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1. Sustained seropositivity up to 20.5 months after COVID-19

Author

Dobaño, Carlota, Ramírez-Morros, Anna, Alonso, Selena, Rubio, Rocío, Ruiz-Olalla, Gemma, Vidal-Alaball, Josep, Macià, Dídac, Catalina, Queralt Miró, Vidal, Marta, Casanovas, Aina Fuster, Prados de la Torre, Esther, Barrios, Diana, Jiménez, Alfons, Zanoncello, Jasmina, Melero, Natalia Rodrigo, Carolis, Carlo, Izquierdo, Luis, Aguilar, Ruth, Moncunill, Gemma, and Ruiz-Comellas, Anna

Published
2022
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2. SARS-CoV-2 infection, vaccination, and antibody response trajectories in adults: a cohort study in Catalonia

Author

Karachaliou, Marianna, Moncunill, Gemma, Espinosa, Ana, Castaño-Vinyals, Gemma, Rubio, Rocío, Vidal, Marta, Jiménez, Alfons, Prados, Esther, Carreras, Anna, Cortés, Beatriz, Blay, Natàlia, Bañuls, Marc, Pleguezuelos, Vanessa, Melero, Natalia Rodrigo, Serra, Pau, Parras, Daniel, Izquierdo, Luis, Santamaría, Pere, Carolis, Carlo, Papantoniou, Kyriaki, Goldberg, Ximena, Aguilar, Ruth, Garcia-Aymerich, Judith, de Cid, Rafael, Kogevinas, Manolis, and Dobaño, Carlota

Published
2022
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3. Genome editing in animals with minimal PAM CRISPR-Cas9 enzymes

Author

Vicencio, Jeremy, Sánchez-Bolaños, Carlos, Moreno-Sánchez, Ismael, Brena, David, Vejnar, Charles E., Kukhtar, Dmytro, Ruiz-López, Miguel, Cots-Ponjoan, Mariona, Rubio, Alejandro, Melero, Natalia Rodrigo, Crespo-Cuadrado, Jesús, Carolis, Carlo, Pérez-Pulido, Antonio J., Giráldez, Antonio J., Kleinstiver, Benjamin P., Cerón, Julián, and Moreno-Mateos, Miguel A.

Published
2022
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4. Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses

Author

Ortega, Natalia, Ribes, Marta, Vidal, Marta, Rubio, Rocío, Aguilar, Ruth, Williams, Sarah, Barrios, Diana, Alonso, Selena, Hernández-Luis, Pablo, Mitchell, Robert A., Jairoce, Chenjerai, Cruz, Angeline, Jimenez, Alfons, Santano, Rebeca, Méndez, Susana, Lamoglia, Montserrat, Rosell, Neus, Llupià, Anna, Puyol, Laura, Chi, Jordi, Melero, Natalia Rodrigo, Parras, Daniel, Serra, Pau, Pradenas, Edwards, Trinité, Benjamin, Blanco, Julià, Mayor, Alfredo, Barroso, Sonia, Varela, Pilar, Vilella, Anna, Trilla, Antoni, Santamaria, Pere, Carolis, Carlo, Tortajada, Marta, Izquierdo, Luis, Angulo, Ana, Engel, Pablo, García-Basteiro, Alberto L., Moncunill, Gemma, and Dobaño, Carlota

Published
2021
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5. A Novel Monoclonal Antibody Targeting a Large Surface of the Receptor Binding Motif Shows Pan-neutralizing SARS-CoV-2 Activity Including BQ.1.1 Variant

Author

de Campos-Mata, Leire, primary, Trinité, Benjamin, additional, Modrego, Andrea, additional, Vaquero, Sonia Tejedor, additional, Pradenas, Edwards, additional, Melero, Natalia Rodrigo, additional, Carlero, Diego, additional, Marfil, Silvia, additional, Pons-Grífols, Anna, additional, Bueno-Carrasco, María Teresa, additional, Santiago, César, additional, Tarrés-Freixas, Ferran, additional, Urrea, Victor, additional, Izquierdo, Nuria, additional, Riveira-Muñoz, Eva, additional, Ballana, Ester, additional, Pérez, Mónica, additional, Vergara-Alert, Júlia, additional, Segalés, Joaquim, additional, Carolis, Carlo, additional, Arranz, Rocío, additional, Blanco, Julià, additional, and Magri, Giuliana, additional

Published
2023
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6. Maternal and neonatal immune response to SARS-CoV-2, IgG transplacental transfer and cytokine profile

Author

Rubio, Rocío, primary, Aguilar, Ruth, additional, Bustamante, Mariona, additional, Muñoz, Erica, additional, Vázquez-Santiago, Miquel, additional, Santano, Rebeca, additional, Vidal, Marta, additional, Melero, Natalia Rodrigo, additional, Parras, Daniel, additional, Serra, Pau, additional, Santamaria, Pere, additional, Carolis, Carlo, additional, Izquierdo, Luis, additional, Gómez-Roig, Maria Dolores, additional, Dobaño, Carlota, additional, Moncunill, Gemma, additional, and Mazarico, Edurne, additional

Published
2022
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7. SARS-CoV-2 infection, vaccination and antibody response trajectories in adults: a cohort study in Catalonia

Author

Karachaliou, Marianna, primary, Moncunill, Gemma, additional, Espinosa, Ana, additional, Castaño-Vinyals, Gemma, additional, Rubio, Rocío, additional, Vidal, Marta, additional, Jiménez, Alfons, additional, Prados, Esther, additional, Carreras, Anna, additional, Cortés, Beatriz, additional, Blay, Natàlia, additional, Bañuls, Marc, additional, Pleguezuelos, Vanessa, additional, Melero, Natalia Rodrigo, additional, Serra, Pau, additional, Parras, Daniel, additional, Izquierdo, Luis, additional, Santamaría, Pere, additional, Carolis, Carlo, additional, Papantoniou, Kyriaki, additional, Goldberg, Ximena, additional, Aguilar, Ruth, additional, Garcia-Aymerich, Judith, additional, de Cid, Rafael, additional, Kogevinas, Manolis, additional, and Dobaño, Carlota, additional

Published
2022
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8. Additional file 1 of Sustained seropositivity up to 20.5 months after COVID-19

Author

Dobaño, Carlota, Ramírez-Morros, Anna, Alonso, Selena, Rubio, Rocío, Ruiz-Olalla, Gemma, Vidal-Alaball, Josep, Macià, Dídac, Catalina, Queralt Miró, Vidal, Marta, Casanovas, Aina Fuster, Prados de la Torre, Esther, Barrios, Diana, Jiménez, Alfons, Zanoncello, Jasmina, Melero, Natalia Rodrigo, Carolis, Carlo, Izquierdo, Luis, Aguilar, Ruth, Moncunill, Gemma, and Ruiz-Comellas, Anna

Abstract

Additional file 1: Table S1. Association of baseline variables and comorbidities with levels of SARS-CoV-2 antibodies at time point 4 (January-February 2021) prior to the massive rollout of vaccination. Table S2. Seropositivity against the SARS-CoV-2 receptor-binding domain antigen from variants of concern. Table S3. Reinfections. Table S4. Significant associations of baseline variables with differential antibody rate of change. Fig. S1. Overall distribution of antibody responses for each isotype and antigen pair of the 128 pre-pandemic samples (negative controls) along with the cutoffs.

Published
2022
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9. Additional file 1 of SARS-CoV-2 infection, vaccination, and antibody response trajectories in adults: a cohort study in Catalonia

Author

Karachaliou, Marianna, Moncunill, Gemma, Espinosa, Ana, Castaño-Vinyals, Gemma, Rubio, Rocío, Vidal, Marta, Jiménez, Alfons, Prados, Esther, Carreras, Anna, Cortés, Beatriz, Blay, Natàlia, Bañuls, Marc, Pleguezuelos, Vanessa, Melero, Natalia Rodrigo, Serra, Pau, Parras, Daniel, Izquierdo, Luis, Santamaría, Pere, Carolis, Carlo, Papantoniou, Kyriaki, Goldberg, Ximena, Aguilar, Ruth, Garcia-Aymerich, Judith, de Cid, Rafael, Kogevinas, Manolis, and Dobaño, Carlota

Abstract

Additional file 1: Table S1. Characteristics of participants with breakthrough infections, post-vaccination. Table S2. Allocation of vaccinated and non-vaccinated participants with evidence of infection according to the criterion of infection fulfilled. Table S3. Fold change (FC) (95% CI) in antibody levels within one year after infection estimated using two repeated samples among decayers. Estimates are based on linear mixed-effects models. Table S4. Spearman correlations for RBD antigen. All participants, n=1,076. Darker red=stronger association. Table S5. Cross tabulation between serostatus to RBD of Wuhan variant with the RBD of Alpha, Beta Gamma and Delta variants. Table S6. Characteristics of non-responders (seronagetive or with an undetermined status) to vaccination. Table S7. Association (fold change FC and 95% CI and p-values) between each determinant with log10 antibody leves in vaccinated people after adjusting each model for time since last vaccination and number of doses. Participants with any vaccination excluding Janssen (n=923). Table S8. P-values for comparisons related to Figs. 3 and 5 and Figure S6. Figure S1. Dates and density of positive viral detection tests, sampling in 2020 (1st serological assessment) and 2021 (2nd serological assessment) and receipt of 1st vaccine dose in the study population (n=1,076). Figure S2. Venn diagram illustrating overlap between sustainer groups of IgA or IgG antibodies against nucleoprotein and spike antigens, among all infected unvaccinated participants (n=64). Figure S3. Differences in IgG antibody responses against RBD between Wuhan, Alpha, Beta, Gamma and Delta variant among vaccinated people. All differences were statistically significant apart from Delta vs Wuhan (p=0.861) and Alpha vs Wuhan (p=0.051). Figure S4. Generalized additive models for associations of days since vaccination with antibody responses to the six isotype-antigen combinations in infected (red) and naïve (blue) participants after first or second dose in people vaccinated by Vaxzevria (a), Comirnaty (b) or Spikevax (c). Fitted lines after adjustment for participant’s age. Plus symbols (+) represent measured responses for a specific participant. Figure S5. Differences in antibody responses by infection and/or vaccination and number of doses in people vaccinated with Comirnaty (a), Spikevarx (b), Vaxzevria (c) of Janssen COVID-19 vaccine (d). Figure S6. Differences in IgM responses by infection and/or vaccination and number of doses. Table S8 presents corresponding p-values.

Published
2022
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10. Genome editing in animals with minimal PAM CRISPR-Cas9 enzymes

Author

Vicencio, Jeremy, primary, Sánchez-Bolaños, Carlos, additional, Moreno-Sánchez, Ismael, additional, Brena, David, additional, Kukhtar, Dmytro, additional, Ruiz-López, Miguel, additional, Cots-Ponjoan, Mariona, additional, Vejnar, Charles E., additional, Rubio, Alejandro, additional, Melero, Natalia Rodrigo, additional, Carolis, Carlo, additional, Pérez-Pulido, Antonio J., additional, Giráldez, Antonio J., additional, Kleinstiver, Benjamin P., additional, Cerón, Julián, additional, and Moreno-Mateos, Miguel A., additional

Published
2021
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11. Persistence and baseline determinants of seropositivity and reinfection rates in health care workers up to 12.5 months after COVID-19

Author

Dobaño, Carlota, primary, Ramirez, Anna, additional, Alonso, Selena, additional, Vidal-Alaball, Josep, additional, Ruiz-Olalla, Gemma, additional, Vidal, Marta, additional, Rubio, Rocio, additional, Cascant, Emma, additional, Parras, Daniel, additional, Melero, Natalia Rodrigo, additional, Serra, Pau, additional, Carolis, Carlo, additional, Santamaria, Pere, additional, Forcada, Anna, additional, Mendioroz, Jacobo, additional, Aguilar, Ruth, additional, Moncunill, Gemma, additional, and Ruiz-Comellas, Anna, additional

Published
2021
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12. SARS-CoV-2 sculpts the immune system to induce sustained virus-specific naïve-like and memory B cell responses

Author

de Campos-Mata, Leire, primary, Vaquero, Sonia Tejedor, additional, Tachó-Piñot, Roser, additional, Piñero, Janet, additional, Grasset, Emilie K., additional, Aldea, Itziar Arrieta, additional, Melero, Natalia Rodrigo, additional, Carolis, Carlo, additional, Horcajada, Juan P., additional, Cerutti, Andrea, additional, Villar-García, Judit, additional, and Magri, Giuliana, additional

Published
2021
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13. Antibody Conversion rates to SARS-CoV-2 in Saliva from Children Attending Summer Schools in Barcelona, Spain

Author

Dobaño, Carlota, primary, Alonso, Selena, additional, Fernández de Sevilla, Mariona, additional, Vidal, Marta, additional, Jiménez, Alfons, additional, Tomas, Gemma Pons, additional, Jairoce, Chenjerai, additional, Melé Casas, María, additional, Rubio, Rocío, additional, Hernández García, María, additional, Ruiz-Olalla, Gemma, additional, Girona-Alarcón, Mònica, additional, Barrios, Diana, additional, Santano, Rebeca, additional, Mitchell, Robert A., additional, Puyol, Laura, additional, Mayer, Leonie, additional, Chi, Jordi, additional, Melero, Natalia Rodrigo, additional, Carolis, Carlo, additional, Garcia-Miquel, Aleix, additional, Bonet-Carne, Elisenda, additional, Claverol, Joana, additional, Cubells, Marta, additional, Fortuny, Claudia, additional, Fumadó, Victoria, additional, Jou, Cristina, additional, Muñoz-Almagro, Carmen, additional, Izquierdo, Luis, additional, Bassat, Quique, additional, Gratacós, Eduard, additional, Aguilar, Ruth, additional, García-García, Juan José, additional, Moncunill, Gemma, additional, and Jordan, Iolanda, additional

Published
2021
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14. Multiplex Antibody Analysis of IgM, IgA and IgG to SARS-CoV-2 in Saliva and Serum from Infected Children and their Close Contacts

Author

Dobaño, Carlota, primary, Alonso, Selena, additional, Vidal, Marta, additional, Jiménez, Alfons, additional, Rubio, Rocío, additional, Santano, Rebeca, additional, Barrios, Diana, additional, Tomas, Gemma Pons, additional, Melé Casas, María, additional, Hernández García, María, additional, Girona-Alarcón, Mònica, additional, Puyol, Laura, additional, Melero, Natalia Rodrigo, additional, Carolis, Carlo, additional, Garcia-Miquel, Aleix, additional, Bonet-Carne, Elisenda, additional, Claverol, Joana, additional, Cubells, Marta, additional, Fortuny, Claudia, additional, Fumadó, Victoria, additional, Codina, Anna, additional, Bassat, Quique, additional, Muñoz-Almagro, Carmen, additional, Fernández de Sevilla, Mariona, additional, Gratacós, Eduard, additional, Izquierdo, Luis, additional, García-García, Juan José, additional, Aguilar, Ruth, additional, Jordan, Iolanda, additional, and Moncunill, Gemma, additional

Published
2021
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15. Persistence and baseline determinants of seropositivity in health care workers up to nine months after COVID-19

Author

Dobaño, Carlota, primary, Ramirez, Anna, additional, Alonso, Selena, additional, Vidal-Alaball, Josep, additional, Ruiz-Olalla, Gemma, additional, Vidal, Marta, additional, Rubio, Rocio, additional, Cascant, Emma, additional, Parras, Daniel, additional, Melero, Natalia Rodrigo, additional, Serra, Pau, additional, Carolis, Carlo, additional, Santamaria, Pere, additional, Forcada, Anna, additional, Mendioroz, Jacobo, additional, Aguilar, Ruth, additional, Moncunill, Gemma, additional, and Ruiz-Comellas, Anna, additional

Published
2021
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16. Immunogenicity and crossreactivity of antibodies to SARS-CoV-2 nucleocapsid protein

Author

Dobaño, Carlota, primary, Santano, Rebeca, additional, Jiménez, Alfons, additional, Vidal, Marta, additional, Chi, Jordi, additional, Melero, Natalia Rodrigo, additional, Popovic, Matija, additional, López-Aladid, Rubén, additional, Fernández-Barat, Laia, additional, Tortajada, Marta, additional, Carmona-Torre, Francisco, additional, Reina, Gabriel, additional, Torres, Antoni, additional, Mayor, Alfredo, additional, Carolis, Carlo, additional, García-Basteiro, Alberto L., additional, Aguilar, Ruth, additional, Moncunill, Gemma, additional, and Izquierdo, Luis, additional

Published
2020
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17. SARS-CoV-2-Specific Antibody Profiles Distinguish Patients with Moderate from Severe COVID-19

Author

de Campos Mata, Leire, primary, Piñero, Janet, additional, Vaquero, Sonia Tejedor, additional, Tachó-Piñot, Roser, additional, Kuksin, Maria, additional, Aldea, Itziar Arrieta, additional, Melero, Natalia Rodrigo, additional, Carolis, Carlo, additional, Furlong, Laura, additional, Cerutti, Andrea, additional, Villar-García, Judit, additional, and Magri, Giuliana, additional

Published
2020
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18. Highly sensitive and specific multiplex antibody assays to quantify immunoglobulins M, A and G against SARS-CoV-2 antigens

Author

Dobaño, Carlota, primary, Vidal, Marta, additional, Santano, Rebeca, additional, Jiménez, Alfons, additional, Chi, Jordi, additional, Barrios, Diana, additional, Ruiz-Olalla, Gemma, additional, Melero, Natalia Rodrigo, additional, Carolis, Carlo, additional, Parras, Daniel, additional, Serra, Pau, additional, de Aguirre, Paula Martínez, additional, Carmona-Torre, Francisco, additional, Reina, Gabriel, additional, Santamaria, Pere, additional, Mayor, Alfredo, additional, García-Basteiro, Alberto, additional, Izquierdo, Luis, additional, Aguilar, Ruth, additional, and Moncunill, Gemma, additional

Published
2020
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