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1,763 results on '"Mehrabi, Arianeb"'

2. Comparing a virtual reality head-mounted display to on-screen three-dimensional visualization and two-dimensional computed tomography data for training in decision making in hepatic surgery: a randomized controlled study

Author

Preukschas, Anas Amin, Wise, Philipp Anthony, Bettscheider, Lisa, Pfeiffer, Micha, Wagner, Martin, Huber, Matthias, Golriz, Mohammad, Fischer, Lars, Mehrabi, Arianeb, Rössler, Fabian, Speidel, Stefanie, Hackert, Thilo, Müller-Stich, Beat Peter, Nickel, Felix, and Kenngott, Hannes Götz

Published
2024
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6. Low‐dose aspirin confers protection against acute cellular allograft rejection after primary liver transplantation

Author

Oberkofler, Christian E, Raptis, Dimitri A, Müller, Philip C, da Silva, Richard X Sousa, Lehmann, Kuno, Ito, Takahiro, Owen, Timothy, Pollok, Joerg‐Matthias, Parente, Alessandro, Schlegel, Andrea, Peralta, Peregrina, Winter, Erin, Selzner, Markus, Fodor, Margot, Maglione, Manuel, Jaklitsch, Manuel, Marques, Hugo P, Chavez‐Villa, Mariana, Contreras, Alan, Kron, Philipp, Lodge, Peter, Alford, Scott, Rana, Abbas, Magistri, Paolo, Di Benedetto, Fabrizio, Johnson, Bethany, Kirchner, Varvara, Bauldrick, Francis, Halazun, Karim J, Ghamarnedjad, Omid, Mehrabi, Arianeb, Basto, Samanta Teixeira, Fernandes, Eduardo SM, Paladini, Jose, de Santibañes, Martin, Florman, Sander, Tabrizian, Parissa, Dutkowski, Philipp, Clavien, Pierre‐Alain, Busuttil, Ronald W, Kaldas, Fady M, and Petrowsky, Henrik

Subjects
Digestive Diseases, Liver Disease, Clinical Research, Transplantation, Organ Transplantation, Prevention, Adult, Humans, Liver Transplantation, Cohort Studies, Graft Rejection, Thrombosis, Allografts, Graft Survival, Retrospective Studies, Risk Factors, Clinical Sciences, Surgery
Abstract

This study investigated the effect of low-dose aspirin in primary adult liver transplantation (LT) on acute cellular rejection (ACR) as well as arterial patency rates. The use of low-dose aspirin after LT is practiced by many transplant centers to minimize the risk of hepatic artery thrombosis (HAT), although solid recommendations do not exist. However, aspirin also possesses potent anti-inflammatory properties and might mitigate inflammatory processes after LT, such as rejection. Therefore, we hypothesized that the use of aspirin after LT has a protective effect against ACR. This is an international, multicenter cohort study of primary adult deceased donor LT. The study included 17 high-volume LT centers and covered the 3-year period from 2013 to 2015 to allow a minimum 5-year follow-up. In this cohort of 2365 patients, prophylactic antiplatelet therapy with low-dose aspirin was administered in 1436 recipients (61%). The 1-year rejection-free survival rate was 89% in the aspirin group versus 82% in the no-aspirin group (hazard ratio [HR], 0.77; 95% confidence interval [CI], 0.63-0.94; p = 0.01). The 1-year primary arterial patency rates were 99% in the aspirin group and 96% in the no-aspirin group with an HR of 0.23 (95% CI, 0.13-0.40; p

Published
2022

7. Metavert synergises with standard cytotoxics in human PDAC organoids and is associated with transcriptomic signatures of therapeutic response

Author

An, Jingyu, Kurilov, Roma, Peccerella, Teresa, Bergmann, Frank, Edderkaoui, Mouad, Lim, Adrian, Zhou, Xu, Pfütze, Katrin, Schulz, Angela, Wolf, Stephan, Hu, Kai, Springfeld, Christoph, Mughal, Sadaf S., Zezlina, Lenart, Fortunato, Franco, Beyer, Georg, Mayerle, Julia, Roth, Susanne, Hulkkonen, Johannes, Merz, Daniela, Ei, Shigenori, Mehrabi, Arianeb, Loos, Martin, Al-Saeedi, Mohammed, Michalski, Christoph W., Büchler, Markus W., Hackert, Thilo, Brors, Benedikt, Pandol, Stephen J., Bailey, Peter, and Neoptolemos, John P.

Published
2024
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10. Carbon ion radiotherapy of hepatocellular carcinoma provides excellent local control: The prospective phase I PROMETHEUS trial

Author

Hoegen-Saßmannshausen, Philipp, Naumann, Patrick, Hoffmeister-Wittmann, Paula, Ben Harrabi, Semi, Seidensaal, Katharina, Weykamp, Fabian, Mielke, Thomas, Ellerbrock, Malte, Habermehl, Daniel, Springfeld, Christoph, Dill, Michael T., Longerich, Thomas, Schirmacher, Peter, Mehrabi, Arianeb, Chang, De-Hua, Hörner-Rieber, Juliane, Jäkel, Oliver, Haberer, Thomas, Combs, Stephanie E., Debus, Jürgen, Herfarth, Klaus, and Liermann, Jakob

Published
2024
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13. Short-term postoperative outcomes of lymphadenectomy for cholangiocarcinoma, hepatocellular carcinoma and colorectal liver metastases in the modern era of liver surgery: Insights from the StuDoQ|Liver registry

Author

Knitter, Sebastian, Raschzok, Nathanael, Hillebrandt, Karl-Herbert, Benzing, Christian, Moosburner, Simon, Nevermann, Nora, Haber, Philipp, Gül-Klein, Safak, Fehrenbach, Uli, Lurje, Georg, Schöning, Wenzel, Fangmann, Josef, Glanemann, Matthias, Kalff, Jörg C., Mehrabi, Arianeb, Michalski, Christoph, Reißfelder, Christoph, Schmeding, Maximilian, Schnitzbauer, Andreas A., Stavrou, Gregor A., Werner, Jens, Pratschke, Johann, and Krenzien, Felix

Published
2024
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17. Liver Histology Predicts Liver Regeneration and Outcome in ALPPS: Novel Findings From A Multicenter Study

Author

Lopez-Lopez, Victor, Linecker, Michael, Caballero-Llanes, Albert, Reese, Tim, Oldhafer, Karl J., Hernandez-Alejandro, Roberto, Tun-Abraham, Mauro, Li, Jun, Fard-Aghaie, Mohammad, Petrowsky, Henrik, Brusadin, Roberto, Lopez-Conesa, Asuncion, Ratti, Francesca, Aldrighetti, Luca, Ramouz, Ali, Mehrabi, Arianeb, Autran Machado, Marcel, Ardiles, Victoria, De Santibañes, Eduardo, Marichez, Arthur, Adam, René, Truant, Stéphanie, Pruvot, Francois-René, Olthof, Pim B., Van Gulick, Thomas M., Montalti, Roberto, Troisi, Roberto I., Kron, Philipp, Lodge, Peter, Kambakamba, Patryk, Hoti, Emir, Martinez-Caceres, Carlos, de la Peña-Moral, Jesus, Clavien, Pierre-Alain, and Robles-Campos, Ricardo

Published
2024
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19. Deep Learning–Enabled Diagnosis of Liver Adenocarcinoma

Author

Albrecht, Thomas, Rossberg, Annik, Albrecht, Jana Dorothea, Nicolay, Jan Peter, Straub, Beate Katharina, Gerber, Tiemo Sven, Albrecht, Michael, Brinkmann, Fritz, Charbel, Alphonse, Schwab, Constantin, Schreck, Johannes, Brobeil, Alexander, Flechtenmacher, Christa, von Winterfeld, Moritz, Köhler, Bruno Christian, Springfeld, Christoph, Mehrabi, Arianeb, Singer, Stephan, Vogel, Monika Nadja, Neumann, Olaf, Stenzinger, Albrecht, Schirmacher, Peter, Weis, Cleo-Aron, Roessler, Stephanie, Kather, Jakob Nikolas, and Goeppert, Benjamin

Published
2023
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25. Revival of associating liver partition and portal vein ligation for staged hepatectomy for perihilar cholangiocarcinoma: An international multicenter study with promising outcomes

Author

Balci, Deniz, Nadalin, Silvio, Mehrabi, Arianeb, Alikhanov, Ruslan, Fernandes, Eduardo S.M., Di Benedetto, Fabrizio, Hernandez-Alejandro, Roberto, Björnsson, Bergthor, Efanov, Mikhail, Capobianco, Ivan, Clavien, Pierre-Alain, Kirimker, Elvan Onur, and Petrowsky, Henrik

Published
2023
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26. Surgical outcomes of gallbladder cancer: the OMEGA retrospective, multicentre, international cohort study

Author

Abe, Tomoyuki, Abu Hilal, Moh'd, Achalandabaso Boira, Maria del Mar, Adham, Mustapha, Adam, Mohamed, Ahmad, Maryam, Al-Sarireh, Bilal, Albiol, Maite, Alhaboob, Nassir, Alseidi, Adnan, Ammar, Houssem, Anand, Akshay, Andersson, Bodil, Antonakis, Pantelis, Araya, Veronica, Ashley, Stanley W., Atanasov, Georgi, Ausania, Fabio, Balestri, Ricardo, Banerjee, Abhirup, Banerjee, Sudeep, Banting, Simon, Barauskas, Giedrius, Bartsch, Fabian, Belli, Andrea, Beretta, Simona, Berrevoet, Frederik, Bhandari, Ramesh Singh, Blanco Fernandez, Gerardo, Bolm, Louisa, Bonal, Mathieu, Bozkurt, Emre, Braat, Andries E., Bradshaw, Luke, Bramis, Konstantinos, Branes, Alejandro, Burdine, Lyle, Byrne, Matthew, Caceres, Maria, Castro Santiago, Maria Jesus, Chan, Benjamin, Chong, Lynn, Çoker, Ahmet, Conde Rodriguez, Maria, Croagh, Daniel, Crutchley, Alyn, Cutolo, Carmen, D'Hondt, Mathieu, D'Souza, Daniel, Daams, Freek, Dalla Valle, Raffaele, Davide, José, de Bellis, Mario, de Boer, Marieke, de Meyere, Celine, de Reuver, Philip, Dixon, Matthew, Dorovinis, Panagiotis, Echeverría Bauer, Gabriela, Eduarda, Maria, Eker, Hasan, Erdmann, Joris, Erkan, Mert, Felekouras, Evangelos, Felli, Emanuele, Fernandes, Eduardo, Figueroa Rivera, Eduardo, Fulop, Andras, Galun, Daniel, Gerhards, Michael, Ghorbani, Poya, Giannone, Fabio, Gil, Luis, Giorgakis, Emmanouil, Giuffrida, Mario, Giuliante, Felice, Gkekas, Ioannis, Gomez Bravo, Miguel, Groot Koerkamp, Bas, Guevara, Oscar, Guglielmi, Alfredo, Gulla, Aiste, Gupta, Rahul, Gupta, Amit, Gutiérrez, Marta, Hafeez Bhatti, Abu Bakar, Hagendoorn, Jeroen, Hajee, Zain, Hakeem, Abdul Rahman, Hamid, Hytham, Hassen, Sayed, Heinrich, Stefan, Higuchi, Ryota, Hoffman, Daniel, Holroyd, David, Hughes, Daniel, Ivanecz, Arpad, Iype, Satheesh, Jaen Torrejimeno, Isabel, Joglekar, Shantanu, Jones, Robert, Kaczirek, Klaus, Kanhere, Harsh, Kausar, Ambareen, Kee, Zhanyi, Keilson, Jessica, Kleef, Jorg, Klose, Johannes, Knowles, Brett, Koong, Jun Kit, Kumar, Nagappan, Kunnuru, Supreeth, Lakhey, Paleswan Joshi, Laurenzi, Andrea, Lee, Yeong Sing, Leon, Felipe, Leow, Voon Meng, Lequeu, Jean-Baptiste, Lesurtel, Mickael, Lo, Elisabeth, Löb, Stefan, Lockie, Elizabeth, Lodge, Peter, López Garnica, Dolores, Lopez Lopez, Victor, Lundgren, Linda, Machairas, Nikolaos, Maharjan, Dhiresh, Malde, Deep, Martel, Guillaume, Martin, Julie, Mazzola, Michele, Mehrabi, Arianeb, Memeo, Ricardo, Milana, Flavio, Molina, George, Monette, Leah, Morgul, Haluk, Moris, Dimitrios, Morsi-Yeroyannis, Antonios, Mowbray, Nicholas, Mulita, Francesk, Muttillo, Edoardo Maria, Nandasena, Malith, Nashidengo, Pueya Rashid, Nickkholgh, Arash, Noel, Colin Byron, Ohtsuka, Masayuki, Ozolins, Arturs, Pandanaboyana, Sanjay, Pararas, Nikolaos, Parente, Alessandro, Peng, June, Perfecto Valero, Arkaitz, Perinel, Julie, Perivoliotis, Konstatinos, Perra, Teresa, Pessaux, Patrick, Petruch, Natalie, Piccolo, Gaetano, Piros, Laszlo, Porcu, Alberto, Prabakaran, Viswakumar, Prasad, Raj, Prieto Calvo, Mikel, Primavesi, Florian, Pueyo Periz, Eva Maria, Quaglia, Alberto, Ramia Angel, Jose M., Rammohan, Ashwin, Razionale, Francesco, Robles Campos, Ricardo, Roy, Manas, Rozwadowski, Sophie, Ruffolo, Luis, Ruiz, Natalia, Ruzzenante, Andrea, Saadat, Lily, Said, Mohamed Amine, Saladino, Edoardo, Saliba, Gabriel, Sandstrom, Per, Schena, Carlo Alberto, Scholer, Anthony, Schwarz, Christoph, Serafini, Lorenzo, Serrano, Pablo E., Sharma, Deepak, Sheen, Aali, Siddagangaiah, Vishwanath, Silva, Michael, Singh, Saurabh, Siriwardena, Ajith, Skalski, Michal, Smig, Mante, Soliman, Faris, Sonkar, Abhinav Arun, Sousa Silva, Donzília, Sparrelid, Ernesto, Srinivasan, Parthi, Sternby Eilard, Malin, Strobel, Oliver, Stupan, Urban, Suarez-Munoz, Miguel Angel, Subramaniam, Manisekar, Sugiura, Teiichi, Sutcliffe, Robert, Swank, Hilko, Taylor, Lillian, Thapa, Prabin Bikram, The, Catherine, Thepbunchonchai, Asara, Thieu, Caman, Tiwari, Navneet, Torzilli, Guido, Tovikkai, Chutwichai, Trotovsek, Blaz, Tsaramanidis, Savvas, Tsoulfas, Georgios, Uesaka, Katsuhiko, Umar, Garzali, Urbani, Lucio, Vailas, Michail, van Dam, Ronald, van de Boezem, Peter, van Laarhoven, Stijn, Vanagas, Tomas, Van Dooren, Mike, Viennet, Manon, Vigano, Luca, Vijayashanker, Aarathi, Villodre, Celia, Wakai, Toshifumi, Workneh, Aklile, Xu, Li, Yamamoto, Masakazu, Yang, Zhiying, Young, Robert, Zivanovic, Marko, Balakrishnan, Anita, Barmpounakis, Petros, Demiris, Nikolaos, Jah, Asif, Spiers, Harry V.M., Talukder, Shibojit, Martin, Jack L., Gibbs, Paul, Harper, Simon J.F., Huguet, Emmanuel L., Kosmoliaptsis, Vasilis, Liau, Siong S., Praseedom, Raaj K., Basu, Bristi, de Aretxabala, Xavier, Lendoire, Javier, Maithel, Shishir, Serrablo, Alejandro, and Adsay, Volkan

Published
2023
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31. Development of biotissue training models for anastomotic suturing in pancreatic surgery

Author

Karadza, Emir, Haney, Caelan M., Limen, Eldridge F., Müller, Philip C., Kowalewski, Karl-Friedrich, Sandini, Marta, Wennberg, Erica, Schmidt, Mona W., Felinska, Eleni A., Lang, Franziska, Salg, Gabriel, Kenngott, Hannes G., Rangelova, Elena, Mieog, Sven, Vissers, Frederique, Korrel, Maarten, Zwart, Maurice, Sauvanet, Alain, Loos, Martin, Mehrabi, Arianeb, de Santibanes, Martin, Shrikhande, Shailesh V., Abu Hilal, Mohammad, Besselink, Marc G., Müller-Stich, Beat P., Hackert, Thilo, and Nickel, Felix

Published
2023
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38. Completion Pancreatectomy After Pancreatoduodenectomy: Who Needs It?

Author

Loos, Martin, König, Anna-Katharina, von Winkler, Nikolai, Mehrabi, Arianeb, Berchtold, Christoph, Müller-Stich, Beat P., Schneider, Martin, Hoffmann, Katrin, Kulu, Yakup, Feisst, Manuel, Hinz, Ulf, Lang, Matthias, Goeppert, Benjamin, Albrecht, Thomas, Strobel, Oliver, Büchler, Markus W., and Hackert, Thilo

Published
2023
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46. Impact of deceased-donor characteristics on early graft function: outcome of kidney donor pairs accepted for transplantation.

Author

Mahler, Christoph F., Friedl, Felix, Nusshag, Christian, Speer, Claudius, Benning, Louise, Göth, Daniel, Schaier, Matthias, Sommerer, Claudia, Mieth, Markus, Mehrabi, Arianeb, Renders, Lutz, Heemann, Uwe, Krautter, Markus, Schwenger, Vedat, Echterdiek, Fabian, Zeier, Martin, Morath, Christian, and Kälble, Florian

Subjects
GENERALIZED estimating equations, GRAFT survival, GLOMERULAR filtration rate, BODY mass index, KIDNEY transplantation
Abstract

Introduction: The impact of deceased donor characteristics on kidney transplant outcomes is controversial. Correspondingly, the predictive performance of deceased donor scores remains moderate, and many transplant centers lack validated criteria for graft acceptance decisions. To better dissect donor-related risk from recipient and periprocedural variables, we analyzed outcomes of kidney donor pairs transplanted in different individuals. Methods: This study explored (a)symmetry of early outcomes of 328 cadaveric kidney transplant recipients from 164 donor pairs transplanted at three Eurotransplant centers. The primary discriminatory factor was (a)symmetry of partner graft function, defined as early graft loss or impaired graft function [estimated glomerular filtration rate (eGFR) <30 mL/min] 3 months after transplantation. We reasoned that a relevant impact of donor factors would result in a high concordance rate of limited graft function or failure. Results: The observed number of symmetric graft failure after transplantation was less than statistically expected (3 months: 1 versus 2, p = 0.89; and 12 months: 3 versus 5, p = 0.26). However, we found a trend toward an impaired 5-year graft survival of grafts with good function 3 months after transplantation but a failed or impaired partner graft compared to symmetrically well-functioning grafts (p = 0.09). Subsequently, we explored the impact of individual donor and recipient variables on early transplant outcomes. Generalized estimating equations after feature selection with LassoGEE bootstrap selected donor age, donor body mass index, and donor eGFR as the relevant risk factors. Discussion: Our findings indicate that donor factors impact early outcomes in kidney transplantation but may have a limited role in long-term graft survival, once a graft has been accepted for transplantation. Utilizing donor-based clinical scores has the potential to aid clinicians in acceptance decisions, giving them an estimate of individual posttransplant outcomes. However, the ultimate decision for acceptance should rest with clinicians, who must consider the complex interplay of donor factors, as well as recipient and periprocedural characteristics. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Preoperative Inflammatory Scores Do Not Accurately Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma After Resection: A Systematic Review and Meta‐Analysis.

Author

de Castro e Borges, Filipe, Khajeh, Elias, Nikbakhsh, Rajan, Ribeiro, Catarina, Maeurer, Markus, Carvalho, Carlos, Gonçalves, Gil, Berchtold, Christoph, Büchler, Markus W., and Mehrabi, Arianeb

Abstract

Background: Disease recurrence after surgical resection for pancreatic ductal adenocarcinoma can affect more than 50% of patients in the first 12 months after resection. The goal of this current systematic review and meta‐analysis is to assess the ability of preoperative inflammatory scores to predict early recurrence after resection and to identify the best candidates for surgical resection. Methods: Medline and Web of Science databases were searched for studies reporting inflammatory scores and oncological outcomes in patients with PDAC after curative‐intent resection. The systematic review revealed that the most common scores were modified Glasgow Prognostic Score (mGPS), Prognostic Nutritional Index (PNI), platelet‐to‐lymphocyte ratio (PLR), neutrophil‐to‐lymphocyte ratio (NLR), and Systemic Immune‐Inflammation Index (SII). After, a meta‐analysis was performed to determine the prognostic value of these scores in early recurrence (12 months) after resection. A subgroup analysis was also carried out in patients who had upfront surgery and in those who underwent neoadjuvant chemotherapy. The ROBINS‐I tool was used to assess the risk of bias. Results: The literature search retrieved 1864 articles, 16 of which were eligible for analysis. The included studies comprised 4460 patients. Nine studies reported outcomes for mGPS, four studies for PNI, seven studies for PLR, eight studies for NLR, and two studies for SII. In the meta‐analysis, mGPS, NLR, and PLR showed significantly higher rates of early recurrence in the high‐score groups compared to the low‐score groups. Analyzing the sensitivity and specificity of these scores showed no significant difference in their diagnostic accuracy (mGPS area under the curve [AUC] = 0.534; NLR AUC = 0.628, and PLR AUC = 0.607). High and low PNI and SII scores demonstrated similar rates of early recurrence. Conclusion: mGPS, PNI, PLR, NLR, and SII scores did not show a suitable diagnostic accuracy to predict PDAC recurrence in the first 12 months after resection. Therefore, these inflammatory scores should not be used to select the best candidates or to preclude a possible surgical indication. [ABSTRACT FROM AUTHOR]

Published
2024
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49. Modified Peritoneal Fenestration as a Preventive Method for Lymphocele after Kidney Transplantation: A Preliminary Report.

Author

Sabagh, Mohammadsadegh, Weber, Sanaz, Sabetkish, Nastaran, Ramouz, Ali, Fakour, Sanam, Morath, Christian, Mieth, Markus, Zeier, Martin, Khajeh, Elias, Mehrabi, Arianeb, and Golriz, Mohammad

Subjects
BODY mass index, LYMPHOCELE, ABDOMINAL surgery, UNIVARIATE analysis, CLINICAL trials, KIDNEY transplantation
Abstract

Background: We aimed to assess the safety of a modified peritoneal fenestration technique with clipping of the window edges during kidney transplantation (KTx) and to determine its impact on reducing lymphocele following KTx. We compared the outcomes of this modified method with those of peritoneal fenestration without clipping. Methods: Among 430 consecutive KTxs performed between 2015 and 2019, preventive peritoneal fenestration and clipping of the margins were performed in 25 patients. These patients were compared with 75 matched patients in whom the margins were not clipped. Postoperative lymphocele formation and other patient data were compared between these two groups. Results: The rate of clinically relevant lymphocele decreased by 2.7% after peritoneal fenestration with clipping, although this decrease was not statistically significant (p = 0.829). There was no significant increase in the rate of other complications in the modified fenestration group (p = 0.067). The incidence of clinically significant lymphocele formation was notably higher in patients with a body mass index greater than 25 kg/m2 (p = 0.028). Univariate analysis indicated that older recipients, individuals with a history of previous abdominal surgery, those receiving the kidney from deceased and older donors were at increased risk of developing a clinically relevant lymphocele. Conclusions: Our preliminary results suggest that peritoneal fenestration with clipping may be as effective as the conventional fenestration technique in preventing lymphocele formation. Further clinical trials with larger sample sizes are required to determine the exact role of preventive peritoneal fenestration with clipping in preventing clinically relevant lymphocele after KTx. [ABSTRACT FROM AUTHOR]

Published
2024
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