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Mulualem Silesh,1 Tesfanesh Lemma Demisse,1 Birhan Tsegaw Taye,1 Kelem Desta,1 Tebabere Moltot Kitaw,1 Abinet Dagnaw Mekuria,2 Tiwabwork Tekalign Tafesse,3 Belete Fenta4 1Department of Midwifery, College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Public Health, College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia; 3School of Nursing, College of Health Science, Wolaita Sodo University, Wolaita Sodo, Ethiopia; 4School of Midwifery, Faculty of Health Science, Jimma University, Jimma, EthiopiaCorrespondence: Mulualem Silesh Email sileshmulualem22@gmail.comBackground: Coronavirus disease-2019 (COVID-19) is a highly contagious and cause for the death of many people worldwide. Due to physiological immunosuppressive state and mechanical alteration, pregnant women are at a higher risk of severe illness and adverse maternal and fetal outcomes from COVID-19 than non-pregnant women. Compliance with the preventive measures is essential to control COVID-19 related consequences. Therefore, this study aimed to assess compliance with COVID-19 preventive measures among pregnant women attending antenatal care at public facilities of Debre Berhan town, Ethiopia.Methods: A facility-based cross-sectional study was conducted from May 1 to 30, 2021 among 402 pregnant mothers. Data were collected via a face-to-face interviewer-administered questionnaire. Then, entered into Epi-Data version 4.6 and exported to SPSS version 25 for data analysis. In multivariable logistic regression analysis, variables with p < 0.05 were declared as statistically significant and the strength of statistical association was measured by adjusted odds ratio (AOR) and 95% confidence interval (CI).Results: Of the total 396 participants, 222 (56.1%) of women had a good compliance with COVID-19 preventive measures. Maternal age (25– 34 years) [AOR: 1.926; 95% CI (1.084, 3.421)] and (≥ 35 years) [AOR: 3.018; 95% CI (1.53, 5.952)], husband educational

Abrham Shitaw Tewachew,1 Wassie Negash Mekonnen,2 Abinet Dagnaw Mekuria,2 Yosef Eshetie Amare3 1Department of Medicine, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Public Health, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, Ethiopia; 3Department of Biomedical Sciences, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, EthiopiaCorrespondence: Yosef Eshetie AmareDepartment of Biomedical Sciences, Institute of Medicine and Health Sciences, Debre Berhan University, Debre Berhan, EthiopiaTel +251910966364Email yophy2006@gmail.comIntroduction: Opportunistic infections are an illness that exists more frequently and is more severe in people with HIV. In HIV/AIDS patients, opportunistic infections still cause morbidity and mortality even after the era of highly active antiretroviral therapy (HAART) and most patients die as direct or indirect complications of opportunistic infections. This study was aimed to identify the determinants for the occurrence of opportunistic infections in HIV-positive patients having HAART follow-up in DBRH, Debre Berhan, Ethiopia.Methods: A total of 339 study subjects were involved under institution-based unmatched case–control study design and simple random sampling technique. A pre-tested structured questionnaire was used for data collection. Data were entered using Epidata version 3.1 and analyzed for descriptive and logistic regression models by SPSS version 21. A P-value of less than 0.05 was considered as statistically significant.Results: After adjusting potential confounders, drinking alcohol (AOR=3.12, 95% CI: 1.07– 9.06), BMI < 18.5 (AOR= 3.36, 95% CI: 1.49– 7.55), previous history of opportunistic infections (AOR= 2.96, 95% CI: 1.51– 5.8) were independent predictors of opportunistic infections in people living with HIV/AIDS on HAART.Conclusion: In this study, t

Demelash Geset Haile, 1 Nigussie Taddess Sharew, 2 Abinet Dagnaw Mekuria, 3 Ayele Mamo Abebe, 2 Yordanos Mezemir 1 1Debre Berhan Health Science College, Department of Nursing, Debre Berhan, Ethiopia; 2Debre Berhan University Health Science College, Department of Nursing, Debre Berhan, Ethiopia; 3Debre Berhan University Health Science Colleges, Department of Public Health, Debre Berhan, EthiopiaCorrespondence: Abinet Dagnaw Mekuria Tel +251 913416934Email abinetdagn@gmail.comIntroduction: Hypertension is a serious medical condition that significantly increases the risks of heart, brain, kidney, and other diseases. The prevalence is highest in Africa (27%) and lowest in America (18%). Hypertension is a major reason for premature death worldwide; this is why it will become a targeted non-communicable disease by 2025.Objective: To assess the prevalence of hypertension and associated factors among adults in Debre Berhan town, Amhara region, Ethiopia.Methods: A community-based cross-sectional study was conducted among 680 participants who were selected by a systematic sampling technique. Data were checked, cleaned, and entered into Epi-data then exported to SPSS-23 for analysis. Hosmer-Lemeshow test was used to check the model fitness. Binary logistic regression analysis was used to see the association between dependent and independent variables. All variables with p < 0.25 were taken into the multivariable model to minimize the possible confounders. The multi collinearity test was carried out to see the correlation between independent variables by using a variance inflation factor (VIF). The odds ratio along with 95% CI were estimated to measure the strength of association and to identify factors associated with hypertension using multivariable logistic regression. Descriptive statistics in the form of tables, figures, percent with measure of central tendency and dispersion with multivariable analysis were used to report the findings and to identify the f

Abinet Dagnaw Mekuria,1 Assefa Legesse Sisay,2 Kassa Ketsela Hailegiorgies,3 Ayele Mamo Abebe4 1Department of Public Health, College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia; 2Department of Epidemiology and Bio-Statistics, Jimma University, Jimma, Ethiopia; 3Department of Nursing, College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia; 4Pediatrics nursing Department, College of Health Science, Debre Berhan University, Debre Berhan, EthiopiaCorrespondence: Ayele Mamo AbebePediatrics nursing Department, Debre Berhan University, College of Health Science, PO Box 445, Debre Berhan, EthiopiaEmail ayelemamo12@gmail.comBackground: Prevention of mother-to-child transmission of HIV (PMTCT) is a frequently used word for programs and intervention methods to decrease the risk of mother-to-child transmission of HIV. The aim of this study was to identify determinants of the reduction of CD4 count through time and the maternal transmission of HIV to their child on the PMTCT program at health centers in North Shewa Zone, Ethiopia.Methods: The cohort study design was conducted by using secondary data collected from the cohort register of PMTCT starting from September 1, 2014 to November 30, 2017. In this study, a longitudinal study was conducted for two types of result; these were longitudinal response measurements of HIV infected women CD4 count and the time to maternal transmission of HIV taken from 203 patients.Results: The prevalence rate of HIV infection among exposed infants was 5.58%. Baseline CD4 count, visiting times, weight, and interaction between visiting time and baseline CD4 count had a statistically significant effect on the longitudinal biomarker. From the Weibull AFT model, ART start, partner test, clinical stage, educational status, place of delivery, and MUAC were statistically significant. Hence, as a measurement unit decreased in square root CD4 cell count by 1.18 elevates the risk of maternal transmission of HIV.Con