40. TAD hierarchy restricts poised LTR activation and loss of TAD hierarchy promotes LTR co-option in cancer
41. Immunologic Profiling of Immune-Related Cutaneous Adverse Events with Checkpoint Inhibitors Reveals Polarized Actionable Pathways
42. Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of cancer
43. In vivo optical imaging-guided targeted sampling for precise diagnosis and molecular pathology
44. Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
45. Uptake of oxidized lipids by the scavenger receptor CD36 promotes lipid peroxidation and dysfunction in CD8+ T cells in tumors
46. Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity
47. Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers
48. Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma
49. Immunologic Profiling of Immune-Related Cutaneous Adverse Events with Checkpoint Inhibitors Reveals Polarized Actionable Pathways
50. Increased p53 expression induced by APR-246 reprograms tumor-associated macrophages to augment immune checkpoint blockade
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