120 results on '"Meredith, Erik"'
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2. Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors
3. Chapter 2 Synthesis of geldanamycin using glycolate aldol reactions
4. Structure based design of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors from a phenotypic screen
5. Scaffold Morphing Identifies 3-Pyridyl Azetidine Ureas as Inhibitors of Nicotinamide Phosphoribosyltransferase (NAMPT)
6. Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells
7. Full-length myocilin protein is purified from mammalian cells as a dimer
8. Nicotinamide Phosphoribosyltransferase Inhibitor as a Novel Payload for Antibody–Drug Conjugates
9. The Discovery of (S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma
10. The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration
11. Total synthesis of (+)-geldanamycin and (-)-o-quinogeldanamycin: asymmetric glycolate aldol reactions and biological evaluation
12. The Discovery of N-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)-5-((6- ((methylamino)methyl)pyrimidin-4-yl)oxy)-1H-indole-1-carboxamide (Acrizanib), a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration
13. Identification of Orally Available Naphthyridine Protein Kinase D Inhibitors
14. Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D
15. Core Replacements in a Potent Series of VEGFR-2 Inhibitors and Their Impact on Potency, Solubility, and hERG
16. Discovery of Oral VEGFR-2 Inhibitors with Prolonged Ocular Retention That Are Efficacious in Models of Wet Age-Related Macular Degeneration
17. 3,5-Diarylazoles as novel and selective inhibitors of protein kinase D
18. The discovery of potent inhibitors of aldosterone synthase that exhibit selectivity over 11-β-hydroxylase
19. A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase
20. Lack of Involvement of CEP Adducts in TLR Activation and in Angiogenesis
21. Reliability of the Mouse Model of Choroidal Neovascularization Induced by Laser Photocoagulation
22. Design and synthesis of potent sensitizers of gram-negative bacteria based on a cholic acid scaffolding
23. Discovery and in Vivo Evaluation of Potent Dual CYP11B2 (Aldosterone Synthase) and CYP11B1 Inhibitors
24. ChemInform Abstract: A Reliable Synthesis of 3-Amino-5-alkyl and 5-Amino-3-alkyl Isoxazoles.
25. A Reliable Synthesis of 3-Amino-5-Alkyl and 5-Amino-3-Alkyl Isoxazoles
26. ChemInform Abstract: Syntheses of 1-Substituted-3-aminopyrazoles.
27. Syntheses of 1-substituted-3-aminopyrazoles
28. Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D
29. Identification of Orally Available Naphthyridine Protein Kinase D Inhibitors
30. ChemInform Abstract: Synthesis of the Left-Hand Portion of Geldanamycin Using an anti Glycolate Aldol Reaction.
31. A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase
32. Total Synthesis of (+)-Geldanamycin (I) and (-)-o-Quinogeldanamycin (II): Asymmetric Glycolate Aldol Reactions and Biological Evaluation.
33. Total Synthesis of (+)-Geldanamycin and (−)-o-Quinogeldanamycin: Asymmetric Glycolate Aldol Reactions and Biological Evaluation
34. Synthesis of Resveratrol Using a Direct Decarbonylative Heck Approach from Resorcylic Acid.
35. Selective Synthesis of the para-Quinone Region of Geldanamycin
36. Total Synthesis of (+)-Geldanamycin and (−)-o-Quinogeldanamycin with Use of Asymmetric Anti- and Syn-Glycolate Aldol Reactions
37. ChemInform Abstract: Glycolate Aldol Reactions with Boron Enolates of Bis‐4‐methoxyphenyl Dioxanone.
38. Glycolate aldol reactions with boron enolates of bis-4-methoxyphenyl dioxanone
39. ChemInform Abstract: Highly Selective syn Glycolate Aldol Reactions with Boron Enolates of Masamune Norephedrine Esters.
40. Highly selective syn glycolate aldol reactions with boron enolates of Masamune norephedrine esters
41. ChemInform Abstract: Anti‐Selective Glycolate Aldol Additions with an Oxapyrone Boron Enolate.
42. Synthesis of the Left-Hand Portion of Geldanamycin Using an Anti Glycolate Aldol Reaction
43. Anti-Selective Glycolate Aldol Additions with an Oxapyrone Boron Enolate
44. Synthesis of resveratrol using a direct decarbonylative Heck approach from resorcylic acid
45. Highly selective synglycolate aldol reactions with boron enolates of Masamune norephedrine esters
46. A Reliable Synthesis of 3-Amino-5-Alkyl and 5-Amino-3-Alkyl Isoxazoles.
47. ARYLPYRAZOLES AND ARYLISOXAZOLES AND THEIR USE AS PKD MODULATORS
48. CYCLOHEXEN-1-YL-PYRIDIN-2-YL-1H-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF AS SOLUBLE GUANYLATE CYCLASE ACTIVATORS
49. ChemInform Abstract: Synthesis of the Left-Hand Portion of Geldanamycin Using an anti Glycolate Aldol Reaction.
50. <atl>Glycolate aldol reactions with boron enolates of bis-4-methoxyphenyl dioxanone
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