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6 results on '"Mehrnaz Rasolinejad"'

1. Blood Sugar Trends in Patients with Diabetic Foot Ulcers: A Comparative Study before and after Amputation Surgery

Author

Mohammadreza Salehi, Leila Seddigh, sahar shafagh, Behshad Pazooki, Minoo Sadat Hajmiri, Banafsheh Moradmand-Badie, Nasim Khajavi Rad, Seyed Ali Dehghan Manshadi, Nima Bagheri, Mehrnaz Rasolinejad, and Seyed Mahmoud Sajadi Jazi

Subjects
Diabetic Foot, Amputation, Ulcer, Blood Suger, Medicine
Abstract

Background: The diabetic foot is a chronic complication of diabetes. There is a strong relationship between glucose levels, the severity of diabetic foot ulcers (DFUs), and the need for amputation. This study aimed to evaluate the blood sugar (BS) trends before and after surgery in patients with DFU who had been amputated. Methods: The adult patients who had undergone DFU-related amputation surgery between 2017 and 2020 in Imam Khomeini Hospital Complex, Tehran, Iran, were evaluated. The cases whose BS levels were charted at least three days before and after amputation were recruited. The main data, including hypoglycemia (defined as a blood glucose level < 70 mg/dl) and mean BS and fasting BS (FBS) levels, were recorded. The data were then analyzed and compared before and after amputation. Results: Of 267 patients reviewed for inclusion criteria, 55 patients were included in the study. Twenty-eight patients (50.9%) were men, and the mean age was 60 years. The mean FBS before and after amputation was 229.5 and 181.3 mg/dl, respectively, and the mean BS before and after amputation was 227.3 and 197.8 mg/dl, respectively. The differences were significant (P < 0.001). Twelve patients (21.8%) before and 21 patients (36.4%) after amputation suffered from hypoglycemia (P = 0.057). Conclusion: DFU-related amputation is associated with a significant decrease in blood glucose levels and inflammatory indexes. However, it can increase the risk of hypoglycemia during the first three days after the surgery.

Published
2023
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2. Lack of HIV infection among truck drivers in Iran using rapid HIV test

Author

Hossain Jabbari, Seyed Ahmad Seyed Alinaghi, Parastoo Kheirandish, Gholam Reza Esmaeli Djavid, Mehrnaz Rasolinejad, Mahboube Hajiabdolbaghi, Abbas Sedaghat, Maryam Sargolzaei, Amir Houshang Sharifi, Minoo Mohraz, and Kaveh Khoshnoud

Subjects
Human Immunodeficiency Virus, Truck, Automobile Driving, Medicine
Abstract

Background: The aim of this study was to evaluate the prevalence of HIV infection in Iranian long distance truck drivers using rapid HIV test. Methods: The study included 400 consecutive participants in Bazargan city, north-west of Iran in the late 2008 and the early 2009. Results: No HIV infection was observed among these long distance truck drivers. Conclusions: Although results of this study is plausible compared to other similar studies, repeated surveys are necessary to know the trend of HIV infection in truckers in Iran.

Published
2010

3. Evaluation of Serum Procalcitonin in Patients with Systemic Inflammatory Response Syndrome with and without Infection

Author

Zahra Ahmadinejad, Banafshe Dadsetan, Mohammad Jalili, Abdolreza Soudbakhsh, and Mehrnaz Rasolinejad

Subjects
Systemic inflammatory response syndrome, sepsis, procalcitonin, emergency department, Medicine (General), R5-920
Abstract

Procalcitonin (PCT) is a precursor peptide for the hormone calcitonin and is frequently increased in overt sepsis. The aim of this study was to test diagnostic accuracy of procalcitonin among patients with positive systemic inflammatory response syndrome (SIRS) in identifying sepsis. In this cross sectional study, from 563 patients with positive SIRS admitted through the emergency department of a university hospital, we included 120 patients. Procalcitonin was measured semi-quantitatively. Two groups of patients (with and without infection) were defined based on clinical, laboratory and bacteriologic findings throughout the admission course; the serum PCT levels were compared between the two groups. Seventy two (60%) patients were male and 48 (40%) were female, and the mean age was 49.1 ± 20.2years. Final diagnosis was infection in 71 patients (59.2%) and 49 (40.8%) had non-infectious SIRS. When considering PCT > 0.5 μg/L as the cut-off point, PCT had a sensitivity of 88.7%, a specificity of 77.6%, a positive predictive value of 85.1% and a negative predictive value of 82.6%. Serum level of procalcitoninin infectious group was significantly higher than in non-infectious group (P < 0.0001). PCT level was a predictor of mortality in patients with infectious SIRS. (P = 0.01) In summary, PCT is a useful marker for differentiating sepsis from other cause of SIRS. With change in the cut-off value of PCT in any situation its application can be maximized. Procalcitonin can also be a good marker for predicting outcome in patients with infection.

Published
2009

4. Efficacy and Safety of Arbidol in Treatment of Patients with COVID-19 Infection: A Randomized Clinical Trial

Author

Sara Ghaderkhani, Arezoo Salami Khaneshan, Amir Salami, Parvaneh Ebrahimi Alavijeh, Hamid Emadi Kouchak, Hossein Khalili, Ali Asadollahi-Amin, SeyedAhmad SeyedAlinaghi, Zahra Ahmadinejad, Mehrnaz Rasolinejad, Mahboubeh Hajiabdolbaghi, Sirous Jafari, Malihe Hasannezhad, Arash Seifi, Ladan Abasian, and Fereshte Ghiasvand

Subjects
General Medicine
Abstract

Background: COVID-19 has led to the demand for finding effective antiviral agents. Preliminary experiments showed Umifenovir inhibit replication in vivo. There is limited data on the clinical efficacy of COVID-19-infected pneumonia. Therefore, we aimed to evaluate this medication based on clinical findings. Methods: The present study was designed to investigate the advantages and disadvantages of Umifenovir and compared to empirical treatments. For this purpose, multi-stage sampling was considered. 56 people who had mild-to-moderate symptoms without signs of pneumonia, were selected by accidental non-random sampling method and divided into two groups [(group A with Hydroxychloroquine (HCQ) and group B in combination with Umifenovir] by randomized block sampling (1:1). During the study, three patients left the case group. Their clinical signs and symptoms were evaluated on 3rd, 7th, and 14th day after taking these medicines in the disease course. The SPSS software was used for data analysis and the significance level was considered to be p

Published
2022

5. Efficacy and Safety of Arbidol in Treatment of Patients with COVID-19 Infection: A Randomized Clinical Trial

Author

Arezoo salami khaneshan, Ladan abasian, Sirous Jafari, Hamid Emadi Kouchak, Mehrnaz Rasolinejad, Arash Seifi, Foroogh Alborzi Avanaki, Maryam Edalatifard, SeyedAhmad SeyedAlinaghi, Fereshte Ghiasvand, Zahra Ahmadinejad, Mojgan Rahimi, Amir Salami, Sara Ghaderkhani, Hossein Khalili, Malihe Hasannezhad, Parvaneh ebrahimi alavijeh, and Mahboubeh Hajiabdolbaghi

Subjects
medicine.medical_specialty, Text mining, Coronavirus disease 2019 (COVID-19), Randomized controlled trial, business.industry, law, Internal medicine, medicine, business, law.invention
Abstract

Background: The outbreak of COVID-19has led to a high demand for finding effective antiviral agents. Preliminary experiments showed that Umifenovir could inhibit coronavirus replication in vivo. There is limited data on the clinical efficacy of COVID-19-infected pneumonia. Therefore, we aimed to evaluate this medication based on clinical findings.Methods: The present study was designed as a clinical trial to investigate the advantages and disadvantages of this medicine compared to empirical treatment. For this purpose, multi-stage sampling was considered. 56 people who have mild to moderate symptoms without signs of sever pneumonia , were selected by accidental non-random sampling method. This sample size was subsequently divided into two groups (group A threated with hydroxycloroquine and group B who threated with combination hydroxycloroquine and Umifenovir) by randomized block sampling (1:1). During the study, three patients left the case group. Their clinical sighns and symptoms were evaluated on 3 th and 7 th and 14 th days after oncet illness while taking these medicines in the disease course. The SPSS software was used for data analysis and the significance level was considered to be PResults: On the seventh days after visit patients , there were statistically significant differences in recuperation dry cough(p = 0.001), weakness(p = 0.004), gastrointestinal symptoms(p = 0.043) and shortness of breath (p = 0.001) between the two groups, so that in patients who under orescription combination HCQ and Umifenovir group had a faster recovery.Generally during illness , there were statistically significantly faster melioratation myalgia(p = 0.03), gastrointestinal symptoms(p = 0.047), and weakness(p = 0.007)in patients who threated with both HCQ and Umifenovir .Conclusion: Evaluation clinical findings in mild to moderate COVID-19 patients symptoms and sighns recuperation faster in group who under orescription combination HCQ and Umifenovir .regimen. In other words, adding Umifenovir to the empirical treatment accelerated the recovery process of patients’ clinical symptoms.Registration: IR.TUMS.VCR.REC.1399.204, 04.13.2020 , http://ethics.research.ac.ir/IR.TUMS.VCR.REC.1399.204

Published
2021

6. Multi Lobulated Soft Tissue Tuberculosis Abscess in the Forearm of a Rheumatoid Arthritis Patient: A Case Report

Author

Mohammad Salehi, Afsaneh Pargar, and Mehrnaz Rasolinejad

Subjects
medicine.medical_specialty, Tuberculosis, biology, business.industry, Public Health, Environmental and Occupational Health, Soft tissue, bacterial infections and mycoses, Toxicology, Critical Care and Intensive Care Medicine, medicine.disease, biology.organism_classification, Cold abscess, Surgery, Mycobacterium tuberculosis, Chronic infection, Infectious Diseases, Rheumatoid arthritis, medicine, Body region, Abscess, business
Abstract

Introduction: Tuberculosis is a chronic bacterial infection that is caused by Mycobacterium tuberculosis. This chronic infection is amongst important of reasons for morbidity and mortality in the world. Cutaneous tuberculosis is a rare form of extra pulmonary involvement. Case Presentation: The case was a 42-year-old female, a known case of rheumatoid arthritis that was receiving prednisolone, and presented multi-lobulated soft tissue abscess in the forearm. Smear of the drained pus had 3+ Acid Fast Bacilli (AFB) and culture of the drained material confirmed Mycobacterium tuberculosis. Conclusions: The detection of Mycobacterium tuberculosis is always an important differential diagnosis for skin and soft tissue involvement in endemic areas. The cold abscess is an uncommon form of cutaneous tuberculosis that can be single or multiple and with or without fistula.

Published
2015

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