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2. Vascular access for hemodialysis in Italy: What a national survey reveals

Author

Napoli, Marcello, primary, Guzzi, Francesco, additional, Morale, Walter, additional, Lomonte, Carlo, additional, Galli, Franco, additional, Lodi, Massimo, additional, Bonforte, Giuseppe, additional, Bonucchi, Decenzio, additional, Brunori, Giuliano, additional, Buzzi, Laura, additional, Forneris, Giacomo, additional, Gallieni, Maurizio, additional, Meola, Mario, additional, Pirozzi, Nicola, additional, Sessa, Concetto, additional, Spina, Monica, additional, and Tazza, Luigi, additional

Published
2024
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3. Contributors

Author

Albright, Robert C., primary, Amerling, Richard, additional, Angeli, Paolo, additional, Angelotti, Maria Lucia, additional, Antonelli, Massimo, additional, Antoniotti, Riccardo, additional, Arulkumaran, Nishkantha, additional, Asfar, Pierre, additional, Ash, Stephen R., additional, Aucella, Filippo, additional, Aucella, Francesco, additional, Ave, Samuele, additional, Bagshaw, Sean M., additional, Balaraman, Vasanthi, additional, Baldwin, Ian, additional, Bargman, Joanne M., additional, Barletta, Gina-Marie, additional, Barletta, Jeffrey F., additional, Barnela, Shriganesh R., additional, Bayır, Hülya, additional, Beaulieu, Monica, additional, Bellasi, Antonio, additional, Bellomo, Rinaldo, additional, Beloncle, François, additional, Bhansali, Arjun, additional, Bihorac, Azra, additional, Billings, Frederic T., additional, Birk, Horst-Walter, additional, Bonilla-Reséndiz, Luis Ignacio, additional, Bouchard, Josée, additional, Bourke, Edmund, additional, Braitberg, George, additional, Brendolan, Alessandra, additional, Brocca, Alessandra, additional, Brophy, Patrick D., additional, Bucala, Richard, additional, Bunchman, Timothy E., additional, Burdmann, Emmanuel A., additional, Busse, Laurence W., additional, Caires, Renato Antunes, additional, Caironi, Pietro, additional, Camilla, Roberta, additional, Campos, Israel, additional, Canaud, Bernard, additional, Cantaluppi, Vincenzo, additional, Martinez, Maria P., additional, Capasso, Giovambattista, additional, Carcillo, Joseph A., additional, Carlesso, Eleonora, additional, Casino, Francesco G., additional, Castellano, Giuseppe, additional, Catania, Matteo, additional, Cawcutt, Kelly A., additional, Cerda, Jorge, additional, Charen, Elliot, additional, Chawla, Lakhmir S., additional, Chiaramonte, Stefano, additional, Chua, Horng-Ruey, additional, Cianciaruso, Bruno, additional, Ciceri, Paola, additional, Cieslak, Jacek, additional, Clark, William R., additional, Claure-Del Granado, Rolando, additional, Clementi, Anna, additional, Co, Ivan N., additional, Coelho, Fernanda Oliveira, additional, Conte, Ferruccio, additional, Corey, Howard E., additional, Cosmai, Laura, additional, Costalonga, Elerson Carlos, additional, Costamagna, Andrea, additional, Costanzo, Maria Rosa, additional, Cozzolino, Mario, additional, Cramer, Carl H., additional, Cravedi, Paolo, additional, Crepaldi, Carlo, additional, Creteur, Jacques, additional, Crew, R. John, additional, da Costa e Silva, Verônica Torres, additional, Davenport, Andrew, additional, Davies, Andrew R., additional, D'Costa, Rohit, additional, Dean, Dawson F., additional, Debiais, Charlotte, additional, de Cal, Massimo, additional, Dedhia, Paras, additional, de Grooth, Harm-Jan, additional, Dell'Aquila, Roberto, additional, Dellepiane, Sergio, additional, Dellinger, Richard Phillip, additional, Del Vecchio, Lucia, additional, Depner, Thomas A., additional, De Rosa, Silvia, additional, Deutschman, Clifford S., additional, Devarajan, Prasad, additional, Dewitte, A., additional, Di Iorio, Biagio R., additional, Di Lullo, Luca, additional, Di Micco, Lucia, additional, Di Nardo, Matteo, additional, Ding, Xiaoqiang, additional, D'Ippoliti, Fiorella, additional, Di Somma, Salvatore, additional, Doi, Kent, additional, Dries, David J., additional, Druml, Wilfred, additional, Duke, Graeme, additional, Durand, Francois, additional, Eadon, Michael T., additional, Eckstein, Devin, additional, Egi, Moritoki, additional, Eiam-Ong, Somchai, additional, Elbers, Paul W.G., additional, Elli, Francesca, additional, Elliott, Steve, additional, Emlet, David R., additional, Endre, Zoltan, additional, Evans, Roger G., additional, Fanelli, Vito, additional, Fattahi, Fatemeh, additional, Federspiel, Christine Kinggaard, additional, Ferrada, Marcela A., additional, Ferrari, Fiorenza, additional, Fiaccadori, Enrico, additional, Fiorentino, Marco, additional, Fisher, Caleb, additional, Flessner, Michael F., additional, Formica, Marco, additional, Forni, Lui G., additional, Francoz, Claire, additional, French, Craig, additional, Fuhrman, Dana Y., additional, Fumagalli, Giordano, additional, Galbusera, Miriam, additional, Gallieni, Maurizio, additional, Gammill, Hilary S., additional, Gao, Dayong, additional, Garzotto, Francesco, additional, Gatta, Giuseppe, additional, Genga, Kelly R., additional, Genovesi, Simonetta, additional, Genyk, Yuri S., additional, Geradin, Christel, additional, Gesualdo, Loreto, additional, Giavarina, Davide, additional, Giuliani, Anna, additional, Glezerman, Ilya G., additional, Goldstein, Stuart L., additional, Golper, Thomas A., additional, Gómez, Hernando, additional, Granata, Antonio, additional, Grandaliano, Giuseppe, additional, Grasselli, Giacomo, additional, Groeneveld, A.B. Johan, additional, Guerci, Philippe, additional, Gunnerson, Kyle J., additional, Harbord, Nikolas, additional, Harshman, Lyndsay A., additional, Hennessy, Anthony J., additional, Hill, Graham L., additional, Hobson, Charles, additional, Hohenstein, Bernd, additional, Honoré, Patrick M., additional, Horwitz, Edward, additional, Hosseinian, Leila, additional, Hoste, Eric A.J., additional, House, Andrew A., additional, Humes, H. David, additional, Husain-Syed, Faeq, additional, Ince, Can, additional, Ing, Todd S., additional, Jacobs, Rita, additional, Jaswal, Dharmvir, additional, Jeyabalan, Arun, additional, Joannes-Boyau, Olivier, additional, Joannidis, Michael, additional, Joyce, Emily, additional, Kane-Gill, Sandra L., additional, Kaplan, Lewis J., additional, Kashani, Kianoush, additional, Katz, Nevin, additional, Kellum, John A., additional, Khanna, Ramesh, additional, Kim-Campbell, Nahmah, additional, King, Joshua D., additional, Kirwan, Christopher J., additional, Kiss, Joseph E., additional, Klein, David, additional, Kotanko, Peter, additional, Krediet, Raymond T., additional, Kuhlmann, Martin K., additional, Kuiper, Jan Willem, additional, Lachance, Philippe, additional, Lameire, Norbert, additional, Langer, Thomas, additional, Lankadeva, Yugeesh R., additional, Laurin, Louis-Philippe, additional, Lazzeri, Elena, additional, Leblanc, Martine, additional, Lefebvre, Joannie, additional, Lentini, Paolo, additional, Leray-Moragués, Hélène, additional, Levin, Adeera, additional, Lew, Susie Q., additional, Liapis, Helen, additional, Liu, Kathleen D., additional, Livigni, Sergio, additional, Locatelli, Francesco, additional, Lorenzin, Anna, additional, Lu, Jian-Da, additional, Lu, Renhua, additional, Lysak, Nicholas, additional, Macedo, Etienne, additional, Madan, Niti, additional, Madore, François, additional, Maerz, Linda L., additional, Maiden, Matthew J., additional, Malhotra, Rakesh, additional, Marengo, Marita, additional, Mariano, Filippo, additional, Marik, Paul E., additional, Marini, John J., additional, Marino, Rossella, additional, Marshall, Mark R., additional, Mårtensson, Johan, additional, Matsuura, Ryo, additional, May, Clive N., additional, Mazzone, Patrizio, additional, McCauley, Jerry, additional, McCullough, Peter A., additional, McMahon, Blaithin A., additional, Mehta, Ravindra L., additional, Mele, Caterina, additional, Menon, Madhav, additional, Meola, Mario, additional, Mérouani, Aicha, additional, Meuwly, Jean-Yves, additional, Milla, Paola, additional, Misra, Madhukar, additional, Misra, Paraish S., additional, Mizock, Barry A., additional, Modi, Jwalant R., additional, Moeckel, Gilbert, additional, Molitoris, Bruce A., additional, Morabito, Santo, additional, Mucelli, Roberto Pozzi, additional, Murray, Patrick T., additional, Murugan, Raghavan, additional, Nadim, Mitra K., additional, Nair, Devika, additional, Nalesso, Federico, additional, Neri, Mauro, additional, Nguyen, Trung C., additional, Ni, Zhaohui, additional, Noris, Marina, additional, Novick, Tessa, additional, O'Horo, John C., additional, Okusa, Mark Douglas, additional, Opal, Steven M., additional, Opdam, Helen Ingrid, additional, Ostermann, Marlies, additional, Ottaviano, Emerenziana, additional, Oudemans-van Straaten, Heleen M., additional, Overgaard-Steensen, Christian, additional, Padalino, Massimo A., additional, Panichi, Vincenzo, additional, Parameswaran, Priyanka, additional, Patel, Samir S., additional, Payen, Didier, additional, Pea, Federico, additional, Peacock, W. Frank, additional, Peart, Sandrica Young, additional, Peerapornratana, Sadudee, additional, Pelosi, Paolo, additional, Peng, Zhi-Yong, additional, Perico, Norberto, additional, Peruzzi, Licia, additional, Pesce, Francesco, additional, Pesenti, Antonio, additional, Petrucci, Ilaria, additional, Pham, Phuong-Chi, additional, Pham, Phuong-Thu, additional, Phoon, Richard K.S., additional, Piano, Salvatore, additional, Pinsky, Michael R., additional, Piquilloud, Lise, additional, Pistolesi, Valentina, additional, Plank, Lindsay D., additional, Plötz, Frans B., additional, Podestá, Manuel Alfredo, additional, Porta, Camillo, additional, Pozzato, Marco, additional, Prencipe, Michele, additional, Prowle, John R., additional, Puthucheary, Zudin A., additional, Qu, Lirong, additional, Rachoin, Jean-Sebastien, additional, Radhakrishnan, Jai, additional, Ranieri, V. Marco, additional, Ratanarat, Ranistha, additional, Remuzzi, Giuseppe, additional, Resnick, Shelby, additional, Rewa, Oleksa G., additional, Ricci, Zaccaria, additional, Ridel, Christophe, additional, Rifai, Kinan, additional, Ring, Troels, additional, Rizo-Topete, Lilia M., additional, Roessler, Eric, additional, Romagnani, Paola, additional, Romagnoli, Stefano, additional, Ronco, Claudio, additional, Ronco, Federico, additional, Rosner, Mitchell H., additional, Rossetti, Emanuele, additional, Russell, James A., additional, Saab, Georges, additional, Sabatino, Alice, additional, Saboo, Sonali S., additional, Samoni, Sara, additional, Sappington, Penny Lynn, additional, Sartori, Marco, additional, Savige, Judy, additional, Schena, Francesco Paolo, additional, Schneider, Antoine Guillaume, additional, Schraverus, Pieter, additional, Schulte, Wibke, additional, Segoloni, Giuseppe, additional, Semler, Matthew W., additional, Sharma, Aashish, additional, Shaw, Andrew, additional, Sheth, Naitik, additional, Shukla, Ashutosh, additional, Siddall, Eric C., additional, Sievers, Theodore M., additional, Siew, Edward D., additional, Singbartl, Kai, additional, Singer, Mervyn, additional, Singh, Pooja, additional, Smith, Loren E., additional, Soni, Sachin S., additional, Soto, Mara Serrano, additional, Spapen, Herbert D., additional, Srisawat, Nattachai, additional, Srivastava, Ajay, additional, Stellin, Giovanni, additional, Symons, Jordan M., additional, Szamosfalvi, Balazs, additional, Tai, Kian Bun, additional, Takalkar, Unmesh V., additional, Teitelbaum, Isaac, additional, Tetta, Ciro, additional, Thakar, Charuhas V., additional, Tonon, Marta, additional, Trepiccione, Francesco, additional, Triulzi, Darrell, additional, Tushar, Chopra, additional, Uchino, Shigehiko, additional, Valika, Ali, additional, Van Biesen, Wim, additional, Vandenberghe, Wim, additional, Vanholder, Raymond, additional, Vanmassenhove, Jill, additional, Verbine, Anton, additional, Vergano, Marco, additional, Villa, Gianluca, additional, Villeneuve, Pierre-Marc, additional, Vincent, Jean-Louis, additional, Vinsonneau, Christophe, additional, Virzì, Grazia Maria, additional, Visconti, Federico, additional, Visvanathan, Ravindran, additional, Van Vong, Li, additional, Walmrath, Hans-Dieter, additional, Ward, Peter A., additional, Weir, Matthew A., additional, Wen, Xiaoyan, additional, Wendon, Julia, additional, Winchester, James Frank, additional, Wong, Adrian, additional, Woodhouse, Elke L., additional, Xue, Jun, additional, Yadav, Anju, additional, Yerram, Preethi, additional, Yessayan, Lenar, additional, Yeun, Jane Y., additional, Yu, Alex W., additional, Zaccaria, Marta, additional, Zacchia, Miriam, additional, Zachariah, Teena P., additional, Zamperetti, Nereo, additional, Zampieri, Fernando G., additional, Zanco, Pierluigi, additional, Zanella, Alberto, additional, Zanoli, Luca, additional, Zappitelli, Michael, additional, Zaragoza, Jose J., additional, Zarbock, Alexander, additional, Zaroccolo, Marta, additional, Zhang, Han, additional, and Zimmer, Andrea, additional

Published
2019
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6. Current role of ultrasound in hemodialysis access evaluation

Author

Jose Ibeas, Jan Malik, and Meola Mario

Subjects
B-Mode and pulsed wave Doppler, Vascular access, point of care of ultrasound, ultrasound instrumentation, vascular access surveillance, medicine.medical_specialty, Standardization, medicine.medical_treatment, 030232 urology & nephrology, Physical examination, 030204 cardiovascular system & hematology, Nephrologists, 03 medical and health sciences, 0302 clinical medicine, Arteriovenous Shunt, Surgical, Renal Dialysis, Original Research Articles, Medicine, Humans, Turning point, Intensive care medicine, Physical Examination, Dialysis, Hemodialysis access, Point of care, Ultrasonography, medicine.diagnostic_test, business.industry, Ultrasound, Nephrology, Surgery, business
Abstract

Physical examination (PE) is considered the backbone before vascular access (VA) placement, during maturation period and for follow-up. However, it may be inadequate in identifying suitable vasculature, mainly in comorbid patients, or in detecting complications. This review highlights the advantages of ultrasound imaging to manage VA before placement, during maturation and follow-up. Furthermore, it analyses the future perspectives in evaluating early and late VA complications thank to the availability of multiparametric platforms, point of care of ultrasound, and portable/wireless systems. Technical improvements and low-cost systems should favor the widespread ultrasound-based VA surveillance programs. This significant turning point needs an adequate training of nephrologists and dialysis nurses and the standardization of exams, parameters, and procedures.

Published
2021

28. Ultrasonographic Intraparenchymal Renal Resistive Index Variation for Assessing Renal Functional Reserve in Patients Scheduled for Cardiac Surgery: A Pilot Study

Author

Samoni, Sara, primary, Villa, Gianluca, additional, De Rosa, Silvia, additional, Husain-Syed, Faeq, additional, Guglielmetti, Gabriele, additional, Tofani, Lorenzo, additional, De Cal, Massimo, additional, Nalesso, Federico, additional, Meola, Mario, additional, and Ronco, Claudio, additional

Published
2021
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31. Ultrasonographic Intraparenchymal Renal Resistive Index Variation for Assessing Renal Functional Reserve in Patients Scheduled for Cardiac Surgery: A Pilot Study.

Author

Samoni, Sara, Villa, Gianluca, De Rosa, Silvia, Husain-Syed, Faeq, Guglielmetti, Gabriele, Tofani, Lorenzo, De Cal, Massimo, Nalesso, Federico, Meola, Mario, and Ronco, Claudio

Subjects
CARDIAC surgery, ELECTIVE surgery, CARDIAC patients, ACUTE kidney failure, RECEIVER operating characteristic curves, LOGISTIC regression analysis
Abstract

Introduction: Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication in patients undergoing cardiac surgery. Preoperative renal functional reserve (RFR) has been demonstrated to be highly predictive of CSA-AKI. We have previously demonstrated that intraparenchymal renal resistive index variation (IRRIV) measured by ultrasound (US) can identify the presence of RFR in healthy individuals. This study aimed (1) to examine the correlation between the US IRRIV test and RFR measured through the protein loading test in patients undergoing elective cardiac surgery and (2) to determine the value of the 2 methods for predicting occurrence of AKI or subclinical AKI after cardiac surgery. Methods: Consecutive patients scheduled for cardiac surgery were enrolled for this pilot study. The protein loading test and the IRRIV test were performed in all patients 2 days before cardiac surgery. Correlation between IRRIV and RFR was tested using Pearson correlation analysis. Association between presence of RFR and positive IRRIV test, presence of RFR and AKI and subclinical AKI, and positive IRRIV test and AKI and subclinical AKI was evaluated using logistic regression analysis. Receiver operating characteristic (ROC) curve analysis was performed to evaluate the values of IRRIV for predicting RFR, RFR for predicting AKI and subclinical AKI, and IRRIV for predicting AKI and subclinical AKI. Results: Among the 31 patients enrolled, significant association was found between IRRIV and RFR (r = 0.81; 95% CI: 0.63–0.90; p < 0.01). The association between RFR and IRRIV was described in 27/31 (87.1%) patients. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the IRRIV test were 100, 84, 60, and 100%, respectively. In ROC curve analysis, the area under the curve (AUC) was 0.80 (95% CI: 0.64–0.96). After cardiac surgery, 1/31 (3.2%) patient had AKI and 12/31 (38.7%) had subclinical AKI. RFR predicted subclinical AKI (odds ratio [OR] = 0.93; 95% CI: 0.87–0.98; p = 0.02). The sensitivity, specificity, PPV, and NPV of the RFR were 61, 88.8, 80, and 76%, respectively; the AUC was 0.75 (95% CI: 0.59–0.91). IRRIV predicts subclinical AKI (OR = 0.79; 95% CI: 0.67–0.93; p = 0.005). The sensitivity, specificity, PPV, and NPV of the IRRIV test were 46.1, 100, 100, and 72%, respectively; the AUC was 0.73 (95% CI: 0.58–0.87). Conclusion: This pilot study suggests that a positive IRRIV test can significantly predict the presence of RFR in patients scheduled for cardiac surgery. RFR measured by the protein loading test or by the US IRRIV test can predict the occurrence of subclinical postoperative AKI. The findings of this study need to be confirmed in large patient cohorts. [ABSTRACT FROM AUTHOR]

Published
2022
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36. The Pisa experience of renal biopsies, 1977-2005

Author

Panichi, Vincenzo, Pasquariello, Antonio, Innocenti, Maurizio, Meola, Mario, Mantuano, Emanuela, Beati, Sara, Paoletti, Sabrina, Consani, Cristina, Puccini, Rodolfo, Casarosa, Leonardo, Gattai, Vittorio, Filippi, Cristina, Moriconi, Luigi, Barsotti, Giuliano, Rindi, Paolo, and Palla, Roberto

Published
2007

40. [The Retroperitoneal space]

Author

Mancini, Andrea, Meola, Mario, Tarantino, Giuseppe, Petrucci, Ilaria, Berardi, Giovanna, and Cuzzola, Cristoforo

Subjects
hydronephrosis, retroperitoneal fibrosis, retroperitoneal space, urinoma, Female, Humans, Hydronephrosis, Middle Aged, Retroperitoneal Fibrosis, Retroperitoneal Space
Published
2017

43. Colaboradores

Author

Albright, Robert C., Amerling, Richard, Angeli, Paolo, Lucia Angelotti, Maria, Antonelli, Massimo, Antoniotti, Riccardo, Arulkumaran, Nishkantha, Asfar, Pierre, Ash, Stephen R., Aucella, Filippo, Aucella, Francesco, Ave, Samuele, Bagshaw, Sean M., Balaraman, Vasanthi, Baldwin, Ian, Bargman, Joanne M., Barletta, Gina-Marie, Barletta, Jeffrey F., Barnela, Shriganesh R., Bayır, Hülya, Beaulieu, Monica, Bellasi, Antonio, Bellomo, Rinaldo, Beloncle, François, Bhansali, Arjun, Bihorac, Azra, Billings, Frederic T., Birk, Horst-Walter, Bonilla-Reséndiz, Luis Ignacio, Bouchard, Josée, Bourke, Edmund, Braitberg, George, Brendolan, Alessandra, Brocca, Alessandra, Brophy, Patrick D., Bucala, Richard, Bunchman, Timothy E., Burdmann, Emmanuel A., Busse, Laurence W., Antunes Caires, Renato, Caironi, Pietro, Camilla, Roberta, Campos, Israel, Canaud, Bernard, Cantaluppi, Vincenzo, Martinez Cantarin, Maria P., Capasso, Giovambattista, Carcillo, Joseph A., Carlesso, Eleonora, Casino, Francesco G., Castellano, Giuseppe, Catania, Matteo, Cawcutt, Kelly A., Cerda, Jorge, Charen, Elliot, Chawla, Lakhmir S., Chiaramonte, Stefano, Chua, Horng-Ruey, Cianciaruso, Bruno, Ciceri, Paola, Cieslak, Jacek, Clark, William R., Claure-Del Granado, Rolando, Clementi, Anna, Co, Ivan N., Oliveira Coelho, Fernanda, Conte, Ferruccio, Corey, Howard E., Cosmai, Laura, Carlos Costalonga, Elerson, Costamagna, Andrea, Rosa Costanzo, Maria, Cozzolino, Mario, Cramer, Carl H., Cravedi, Paolo, Crepaldi, Carlo, Creteur, Jacques, John Crew, R., Torres da Costa Silva, Verônica, Davenport, Andrew, Davies, Andrew R., D’Costa, Rohit, Dean, Dawson F., Debiais, Charlotte, de Cal, Massimo, Dedhia, Paras, de Grooth, Harm-Jan, Dell’Aquila, Roberto, Dellepiane, Sergio, Phillip Dellinger, Richard, Del Vecchio, Lucia, Depner, Thomas A., De Rosa, Silvia, Deutschman, Clifford S., Devarajan, Prasad, Dewitte, A., Di Iorio, Biagio R., Di Lullo, Luca, Di Micco, Lucia, Di Nardo, Matteo, Ding, Xiaoqiang, D’Ippoliti, Fiorella, Di Somma, Salvatore, Doi, Kent, Dries, David J., Druml, Wilfred, Duke, Graeme, Durand, Francois, Eadon, Michael T., Eckstein, Devin, Egi, Moritoki, Eiam-Ong, Somchai, Elbers, Paul W.G., Elli, Francesca, Elliott, Steve, Emlet, David R., Endre, Zoltan, Evans, Roger G., Fanelli, Vito, Fattahi, Fatemeh, Kinggaard Federspiel, Christine, Ferrada, Marcela A., Ferrari, Fiorenza, Fiaccadori, Enrico, Fiorentino, Marco, Fisher, Caleb, Flessner, Michael F., Formica, Marco, Forni, Lui G., Francoz, Claire, French, Craig, Fuhrman, Dana Y., Fumagalli, Giordano, Galbusera, Miriam, Gallieni, Maurizio, Gammill, Hilary S., Gao, Dayong, Garzotto, Francesco, Gatta, Giuseppe, Genga, Kelly R., Genovesi, Simonetta, Genyk, Yuri S., Geradin, Christel, Gesualdo, Loreto, Giavarina, Davide, Giuliani, Anna, Glezerman, Ilya G., Goldstein, Stuart L., Golper, Thomas A., Gómez, Hernando, Granata, Antonio, Grandaliano, Giuseppe, Grasselli, Giacomo, Johan Groeneveld, A.B., Guerci, Philippe, Gunnerson, Kyle J., Harbord, Nikolas, Harshman, Lyndsay A., Hennessy, Anthony J., Hill, Graham L., Hobson, Charles, Hohenstein, Bernd, Honoré, Patrick M., Horwitz, Edward, Hosseinian, Leila, Hoste, Eric A.J., House, Andrew A., David Humes, H., Husain-Syed, Faeq, Ince, Can, Ing, Todd S., Jacobs, Rita, Jaswal, Dharmvir, Jeyabalan, Arun, Joannes-Boyau, Olivier, Joannidis, Michael, Joyce, Emily, Kane-Gill, Sandra L., Kaplan, Lewis J., Kashani, Kianoush, Katz, Nevin, Kellum, John A., Khanna, Ramesh, Kim-Campbell, Nahmah, King, Joshua D., Kirwan, Christopher J., Kiss, Joseph E., Klein, David, Kotanko, Peter, Krediet, Raymond T., Kuhlmann, Martin K., Willem Kuiper, Jan, Lachance, Philippe, Lameire, Norbert, Langer, Thomas, Lankadeva, Yugeesh R., Laurin, Louis-Philippe, Lazzeri, Elena, Leblanc, Martine, Lefebvre, Joannie, Lentini, Paolo, Leray-Moragués, Hélène, Levin, Adeera, Lew, Susie Q., Liapis, Helen, Liu, Kathleen D., Livigni, Sergio, Locatelli, Francesco, Lorenzin, Anna, Lu, Jian-Da, Lu, Renhua, Lysak, Nicholas, Macedo, Etienne, Madan, Niti, Madore, François, Maerz, Linda L., Maiden, Matthew J., Malhotra, Rakesh, Marengo, Marita, Mariano, Filippo, Marik, Paul E., Marini, John J., Marino, Rossella, Marshall, Mark R., Mårtensson, Johan, Matsuura, Ryo, May, Clive N., Mazzone, Patrizio, McCauley, Jerry, McCullough, Peter A., McMahon, Blaithin A., Mehta, Ravindra L., Mele, Caterina, Menon, Madhav, Meola, Mario, Mérouani, Aicha, Meuwly, Jean-Yves, Milla, Paola, Misra, Madhukar, Misra, Paraish S., Mizock, Barry A., Modi, Jwalant R., Moeckel, Gilbert, Molitoris, Bruce A., Morabito, Santo, Pozzi Mucelli, Roberto, Murray, Patrick T., Murugan, Raghavan, Nadim, Mitra K., Nair, Devika, Nalesso, Federico, Neri, Mauro, Nguyen, Trung C., Ni, Zhaohui, Noris, Marina, Novick, Tessa, O’Horo, John C., Douglas Okusa, Mark, Opal, Steven M., Ingrid Opdam, Helen, Ostermann, Marlies, Ottaviano, Emerenziana, Oudemans-van Straaten, Heleen M., Overgaard-Steensen, Christian, Padalino, Massimo A., Panichi, Vincenzo, Parameswaran, Priyanka, Patel, Samir S., Payen, Didier, Pea, Federico, Frank Peacock, W., Young Peart, Sandrica, Peerapornratana, Sadudee, Pelosi, Paolo, Peng, Zhi-Yong, Perico, Norberto, Peruzzi, Licia, Pesce, Francesco, Pesenti, Antonio, Petrucci, Ilaria, Pham, Phuong-Chi, Pham, Phuong-Thu, Phoon, Richard K.S., Piano, Salvatore, Pinsky, Michael R., Piquilloud, Lise, Pistolesi, Valentina, Plank, Lindsay D., Plötz, Frans B., Alfredo Podestá, Manuel, Porta, Camillo, Pozzato, Marco, Prencipe, Michele, Prowle, John R., Puthucheary, Zudin A., Qu, Lirong, Rachoin, Jean-Sebastien, Radhakrishnan, Jai, Marco Ranieri, V., Ratanarat, Ranistha, Remuzzi, Giuseppe, Resnick, Shelby, Rewa, Oleksa G., Ricci, Zaccaria, Ridel, Christophe, Rifai, Kinan, Ring, Troels, Rizo-Topete, Lilia M., Roessler, Eric, Romagnani, Paola, Romagnoli, Stefano, Ronco, Claudio, Ronco, Federico, Rosner, Mitchell H., Rossetti, Emanuele, Russell, James A., Saab, Georges, Sabatino, Alice, Saboo, Sonali S., Samoni, Sara, Lynn Sappington, Penny, Sartori, Marco, Savige, Judy, Paolo Schena, Francesco, Guillaume Schneider, Antoine, Schraverus, Pieter, Schulte, Wibke, Segoloni, Giuseppe, Semler, Matthew W., Sharma, Aashish, Shaw, Andrew, Sheth, Naitik, Shukla, Ashutosh, Siddall, Eric C., Sievers, Theodore M., Siew, Edward D., Singbartl, Kai, Singer, Mervyn, Singh, Pooja, Smith, Loren E., Soni, Sachin S., Serrano Soto, Mara, Spapen, Herbert D., Srisawat, Nattachai, Srivastava, Ajay, Stellin, Giovanni, Symons, Jordan M., Szamosfalvi, Balazs, Bun Tai, Kian, Takalkar, Unmesh V., Teitelbaum, Isaac, Tetta, Ciro, Thakar, Charuhas V., Tonon, Marta, Trepiccione, Francesco, Triulzi, Darrell, Tushar, Chopra, Uchino, Shigehiko, Valika, Ali, Van Biesen, Wim, Vandenberghe, Wim, Vanholder, Raymond, Vanmassenhove, Jill, Verbine, Anton, Vergano, Marco, Villa, Gianluca, Villeneuve, Pierre-Marc, Vincent, Jean-Louis, Vinsonneau, Christophe, Maria Virzì, Grazia, Visconti, Federico, Visvanathan, Ravindran, Van Vong, Li, Walmrath, Hans-Dieter, Ward, Peter A., Weir, Matthew A., Wen, Xiaoyan, Wendon, Julia, Frank Winchester, James, Wong, Adrian, Woodhouse, Elke L., Xue, Jun, Yadav, Anju, Yerram, Preethi, Yessayan, Lenar, Yeun, Jane Y., Yu, Alex W., Zaccaria, Marta, Zacchia, Miriam, Zachariah, Teena P., Zamperetti, Nereo, Zampieri, Fernando G., Zanco, Pierluigi, Zanella, Alberto, Zanoli, Luca, Zappitelli, Michael, Zaragoza, Jose J., Zarbock, Alexander, Zaroccolo, Marta, Zhang, Han, and Zimmer, Andrea

Published
2020
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45. Intra-Parenchymal Renal Resistive Index Variation (IRRIV) Describes Renal Functional Reserve (RFR): Pilot Study in Healthy Volunteers

Author

Samoni, Sara, Nalesso, Federico, Meola, Mario, Villa, Gianluca, De Cal, Massimo, De Rosa, Silvia, Petrucci, Ilaria, Brendolan, Alessandra, Rosner, Mitchell H., and Ronco, Claudio

Subjects
renal hemodynamics, color doppler, healthy volunteers, Physiology, renal resistive index (RRI), protein loading test, renal blood flow, renal functional reserve (RFR), intra-parenchymal renal resistive index variation (IRRIV)
Abstract

An increase of glomerular filtration rate after protein load represents renal functional reserve (RFR) and is due to afferent arteriolar vasodilation. Lack of RFR may be a risk factor for acute kidney injury (AKI), but is cumbersome to measure. We sought to develop a non-invasive, bedside method that would indirectly measure RFR. Mechanical abdominal pressure, through compression of renal vessels, decreases blood flow and activates the auto-regulatory mechanism which can be measured by a fall in renal resistive index (RRI). The study aims at elucidating the relationship between intra-parenchymal renal resistive index variation (IRRIV) during abdominal pressure and RFR. In healthy volunteers, pressure was applied by a weight on the abdomen (fluid-bag 10% of subject's body weight) while RFR was measured through a protein loading test. We recorded RRI in an interlobular artery after application of pressure using ultrasound. The maximum percentage reduction of RRI from baseline was compared in the same subject to RFR. We enrolled 14 male and 16 female subjects (mean age 38 ± 14 years). Mean creatinine clearance was 106.2 ± 16.4 ml/min/1.73 m2. RFR ranged between −1.9 and 59.7 with a mean value of 28.9 ± 13.1 ml/min/1.73 m2. Mean baseline RRI was 0.61 ± 0.05, compared to 0.49 ± 0.06 during abdominal pressure; IRRIV was 19.6 ± 6.7%, ranging between 3.1% and 29.2%. Pearson's coefficient between RFR and IRRIV was 74.16% (p < 0.001). Our data show the correlation between IRRIV and RFR. Our results can lead to the development of a “stress test” for a rapid screen of RFR to establish renal susceptibility to different exposures and the consequent risk for AKI.

Published
2016
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