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339 results on '"Mearin, M Luisa"'

3. Prediction Models for Celiac Disease Development in Children From High-Risk Families: Data From the PreventCD Cohort

Author

Meijer, Caroline R., Auricchio, Renata, Putter, Hein, Castillejo, Gemma, Crespo, Paula, Gyimesi, Judit, Hartman, Corina, Kolacek, Sanja, Koletzko, Sibylle, Korponay-Szabo, Ilma, Ojinaga, Eva Martinez, Polanco, Isabel, Ribes-Koninckx, Carmen, Shamir, Raanan, Szajewska, Hania, Troncone, Riccardo, Villanacci, Vincenzo, Werkstetter, Katharina, and Mearin, M. Luisa

Published
2022
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6. Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis

Author

Joosse, Maria E., Charbit-Henrion, Fabienne, Boisgard, Remy, Raatgeep, Rolien (H.) C., Lindenbergh-Kortleve, Dicky J., Costes, Léa M.M., Nugteren, Sandrine, Guegan, Nicolas, Parlato, Marianna, Veenbergen, Sharon, Malan, Valérie, Nowak, Jan K., Hollink, Iris H. I.M., Mearin, M. Luisa, Escher, Johanna C., Cerf-Bensussan, Nadine, and Samsom, Janneke N.

Published
2021
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9. Early diet and the risk of coeliac disease. An update 2024 position paper by the ESPGHAN special interest group on coeliac disease.

Author

Szajewska, Hania, Shamir, Raanan, Auricchio, Renata, Chmielewska, Anna, Dolinsek, Jernej, Kivelä, Laura, Koletzko, Sibylle, Korponay‐Szabo, Ilma R., Af Segerstad, Elin M Hård, Mearin, M. Luisa, Meijer‐Boekel, Caroline, Konickx, Carmen Ribes, Rodriguez‐Herrera, Alfonso, Stordal, Ketil, Troncone, Riccardo, and Wessels, Margreet

Published
2024
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10. Raising the Cut-Off Level of Anti-Tissue Transglutaminase Antibodies to Detect Celiac Disease Reduces the Number of Small Bowel Biopsies in Children with Type 1 Diabetes: A Retrospective Study

Author

Wessels, Margreet, Velthuis, Anouk, van Lochem, Ellen, Duijndam, Eline, Hoorweg-Nijman, Gera, de Kruijff, Ineke, Wolters, Victorien, Berghout, Eveline, Meijer, Jos, Bokma, Jan Alle, Mul, Dick, van der Velden, Janielle, Roovers, Lian, Mearin, M. Luisa, and van Setten, Petra

Published
2020
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12. E-Healthcare for Celiac Disease—A Multicenter Randomized Controlled Trial

Author

Vriezinga, Sabine, Borghorst, Annelise, van den Akker-van Marle, Elske, Benninga, Marc, George, Elvira, Hendriks, Danielle, Hopman, Erica, de Meij, Tim, van der Meulen-de Jong, Andrea, Putter, Hein, Rings, Edmond, Schaart, Maaike, Schweizer, Joachim, Smit, Margot, Tabbers, Merit, Weijerman, Michel, Wessels, Margreet, and Mearin, M. Luisa

Published
2018
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14. Multiple common variants for celiac disease influencing immune gene expression

Author

Dubois, Patrick CA, Trynka, Gosia, Franke, Lude, Hunt, Karen A, Romanos, Jihane, Curtotti, Alessandra, Zhernakova, Alexandra, Heap, Graham AR, Ádány, Róza, Aromaa, Arpo, Bardella, Maria Teresa, van den Berg, Leonard H, Bockett, Nicholas A, de la Concha, Emilio G, Dema, Bárbara, Fehrmann, Rudolf SN, Fernández-Arquero, Miguel, Fiatal, Szilvia, Grandone, Elvira, Green, Peter M, Groen, Harry JM, Gwilliam, Rhian, Houwen, Roderick HJ, Hunt, Sarah E, Kaukinen, Katri, Kelleher, Dermot, Korponay-Szabo, Ilma, Kurppa, Kalle, MacMathuna, Padraic, Mäki, Markku, Mazzilli, Maria Cristina, McCann, Owen T, Mearin, M Luisa, Mein, Charles A, Mirza, Muddassar M, Mistry, Vanisha, Mora, Barbara, Morley, Katherine I, Mulder, Chris J, Murray, Joseph A, Núñez, Concepción, Oosterom, Elvira, Ophoff, Roel A, Polanco, Isabel, Peltonen, Leena, Platteel, Mathieu, Rybak, Anna, Salomaa, Veikko, Schweizer, Joachim J, Sperandeo, Maria Pia, Tack, Greetje J, Turner, Graham, Veldink, Jan H, Verbeek, Wieke HM, Weersma, Rinse K, Wolters, Victorien M, Urcelay, Elena, Cukrowska, Bozena, Greco, Luigi, Neuhausen, Susan L, McManus, Ross, Barisani, Donatella, Deloukas, Panos, Barrett, Jeffrey C, Saavalainen, Paivi, Wijmenga, Cisca, and van Heel, David A

Subjects
Biotechnology, Human Genome, Genetics, Digestive Diseases, 2.1 Biological and endogenous factors, Aetiology, Case-Control Studies, Celiac Disease, Gene Expression, Gene Expression Profiling, Genes, MHC Class I, Genome-Wide Association Study, Humans, Meta-Analysis as Topic, Polymorphism, Single Nucleotide, Risk, Biological Sciences, Medical and Health Sciences, Developmental Biology
Abstract

We performed a second-generation genome-wide association study of 4,533 individuals with celiac disease (cases) and 10,750 control subjects. We genotyped 113 selected SNPs with P(GWAS) < 10(-4) and 18 SNPs from 14 known loci in a further 4,918 cases and 5,684 controls. Variants from 13 new regions reached genome-wide significance (P(combined) < 5 x 10(-8)); most contain genes with immune functions (BACH2, CCR4, CD80, CIITA-SOCS1-CLEC16A, ICOSLG and ZMIZ1), with ETS1, RUNX3, THEMIS and TNFRSF14 having key roles in thymic T-cell selection. There was evidence to suggest associations for a further 13 regions. In an expression quantitative trait meta-analysis of 1,469 whole blood samples, 20 of 38 (52.6%) tested loci had celiac risk variants correlated (P < 0.0028, FDR 5%) with cis gene expression.

Published
2010

20. European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020

Author

Husby, Steffen, Koletzko, Sibylle, Korponay-Szabó, Ilma, Kurppa, Kalle, Mearin, M. Luisa, Ribes-Koninckx, Carmen, Shamir, Raanan, Troncone, Riccardo, Auricchio, Renata, Castillejo, Gemma, Christensen, Robin, Dolinsek, Jernej, Gillett, Peter, Hróbjartsson, Asbjørn, Koltai, Tunde, Maki, Markku, Nielsen, Sabrina Mai, Popp, Alina, Størdal, Ketil, Werkstetter, Katharina, and Wessels, Margreet

Published
2020
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22. Coeliac disease

Author

Lindfors, Katri, Ciacci, Carolina, Kurppa, Kalle, Lundin, Knut E. A., Makharia, Govind K., Mearin, M. Luisa, Murray, Joseph A., Verdu, Elena F., and Kaukinen, Katri

Published
2019
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27. Corrigendum to Raising the Cut-Off Level of Anti-Tissue Transglutaminase Antibodies to Detect Celiac Disease Reduces the Number of Small Bowel Biopsies in Children with Type 1 Diabetes: A Retrospective Study. The Journal of Pediatrics Volume 223, August 2020, Pages 87-92.e1

Author

Wessels, Margreet, primary, Velthuis, Anouk, additional, van Lochem, Ellen, additional, Duijndam, Eline, additional, Hoorweg-Nijman, Gera, additional, de Kruijff, Ineke, additional, Wolters, Victorien, additional, Berghout, Eveline, additional, Meijer, Jos, additional, Bokma, Jan Alle, additional, Mul, Dick, additional, van der Velden, Janielle, additional, Roovers, Lian, additional, Mearin, M. Luisa, additional, and van Setten, Petra, additional

Published
2022
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28. Identification of a Disease-Associated Network of Intestinal Immune Cells in Treatment-Naive Inflammatory Bowel Disease

Author

van Unen, Vincent, primary, Ouboter, Laura F., additional, Li, Na, additional, Schreurs, Mette, additional, Abdelaal, Tamim, additional, Kooy-Winkelaar, Yvonne, additional, Beyrend, Guillaume, additional, Höllt, Thomas, additional, Maljaars, P. W. Jeroen, additional, Mearin, M. Luisa, additional, Mahfouz, Ahmed, additional, Witte, Anne M. C., additional, Clemens, Cornelis H. M., additional, Abraham, Sunje, additional, Escher, Johanna C., additional, Lelieveldt, Boudewijn P. F., additional, Pascutti, M. Fernanda, additional, van der Meulen – de Jong, Andrea E., additional, and Koning, Frits, additional

Published
2022
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29. Systematic review : early feeding practices and the risk of coeliac disease. A 2022 update and revision

Author

Szajewska, Hania, Shamir, Raanan, Stróżyk, Agata, Chmielewska, Anna, Zalewski, Bartłomiej M., Auricchio, Renata, Koletzko, Sibylle, Korponay-Szabo, Ilma R., Mearin, M. Luisa, Meijer, Caroline, Ribes-Koninckx, Carmen, Troncone, Riccardo, Szajewska, Hania, Shamir, Raanan, Stróżyk, Agata, Chmielewska, Anna, Zalewski, Bartłomiej M., Auricchio, Renata, Koletzko, Sibylle, Korponay-Szabo, Ilma R., Mearin, M. Luisa, Meijer, Caroline, Ribes-Koninckx, Carmen, and Troncone, Riccardo

Abstract

Background: The effects of early feeding practices on the risk of coeliac disease (CD) remain debated. Aims: To update evidence on these practices on the risk of CD and/or CD-related autoimmunity (CDA), defined as anti-transglutaminase or anti-endomysial antibody positivity. Methods: We searched MEDLINE, EMBASE and the Cochrane Library to May 2022 for randomised controlled trials (RCTs) and observational studies. Results: We included 36 publications (30 studies). In the population at genetic risk of developing CD (HLA DQ2/DQ8-positive), exclusive or any breastfeeding and longer breastfeeding duration did not reduce the risk of developing CD/CDA during childhood. While a meta-analysis of four case–control studies showed a decreased risk for CD when gluten was introduced during breastfeeding, this was not shown in RCTs and cohort studies. Age at gluten introduction was not associated with cumulative CD/CDA risk, although two RCTs suggested that earlier gluten introduction was associated with earlier CDA appearance. Evidence from six observational studies suggests that consumption of a higher amount of gluten at weaning and/or thereafter may increase CD risk. There is insufficient evidence to determine the amount of gluten associated with an increased CD/CDA risk. Regarding whether infant feeding practices modulate the risk conferred by different HLA genotypes results were inconsistent. Conclusions: For the population at genetic risk of CD, breastfeeding and age at gluten introduction have no effect on its cumulative incidence during childhood. There is some evidence for an effect of the amount of gluten consumed at weaning and/or thereafter on CD/CDA risk.

Published
2022
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30. Corrigendum to Raising the Cut-Off Level of Anti-Tissue Transglutaminase Antibodies to Detect Celiac Disease Reduces the Number of Small Bowel Biopsies in Children with Type 1 Diabetes: A Retrospective Study. The Journal of Pediatrics Volume 223, August 2020, Pages 87-92.e1 (The Journal of Pediatrics (2020) 223 (87–92.e1), (S002234762030319X), (10.1016/j.jpeds.2020.02.086))

Author

MDL, Child Health, Pathologie Pathologen staf, Wessels, Margreet, Velthuis, Anouk, van Lochem, Ellen, Duijndam, Eline, Hoorweg-Nijman, Gera, de Kruijff, Ineke, Wolters, Victorien, Berghout, Eveline, Meijer, Jos, Bokma, Jan Alle, Mul, Dick, van der Velden, Janielle, Roovers, Lian, Mearin, M. Luisa, van Setten, Petra, MDL, Child Health, Pathologie Pathologen staf, Wessels, Margreet, Velthuis, Anouk, van Lochem, Ellen, Duijndam, Eline, Hoorweg-Nijman, Gera, de Kruijff, Ineke, Wolters, Victorien, Berghout, Eveline, Meijer, Jos, Bokma, Jan Alle, Mul, Dick, van der Velden, Janielle, Roovers, Lian, Mearin, M. Luisa, and van Setten, Petra

Published
2022

34. Circulating miRNAs as Potential Biomarkers for Celiac Disease Development

Author

Tan, Ineke L., primary, Coutinho de Almeida, Rodrigo, additional, Modderman, Rutger, additional, Stachurska, Anna, additional, Dekens, Jackie, additional, Barisani, Donatella, additional, Meijer, Caroline R., additional, Roca, María, additional, Martinez-Ojinaga, Eva, additional, Shamir, Raanan, additional, Auricchio, Renata, additional, Korponay-Szabó, Ilma R., additional, Castillejo, Gemma, additional, Szajewska, Hania, additional, Koletzko, Sibylle, additional, Zhernakova, Alexandra, additional, Kumar, Vinod, additional, Li, Yang, additional, Visschedijk, Marijn C., additional, Weersma, Rinse K., additional, Troncone, Riccardo, additional, Mearin, M. Luisa, additional, Wijmenga, Cisca, additional, Jonkers, Iris, additional, and Withoff, Sebo, additional

Published
2021
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36. Systematic review: early feeding practices and the risk of coeliac disease. A 2022 update and revision.

Author

Szajewska, Hania, Shamir, Raanan, Stróżyk, Agata, Chmielewska, Anna, Zalewski, Bartłomiej M., Auricchio, Renata, Koletzko, Sibylle, Korponay‐Szabo, Ilma R., Mearin, M. Luisa, Meijer, Caroline, Ribes‐Koninckx, Carmen, and Troncone, Riccardo

Subjects
CELIAC disease, INFANTS, ANIMAL feeds, RANDOMIZED controlled trials, GLUTEN
Abstract

Summary: Background: The effects of early feeding practices on the risk of coeliac disease (CD) remain debated. Aims: To update evidence on these practices on the risk of CD and/or CD‐related autoimmunity (CDA), defined as anti‐transglutaminase or anti‐endomysial antibody positivity Methods: We searched MEDLINE, EMBASE and the Cochrane Library to May 2022 for randomised controlled trials (RCTs) and observational studies. Results: We included 36 publications (30 studies). In the population at genetic risk of developing CD (HLA DQ2/DQ8‐positive), exclusive or any breastfeeding and longer breastfeeding duration did not reduce the risk of developing CD/CDA during childhood. While a meta‐analysis of four case–control studies showed a decreased risk for CD when gluten was introduced during breastfeeding, this was not shown in RCTs and cohort studies. Age at gluten introduction was not associated with cumulative CD/CDA risk, although two RCTs suggested that earlier gluten introduction was associated with earlier CDA appearance. Evidence from six observational studies suggests that consumption of a higher amount of gluten at weaning and/or thereafter may increase CD risk. There is insufficient evidence to determine the amount of gluten associated with an increased CD/CDA risk. Regarding whether infant feeding practices modulate the risk conferred by different HLA genotypes results were inconsistent. Conclusions: For the population at genetic risk of CD, breastfeeding and age at gluten introduction have no effect on its cumulative incidence during childhood. There is some evidence for an effect of the amount of gluten consumed at weaning and/or thereafter on CD/CDA risk. [ABSTRACT FROM AUTHOR]

Published
2023
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37. Early diagnosis of coeliac disease in the Preventive Youth Health Care Centres in the Netherlands: study protocol of a case finding study (GLUTENSCREEN)

Author

Meijer-Boekel, Caroline, primary, van den Akker, M.Elske, additional, van Bodegom, Leti, additional, Escher, Johanna, additional, van Geloven, Nan, additional, van Overveld, Floris, additional, Rings, Edmond H H.M, additional, Smit, Lucy, additional, de Vries, Martine Charlotte, additional, and Mearin, M. Luisa, additional

Published
2021
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39. Randomized Feeding Intervention in Infants at High Risk for Celiac Disease

Author

Vriezinga, Sabine L., Auricchio, Renata, Bravi, E., Castillejo, Gemma, Chmielewska, Anna, Crespo Escobar, Paula, Kolaček, Sanja, Koletzko, Sibylle, Korponay-Szabo, Ilma R., Mummert, Eckart, Polanco, Isabel, Putter, Hein, Ribes-Koninckx, Carmen, Shamir, Raanan, Szajewska, Hania, Werkstetter, Katharina, Greco, Luigi, Gyimesi, Judit, Hartman, Corina, Hogen Esch, Caroline, Hopman, Erica, Ivarsson, Anneli, Koltai, Tunde, Koning, Frits, Martinez-Ojinaga, Eva, te Marvelde, Chantal, Pavic, Ana, Romanos, Jihane, Stoopman, Els, Villanacci, Vincenzo, Wijmenga, Cisca, Troncone, Ricardo, and Mearin, M. Luisa

Published
2014
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40. Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

Author

Romanos, Jihane, Rosén, Anna, Kumar, Vinod, Trynka, Gosia, Franke, Lude, Szperl, Agata, Gutierrez-Achury, Javier, van Diemen, Cleo C, Kanninga, Roan, Jankipersadsing, Soesma A, Steck, Andrea, Eisenbarth, Georges, van Heel, David A, Cukrowska, Bozena, Bruno, Valentina, Mazzilli, Maria Cristina, Núñez, Concepcion, Bilbao, Jose Ramon, Mearin, M Luisa, Barisani, Donatella, Rewers, Marian, Norris, Jill M, Ivarsson, Anneli, Boezen, H Marieke, Liu, Edwin, Wijmenga, Cisca, Scerri, Cristian, Koltai, Tunde, Kolaček, Sanja, Mišak, Zrinka, Abdović, Slaven, Koletzko, Sibylle, Osiander, Gertraud, Werkstetter, Katharina, Mummert, Eckart, Korponay-Szabo, Ilma R, Gyimesi, Judit, Shamir, Raanan, Hartman, Corina, Bravi, Enzo, Poles, Marco, Auricchio, Renata, Limongelli, G Gianna Giovamma, Greco, Luigi, Troncone, Riccardo, Villanacci, Vincenzo, Bindels, Jacques G, Brand, Ronald, Kupper, Bibi Funke, Esch, Caroline E Hogen, Hopman, Erica G, Koning, Frits, Kooy-Winkelaar, Yvonne, te Marvelde, Chantal, Putter, Hein, Stoopman, Els, Vriezinga, Sabine, Sollid, Ludvig M, Ráki, Melinda, Chmielewska, Ania, Dziechciarz, Piotr, Pieścik-Lech, Małgorzata, Szajewska, Hania, Szaflarska-Szczepanik, Anna, Castillejo, Gemma, Capilla, Amalia, Varea, Vicente, Ribes-Koninckx, Carmen, Lopez, Anna, Crespo, Paula, Martinez, Eva, Polanco, Isabel, Högberg, Lotta, Stenhammar, Lars, Carlsson, Annelie, Webb, Charlotta, Hammarroth, Solveig, Hernell, Olle, Lagerqvist, Carina, Myléus, Anna, Nordyke, Katrina, Norström, Fredrik, Sandström, Olof, Wall, Stig, and Karlsson, Eva

Published
2014
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41. Presence and Levels of Galactosyllactoses and Other Oligosaccharides in Human Milk and Their Variation during Lactation and According to Maternal Phenotype

Author

Eussen, Simone R B M, Mank, Marko, Kottler, Robert, Hoffmann, Xenia-Katharina, Behne, Alexander, Rapp, Erdmann, Stahl, Bernd, Mearin, M Luisa, Koletzko, Berthold, Afd Pharmacology, Afd Chemical Biology and Drug Discovery, Pharmacology, Chemical Biology and Drug Discovery, Afd Pharmacology, Afd Chemical Biology and Drug Discovery, Pharmacology, and Chemical Biology and Drug Discovery

Subjects
Adult, 0301 basic medicine, HMOS, Group ii, human milk groups, lactation, Biology, galactosyllactoses, Article, 03 medical and health sciences, Animal science, oligosaccharides, Lactation, medicine, Humans, TX341-641, health care economics and organizations, Volume concentration, 030109 nutrition & dietetics, Nutrition and Dietetics, Milk, Human, Nutrition. Foods and food supply, Postpartum Period, human milk, Maternal Nutritional Physiological Phenomena, Phenotype, 030104 developmental biology, medicine.anatomical_structure, Female, Trisaccharides, Food Science
Abstract

Among the human milk oligosaccharides (HMOS), the galactosyllactoses (GLs) are only limitedly studied. This study aims to describe the presence and relative levels of HMOS, including GLs, in human milk (HM) according to maternal Secretor and Lewis (SeLe) phenotype and lactation stage. Relative levels of 19 HMOS were measured in 715 HM samples collected in the first 4 months postpartum from 371 donors participating in the PreventCD study. From a subset of 24 Dutch women (171 HM samples), samples were collected monthly up to 12 months postpartum and were additionally analyzed for relative and absolute levels of β6′-GL, β3′-GL and α3′-GL. Maternal SeLe phenotype or HM group was assigned based on the presence of specific fucosylated HMOS. Most HMOS, including β6′- and β3′-GL, were present in the vast majority (≥75%) of HM samples, whereas others (e.g., LNDFH II, 2′-F-LNH and α3′-GL) only occurred in a low number (&lt, 25%) of samples. Clear differences were observed between the presence and relative levels of the HMOS according to the maternal phenotype and lactation stage. Absolute concentrations of β6′-GL and β3′-GL were higher in HM group IV samples compared to samples of the other three HM groups. β3′-GL was also higher in HM group II samples compared to HM group I samples. β3′-GL and β6′-GL were stable over lactation stages. In conclusion, presence and levels of HMOS vary according to HM group and lactation stage. Not all HMOS behave similarly: some HMOS depend strongly on maternal phenotype and/or lactation stage, whereas others do not. β3′-GL and β6′-GL were present in low concentrations in over 75% of the analyzed HM samples and showed differences between HM groups, but not between the lactation stages.

Published
2021

43. Presence and Levels of Galactosyllactoses and Other Oligosaccharides in Human Milk and Their Variation during Lactation and According to Maternal Phenotype

Author

Afd Pharmacology, Afd Chemical Biology and Drug Discovery, Pharmacology, Chemical Biology and Drug Discovery, Eussen, Simone R B M, Mank, Marko, Kottler, Robert, Hoffmann, Xenia-Katharina, Behne, Alexander, Rapp, Erdmann, Stahl, Bernd, Mearin, M Luisa, Koletzko, Berthold, Afd Pharmacology, Afd Chemical Biology and Drug Discovery, Pharmacology, Chemical Biology and Drug Discovery, Eussen, Simone R B M, Mank, Marko, Kottler, Robert, Hoffmann, Xenia-Katharina, Behne, Alexander, Rapp, Erdmann, Stahl, Bernd, Mearin, M Luisa, and Koletzko, Berthold

Published
2021

44. Early diagnosis of coeliac disease in the Preventive Youth Health Care Centres in the Netherlands: study protocol of a case finding study (GLUTENSCREEN)

Author

Meijer-Boekel, Caroline, van den Akker-van Marle, M. Elske, Van Bodegom, L, Escher, Hankje, Van Geloven, Nan, van Overveld, Floris, Rings, Edmond, Smit, Lucy, de Vries, Martine C., Mearin, M. Luisa, Meijer-Boekel, Caroline, van den Akker-van Marle, M. Elske, Van Bodegom, L, Escher, Hankje, Van Geloven, Nan, van Overveld, Floris, Rings, Edmond, Smit, Lucy, de Vries, Martine C., and Mearin, M. Luisa

Abstract

Introduction Coeliac disease (CD) occurs in 1% of the population, develops early in life and is severely underdiagnosed. Undiagnosed and untreated disease is associated with short-term and long-term complications. The current healthcare approach is unable to solve the underdiagnosis of CD and timely diagnosis and treatment is only achieved by active case finding. Aim: to perform a case finding project to detect CD children who visit the Youth Health Care Centres (YHCCs) in a well-described region in the Netherlands to evaluate whether it is feasible, cost-effective and well accepted by the population. Methods/analysis Prospective intervention cohort study. Parents of all children aged 12 months and 4 years attending the YHCCs for a regular visit are asked whether their child has one or more CD-related symptoms from a standardised list. If so, they will be invited to participate in the case finding study. After informed consent, a point of care test (POCT) to assess CD-specific antibodies against tissue transglutaminase (TG2A) is performed onsite the YHCCs. If the POCT is positive, CD is highly suspected and the child will be referred to hospital for definitive diagnosis according to the Guideline Coeliac Disease of the European Society for Pediatric Gastroenterology, Hepatology and Nutrition guideline. Main outcomes Incidence rate of new CD diagnoses in the study region in comparison to the one in the same age diagnosed by standard of care in the rest of the Netherlands. Feasibility and cost-effectiveness of active CD case finding at the YHCCs. All costs of active case finding, diagnostics and treatment of CD and the potential short-term and long-term consequences of the disease will be calculated for the setting with and without case finding. Ethical acceptability: by questionnaires on parental and healthcare professionals' satisfaction. A statistical analysis plan was prepared and is published on the GLUTENSCREEN website (Statistical-Analysis-Plan-11-5-2021_def

Published
2021

48. Breast-Milk Microbiota Linked to Celiac Disease Development in Children: A Pilot Study From the PreventCD Cohort

Author

Benítez-Páez, Alfonso, primary, Olivares, Marta, additional, Szajewska, Hania, additional, Pieścik-Lech, Małgorzata, additional, Polanco, Isabel, additional, Castillejo, Gemma, additional, Nuñez, Merce, additional, Ribes-Koninckx, Carmen, additional, Korponay-Szabó, Ilma R., additional, Koletzko, Sibylle, additional, Meijer, Caroline R., additional, Mearin, M. Luisa, additional, and Sanz, Yolanda, additional

Published
2020
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49. Common and different genetic background for rheumatoid arthritis and coeliac disease

Author

Coenen, Marieke J.H., Trynka, Gosia, Heskamp, Sandra, Franke, Barbara, van Diemen, Cleo C., Smolonska, Joanna, van Leeuwen, Miek, Brouwer, Elisabeth, Boezen, Marike H., Postma, Dirkje S., Platteel, Mathieu, Zanen, Pieter, Lammers, Jan-Willem W.J., Groen, Harry J.M., Mali, Willem P.T.M., Mulder, Chris J., Tack, Greetje J., Verbeek, Wieke H.M., Wolters, Victorien M., Houwen, Roderick H.J., Mearin, M Luisa, van Heel, David A., Radstake, Timothy R.D.J., van Riel, Piet L.C.M., Wijmenga, Cisca, Barrera, Pilar, and Zhernakova, Alexandra

Published
2009

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