Search

Purpose: To compare refractive-error quality of life, and spherical aberration in pseudophakic eyes with an aspherical intraocular lens (AcrySof IQ) vs. a conventional spherical intraocular lens (AcrySof Single-Piece). Methods: 65 patients were randomized to implantation of either an aspherical IOL (Alcon AcrySof IQ) (30 eyes) or a spherical IOL (Alcon AcrySof Single-Piece (35 eyes). Three months postoperatively, complete ophthalmologic examinations including uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BCVA), and a wavefront analysis were performed. Patients completed the National Eye Institute Refractive Error Quality of life Instrument (NEI RQL) to evaluate vision-related quality of life. Results: The mean postoperative best-corrected visual acuity was 0.09±0.07 logMAR in the aspherical group and 0.12±0.08 in the spherical group, and the difference was not statistically significant. Spherical aberrations were significantly lower in the aspherical group (0.12±0.23 μm), than in the spherical group (0.33±0.20 μm) (P=0.001). Patients with aspherical AcrySof IQ IOLs implantation also experienced less difficulties driving at night (P=0.04), but the difference was not significant after Bonferroni correction. Conclusion: The NEI RQL instrument is sensitive enough to detect the visual benefit of cataract surgery. The aspherical AcrySof IQ IOL reduces both spherical aberration and total higher-order aberrations, compared with the performance achieved by the spherical AcrySof Single-Piece IOL. Although the difference between the two IOLs is not statistically significant, there is a tendency toward the association of objective optical performance of aspherical AcrySof IQ IOLs with a subjective improvement in patients’ night driving.

Purpose To compare vision-related quality of life and higher-order aberrations (HOAs) with an aspherical intraocular lens (IOL) (AcrySof IQ SN60WF) and a conventional spherical IOL (AcrySof SA60AT) (both Alcon) after phacoemulsification. Setting Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China. Methods Sixty-five patients were prospectively randomized to receive an Alcon AcrySof IQ SN60WF IOL (30 eyes) or an AcrySof SA60AT IOL (35 eyes). All patients had a complete ophthalmologic examination including uncorrected visual acuity, best spectacle-corrected visual acuity (BSCVA), and wavefront analysis preoperatively and 3 months postoperatively. Patients also completed the National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) to evaluate vision-related quality of life. Results The mean postoperative BSCVA (logMAR) was 0.09 ± 0.07 (SD) in the aspherical IOL group and 0.12 ± 0.08 in the spherical IOL group; the difference was not statistically significant. Spherical aberrations were statistically significantly lower in the aspherical IOL group (mean 0.12 ± 0.23 μm) than in the spherical IOL group (mean 0.33 ± 0.20 μm) ( P = .001). Both IOL types improved most aspects of patients' vision-related quality of life. The aspherical IOL group had clinically significant improvement on more NEI VFQ-25 subscales, although the difference between groups in vision-related quality of life was not statistically significant. Conclusion Eyes with the aspherical AcrySof IQ SN60WF IOL had reduced HOAs and spherical aberrations compared with eyes with the spherical AcrySof SA60AT IOL; however, there were no statistically significant differences in visual acuity or vision-related quality of life between groups.