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22 results on '"Mele Dario Antonio"'

4. Preoperative Direct Puncture Embolization Using a Nonadhesive Ethylene Vinyl Alcohol (EVOH) Liquid Embolic Agent for Head and Neck Paragangliomas

Author

Alexandre, Andrea M., primary, Scarcia, Luca, additional, Clarençon, Frédéric, additional, Camilli, Arianna, additional, Bartolo, Andrea, additional, Incandela, Francesca, additional, Mele, Dario Antonio, additional, Rigante, Mario, additional, Natola, Marco, additional, Valente, Iacopo, additional, D’Argento, Francesco, additional, Galli, Jacopo, additional, Tshomba, Yamume, additional, and Pedicelli, Alessandro, additional

Published
2023
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7. Dupilumab in the treatment of severe uncontrolled chronic rhinosinusitis with nasal polyps): a multicentric observational phase IV real‐life study (DUPIREAL)

Author

De Corso Eugenio, Pasquini, Ernesto, Trimarchi, Matteo, La Mantia Ignazio, Pagella, Fabio, Ottaviano, Giancarlo, Garzaro, Massimiliano, Pipolo, Carlotta, Torretta, Sara, Seccia, Veronica, Cantone, Elena, Ciofalo, Andrea, Lucidi, Daniela, Fadda Gian Luca, Pafundi Pia Clara, Settimi, Stefano, Montuori, Claudio, Anastasi, Francesca, Pagliuca, Giulio, Ghidini, Angelo, Cavaliere, Carlo, Maffei, Marianna, Bussu, Francesco, Gallo, Stefania, Canevari Frank Rikki Mauritz, Paludetti, Gaetano, Galli, Jacopo, Spanu, Camilla, Porru Davide Paolo, Lo Verde Simone, Corbò, Marco, Cantiani, Alessandro, Furno, Daniela, D’Agostino, Giuseppe, D’Auria Leandro Maria, De Maio Gabriele, Di Bella Giuseppe Alberto, Penazzi, Daniele, Mele Dario Antonio, Di Cesare Tiziana, Andrea, Rampi, Umberto, Tanzini, Saccardo, Tommaso, Roccuzzo, Giuseppe, Cipolla, Federica, Ragusa, Martina, Grigaliute, Egle, Alicandri Ciufelli Matteo, Roncadi, Leonardo, Rizzo, Davide, De Vita Carla, Farneti, Paolo, Todero, Gabriella, Cristofani‐mencacci, Lodovica, Statuti, Erica, Cavallo, Giovanni, Urbanelli, Anastasia, Ferrella, Francesco, Arnone, Flavio, Di Nola Claudio, Pignataro, Lorenzo, Nava, Nicolò, Russo, Paolo, Savastano, Vincenzo, Masieri, Simonetta, Dell’Era, Valeria, Aluffi Valletti Paolo, Sovardi, Fabio, Siragusa, Vera, Clemenzi, Veronica, Stolfa, Andrea, Simoni, Edi, and Astolfi, Laura

Subjects
dupilumab, smell, biologics, dupireal, crswnp, asthma, biologics, chronic rhinosinusitis with nasal polyps, dupilumab, smell, asthma, chronic rhinosinusitis with nasal polyps
Published
2023

9. Bioradiotherapy with Cetuximab May Reduce the Risk of Neck Node Relapse in Locoregionally Advanced Laryngeal Glottic Carcinoma: May HER1-Profile Be Useful in the Bioselection of Patients?

Author

Almadori, Giovanni, primary, Coli, Antonella, additional, De Corso, Eugenio, additional, Settimi, Stefano, additional, Mele, Dario Antonio, additional, Brigato, Francesca, additional, Scannone, Domenico, additional, Galli, Jacopo, additional, Valentini, Vincenzo, additional, Paludetti, Gaetano, additional, Lauriola, Libero, additional, and Ranelletti, Franco Oreste, additional

Published
2022
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11. Additional file 1 of Parathyroid hormone-related peptide and parathyroid hormone-related peptide receptor type 1 in locally advanced laryngeal cancer as prognostic indicators of relapse and survival

Author

Almadori, Giovanni, Coli, Antonella, De Corso, Eugenio, Mele, Dario Antonio, Settimi, Stefano, Di Cintio, Giovanni, Brigato, Francesca, Scannone, Domenico, Lauriola, Libero, and Ranelletti, Franco Oreste

Abstract

Additional file 1: Supplementary Table 1.

Published
2022
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16. Efficacy and long-term follow-up of positional therapy by vibrotactile neck-based device in the management of positional OSA

Author

De Corso, Eugenio, primary, Mastrapasqua, Rodolfo F., additional, Fiorita, Antonella, additional, Settimi, Stefano, additional, Mele, Dario Antonio, additional, Picciotti, Pasqualina Maria, additional, Loperfido, Antonella, additional, Marrone, Sabino, additional, Rizzotto, Grazia, additional, Paludetti, Gaetano, additional, and Scarano, Emanuele, additional

Published
2020
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17. The usefulness of the IMAP propeller flap for trachea and tracheostome reconstruction after resection of parastomal recurrence of squamous cell carcinoma following salvage total laryngectomy

Author

Almadori, Giovanni, primary, Di Cintio, Giovanni, additional, De Corso, Eugenio, additional, Mele, Dario Antonio, additional, Settimi, Stefano, additional, Almadori, Aurora, additional, Cina, Alessandro, additional, Visconti, Giuseppe, additional, Paludetti, Gaetano, additional, and Salgarello, Marzia, additional

Published
2020
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18. Predictors of Disease Control After Endoscopic Sinus Surgery Plus Long-Term Local Corticosteroids in CRSwNP

Author

De Corso, Eugenio, primary, Settimi, Stefano, additional, Tricarico, Laura, additional, Mele, Dario Antonio, additional, Mastrapasqua, Rodolfo Francesco, additional, Di Cesare, Tiziana, additional, Salvati, Antonio, additional, Trozzi, Lucrezia, additional, De Vita, Carla, additional, Romanello, Matteo, additional, Paludetti, Gaetano, additional, and Galli, Jacopo, additional

Published
2020
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20. Antileukotrienes improve naso-ocular symptoms and biomarkers in patients with NARES and asthma

Author

De Corso, Eugenio, Anzivino, R, Galli, Jacopo, Baroni, Silvia, Di Nardo, Walter, De Vita, C, Salvati, Alessandra, Autilio, C, Settimi, Stefano, Mele, Dario Antonio, Paludetti, Gaetano, and Mullol, J

Subjects
Adult, Cyclopropanes, Male, antileukotrienes, Eye Diseases, precision medicine, Syndrome, Acetates, Sulfides, Asthma, montelukast, Eosinophilia, Nose Diseases, Quinolines, Humans, Leukotriene Antagonists, Female, eosinophils, Settore MED/31 - OTORINOLARINGOIATRIA, Prospective Studies, eotaxin, Biomarkers, Rhinitis
Abstract

The aim of our study was to analyze the montelukast effectiveness in improving oculonasal symptoms, patient-reported outcomes (PROs), and eosinophilic biomarkers in patients with nonallergic rhinitis eosinophilic syndrome (NARES).We enrolled prospectively 80 symptomatic patients treated with 10 mg once a day of montelukast in monotherapy for 2 months. All patients were investigated before and after treatment. Nasal symptoms (nasal obstruction, rhinorrhoea, sneezing, nasal itching), ocular symptoms (redness/puffiness, watery eyes), and other PROs (olfactory dysfunction, difficulty going to sleep, nighttime awakenings, and nasal congestion on awakening) were scored by visual analogic scale. The following clinical scores were assessed: Total Nasal Symptom Score (T4NSS), Total Ocular Symptom Score (T2OSS), Total Symptom Score of Patient-Reported Outcomes (TSS-PROs), and a Composite Symptoms Score (CSS). Patients were classified as responders when a reduction of at least 50% of the CSS was observed. Before and after treatment, the eosinophilic biomarkers in nasal lavage were analyzed: nasal eosinophilia (number of eosinophils per high power field), eotaxin-1 and eotaxin-2.After treatment, significant reductions were observed for all the symptom scores. Forty-two of 78 patients were considered responders. A significant reduction of eosinophils in nasal mucosa and of levels of eotaxin-1 and eotaxin-2 in nasal lavage were observed after treatment in responder patients. Patients with asthma had an increased probability to be responders.NARES patients may benefit from treatment with montelukast. In particular, the presence of concomitant asthma may be predictive of a greater efficacy.2 Laryngoscope, 129:551-557, 2019.

Published
2018

21. Predictors of Disease Control After Endoscopic Sinus Surgery Plus Long-Term Local Corticosteroids in CRSwNP.

Author

De Corso, Eugenio, Settimi, Stefano, Tricarico, Laura, Mele, Dario Antonio, Mastrapasqua, Rodolfo Francesco, Di Cesare, Tiziana, Salvati, Antonio, Trozzi, Lucrezia, De Vita, Carla, Romanello, Matteo, Paludetti, Gaetano, and Galli, Jacopo

Subjects
NASAL polyps, ENDOSCOPIC surgery, PREVENTIVE medicine, CORTICOSTEROIDS, EOSINOPHILS
Abstract

Background: in the era of new biological agents it is important to identify patients who may benefit from conventional therapies such as endoscopic sinus surgery (ESS) plus long-term local corticosteroids from those with patterns of inflammation that are more difficult to control post-operatively and who may benefit from other therapies. Objective: determine if preoperative assessment of type and grade of inflammation and clinical factors can predict disease control with ESS plus long-term local corticosteroids in chronic rhinosinusitis with nasal polyps (CRSwNP). Methods: Eighty patients treated with ESS plus mometasone-furoate 200 μg BID for CRSwNP and followed for at least 1 year were enrolled (November 2017–December 2018) in this prospective observational study. Type and grade of inflammation were evaluated preoperatively by nasal cytology. Based on cellular pattern, patients were grouped as neutrophilic (n = 20), eosinophilic (n = 38), or mixed eosinophil-neutrophilic (n = 22). SNOT-22 and Lund-Kennedy Endoscopic Score were evaluated at baseline and at 3, 6, 9, and 12 months after surgery and used to define disease control. Results: The cumulative probability of remaining free of significant modification of endoscopic score (Lund-Kennedy Endoscopic Score >2) at 3, 6, 9, and 12 months was 0.84, 0.76, 0.71, and 0.68, respectively. At 12-month postoperative evaluation good disease control was observed in 54 of 80 patients (67.5%). Compared to those with good post-operative disease control, those with poor control had a significantly higher pre-operative mean count of eosinophils and neutrophils (p < 0.05). The preoperative inflammatory pattern was associated with relative risk of poor control: neutrophilia (RR: 3.10; CI:1.24–7.71), eosinophilia (RR:8.42; CI:2.72–15.12), and mixed eosinophilic and neutrophilic (RR:25.11; CI:19.41–30.01). We also confirmed that asthma, allergy, blood eosinophilia, and ASA triad could predict poor control. Conclusions: The type and load of inflammation evaluated preoperatively and selected clinical factors can predict poor control of CRSwNP treated with ESS and local corticosteroids. [ABSTRACT FROM AUTHOR]

Published
2021
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22. Subjective visual vertical/horizontal and video head impulse test in dyslexic children.

Author

Picciotti PM, Mele DA, Settimi S, Mari G, D'Alatri L, and Galli J

Subjects
Humans, Child, Female, Male, Adolescent, Reflex, Vestibulo-Ocular physiology, Dyslexia physiopathology, Head Impulse Test
Abstract

Different studies have tried to establish a relationship between dyslexia and the vestibular system function. Subjective Visual Vertical/Horizontal (SVV and SVH) and Video Head Impulse Test (VHIT) are useful for studying the vestibular system and can be easily performed in children. Our aim was to evaluate the vestibular function in dyslexic children by SVV/SVH and VHIT. We enrolled 18 dyslexic children (10M/8F; mean age 10.7 ± 2.3 years; range 7-14 years) and 18 age-matched children with typical development of learning abilities. All children performed VHIT, SVV and SVH. We found normal gain and symmetry of vestibulo-ocular-reflex both in dyslexic and typically developing children. Fifteen out of 18 dyslexic children (83.3%) showed a difference of at least one amongst SVV or SVH. The mean value of SVV was 2.3° and the mean value of SVH was 2.6°. Statistical analysis showed a significant difference between typically developing and dyslexic children for both SVV and SVH. We confirm a relationship between dyslexia and the alteration of SVV and SVH. Our results could be related to the pathogenetic hypothesis of a visual processing impairment related to a dysfunction of the magnocellular pathway or to a general deficit related to a multimodal cortical network., (© 2024 The Author(s). Dyslexia published by John Wiley & Sons Ltd.)

Published
2024
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