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Objective: To conduct a cross-cultural adaptation and validation in Primary Care of the PREMEPA doctor-patient relationship perception questionnaire., Design: Descriptive, cross-sectional study, using self-administered questionnaires. Qualitative validation: an adapted version of the original questionnaire, was adapted to our culture. The process consisted of the evaluation, cross-cultural adaptation and consensus of a group of experts. The questionnaire was piloted on a sample of 32 patients diagnosed with at least 2 chronic pathologies., Measures: Cognitive piloting, comprehensibility assessment, content validation and internal consistency analysis using Cronbach's alpha coefficient. Quantitative validation: the internal consistency, construct validity and validity of the questionnaire were studied by means of a confirmatory factor analysis developed in a multicenter study, randomly selecting 202 patients with at least 2 chronic pathologies., Results: Content validity of the new Spanish version was confirmed to be adequate. Comprehensibility and internal consistency (Cronbach's α coefficient = 0.78) were adequate. The confirmatory factor analysis showed good dimensionality, factor relationship and internal consistency, as well as acceptable construct validity. The final result was a 13-item questionnaire consisting of 2 dimensions, which explain 58.5% of the variance: participation in decision-making (accounting for 45.2% of the variance) and person-centered communication (encompassing courtesy, empathy, humanity, and trust)., Conclusions: This adapted version of the PREMEPA questionnaire can be considered valid for use in the Spanish population with a history of chronic pathology. This version of PREMEPA provides a new instrument to understand and improve chronic patient care, which can improve the doctor-patient relationship, encouraging adherence to treatment and enhancing health outcomes., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Objectives: Design, construction and validation of a self-completion test that allows the Family Physician (FP) to assess the extent to which he/she integrates person-centred care (PCC) in his/her clinical practice., Design: Qualitative. Questionnaire design., Location: Primary care., Participants: Two hundred and fourteen family and community medicine physicians and residents, from 62 of the 80 health centres in the autonomous community of Murcia (Spain)., Methods: Construction of a questionnaire from a bank of 873 items from a systematic review and a Delphi study. Review by PCC panel of experts (8). Cognitive pretest with 10 FP. Doctors from 62 health centres were invited to participate. With the responses we measured reliability, validity and feasibility., Results: The final questionnaire contains 37 items. We measured reliability through internal consistency with a Cronbach's alpha of .915. For construct validity, the appropriate Bartlett's test of sphericity and the Kaiser-Mayer-Olkin measure of .889 allowed us to carry out a factor analysis with the extraction of nine factors (Kaiser's rule) with five main factors (Scree test) whose items coincide with the dimensions proposed by the experts. To assess its feasibility we considered the response rate of 31.15%, the response time of 17minutes 23seconds and only .9% of respondents considered the questionnaire long or complex., Conclusions: The ACPAPS questionnaire is a reliable, valid and feasible tool to assess PCC in FM, which has multiple and far-reaching applications., (Copyright © 2023 The Author(s). Publicado por Elsevier España, S.L.U. All rights reserved.)

Objectives: To know the perspective of professionals on aspects and dimensions that should be an indispensable part of Person-Centered Care (PCA)., Design: Delphi Technique., Location: Primary Care., Participants: 74 medical experts specializing in family and community medicine (FM), teaching tutors, psychologists and sociologists distributed throughout the national territory (January-June 2015)., Methods: They responded to three questionnaires: first, on aspects that a FP should take into account to carry out PCA in all its dimensions. In the second, they asked about the degree of agreement with each item and dimension in which it was classified. The responses were prioritized in a third questionnaire (Likert scale, score range 1-10)., Results: The response rate (RR) to the 1st questionnaire was 54.05%, obtaining 84 items, the most frequent Respect and Comprehensive Attention. The 2nd questionnaire with RR = 48.6%, obtained 52 items with a degree of agreement greater than 75%. The RR of the 3rd questionnaire was 52.7%, obtaining 21 items with a score> 9. The highest values corresponded to essential aspects of PCA: respect, comprehensive care, biopsychosocial approach, patient autonomy, and participation in decision-making., Conclusions: New dimensions were identified: Prevention and health promotion, Resource Management and Clinical Competence, added to those previously described: Biopsychosocial perspective, Doctor as a person, Patient as a person, Doctor-patient relationship and Shared Power and Responsibility. Respect, comprehensive care, the biopsychosocial approach, the patient's autonomy and their participation in decision-making, are the most valued aspects among those selected by the participating professionals., (Copyright © 2021 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.)

The objective of this study was to assess the impact of an education intervention for primary health care physicians, based on the knowledge of clinical practice guidelines and availability of rapid antigen detection test for group A streptococci (GAS), on the improvement of antibiotic prescription for patients with acute respiratory tract infections. Before and after the intervention, physicians collected data from ten consecutive patients who attended during a 3-week period. This process was performed twice a year for 6 consecutive years (2012-2017). A total of 18,001 patients were visited by 391 primary care physicians during the study period, 55.6% before intervention and 44.4% after intervention. After intervention, the antibiotic prescription decreased significantly, from 33.0 to 23.4% (p < 0.01). However, there was a statistically significant increase (p < 0.01) in the use of penicillins. This study, carried out in daily practice conditions, confirms that the educational strategy was associated with an overall reduction in the use of antibiotics and an improvement in the antibiotic prescription profile in acute respiratory tract infections.

Objective: Despite the acknowledged importance of 'Person Centered Care' (PCC), there are obvious limitations for its determination and measurement due to the difficulty of its exact definition. The objective of our review is to identify valid tools that measure the PCC or some of its aspects in the field of Primary Health Care., Design: Systematic review DATA SOURCES: MEDLINE, Embase, Cochrane, PSYCinfo, IME-Biomedicine, LILACS and TESEO until May 31, 2018., Selection of Studies: The inclusion criteria were: validation studies of questionnaires, systematic reviews of validation or other descriptive studies, all of which were carried out in the context of the Primary Health Care and that measured aspects of the PCC in professionals and/or patients. Two investigators independently reviewed the articles and their discrepancies were resolved by a third investigator., Data Extraction: Data were collected on the measured ACP aspects, target population, type of questionnaire, and data on validity and reliability., Results: 1,415 articles were located, to which 54 additional references were subsequently added via cross references. Finally, there were 75 articles that fulfilled all the criteria and there were 39 which had the tools identified and classified according to the dimensions analyzed., Conclusions: Due to the difficulty of measuring PCC as a whole, most of the articles refer only to one of its aspects or dimensions, with the patient's perspective prevailing over that of the professional. All these tools are, nevertheless, an important starting point for future questionnaires that attempt an integral approach to the PCC., (Copyright © 2020 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.)

Cardiovascular risk factors, specifically arterial hypertension, hyperlipidemia and diabetes, represent a very important part in relation to the emerging problem of overdiagnosis and overtreatment in primary health care. The reasons that support this threat are diverse. Given its high prevalence and the fact that the intervention on them is not going to be reflected directly in the state of health, it is added that the diagnostic criteria and indications for pharmacological treatment are not based on solid evidence. These recommendations have also been modified in recent years by virtue of professional consensus, with great potential for overtreatment and risk of undesirable effects on health. Therefore, it is essential to adequately evaluate the diagnostic criteria, inform of existing doubts and insist on the importance of changes in healthy habits such as diet and physical exercise, as well as actively reflect on the advantages and disadvantages of pharmacological treatment., (Copyright © 2018 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.)

Objective: To evaluate the impact of continuing education within the team (FCI, in Spanish) on the quality of minor surgery., Design: Study of level of quality. SETTING. Primary care., Participants: First evaluation: all the lesions referred for biopsy during 1998 (62 samples). Second evaluation: those referred in 1999-2000 (150)., Main Measurements: Four explicit criteria regulating procedure and result were designed: C1, sufficient information; C2, correct referral; C3, correct extirpation of lesion; C4, clinical-pathological concordance. Request forms and anatomical-pathological reports were assessed. Evaluation was before and after corrective measures (FCI and organisational changes designed to support FCI). The Kappa index of inter-observer concordance, the Compliance Index and Fisher's Z index were analysed., Results: 62 lesions were included in the first evaluation, with high reliability for C1 and C4, good for C2 and moderate for C3. 150 lesions were included in the second evaluation. The compliance indices showed statistically significant increases from the first to the second evaluation for C1 (38.09% and 50.66%, relative improvement of 19%) and C4 (68.85% and 85.2%, relative improvement of 53%). C2 showed an improvement, but without statistical significance (87.30% and 92.66%). The compliance index for C3 dropped (94.73% and 87.50%). 5.33% of cases in the second evaluation (8 biopsies) were malignant or pre-malignant lesions, compared with 20.96% in the first (P<.05). 100% of these latter showed free resection limits. 77.99% of lesions studied through a biopsy in the second evaluation were nevus, seborrhoeic keratosis or dermatofibroma., Conclusions: FCI is a valid strategy for improving the quality of programmes of minor surgery in primary care. There was significant improvement in the identification of malignant and pre-malignant pathology, in correct referral and in the clinical-pathological concordance of the lesions.

Objective: To evaluate improvement in therapeutic management of allergic rhinitis., Design: Study of level of quality (longitudinal, prospective, intervention)., Setting: Primary care., Patients and Others Participants: First evaluation (second quarter of 1995): 73 out of 305 patients were sampled (confidence 5%, accuracy 10%). Second evaluation (second quarter of 1996). Sample of 51 patients from a total of 210., Interventions: Explicit criteria and standard procedure, based on consensus, for rhinitis treatment and an overall indicator of the general quality of rhinitis management were analysed. Criterion 1 (C1): correctly scaled treatment; criterion 2 (C2): initial treatment of choice with inhaled corticoids; criterion 3 (C3): correct use of oral corticoids or immunotherapy; criterion 4 (C4): coadjutant therapy according to predominant symptoms. Corrective measures: ongoing training and routine use of guide to practice., Statistics: index of compliance with criteria, Chi squared and Fisher's Z tests of a tail to compare both evaluations., Measurements and Main Results: First evaluation: index of compliance with C1 = 59% (CI +/- 11), C2 = 41% (CI +/- 11), C3 = 90% (CI +/- 6) and C4 = 83% (CI +/- 8). Criteria and summary indicator obtained better results in patients attended by allergists. Second evaluation with overall improvement: C1 = 68.6% (CI +/- 13), C2 = 57% (CI +/- 13), C3 = 94% (CI +/- 6), C4 = 98% (CI +/- 3). Significant differences for C4 and C2 (p < 0.05). Overall quality and quality of criteria improved for patients attended in our environment. The summary indicator went up from 35.6% to 57% (p = 0.019), with the quality levels (C1-C4) becoming the same as those of the patients with allergy attended and with significant differences in the first evaluation disappearing., Conclusions: Ongoing training and routine use of guides to practice enables the therapeutic management of allergic rhinitis in primary care to be improved.

Objective: To describe the organisational atmosphere (OA) in primary care teams (PCTs) in an autonomous community., Design: Crossover and observational., Setting: PCTs., Participants: A questionnaire on OA was administered after prior validation to all the doctors, nurses and social workers at 29 PCTs., Measurements and Main Results: The OA in the different teams was described, comprehensively and by dimensions: team-work, cohesion and commitment. Multiple regression was used to find the relationship between OA (dependent variable) and the independent variables: age of the professionals, years of functioning of the PCT, teaching status, type, location (rural or urban) and profession (coordinators, doctors, nurses, clerical staff). Overall reply rate was 77.5% (402 professionals): it was higher for coordinators. Average score on the questionnaire was 3.53 (SD = 0.56): it was higher for nurses. Results by dimensions were: team-work 3.67 (SD = 0.59), cohesion 3.54 (SD = 0.71) and commitment 3.37 (SD = 0.72). OA was seen as better by teaching teams (p < 0.02), both overall and for the teamwork and cohesion dimensions. Coordinators had better self-perception of the OA, both overall and by dimensions (p < 0.01). Teams who had worked together for a long time thought the atmosphere was worse. The type of job and the number of years doing it did not affect the perception of OA., Conclusions: 1. The evaluation of OA is generally positive, though it can certainly be improved. 2. Perception is not uniform, as coordinators and teaching teams see the OA as better. 3. Teams working together for many years see the OA as worse.

Objective: To check the reliability and to analyse the validity of a questionnaire on organisational atmosphere (OA)., Design: Crossover and observational., Setting: Primary care teams (PCTs)., Participants: Two questionnaires were offered to all the doctors, nurses and social workers (548 professionals) from the 29 PCTs in an autonomous community. One questionnaire was on the OA and the other was a subjective assessment of satisfaction with the structure and functioning of their own team., Measurements and Main Results: When the results were analysed (initial factorial analysis), 3 items with only slight discrimination were eliminated from the OA questionnaire. Construction validity (factorial analysis with varimax method), reliability of the questionnaire (Cronbach's alpha and Spearman-Brown coefficient) and of criterion (correlation between OA and variables in the subjective assessment questionnaire) were calculated. The overall response rate was 77.5% (402 professionals). Three dimensions which explained 57% of total variability and which confirmed adequate construction validity were identified: team-work, cohesion and commitment. "Team-work" comprised 9 items and explained 27.18% of total variability. "Cohesion" had 7 items, which explained 16.55% of variability. Lastly, "Commitment" explained 13.47% of variability, with 5 items. The validity of criterion was adequate (close correlation between OA and subjective assessment of structure and operation). Reliability was high (0.89 alpha and 0.92 Spearman-Brown for the entire questionnaire and > 0.7 for the dimensions)., Conclusions: The reliability and validity of the adapted questionnaire are sufficient and permit its routine primary care use in our health system to be recommended.

Objective: To describe the style and effectiveness (adaptability) of the leadership of coordinators of an autonomous community according to the model of leadership on the ground, analysing its relationship with the work environment., Design: Observational crossover study., Setting: All the functioning teams in this community., Participants: Medical and nursing coordinators., Measurements and Main Results: Hersey and Blanchard's questionnaire on leadership on the ground was employed. This identifies 1) the predominant style (scoring for style 0-12). On the approach of the coordinator to personal relationships and/or task development, it identifies 4 points: direction, persuasion, participation, delegation. 2) Adaptability of the manager (ranging from +24 to -24), based on that the best choice between different options depends on the maturity of the group. To contrast work environment and leadership, a validated questionnaire, adapted to our milieu, was used. Overall reply rate (51 coordinators) was 89.4%. Analysis of styles was: persuasive 5.05 points (SD = 1.25), participatory 4.74 (SD 1.76), directive 1.2 (SD 1.11) and delegating 0.34 (SD 0.68). Adaptability scored 8.38 points (SD = 4.67), and was greater for the nursing coordinators (p < 0.002) without differences for type, place or teaching qualifications. The work environment, both overall and by dimensions, correlated with adaptability, although no relationship was found with leaders' styles., Conclusions: Leadership adaptability was quite high and greater in nursing. The most prevalent styles were the persuasive and the participatory, more efficacious in teams of average maturity. Theoretical effectiveness was positively related to a better work environment.

Objective: To describe nutritional habits in a Health District by defining the patterns of food consumption., Design: A descriptive, crossover study., Setting: Health District of Molina de Segura, Murcia., Method: A community survey by interview of 1,071 people (95% confidence; accuracy to 3%), selected from the Municipal Roll by simple randomised sampling, was performed. The statistical methods were: Chi-squared and Student's tests, ANOVA, Pearson's linear correlation, factorial and discriminatory analysis., Measurements and Main Results: 17.3%, especially men, never took milk products (p < 0.0005). 12.5%, mainly young people, consumed more than 3 eggs a week (p < 0.02). 85% ate fruit daily; 70%, green and root vegetables; and 78%, olive oil. 12.6% had pulses more than 3 days a week. Only 6.5% had potatoes or pasta daily. Among men and young people there was a "bar culture", along with a "fast food" pattern., Conclusions: The abandoned Mediterranean diet must be promoted. Measures should be taken to moderate young people's and men's alcohol consumption. "Fast food" and "bar culture" patterns are the most deeply rooted. The nutritional education of the chronically ill should also be emphasised.

Objective: To determine the differences in the diagnosis of light arterial hypertension between using three tension measurements (over 2 or 3 weeks) or five (6 or 7 weeks)., Design: A descriptive, longitudinal study., Setting: Santomera Health Centre, Murcia., Participants: In 245 patients initially diagnosed as suffering from light Hypertension (with three takes of blood pressure), two more tension measurements were taken, over four weeks, to make a definitive diagnosis of light arterial Hypertension. 156 patients completed the series, for whom the differences in diagnosis between three and five takes, and variations in their blood pressure figures on repetition of the measurements, were studied. There were no differences in patients' basic characteristics between those who completed the tests and those who didn't. But there were differences between different professionals regarding their compliance with the procedure., Results: 19.9% of the patients diagnosed initially after three blood pressure measurements did not have the diagnosis confirmed after five. Repetition of the measurements signified decrease in diastolic (p < 0.00005) and systolic (p < 0.00005) pressures. Average age of patients definitely diagnosed as having light hypertension was higher than the age of those not confirmed (p < 0.005). The older the patient, the higher the systolic pressure (p < 0.0001)., Conclusions: The diagnosis of light arterial hypertension differed in 19.9% between three measurements and five.

Objective: To describe a series of cases of carpal tunnel syndrome (CTS) diagnosed at our health centre, with an analysis of the influence of work activity., Design: A retrospective and descriptive study of a series of cases., Setting: Patients on two medical lists who sought health care., Participants: 27 people diagnosed as having CTS., Measurements and Main Results: We selected all the cases of CTS diagnosed according to the NIOSH criteria. We analysed symptoms, signs, additional tests and work risks. 24 out of the 27 cases were women. 100% had suggestive symptoms and 48.15% were affected bilaterally. The Tinell sign was positive in 5 cases, the Phalen in 7 and both in 11. 17.4% tested normal. We could see a diagnostic EMG in 19 cases. 59.2% were aged between 40 and 60. In all the cases we detected workplace risk factors: 18.5% housewives, 14.8% working in canning factories and dressmaking, 11.1% working in canning factories and dressmaking and shops/bars, 7.4% were cleaners, canning and fur operatives and mechanics. 3.7% worked at sewing shoes and in agriculture. As an accompanying pathology we detected 14.8% with obesity, 7.4% tenosynovitis and wrist fractures. For 3.7% CTS was a side-effect of diabetes, cervical arthrosis, ACV and dermatomyositis. 55.5% had non associated pathology., Conclusions: 1) The population of Molina de Segura can be considered at high risk of developing CTS. 2) In our environment women seek care for CTS much more often. 3) Most of our patients develop the condition in the workplace.

Objective: To find the prevalence of tobacco dependency in our community and to identify tobacco consumption in our chronic patients., Design: A crossover study. A descriptive analysis of the data., Setting: A Health District. Mixed population, both urban and rural., Participants: A Health Survey which included 1,071 individuals (95% Confidence and 3% precision), selected by means of simple random sampling from the Municipal Census., Measurements and Main Results: A 32.3% prevalence of tobacco dependency, greater among men (50.7%) than women (15.7%). Among the young, there is a marked tendency for the number of smokers to level out between the sexes. 15.6% of smokers consume more than 24 cigarettes per day. Between 15 and 20% of patients suffering hypertension, diabetes, hypercholesterolaemia and the effects of ischaemic cardiopathy, along with 25% of those who had suffered a CVA and almost 40% of chronic bronchitics, continue to smoke., Conclusions: Advice against smoking must be directed towards younger and younger age groups, including both men and women. The high prevalence of people still smoking among the chronically ill should cause us to reflect on our advice against tobacco to such patients.

Objective: Identification of the social profile of our anxious patients, and analysis of the usefulness of Bell's questionnaire for our area of work., Design: A retrospective observation study of a crossover type., Setting: Primary Care., Participants: 55 patients who consulted their Family Doctor and were diagnosed as suffering from Anxiety., Measurements and Main Results: We confirmed the diagnosis with the DSM-III-R and then analysed the level of Anxiety with the Hamilton Scale. The social evaluation was done by means of Bell's profile. As test statistics we used the lineal correlation Coefficient, the Student's t and Xi2 tests and Variance Analysis. 65% of diagnoses were Generalised Anxiety. The Hamilton mean was 20.9 points (S = 9.2). Overall social adaptation was unsatisfactory, with the worst results being for the emotional aspects. We observed a higher level of Anxiety as age increased (p = 0.021), related to a worse adaptation to Health (p = 0.014). Dissatisfaction with work and the working environment took the form of professional adaptation being poorer as their work situation deteriorated (p = 0.006). Anxiety levels were higher among the unemployed. Social adaptation was less among people with higher Anxiety levels (p = 0.04), above all as a consequence of worse adaptation to Health (p = 0.002) and worse emotional (p = 0.00001) adaptation., Conclusions: 1) We must introduce social aspects into analysis of patients with Anxiety. 2) Bell's profile enables us to identify those social aspects which can be tackled when caring for our patients. Its fundamental use is in individual application.

Objective: 1) To analyse the validity of the reply to the question on socio-economic income included in health questionnaires. 2) To identify other valid indicators of socio-economic status., Design: Crossover and retrospective observation study., Setting: Community (Molina de Segura Health District)., Participants: 1,071 people over 18, selected by means of simple random sampling., Interventions: Analysis of 16 questions relating to home furnishing, consumer goods and stated income. We used Factorial Analysis and the ji2 test., Results: We identified three levels by means of the factorial analysis: a) basic--consisting of hot water, washing-machine, absence of damp patches in the house, individual heating and television. b) Intermediate--consisting of car, video and telephone. c) High--with dishwasher, domestic help and air-conditioning. On analysing the relationship between stated income and socio-economic status we detected association to p < 0.001. The basic level answered more often than expected that their income was less than 50,000 pesetas; the intermediate, between 50 and 100,000; and the high, over 101,000., Conclusions: 1) It is possible to identify the socio-economic profile of the general population by the belonging of selected of determined consumer items. 2) Stated income is a reliable indicator of socio-economic status. Despite a tendency to a low reply to the question on income, income is not generally under-declared.

Background: To describe the Public Health in Primary Health Care practice for medical students Program objectives, quality of training evaluation method, and implementation results., Methods: 6 learning objectives were designed and training implemented in 3 Health Centers in the 90-91 academic course. Evaluation included the objectives level of difficulty, and homogeneity in achievement rates between objectives, within Centres and between Centres. Evaluation results were analyzed and used to design changes to increase homogeneity and achievement rates. Same evaluation was performed in the 91-92 academic course to document improvement., Results: In the first evaluation there were highly significant differences in overall (p. < 0.00005) and by objectives (p. > 0.01) achievement rates between centers. Within centres between objectives difficulty was not homogeneous either (p. > 0.001). After implementing remedial actions, differences in difficulty and achievement rates within and between centres decreased. Increased homogeneity affected mostly to two previously less homogeneous objectives., Conclusions: Quality assurance methods can be successfully applied to improve training of clearly defined and quantified Primary Health Care learning objectives.

Objective: Given both the limited experience of Undergraduate Teaching in Primary Health Care (PHC) and the lack of contact between different teaching centres, we sought to identify the minimum contents of a potential Syllabus. We made a distinction between items of knowledge required and skills students would have to develop., Design: We undertook a Delphi study, which was longitudinal, prospective and observational., Participants: We defined three groups of experts among groups with PHC teaching experience. 20 Associate Lecturers at Undergraduate level, attached to Health centres; 20 postgraduate PHC teachers, and 7 University staff members involved with Public Health and Preventive and Community Medicine teaching., Main Measurements and Results: The reply rate from the three questionnaires was about 60%. There was a high level of agreement. Of the items of knowledge which scored highest, we noted: the doctor-patients relationship, the Promotion of Health and Health education, Integrated Health Programmes, Prevention of Disease and Care of Risk-Groups. Of the skills, we pointed to the Clinical Interview, the construction of a Clinical History at the PHC level, Detection of Risk factors and Physical Examination., Conclusions: The most valued items of knowledge are those related to the overall Conception of Health, Promotion and Prevention. The most highly-scored skills are those concerning the Doctor-Patient relationship. Questions relating to the Individual are prioritised over those concerning Family and Community. There is a high level of agreement that the acquisition of the necessary theoretical knowledge must be accompanied by the ability to put them into practice.

The carpal tunnel syndrome is a neuropathy due to trapping (focal lesion of the peripheral nerve due to a local cause); in this case, the median nerve is the most commonly involved. Its presentation is characteristic in females about 40 years of age. The diagnosis is mainly based on clinical features and is confirmed by electrical criteria. In the anamnesis it is important to consider systemic diseases as causing the abnormality. Treatment depends on the etiology. It may be medical or surgical. In the present article we report three cases with different etiology and treatment. We also review the syndrome.