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2. Correction to: Parma consensus statement on metabolic disruptors.

Author

Heindel, Jerrold J, Vom Saal, Frederick S, Blumberg, Bruce, Bovolin, Patrizia, Calamandrei, Gemma, Ceresini, Graziano, Cohn, Barbara A, Fabbri, Elena, Gioiosa, Laura, Kassotis, Christopher, Legler, Juliette, La Merrill, Michele, Rizzi, Laura, Machtinger, Ronit, Mantovani, Alberto, Mendez, Michelle A, Montanini, Luisa, Molteni, Laura, Nagel, Susan C, Parmigiani, Stefano, Panzica, Giancarlo, Paterlini, Silvia, Pomatto, Valentina, Ruzzin, Jérôme, Sartor, Giorgio, Schug, Thaddeus T, Street, Maria E, Suvorov, Alexander, Volpi, Riccardo, Zoeller, R Thomas, and Palanza, Paola

Subjects
Toxicology, Public Health and Health Services
Abstract

CorrectionAfter publication of the article [1], it has been brought to our attention that the thirteenth author of this article has had their name spelt incorrectly. In the original article the spelling "Laura Rizzir" was used. In fact the correct spelling should be "Laura Rizzi".

Published
2017

4. Metabolism disrupting chemicals and metabolic disorders

Author

Heindel, Jerrold J, Blumberg, Bruce, Cave, Mathew, Machtinger, Ronit, Mantovani, Alberto, Mendez, Michelle A, Nadal, Angel, Palanza, Paola, Panzica, Giancarlo, Sargis, Robert, Vandenberg, Laura N, and Saal, Frederick vom

Subjects
Pharmacology and Pharmaceutical Sciences, Reproductive Medicine, Biomedical and Clinical Sciences, Chronic Liver Disease and Cirrhosis, Diabetes, Rare Diseases, Estrogen, Genetics, Nutrition, Digestive Diseases, Prevention, Liver Disease, Obesity, Aetiology, 2.1 Biological and endogenous factors, 2.2 Factors relating to the physical environment, Oral and gastrointestinal, Metabolic and endocrine, Good Health and Well Being, Animals, Endocrine Disruptors, Female, Humans, Metabolic Diseases, Metabolic Networks and Pathways, Neurosecretory Systems, Pregnancy, Prenatal Exposure Delayed Effects, Sex Characteristics, Endocrine disruptors, Obesogens, Metabolism disruptors, Developmental origins of health and disease, Lipid disorders, Paediatrics and Reproductive Medicine, Public Health and Health Services, Toxicology, Pharmacology and pharmaceutical sciences, Reproductive medicine
Abstract

The recent epidemics of metabolic diseases, obesity, type 2 diabetes(T2D), liver lipid disorders and metabolic syndrome have largely been attributed to genetic background and changes in diet, exercise and aging. However, there is now considerable evidence that other environmental factors may contribute to the rapid increase in the incidence of these metabolic diseases. This review will examine changes to the incidence of obesity, T2D and non-alcoholic fatty liver disease (NAFLD), the contribution of genetics to these disorders and describe the role of the endocrine system in these metabolic disorders. It will then specifically focus on the role of endocrine disrupting chemicals (EDCs) in the etiology of obesity, T2D and NAFLD while finally integrating the information on EDCs on multiple metabolic disorders that could lead to metabolic syndrome. We will specifically examine evidence linking EDC exposures during critical periods of development with metabolic diseases that manifest later in life and across generations.

Published
2017

5. Short-term planning and policy interventions to promote cycling in urban centers: Findings from a commute mode choice analysis in Barcelona, Spain

Author

Braun, Lindsay M, Rodriguez, Daniel A, Cole-Hunter, Tom, Ambros, Albert, Donaire-Gonzalez, David, Jerrett, Michael, Mendez, Michelle A, Nieuwenhuijsen, Mark J, and de Nazelle, Audrey

Subjects
Cardiovascular, Quality Education, Sustainable Cities and Communities, Cycling, Infrastructure, Policy, Programs, Bike share, Built environment, Urban and Regional Planning, Transportation and Freight Services, Logistics & Transportation
Abstract

Background: Cycling for transportation has become an increasingly important component of strategies to address public health, climate change, and air quality concerns in urban centers. Within this context, planners and policy makers would benefit from an improved understanding of available interventions and their relative effectiveness for cycling promotion. We examined predictors of bicycle commuting that are relevant to planning and policy intervention, particularly those amenable to short- and medium-term action. Methods: We estimated a travel mode choice model using data from a survey of 765 commuters who live and work within the municipality of Barcelona. We considered how the decision to commute by bicycle was associated with cycling infrastructure, bike share availability, travel demand incentives, and other environmental attributes (e.g., public transport availability). Self-reported and objective (GIS-based) measures were compared. Point elasticities and marginal effects were calculated to assess the relative explanatory power of the independent variables considered. Results: While both self-reported and objective measures of access to cycling infrastructure were associated with bicycle commuting, self-reported measures had stronger associations. Bicycle commuting had positive associations with access to bike share stations but inverse associations with access to public transport stops. Point elasticities suggested that bicycle commuting has a mild negative correlation with public transport availability (-0.136), bike share availability is more important at the work location (0.077) than at home (0.034), and bicycle lane presence has a relatively small association with bicycle commuting (0.039). Marginal effects suggested that provision of an employer-based incentive not to commute by private vehicle would be associated with an 11.3% decrease in the probability of commuting by bicycle, likely reflecting the typical emphasis of such incentives on public transport. Conclusions: The results provide evidence of modal competition between cycling and public transport, through the presence of public transport stops and the provision of public transport-oriented travel demand incentives. Education and awareness campaigns that influence perceptions of cycling infrastructure availability, travel demand incentives that encourage cycling, and policies that integrate public transport and cycling may be promising and cost-effective strategies to promote cycling in the short to medium term.

Published
2016

6. Parma consensus statement on metabolic disruptors

Author

Heindel, Jerrold J, vom Saal, Frederick S, Blumberg, Bruce, Bovolin, Patrizia, Calamandrei, Gemma, Ceresini, Graziano, Cohn, Barbara A, Fabbri, Elena, Gioiosa, Laura, Kassotis, Christopher, Legler, Juliette, La Merrill, Michele, Rizzir, Laura, Machtinger, Ronit, Mantovani, Alberto, Mendez, Michelle A, Montanini, Luisa, Molteni, Laura, Nagel, Susan C, Parmigiani, Stefano, Panzica, Giancarlo, Paterlini, Silvia, Pomatto, Valentina, Ruzzin, Jérôme, Sartor, Giorgio, Schug, Thaddeus T, Street, Maria E, Suvorov, Alexander, Volpi, Riccardo, Zoeller, R Thomas, and Palanza, Paola

Subjects
Epidemiology, Public Health, Health Sciences, Obesity, Nutrition, 2.1 Biological and endogenous factors, Aetiology, Metabolic and endocrine, Congresses as Topic, Consensus Development Conferences as Topic, Diabetes Mellitus, Environmental Exposure, Environmental Pollutants, Hazardous Substances, Humans, Italy, Metabolic Syndrome, Metabolic disruptor, Obesogen, Diabetes, Metabolic syndrome, Developmental Programming, Public Health and Health Services, Toxicology, Public health
Abstract

A multidisciplinary group of experts gathered in Parma Italy for a workshop hosted by the University of Parma, May 16-18, 2014 to address concerns about the potential relationship between environmental metabolic disrupting chemicals, obesity and related metabolic disorders. The objectives of the workshop were to: 1. Review findings related to the role of environmental chemicals, referred to as "metabolic disruptors", in obesity and metabolic syndrome with special attention to recent discoveries from animal model and epidemiology studies; 2. Identify conclusions that could be drawn with confidence from existing animal and human data; 3. Develop predictions based on current data; and 4. Identify critical knowledge gaps and areas of uncertainty. The consensus statements are intended to aid in expanding understanding of the role of metabolic disruptors in the obesity and metabolic disease epidemics, to move the field forward by assessing the current state of the science and to identify research needs on the role of environmental chemical exposures in these diseases. We propose broadening the definition of obesogens to that of metabolic disruptors, to encompass chemicals that play a role in altered susceptibility to obesity, diabetes and related metabolic disorders including metabolic syndrome.

Published
2015

7. Disinhibition, rather than moderate-to-severe traumatic brain injury, moderates the impact of anger provocation on subjective emotional experience.

Author

Mendez, Michelle, Logan, Jodie, Filipčíková, Michaela, McDonald, Skye, and Wearne, Travis

Subjects
*BRAIN injuries, *EMOTIONAL conditioning, *EMOTION regulation, *HEART beat, *EMOTIONAL experience
Abstract

AbstractObjectiveMethodResultsConclusionsAltered reactivity to emotional stimuli is common after traumatic brain injury (TBI), which is suggested to reflect difficulties with emotion regulation. While disinhibition is common after moderate-to-severe TBI, limited research has investigated the link between disinhibition and emotional reactivity in this clinical group. The aim of this research, therefore, was to investigate the relationship between disinhibition and TBI to anger provocation.Thirty-five individuals with moderate-to-severe TBI and thirty-one controls completed an anger induction task. Participants rated their experience of emotions and subjective arousal before and after the induction. Heart rate, respiration and skin conductance were also measured. Disinhibition was measured using the Frontal Systems Behavior Scale.In the full sample, the mood induction led to increased skin conductance, respiration, and self-reported anger, tension, arousal and negative mood. There were no differences between those with TBI and controls. Disinhibition interacted with the impact of anger provocation on subjective, but not objective, outcomes such that those elevated in disinhibition reported increased feelings of anger and tension in response to the mood induction. Disinhibition did not interact with TBI across any subjective and objective emotional measures examined in response to mood induction.While anger causes emotional changes for all individuals, these changes are particularly pronounced among those who are disinhibited, irrespective of whether an individual has sustained a TBI. This is an important consideration when examining emotional regulation post-TBI as the degree of disinhibition appears to alter subjective interpretations of emotional events, which could lead to emotion dysregulation. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Meat intake, cooking methods and doneness and risk of colorectal tumours in the Spanish multicase-control study (MCC-Spain)

Author

de Batlle, Jordi, Gracia-Lavedan, Esther, Romaguera, Dora, Mendez, Michelle, Castaño-Vinyals, Gemma, Martín, Vicente, Aragonés, Núria, Gómez-Acebo, Inés, Olmedo-Requena, Rocío, Jimenez-Moleon, José Juan, Guevara, Marcela, Azpiri, Mikel, Llorens-Ivorra, Cristóbal, Fernandez-Tardon, Guillermo, Lorca, Jose Andrés, Huerta, José María, Moreno, Victor, Boldo, Elena, Pérez-Gómez, Beatriz, Castilla, Jesús, Fernández-Villa, Tania, Barrio, Juan Pablo, Andreu, Montserrat, Castells, Antoni, Dierssen, Trinidad, Altzibar, Jone M., Kogevinas, Manolis, Pollán, Marina, and Amiano, Pilar

Published
2018
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24. Maternal diet, prenatal exposure to dioxin-like compounds and birth outcomes in a European prospective mother–child study (NewGeneris)

Author

Papadopoulou, Eleni, Kogevinas, Manolis, Botsivali, Maria, Pedersen, Marie, Besselink, Harrie, Mendez, Michelle A., Fleming, Sarah, Hardie, Laura J., Knudsen, Lisbeth E., Wright, John, Agramunt, Silvia, Sunyer, Jordi, Granum, Berit, Gutzkow, Kristine B., Brunborg, Gunnar, Alexander, Jan, Meltzer, Helle Margrete, Brantsæter, Anne Lise, Sarri, Katerina, Chatzi, Leda, Merlo, Domenico F., Kleinjans, Jos C., and Haugen, Margaretha

Published
2014
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33. Body mass index trajectory classes and incident asthma in childhood: Results from 8 European Birth Cohorts—a Global Allergy and Asthma European Network initiative

Author

Rzehak, Peter, Wijga, Alet H., Keil, Thomas, Eller, Esben, Bindslev-Jensen, Carsten, Smit, Henriette A., Weyler, Joost, Dom, Sandra, Sunyer, Jordi, Mendez, Michelle, Torrent, Maties, Vall, Oriol, Bauer, Carl-Peter, Berdel, Dietrich, Schaaf, Beate, Chen, Chih-Mei, Bergström, Anna, Fantini, Maria P., Mommers, Monique, Wahn, Ulrich, Lau, Susanne, and Heinrich, Joachim

Published
2013
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39. Birth Weight, Head Circumference, and Prenatal Exposure to Acrylamide from Maternal Diet: The European Prospective Mother—Child Study (NewGeneris)

Author

NewGeneris Consortium, Pedersen, Marie, von Stedingk, Hans, Botsivali, Maria, Agramunt, Silvia, Alexander, Jan, Brunborg, Gunnar, Chatzi, Leda, Fleming, Sarah, Fthenou, Eleni, Granum, Berit, Gutzkow, Kristine B., Hardie, Laura J., Knudsen, Lisbeth E., Kyrtopoulos, Soterios A., Mendez, Michelle A., Merlo, Domenico F., Nielsen, Jeanette K., Rydberg, Per, Segerbäck, Dan, Sunyer, Jordi, Wright, John, Törnqvist, Margareta, Kleinjans, Jos C., and Kogevinas, Manolis

Published
2012

49. Improving health through policies that promote active travel: A review of evidence to support integrated health impact assessment

Author

de Nazelle, Audrey, Nieuwenhuijsen, Mark J., Antó, Josep M., Brauer, Michael, Briggs, David, Braun-Fahrlander, Charlotte, Cavill, Nick, Cooper, Ashley R., Desqueyroux, Hélène, Fruin, Scott, Hoek, Gerard, Panis, Luc Int, Janssen, Nicole, Jerrett, Michael, Joffe, Michael, Andersen, Zorana Jovanovic, van Kempen, Elise, Kingham, Simon, Kubesch, Nadine, Leyden, Kevin M., Marshall, Julian D., Matamala, Jaume, Mellios, Giorgos, Mendez, Michelle, Nassif, Hala, Ogilvie, David, Peiró, Rosana, Pérez, Katherine, Rabl, Ari, Ragettli, Martina, Rodríguez, Daniel, Rojas, David, Ruiz, Pablo, Sallis, James F., Terwoert, Jeroen, Toussaint, Jean-François, Tuomisto, Jouni, Zuurbier, Moniek, and Lebret, Erik

Published
2011
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