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7 results on '"Menidjel, Reyene"'

1. Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response

Author

Manet, Caroline, Mansuroglu, Zeyni, Conquet, Laurine, Bortolin, Violaine, Comptdaer, Thomas, Segrt, Helena, Bourdon, Marie, Menidjel, Reyene, Stadler, Nicolas, Tian, Guanfang, Herit, Floriane, Niedergang, Florence, Souès, Sylvie, Buée, Luc, Galas, Marie-Christine, Montagutelli, Xavier, and Bonnefoy, Eliette

Published
2022
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2. High sera levels of SARS‐CoV‐2 N antigen are associated with death in hospitalized COVID‐19 patients.

Author

Chenane, Houssem Redha, Lingas, Guillaume, Menidjel, Reyene, Laouenan, Cédric, Tubiana, Sarah, Descamps, Diane, Le Hingrat, Quentin, Abel, Laurent, Guedj, Jérémie, Malhotra, Surbhi, Kumar‐Singh, Samir, Visseaux, Benoit, Ghosn, Jade, Charpentier, Charlotte, and Lebourgeois, Samuel

Subjects
SARS-CoV-2, COVID-19, HOSPITAL patients
Abstract

The presence of free severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) nucleocapsid‐antigen in sera (N‐antigenemia) has been shown in COVID‐19 patients. However, the link between the quantitative levels of N‐antigenemia and COVID‐19 disease severity is not entirely understood. To assess the dynamics and clinical association of N‐antigen sera levels with disease severity in COVID‐19 patients, we analyzed data from patients included in the French COVID cohort, with at least one sera sample between January and September 2020. We assessed N‐antigenemia levels and anti‐N IgG titers, and patient outcomes was classified in two groups, survival or death. In samples collected within 8 days since symptom onset, we observed that deceased patients had a higher positivity rate (93% vs. 81%; p < 0.001) and higher median levels of predicted N‐antigenemia (2500 vs. 1200 pg/mL; p < 0.001) than surviving patients. Predicted time to N‐antigen clearance in sera was prolonged in deceased patients compared to survivors (23.3 vs 19.3 days; p < 0.0001). In a subset of patients with both sera and nasopharyngeal (NP) swabs, predicted time to N‐antigen clearance in sera was prolonged in deceased patients (p < 0.001), whereas NP viral load clearance did not differ between the groups (p = 0.07). Our results demonstrate a strong relationship between N‐antigenemia levels and COVID‐19 severity on a prospective cohort. [ABSTRACT FROM AUTHOR]

Published
2023
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3. Differential activation of human neutrophils by SARS-CoV-2 variants of concern

Author

Lebourgeois, Samuel, primary, David, Ambroise, additional, Chenane, Houssem Redha, additional, Granger, Vanessa, additional, Menidjel, Reyene, additional, Fidouh, Nadhira, additional, Noël, Benoît, additional, Delelis, Olivier, additional, Richetta, Clémence, additional, Charpentier, Charlotte, additional, Chollet-Martin, Sylvie, additional, Descamps, Diane, additional, Visseaux, Benoit, additional, and de Chaisemartin, Luc, additional

Published
2022
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5. Alpha (B.1.1.7) and Delta (B.1.617.2 – AY.40) SARS-CoV-2 variants present strong neutralization decay at M4 post-vaccination and a faster replication rates than D614G (B.1) lineage

Author

Lebourgeois, Samuel, primary, Menidjel, Reyene, additional, Chenane, Houssem Redha, additional, Ferré, Valentine Marie, additional, Collin, Gilles, additional, Damond, Florence, additional, Coppée, Romain, additional, Yazdanpanah, Yazdan, additional, Timsit, Jean-François, additional, Houhou-Fidouh, Nadhira, additional, Descamps, Diane, additional, Charpentier, Charlotte, additional, and Visseaux, Benoit, additional

Published
2022
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6. Decreasing humoral response among healthcare workers up to 4 months after two doses of BNT162b2 vaccine

Author

Ferré, Valentine Marie, primary, Lebourgeois, Samuel, additional, Menidjel, Reyene, additional, Collin, Gilles, additional, Chenane, Houssem Redha, additional, Guindi, Manuella Onambele, additional, Yazdanpanah, Yazdan, additional, Timsit, Jean-François, additional, Charpentier, Charlotte, additional, Descamps, Diane, additional, Fidouh, Nadhira, additional, and Visseaux, Benoit, additional

Published
2022
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7. Earlier In Vitro Viral Production With SARS-CoV-2 Alpha Than With Beta, Gamma, B, or A.27 Variants

Author

Lebourgeois, Samuel, primary, Chenane, Houssem Redha, additional, Houhou-Fidouh, Nadhira, additional, Menidjel, Reyene, additional, Ferré, Valentine Marie, additional, Collin, Gilles, additional, Benmalek, Nabil, additional, Coppée, Romain, additional, Larrouy, Lucile, additional, Yazdanpanah, Yazdan, additional, Timsit, Jean-François, additional, Charpentier, Charlotte, additional, Descamps, Diane, additional, and Visseaux, Benoit, additional

Published
2021
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