Search

Your search keyword '"Mehregan, David A."' showing total 173 results
Start Over Author "Mehregan, David A."
173 results on '"Mehregan, David A."'

18. Familial anetoderma

Author

Thomas, Jean E., Mehregan, Darius R., Holland, Jean, and Mehregan, David A.

Published
2003

28. Malignant melanoma in childhood

Author

Mehregan, Amir H. and Mehregan, David A.

Subjects
Melanoma -- Diagnosis, Cancer in children -- Case studies, Health
Abstract

Six cases of malignant melanoma in children 14 years of age and younger are reported. The six cases were diagnosed among 850,000 consecutive skin biopsy specimens and consultation slides examined within a 32-year period. This series included an infant born with neurocutaneous melanosis, a child with malignant melanoma developing in a large congenital nevus at the age of 13 years, a superficial spreading malignant melanoma, Clark Level III, in a child with many dysplastic nevi, and three cases with primary nodular malignant melanoma, two of which showed histologic features of Spitz nevus. A review of the literature indicates that malignant melanoma in childhood is rare, and no large series have been investigated. It is not known whether the genetic and the environmental factors incriminated in the development of malignant melanoma in adults play a role in childhood melanomas. Data on the incidence of childhood melanoma in the population, the clinical and the histologic variations, and the prognosis are not adequate. A multiinstitutional study is needed to gather a large enough series to provide this information.

Published
1993

29. Cutaneous botryomycosis

Author

Mehregan, David A., Su, W.P. Daniel, and Anhalt, John P.

Subjects
Cutaneous manifestations of general diseases -- Case studies, Antibiotics -- Evaluation, Bacterial infections -- Causes of, Health
Abstract

Botryomycosis is a rare and chronic infectious disease characterized by the formation of grape-like clusters of granules. Although it is frequently mistaken for a fungal infection, botryomycosis may be caused by various types of bacteria, including Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and others. The disease commonly affects the skin, most often on the limbs, although lesions may also develop in the skin of the trunk, face, and anal area. Botryomycosis may also involve the abdominal organs, mouth, tongue, brain, and eye. Cases are described of four patients with botryomycosis affecting the skin. Risk factors for botryomycosis include alcoholism, diabetes, and trauma, or injury. The patients cited here developed node-like growths, pus-producing patches, or ulcers. The types of bacteria isolated from the patients included Staphylococcus aureus in two cases, Neisseria species in one case, and coagulase-negative Staphylococcus and Corynebacterium species in one case. All patients were successfully treated with antibiotics. (Consumer Summary produced by Reliance Medical Information, Inc.)

Published
1991

33. Ustekinumab: differential use in psoriasis

Author

Uhlenhake, Elizabeth and Mehregan,David

Subjects
Clinical, Cosmetic and Investigational Dermatology
Abstract

Elizabeth E Uhlenhake, David A MehreganWayne State University Department of Dermatology, Wayne State University School of Medicine, Detroit, MI, USAAbstract: Chronic plaque psoriasis is a systemic disease affecting over 3% of the population, and many patients are unsatisfied with their current treatment regimen. With advances in understanding of the pathophysiology of psoriasis, new therapeutic options are being developed. The newest of these agents, ustekinumab, offers patients rapid results and the convenience of four annual subcutaneous doses, with efficacy and safety profiles comparable with those of other biologics. However, ustekinumab has been on the market in the US for less than 2 years and will require years of extensive use before the full adverse event profile is fully understood. The purpose of this paper is to summarize the treatment options currently available for psoriasis, with an emphasis on ustekinumab in order to give prescribers an overview of the available data and allow them to make educated and informed prescribing decisions.Keywords: psoriasis, treatment, ustekinumab, safety, biologicsA Letter to the Editor has been received and published for this article.

Published
2011

36. Ustekinumab: differential use in psoriasis

Author

Uhlenhake,Elizabeth E, Mehregan,David A, Uhlenhake,Elizabeth E, and Mehregan,David A

Abstract

Elizabeth E Uhlenhake, David A MehreganWayne State University Department of Dermatology, Wayne State University School of Medicine, Detroit, MI, USAAbstract: Chronic plaque psoriasis is a systemic disease affecting over 3% of the population, and many patients are unsatisfied with their current treatment regimen. With advances in understanding of the pathophysiology of psoriasis, new therapeutic options are being developed. The newest of these agents, ustekinumab, offers patients rapid results and the convenience of four annual subcutaneous doses, with efficacy and safety profiles comparable with those of other biologics. However, ustekinumab has been on the market in the US for less than 2 years and will require years of extensive use before the full adverse event profile is fully understood. The purpose of this paper is to summarize the treatment options currently available for psoriasis, with an emphasis on ustekinumab in order to give prescribers an overview of the available data and allow them to make educated and informed prescribing decisions.Keywords: psoriasis, treatment, ustekinumab, safety, biologicsA Letter to the Editor has been received and published for this article.

Published
2011

41. Pulsed dye laser therapy for sun damaged skin

Author

Zelickson, Brian D., primary, Kilmer, Suzanne L., additional, Bernstein, Eric, additional, Chotzen, Vera A., additional, Dock, Jayson, additional, Mehregan, David, additional, and Coles, Charlotte, additional

Published
1999
Full Text
View/download PDF

48. Spindle Cell Lipomas

Author

MEHREGAN, DARIUS R., primary, MEHREGAN, DAVID A., additional, DORMAN, MICHAEL A., additional, MEHREGAN, AMIR H., additional, and COHEN, EDWIN, additional

Published
1995
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results