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14 results on '"Merckle, Ludovic"'

5. Fibrosis mechanistic phenotyping and antifibrotic response determination with biomarkers in heart failure: one single biomarker may not fit all settings

Author

Girerd, Sophie, Frimat, Luc, Ducloux, Didier, Le Meur, Yannick, Mariat, Christophe, Moulin, Bruno, Mousson, Christiane, Rieu, Philippe, Dali-Youcef, Nassim, Merckle, Ludovic, Lepage, Xavier, Girerd, Nicolas, Jaisser, Frederic, Rossignol, Patrick, Ferreira, Joao Pedro, Zannad, Faiez, Centre d'investigation clinique [Nancy] (CIC), Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM), Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Cardiovascular and Renal Clinical Trialists [Vandoeuvre-les-Nancy] (INI-CRCT), Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy], IMPACT GEENAGE, ANR-15-IDEX-0004,LUE (ISITE),Lorraine Université d'Excellence(2016), ANR-15-RHUS-0004,FIGHT-HF,Combattre l'insuffisance cardiaque(2015), Service de Néphrologie [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service de Néphrologie et Urologie, Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon)-Hôpital Saint-Jacques, CHRU Brest - Service de Nephrologie (CHU - BREST - Nephrologie), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), CHU Saint-Etienne, Service de Néphrologie et Transplantation, CHU Strasbourg, Service de néphrologie (CHU de Dijon), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Centre Hospitalier Universitaire de Reims (CHU Reims), Laboratoire de Biochimie Générale et Spécialisée, Hôpitaux Universitaires de Strasbourg, Université de Lorraine (UL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Centre d'investigation clinique plurithématique Pierre Drouin (CIC-P), Centre de Recherche des Cordeliers (CRC), Université Paris Diderot - Paris 7 (UPD7)-École pratique des hautes études (EPHE)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), CIC-Nancy, Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy]-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de Cardiologie [CHRU Nancy], ANR-15-IDEX-04-LUE,LUE,Lorraine Université d'Excellence(2016), ANR: ANR-15-RHU-0004,Programme Investissement d'Avenir ANR-15-RHU-0004, DE CARVALHO, Philippe, ISITE - Isite LUE - - LUE2015 - ANR-15-IDEX-0004 - IDEX - VALID, Combattre l'insuffisance cardiaque - - FIGHT-HF2015 - ANR-15-RHUS-0004 - RHUS - VALID, and ANR-15-IDEX-0004,LUE,Isite LUE(2015)

Subjects
[SDV] Life Sciences [q-bio], [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, spironolactone, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [SDV]Life Sciences [q-bio], heart failure, myocardial fibrosis, ComputingMilieux_MISCELLANEOUS, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, [SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Abstract

International audience; Biomarker-based phenotyping of myocardial fibrosis identifies patients with heart failure with preserved ejection fraction resistant to the beneficial effects of spironolactone: results from the Aldo-DHF trial. [Eur J Heart Fail. 2018]

Published
2018
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6. Additional file 3: of EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) study: study protocol for a randomized controlled trial

Author

Girerd, Sophie, Frimat, Luc, Ducloux, Didier, Meur, Yannick Le, Mariat, Christophe, Moulin, Bruno, Mousson, Christiane, Rieu, Philippe, Dali-Youcef, Nassim, Merckle, Ludovic, Lepage, Xavier, Rossignol, Patrick, Girerd, Nicolas, and FrĂŠdĂŠric Jaisser

Abstract

Informed consent materials 2. (PDF 142 kb)

Published
2018
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7. Additional file 2: of EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) study: study protocol for a randomized controlled trial

Author

Girerd, Sophie, Frimat, Luc, Ducloux, Didier, Meur, Yannick Le, Mariat, Christophe, Moulin, Bruno, Mousson, Christiane, Rieu, Philippe, Dali-Youcef, Nassim, Merckle, Ludovic, Lepage, Xavier, Rossignol, Patrick, Girerd, Nicolas, and FrĂŠdĂŠric Jaisser

Abstract

Informed consent materials 1. (PDF 189 kb)

Published
2018
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8. Additional file 1: of EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) study: study protocol for a randomized controlled trial

Author

Girerd, Sophie, Frimat, Luc, Ducloux, Didier, Meur, Yannick Le, Mariat, Christophe, Moulin, Bruno, Mousson, Christiane, Rieu, Philippe, Dali-Youcef, Nassim, Merckle, Ludovic, Lepage, Xavier, Rossignol, Patrick, Girerd, Nicolas, and FrĂŠdĂŠric Jaisser

Abstract

SPIRIT 2013 checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 58 kb)

Published
2018
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12. Semisynthesis of D-Ring Modified Taxoids: Novel Thia Derivatives of Docetaxel.

Author

Merckle, Ludovic, Dubois, Joelle, Place, Estelle, Thoret, Sylviane, Gueritte, Francoise, Guenard, Daniel, Poupat, Christiane, Ahond, Alain, and Potier, Pierre

Subjects
*DOCETAXEL, *ANTINEOPLASTIC agents, *BIOSYNTHESIS
Abstract

Discusses the semisynthesis of novel thia derivatives of docetaxel, an anticancer drug of the taxoid series. Role of the oxetane ring; Formation of the thietane ring; Synthesis of 5(20)-thiadocetaxel and its 7-deoxy analogue.

Published
2001
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