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Introduction: From a long time ago, preterm birth has posed life-threatening risks due to the significant complications it causes. The present study aimed to examine how the lifestyle of pregnant women is related to the incidence of preterm birth. Materials and Methods: For this cohort study, a total of 234 individuals with healthy and unhealthy lifestyles who visited the women's clinics of Azad University hospitals during the year 2021 were randomly selected to participate. Four criteria were utilized to build lifestyle questionnaires, which included smoking habits, physical activity levels, consumption of high-fiber foods, and sufficient sleep. According to the individuals' responses, 117 mothers who scored above 14, and 117 mothers who scored below 14 were followed up. The SPSS version 25 (SPSS Inc., Chicago, Ill., USA) was used to analyze the correlation between variables and preterm birth, employing statistical tests such as Mann-Whitney, Chi-square, and independent t-test. Results: In this study, the mean age of the examined women was 27.11 ± 3.19. Out of the total number of babies, 133 (56.8%) were females, while 101 (43.2%) were males. The P value for the association between lifestyle and preterm birth was less than 0.0001, indicating statistical significance. The difference between the consumption of tobacco, fruits, and vegetables and sufficient sleep with preterm birth was not statistically significant (P value >0.05). Conclusion: A healthy lifestyle can serve as an important preventive measure against preterm birth. Adequate education provided by the healthcare and treatment system plays an important role in promoting the adoption of a healthy lifestyle and benefiting from its positive outcomes.

Background and Purpose: Urinary incontinence (URIN) and fecal incontinence (FEIN) are common in women, which affect various aspects of their daily life and general health. Therefore, the main purpose of this study was to evaluate the effect of biofeedback (BFB) in women with urinary and FEIN referring to the hospitals of Islamic Azad University of Medical Sciences, Tehran branch, Iran (2021). Materials and Methods: This research was a cohort study that was conducted on 100 women with urinary and FEIN who were referred to selected hospitals of the Islamic Azad University of Medical Sciences, Tehran branch. In this study, before and after BFB, the amount of urinary and FEIN in patients was measured and finally compared by SPSS-ver. 16 software. Results: The results of this study showed that the frequency of patients with URIN and FEIN was equal to 66 (66%) and 34 (66%) patients, respectively. After treatment with BFB, 39 (59.1%) patients with URIN and 39 (59.1%) patients with FEIN had symptom improvement. The mean body mass index and the number of pregnancies in patients who improved urinary and FEIN symptoms after BFB were significantly lower than in patients who did not improve symptoms. Conclusion: Based on the findings of the present study, it can be concluded that effective and significant factors on the improvement of urinary and FEIN symptoms after BFB include fiber consumption, the presence of underlying diseases such as diabetes, blood pressure, type of delivery, history of depression, history of anorectal surgery, and vaginal delivery was difficult. In addition, based on the findings of the study, it can be said that BFB has an acceptable effect in improving the symptoms of urinary and FEIN in women, although additional studies are needed to confirm the results.

Background and Objectives: Studies have indicated that the chronic use of morphine can result in physical and psychological dependence. Morphine dependence is associated with several cellular and molecular alterations in the mesocorticolimbic system, and striatal dopamine signaling is involved in this process. In the present study, we aim to investigate possible alterations in the level of dopamine receptors DRD2 and DRD4 in the striatum of male rats following chronic oral administration of morphine and assess the effect of subcutaneous injection of memantine on morphine-induced effects. Methods: In this experimental study, 16 male Wistar rats were randomly divided into four groups: Control, morphine, memantine, and morphine+memantine. The morphine group received increasing doses of morphine (0.1-0.4 mg/kg) via their drinking water for 21 consecutive days. The memantine groups, after receiving distilled water without morphine for 21 days, received a subcutaneous injection of 5 mg memantine. The morphine memantine group received 5 mg of memantine subcutaneously on day 21 and 30 minutes after the last oral administration of morphine. After collecting striatum tissue, dopamine receptor levels were evaluated by the western blotting method. Results: The chronic use of morphine increased the levels of DRD2 and DRD4 compared to the controls. Memantine administration also increased the level of these receptors compared to the controls. In addition, the expression of DRD2 and DRD4 increased in the morphine+ memantine group compared to the memantine group. Conclusion: Morphine affects the expression of dopamine receptors in the striatum. Treatment with memantine can increases dopamine receptors’ expression.