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PRESCRIBING NOTES Contact the American Academy of Pediatrics, Centers for Disease Control and local health authorities for information on current immunization recommendations and guidelines, For information on Vaccine Adverse Event [...]

A 77-year-old glaucoma patient who once had intraocular pressure (IOP) of 25mm Hg in the right eye and 27mm Hg in the left while on daily Timoptic (timolol maleate 0.5%, [...]

Zocor, a product of Merck & Co., Inc., is used as a supplement to daily diet for patients suffering from high cholesterol, coronary heart disease (CHD), diabetes and vascular disease. The dosage and administration details are presented.

Key points * The limitations of cervical cytology in controlling cervical cancer are due to: (1) the absence of regular screening; (2) the poor reproducibility of cytologic diagnosis; and (3) [...]

In the ongoing war on cancer, the new human papillomavirus (HPV) vaccine has been hailed as a breakthrough. 'This is a watershed event,' proclaimed American Cancer Society president Carolyn Runowicz--an [...]

Vytorin (ezetimibe/ simvastatin), a product of Merck/ Schering-Plough Pharmaceuticals, helps in the absorption of cholesterol that comes from food and also reduces the cholesterol that the body makes naturally. The dosage and administration information about the drug is presented.

Merck and Company Inc's 'Proscar', a treatment for benign prostate enlargement, has been give FDA approval and will be available to the public in Jul 1992. Proscar is expected to generate $500,000 in sales in 1992 and could reach $1 billion annual sales by 1995. The drug, which will cost patients about $640 per year, is an alternative to prostate surgery, which costs $7,000-$8,000 and is not always successful. Merck retains exclusive patent rights on Proscar through 2007.

Raptiva 100 mg/ml powder and solvent for solution for injection (efalizumab) New information relating to infections and progressive multifocal leukoencephalopathy. Merck Serono, 0208 818 7373, medinfo.uk@merckserono.net Oily phenol injection BP [...]

Byline: Granell, Alison [ON OUR RADAR] Stranded with cancer Does your DNA say DOA? Mayo Clinic scientists found that young adults with colon cancer have shorter-than-normal telomeres, the caps that [...]

Pharmacology Update Raltegravir Tablets (Isentress™) By William T. Elliott, MD, FACP, and James Chan, PharmD, PhD. Dr. Elliott is Chair, Formulary Committee, Northern California Kaiser Permanente; Assistant Clinical Professor of [...]

What is next on the HPV vaccine horizon? As clinicians begin to integrate use of the first cervical cancer vaccine (Gardasil, Merck & Co.; Whitehouse Station, NJ), the Food and [...]

The New England Journal of Medicine recently published results from two phase III studies of Merck's cervical cancer vaccine, Gardasil [quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine]. [...]

Merck & Co.'s VAQTA (hepatitis A vaccine, inactivated) can now be used in children as young as one year of age. Previously approved for use in patients aged two years [...]

AstraZeneca, Wilmington, Del., (800) 236-9939, has a new administration formulation for its proton pump inhibitor delayed-release Nexium (esomeprazole magnesium) capsules. Nexium IV (esomeprazole sodium) for Injection is administered once daily [...]

New indication for losartan Merck Sharp and Dohme has announced that Cozaar (losartan) can now be prescribed for the management of hypertensive patients with left ventricular hypertrophy (LVH) to reduce [...]

A formulation of 4 mg oral granules of montelukast (Singulair, Merck) is now available for once-daily prevention and chronic treatment of asthma in children aged 12 months to 5 [...]

Nausea and vomiting are common complications of cancer chemotherapy. These side effects can be severely debilitating and disruptive and often lead to patients refusing to continue their chemotherapy. Patients now [...]

Safety and efficacy data on alendronate (Fosamax, Merck) have now been extended to the 10-year mark, showing no increase in adverse effects and continued bone mineral density (BMD) gains with [...]

Two angiotensin II receptor blockers (ARBs) have gained new indications for kidney disease in type 2 diabetes patients. Irbesartan (Avapro, Bristol-Myers Squibb and Sanofi-Synthelabo) is indicated for treatment of diabetic [...]

The label for simvastatin (Zocor, Merck) has been changed to include a warning about a potentially dangerous drug interaction with amiodarone (Cordarone, Wyeth), Merck announced. Those taking amiodarone should not [...]

Results of a landmark animal study published in the Journal of Bone and Mineral Research indicate that the COX-2 inhibitors celecoxib (Celebrex, Pharmacia) and rofecoxib (Vioxx, Merck) may impair the [...]

The FDA has approved changes to the prescribing information for rofecoxib (Vioxx) to include results from the VIGOR study, Merck has announced. Rofecoxib 25 mg once daily has also received [...]

According to FDA, Vioxx (rofecoxib, Merck & Co.) has been associated with five cases of nonbacterial meningitis. A report published in the March 25 issue of Archives of Internal Medicine [...]

A 17-year-old male presents with severe, throbbing, unremitting headache that has lasted 16 days. Two days prior to this, the patient was seen in the emergency room and received intravenous [...]

Ertapenem for injection Merck Once-daily injectable carbapenem for treatment of various infections The antibiotic ertapenem has been approved for treatment of adults with moderate to severe forms of the following: [...]

Reviewed by Peter A. Netland, MD, PhD Memphis--Dual therapy with brimonidine (Alphagan, Allergan) and latanoprost (Xalatan, Pharmacia & Upjohn) was more effective than timolol/dorzolamide (Cosopt, Merck) in reducing IOP in [...]

CHICAGO - Asthma patients on a leukotriene modifier were less likely to need oral corticosteroid rescue during 10 months of follow-up than were patients on an inhaled corticosteroid, according to [...]

How the new 'SUPER STATIN' will shake up the cholesterol-lowering market AstraZeneca's Crestor is expected to have a major impact on prescribing patterns in the cholesterol-lowering market. While it has [...]