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145 results on '"Mehta, Pranav"'

1. Cell spheroid viscoelasticity is deformation-dependent

Author

Boot, Ruben C., van der Net, Anouk, Gogou, Christos, Mehta, Pranav, Meijer, Dimphna H., Koenderink, Gijsje H., and Boukany, Pouyan E.

Subjects
Condensed Matter - Soft Condensed Matter, Quantitative Biology - Tissues and Organs
Abstract

Tissue surface tension influences cell sorting and tissue fusion. Earlier mechanical studies suggest that multicellular spheroids actively reinforce their surface tension with applied force. Here we study this open question through high-throughput microfluidic micropipette aspiration measurements on cell spheroids to identify the role of force duration and cell contractility. We find that larger spheroid deformations lead to faster cellular retraction once the pressure is released, regardless of the applied force and cellular contractility. These new insights demonstrate that spheroid viscoelasticity is deformation-dependent and challenge whether surface tension truly reinforces.

Published
2024

4. Drying Kinetics with Proposed Model Study for Grapes Drying in Solar Dryer—A Case Study

Author

Mehta, Pranav, Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Haddar, Mohamed, Editorial Board Member, Kwon, Young W., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Bhattacharyya, Suvanjan, editor, and Chattopadhyay, Himadri, editor

Published
2023
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10. Extracellular fluid viscosity enhances cell migration and cancer dissemination

Author

Bera, Kaustav, Kiepas, Alexander, Godet, Inês, Li, Yizeng, Mehta, Pranav, Ifemembi, Brent, Paul, Colin D., Sen, Anindya, Serra, Selma A., Stoletov, Konstantin, Tao, Jiaxiang, Shatkin, Gabriel, Lee, Se Jong, Zhang, Yuqi, Boen, Adrianna, Mistriotis, Panagiotis, Gilkes, Daniele M., Lewis, John D., Fan, Chen-Ming, Feinberg, Andrew P., Valverde, Miguel A., Sun, Sean X., and Konstantopoulos, Konstantinos

Published
2022
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17. MOBBO: A Multiobjective Brown Bear Optimization Algorithm for Solving Constrained Structural Optimization Problems.

Author

Mehta, Pranav, Kumar, Sumit, Tejani, Ghanshyam G., Mohammad khishe, and Majumder, Himadri

Subjects
OPTIMIZATION algorithms, BROWN bear, STRUCTURAL engineering, STRUCTURAL optimization, METAL oxide semiconductor field
Abstract

The multiobjective (MO) optimizers show great promise in solving constrained engineering structural problems. This paper introduces a MO version of the Brown Bear Optimization (BBO) algorithm, inspired by the foraging behavior of brown bears. The proposed Multiobjective Brown Bear Optimization (MOBBO) algorithm is applied to five structural optimization problems, including 10‐bar, 25‐bar, 60‐bar, 72‐bar, and 942‐bar trusses, aiming to minimize both mass and maximum nodal deflection simultaneously. Comparative evaluations against six benchmark algorithms demonstrate MOBBO's superior convergence, solution diversity, and effectiveness in addressing highly constrained problems. The hypervolume (HV) and inverted generational distance (IGD) metrics place MOBBO in first rank according to the Friedman test, with an average standard deviation of 0.0002. Moreover, the spacing‐to‐extent (STE) and generational distance (GD) metrics rank MOBBO second. The final Friedman rank test highlights MOBBO's overall dominance, achieving a first rank. Best Pareto plots, diversity graphs, and box plot analyses further suggest MOBBO's superior performance and convergence compared to existing algorithms. Therefore, the MOBBO algorithm can be effectively applied to various MO optimization tasks in industry, offering refined global optimization solutions and contributing valuable insights to the field of MO algorithms. [ABSTRACT FROM AUTHOR]

Published
2024
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