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2. Development of a Transcultural Social Ethical and Integrated Care Model, for Dependent and Older People Populations at Risk of Exclusion in the Mediterranean Sea Basin (TEC-MED): A Research Protocol

Author

Ana María Porcel-Gálvez, Elena Fernández-García, Soledad Vázquez-Santiago, Sergio Barrientos-Trigo, María Dolores Mateos-Garcia, Mercedes Bueno-Ferrán, Jalila El Ati, Hajer Aounallah-Skhiri, and Marta Lima-Serrano

Subjects
dependency, integrated care, older people, risk of exclusion, transcultural, Medicine (General), R5-920
Abstract

Background: Higher life expectancy has produced a higher older people porpulation, not necessarily with a consistent quality of life, showing a high rate of vulnerability and dependence. The current social and health crisis situation has highlighted the need to create new integrated models of care that could be translated into social and health policies. Objective: The present study aims to develop, test, and validate an innovative integrated care model for older people with dependence and at risk of social exclusion and their caregivers. Methods: The TEC-MED project participants are nine project partners and six associated partners, with geographic coverage from six countries in the Mediterranean basin, Spain, Tunisia, Italy, Lebanon, Egypt, and Greece. Project coordination will take place at three different levels, macro, meso and micro, through six work packages. The pilot phase uses qualitative-quantitative method to assess the impact of the TEC-MED project, it is expected to train 36 Training Agents, six per country, who apply to a total of 28,200 people (mainly elders and their caregivers). Conclusion: The study proposes a new social integrated care organizational model focused on the integration of social and health care, comprising the governance model; the organization structure and the skills profiles for the caring personnel. Abstracta Antecedentes: La mayor esperanza de vida ha generado un incremento en la población de personas mayores, sin embargo, no necesariamente se ha traducido en una mejora constante de la calidad de vida, evidenciándose una alta tasa de vulnerabilidad y dependencia. La actual crisis social y sanitaria ha resaltado la necesidad de crear nuevos modelos integrados de atención que puedan traducirse en políticas sociales y de salud. Objetivo: El presente estudio tiene como objetivo desarrollar, probar y validar un modelo innovador de atención integrada para personas mayores con dependencia y/o en riesgo de exclusión social, así como para sus personas cuidadoras. Métodos: Los participantes del proyecto TEC-MED son nueve socios del proyecto y seis asociados, con cobertura geográfica en seis países de la cuenca del Mediterráneo: España, Túnez, Italia, Líbano, Egipto y Grecia. La coordinación del proyecto se llevará a cabo en tres niveles diferentes, macro, meso y micro, y a través de seis paquetes de trabajo. La fase piloto utiliza un método cualitativo-cuantitativo para evaluar el impacto del proyecto TEC-MED. Se espera capacitar a 36 Agentes de Formación, seis por país, quienes aplicarán el proyecto a un total de 28,200 personas (principalmente personas mayores y sus personas cuidadoras.). Conclusión: El estudio propone un nuevo modelo organizativo de atención social integrada, centrado en la integración de la atención social y sanitaria, que comprende el modelo de gobernanza, la estructura organizativa y los perfiles de competencias del personal de cuidado. Palabras Claves: Atención integrada; Dependencia; Personas mayores; Riesgo de exclusión; Transcultural

Published
2024
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3. Report of Editors: A year's work

Author

Montserrat Antón-Gamero, Alejandro Ávila-Álvarez, Josep Vicent Balaguer-Martínez, Mercedes Bueno Campaña, and Rafael Galera Martínez

Subjects
Pediatrics, RJ1-570
Published
2023
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6. MR-Proadrenomedullin as biomarker of renal damage in urinary tract infection in children

Author

Rafael Peñalver Penedo, Marta Rupérez Lucas, Luis Antonio Álvarez-Sala Walther, Alicia Torregrosa Benavent, María Luisa Casas Losada, Luis Bañuelos Andrio, Ana Belén Rebolledo Poves, and Mercedes Bueno Campaña

Subjects
Proadrenomedullin, Biomarker, Urinary tract infection, Pediatric, Renal scarring, Pediatrics, RJ1-570
Abstract

Abstract Background Midregional-proadrenomedullin (MR-proADM) is a useful prognostic peptide in severe infectious pathologies in the adult population. However, there are no studies that analyze its utility in febrile urinary tract infection (fUTI) in children. An accurate biomarker would provide an early detection of patients with kidney damage, avoiding other invasive tests like renal scintigraphy scans. Our objective is to study the usefulness of MR-proADM as a biomarker of acute and chronic renal parenchymal damage in fUTI within the pediatric population. Methods A prospective cohort study was conducted in pediatric patients with fUTI between January 2015 and December 2018. Plasma and urine MR-proADM levels were measured at admission in addition to other laboratory parameters. After confirmation of fUTI, renal scintigraphy scans were performed during the acute and follow-up stages. A descriptive study has been carried out and sensitivity, specificity and ROC curves for MR-proADM, C-reactive protein, and procalcitonin were calculated. Results 62 pediatric patients (34 female) were enrolled. Scintigraphy showed acute pyelonephritis in 35 patients (56.5%). Of those patients, the median of plasmatic MR-proADM (P-MR-proADM) showed no differences compared to patients without pyelonephritis. 7 patients (11.3%) developed renal scars (RS). Their median P-MR-proADM levels were 1.07 nmol/L (IQR 0.66–1.59), while in patients without RS were 0.48 nmol/L (0.43–0.63) (p

Published
2021
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7. Why Does the Automation Say One Thing but Does Something Else? Effect of the Feedback Consistency and the Timing of Error on Trust in Automated Driving

Author

J. B. Manchon, Romane Beaufort, Mercedes Bueno, and Jordan Navarro

Subjects
trust in automation, automated driving, feedback, driver’s behavior, critical situations, Information technology, T58.5-58.64
Abstract

Driving automation deeply modifies the role of the human operator behind the steering wheel. Trust is required for drivers to engage in such automation, and this trust also seems to be a determinant of drivers’ behaviors during automated drives. On the one hand, first experiences with automation, either positive or not, are essential for drivers to calibrate their level of trust. On the other hand, an automation that provides feedback about its own level of capability to handle a specific driving situation may also help drivers to calibrate their level of trust. The reported experiment was undertaken to examine how the combination of these two effects will impact the driver trust calibration process. Four groups of drivers were randomly created. Each experienced either an early (i.e., directly after the beginning of the drive) or a late (i.e., directly before the end of it) critical situation that was poorly handled by the automation. In addition, they experienced either a consistent continuous feedback (i.e., that always correctly informed them about the situation), or an inconsistent one (i.e., that sometimes indicated dangers when there were none) during an automated drive in a driving simulator. Results showed the early- and poorly-handled critical situation had an enduring negative effect on drivers’ trust development compared to drivers who did not experience it. While being correctly understood, inconsistent feedback did not have an effect on trust during properly managed situations. These results suggest that the performance of the automation has the most severe influence on trust, and the automation’s feedback does not necessarily have the ability to influence drivers’ trust calibration during automated driving.

Published
2022
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8. Implementing stakeholder engagement to explore alternative models of consent: An example from the PREP-IT trials

Author

Guillermo Pechero, Jr., MD, Branden Pfaff, Mayank Rao, David Pogorzelski, Paula McKay, Ella Spicer, Andrea Howe, Haley K. Demyanovich, Debra L. Sietsema, Michael F. McTague, Lolita Ramsey, Martha Holden, Joshua Rudnicki, Jeff Wells, Michelle Medeiros, Gerard P. Slobogean, Sheila Sprague, Jeffrey Wells, Mohit Bhandari, Robert V. O'Toole, Jean-Claude D'Alleyrand, Andrew Eglseder, Aaron Johnson, Christopher Langhammer, Christopher Lebrun, Theodore Manson, Jason Nascone, Ebrahim Paryavi, Raymond Pensy, Andrew Pollak, Marcus Sciadini, Yasmin Degani, Nathan N. O'Hara, Katherine Joseph, Megan Camara, Anthony D. Harris, Daniel C. Mullins, Lehana Thabane, Amber Wood, Gregory J. Della Rocca, Joan Hebden, Kyle J. Jeray, Lucas Marchand, Lyndsay M. O'Hara, Robert Zura, Michael J. Gardner, Jenna Blasman, Jonah Davies, Stephen Liang, Monica Taljaard, P.J. Devereaux, Gordon H. Guyatt, Diane Heels-Ansdell, Debra Marvel, Jana Palmer, Jeff Friedrich, Ms Frances Grissom, I. Leah Gitajn, Saam Morshed, Bradley A. Petrisor, Franca Mossuto, Manjari G. Joshi, Justin Fowler, Jessica Rivera, Max Talbot, Shannon Dodds, Alisha Garibaldi, Silvia Li, Uyen Nguyen, Alejandra Rojas, Taryn Scott, Gina Del Fabbro, Olivia Paige Szasz, Haley Demyanovich, Kelly Little, C. Daniel Mullins, Eric Kettering, Diamond Hale, Brad A. Petrisor, Herman Johal, Bill Ristevski, Dale Williams, Matthew Denkers, Krishan Rajaratnam, Jamal Al-Asiri, Jordan Leonard, Francesc A. Marcano-Fernández, Jodi Gallant, Federico Persico, Marko Gjorgjievski, Annie George, Roman M. Natoli, Greg E. Gaski, Todd O. McKinley, Walter W. Virkus, Anthony T. Sorkin, Jan P. Szatkowski, Joseph R. Baele, Brian H. Mullis, Lauren C. Hill, Andrea Hudgins, Patrick Osborn, Sarah Pierrie, Eric Martinez, Joseph Kimmel, John D. Adams, Michael L. Beckish, Christopher C. Bray, Timothy R. Brown, Andrew W. Cross, Timothy Dew, Gregory K. Faucher, Richard W. Gurich, Jr., David E. Lazarus, S. John Millon, M. Jason Palmer, Scott E. Porter, Thomas M. Schaller, Michael S. Sridhar, John L. Sanders, L. Edwin Rudisill, Jr., Michael J. Garitty, Andrew S. Poole, Michael L. Sims, Clark M. Walker, Robert M. Carlisle, II, Erin Adams Hofer, Brandon S. Huggins, Michael D. Hunter, William A. Marshall, Shea Bielby Ray, Cory D. Smith, Kyle M. Altman, Julia C. Bedard, Markus F. Loeffler, Erin R. Pichiotino, Austin A. Cole, Ethan J. Maltz, Wesley Parker, T. Bennett Ramsey, Alex Burnikel, Michael Colello, Russell Stewart, Jeremy Wise, M. Christian Moody, Stephanie L. Tanner, Rebecca G. Snider, Christine E. Townsend, Kayla H. Pham, Abigail Martin, Emily Robertson, Theodore Miclau, Utku Kandemir, Meir Marmor, Amir Matityahu, R. Trigg McClellan, Eric Meinberg, David Shearer, Paul Toogood, Anthony Ding, Erin Donohoe, Jothi Murali, Tigist Belaye, Eleni Berhaneselase, Alexandra Paul, Kartik Garg, Joshua L. Gary, Stephen J. Warner, John W. Munz, Andrew M. Choo, Timothy S. Achor, Milton L. “Chip” Routt, Guillermo Pechero, Adam Miller, Jennifer E. Hagen, Matthew Patrick, Richard Vlasak, Thomas Krupko, Kalia Sadasivan, Chris Koenig, Daniel Bailey, Daniel Wentworth, Chi Van, Justin Schwartz, Niloofar Dehghan, Clifford B. Jones, J. Tracy Watson, Michael McKee, Ammar Karim, Michael Talerico, Alyse Williams, Tayler Dykes, William T. Obremskey, Amir Alex Jahangir, Manish Sethi, Robert Boyce, Daniel J. Stinner, Phillip Mitchell, Karen Trochez, Andres Rodriguez, Vamshi Gajari, Elsa Rodriguez, Charles Pritchett, Christina Boulton, Jason Lowe, Jason Wild, John T. Ruth, Michel Taylor, Andrea Seach, Sabina Saeed, Hunter Culbert, Alejandro Cruz, Thomas Knapp, Colin Hurkett, Maya Lowney, Michael Prayson, Indresh Venkatarayappa, Brandon Horne, Jennifer Jerele, Linda Clark, Francesc Marcano-Fernández, Montsant Jornet-Gibert, Laia Martínez-Carreres, David Martí-Garín, Jorge Serrano-Sanz, Joel Sánchez-Fernández, Matsuyama Sanz-Molero, Alejandro Carballo, Xavier Pelfort, Francesc Acerboni-Flores, Anna Alavedra-Massana, Neus Anglada-Torres, Alexandre Berenguer, Jaume Cámara-Cabrera, Ariadna Caparros-García, Ferran Fillat-Gomà, Ruben Fuentes-López, Ramona Garcia-Rodriguez, Nuria Gimeno-Calavia, Guillem Graells-Alonso, Marta Martínez-Álvarez, Patricia Martínez-Grau, Raúl Pellejero-García, Ona Ràfols-Perramon, Juan Manuel Peñalver, Mònica Salomó Domènech, Albert Soler-Cano, Aldo Velasco-Barrera, Christian Yela-Verdú, Mercedes Bueno-Ruiz, Estrella Sánchez-Palomino, Ernesto Guerra-Farfan, Jordi Tomas-Hernandez, Jordi Teixidor-Serra, Vicente Molero-Garcia, Jordi Selga-Marsa, Juan Antonio Porcel-Vasquez, Jose Vicente Andres-Peiro, Joan Minguell-Monyart, Yaiza Garcia-Sanchez, Jorge Nuñez-Camarena, Eladia Tauste-Rubio, Marta Gonzalez-Amigo, Nicholas M. Romeo, Heather A. Vallier, Mary A. Breslin, Joanne Fraifogl, Eleanor S. Wilson, Leanne K. Wadenpfuhl, Paul G. Halliday, Darius G. Viskontas, Kelly L. Apostle, Dory S. Boyer, Farhad O. Moola, Bertrand H. Perey, Trevor B. Stone, H. Michael Lemke, Mauri Zomar, Chen “Brenda” Fan, Kyrsten Payne, Kevin Phelps, Michael Bosse, Madhav Karunakar, Laurence Kempton, Stephen Sims, Joseph Hsu, Rachel Seymour, Christine Churchill, Claire Bartel, Robert Miles Mayberry, Maggie Brownrigg, Cara Girardi, Ada Mayfield, Robert A. Hymes, Cary C. Schwartzbach, Jeff E. Schulman, A. Stephen Malekzadeh, Michael A. Holzman, James S. Ahn, Farhanaz Panjshiri, Sharmistha Das, Antoinisha D. English, Sharon M. Haaser, Jaslynn A.N. Cuff, Holly Pilson, Eben A. Carroll, Jason J. Halvorson, Sharon Babcock, J. Brett Goodman, Martha B. Holden, Debra Bullard, Wendy Williams, Thomas F. Higgins, Justin M. Haller, David L. Rothberg, Lucas S. Marchand, Ashley Neese, Mark Russell, Zachary M. Olsen, Marcus Coe, Kevin Dwyer, Devin S. Mullin, Clifford A. Reilly, Peter DePalo, Amy E. Hall, Marilyn Heng, Mitchel B. Harris, R. Malcolm Smith, David W. Lhowe, John G. Esposito, Mira Bansal, Patrick F. Bergin, George V. Russell, Matthew L. Graves, John Morellato, Heather K. Champion, Leslie N. Johnson, Sheketha L. McGee, Eldrin L. Bhanat, Samir Mehta, Derek Donegan, Jaimo Ahn, Annamarie Horan, Mary Dooley, Ashley Kuczinski, Ashley Iwu, David Potter, Robert VanDemark, III, Troy Hollinsworth, Michael J. Weaver, Arvind G. von Keudell, Elizabeth M. Allen, Todd Jaeblon, Robert Beer, Mark J. Gage, Rachel M. Reilly, and Cindy Sparrow

Subjects
Cluster randomized crossover, Stakeholder engagement, Consent, Deferred consent, Trial design, Patient advisors, Medicine (General), R5-920
Abstract

Introduction: Cluster randomized crossover trials are often faced with a dilemma when selecting an optimal model of consent, as the traditional model of obtaining informed consent from participant's before initiating any trial related activities may not be suitable. We describe our experience of engaging patient advisors to identify an optimal model of consent for the PREP-IT trials. This paper also examines surrogate measures of success for the selected model of consent. Methods: The PREP-IT program consists of two multi-center cluster randomized crossover trials that engaged patient advisors to determine an optimal model of consent. Patient advisors and stakeholders met regularly and reached consensus on decisions related to the trial design including the model for consent. Patient advisors provided valuable insight on how key decisions on trial design and conduct would be received by participants and the impact these decisions will have. Results: Patient advisors, together with stakeholders, reviewed the pros and cons and the requirements for the traditional model of consent, deferred consent, and waiver of consent. Collectively, they agreed upon a deferred consent model, in which patients may be approached for consent after their fracture surgery and prior to data collection. The consent rate in PREP-IT is 80.7%, and 0.67% of participants have withdrawn consent for participation. Discussion: Involvement of patient advisors in the development of an optimal model of consent has been successful. Engagement of patient advisors is recommended for other large trials where the traditional model of consent may not be optimal.

Published
2021
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9. Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial

Author

David Pogorzelski, Uyen Nguyen, Paula McKay, Lehana Thabane, Megan Camara, Lolita Ramsey, Rachel Seymour, J. Brett Goodman, Sheketha McGee, Joanne Fraifogl, Andrea Hudgins, Stephanie L. Tanner, Mohit Bhandari, Gerard P. Slobogean, Sheila Sprague, Jeffrey Wells, Jean-Claude D'Alleyrand, Anthony D. Harris, Daniel C. Mullins, Amber Wood, Gregory J. Della Rocca, Joan Hebden, Kyle J. Jeray, Lucas Marchand, Lyndsay M. O'Hara, Robert Zura, Michael J. Gardner, Jenna Blasman, Jonah Davies, Stephen Liang, Monica Taljaard, P.J. Devereaux, Gordon H. Guyatt, Diane Heels-Ansdell, Debra Marvel, Jana Palmer, Jeff Friedrich, Nathan N. O'Hara, Ms. Frances Grissom, I. Leah Gitajn, Saam Morshed, Robert V. O'Toole, Bradley A. Petrisor, Franca Mossuto, Manjari G. Joshi, Justin Fowler, Jessica Rivera, Max Talbot, Shannon Dodds, Alisha Garibaldi, Silvia Li, Alejandra Rojas, Taryn Scott, Gina Del Fabbro, Olivia Paige Szasz, Andrea Howe, Joshua Rudnicki, Haley Demyanovich, Kelly Little, C. Daniel Mullins, Michelle Medeiros, Eric Kettering, Diamond Hale, Andrew Eglseder, Aaron Johnson, Christopher Langhammer, Christopher Lebrun, Theodore Manson, Jason Nascone, Ebrahim Paryavi, Raymond Pensy, Andrew Pollak, Marcus Sciadini, Yasmin Degani, Haley K. Demyanovich, Katherine Joseph, Brad A. Petrisor, Herman Johal, Bill Ristevski, Dale Williams, Matthew Denkers, Krishan Rajaratnam, Jamal Al-Asiri, Jordan Leonard, Francesc A. Marcano-Fernández, Jodi Gallant, Federico Persico, Marko Gjorgjievski, Annie George, Roman M. Natoli, Greg E. Gaski, Todd O. McKinley, Walter W. Virkus, Anthony T. Sorkin, Jan P. Szatkowski, Joseph R. Baele, Brian H. Mullis, Lauren C. Hill, Patrick Osborn, Sarah Pierrie, Eric Martinez, Joseph Kimmel, John D. Adams, Michael L. Beckish, Christopher C. Bray, Timothy R. Brown, Andrew W. Cross, Timothy Dew, Gregory K. Faucher, Richard W. Gurich, Jr., David E. Lazarus, S. John Millon, M. Jason Palmer, Scott E. Porter, Thomas M. Schaller, Michael S. Sridhar, John L. Sanders, L. Edwin Rudisill, Jr., Michael J. Garitty, Andrew S. Poole, Michael L. Sims, Clark M. Walker, Robert M. Carlisle, II, Erin Adams Hofer, Brandon S. Huggins, Michael D. Hunter, William A. Marshall, Shea Bielby Ray, Cory D. Smith, Kyle M. Altman, Julia C. Bedard, Markus F. Loeffler, Erin R. Pichiotino, Austin A. Cole, Ethan J. Maltz, Wesley Parker, T. Bennett Ramsey, Alex Burnikel, Michael Colello, Russell Stewart, Jeremy Wise, M. Christian Moody, Rebecca G. Snider, Christine E. Townsend, Kayla H. Pham, Abigail Martin, Emily Robertson, Theodore Miclau, Utku Kandemir, Meir Marmor, Amir Matityahu, R. Trigg McClellan, Eric Meinberg, David Shearer, Paul Toogood, Anthony Ding, Erin Donohue, Tigist Belaye, Eleni Berhaneselase, Alexandra Paul, Kartik Garg, Joshua L. Gary, Stephen J. Warner, John W. Munz, Andrew M. Choo, Timothy S. Achor, Milton L. “Chip” Routt, Mayank Rao, Guillermo Pechero, Adam Miller, Jennifer E. Hagen, Matthew Patrick, Richard Vlasak, Thomas Krupko, Kalia Sadasivan, Chris Koenig, Daniel Bailey, Daniel Wentworth, Chi Van, Justin Schwartz, Niloofar Dehghan, Clifford B. Jones, J Tracy Watson, Michael McKee, Ammar Karim, Michael Talerico, Debra L. Sietsema, Alyse Williams, Tayler Dykes, William T. Obremskey, Amir Alex Jahangir, Manish Sethi, Robert Boyce, Daniel J. Stinner, Phillip Mitchell, Karen Trochez, Andres Rodriguez, Vamshi Gajari, Elsa Rodriguez, Charles Pritchett, Christina Boulton, Jason Lowe, Jason Wild, John T. Ruth, Michel Taylor, Andrea Seach, Sabina Saeed, Hunter Culbert, Alejandro Cruz, Thomas Knapp, Colin Hurkett, Maya Lowney, Michael Prayson, Indresh Venkatarayappa, Brandon Horne, Jennifer Jerele, Linda Clark, Francesc Marcano-Fernández, Montsant Jornet-Gibert, Laia Martínez-Carreres, David Martí-Garín, Jorge Serrano-Sanz, Joel Sánchez-Fernández, Matsuyama Sanz-Molero, Alejandro Carballo, Xavier Pelfort, Francesc Acerboni-Flores, Anna Alavedra-Massana, Neus Anglada-Torres, Alexandre Berenguer, Jaume Cámara-Cabrera, Ariadna Caparros-García, Ferran Fillat-Gomà, Ruben Fuentes-López, Ramona Garcia-Rodriguez, Nuria Gimeno-Calavia, Guillem Graells-Alonso, Marta Martínez-Álvarez, Patricia Martínez-Grau, Raúl Pellejero-García, Ona Ràfols-Perramon, Juan Manuel Peñalver, Mònica Salomó Domènech, Albert Soler-Cano, Aldo Velasco-Barrera, Christian Yela-Verdú, Mercedes Bueno-Ruiz, Estrella Sánchez-Palomino, Ernesto Guerra, Yaiza García, Nicholas M. Romeo, Heather A. Vallier, Mary A. Breslin, Eleanor S. Wilson, Leanne K. Wadenpfuhl, Paul G. Halliday, Darius G. Viskontas, Kelly L. Apostle, Dory S. Boyer, Farhad O. Moola, Bertrand H. Perey, Trevor B. Stone, H. Michael Lemke, Mauri Zomar, Ella Spicer, Chen “Brenda” Fan, Kyrsten Payne, Kevin Phelps, Michael Bosse, Madhav Karunakar, Laurence Kempton, Stephen Sims, Joseph Hsu, Christine Churchill, Claire Bartel, Robert Miles Mayberry, Maggie Brownrigg, Cara Girardi, Ada Mayfield, Robert A. Hymes, Cary C. Schwartzbach, Jeff E. Schulman, A. Stephen Malekzadeh, Michael A. Holzman, James S. Ahn, Farhanaz Panjshiri, Sharmistha Das, Antoinisha D. English, Sharon M. Haaser, Jaslynn A.N. Cuff, Holly Pilson, Eben A. Carroll, Jason J. Halvorson, Sharon Babcock, Martha B. Holden, Debra Bullard, Wendy Williams, Thomas F. Higgins, Justin M. Haller, David L. Rothberg, Ashley Neese, Mark Russell, Marcus Coe, Kevin Dwyer, Devin S. Mullin, Clifford A. Reilly, Peter DePalo, Amy E. Hall, Marilyn Heng, Mitchel B. Harris, R. Malcolm Smith, David W. Lhowe, John G. Esposito, Mira Bansal, Patrick F. Bergin, George V. Russell, Matthew L. Graves, John Morellato, Heather K. Champion, Leslie N. Johnson, Sheketha L. McGee, Eldrin L. Bhanat, Samir Mehta, Derek Donegan, Jaimo Ahn, Annamarie Horan, Mary Dooley, Ashley Kuczinski, Ashley Iwu, David Potter, Robert VanDemark, III, Branden Pfaff, Troy Hollinsworth, Michael J. Weaver, Arvind G. von Keudell, Michael F. McTague, Elizabeth M. Allen, Todd Jaeblon, Robert Beer, Mark J. Gage, Rachel M. Reilly, and Cindy Sparrow

Subjects
Sampling, Pragmatic, Cluster crossover, Sampling framework, Work flow, Sampling strategy, Medicine (General), R5-920
Abstract

Introduction: Pragmatic trials in comparative effectiveness research assess the effects of different treatment, therapeutic, or healthcare options in clinical practice. They are characterized by broad eligibility criteria and large sample sizes, which can lead to an unmanageable number of participants, increasing the risk of bias and affecting the integrity of the trial. We describe the development of a sampling strategy tool and its use in the PREPARE trial to circumvent the challenge of unmanageable work flow. Methods: Given the broad eligibility criteria and high fracture volume at participating clinical sites in the PREPARE trial, a pragmatic sampling strategy was needed. Using data from PREPARE, descriptive statistics were used to describe the use of the sampling strategy across clinical sites. A Chi-square test was performed to explore whether use of the sampling strategy was associated with a reduction in the number of missed eligible patients. Results: 7 of 20 clinical sites (35%) elected to adopt a sampling strategy. There were 1539 patients excluded due to the use of the sampling strategy, which represents 30% of all excluded patients and 20% of all patients screened for participation. Use of the sampling strategy was associated with lower odds of missed eligible patients (297/4545 (6.5%) versus 341/3200 (10.7%) p

Published
2021
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10. Anales de Pediatría: We take over

Author

Montserrat Antón Gamero, Alejandro Ávila Álvarez, Josep Vicent Balaguer-Martínez, Mercedes Bueno Campaña, and Víctor Manuel Navas López

Subjects
Pediatrics, RJ1-570
Published
2021
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17. Evaluation of the impact of the Spanish Consensus Document on the approach to osteoarticular infections in Spain through the Paediatrics Osteoarticular Infections Network (RIOPED)

Author

Rueda, Rosa Alcobendas, Garulo, Daniel Clemente, Santaeufemia, F. José Sanz, Campos, Leticia Martínez, García, Alfredo Tagarro, Fontecha, César G., Melendo-Pérez, Susana, Lovillo, Marisol Camacho, Neyra, Lola Falcón, Cruz, M. José Lirola, Gil, Elena Colino, Carreño, Patricia Tejera, Canals, Luis Mayol, Zarketa, Daniel Domenech, Campaña, M. Mercedes Bueno, Méndez, Carlos Pérez, Gordillo, Neus Rius, Cardona, Verónica, Colom, Jaime Carrasco, Fernández, Antonio Conejo, Ramírez, Marta García, Delgado, Rafael Díez, Ordónez, Carmen Vázquez, Tejada, Enrique Otheo de, Gianzo, José Couceiro, Arranz, Leonor, García-Pardos, Carmen, Piñeiro-Pérez, Roi, Mancheño, Beatriz Bravo, López-Molina, Inmaculada, Acevedo, Adriana Vidal, Antón, María Penín, Coll, M. Teresa, Soler, Berta Pujol, Pérez, Pilar Ranchal, Morales, Sara Pons, Sevilla, Belén, Hernández, María Méndez, García-Mazarío, M. Jesús, Martín, César Gavilán, Fernández-Cooke, Elisa, Canet, Anna, Jiménez, Marta Ruiz, González, Marina, Rodríguez, Lourdes García, Moreno, Carmen, Lizarbe, Miren Oscoz, Martín-Pedraz, Laura, Lillo, Miguel Lillo, Cepillo, Antonio J., Soler-Palacín, Pere, Ramakers, Jan, Gasaball, Olga Calavia, Ramo, Rebeca Lahoz, Barrero, Pedro Terol, Vilchez, M. José Muñoz, Pérez, Victoria Fumadó, Camps, Silvia Urraca, Rodríguez, Elena Urbaneja, Ortega, M. José Cilleruelo, López, Agustín López, Solas, Valentín Pineda, Pedrab, Carla Monterde, Molina, Rosa Roldán, Masegosa-Casanova, Sandra, Rodríguez, Paula Alcañiz, Ruíz, Ana Menasalvas, Arístegui-Fernández, Javier, Garrote, Elisa, Martinón-Torres, Federico, Rivero-Calle, Irene, Ramos, José Tomás, Ramos, Marta Illán, Montero, Beatriz Jiménez, Pinedo, Begoña Losada, Ibáñez, Borja Guarch, Serrano, Marcelina Algar, García, M. Dolores, Pereira, Elena, Rodríguez-Blanco, Silvia, Fontán, Manuel Muñiz, Reyes, Sagrario Bustabab, Claros, Antonio Medina, Oñós, Isabel Vives, Perelló, M. Concepción Mir, Barreiro, Natalia Cerdeira, Barnés, María Ríos, Patudo, Isabel Vara, Martínez-Regueira, Soledad, Domenech, Raquel Marín, Vílchez, Juan Salvador, Moreno, Jesús de la Cruz, Laleona, Carmelo Guerrero, Alonso, Matilde Bustillo, Meléndez, Leticia Merino, Martín, Azucena García, Núñez Cuadros, Esmeralda, Calvo, Cristina, and Saavedra-Lozano, Jesús

Published
2020
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18. Evaluación del impacto del Documento de Consenso español sobre el abordaje de las infecciones osteoarticulares en nuestro medio a través de la Red de Infecciones Osteoarticulares Pediátricas (RIOPed)

Author

Rueda, Rosa Alcobendas, Garulo, Daniel Clemente, Santaeufemia, F. José Sanz, Campos, Leticia Martínez, García, Alfredo Tagarro, Fontecha, César G., Melendo-Pérez, Susana, Lovillo, Marisol Camacho, Neyra, Lola Falcón, Cruz, M. José Lirola, Gil, Elena Colino, Carreño, Patricia Tejera, Canals, Luis Mayol, Zarketa, Daniel Domenech, Campaña, M. Mercedes Bueno, Méndez, Carlos Pérez, Gordillo, Neus Rius, Cardona, Verónica, Colom, Jaime Carrasco, Fernández, Antonio Conejo, Ramírez, Marta García, Delgado, Rafael Díez, Ordónez, Carmen Vázquez, Tejada, Enrique Otheo de, Gianzo, José Couceiro, Arranz, Leonor, García-Pardos, Carmen, Piñeiro-Pérez, Roi, Mancheño, Beatriz Bravo, López-Molina, Inmaculada, Acevedo, Adriana Vidal, Antón, María Penín, Coll, M. Teresa, Soler, Berta Pujol, Pérez, Pilar Ranchal, Morales, Sara Pons, Sevilla, Belén, Hernández, María Méndez, García-Mazarío, M. Jesús, Martín, César Gavilán, Fernández-Cooke, Elisa, Canet, Anna, Jiménez, Marta Ruiz, González, Marina, Rodríguez, Lourdes García, Moreno, Carmen, Lizarbe, Miren Oscoz, Martín-Pedraz, Laura, Lillo, Miguel Lillo, Cepillo, Antonio J., Soler-Palacín, Pere, Ramakers, Jan, Gasaball, Olga Calavia, Ramo, Rebeca Lahoz, Barrero, Pedro Terol, Vilchez, M. José Muñoz, Pérez, Victoria Fumadó, Camps, Silvia Urraca, Rodríguez, Elena Urbaneja, Ortega, M. José Cilleruelo, López, Agustín López, Solas, Valentín Pineda, Pedrab, Carla Monterde, Molina, Rosa Roldán, Masegosa-Casanova, Sandra, Rodríguez, Paula Alcañiz, Ruíz, Ana Menasalvas, Arístegui-Fernández, Javier, Garrote, Elisa, Martinón-Torres, Federico, Rivero-Calle, Irene, Ramos, José Tomás, Ramos, Marta Illán, Montero, Beatriz Jiménez, Pinedo, Begoña Losada, Ibáñez, Borja Guarch, Serrano, Marcelina Algar, García, M. Dolores, Pereira, Elena, Rodríguez-Blanco, Silvia, Fontán, Manuel Muñiz, Reyes, Sagrario Bustabab, Claros, Antonio Medina, Oñós, Isabel Vives, Perelló, M. Concepción Mir, Barreiro, Natalia Cerdeira, Barnés, María Ríos, Patudo, Isabel Vara, Martínez-Regueira, Soledad, Domenech, Raquel Marín, Vílchez, Juan Salvador, Moreno, Jesús de la Cruz, Laleona, Carmelo Guerrero, Alonso, Matilde Bustillo, Meléndez, Leticia Merino, Martín, Azucena García, Núñez Cuadros, Esmeralda, Calvo Rey, Cristina, and Saavedra-Lozano, Jesús

Published
2020
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19. The impact of heterotopic ossification prophylaxis after surgical fixation of acetabular fractures: national treatment patterns and related outcomes

Author

Adam Boissonneault, Nathan O Hara, David Pogorzelski, Lucas Marchand, Thomas Higgins, Leah Gitajn, Mark J. Gage, Roman M. Natoli, Ishani Sharma, Sarah Pierrie, Robert V O’Toole, Sheila Sprague, Gerard Slobogean, Gerard P. Slobogean, Jeffrey Wells, Mohit Bhandari, Anthony D. Harris, C. Daniel Mullins, Lehana Thabane, Amber Wood, Gregory J. Della Rocca, Joan Hebden, Kyle J. Jeray, Lucas S. Marchand, Lyndsay M. O'Hara, Robert Zura, Christopher Lee, Joseph Patterson, Michael J. Gardner, Jenna Blasman, Jonah Davies, Stephen Liang, Monica Taljaard, PJ Devereaux, Gordon H. Guyatt, Diane Heels-Ansdell, Debra Marvel, Jana Palmer Jeffrey Wells, Jeff Friedrich, Nathan N. O'Hara, Frances Grissom, I. Leah Gitajn, Saam Morshed, Robert V. O'Toole, Bradley A. Petrisor, Franca Mossuto, Manjari G. Joshi, Jean-Claude D'Alleyrand, Justin Fowler, Jessica Rivera, Max Talbot, Shannon Dodds, Silvia Li, Alejandra Rojas, Gina Del Fabbro, Olivia Paige Szasz, Paula McKay, Alexandra Minea, Andrea Howe, Haley Demyanovich, Michelle Medeiros, Genevieve Polk, Eric Kettering, Nirmen Mahal, Andrew Eglseder, Aaron Johnson, Christopher Langhammer, Christopher Lebrun, Jason Nascone, Raymond Pensy, Andrew Pollak, Marcus Sciadini, Yasmin Degani, Haley K. Demyanovich, Heather Phipps, Eric Hempen, Christine Holler, Brad A. Petrisor, Herman Johal, Bill Ristevski, Dale Williams, Matthew Denkers, Krishan Rajaratnam, Jamal Al-Asiri, Jodi Gallant, Kaitlyn Pusztai, Sarah MacRae, Sara Renaud, John D. Adams, Michael L. Beckish, Christopher C. Bray, Timothy R. Brown, Andrew W. Cross, Timothy Dew, Gregory K. Faucher, Richard W. Gurich, David E. Lazarus, S. John Millon, M. Christian Moody, M. Jason Palmer, Scott E. Porter, Thomas M. Schaller, Michael S. Sridhar, John L. Sanders, L. Edwin Rudisill, Michael J. Garitty, Andrew S. Poole, Michael L. Sims, Clark M. Walker, Robert Carlisle, Erin A. Hofer, Brandon Huggins, Michael Hunter, William Marshall, Shea B. Ray, Cory Smith, Kyle M. Altman, Erin Pichiotino, Julia C. Quirion, Markus F. Loeffler, Erin R. Pichiotino, Austin A. Cole, Ethan J. Maltz, Wesley Parker, T. Bennett Ramsey, Alex Burnikel, Michael Colello, Russell Stewart, Jeremy Wise, Matthew Anderson, Joshua Eskew, Benjamin Judkins, James M. Miller, Stephanie L. Tanner, Rebecca G. Snider, Christine E. Townsend, Kayla H. Pham, Abigail Martin, Emily Robertson, Emily Bray, J. Wilson Sykes, Krystina Yoder, Kelsey Conner, Harper Abbott, Todd O. McKinley, Walter W. Virkus, Anthony T. Sorkin, Jan P. Szatkowski, Brian H. Mullis, Yohan Jang, Luke A. Lopas, Lauren C. Hill, Courteney L. Fentz, Maricela M. Diaz, Krista Brown, Katelyn M. Garst, Emma W. Denari, Patrick Osborn, Maria Herrera, Theodore Miclau, Meir Marmor, Amir Matityahu, R. Trigg McClellan, David Shearer, Paul Toogood, Anthony Ding, Jothi Murali, Ashraf El Naga, Jennifer Tangtiphaiboontana, Tigist Belaye, Eleni Berhaneselase, Dmitry Pokhvashchev, William T Obremskey, Amir Alex Jahangir, Manish Sethi, Robert Boyce, Daniel J. Stinner, Phillip Mitchell, Karen Trochez, Elsa Rodriguez, Charles Pritchett, Natalie Hogan, A. Fidel Moreno, Jennifer E. Hagen, Matthew Patrick, Richard Vlasak, Thomas Krupko, Michael Talerico, Marybeth Horodyski, Marissa Pazik, Elizabeth Lossada-Soto, Joshua L. Gary, Stephen J Warner, John W. Munz, Andrew M. Choo, Timothy S. Achor, Milton L. 'Chip' Routt, Michael Kutzler, Sterling Boutte, Ryan J. Warth, Michael Prayson, Indresh Venkatarayappa, Brandon Horne, Jennifer Jerele, Linda Clark, Christina Boulton, Jason Lowe, John T. Ruth, Brad Askam, Andrea Seach, Alejandro Cruz, Breanna Featherston, Robin Carlson, Iliana Romero, Isaac Zarif, Niloofar Dehghan, Michael McKee, Clifford B Jones, Debra L Sietsema, Alyse Williams, Tayler Dykes, Ernesto Guerra-Farfan, Jordi Tomas-Hernandez, Jordi Teixidor-Serra, Vicente Molero-Garcia, Jordi Selga-Marsa, Juan Antonio Porcel-Vazquez, Jose Vicente Andres-Peiro, Ignacio Esteban-Feliu, Nuria Vidal-Tarrason, Jordi Serracanta, Jorge Nuñez-Camarena, Maria del Mar Villar-Casares, Jaume Mestre-Torres, Pilar Lalueza-Broto, Felipe Moreira-Borim, Yaiza Garcia-Sanchez, Francesc Marcano-Fernández, Laia Martínez-Carreres, David Martí-Garín, Jorge Serrano-Sanz, Joel Sánchez-Fernández, Matsuyama Sanz-Molero, Alejandro Carballo, Xavier Pelfort, Francesc Acerboni-Flores, Anna Alavedra-Massana, Neus Anglada-Torres, Alexandre Berenguer, Jaume Cámara-Cabrera, Ariadna Caparros-García, Ferran Fillat-Gomà, Ruben Fuentes-López, Ramona Garcia-Rodriguez, Nuria Gimeno-Calavia, Marta Martínez-Álvarez, Patricia Martínez-Grau, Raúl Pellejero-García, Ona Ràfols-Perramon, Juan Manuel Peñalver, Mònica Salomó Domènech, Albert Soler-Cano, Aldo Velasco-Barrera, Christian Yela-Verdú, Mercedes Bueno-Ruiz, Estrella Sánchez-Palomino, Vito Andriola, Matilde Molina-Corbacho, Yeray Maldonado-Sotoca, Alfons Gasset-Teixidor, Jorge Blasco-Moreu, Núria Fernández-Poch, Josep Rodoreda-Puigdemasa, Arnau Verdaguer-Figuerola, Heber Enrique Cueva-Sevieri, Santiago Garcia-Gimenez, Darius G. Viskontas, Kelly L. Apostle, Dory S. Boyer, Farhad O. Moola, Bertrand H. Perey, Trevor B. Stone, H. Michael Lemke, Ella Spicer, Kyrsten Payne, Robert A. Hymes, Cary C. Schwartzbach, Jeff E. Schulman, A. Stephen Malekzadeh, Michael A. Holzman, Greg E. Gaski, Jonathan Wills, Holly Pilson, Eben A. Carroll, Jason J. Halvorson, Sharon Babcock, J. Brett Goodman, Martha B. Holden, Wendy Williams, Taylor Hill, Ariel Brotherton, Nicholas M. Romeo, Heather A Vallier, Anna Vergon, Thomas F. Higgins, Justin M. Haller, David L. Rothberg, Zachary M. Olsen, Abby V. McGowan, Sophia Hill, Morgan K. Dauk, Patrick F. Bergin, George V. Russell, Matthew L. Graves, John Morellato, Sheketha L. McGee, Eldrin L. Bhanat, Ugur Yener, Rajinder Khanna, Priyanka Nehete, Dr. David Potter, Dr. Robert VanDemark, Kyle Seabold, Nicholas Staudenmier, Marcus Coe, Kevin Dwyer, Devin S. Mullin, Theresa A. Chockbengboun, Peter A. DePalo, Kevin Phelps, Michael Bosse, Madhav Karunakar, Laurence Kempton, Stephen Sims, Joseph Hsu, Rachel Seymour, Christine Churchill, Ada Mayfield, Juliette Sweeney, Todd Jaeblon, Robert Beer, Brent Bauer, Sean Meredith, Sneh Talwar, Christopher M. Domes, Rachel M. Reilly, Ariana Paniagua, JaNell Dupree, Michael J. Weaver, Arvind G. von Keudell, Abigail E. Sagona, Samir Mehta, Derek Donegan, Annamarie Horan, Mary Dooley, Marilyn Heng, Mitchel B. Harris, David W. Lhowe, John G. Esposito, Ahmad Alnasser, Steven F. Shannon, Alesha N. Scott, Bobbi Clinch, Becky Weber, Michael J. Beltran, Michael T. Archdeacon, Henry Claude Sagi, John D. Wyrick, Theodore Toan Le, Richard T. Laughlin, Cameron G. Thomson, Kimberly Hasselfeld, Carol A. Lin, Mark S. Vrahas, Charles N. Moon, Milton T. Little, Geoffrey S. Marecek, Denice M. Dubuclet, John A. Scolaro, James R. Learned, Philip K. Lim, Susan Demas, Arya Amirhekmat, and Yan Marco Dela Cruz

Subjects
General Earth and Planetary Sciences, General Environmental Science
Published
2023
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22. Allocation of Drivers’ Visual Attention During Preliminary Uses of Automated Driving: A Wizard-of-Oz Study

Author

Jessy Barré, Aisha Sahai, and Mercedes Bueno

Subjects
Mechanical Engineering, Civil and Structural Engineering
Abstract

In this experiment, we analyzed drivers’ visual attention during their first experiences with automated driving (AD). At the beginning of the study, participants ( n = 45) received one of three AD training modules: paper, video, or practice. They then drove two sessions on a public road with a Wizard-Of-Oz vehicle, each ending with a request to intervene (RTI). The first session (forward path) included 10 min of AD with a mandatory non-driving-related task (NDRT). The second session (return path) included 10 min of AD with a nonmandatory NDRT. Control checks (number and duration of gazes) toward the road and rear-view mirrors and three self-assessment questionnaires (trust, acceptability, and technophilia) were measured during both sessions. The results indicated a decrease in road and rear-view mirror gazes over time, mainly for the practice group. Drivers with a low level of trust glanced at the road and mirrors more often than participants with a high level of trust. In addition, participants with a high level of technophilia spent less time controlling the road traffic but only during the forward path. Visual attention on the road decreased rapidly during the first minutes of AD, mainly among drivers who followed the practice training and those who had a high level of trust and were tech-savvy. We observed that participants looked at the rear-view mirrors after 10 and 14 s on average after the RTI. These results raise questions about driver situation awareness in critical situations, including the capacity to intervene in an efficient and safe way during takeover requests.

Published
2022
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25. Urgent and non-urgent takeovers during conditional automated driving on public roads: The impact of different training programmes

Author

Mercedes Bueno, Aïsha Sahaï, and Jessy Barre

Subjects
050210 logistics & transportation, Situation awareness, Notice, 05 social sciences, Applied psychology, Transportation, Workload, Training (civil), Session (web analytics), Alertness, 0502 economics and business, Automotive Engineering, Mental representation, 0501 psychology and cognitive sciences, Psychology, 050107 human factors, Applied Psychology, Motor skill, Civil and Structural Engineering
Abstract

Supplying training to drivers that teaches them about automated driving and requests to intervene may help them to build and maintain a mental representation of how automation works and thereby improve takeover performance. We aimed to investigate the effect of different types of training programmes about the functioning of automated driving on drivers’ takeover performance during real driving. Fifty-two participants were split into three groups for training sessions: paper (short notice), video (3-minute tutorial) and practice (short drive). After the training, participants experienced automated driving and both urgent and non-urgent requests to intervene in a Wizard-of-Oz vehicle on public roads. Participants’ takeover time, visual behaviour, mental workload, and flow levels during the requests to intervene were assessed. Our results indicated that in urgent circumstances, participants’ takeover response times were faster in the practice training condition compared to the other training conditions. Nevertheless, the practice training session did not present any other positive effect on drivers’ visual behaviour. This could indicate that prior training, particularly when reinforcing drivers' motor skills, improved their takeover response time at the latest motor stages rather than in the early sensory states. In addition, the analysis of in-vehicle videos revealed that participants’ attention was captured in the first place by the in-vehicle human-machine interface during the urgent request to intervene. This highlights the importance for designers to display information on the HMI in an appropriate way to optimise drivers’ situation awareness in critical situations.

Published
2021
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26. Aqueous skin antisepsis before surgical fixation of open fractures (Aqueous-PREP): a multiple-period, cluster-randomised, crossover trial

Author

Gerard P. Slobogean, Sheila Sprague, Jeffrey L. Wells, Mohit Bhandari, Anthony D. Harris, C. Daniel Mullins, Lehana Thabane, Amber Wood, Gregory J. Della Rocca, Joan N. Hebden, Kyle J. Jeray, Lucas S. Marchand, Lyndsay M. O'Hara, Robert D. Zura, Christopher Lee, Joseph T. Patterson, Michael J. Gardner, Jenna Blasman, Jonah Davies, Stephen Liang, Monica Taljaard, PJ Devereaux, Gordon Guyatt, Diane Heels-Ansdell, Debra Marvel, Jana E. Palmer, Jeff Friedrich, Nathan N. O'Hara, Frances Grissom, I. Leah Gitajn, Saam Morshed, Robert V. O'Toole, Bradley Petrisor, Franca Mossuto, Manjari G. Joshi, Jean-Claude G. D'Alleyrand, Justin Fowler, Jessica C. Rivera, Max Talbot, David Pogorzelski, Shannon Dodds, Silvia Li, Gina Del Fabbro, Olivia Paige Szasz, Sofia Bzovsky, Paula McKay, Alexandra Minea, Kevin Murphy, Andrea L. Howe, Haley K. Demyanovich, Wayne Hoskins, Michelle Medeiros, Genevieve Polk, Eric Kettering, Nirmen Mahal, Andrew Eglseder, Aaron Johnson, Christopher Langhammer, Christopher Lebrun, Jason Nascone, Raymond Pensy, Andrew Pollak, Marcus Sciadini, Yasmin Degani, Heather Phipps, Eric Hempen, Herman Johal, Bill Ristevski, Dale Williams, Matthew Denkers, Krishan Rajaratnam, Jamal Al-Asiri, Jodi L. Gallant, Kaitlyn Pusztai, Sarah MacRae, Sara Renaud, John D. Adams, Michael L. Beckish, Christopher C. Bray, Timothy R. Brown, Andrew W. Cross, Timothy Dew, Gregory K. Faucher, Richard W. Gurich Jr, David E. Lazarus, S. John Millon, M. Christian Moody, M. Jason Palmer, Scott E. Porter, Thomas M. Schaller, Michael S. Sridhar, John L. Sanders, L. Edwin Rudisill Jr, Michael J. Garitty, Andrew S. Poole, Michael L. Sims, Clark M. Walker, Robert Carlisle, Erin A. Hofer, Brandon Huggins, Michael Hunter, William Marshall, Shea B. Ray, Cory Smith, Kyle M. Altman, Erin R. Pichiotino, Julia C. Quirion, Markus F. Loeffler, Austin A. Cole, Ethan J. Maltz, Wesley Parker, T. Bennett Ramsey, Alex Burnikel, Michael Colello, Russell Stewart, Jeremy Wise, Matthew Anderson, Joshua Eskew, Benjamin Judkins, James M. Miller, Stephanie L. Tanner, Rebecca G. Snider, Christine E. Townsend, Kayla H. Pham, Abigail Martin, Emily Robertson, Emily Bray, J. Wilson Sykes, Krystina Yoder, Kelsey Conner, Harper Abbott, Roman M. Natoli, Todd O. McKinley, Walter W. Virkus, Anthony T. Sorkin, Jan P. Szatkowski, Brian H. Mullis, Yohan Jang, Luke A. Lopas, Lauren C. Hill, Courteney L. Fentz, Maricela M. Diaz, Krista Brown, Katelyn M. Garst, Emma W. Denari, Patrick Osborn, Sarah N. Pierrie, Bradley Kessler, Maria Herrera, Theodore Miclau, Meir T. Marmor, Amir Matityahu, R. Trigg McClellan, David Shearer, Paul Toogood, Anthony Ding, Jothi Murali, Ashraf El Naga, Jennifer Tangtiphaiboontana, Tigist Belaye, Eleni Berhaneselase, Dmitry Pokhvashchev, William T. Obremskey, Amir Alex Jahangir, Manish Sethi, Robert Boyce, Daniel J. Stinner, Phillip P. Mitchell, Karen Trochez, Elsa Rodriguez, Charles Pritchett, Natalie Hogan, A. Fidel Moreno, Jennifer E. Hagen, Matthew Patrick, Richard Vlasak, Thomas Krupko, Michael Talerico, Marybeth Horodyski, Marissa Pazik, Elizabeth Lossada-Soto, Joshua L. Gary, Stephen J. Warner, John W. Munz, Andrew M. Choo, Timothy S. Achor, Milton L. 'Chip' Routt, Michael Kutzler, Sterling Boutte, Ryan J. Warth, Michael J. Prayson, Indresh Venkatarayappa, Brandon Horne, Jennifer Jerele, Linda Clark, Christina Boulton, Jason Lowe, John T. Ruth, Brad Askam, Andrea Seach, Alejandro Cruz, Breanna Featherston, Robin Carlson, Iliana Romero, Isaac Zarif, Niloofar Dehghan, Michael McKee, Clifford B. Jones, Debra L. Sietsema, Alyse Williams, Tayler Dykes, Ernesto Guerra-Farfan, Jordi Tomas-Hernandez, Jordi Teixidor-Serra, Vicente Molero-Garcia, Jordi Selga-Marsa, Juan Antonio Porcel-Vazquez, Jose Vicente Andres-Peiro, Ignacio Esteban-Feliu, Nuria Vidal-Tarrason, Jordi Serracanta, Jorge Nuñez-Camarena, Maria del Mar Villar-Casares, Jaume Mestre-Torres, Pilar Lalueza-Broto, Felipe Moreira-Borim, Yaiza Garcia-Sanchez, Francesc Marcano-Fernández, Laia Martínez-Carreres, David Martí-Garín, Jorge Serrano-Sanz, Joel Sánchez-Fernández, Matsuyama Sanz-Molero, Alejandro Carballo, Xavier Pelfort, Francesc Acerboni-Flores, Anna Alavedra-Massana, Neus Anglada-Torres, Alexandre Berenguer, Jaume Cámara-Cabrera, Ariadna Caparros-García, Ferran Fillat-Gomà, Ruben Fuentes-López, Ramona Garcia-Rodriguez, Nuria Gimeno-Calavia, Marta Martínez-Álvarez, Patricia Martínez-Grau, Raúl Pellejero-García, Ona Ràfols-Perramon, Juan Manuel Peñalver, Mònica Salomó Domènech, Albert Soler-Cano, Aldo Velasco-Barrera, Christian Yela-Verdú, Mercedes Bueno-Ruiz, Estrella Sánchez-Palomino, Vito Andriola, Matilde Molina-Corbacho, Yeray Maldonado-Sotoca, Alfons Gasset-Teixidor, Jorge Blasco-Moreu, Núria Fernández-Poch, Josep Rodoreda-Puigdemasa, Arnau Verdaguer-Figuerola, Heber Enrique Cueva-Sevieri, Santiago Garcia-Gimenez, Darius G. Viskontas, Kelly L. Apostle, Dory S. Boyer, Farhad O. Moola, Bertrand H. Perey, Trevor B. Stone, H. Michael Lemke, Ella Spicer, Kyrsten Payne, Robert A. Hymes, Cary C. Schwartzbach, Jeff E. Schulman, A. Stephen Malekzadeh, Michael A. Holzman, Greg E. Gaski, Jonathan Wills, Holly Pilson, Eben A. Carroll, Jason J. Halvorson, Sharon Babcock, J. Brett Goodman, Martha B. Holden, Wendy Williams, Taylor Hill, Ariel Brotherton, Nicholas M. Romeo, Heather A. Vallier, Anna Vergon, Thomas F. Higgins, Justin M. Haller, David L. Rothberg, Zachary M. Olsen, Abby V. McGowan, Sophia Hill, Morgan K. Dauk, Patrick F. Bergin, George V. Russell, Matthew L. Graves, John Morellato, Sheketha L. McGee, Eldrin L. Bhanat, Ugur Yener, Rajinder Khanna, Priyanka Nehete, David Potter, Robert VanDemark III, Kyle Seabold, Nicholas Staudenmier, Marcus Coe, Kevin Dwyer, Devin S. Mullin, Theresa A. Chockbengboun, Peter A. DePalo Sr., Kevin Phelps, Michael Bosse, Madhav Karunakar, Laurence Kempton, Stephen Sims, Joseph Hsu, Rachel Seymour, Christine Churchill, Ada Mayfield, Juliette Sweeney, Todd Jaeblon, Robert Beer, Brent Bauer, Sean Meredith, Sneh Talwar, Christopher M. Domes, Mark J. Gage, Rachel M. Reilly, Ariana Paniagua, JaNell Dupree, Michael J. Weaver, Arvind G. von Keudell, Abigail E. Sagona, Samir Mehta, Derek Donegan, Annamarie Horan, Mary Dooley, Marilyn Heng, Mitchel B. Harris, David W. Lhowe, John G. Esposito, Ahmad Alnasser, Steven F. Shannon, Alesha N. Scott, Bobbi Clinch, Becky Weber, Michael J. Beltran, Michael T. Archdeacon, Henry Claude Sagi, John D. Wyrick, Theodore Toan Le, Richard T. Laughlin, Cameron G. Thomson, Kimberly Hasselfeld, Carol A. Lin, Mark S. Vrahas, Charles N. Moon, Milton T. Little, Geoffrey S. Marecek, Denice M. Dubuclet, John A. Scolaro, James R. Learned, Philip K. Lim, Susan Demas, Arya Amirhekmat, and Yan Marco Dela Cruz

Subjects
Adult, Male, Canada, Cross-Over Studies, Chlorhexidine, General Medicine, Antisepsis, Middle Aged, Fractures, Open, Anti-Infective Agents, Local, Humans, Surgical Wound Infection, Female, Povidone-Iodine
Abstract

Chlorhexidine skin antisepsis is frequently recommended for most surgical procedures; however, it is unclear if these recommendations should apply to surgery involving traumatic contaminated wounds where povidone-iodine has previously been preferred. We aimed to compare the effect of aqueous 10% povidone-iodine versus aqueous 4% chlorhexidine gluconate on the risk of surgical site infection in patients who required surgery for an open fracture.We conducted a multiple-period, cluster-randomised, crossover trial (Aqueous-PREP) at 14 hospitals in Canada, Spain, and the USA. Eligible patients were adults aged 18 years or older with an open extremity fracture treated with a surgical fixation implant. For inclusion, the open fracture required formal surgical debridement within 72 h of the injury. Participating sites were randomly assigned (1:1) to use either aqueous 10% povidone-iodine or aqueous 4% chlorhexidine gluconate immediately before surgical incision; sites then alternated between the study interventions every 2 months. Participants, health-care providers, and study personnel were aware of the treatment assignment due to the colour of the solutions. The outcome adjudicators and data analysts were masked to treatment allocation. The primary outcome was surgical site infection, guided by the 2017 US Centers for Disease Control and Prevention National Healthcare Safety Network reporting criteria, which included superficial incisional infection within 30 days or deep incisional or organ space infection within 90 days of surgery. The primary analyses followed the intention-to-treat principle and included all participants in the groups to which they were randomly assigned. This study is registered with ClinicalTrials.gov, NCT03385304.Between April 8, 2018, and June 8, 2021, 3619 patients were assessed for eligibility and 1683 were enrolled and randomly assigned to povidone-iodine (n=847) or chlorhexidine gluconate (n=836). The trial's adjudication committee determined that 45 participants were ineligible, leaving 1638 participants in the primary analysis, with 828 in the povidone-iodine group and 810 in the chlorhexidine gluconate group (mean age 44·9 years [SD 18·0]; 629 [38%] were female and 1009 [62%] were male). Among 1571 participants in whom the primary outcome was known, a surgical site infection occurred in 59 (7%) of 787 participants in the povidone-iodine group and 58 (7%) of 784 in the chlorhexidine gluconate group (odds ratio 1·11, 95% CI 0·74 to 1·65; p=0·61; risk difference 0·6%, 95% CI -1·4 to 3·4).For patients who require surgical fixation of an open fracture, either aqueous 10% povidone-iodine or aqueous 4% chlorhexidine gluconate can be selected for skin antisepsis on the basis of solution availability, patient contraindications, or product cost. These findings might also have implications for antisepsis of other traumatic wounds.US Department of Defense, Canadian Institutes of Health Research, McMaster University Surgical Associates, PSI Foundation.

Published
2022

27. [Caring for the caregiver: The emotional impact of the coronavirus epidemic on nurses and other health professionals]

Author

Mercedes Bueno Ferrán and Sergio Barrientos-Trigo

Subjects
Sleep Wake Disorders, Coronavirus disease 2019 (COVID-19), Health Personnel, Guidelines as Topic, Anxiety, Stress, Breathing Exercises, Article, 03 medical and health sciences, 0302 clinical medicine, Nursing, Health care, Pandemic, Burnout, Humans, 030212 general & internal medicine, Exercise, Pandemics, General Nursing, Depressive symptoms, Health professionals, Depression, SARS-CoV-2, business.industry, Coping resources, COVID-19, General Medicine, Occupational Diseases, Psychotherapy, Psychological, Emotional adjustment, Nursing Staff, Symptom Assessment, Psychology, business, COVID 19, Mindfulness, Stress, Psychological, 030217 neurology & neurosurgery, High tension
Abstract

Resumen La crisis sanitaria provocada por la pandemia del virus Covid-19 ha vuelto a destacar el papel de los profesionales sanitarios como elemento clave para su contención que sufren una alta tensión marcada por la presión asistencial y la falta de medios de protección. Ante esta tensión, resulta relevante analizar el impacto emocional en los profesionales sanitarios de la pandemia de coronavirus y los recursos de afrontamiento para disminuir o atenuar este impacto. Destacan el estrés, los trastornos del sueño y los síntomas depresivos. Se ofrecen algunas estrategias que han sido utilizados por profesionales que anteriormente han sufrido la presión del COVID-19 y les han sido de utilidad. Por último, se señalan algunas recomendaciones cuya eficacia es conocida para el manejo del impacto emocional.

Published
2021
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28. Evaluation of the impact of the Spanish Consensus Document on the approach to osteoarticular infections in Spain through the Paediatrics Osteoarticular Infections Network (RIOPED)

Author

Olga Calavia Gasaball, Matilde Bustillo Alonso, Ana Menasalvas Ruíz, Carmen Moreno, Sandra Masegosa-Casanova, Elisa Garrote, Begoña Losada Pinedo, Elena Pereira, Luis Mayol Canals, Leticia Merino Meléndez, Elena Urbaneja Rodríguez, Antonio José Conejo Fernández, Sara Pons Morales, Antonio J. Cepillo, M. Teresa Coll, Sagrario Bustabab Reyes, Isabel Vives Oñós, Marisol Camacho Lovillo, Rafael Díez Delgado, F. José Sanz Santaeufemia, Neus Rius Gordillo, Manuel Muñiz Fontán, M. José Cilleruelo Ortega, Beatriz Bravo Mancheño, Jan Ramakers, Marcelina Algar Serrano, Cristina Calvo, María Ríos Barnés, Federico Martinón-Torres, Lola Falcón Neyra, Roi Piñeiro-Pérez, Leticia Martínez Campos, Marta García Ramírez, M. Mercedes Bueno Campaña, César G. Fontecha, Lourdes García Rodríguez, Verónica Cardona, Beatriz Jiménez Montero, Rebeca Lahoz Ramo, Daniel Domenech Zarketa, Carmelo Guerrero Laleona, Jaime Carrasco Colom, Pere Soler-Palacín, Patricia Tejera Carreño, Carlos Pérez Méndez, Azucena García Martín, Rosa Roldán Molina, José Couceiro Gianzo, Natalia Cerdeira Barreiro, Carmen García-Pardos, Leonor Arranz, Agustín López López, María Méndez Hernández, Miguel Lillo Lillo, Alfredo Tagarro García, M. Jesús García-Mazarío, Rosa María Alcobendas Rueda, Elena Colino Gil, Pedro Terol Barrero, Adriana Vidal Acevedo, Berta Pujol Soler, Raquel Marín Domenech, M. José Lirola Cruz, Laura Martín-Pedraz, Daniel Clemente Garulo, Elisa Fernández-Cooke, Victoria Fumadó Pérez, Pilar Ranchal Pérez, Javier Arístegui-Fernández, Marta Illán Ramos, Belén Sevilla, Miren Oscoz Lizarbe, Jesús Saavedra-Lozano, Soledad Martínez-Regueira, Antonio Medina Claros, José Tomás Ramos, Marina González, César Gavilán Martín, Anna Canet, Carmen Vázquez Ordónez, Paula Alcañiz Rodríguez, Enrique Otheo de Tejada, M. Dolores García, M. José Muñoz Vilchez, Silvia Rodríguez-Blanco, Irene Rivero-Calle, Marta Ruiz Jiménez, Carla Monterde Pedrab, Silvia Urraca Camps, M. Concepción Mir Perelló, Valentín Pineda Solas, María Penín Antón, Inmaculada López-Molina, Esmeralda Nuñez Cuadros, Juan Salvador Vílchez, Isabel Vara Patudo, Borja Guarch Ibáñez, Susana Melendo-Pérez, and Jesús de la Cruz Moreno

Subjects
Spondylodiscitis, Infecciones osteoarticulares, Pediatrics, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Radiography, Osteomielitis, Antibiotics, RJ1-570, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Management of Technology and Innovation, medicine, Tratamiento, Blood culture, Arthrotomy, medicine.diagnostic_test, business.industry, Osteomyelitis, Diagnóstico, Retrospective cohort study, medicine.disease, Artritis séptica, Septic arthritis, business
Abstract

Introduction: In 2014 the Consensus Document produced by the Spanish Paediatric Societies (SEIP-SERPE-SEOP) was published to help in the diagnosis and treatment of osteoarticular infections (OAI). In 2015 the RIOPed was considered as a multidisciplinary national network for the investigation into OAI. The aim of this study was to assess the level of adaption to the recommendations established in the Consensus during one year of follow-up. Material and methods: A prospective, national multicentre study was carried out in 37 hospitals between September 2015 and September 2016. The study included patients >16 years-old with a diagnosis of OAI, confirmed by microbiological isolation, or probable: septic arthritis (SA) with >40,000 white cells in synovial fluid, or osteomyelitis (OM)/spondylodiscitis (SD) with a compatible imaging test. The results were compared with those obtained in a retrospective study conducted between 2008 and 2012. Results: A total of 235 cases were included, of which 131 were OM, 79 SA, 30 OA, and 15 SD. As regards the complementary tests that the Consensus considered mandatory to perform, radiography was carried out on 87.8% of the cases, a blood culture on 91.6%, and culture of the synovial fluid in 99% of SA. A magnetic resonance (MR) was performed on 71% of the OM cases. The choice of intravenous empirical antibiotic treatment was adapted to the recommendations in 65.1% of cases, and in 62.3% for the oral treatment. Surgery was performed in 36.8% of SA cases (85.7% arthrotomy), with a significant decrease compared to the retrospective study (P = .014). Only 58.5% of cases followed the recommendations on the duration of the treatment; however, a lower duration of intravenous treatment was observed. Conclusions: In general, the level of adaptation to the recommendations that were set by the Expert Group, is good for the complementary tests, and acceptable as regards the choice of antibiotic treatment, although inadequate in almost 40% of cases. A decrease in hospital stay was achieved. Resumen: Introducción: En 2014 se publicó el Documento de Consenso desarrollado por SEIP-SERPE-SEOP para el diagnóstico y el tratamiento de las infecciones osteoarticulares (IOA). En 2015 se constituyó RIOPed como red nacional multidisciplinar para la investigación en IOA. El objetivo del estudio ha sido valorar el grado de adecuación a las recomendaciones establecidas en el consenso durante un año de seguimiento. Material y métodos: Estudio prospectivo multicéntrico nacional realizado entre septiembre de 2015 y septiembre de 2016 en 37 hospitales con inclusión de pacientes menores de 16 años diagnosticados de IOA, confirmada mediante aislamiento microbiológico, o probable: artritis séptica (AS) con >40.000 leucocitos en líquido sinovial u osteomielitis (OM)/osteoartritis (OA)/espondilodiscitis (ED) con prueba de imagen compatible. Los resultados se compararon con los obtenidos en el estudio retrospectivo realizado entre 2008 y 2012. Resultados: Se incluyeron 255 casos: 131 OM, 79 AS, 30 OA y 15 ED. Respecto a las pruebas complementarias que el consenso consideró de obligada realización, la radiografía se llevó a cabo en el 87,8% de los casos, el hemocultivo en el 91,6% y el cultivo de líquido sinovial en el 99% de AS. Se realizó RM en el 71% de las OM. La elección del tratamiento antibiótico intravenoso empírico se adecuó a las recomendaciones en el 65,1% de los casos, y en el 62,3% para el tratamiento oral. Se llevó a cabo cirugía en el 36,8% de las AS (85,7% artrotomía), con un descenso significativo respecto al estudio retrospectivo (P = ,014). Solo el 58,5% de casos se ajustaron a las recomendaciones de duración del tratamiento; sin embargo, se comprobó una menor duración del tratamiento intravenoso. Conclusiones: En general, el grado de adecuación a las recomendaciones que marcaron el grupo de expertos es bueno para las pruebas complementarias y aceptable respecto a la elección del tratamiento antibiótico, aun detectándose casi un 40% de inadecuación. Se ha conseguido un descenso de la estancia hospitalaria.

Published
2020

29. From manual to automated driving: how does trust evolve?

Author

Jordan Navarro, J. B. Manchon, and Mercedes Bueno

Subjects
ComputingMilieux_GENERAL, 050210 logistics & transportation, Computer science, 0502 economics and business, 05 social sciences, In vehicle, Driving simulation, 0501 psychology and cognitive sciences, Human Factors and Ergonomics, Industrial engineering, Driving automation, 050107 human factors
Abstract

Technological innovations have made driving automation closer and closer to reality. Despite this, the adoption of highly automated driving by the public is not guaranteed yet, and trust in vehicle...

Published
2020
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30. Reducing health inequalities among most disadvantaged type 2 diabetes patients: A cross-sectional exploratory pilot study

Author

Ana María Barrios Quinta, Rubén Morilla Romero de la Osa, Mercedes Bueno Ferrán, and Universidad de Sevilla. Departamento de Enfermería

Subjects
Male, diabetes mellitus type 2, Pilot Projects, Health Status Disparities, Middle Aged, primary health care, Social determinants of health, Diabetes mellitus type 2, Cross-Sectional Studies, Diabetes Mellitus, Type 2, social determinants of health, Humans, Health status disparities, Female, General Nursing, Primary health care, Aged, Retrospective Studies
Abstract

[Background] Demographic changes and the increased chronical diseases burden are global challenges that cannot go unnoticed by healthcare systems, which must be organized without losing sight of the increasing influence of social determinants., [Aim] To evaluate the results of a primary care program implemented to reduce health inequalities associated with social determinants in patients with type 2 diabetes., [Method] An exploratory pilot retrospective cross-sectional study that includes secondary data of 404 nonrandomized patients belonging to socially depressed areas and conventional areas. Descriptive, bivariate, and multivariate analyses were performed., [Results] The age of the subjects included in the study was 66.80 ± 9.7 years with a proportion of 56.7% men. Proportions of patients from socially depressed areas and adherence to the Nursing Follow-up Program were around 33% and 60%, respectively. The obesity rate was 51%, percentage of patients with HbA1c, [Conclusions] The program has proven to be efficient in equating the health outcomes related with cardiovascular risk of patients from both types of areas. Well-directed health policies could bring primary care systems closer to sustainable development goals through the reduction of health disparities that affect socially vulnerable groups., [Clinical relevance] To introduce a risk strategy and to adopt a family approach, contemplating the sociocultural and educational differences that diversely affect men and women in their health status has proven to be useful in reducing health disparities due to social determinants in patients with type 2 diabetes.

Published
2022

31. Why do they trust it? Determinants of the initial Trust in Automated Driving

Author

J. B. Manchon, Romane Beaufort, Mercedes Bueno, and Jordan Navarro

Abstract

Because driving automation is quickly increasing, humans’ relation to automated driving evolves accordingly. Trust in automated driving has been shown to strongly correlate with drivers’ acceptance of such systems. Nonetheless, there is currently a lack of specific questionnaires to assess drivers’ level of trust in Highly Automated Driving (HAD). Moreover, little is known about which factors determine trust before any interaction with HAD systems. Theoretical trust in automation models propose several factors to explain how trust builds before and during interactions with automation. Using 844 answers collected through an online survey, this paper aims to propose a new scale designed to evaluate initial trust in automated driving. Moreover, we also measure other factors linked to drivers’ initial level of trust in HAD by operationalizing the trust components proposed by Hoff and Bashir (2015)’s theoretical trust model. In order to better describe what determines trust in HAD, a linear model based on the collected data is proposed. The model not only weights the factors determining trust but is also able to predict the level of trust considering these factors.

Published
2022
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32. Anales de Pediatría: We take over

Author

Alejandro Ávila Álvarez, Víctor Manuel Navas López, Mercedes Bueno Campaña, Josep Vicent Balaguer-Martínez, and Montserrat Antón Gamero

Subjects
Publishing, Bibliometrics, Management of Technology and Innovation, Take over, Psychology, Pediatrics, RJ1-570
Published
2021

33. A User-Centered Approach to Adapt the Human-Machine Cooperation Strategy in Autonomous Driving

Author

Annie Pauzié, Mercedes Bueno, Arnaud Koustanaï, Franck Mars, Stéphanie Coeugnet, Hélène Tattegrain, Chouki Sentouh, Jean-Christophe Popieul, VEhicule DEcarboné et COmmuniquant et sa Mobilité (VeDeCom), Laboratoire des Sciences du Numérique de Nantes (LS2N), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-École Centrale de Nantes (ECN)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Laboratoire d'Automatique, de Mécanique et d'Informatique industrielles et Humaines - UMR 8201 (LAMIH), Centre National de la Recherche Scientifique (CNRS)-Université Polytechnique Hauts-de-France (UPHF)-INSA Institut National des Sciences Appliquées Hauts-de-France (INSA Hauts-De-France), Laboratoire d'Accidentologie de Biomécanique et d'Etude du Comportement Humain, RENAULT, Laboratoire Ergonomie et Sciences Cognitives pour les Transports (TS2-LESCOT ), Université Gustave Eiffel, ANR-16-CE22-0007,AutoConduct,Adaptation de la stratégie d'automatisation des véhicules autonomes (niveaux 3-4) aux besoins et à l'état des conducteurs en conditions réelles(2016), IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-École Centrale de Nantes (ECN)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-École Centrale de Nantes (ECN)-Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), and Université de Nantes (UN)-Université de Nantes (UN)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique)

Subjects
DRIVER MONITORING, 050210 logistics & transportation, VEHICULE, Human machine cooperation, Computer science, media_common.quotation_subject, 05 social sciences, [SHS.PSY]Humanities and Social Sciences/Psychology, ADAPTIVE SYSTEM, Human–computer interaction, Adaptive system, 0502 economics and business, CONDUITE DU VEHICULE, 0501 psychology and cognitive sciences, Quality (business), VEHICULE AUTONOME, AIDE A LA CONDUITE, AUTONOMOUS DRIVING, CONTROLE, 050107 human factors, media_common, HMI
Abstract

21st Congress of the International Ergonomics Association (IEA 2021), VANCOUVER, CANADA, 14-/06/2021 - 18/06/2021; International audience; Using an integrative user-centered approach, the research project aimed at designing and assessing an adaptive HMI to improve the safety and the quality of the take-over in a level-3 automated vehicle. Future autonomous driving users confirmed the need for the monitoring systems to improve safety as long as they are simple and not intrusive. They request specific information to understand and initiate appropriated actions in case of a critical situation. However, to avoid overloading and detri-mental effects, it is important that the system limits the amount of infor-mation at the right moment.

Published
2021
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34. Riesgo de COVID-19 en españoles y migrantes de distintas zonas del mundo residentes en España en la primera oleada de la enfermedad

Author

Juan Emilio Losa, e investigadores Covid Alcorcón, Gil Rodríguez-Caravaca, M. Mercedes Izquierdo, Mercedes Bueno-Campaña, Rosa María Fariña, Carmen Noguera, Carlos Guijarro, Margarita Mosquera, V. Meléndez, Montserrat Pérez-Encinas, I. Sastre, Isabel Galán, Aurora Fabero, Elia Pérez-Fernández, Gregorio Bonilla Zafra, Alejandro Algora, Virgilio Castilla, Maria José Goyanes, Isabel González-Anglada, Maria Luisa Casas, José Francisco Valverde, M. Velasco, M. E. Renilla, Susana Lorenzo, B. González-Piñeiro, Juan Carlos Alonso-Punter, and Ana Isabel Díaz-Cuasante

Subjects
business.industry, Original, Epidemiology, Ethnic minorities, Cohort, COVID-19, General Medicine, Riesgo relativo, Migrants, Relative risk, 03 medical and health sciences, Cohortes, 0302 clinical medicine, Medicine, Epidemiología, Minorías étnicas, 030212 general & internal medicine, business, Migrantes, Humanities
Abstract

Introducción y objetivos Existen pocos estudios sobre el potencial papel de los orígenes raciales/étnicos en el riesgo de infección de COVID-19, particularmente en Europa. Evaluamos el riesgo de COVID-19 entre los migrantes de diferentes zonas del mundo en un contexto de acceso universal gratuito a la atención médica. Material y métodos Realizamos un análisis de cohortes poblacional de la incidencia acumulada de COVID-19 confirmada mediante PCR entre los residentes adultos en Alcorcón (España) en la primera oleada de la enfermedad hasta el 25 de abril de 2020. Resultados La incidencia acumulada bruta entre los migrantes (n = 20.419) fue mayor que entre los españoles (n = 131.599): 8,81 y 6,51 por cada 1.000 habitantes, respectivamente (p

Published
2021
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35. How drowsiness and distraction can interfere with take-over performance: A systematic and meta-analysis review

Author

Gaëtan Merlhiot and Mercedes Bueno

Subjects
Automobile Driving, Public Health, Environmental and Occupational Health, Accidents, Traffic, Reaction Time, Humans, Human Factors and Ergonomics, Wakefulness, Safety, Risk, Reliability and Quality
Abstract

Drowsiness and distraction are major factors of road crashes and responsible of35% of road fatalities. Automated driving could solve or minimize their impact, yet it is also in itself a way to promote them. Previous literature reviews and meta-analysis regarding take-overs during automated driving primarily focused on distraction rather than drowsiness. We thus present a systematic and meta-analysis literature review focused on the effect of distraction and drowsiness on take-over performance. From an initial selection of 1896 articles from databases, we obtained by applying systematic review methodology a total of 58 articles with 42 articles dedicated to distraction and 17 articles related to drowsiness. According to our analysis, we demonstrated that distraction and drowsiness increased the take-over request reaction time (TOR-RT), which could also lead to a reduction of the quality of take-overs. In addition, this longer reaction time was even more important in the case of handheld non-driving related tasks, which is important to consider as phone use is among the most frequent tasks done during automated driving. On a more methodological aspect, we also demonstrated that take-over time budget had a significant effect on TOR-RT. However, it is difficult to estimate to what extend distraction and drowsiness could impact the take-over quality, even if several elements supported safety issues. We underpinned several limits of the current methodologies applied in the study of distraction and drowsiness such as (i) the lack of additional measures related to the take-over quality (e.g., accelerations, collision rate), (ii) the many different methodologies applied to the determination of the TOR-RT (e.g., deactivation by the steering wheel, pedals, button), (iii) the high frequency of take-over requests which can lead to habituation effects, (iv) the lack of control conditions, (v) the fact that the level of drowsiness was relatively low in most studies. We thus highlighted recommendations for a better estimation of the effect of distraction and drowsiness on take-over performance. Further studies should adopt more standardized measures of TOR-RT and additional take-over quality measures, try minimizing the number of take-over requests, and carefully consider the time budget available for the use case since it influences the TOR-RT. Regarding distraction, researchers should consider the impact of tasks requiring handholding items. Concerning drowsiness, further protocols should consider the non-linearity of drowsiness and presence of micro sleeps and favor take-over requests based on drowsiness level protocols rather than on fixed duration protocols.

Published
2021

36. Patient and stakeholder engagement learnings: PREP-IT as a case study

Author

Michelle Medeiros, T Rosie Love, Gerard P. Slobogean, Sheila Sprague, Eleanor M. Perfetto, Nathan N. O'Hara, C. Daniel Mullins, Jeffrey Wells, Mohit Bhandari, Jean-Claude D'alleyrand, Anthony Harris, Daniel C. Mullins, Lehana Thabane, Amber Wood, Gregory J. Della Rocca, Joan Hebden, Kyle J. Jeray, Lucas Marchand, Lyndsay M. O'Hara, Robert Zura, Michael J. Gardner, Jenna Blasman, Jonah Davies, Stephen Liang, Monica Taljaard, PJ Devereaux, Gordon H. Guyatt, Dianne Heels-Ansdell, Debra Marvel, Jana Palmer, Jeff Friedrich, Nathan O'Hara, Frances Grissom, Leah Gitajn, Saam Morshed, Robert O'Toole, Bradley A. Petrisor, Megan Camara, Franca Mossuto, Manjari G. Joshi, Justin Fowler, Jessica Rivera, Max Talbot, Shannon Dodds, Alisha Garibaldi, Silvia Li, Uyen Nguyen, David Pogorzelski, Alejandra Rojas, Taryn Scott, Gina Del Fabbro, Olivia Page Szasz, Paula McKay, Andrea Howe, Joshua Rudnicki, Haley Demyanovich, Kelly Little, Adam Boissonneault, Michellic Medeiros, Eric Kettering, Diamond Hale, Nirmen Mahal, Andrew Eglseder, Aaron Johnson, Christopher Langhammer, Christopher Lebrun, Theodore Manson, Jason Nascone, Ebrahim Paryavi, Raymond Pensy, Andrew Pollack, Marcus Sciadini, Yasmin Degani, Katherine Joseph, Lucas S. Marchand, Heather Phipps, Eric Hempen, Herman Johal, Bill Risteyski, Dale Williams, Matthew Denkers, Krishan Rajaratnam, Jamal Al-Asiri, Jordan Leonard, Francesc A. Marcano-Fernández, Jodi Gallant, Federico Persico, Marko Gjorgjievski, Annie George, Sarah M. McGaugh, Kaitlyn Pusztai, Sarah Piekarski, Mavis Lyons, Julia Gennaccaro, Roman M. Natoli, Greg E. Gaski, Todd O. McKinley, Walter W. Virkus, Anthony T. Sorkin, Jan P. Szatkowski, Joseph R. Baele, Brian H. Mullis, Yohan Jang, Luke A. Lopas, Lauren C. Hill, Andrea Hudgins, Courteney L. Fentz, Maricela M. Diaz, Katelyn M. Garst, Emma W. Denari, Patrick Osborn, Sarah Pierrie, Eric Martinez, Joseph Kimmel, Maria Herrera, John D. Adams, Michael Beckish, Christopher Bray, Timothy R. Brown, Andrew W. Cross, Timothy Dew, Gregory Faucher, Richard W. Gurich Jr, David E. Lazarus, S. John Millon, M. Jason Palmer, Scott E. Porter, Thomas M. Schaller, Michael S. Sridhar, John L. Sanders, Edwin L. Rudisill Jr, Michael J. Garitty, Andrew S. Poole, Michael L. Sims, Clark M. Walker, Robert M. Carlisle II, Erin Adams Hofer, Brandon S. Huggins, Michael D. Hunter, William A. Marshall, Shea Bielby Ray, Cory D. Smith, Kyle M. Altman, Julia C. Bedard, Markus F. Loeffler, Erin R. Pichiotino, Austin A. Cole, Ethan J. Maltz, Wesley Parker, T. Bennett Ramsey, Alex Burnikel, Michael Colello, Russell Stewart, Jeremy Wise, M. Christian Moody, Matthew Anderson, Joshua Eskew, Benjamin Judkins, James M. Miller, Stephanie L. Tanner, Rebecca G. Snider, Christine E. Townsend, Kayla H. Pham, Abigail Martin, Emily Robertson, John Wilson Sykes, Theodore Miclau, Utku Kandemir, Meir Marmor, Amir Matityahu, R. Trigg McClellan, Eric Meinberg, David Shearer, Paul Toogood, Anthony Ding, Erin Donohue, Jothi Murali, Ashraf El Naga, Jennifer Tangtiphaiboontana, Tigist Belaye, Eleni Berhaneselase, Alexandra Paul, Kartik Garg, Dmitry Pokhvashchev, Joshua L. Gary, Stephen J. Warner, John W. Munz, Andrew M. Choo, Timothy Achor, Milton L. \\'Chip\\' Routt, Mayank Rao, Guillermo Pechero, Adam Miller, Michael Kutzler, Sterling Boutte, Ryan J. Warth, Jennifer E. Hagen, Matthew Patrick, Richard Vlasak, Thomas Krupko, Kalia Sadasivan, Michael Talerico, Marybeth Horodyski, Chris Koenig, Daniel Bailey, Daniel Wentworth, Chi Van, Justin Schwartz, Marissa Pazik, Elizabeth Lossada-Soto, Niloofar Dehghan, Clifford B. Jones, J. Tracy Watson, Michael McKee, Ammar Karim, Debra L. Sietsema, Alyse William, Tayler Dykes, William T. Obremskey, Amir Alex Jahangir, Manish Sethi, Robert Boyce, Daniel J. Stinner, Phillip Mitchell, Karen Trochez, Andres Rodriguez, Vamshi Gajari, Elsa Rodriguez, Chris Pritchett, Natalie Hogan, Fidel A. Moreno, Christina Boulton, Jason Lowe, Jason Wild, John T. Ruth, Michel Taylor, Brad Askam, Andrea Seach, Sabina Saeed, Hunter Culbert, Alejandro Crus, Thomas Knapp, Colin Hurkett, Maya Lowney, Breanna Featherston, Robin Carlson, Iliana Romero, Isaac Zarif, Michael Prayson, Indresh Venkatarayappa, Brandon Horne, Jennifer Jerele, Linda Clark, Francesc Marcano-Fernández, Montsant Jornet-Gibert, Laia Martínez-Carreres, David Martí-Garín, Jorge Serrano-Sanz, Joel Sánchez-Fernández, Matsuyama Sanz-Molero, Alejandro Carballo, Xavier Pelfort, Francesc Acerboni-Flores, Anna Alavedra-Massana, Neus Anglada-Torres, Alexandre Berenguer, Jaume Cámara-Cabrera, Ariadna Caparros-García, Ferran Fillat-Gomà, Ruben Fuentes-López, Ramona Garcia-Rodriguez, Nuria Gimeno-Clavia, Guillem Graells-Alonso, Marta Martínez-álvarez, Patricia Martínez-Grau, Raúl Pellejero-García, Ona Ràfols-Perramon, Juan Manuel Peñalver, Mònica Salomò Domènech, Albert Soler-Cano, Aldo Velasco-Barrera, Christian Yela-Verdú, Mercedes Bueno-Ruiz, Estrella Sánchez-Palomino, Vito Andriola, Matilde Molina-Corbacho, Yeray Maldonado-Sotoca, Alfons Gasset-Teixidor, Jorge Blasco-Moreu, Núria Fernández-Poch, Josep Rodoreda-Puigdemasa, Arnau Verdaguer-Figuerola, Heber Enrique Cueva-Sevieri, Santiago Garcia-Gimenez, Ernesto Guerra-Farfán, Jordi Tomas-Hernandez, Jordi Teixidor-Serra, Vicente Molero-Garcia, Jordi Selga-Marsa, Juan Antonio Porcel-Vazquez, Jose Vicente Andres-Peiro, Joan Minguell-Monyart, Jorge Nuñez-Camarena, Maria del Mar Villar-Casares, Jaume Mestre-Torres, Pilar Lalueza-Broto, Felipe Moreira-Borim, Yaiza García, Nicholas M. Romeo, Heather A. Vallier, Mary A. Breslin, Joanne Fraifogl, Eleanor S. Wilson, Leanne K Wadenpfuhl, Paul G. Halliday, Isabella Heimke, Darius G. Viskontas, Kelly L. Apostle, Dory S. Boyer, Farhad O. Moola, Bertrand H. Perey, Trevor B. Stone, H. Michael Lemke, Mauri Zomar, Ella Spicer, Chen \\'Brenda\\' Fan, Kyrsten Payne, Kevin Phelps, Michael Bosse, Madhav Karunakar, Laurence Kempton, Stephen Sims, Joseph Hsu, Rachel Seymour, Christine Churchill, Claire Bartel, Robert Miles Mayberry, Maggie Brownrigg, Cara Girardi, Ada Mayfield, Juliette Sweeney, Hannah Pollock, Robert A. Hymes, Cary C. Schwartzbach, Jeff E. Schulman, A. Stephen Malekzadeh, Michael A. Holzman, Jonathan Wills, Lolita Ramsey, James S. Ahn, Farhanaz Panjshiri, Sharmistha Das, Antoinisha D. English, Sharon M. Haaser, Jaslynn A.N. Cuff, Holly Pilson, Eben A. Carroll, Jason J. Halvorson, Sharon Babcock, J. Brett Goodman, Martha B. Holden, Debra Bullard, Wendy Williams, Taylor Hill, Ariel Brotherton, Thomas F. Higgins, Justin M. Haller, David L. Rothberg, Ashley Neese, Mark Russell, Zachary M. Olsen, Abby V. McGowan, Sophia Hill, Marcus Coe, Kevin Dwyer, Devin S. Mullin, Clifford A Reily, Peter DePalo, Amy E. Hall, Rebecca E. Dabrowski, Theresa A. Chockbengboun, Marilyn Heng, Mitchel B. Harris, R. Malcolm Smith, David W. Lhowe, John Esposito, Mira Bansal, Michael McTague, Ahmad Alnasser, Patrick F. Bergin, George V. Russell, Matthew L. Graves, John Morellato, Heather K. Champion, Leslie N. Johnson, Skeketha L. McGee, Eldrin L. Bhanat, Josny Thimothee, Jackie Serrano, Samir Mehta, Derek Donegan, Jaimo Ahn, Annamarie Horan, Mary Dooley, Ashley Kuczinski, Ashley Iwu, David Potter, Robert VanDemark II, Branden Pfaff, Troy Hollinsworth, Kristi Atkins, Michael J. Weaver, Arvind G. von Keudel, Michael F. McTague, Elizabeth M. Allen, Abigail E. Sagona, Todd Jaeblon, Robert Beer, Brent Bauer, Sean Meredith, Autumn Stone, Mark J. Gage, Rachel M. Reilly, Cindy Sparrow, Ariana Paniagua, Christopher M. Domes, Kristina P. Johnson, Steven F. Shannon, Alesha N. Scott, Bobbi Clinch, Carol A. Lin, Mark S. Vrahas, Charles N. Moon, Geoffrey S. Marecek, Denice Dubuclet, John A. Scolaro, James R. Learned, Philip K. Lim, Susan Demas, Michael J. Beltran, Michael T. Archdeacon, Henry Claude Sagi, John D. Wyrick, Theodore Toan Le, Richard T. Laughlin, and Cameron G. Thomson

Subjects
Patient Outcome Assessment, Medical education, business.industry, Stakeholder Participation, Health Policy, Patient-Centered Care, Stakeholder engagement, Medicine, Humans, Multi stakeholder, business, Patient centered
Published
2021

37. Anales de Pediatría: tomamos el relevo

Author

Víctor Manuel Navas López, Alejandro Ávila Álvarez, Montserrat Antón Gamero, Mercedes Bueno Campaña, and Josep Vicent Balaguer-Martínez

Subjects
Pediatrics, Perinatology and Child Health, Psychology, Pediatrics, RJ1-570
Published
2021

38. Ventricular Repolarization Parameters and Coronary Involvement in Kawasaki Disease

Author

Ana Barrios-Tascón, Masaru Miura, Sara Domínguez-Rodríguez, Elisa Fernández-Cooke, Georgia Sarquella-Brugada, Alfredo Tagarro, Elisa Fernandez-Cooke, Cristina Calvo, Judith Sánchez-Manubens, Jordi Antón, Javier Aracil Santos, Esmeralda Nuñez Cuadros, Maria Luisa Navarro Gómez, David Moreno Pérez, María Martín Cantero Pérez, Esmeralda Nuñez Cuadros Pérez, Begoña Carazo Gallego Pérez, Fernando Sánchez García, Marisol Camacho Lovillo, Renata Marqués, Olaf Neth Laura, Fernández Silveira, Miguel Sánchez Forte, Ángeles Ortega Montes, Leticia Isabel Martínez Campos, Beatriz Bravo Mancheño, Margarita Camacho, Antonio F. Medina Claros, Carlos Salido, María Torres Rico, Beatriz Ruiz Saez, Elena Fernadez de la Puebla Lechuga, Ma José Lirola Cruz, Kety Maya Carrasco, Moisés Rodríguez González, Enrique Blanca Jover, José Uberos Fernández, María Mercedes Ibáñez Alcalde, Miguel Lafuente Hidalgo, Lorenzo Jiménez Montañés, Matilde Bustillo Alonso, Ariadna Ayerza Casas, Bárbara Montes Zapico, Carlos Pérez Méndez, Javier Fernández Aracama, Lucía Rodríguez, María Aleida Ibáñez Fernández, Sandra Navarro Campo, Silvia Escribà Bori, María Concepción Mir Perelló, Ma Ángeles de la Fuente Sánchez, Patricia Aparicio García, Carlos Briales, Joaquín Castilla Crespí, María Elena Colino Gil, Nerea Delgado Cabrera, Ana Bello Naranjo, Jesús Poch Páez, Moneyba García Yáñez, Montse González García, Maite Viadero, Beatriz Jiménez Montero, Olga Domínguez García, Begoña Losada Pinedo, Gema Iñigo Martín, Lucía María Escribano Gómez, Antonio Cepillo, Miguel Lillo Lillo, María Isabel Buedo, Laura del Rey, Elena Urbaneja Rodríguez, Sara Rellán Rodríguez, Teresa Cantero, Beatriz Plata Izquierdo, Luisa García-Cuenllas Álvarez, Ignacio Oulego Erroz, Elena Pérez Santaolalla, Carlos Alcalde Martín, Fernando Centeno Malfaz, Elena Pérez Gutiérrez, Ma Soledad Jiménez Casso, Fredy Prada, Rosa Bou, Estibaliz Iglesias, Joan Calzada, Olga Calavia Garsaball, Marc Tobeña Rue, Gemma Giralt García, Zulema Lobato, Neus Rius Gordillo, Montserrat Pascual Torres, María Méndez Hernández, Lourdes García, Sergio Flores Villar, Silvia Yevenes Ruiz, Laura Minguell Domingo, Anna Ballester, Ana Miralles, Berta Pujol Soler, Anton Foguet Vidal, Pere Sala Castellví, Angelita Serrano Aguiar, José Manuel Siurana Rodríguez, Anna Sangorrin Iranzo, Roser Álvarez Pérez, Paula Ribes Cajas, Pere Genaró i Jornet, Ana Grande Tejada, Cristina Zarallo, Federico Martinón-Torres, Irene Rivero Calle, Antonio Justicia Grande, María López Sousa, Alejandro Souto Vilas, Bernardo López Abel, Elisa de Miguel Esteban, Bibiana Riaño Méndez, Daniel Blázquez, Pablo Rojo Conejo, Carlos Grasa Lozano, Belén Toral, Leticia Albert De la Torre, Jaime de Inocencio, Mar Santos, Rafael Díaz-Delgado de la Peña, Paz Collado Ramos, Teresa Raga, Libertad Latorre, Sara Guillén, Ignacio Callejas Caballero, Luis Manuel Prieto Tato, María Fernanda Guzmán Monagas, Isabel Jiménez López, Sandra Villagrá, Viviana Arreo, Roi Piñeiro Pérez, María de la Parte, Amalia Tamariz-Martes, Marta Llorente Romano, Maria Belén Hernández Rupérez, Henar Rojo Sombrero, Estefanía García Cerro, Irene Maté Cano, Marta Villares Alonso, Marta Pilar Osuna Marco, Julia Jensen Veron, Cristina Zarallo Reales, María Dolores Rodríguez Mesa, Santiago Rueda Esteban, José Tomás Ramos Amador, Cristina González Menchén, Ana Belén Jiménez Jiménez, Pilar Galán, Dolores Pérez Campos, Ma Mercedes Bueno, David Crespo Marcos, Enrique Otheo de Tejada Barásoain, Walter Alberto Sifuentes Giraldo, María Luz Gámir Gámir, María José Cilleruelo Ortega, Agustín López López, Cristina Sánchez Vaquerizo, Ana Isabel Usano Carrasco, Ester Moreno Gómez, Olga Carvajal del Castillo, Beatriz Del Pozo Menéndez, Katie Badillo Navarro, Fernando Baquero, Lucía Deiros Bronte, Pablo Fernández Fraga, Nieves Domínguez, Beatriz Mercader Rodríguez, Francisco Castro García, Águeda Herrera Chamorro, Paula Alcañiz Rodríguez, Moisés Sorlí García, María Concepción Rex Nicolás, Elena Vera Romero, Patricia Martínez Olorón, Beatriz Rocandio Cilveti, Amaia Berridi, Laura Santos-Díez Vázquez, Olaia Fernández, Inmaculada Calvo, Belén Fernández Tudela, Manuel Oltra Benavent, Marta Dapena Archilés, Franciasco Sanchez Ferrer, César Gavilán, Ignacio Izquierdo Fos, María Isabel Serrano Robles, Yolanda Herranz Sánchez, Enrique Villalobos Pinto, Daniel Clemente Garulo, Stella Pie, Manuel Marrero Calvo, and José María Olmos García

Subjects
Male, medicine.medical_specialty, Ventricular Repolarization, Heart Diseases, Heart Ventricles, Enfermedad cardiovascular, Coronary disease, Mucocutaneous Lymph Node Syndrome, QT interval, 03 medical and health sciences, Recovery period, Electrocardiography, 0302 clinical medicine, Heart Conduction System, 030225 pediatrics, Internal medicine, medicine, Humans, In patient, 030212 general & internal medicine, Enfermedad coronaria, business.industry, Pediatría, Infant, Reproducibility of Results, medicine.disease, Increased risk, Cross-Sectional Studies, Síndrome mucocutáneo linfonodular, Child, Preschool, Pediatrics, Perinatology and Child Health, Cardiology, Kawasaki disease, Female, business
Abstract

Objectives: To evaluate electrocardiogram markers to predict coronary involvement in patients with Kawasaki disease by assessing measures of ventricular repolarization parameters on the 12-lead electrocardiogram. Study design: This cross-sectional study included 180 Spanish and Japanese patients ≤14 years of age with Kawasaki disease, with or without coronary involvement, from 2011 to 2016. We manually measured the Tp-Te/QT ratio and QTc interval (with Bazett's formula) in 12-lead electrocardiogram in the acute and recovery period and explored their potential association with coronary involvement. Results: No association was found between Tp-Te/QT ratio obtained manually in V5 and V6 leads and coronary involvement in the acute (V5:0.25 [IQR, 0.21-0.27] vs 0.25 [IQR, 0.20-0.27], P = .80; V6:0.24 [IQR, 0.21-0.27] vs 0.25 [IQR, 0.20-0.27], P = .86) or the recovery (V5: 0.23 [IQR, 0.20-0.25] vs 0.23 [IQR, 0.19-0.25], P = .68; V6: 0.23 [IQR, 0.20-0.25] vs 0.23 [IQR, 0.17-0.25], P = .50) period. By contrast, QTc in V5 and V6 was significantly lower in patients with Kawasaki disease and coronary involvement in the acute period (V5: 378 ms [IQR, 364-395 ms] vs 390 ms [IQR, 371-411 ms], P = .04; V6: 377 ms [IQR, 364-392 ms] vs 390 ms [IQR, 371-410 ms], P = .01). A QTc interval of

Published
2021

39. The Nursing Stress Scale-Spanish Version: An Update to Its Psychometric Properties and Validation of a Short-form Version in Acute Care Hospital Settings

Author

Sergio Barrientos-Trigo, Bárbara Badanta, Sara Bermúdez-García, Ana María Porcel-Gálvez, Mercedes Bueno-Ferrán, Elena Fernández-García, [Porcel-Gálvez,AM, Barrientos-Trigo,S, Fernández-García,E, Bueno-Ferrán,M, Badanta,B] Faculty of Nursing, Physiotherapy and Podiatry, University of Seville, Seville, Spain. [Porcel-Gálvez,AM, Fernández-García,E, Bueno-Ferrán,M, Badanta,B] Research Group under the Andalusian Research, Development and Innovation Scheme CTS-1019 Complex Care, Chronic and Health Outcomes, Instituto de Biomedicina de Sevilla (IBIS), Seville, Spain. [Bermúdez-García,S] Hospital Vithas Sevilla, Castilleja de la Cuesta, Seville, Spain. [Bueno-Ferrán,M] Hospital Virgen del Rocío, Seville, Spain., This research was funded by the Health Ministry of the Andalusian Regional Government, grant number (PI-0045/2016)., Universidad de Sevilla. Departamento de Enfermería, and Universidad de Sevilla. CTS-1050: Cuidados Complejos, Cronicidad y Resultados en Salud

Subjects
Questionnaires, Male, Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Data Collection::Questionnaires [Medical Subject Headings], Health, Toxicology and Mutagenesis, psychometric assessment, lcsh:Medicine, Nursing Staff, Hospital, Personal de enfermería, Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings], 0302 clinical medicine, Acute care, assessment tools, Surveys and Questionnaires, Validation, Psychiatry and Psychology::Behavior and Behavior Mechanisms::Behavior::Behavioral Symptoms::Stress, Psychological [Medical Subject Headings], Nursing staf, 030212 general & internal medicine, Nursing staff, hospital, Reliability (statistics), Persons::Persons::Occupational Groups::Health Personnel::Nurses [Medical Subject Headings], Health Care::Health Care Facilities, Manpower, and Services::Health Facilities::Hospitals [Medical Subject Headings], validation, 030504 nursing, Psychometric assessment, Confirmatory factor analysis, Exploratory factor analysis, Hospitals, Health Care::Health Care Facilities, Manpower, and Services::Health Personnel::Nursing Staff::Nursing Staff, Hospital [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings], Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Reproducibility of Results [Medical Subject Headings], Assessment tools, Job satisfaction, Female, 0305 other medical science, Psychology, Estrés laboral, medicine.medical_specialty, Condiciones de trabajo, Psychometrics, instrument development, Working conditions, Check Tags::Male [Medical Subject Headings], Article, Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Psychometrics [Medical Subject Headings], Hospital, 03 medical and health sciences, Nursing, Criterion validity, medicine, Humans, nursing staff, working conditions, lcsh:R, Stressor, Public Health, Environmental and Occupational Health, Reproducibility of Results, Occupational stress, questionnaires, Cross-Sectional Studies, Instrument development, Check Tags::Female [Medical Subject Headings], occupational stress, Stress, Psychological
Abstract

Stressful working conditions are correlated with a negative impact on the well-being of nurses, job satisfaction, quality of patient care and the health of the staff. The Nursing Stress Scale (NSS) has been shown to be a valid and reliable instrument to assess occupational stressors among nurses. This study updates the psychometric properties of the &ldquo, NSS-Spanish version&rdquo, and validates a short-form version. A cross-sectional design was carried out for this study. A reliability analysis and a confirmatory factor analysis and an exploratory factor analysis were undertaken. Items were systematically identified for reduction using statistical and theoretical analysis. Correlation testing and criterion validity confirmed scale equivalence. A total of 2195 Registered Nurses and 1914 Licensed Practical Nurses were enrolled. The original 34-item scale obtained a good internal consistency but an unsatisfactory confirmatory and exploratory factor analysis. The short-form Nursing Stress Scale (11-items) obtained a good internal consistency for Registered Nurses (&alpha, = 0.83) and for Licensed Practical Nurses (&alpha, = 0.79). Both Nursing Stress Scales obtained a strong correlation for Registered Nurses (rho = 0.904) and for Licensed Practical Nurses (rho = 0.888). The 11-item version of the Nursing Stress Scale is a valid and reliable scale to assess stress perception among Registered Nurses and Licensed Practical Nurses. Its short-form nature improves the psychometric properties and the feasibility of the tool.

Published
2020

40. Hospital-Wide SARS-CoV-2 seroprevalence in health care workers in a Spanish teaching hospital

Author

Mª Isabel Galán, María Velasco, Mª Luisa Casas, Mª José Goyanes, Gil Rodríguez-Caravaca, Juan E. Losa-García, Carmen Noguera, Virgilio Castilla, Alejandro Algora Weber, Juan Carlos Alonso Punter, María Teresa Alonso Salazar, Gregorio Bonilla Zafra, M. Mercedes Bueno Campaña, Camilo Carrión Pulido, Ana Isabel Díaz Cuasante, Aurora Fabero Jiménez, Rosa María Fariña García, María Isabel González Anglada, Carlos Guijarro Herraiz, M. Mercedes Izquierdo Patron, Susana Lorenzo Martínez, Margarita Mosquera González, Montserrat Pérez Encinas, Elia Pérez Fernández, Francisco José Pérez Vega, and Maria Esther Renilla Sánchez

Subjects
0301 basic medicine, Microbiology (medical), Adult, Male, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Health Personnel, education, 030106 microbiology, Logistic regression, Asymptomatic, Infección nosocomial, Teaching hospital, 03 medical and health sciences, 0302 clinical medicine, Cross infection, Seroepidemiologic Studies, Internal medicine, Health care, Seroprevalencia, medicine, Seroprevalence, Humans, 030212 general & internal medicine, Hospitals, Teaching, business.industry, Transmission (medicine), SARS-CoV-2, COVID-19, Cross-Sectional Studies, Immunoglobulin G, Trabajador sanitario, RNA, Viral, Original Article, Female, medicine.symptom, business
Abstract

Introduction Hospital-wide SARS-CoV-2 seroprevalence is rarely explored and can identify areas of unexpected risk. We determined the seroprevalence against SARS-CoV-2 in all health care workers (HCW) at a hospital. Methods Cross-sectional study (14-27/04/2020). We determined SARS-CoV-2 IgG by ELISA in all HCW including external workers of a teaching hospital in Madrid. They were classified by professional category, working area, and risk for SARS-CoV-2 exposure. Results Among 2919 HCW, 2590 (88,7%) were evaluated. The mean age was 43.8 years (SD 11.1), and 73.9% were females. Globally, 818 (31.6%) workers were IgG positive with no differences for age, sex or previous diseases. Of these, 48.5% did not report previous symptoms. Seropositivity was more frequent in high- (33.1%) and medium- (33.8%) than in low-risk areas (25.8%, p = 0.007), but not for hospitalization areas attending COVID-19 and non-COVID-19 patients (35.5 vs 38.3% p > 0.05). HWC with a previous SARS-CoV2 PCR-positive test were IgG seropositive in 90.8%. By multivariate logistic regression analysis seropositivity was significantly associated with being physicians (OR 2.37, CI95% 1.61–3.49), nurses (OR 1.67, CI95% 1.14–2.46), nurse assistants (OR 1.84, CI95% 1.24–2.73), HCW working at COVID-19 hospitalization areas (OR 1.71, CI95% 1.22–2.40), non-COVID-19 hospitalization areas (OR 1.88, CI95% 1.30–2.73), and at the Emergency Room (OR 1.51, CI95% 1.01–2.27). Conclusions Seroprevalence uncovered a high rate of infection previously unnoticed among HCW. Patients not suspected of having COVID-19 as well as asymptomatic HCW may be a relevant source for nosocomial SARS-CoV-2 transmission.

Published
2020

41. Managing work flow in high enrolling trials: The development and implementation of a sampling strategy in the PREPARE trial

Author

David Pogorzelski, Uyen Nguyen, Paula McKay, Lehana Thabane, Megan Camara, Lolita Ramsey, Rachel Seymour, J. Brett Goodman, Sheketha McGee, Joanne Fraifogl, Andrea Hudgins, Stephanie L. Tanner, Mohit Bhandari, Gerard P. Slobogean, Sheila Sprague, Jeffrey Wells, Jean-Claude D'Alleyrand, Anthony D. Harris, Daniel C. Mullins, Amber Wood, Gregory J. Della Rocca, Joan Hebden, Kyle J. Jeray, Lucas Marchand, Lyndsay M. O'Hara, Robert Zura, Michael J. Gardner, Jenna Blasman, Jonah Davies, Stephen Liang, Monica Taljaard, P.J. Devereaux, Gordon H. Guyatt, Diane Heels-Ansdell, Debra Marvel, Jana Palmer, Jeff Friedrich, Nathan N. O'Hara, Ms. Frances Grissom, I. Leah Gitajn, Saam Morshed, Robert V. O'Toole, Bradley A. Petrisor, Franca Mossuto, Manjari G. Joshi, Justin Fowler, Jessica Rivera, Max Talbot, Shannon Dodds, Alisha Garibaldi, Silvia Li, Alejandra Rojas, Taryn Scott, Gina Del Fabbro, Olivia Paige Szasz, Andrea Howe, Joshua Rudnicki, Haley Demyanovich, Kelly Little, C. Daniel Mullins, Michelle Medeiros, Eric Kettering, Diamond Hale, Andrew Eglseder, Aaron Johnson, Christopher Langhammer, Christopher Lebrun, Theodore Manson, Jason Nascone, Ebrahim Paryavi, Raymond Pensy, Andrew Pollak, Marcus Sciadini, Yasmin Degani, Haley K. Demyanovich, Katherine Joseph, Brad A. Petrisor, Herman Johal, Bill Ristevski, Dale Williams, Matthew Denkers, Krishan Rajaratnam, Jamal Al-Asiri, Jordan Leonard, Francesc A. Marcano-Fernández, Jodi Gallant, Federico Persico, Marko Gjorgjievski, Annie George, Roman M. Natoli, Greg E. Gaski, Todd O. McKinley, Walter W. Virkus, Anthony T. Sorkin, Jan P. Szatkowski, Joseph R. Baele, Brian H. Mullis, Lauren C. Hill, Patrick Osborn, Sarah Pierrie, Eric Martinez, Joseph Kimmel, John D. Adams, Michael L. Beckish, Christopher C. Bray, Timothy R. Brown, Andrew W. Cross, Timothy Dew, Gregory K. Faucher, Richard W. Gurich, David E. Lazarus, S. John Millon, M. Jason Palmer, Scott E. Porter, Thomas M. Schaller, Michael S. Sridhar, John L. Sanders, L. Edwin Rudisill, Michael J. Garitty, Andrew S. Poole, Michael L. Sims, Clark M. Walker, Robert M. Carlisle, Erin Adams Hofer, Brandon S. Huggins, Michael D. Hunter, William A. Marshall, Shea Bielby Ray, Cory D. Smith, Kyle M. Altman, Julia C. Bedard, Markus F. Loeffler, Erin R. Pichiotino, Austin A. Cole, Ethan J. Maltz, Wesley Parker, T. Bennett Ramsey, Alex Burnikel, Michael Colello, Russell Stewart, Jeremy Wise, M. Christian Moody, Rebecca G. Snider, Christine E. Townsend, Kayla H. Pham, Abigail Martin, Emily Robertson, Theodore Miclau, Utku Kandemir, Meir Marmor, Amir Matityahu, R. Trigg McClellan, Eric Meinberg, David Shearer, Paul Toogood, Anthony Ding, Erin Donohue, Tigist Belaye, Eleni Berhaneselase, Alexandra Paul, Kartik Garg, Joshua L. Gary, Stephen J. Warner, John W. Munz, Andrew M. Choo, Timothy S. Achor, Milton L. 'Chip' Routt, Mayank Rao, Guillermo Pechero, Adam Miller, Jennifer E. Hagen, Matthew Patrick, Richard Vlasak, Thomas Krupko, Kalia Sadasivan, Chris Koenig, Daniel Bailey, Daniel Wentworth, Chi Van, Justin Schwartz, Niloofar Dehghan, Clifford B. Jones, J Tracy Watson, Michael McKee, Ammar Karim, Michael Talerico, Debra L. Sietsema, Alyse Williams, Tayler Dykes, William T. Obremskey, Amir Alex Jahangir, Manish Sethi, Robert Boyce, Daniel J. Stinner, Phillip Mitchell, Karen Trochez, Andres Rodriguez, Vamshi Gajari, Elsa Rodriguez, Charles Pritchett, Christina Boulton, Jason Lowe, Jason Wild, John T. Ruth, Michel Taylor, Andrea Seach, Sabina Saeed, Hunter Culbert, Alejandro Cruz, Thomas Knapp, Colin Hurkett, Maya Lowney, Michael Prayson, Indresh Venkatarayappa, Brandon Horne, Jennifer Jerele, Linda Clark, Francesc Marcano-Fernández, Montsant Jornet-Gibert, Laia Martínez-Carreres, David Martí-Garín, Jorge Serrano-Sanz, Joel Sánchez-Fernández, Matsuyama Sanz-Molero, Alejandro Carballo, Xavier Pelfort, Francesc Acerboni-Flores, Anna Alavedra-Massana, Neus Anglada-Torres, Alexandre Berenguer, Jaume Cámara-Cabrera, Ariadna Caparros-García, Ferran Fillat-Gomà, Ruben Fuentes-López, Ramona Garcia-Rodriguez, Nuria Gimeno-Calavia, Guillem Graells-Alonso, Marta Martínez-Álvarez, Patricia Martínez-Grau, Raúl Pellejero-García, Ona Ràfols-Perramon, Juan Manuel Peñalver, Mònica Salomó Domènech, Albert Soler-Cano, Aldo Velasco-Barrera, Christian Yela-Verdú, Mercedes Bueno-Ruiz, Estrella Sánchez-Palomino, Ernesto Guerra, Yaiza García, Nicholas M. Romeo, Heather A. Vallier, Mary A. Breslin, Eleanor S. Wilson, Leanne K. Wadenpfuhl, Paul G. Halliday, Darius G. Viskontas, Kelly L. Apostle, Dory S. Boyer, Farhad O. Moola, Bertrand H. Perey, Trevor B. Stone, H. Michael Lemke, Mauri Zomar, Ella Spicer, Chen 'Brenda' Fan, Kyrsten Payne, Kevin Phelps, Michael Bosse, Madhav Karunakar, Laurence Kempton, Stephen Sims, Joseph Hsu, Christine Churchill, Claire Bartel, Robert Miles Mayberry, Maggie Brownrigg, Cara Girardi, Ada Mayfield, Robert A. Hymes, Cary C. Schwartzbach, Jeff E. Schulman, A. Stephen Malekzadeh, Michael A. Holzman, James S. Ahn, Farhanaz Panjshiri, Sharmistha Das, Antoinisha D. English, Sharon M. Haaser, Jaslynn A.N. Cuff, Holly Pilson, Eben A. Carroll, Jason J. Halvorson, Sharon Babcock, Martha B. Holden, Debra Bullard, Wendy Williams, Thomas F. Higgins, Justin M. Haller, David L. Rothberg, Ashley Neese, Mark Russell, Marcus Coe, Kevin Dwyer, Devin S. Mullin, Clifford A. Reilly, Peter DePalo, Amy E. Hall, Marilyn Heng, Mitchel B. Harris, R. Malcolm Smith, David W. Lhowe, John G. Esposito, Mira Bansal, Patrick F. Bergin, George V. Russell, Matthew L. Graves, John Morellato, Heather K. Champion, Leslie N. Johnson, Sheketha L. McGee, Eldrin L. Bhanat, Samir Mehta, Derek Donegan, Jaimo Ahn, Annamarie Horan, Mary Dooley, Ashley Kuczinski, Ashley Iwu, David Potter, Robert VanDemark, Branden Pfaff, Troy Hollinsworth, Michael J. Weaver, Arvind G. von Keudell, Michael F. McTague, Elizabeth M. Allen, Todd Jaeblon, Robert Beer, Mark J. Gage, Rachel M. Reilly, and Cindy Sparrow

Subjects
Pragmatic, medicine.medical_specialty, Comparative effectiveness research, Pharmacy, Sampling framework, Cluster crossover, Sampling strategy, Article, Odds, 03 medical and health sciences, 0302 clinical medicine, Health care, medicine, 030212 general & internal medicine, Sampling, Pharmacology, lcsh:R5-920, Descriptive statistics, business.industry, Sampling (statistics), General Medicine, Test (assessment), Work flow, Family medicine, business, lcsh:Medicine (General), 030217 neurology & neurosurgery
Abstract

Author(s): Pogorzelski, David; Nguyen, Uyen; McKay, Paula; Thabane, Lehana; Camara, Megan; Ramsey, Lolita; Seymour, Rachel; Goodman, J Brett; McGee, Sheketha; Fraifogl, Joanne; Hudgins, Andrea; Tanner, Stephanie L; Bhandari, Mohit; Slobogean, Gerard P; Sprague, Sheila; PREP-IT Investigators Executive Committee:; Steering Committee; Adjudication Committee; Data and Safety Monitoring Committee; Research Methodology Core; Patient Centred Outcomes Core; Orthopaedic Surgery Core; Operating Room Core; Infectious Disease Core; Military Core; McMaster University Methods Center; University of Maryland School of Medicine Administrative Center; University of Maryland School of Pharmacy, The PATIENTS Program; PREP-IT Clinical Sites: Lead Clinical Site (Aqueous-PREP and PREPARE); Aqueous-PREP and PREPARE; Aqueous-PREP; PREPARE; PREP-IT Investigators Executive Committee | Abstract: IntroductionPragmatic trials in comparative effectiveness research assess the effects of different treatment, therapeutic, or healthcare options in clinical practice. They are characterized by broad eligibility criteria and large sample sizes, which can lead to an unmanageable number of participants, increasing the risk of bias and affecting the integrity of the trial. We describe the development of a sampling strategy tool and its use in the PREPARE trial to circumvent the challenge of unmanageable work flow.MethodsGiven the broad eligibility criteria and high fracture volume at participating clinical sites in the PREPARE trial, a pragmatic sampling strategy was needed. Using data from PREPARE, descriptive statistics were used to describe the use of the sampling strategy across clinical sites. A Chi-square test was performed to explore whether use of the sampling strategy was associated with a reduction in the number of missed eligible patients.Results7 of 20 clinical sites (35%) elected to adopt a sampling strategy. There were 1539 patients excluded due to the use of the sampling strategy, which represents 30% of all excluded patients and 20% of all patients screened for participation. Use of the sampling strategy was associated with lower odds of missed eligible patients (297/4545 (6.5%) versus 341/3200 (10.7%) p l 0.001).ConclusionsImplementing a sampling strategy in the PREPARE trial has helped to limit the number of missed eligible patients. This sampling strategy represents a simple, easy to use tool for managing work flow at clinical sites and maintaining the integrity of a large trial.

Published
2020

43. Evaluation of the impact of the Spanish Consensus Document on the approach to osteoarticular infections in Spain through the Paediatrics Osteoarticular Infections Network (RIOPED)

Author

Núñez Cuadros, Esmeralda, primary, Calvo, Cristina, additional, Saavedra-Lozano, Jesús, additional, Rueda, Rosa Alcobendas, additional, Garulo, Daniel Clemente, additional, Santaeufemia, F. José Sanz, additional, Campos, Leticia Martínez, additional, García, Alfredo Tagarro, additional, Fontecha, César G., additional, Melendo-Pérez, Susana, additional, Lovillo, Marisol Camacho, additional, Neyra, Lola Falcón, additional, Cruz, M. José Lirola, additional, Gil, Elena Colino, additional, Carreño, Patricia Tejera, additional, Canals, Luis Mayol, additional, Zarketa, Daniel Domenech, additional, Campaña, M. Mercedes Bueno, additional, Méndez, Carlos Pérez, additional, Gordillo, Neus Rius, additional, Cardona, Verónica, additional, Colom, Jaime Carrasco, additional, Fernández, Antonio Conejo, additional, Ramírez, Marta García, additional, Delgado, Rafael Díez, additional, Ordónez, Carmen Vázquez, additional, Tejada, Enrique Otheo de, additional, Gianzo, José Couceiro, additional, Arranz, Leonor, additional, García-Pardos, Carmen, additional, Piñeiro-Pérez, Roi, additional, Mancheño, Beatriz Bravo, additional, López-Molina, Inmaculada, additional, Acevedo, Adriana Vidal, additional, Antón, María Penín, additional, Coll, M. Teresa, additional, Soler, Berta Pujol, additional, Pérez, Pilar Ranchal, additional, Morales, Sara Pons, additional, Sevilla, Belén, additional, Hernández, María Méndez, additional, García-Mazarío, M. Jesús, additional, Martín, César Gavilán, additional, Fernández-Cooke, Elisa, additional, Canet, Anna, additional, Jiménez, Marta Ruiz, additional, González, Marina, additional, Rodríguez, Lourdes García, additional, Moreno, Carmen, additional, Lizarbe, Miren Oscoz, additional, Martín-Pedraz, Laura, additional, Lillo, Miguel Lillo, additional, Cepillo, Antonio J., additional, Soler-Palacín, Pere, additional, Ramakers, Jan, additional, Gasaball, Olga Calavia, additional, Ramo, Rebeca Lahoz, additional, Barrero, Pedro Terol, additional, Vilchez, M. José Muñoz, additional, Pérez, Victoria Fumadó, additional, Camps, Silvia Urraca, additional, Rodríguez, Elena Urbaneja, additional, Ortega, M. José Cilleruelo, additional, López, Agustín López, additional, Solas, Valentín Pineda, additional, Pedrab, Carla Monterde, additional, Molina, Rosa Roldán, additional, Masegosa-Casanova, Sandra, additional, Rodríguez, Paula Alcañiz, additional, Ruíz, Ana Menasalvas, additional, Arístegui-Fernández, Javier, additional, Garrote, Elisa, additional, Martinón-Torres, Federico, additional, Rivero-Calle, Irene, additional, Ramos, José Tomás, additional, Ramos, Marta Illán, additional, Montero, Beatriz Jiménez, additional, Pinedo, Begoña Losada, additional, Ibáñez, Borja Guarch, additional, Serrano, Marcelina Algar, additional, García, M. Dolores, additional, Pereira, Elena, additional, Rodríguez-Blanco, Silvia, additional, Fontán, Manuel Muñiz, additional, Reyes, Sagrario Bustabab, additional, Claros, Antonio Medina, additional, Oñós, Isabel Vives, additional, Perelló, M. Concepción Mir, additional, Barreiro, Natalia Cerdeira, additional, Barnés, María Ríos, additional, Patudo, Isabel Vara, additional, Martínez-Regueira, Soledad, additional, Domenech, Raquel Marín, additional, Vílchez, Juan Salvador, additional, Moreno, Jesús de la Cruz, additional, Laleona, Carmelo Guerrero, additional, Alonso, Matilde Bustillo, additional, Meléndez, Leticia Merino, additional, and Martín, Azucena García, additional

Published
2020
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44. Evaluación del impacto del Documento de Consenso español sobre el abordaje de las infecciones osteoarticulares en nuestro medio a través de la Red de Infecciones Osteoarticulares Pediátricas (RIOPed)

Author

Núñez Cuadros, Esmeralda, primary, Calvo Rey, Cristina, additional, Saavedra-Lozano, Jesús, additional, Rueda, Rosa Alcobendas, additional, Garulo, Daniel Clemente, additional, Santaeufemia, F. José Sanz, additional, Campos, Leticia Martínez, additional, García, Alfredo Tagarro, additional, Fontecha, César G., additional, Melendo-Pérez, Susana, additional, Lovillo, Marisol Camacho, additional, Neyra, Lola Falcón, additional, Cruz, M. José Lirola, additional, Gil, Elena Colino, additional, Carreño, Patricia Tejera, additional, Canals, Luis Mayol, additional, Zarketa, Daniel Domenech, additional, Campaña, M. Mercedes Bueno, additional, Méndez, Carlos Pérez, additional, Gordillo, Neus Rius, additional, Cardona, Verónica, additional, Colom, Jaime Carrasco, additional, Fernández, Antonio Conejo, additional, Ramírez, Marta García, additional, Delgado, Rafael Díez, additional, Ordónez, Carmen Vázquez, additional, Tejada, Enrique Otheo de, additional, Gianzo, José Couceiro, additional, Arranz, Leonor, additional, García-Pardos, Carmen, additional, Piñeiro-Pérez, Roi, additional, Mancheño, Beatriz Bravo, additional, López-Molina, Inmaculada, additional, Acevedo, Adriana Vidal, additional, Antón, María Penín, additional, Coll, M. Teresa, additional, Soler, Berta Pujol, additional, Pérez, Pilar Ranchal, additional, Morales, Sara Pons, additional, Sevilla, Belén, additional, Hernández, María Méndez, additional, García-Mazarío, M. Jesús, additional, Martín, César Gavilán, additional, Fernández-Cooke, Elisa, additional, Canet, Anna, additional, Jiménez, Marta Ruiz, additional, González, Marina, additional, Rodríguez, Lourdes García, additional, Moreno, Carmen, additional, Lizarbe, Miren Oscoz, additional, Martín-Pedraz, Laura, additional, Lillo, Miguel Lillo, additional, Cepillo, Antonio J., additional, Soler-Palacín, Pere, additional, Ramakers, Jan, additional, Gasaball, Olga Calavia, additional, Ramo, Rebeca Lahoz, additional, Barrero, Pedro Terol, additional, Vilchez, M. José Muñoz, additional, Pérez, Victoria Fumadó, additional, Camps, Silvia Urraca, additional, Rodríguez, Elena Urbaneja, additional, Ortega, M. José Cilleruelo, additional, López, Agustín López, additional, Solas, Valentín Pineda, additional, Pedrab, Carla Monterde, additional, Molina, Rosa Roldán, additional, Masegosa-Casanova, Sandra, additional, Rodríguez, Paula Alcañiz, additional, Ruíz, Ana Menasalvas, additional, Arístegui-Fernández, Javier, additional, Garrote, Elisa, additional, Martinón-Torres, Federico, additional, Rivero-Calle, Irene, additional, Ramos, José Tomás, additional, Ramos, Marta Illán, additional, Montero, Beatriz Jiménez, additional, Pinedo, Begoña Losada, additional, Ibáñez, Borja Guarch, additional, Serrano, Marcelina Algar, additional, García, M. Dolores, additional, Pereira, Elena, additional, Rodríguez-Blanco, Silvia, additional, Fontán, Manuel Muñiz, additional, Reyes, Sagrario Bustabab, additional, Claros, Antonio Medina, additional, Oñós, Isabel Vives, additional, Perelló, M. Concepción Mir, additional, Barreiro, Natalia Cerdeira, additional, Barnés, María Ríos, additional, Patudo, Isabel Vara, additional, Martínez-Regueira, Soledad, additional, Domenech, Raquel Marín, additional, Vílchez, Juan Salvador, additional, Moreno, Jesús de la Cruz, additional, Laleona, Carmelo Guerrero, additional, Alonso, Matilde Bustillo, additional, Meléndez, Leticia Merino, additional, and Martín, Azucena García, additional

Published
2020
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45. Epidemiological and clinical features of Kawasaki disease in Spain over 5 years and risk factors for aneurysm development. (2011-2016): KAWA-RACE study group

Author

Fernandez-Cooke, Elisa, Barrios Tascon, Ana, Sanchez-Manubens, Judith, Anton, Jordi, Grasa Lozano, Carlos Daniel, Aracil Santos, Javier, Villalobos Pinto, Enrique, Clemente Garulo, Daniel, Mercader Rodriguez, Beatriz, Bustillo Alonso, Matilde, Nunez Cuadros, Esmeralda, Navarro Gomez, Maria Luisa, Dominguez-Rodriguez, Sara, Calvo, Cristina, Moreno Perez, David, Martin Cantero, Maria, Carazo Gallego, Begona, Martinez Campos, Leticia Isabel, Sanchez Garcia, Fernando, Camacho Lovillo, Marisol, Marques, Renata, Neth, Olaf, Fernandez Silveira, Laura, Sanchez Forte, Miguel, Ortega Montes, Angeles, Bravo Mancheno, Beatriz, Camacho, Margarita, Medina Claros, Antonio F., Salido, Carlos, Chulian Cruz, Rafael, Torres Rico, Maria, Tejero Hernandez, Ma Angeles, Gomez Guzman, Elena, Arroyo Marin, Ma Jose, Rumbao Aguirre, Jose, Lirola Cruz, Ma Jose, Maya Carrasco, Kety, Rodriguez Gonzalez, Moises, Blanca Jover, Enrique, Ruiz Lopez, Aida, Uberos Fernandez, Jose, Ibanez Alcalde, Maria Mercedes, Collado, Pilar, Guerrero Laleona, Carmelo, Jimenez Montanes, Lorenzo, Ayerza Casas, Ariadna, Montes Zapico, Barbara, Perez Mendez, Carlos, Fernandez Aracama, Javier, Rodriguez, Lucia, Ibanez Fernandez, Maria Aleida, Navarro Campo, Sandra, Escriba Bori, Silvia, Mir Perello, Maria Concepcion, de la Fuente Sanchez, Ma Angeles, Aparicio Garcia, Patricia, Briales, Carlos, Castilla Crespi, Joaquin, Colino Gil, Maria Elena, Delgado Cabrera, Nerea, Bello Naranjo, Ana, Poch Paez, Jesus, Garcia Yanez, Moneyba, Gonzalez Garcia, Montse, Pereira Bezanilla, Elena, Jimenez Montero, Beatriz, Dominguez Garcia, Olga, Losada Pinedo, Begona, Inigo Martin, Gema, Escribano Gomez, Lucia Maria, Cepillo, Antonio, Lillo Lillo, Miguel, Isabel Buedo, Maria, del Rey, Laura, Urbaneja Rodriguez, Elena, Rellan Rodriguez, Sara, Cantero, Teresa, Plata Izquierdo, Beatriz, Garcia-Cuenllas Alvarez, Luisa, Oulego Erroz, Ignacio, Perez Santaolalla, Elena, Alcalde Martin, Carlos, Centeno Malfaz, Fernando, Perez Gutierrez, Elena, Jimenez Casso, Marisol, Prada, Fredy, Bou, Rosa, Iglesias, Estibaliz, Calzada, Joan, Calavia Garsaball, Olga, Tobena Rue, Marc, Giralt Garcia, Gemma, Yevenes Ruiz, Silvia, Lobato, Zulema, Rius Gordillo, Neus, Pascual Torres, Montserrat, Mendez Hernandez, Maria, Garcia, Lourdes, Flores Villar, Sergio, Minguell Domingo, Laura, Ballester, Anna, Miralles, Ana, Pujol Soler, Berta, Foguet Vidal, Anton, Sala Castellvi, Pere, Serrano Aguiar, Angelita, Siurana Rodriguez, Jose Manuel, Sangorrin Iranzo, Anna, Alvarez Perez, Roser, Ribes Cajas, Paula, Genaro i Jornet, Pere, Grande Tejada, Ana, Zarallo, Cristina, Martinon-Torres, Federico, Rivero Calle, Irene, Justicia Grande, Antonio, Ruiz Saez, Beatriz, Lopez Sousa, Maria, Souto Vilas, Alejandro, Lopez Abe, Bernardo, de Miguel Esteban, Elisa, Riano Mendez, Bibiana, Blazquez, Daniel, Rojo Conejo, Pablo, Gonzalez Tome, Maribel, Grasa Lozano, Carlos, Toral, Belen, Albert De la Torre, Leticia, de Inocencio, Jaime, Santos, Mar, Diaz-Delgado de la Pena, Rafael, Collado Ramos, Paz, Tagarro, Alfredo, Raga, Teresa, Latorre, Libertad, Guillen, Sara, Callejas Caballero, Ignacio, Prieto Tato, Luis Manuel, Guzman Monagas, Maria Fernanda, Jimenez Lopez, Isabel, Villagra, Sandra, Arreo, Viviana, Pineiro Perez, Roi, de la Parte, Maria, Tamariz-Martes, Amalia, Llorente Romano, Marta, Hernandez Ruperez, Belen, Rodriguez Martin, Sonia, Rojo Sombrero, Henar, Garcia Cerro, Estefania, Mate Cano, Irene, Villares Alonso, Marta, Osuna Marco, Marta Pilar, Jensen Veron, Julia, Rodriguez Mesa, Maria Dolores, Rueda Esteban, Santiago, Ramos Amador, Jose Tomas, Gonzalez Menchen, Cristina, Jimenez Jimenez, Ana Belen, Galan, Pilar, Perez Campos, Dolores, Mercedes Bueno, Ma, Crespo Marcos, David, de Tejada Barasoain, Enrique Otheo, Sifuentes Giraldo, Walter Alberto, Gamir Gamir, Maria Luz, Cilleruelo Ortega, Maria Jose, Lopez Lopez, Agustin, Sanchez Vaquerizo, Cristina, Usano Carrasco, Ana Isabel, Moreno Gomez, Ester, Carrasco Colom, Jaime, Carvajal del Castillo, Olga, Del Pozo Menendez, Beatriz, Badillo Navarro, Katie, Baquero, Fernando, Deiros Bronte, Lucia, Fernandez Fraga, Pablo, Dominguez, Nieves, Castro Garcia, Francisco, Vera Romero, Elena, Herrera Chamorro, Agueda, Alcaniz Rodriguez, Paula, Sorli Garcia, Moises, Rex Nicolas, Maria Concepcion, Lorente Nicolas, Ana, Martinez Oloron, Patricia, Rocandio Cilveti, Beatriz, Berridi, Amaia, Santos-Diez Vazquez, Laura, Fernandez, Olaia, Perez Tamarit, Amparo, Calvo, Inmaculada, Lopez, Berta, Gonzalez Fernandez, Ma Isabel, Carmen Otero, Ma, Oltra, Manuel, Dapena Archiles, Marta, Sanchez, Paco, Gavilan, Cesar, Izquierdo Fos, Ignacio, Serrano Robles, Maria Isabel, Herranz Sanchez, Yolanda, KAWA-RACE Study Grp, and Sociedad Española de Reumatología Pediátrica

Subjects
Male, Pediatrics, Epidemiology, Physiology, humanos, Fevers, adolescente, Pathology and Laboratory Medicine, Vascular Medicine, Biochemistry, 0302 clinical medicine, Animal Cells, Risk Factors, Medicine and Health Sciences, 030212 general & internal medicine, Kawasaki Disease, Child, síndrome mucocutáneo linfonodular, education.field_of_study, Multidisciplinary, Organic Compounds, resultado del tratamiento, Coronary Aneurysm, Anemia, Hematology, Prognosis, Body Fluids, Chemistry, pronóstico, Blood, Treatment Outcome, Echocardiography, Child, Preschool, Physical Sciences, Medicine, Steroids, Female, Anatomy, Cellular Types, Aneurysms, Research Article, Ecocardiografia, Systemic vasculitis, Platelets, Vasculitis, medicine.medical_specialty, Adolescent, Science, Immunology, Population, Mucocutaneous Lymph Node Syndrome, Autoimmune Diseases, 03 medical and health sciences, Signs and Symptoms, Aneurysm, Diagnostic Medicine, 030225 pediatrics, medicine, Humans, factores de riesgo, Vascular Diseases, Hemoglobin, Aneurismes, education, lactante, Blood Cells, business.industry, Organic Chemistry, Chemical Compounds, Biology and Life Sciences, Proteins, Infant, Retrospective cohort study, Cell Biology, medicine.disease, aneurisma coronario, Spain, Medical Risk Factors, Etiology, Clinical Immunology, Kawasaki disease, Clinical Medicine, business
Abstract

KAWA-RACE study group., [Background] Kawasaki disease (KD) is an acute self-limited systemic vasculitis of unknown etiology affecting mainly children less than 5 years of age. Risk factors for cardiac involvement and resistance to treatment are insufficiently studied in non-Japanese children., [Objective] This study aimed to investigate the epidemiology, clinical features and risk factors for resistance to treatment and coronary artery lesions (CAL) in KD in Spain., [Methods] Retrospective study (May 2011-June 2016) of all patients less than 16 years of age diagnosed with KD included in KAWA-RACE network (84 Spanish hospitals)., [Results] A total of 625 cases were analyzed, 63% were males, 79% under 5 year-olds and 16.8% younger than 12 months. On echocardiographic examination CAL were the most frequent findings (23%) being ectasia the most common (12%). Coronary aneurysms were diagnosed in 9.6%, reaching 20% in infants under 12 months (p 900,000 cells/mm3, maximum temperature < 39.5°C, total duration of fever > 10 days and fever before treatment ≥ 8 days as independent risk factors for developing coronary aneurysms., [Conclusions] In our population, children under 12 months develop coronary aneurysms more frequently and children with KD with anemia and leukocytosis have high risk of cardiac involvement. Adding steroids early should be considered in those patients, especially if the treatment is not started before 8 days of fever. A score applicable to non-Japanese children able to predict the risk of aneurysm development and IVIG resistance is necessary., CC received a grant from Spanish Society of Paediatric Rheumatology (SERPE), 2015.

Published
2019
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46. The impact of false warnings on partial and full lane departure warnings effectiveness and acceptance in car driving

Author

Alexandra Fort, Jordan Navarro, Jonathan Deniel, Mercedes Bueno, Christophe Jallais, Elsa Yousfi, Laboratoire d'Etude des Mécanismes Cognitifs (EMC), Université Lumière - Lyon 2 (UL2), Laboratoire Ergonomie et Sciences Cognitives pour les Transports (IFSTTAR/TS2/LESCOT), and Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Université de Lyon

Subjects
Adult, Male, Automobile Driving, Engineering, Lane departure warning system, ALERTE, Applied psychology, VOIE DE CIRCULATION, ALERT MISS, ComputerApplications_COMPUTERSINOTHERSYSTEMS, Physical Therapy, Sports Therapy and Rehabilitation, Human Factors and Ergonomics, Car driving, Computer security, computer.software_genre, User-Computer Interface, Young Adult, 0502 economics and business, Humans, Attention, 0501 psychology and cognitive sciences, CONDUITE, WARNING SYSTEM, AVERTISSEMENT, 050107 human factors, LANE DEPARTURE, FALSE ALERT, 050210 logistics & transportation, [SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior, STERRING BEHAVIOUR, business.industry, 05 social sciences, Equipment Design, Middle Aged, ACCEPTABILITE, 13. Climate action, SUIVI DE VOIE, Female, Safety, business, Automobiles, computer
Abstract

In the past, lane departure warnings (LDWs) were demonstrated to improve driving behaviours during lane departures but little is known about the effects of unreliable warnings. This experiment focused on the influence of false warnings alone or in combination with missed warnings and warning onset on assistance effectiveness and acceptance. Two assistance unreliability levels (33 and 17%) and two warning onsets (partial and full lane departure) were manipulated in order to investigate interaction. Results showed that assistance, regardless unreliability levels and warning onsets, improved driving behaviours during lane departure episodes and outside of these episodes by favouring better lane-keeping performances. Full lane departure and highly unreliable warnings, however, reduced assistance efficiency. Drivers' assistance acceptance was better for the most reliable warnings and for the subsequent warnings. The data indicate that imperfect LDWs (false warnings or false and missed warnings) further improve driving behaviours compared to no assistance. Practitioner Summary: This study revealed that imperfect lane departure warnings are able to significantly improve driving performances and that warning onset is a key element for assistance effectiveness and acceptance. The conclusion may be of particular interest for lane departure warning designers.

Published
2016
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47. Efficacité des alertes signalant un risque de collision par l’arrière chez le conducteur distrait

Author

Daniel Ndiaye, Mercedes Bueno, Christophe Jallais, Colette Fabrigoule, Jordan Navarro, Alexandra Fort, Laboratoire Ergonomie et Sciences Cognitives pour les Transports (IFSTTAR/TS2/LESCOT), Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Université de Lyon, Sommeil, Attention et Neuropsychiatrie [Bordeaux] (SANPSY), Université de Bordeaux (UB)-CHU de Bordeaux Pellegrin [Bordeaux]-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Etude des Mécanismes Cognitifs (EMC), Université Lumière - Lyon 2 (UL2), Laboratoire Exploitation, Perception, Simulateurs et Simulations (IFSTTAR/COSYS/LEPSIS), and Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR)-Communauté Université Paris-Est

Subjects
[SPI.OTHER]Engineering Sciences [physics]/Other, 050210 logistics & transportation, reliability, auditory warning, ALERTE, Computer science, driving assistance, 05 social sciences, Transportation, AIDE ELECTRONIQUE A LA CONDUITE, attention, SIGNAL SONORE, FIABILITE, 0502 economics and business, Automotive Engineering, ACOUSTIQUE, 0501 psychology and cognitive sciences, AIDE A LA CONDUITE, Humanities, distraction, 050107 human factors
Abstract

This paper presents a review of the literature to shed light on the impact of distractions on the effectiveness of warning indicating a risk of collision. The rear-end collisions account for a significant share of injury accidents. One of the major contributing factors to these collisions is drivers’ inattention. To reduce the impact of this kind of collisions, driving assistance consisting in alerts have emerged. The effectiveness of these alerts has been evaluated in different situations (simulation, simulator and on road) in non-distracted and distracted drivers. In the latter case, the majority of distraction tasks used involves a diversion of eyes off the road to a device inside the vehicle, coupled or not with manual handling. However, few studies have also examined the impact of distractive tasks having only a cognitive component. The data show that the efficiency of an alert may depend on the interaction between its sensory modality and that of the distractive task. Finally, the effectiveness of these systems can also be affected by the interaction between its reliability and being or not distracted. This review raises research questions that should be further developed to ensure the safety of a larger number of users.; Ce papier présente une revue de la littérature visant à apporter un éclairage sur l'impact des distractions sur l'efficacité d'alerte signalant un risque de collision. Les collisions par l'arrière représentent une part non négligeable des accidents corporels. Un des facteurs contributifs majeurs à ces collisions est l'inattention des conducteurs. Afin de diminuer l'impact de ces collisions, des assistances à la conduite de type alerte ont vu le jour. L'efficacité de ces alertes a été évaluée dans différentes situations (par simulation, sur simulateur et sur route) chez des conducteurs non distraits et distraits. Dans le derniers cas, la majorité des tâches distractives employées impliquent un détournement du regard de la route vers un dispositif à l'intérieur du véhicule couplé ou non avec une manipulation manuelle. Toutefois, quelques études se sont également intéressées à l'impact de tâches distractives ayant seulement une composante cognitive. Les données montrent que l'efficacité d'une alerte peut dépendre de l'interaction entre sa modalité sensorielle et celle de la tâche distractive. Enfin, l'efficacité de ces systèmes peut également être impactée par l'interaction entre sa fiabilité et le fait d'être ou non distrait. Cette revue soulève des questions de recherche qui devraient encore être approfondies en vue de garantir la sécurité du plus grand nombre d'usagers.

Published
2016
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48. Lung ultrasound for prediction of respiratory support in infants with acute bronchiolitis: A cohort study

Author

Regina Echevarria, Teresa Del Rosal, Talía Sainz, Ana Méndez-Echevarría, Cristina Calvo, Marta Ruperez‐Lucas, Alfredo Tagarro, Mercedes Bueno‐Campaña, Maria Alba, Libertad Latorre, and Maria L. Herrreros

Subjects
Pulmonary and Respiratory Medicine, Male, medicine.medical_specialty, Ultrasonografía, Patient Admission, Predictive Value of Tests, Internal medicine, medicine, Humans, Prospective Studies, Primera infancia, Lung, Respiratory Tract Infections, Ultrasonography, Noninvasive Ventilation, Respiratory tract infections, business.industry, Respiration, Infant, Bronquiolitis, Aparato respiratorio, medicine.disease, Prognosis, Respiratory support, Lung ultrasound, Multicenter study, Acute Bronchiolitis, Bronchiolitis, Pediatrics, Perinatology and Child Health, Acute Disease, Multivariate Analysis, Breathing, Female, business, Cohort study
Abstract

Objective: Respiratory tract infections are among the most common causes of morbidity and mortality worldwide. Acute bronchiolitis (AB) is the leading cause of hospital admission among infants. Clinical scores have proven to be inaccurate in predicting prognosis. Our aim was to build a score based on findings of lung ultrasound (LU) performed at admission, to stratify patients at risk of needing respiratory support (non-invasive and invasive ventilation). Study design: Prospective, multicenter study including infants 1 cm was the main factor associated to NIV (RR 4.4; [CI95%1.8-10.8]) The LU score built according to the findings on admission showed an AUC: 0.845(CI95%:0.78-0.91). A score ≥3.5 showed a sensitivity of 89.1% (CI95%:78.2-94.9%) and specificity of 56% (CI95%: 45.3-66.1%) CONCLUSIONS: Among infants below 6 months of age admitted with AB, point-of-care LU was a helpful tool to identify patients at risk of needing respiratory support. Sin financiación 2.534 JCR (2019) Q2, 33/128 Pediatrics 0.927 SJR (2019) Q1, 55/311 Pediatrics, Perinatology and Child Health No data IDR 2019 UEM

Published
2018

49. Mid-regional pro-adrenomedullin could be a biomarker of severity in bronchiolitis

Author

Cristina Calvo, Marta Rupérez Lucas, Mercedes Bueno Campaña, Rocío de la Morena Martinez, Lucia Moran Roldan, and Adelaida Fernández Rincon

Subjects
Male, Risk Assessment, Severity of Illness Index, Cohort Studies, 03 medical and health sciences, Adrenomedullin, 0302 clinical medicine, Hospitals, Urban, 030225 pediatrics, Severity of illness, Medicine, Humans, 030212 general & internal medicine, business.industry, Disease progression, Infant, Newborn, Infant, General Medicine, medicine.disease, Hospitals, Pediatric, Prognosis, Infant newborn, Multicenter study, Bronchiolitis, Spain, Pediatrics, Perinatology and Child Health, Immunology, Disease Progression, Biomarker (medicine), Mid regional pro adrenomedullin, Female, business, Biomarkers
Published
2018

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