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1. The Alopecia Areata Severity and Morbidity Index (ASAMI) Study

Author

Group, ASAMI Consensus Survey Study, Moussa, Anthony, Bennett, Michaela, Wall, Dmitri, Meah, Nekma, York, Katherine, Bokhari, Laita, Asfour, Leila, Rees, Huw, Abraham, Leonardo Spagnol, Asz-Sigall, Daniel, Basmanav, Fitnat Buket, Bergfeld, Wilma, Betz, Regina C, Bhoyrul, Bevin, Blume-Peytavi, Ulrike, Callender, Valerie, Chitreddy, Vijaya, Combalia, Andrea, Cotsarelis, George, Craiglow, Brittany, Dhurat, Rachita, Donovan, Jeff, Doroshkevich, Andrei, Eisman, Samantha, Farrant, Paul, Ferrando, Juan, Gadzhigoroeva, Aida, Green, Jack, Grimalt, Ramon, Harries, Matthew, Hordinsky, Maria, Irvine, Alan, Jolliffe, Victoria, Kaiumov, Spartak, King, Brett, Lee, Joyce, Lee, Won-Soo, Li, Jane, Lortkipanidze, Nino, McMichael, Amy, Mesinkovska, Natasha Atanaskova, Messenger, Andrew, Mirmirani, Paradi, Olsen, Elise, Orlow, Seth J, Ovcharenko, Yuliya, Piraccini, Bianca Maria, Pirmez, Rodrigo, Rakowska, Adriana, Reygagne, Pascal, Rudnicka, Lidia, Corralo, David Saceda, Senna, Maryanne, Shapiro, Jerry, Sharma, Pooja, Siliuk, Tatiana, Starace, Michela, Suchonwanit, Poonkiat, Takwale, Anita, Tosti, Antonella, Vañó-Galván, Sergio, Visser, Willem I, Vogt, Annika, Wade, Martin, Yip, Leona, Zhou, Cheng, and Sinclair, Rodney

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Health Sciences, Autoimmune Disease, Good Health and Well Being, Humans, Alopecia Areata, Consensus, Quality of Life, Alopecia, Morbidity, ASAMI Consensus Survey Study Group, Oncology and Carcinogenesis
Abstract

ImportanceCurrent measures of alopecia areata (AA) severity, such as the Severity of Alopecia Tool score, do not adequately capture overall disease impact.ObjectiveTo explore factors associated with AA severity beyond scalp hair loss, and to support the development of the Alopecia Areata Severity and Morbidity Index (ASAMI).Evidence reviewA total of 74 hair and scalp disorder specialists from multiple continents were invited to participate in an eDelphi project consisting of 3 survey rounds. The first 2 sessions took place via a text-based web application following the Delphi study design. The final round took place virtually among participants via video conferencing software on April 30, 2022.FindingsOf all invited experts, 64 completed the first survey round (global representation: Africa [4.7%], Asia [9.4%], Australia [14.1%], Europe [43.8%], North America [23.4%], and South America [4.7%]; health care setting: public [20.3%], private [28.1%], and both [51.6%]). A total of 58 specialists completed the second round, and 42 participated in the final video conference meeting. Overall, consensus was achieved in 96 of 107 questions. Several factors, independent of the Severity of Alopecia Tool score, were identified as potentially worsening AA severity outcomes. These factors included a disease duration of 12 months or more, 3 or more relapses, inadequate response to topical or systemic treatments, rapid disease progression, difficulty in cosmetically concealing hair loss, facial hair involvement (eyebrows, eyelashes, and/or beard), nail involvement, impaired quality of life, and a history of anxiety, depression, or suicidal ideation due to or exacerbated by AA. Consensus was reached that the Alopecia Areata Investigator Global Assessment scale adequately classified the severity of scalp hair loss.Conclusions and relevanceThis eDelphi survey study, with consensus among global experts, identified various determinants of AA severity, encompassing not only scalp hair loss but also other outcomes. These findings are expected to facilitate the development of a multicomponent severity tool that endeavors to competently measure disease impact. The findings are also anticipated to aid in identifying candidates for current and emerging systemic treatments. Future research must incorporate the perspectives of patients and the public to assign weight to the domains recognized in this project as associated with AA severity.

Published
2024

3. Dermatology COVID-19 Registries: Updates and Future Directions

Author

Freeman, Esther E., Chamberlin, Grace C., McMahon, Devon E., Hruza, George J., Wall, Dmitri, Meah, Nekma, Sinclair, Rodney, Balogh, Esther A., Feldman, Steven R., Lowes, Michelle A., Marzano, Angelo V., Naik, Haley B., Castelo-Soccio, Leslie, Lara-Corrales, Irene, Cordoro, Kelly M., Mahil, Satveer K., Griffiths, Christopher E.M., Smith, Catherine H., Irvine, Alan D., Spuls, Phyllis I., Flohr, Carsten, and French, Lars E.

Published
2021
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4. The Alopecia Areata Consensus of Experts (ACE) study part II: Results of an international expert opinion on diagnosis and laboratory evaluation for alopecia areata

Author

Meah, Nekma, Wall, Dmitri, York, Katherine, Bhoyrul, Bevin, Bokhari, Laita, Asz-Sigall, Daniel, Bergfeld, Wilma F., Betz, Regina C., Blume-Peytavi, Ulrike, Callender, Valerie, Chitreddy, Vijaya, Combalia, Andrea, Cotsarelis, George, Craiglow, Brittany, Donovan, Jeff, Eisman, Samantha, Farrant, Paul, Green, Jack, Grimalt, Ramon, Harries, Matthew, Hordinsky, Maria, Irvine, Alan D., Itami, Satoshi, Jolliffe, Victoria, King, Brett, Lee, Won-Soo, McMichael, Amy, Messenger, Andrew, Mirmirani, Paradi, Olsen, Elise, Orlow, Seth J., Piraccini, Bianca Maria, Rakowska, Adriana, Reygagne, Pascal, Roberts, Janet L., Rudnicka, Lidia, Shapiro, Jerry, Sharma, Pooja, Tosti, Antonella, Vogt, Annika, Wade, Martin, Yip, Leona, Zlotogorski, Abraham, and Sinclair, Rodney D.

Published
2021
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8. The Alopecia Areata Severity and Morbidity Index (ASAMI) Study: Results From a Global Expert Consensus Exercise on Determinants of Alopecia Areata Severity.

Author

Moussa, Anthony, Bennett, Michaela, Wall, Dmitri, Meah, Nekma, York, Katherine, Bokhari, Laita, Asfour, Leila, Rees, Huw, Abraham, Leonardo Spagnol, Asz-Sigall, Daniel, Basmanav, Fitnat Buket, Bergfeld, Wilma, Betz, Regina C., Bhoyrul, Bevin, Blume-Peytavi, Ulrike, Callender, Valerie, Chitreddy, Vijaya, Combalia, Andrea, Cotsarelis, George, and Craiglow, Brittany

Published
2024
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10. Diffuse Lichen Planopilaris Masquerading as Diffuse Alopecia Areata.

Author

Yoo, Li Jie Helena, Meah, Nekma, Wall, Dmitri, and McDonald, Ian

Subjects
*LICHEN planus, *ALOPECIA areata, *BALDNESS, *SYMPTOMS, *DISEASE progression
Abstract

Introduction: Lichen planopilaris (LPP) is a primary lymphocytic cicatricial alopecia that represents a form of follicular lichen planus. Case Presentation: We describe a case of coexisting diffuse LPP and female pattern hair loss masquerading as diffuse alopecia areata in a 32-year-old female. Discussion: In complex cases such as this, dermoscopy-guided vertical and horizontal biopsies from androgen sensitive and insensitive areas are helpful in increasing diagnostic yield. Prompt initiation of treatment is key to halting disease progression. Long-term follow-up is important as resolution of clinical signs does not always correlate with the absence of disease progression. [ABSTRACT FROM AUTHOR]

Published
2024
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12. List of Contributors

Author

Abdullah, Anthony, primary, Abrouk, Michael, additional, Ahad, Tashmeeta, additional, Ahmed, Imtiaz, additional, Al Hammadi, Anwar, additional, Allen, Caroline, additional, Almohssen, Amer Ali, additional, Alwan, Wisam, additional, Ameen, Mahreen, additional, Amini, Sadegh, additional, Anderson, Bryan E., additional, Anhalt, Grant J., additional, Baker, Donald J., additional, Bala, Harini Rajgopal, additional, Baltz, Julia, additional, Banach, David, additional, Banfield, Cedric C., additional, Baran, Robert, additional, Bardhan, Ajoy, additional, Barkham, Melissa C., additional, Bello, Ysabel M., additional, Benton, Emma, additional, Bergfeld, Wilma F., additional, Berkowitz, Eric, additional, Berman, Brian, additional, Bernhard, Jeffrey D., additional, Bernstein, Daniel, additional, Berth-Jones, John, additional, Bhate, Chinmoy, additional, Bhatia, Bhavnit K., additional, Blume, Jonathan E., additional, Bordet, Nevianna, additional, Borysiewicz, Catherine, additional, Brauner, Gary J., additional, Brodell, Robert T., additional, Brown, Marc D., additional, Burd, Robert M., additional, Burdick, Anne E., additional, Butala, Niraj, additional, Callen, Jeffrey P., additional, Camacho, Ivan D., additional, Camasmie, Helena, additional, Caplivski, Daniel, additional, Cappell, Mitchell S., additional, Casey, Genevieve A., additional, Chan, Lawrence S., additional, Chan, Loi-Yuen, additional, Chen, Jennifer K., additional, Chen, Chen “Mary”, additional, Chiang, Nicole Yi Zhen, additional, Chiaravalloti, Anthony J., additional, Child, Fiona J., additional, Chu, Anthony C., additional, Clayton, Timothy H., additional, Cohen, Steven R., additional, Cooper, Elizabeth A., additional, Cooper, Susan M., additional, Collier, Nick, additional, Correnti, Christina M., additional, Coulson, Ian H., additional, Council, M. Laurin, additional, Cowper, Shawn E., additional, Craven, Nicholas M., additional, Creamer, Daniel, additional, Cruz, Ponciano D., additional, Cusack, Carrie Ann R., additional, Daunton, Adam, additional, Davis, Mark D.P., additional, Dawe, Robert S., additional, D’Cruz, David P., additional, de Berker, David, additional, DeHoratius, Danielle M., additional, Deng, Min, additional, Desai, Seemal R., additional, Devlin, Georgina, additional, DiGiovanna, John J., additional, Doctoroff, Alexander, additional, Dodiuk-Gad, Roni P., additional, Eichenfield, Dawn Z., additional, Eichenfield, Lawrence F., additional, Eisen, Drore, additional, Eke, Ure, additional, Elston, Dirk M., additional, Emanuel, Patrick O.M., additional, Enos, Clinton W., additional, Ensanyat, Shaheen H., additional, Falabella, Anna F., additional, Farberg, Aaron S., additional, Feigenbaum, Lawrence S., additional, Fernandez, Kristen Heins, additional, Fett, Nicole, additional, Finlay, Andrew Y., additional, Firoz, Bahar F., additional, Firoz, Elnaz F., additional, Fitzpatrick, James E., additional, Flischel, Amy E., additional, Foley, Kelly A., additional, Freedman, Derek, additional, Fremlin, Georgina A., additional, Fried, Richard, additional, Friedlander, Philip, additional, Friedman, Adam, additional, Forrestel, Amy K., additional, Fuchs, Brian S., additional, Gach, Joanna E., additional, Galan, Anjela, additional, Ganesh, Jaya, additional, Garg, Amit, additional, Geller, Lauren, additional, Gelmetti, Carlo M., additional, Ghazi, Elizabeth, additional, Ghunawat, Sneha, additional, Goldberg, Leonard H., additional, Goodfield, Mark J.D., additional, Gordon, Marsha L., additional, Gowda, Asha, additional, Grabell, Daniel A., additional, Grant, Matthew, additional, Grattan, Clive E.H., additional, Greaves, Malcolm W., additional, Green, Justin J., additional, Griffiths, Christopher E.M., additional, Gropper, Charles A., additional, Grossberg, Anna L., additional, Gupta, Aditya K., additional, Hadi, Ali S., additional, Hadi, Suhail M., additional, Hagans, Iris A., additional, Hairston, Bethany R., additional, Halpern, Analisa Vincent, additional, Halverstam, Caroline, additional, Harper, Natasha, additional, Harries, Matthew J., additional, Harris, John, additional, Harrison, Shannon, additional, Hatch, Michael M., additional, Heagerty, Adrian H.M., additional, Hebert, Adelaide A., additional, Helms, Stephen E., additional, Hexsel, Camile L., additional, Hexsel, Doris M., additional, Heymann, Warren R., additional, Higgins, Elisabeth M., additional, Higgins, Claire L., additional, High, Whitney A., additional, Hönigsmann, Herbert, additional, Horenstein, Marcelo G., additional, Hruza, George J., additional, Hui, Andrea, additional, Huo, Ran, additional, Ibbotson, Sally H., additional, Ibrahim, Sherrif F., additional, Ilchyshyn, Andrew, additional, Ismail, Dina, additional, Jablonska, Stefania, additional, Jacobe, Heidi T., additional, James, William D., additional, Javed, Aysha, additional, Jemec, Gregor B.E., additional, Johnston, Graham A., additional, Jones, Stephen K., additional, Junkins-Hopkins, Jacqueline M., additional, Kaffenberger, Jessica, additional, Kane, Kelly R., additional, Kanelleas, Antonios, additional, Karadağ, Ayşe Serap, additional, Karas, Laura, additional, Katugampola, Ruwani P., additional, Katz, Bruce E., additional, Kellen, Roselyn, additional, Khan, Murtaza, additional, Khorasani, Hooman, additional, Kim, Ellen J., additional, Kim, Hee J., additional, Kirby, Brian, additional, Kirby, Joslyn S., additional, Klein, Rachel S., additional, Kleydman, Kate, additional, Koch, Dimitra, additional, Kohorst, John J., additional, Koo, John Y.M., additional, Kopp, Sandra A., additional, Korman, Neil J., additional, Kovarik, Carrie, additional, Kraemer, Kenneth H., additional, Krafchik, Bernice R., additional, Krishnamurthy, Karthik, additional, Kvernebo, Knut, additional, Lam, Charlene, additional, Lambert, Peter C., additional, Langtry, James A.A., additional, Larian, Amir A., additional, Larocca, Cecilia A., additional, Lawlor, E. Frances, additional, Lawrence, Clifford M., additional, Lebwohl, Mark G., additional, Lebwohl, Oscar, additional, Lehman, Julia S., additional, Leslie, Tabi A., additional, Lessin, Stuart R., additional, Levitt, Jacob O., additional, Lewis, Fiona M., additional, Liaqat, Maryam, additional, Liu, Kristina J., additional, Loosemore, Michael P., additional, Luger, Thomas A., additional, Lupi, Omar, additional, Lushniak, Boris D., additional, Lyon, Calum C., additional, Maderal, Andrea D., additional, Mahmoud, Bassel H., additional, Majewski, Slawomir, additional, Mallett, Richard B., additional, Manders, Steven M., additional, Mann, Ranon, additional, Mansouri, Yasaman, additional, Margolis, David J., additional, Markowitz, Orit, additional, Marsland, Alexander, additional, Martin-Clavijo, Agustin, additional, Martinez, Daniela, additional, Matiz, Catalina, additional, Maurer, Marcus, additional, McKerrow, Kevin, additional, Meah, Nekma, additional, Micali, Giuseppe, additional, Micheletti, Robert G., additional, Millard, Leslie G., additional, Miller, James E., additional, Wong Millsop, Jillian W., additional, Mimouni, Daniel, additional, Mirowski, Ginat W., additional, Mirza, Sultan A., additional, Molin, Sonja, additional, Morales-Burgos, Adisbeth, additional, Morison, Warwick L., additional, Mørk, Cato, additional, Morton, Colin A., additional, Motley, Richard J., additional, Mowbray, Megan, additional, Muldoon, Eavan G., additional, Muncaster, Anna E., additional, Murakawa, George J., additional, Murase, Jenny E., additional, Murdoch, Michele E., additional, Nabatian, Adam S., additional, Nakamura, Mio, additional, Nalluri, Rajani, additional, Nawas, Zeena Y., additional, Needham, Glen R., additional, Newell, Glenn C., additional, Newton-Bishop, Julia, additional, Nguyen, Adam V., additional, Nixon, Rosemary L., additional, O’Brien, Jack C., additional, Ogden, Stephanie, additional, Olbricht, Suzanne M., additional, O’Shea, Sally Jane, additional, Owen, Cindy E., additional, Pan, Michael, additional, Pappas-Taffer, Lisa, additional, Parish, Jennifer L., additional, Parish, Lawrence Charles, additional, Payette, Michael, additional, Peck, Gary L., additional, Pena, Sandra, additional, Peranteau, Jarad, additional, Pereira, Frederick A., additional, Perkins, William, additional, Perlis, Clifford S., additional, Phelps, Robert G., additional, Phillips, Tania J., additional, Poh-Fitzpatrick, Maureen B., additional, Pomeranz, Miriam Keltz, additional, Pop, Samantha R., additional, Porcu, Pierluigi, additional, Powell, James B., additional, Prok, Lori D., additional, Pyle, Tia M., additional, Qazaz, Surod, additional, Rajkomar, Vikram, additional, Rashid, Rabia S., additional, Rashighi, Mehdi, additional, Ratnavel, Ravi, additional, Regula, Christie G., additional, Renzi, Michael, additional, Revuz, Jean, additional, Reynolds, Rachel V., additional, Richard, Elisabeth, additional, Richard, Gabriele, additional, Rigel, Darrell S., additional, Robles, Wanda Sonia, additional, Rogge, Megan, additional, Rook, Alain H., additional, Manning, Jamie R., additional, Rosen, Ted, additional, Rosenbach, Misha, additional, Rosenfeld, David, additional, Rowland Payne, Christopher, additional, Rubin, Adam I., additional, Rubin, Courtney, additional, Rustin, Malcolm H.A., additional, Ruzicka, Thomas, additional, Samimi, Sara, additional, Schachner, Lawrence A., additional, Scheinfeld, Noah, additional, Schlosser, Bethanee J., additional, Schnur, Rhonda E., additional, Schwartz, Robert A., additional, Scorer, Matthew J., additional, Selkin, Bryan A., additional, Seymour, Jamie, additional, Shaver, Christine M., additional, Shea, Christopher R., additional, Shear, Neil H., additional, Shim, Tang Ngee, additional, Shimizu, Hiroshi, additional, Siegel, Julia, additional, Singer, Elisha, additional, Skelsey, Maral Kibarian, additional, Sladden, Chris, additional, Sladden, Michael, additional, Smith, Janellen, additional, Smucker, Joanne E., additional, Somani, Najwa, additional, Sommer, Lacy L., additional, Sommerlad, Mary, additional, Soon, Christine, additional, Sopkovich, Jennifer A., additional, Soter, Nicholas A., additional, Spencer, James M., additional, Staughton, Richard C.D., additional, Sterling, Jane C., additional, Sunderkötter, Cord, additional, Taibjee, Saleem M., additional, Tamura, Deborah, additional, Tan, Eunice, additional, Tang, William Y-M., additional, Taylor, Lynsey, additional, Thiers, Bruce H., additional, Thomas, Lucy J., additional, Thornton, Cody R., additional, Tobin, Anne-Marie, additional, Torgerson, Rochelle R., additional, Tosti, Antonella, additional, Tsatsou, Fragkiski, additional, Tsuji-Abe, Yukiko, additional, Tucker, William F.G., additional, Tyring, Stephen K., additional, Udkoff, Jeremy, additional, Unger, Robin H., additional, Unger, Walter P., additional, Utz, Sarah, additional, Valbuena, Martha C., additional, van de Kerkhof, Peter, additional, Van Voorhees, Abby S., additional, Vangipuram, Ramya, additional, Veitch, David, additional, Venning, Vanessa, additional, Versteeg, Sarah G., additional, Viera, Martha, additional, Vittorio, Carmela C., additional, Vleugels, Ruth Ann, additional, Wali, Gorav N., additional, Wallengren, Joanna, additional, Wan, Joy, additional, Wanat, Karolyn A., additional, Weichert, Gabriele, additional, Weidmann, Anja K., additional, Weinberg, Jeffrey M., additional, Werth, Victoria P., additional, White, Lucile E., additional, Wiener, Adam H., additional, Wilkin, Jonathan K., additional, Wilkin, Nathaniel K., additional, Williams, Jason, additional, Wilson, Niall, additional, Wiss, Karen, additional, Witkowski, Joseph A., additional, Wiznia, Lauren E., additional, Wong, Henry K., additional, Wong, Junie Li Chun, additional, Wright, Andrew L., additional, Wriston, Cooper C., additional, Wu, Benedict C., additional, Wulkan, Adam, additional, Zaenglein, Andrea L., additional, Zaki, Irshad, additional, Zeichner, Joshua A., additional, Zhu, Tian Hao, additional, Zone, John J., additional, Zouboulis, Christos C., additional, and Zuberbeir, Torstein, additional

Published
2018
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26. Advances in hair growth

Author

Wall, Dmitri, primary, Meah, Nekma, additional, Fagan, Nicole, additional, York, Katherine, additional, and Sinclair, Rodney, additional

Published
2022
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28. Learning from disease registries during a pandemic: Moving toward an international federation of patient registries

Author

Wall, Dmitri, primary, Alhusayen, Raed, additional, Arents, Bernd, additional, Apfelbacher, Christian, additional, Balogh, Esther A., additional, Bokhari, Laita, additional, Bloem, Manja, additional, Bosma, Angela L., additional, Burton, Tim, additional, Castelo-Soccio, Leslie, additional, Fagan, Nicole, additional, Feldman, Steven R., additional, Fletcher, Godfrey, additional, Flohr, Carsten, additional, Freeman, Esther, additional, French, Lars E., additional, Griffiths, Christopher E.M., additional, Hruza, George J., additional, Ingram, John R., additional, Kappelman, Michael D., additional, Lara-Corrales, Irene, additional, Lim, Henry W., additional, Meah, Nekma, additional, McMahon, Devon E., additional, Mahil, Satveer K., additional, McNicoll, Ian, additional, Musters, Annelie, additional, Naik, Haley B., additional, Sinclair, Rodney, additional, Smith, Catherine H., additional, Spuls, Phyllis, additional, Tobin, Desmond J., additional, York, Katherine, additional, and Irvine, Alan D., additional

Published
2021
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29. A Global eDelphi Exercise to Identify Core Domains and Domain Items for the Development of a Global Registry of Alopecia Areata Disease Severity and Treatment Safety (GRASS)

Author

Wall, Dmitri, primary, Meah, Nekma, additional, York, Katherine, additional, Bhoyrul, Bevin, additional, Bokhari, Laita, additional, Abraham, Leonardo Spagnol, additional, Adams, Roisín, additional, Bergfeld, Wilma, additional, Betz, Regina C., additional, Blume-Peytavi, Ulrike, additional, Callender, Valerie, additional, Campbell, Chel, additional, Chambers, Jen, additional, Chen, Gang, additional, Chitreddy, Vijaya, additional, Cotsarelis, George, additional, Craiglow, Brittany, additional, Dhurat, Rachita, additional, Dlova, Ncoza, additional, Donovan, Jeff, additional, Duque-Estrada, Bruna, additional, Eisman, Samantha, additional, Ellison, Abby, additional, Farrant, Paul, additional, Barberá, Juan Ferrando, additional, Gadzhigoroeva, Aida, additional, Grimalt, Ramon, additional, Harries, Matthew, additional, Hordinsky, Maria, additional, Irvine, Alan D., additional, Jolliffe, Victoria, additional, Jones, Leslie, additional, King, Brett, additional, Lee, Won-Soo, additional, Lortkipanidze, Nino, additional, McMichael, Amy, additional, Messenger, Andrew, additional, Mirmirani, Paradi, additional, Olsen, Elise, additional, Orlow, Seth J., additional, Ovcharenko, Yuliya, additional, Piraccini, Bianca Maria, additional, Pirmez, Rodrigo, additional, Rakowska, Adriana, additional, Reygagne, Pascal, additional, Riley, Melissa, additional, Rudnicka, Lidia, additional, Saceda Corralo, David, additional, Shapiro, Jerry, additional, Sharma, Pooja, additional, Silyuk, Tatiana, additional, Kaiumov, Spartak, additional, Tobin, Desmond J., additional, Tosti, Antonella, additional, Vañó-Galván, Sergio, additional, Vogt, Annika, additional, Wade, Martin, additional, Yip, Leona, additional, Zlotogorski, Abraham, additional, Zhou, Cheng, additional, and Sinclair, Rodney, additional

Published
2021
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36. International collaboration and rapid harmonization across dermatologic COVID-19 registries

Author

Freeman, Esther E., primary, McMahon, Devon E., additional, Hruza, George J., additional, Irvine, Alan D., additional, Spuls, Phyllis I., additional, Smith, Catherine H., additional, Mahil, Satveer K., additional, Castelo-Soccio, Leslie, additional, Cordoro, Kelly M., additional, Lara-Corrales, Irene, additional, Naik, Haley B., additional, Alhusayen, Raed, additional, Ingram, John R., additional, Feldman, Steven R., additional, Balogh, Esther A., additional, Kappelman, Michael D., additional, Wall, Dmitri, additional, Meah, Nekma, additional, Sinclair, Rodney, additional, Beylot-Barry, Marie, additional, Fitzgerald, Matthew, additional, French, Lars E., additional, Lim, Henry W., additional, Griffiths, Christopher E.M., additional, and Flohr, Carsten, additional

Published
2020
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40. The Alopecia Areata Consensus of Experts (ACE) study: Results of an international expert opinion on treatments for alopecia areata

Author

Meah, Nekma, primary, Wall, Dmitri, additional, York, Katherine, additional, Bhoyrul, Bevin, additional, Bokhari, Laita, additional, Sigall, Daniel Asz, additional, Bergfeld, Wilma F., additional, Betz, Regina C., additional, Blume-Peytavi, Ulrike, additional, Callender, Valerie, additional, Chitreddy, Vijaya, additional, Combalia, Andrea, additional, Cotsarelis, George, additional, Craiglow, Brittany, additional, Donovan, Jeff, additional, Eisman, Samantha, additional, Farrant, Paul, additional, Green, Jack, additional, Grimalt, Ramon, additional, Harries, Matthew, additional, Hordinsky, Maria, additional, Irvine, Alan D., additional, Itami, Satoshi, additional, Jolliffe, Victoria, additional, King, Brett, additional, Lee, Won-Soo, additional, McMichael, Amy, additional, Messenger, Andrew, additional, Mirmirani, Paradi, additional, Olsen, Elise, additional, Orlow, Seth J., additional, Piraccini, Bianca Maria, additional, Rakowska, Adriana, additional, Reygagne, Pascal, additional, Roberts, Janet L., additional, Rudnicka, Lidia, additional, Shapiro, Jerry, additional, Sharma, Pooja, additional, Tosti, Antonella, additional, Vogt, Annika, additional, Wade, Martin, additional, Yip, Leona, additional, Zlotogorski, Abraham, additional, and Sinclair, Rodney, additional

Published
2020
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45. List of Contributors

Author

Abdullah, Anthony, Abel, Mary Kathryn, Abudu, Boya, Abu-Hilal, Mohannad, Al Hammadi, Anwar, Al Awadhi, Ameen, Alexis, Andrew F., Aljefri, Khadija, Al-Kutubi, Huda, Almazan, Timothy H., Almohssen, Amer Ali, Alpsoy, Erkan, Ameen, Mahreen, Anderson, Bryan E., Anshelevich, Ellen, Bacik, Lindsay C., Baker, Donald J., Banach, David, Banfield, Cedric C., Baran, Robert, Barankin, Benjamin, Barkham, Melissa C., Bauer, Johann W., Begun, Zoe, Bell, Michael A., Benton, Emma, Bergfeld, Wilma F., Berman, Brian, Berth-Jones, John, Bhate, Chinmoy, Bhatia, Bhavnit K., Bilgiç, Asli, Bitterman, Avi, Black, Samantha, Blume, Jonathan E., Bohelay, Gérôme, Bordet, Nevianna, Brodell, Robert T., Brown, Marc D., Brownstone, Nicholas D., Burdick, Anne E., Butala, Niraj, Callen, Jeffrey P., Camacho, Ivan D., Camasmie, Helena, Caplivski, Daniel, Cappell, Mitchell S., Casey, Genevieve A., Caux, Frédéric, Chan, Cynthia X., Chan, Lawrence S., Chan, Loi-Yuen, Chan, Stephanie, Chao, Kevin Young, Chen, Jennifer K., Child, Fiona J., Choate, Keith, Chosidow, Olivier, Chousakos, Emmanouil, Chuh, Antonio A.T., Cices, Ahuva, Cobos, Gabriela A., Cohen, Steven R., Collier, Nicholas, Cooper, Elizabeth A., Coulson, Ian H., Cowen, Edward W., Craiglow, Brittany, Cruz, Ponciano D., Jr., Cummins, Donna, Cusack, Carrie Ann R., Daniel, Benjamin S., Daunton, Adam R.A., Davis, Mark D.P., Dawe, Robert S., D’Cruz, David P., de Berker, David, de Brito, Marianne, De Maeseneer, Hannelore, de Moll, Ellen H., Decker, Ashley, DeHoratius, Danielle M., Del Rosso, James Q., Desai, Seemal R., Dhawan, Gaurav K., DiGiovanna, John J., Dodiuk-Gad, Roni P., Duffy, Robert F., Dummer, Reinhard, Dunn, Annie, Duong, Tu-Anh, Dutz, Jan P., Eichenfield, Dawn Z., Eichenfield, Lawrence F., Eisen, Drore, Elman, Scott A., Elston, Dirk M., Elyoussfi, Sarah, Emanuel, Patrick O.M., Enos, Clinton W., Noliza Encarnacion, Maria Rosa, Epstein, Ervin H., Jr., Farberg, Aaron S., Farrugia, Michael E., Fassihi, Hiva, Fawaz, Bilal, Feigenbaum, Lawrence S., Felmingham, Claire, Femia, Alisa, Fenner, Justine, Ferguson, Felicity, Fett, Nicole, Finlay, Andrew Y., Firooz, Alireza, Firoz, Bahar F., Flischel, Amy E., Forrestel, Amy, Foley, Kelly A., Fourzali, Kayla, Frare, Cindy P., Freedman, Derek, Frey, Surina, Fried, Richard, Friedman, Adam J., Fuller, L. Claire, Gabel, Colleen, Gach, Joanna E., Ganesh, Jaya, Ganjoo, Shikhar, Gao, Jing Mia, Gaspari, Anthony A., Glaser, Katherine, Goenaga-Vázquez, Yamila, Goldberg, Leonard H., Goldfarb, Johanna, González Barreto, Reina M., Goon, Peter K.C., Gottlieb, Alice B., Gowda, Asha, Grada, Ayman A., Grande, Donald J., Grant, Matthew, Grattan, Clive E.H., Green, Justin J., Grimes, Pearl E., Gropper, Charles A., Grossberg, Anna L., Gupta, Aditya K., Guttman-Yassky, Emma, Guzman, Anthony K., Haddadi, Nazgol-Sadat, Hadi, Ali S., Hadi, Suhail M., Hagans, Iris A., Hairston, Bethany R., Halpern, Analisa Vincent, Halverstam, Caroline, Haque, Emily, Harries, Matthew, Harris, John E., Haw, William, Hazan, Ezra, Heaton, Henry, Hebert, Adelaide A., Helm, Matthew F., Helms, Stephen E., Hexsel, Camille L., Hexsel, Doris M., Heymann, Warren R., High, Whitney A., Hoffman, Melissa, Horenstein, Marcelo G., Hurst, Eva A., Hussain, Walayat, Ibbotson, Sally H., Ibrahim, Sherrif F., Inamadar, Arun C., Ingen-Housz-Oro, Saskia, Iorizzo, Matilde, Jacobe, Heidi, James, William D., Jemec, Gregor B.E., Jennings, Tara, Jibbe, Atieh S., Johnston, Graham A., Joly, Pascal, Joseph, Adrienne, Kanelleas, Antonios, Karadağ, Ayşe Serap, Katugampola, Ruwani P., Katz, Bruce E., Kavanagh, Gina M., Khan, Sidra S., Khattri, Saakshi, Khong, Brendan, Khorasani, Hooman, Kim, Ellen J., Kim, Hee J., Kim, Youn H., King, Brett, Kirby, Joslyn S., Kirby, Lisa, Kirsner, Robert S., Ko, Lauren, Koch, Dimitra, Koh, Wei-Liang, Koo, John Y.M., Kopp, Sandra A., Kouby, Floriane, Kovarik, Carrie, Kraemer, Kenneth H., Kreeshan, Firas C., Krishnamurthy, Karthik, Kroshinsky, Daniela, Krueger, Steven, Kvernebo, Knut, Laimer, Martin, Lalor, Leah, Lam, Charlene, Lambert, Peter C., Lang, Claudia, Lawlor, Frances, Lawrence, Naomi, Layher, Heather, Lebwohl, Mark G., Lebwohl, Oscar, Lee, Helen, Lehman, Julia S., Lemieux, Alexandre, Leslie, Tabi A., Leung, Alexander K.C., Levitt, Jacob O., Lewis, Daniel J., Lewis, Fiona M., Liaqat, Maryam, Ling, Tsui Chin, Litchman, Graham H., Liu, Stephanie, Luger, Thomas A., Luna, Paula C., Lupi, Omar, Lyon, Calum C., Maatouk, Ismael, MacGibeny, Margaret A., Maddukuri, Spandana, Mahmoud, Bassel H., Makkar, Timothy, Mallett, Richard B., Malta, Kiana, Manci, Rachel, Mancuso, Jennifer, Manders, Steven, Mann, Jasmine, Marghoob, Ashfaq A., Markova, Alina, Markowitz, Orit, Martinez, Daniela, Martinka, Michal, Maurer, Marcus, McGee, Jean S., McLarney, R. Matthew, Meah, Nekma, Metz, Martin, Micali, Giuseppe, Michalik, Daniel, Micheletti, Robert G., Mirowski, Ginat W., Mori, Shoko, Mørk, Cato, Morris, Caroline R., Morton, Colin A., Motaparthi, Kiran, Muldoon, Eavan G., Murase, Jenny E., Murdoch, Michele E., Murrell, Dedee F., Muthiah, Shareen, Myers, Bridget, Naeem, Zunaira, Nakamura, Mio, Nambi, Rabindranath, Nasca, Maria R., Navarrete-Dechent, Cristian, Needham, Glen R., Nehal, Kishwer, Newell, Glenn C., Nixon, Rosemary L., Noy, Mariana L., Nunns, David, Olbricht, Suzanne M., Oldenburg, Reid, Orekoya, Fikki, Osborne, Ruth A., Owen, Cindy E., Pandya, Amit G., Papaefthymiou, Vasileios, Paravar, Taraneh, Parish, Jennifer L., Parish, Lawrence Charles, Perz, Allison M., Peterson, Danielle, Phelps, Robert G., Philips, Rebecca C., Phillips, Tania J., Poh-Fitzpatrick, Maureen B., Polansky, Maxim, Pomeranz, Miriam Keltz, Pope, Elena, Privalle, Ashley N., Prost, Catherine, Que, Syril Keena T., Quint, Koen, Qureshi, Sumera, Rashid, Rabia S., Rashighi, Mehdi, Ratnavel, Ravi, Rawi, Sarah, Reddy, Vidhatha, Renzi, Michael A., Jr., Revuz, Jean, Richard, Gabriele, Rigel, Darrell S., Rivera, Sydney, Robles, Wanda S., Rodriguez, Ramiro, Jr., Rook, Alain H., Rosen, Ted, Rosenbach, Misha, Rowland, Emma, Rustin, Malcolm, Sadlier, Muriel, Salavastru, Carmen Maria, Samimi, Sara, Sandoval, Erika Romero, Sarkany, Robert P.E., Scerri, Lawrence, Schimmel, Joshua, Schmults, Chrysalyne D., Schnur, Rhonda E., Schoinas, Spyridon, Schwartz, Robert A., Scorer, Matthew J., Shah, Kalee, Shah, Nidhi, Shah, Radhika, Shah, Sheevam, Sharif, Jennifer, Shea, Christopher R., Shear, Neil H., Sheriff, Tabrez, Shields, Bridget E., Shimizu, Hiroshi, Shinkai, Kanade, Shiu, Jessica, Shivanna, Ragunatha, Shwayder, Tor, Silverberg, Nanette, Sinclair, Rodney, Singal, Archana, Smith, Janellen, Snyder, Margaret L., Sommer, Lacy L., Soter, Nicholas A., Stanger, Roselyn K., Stoll, Joseph R., Sun, Qisi, Sunderkötter, Cord, Swali, Ritu, Taibjee, Saleem M., Talasila, Sreya, Talebi-Liasi, Faezeh, Tamura, Deborah, Tan, Eunice, Y.-M. Tang, William, Thibodeaux, Quinn, Tian, Tina M., Tiplica, George Sorin, Tkachenko, Elizabeth, Tolkachjov, Stanislav N., Tolliver, Starling D., Tomecki, Kenneth, Torgerson, Rochelle R., Tosti, Antonella, Tsuji-Abe, Yukiko, Twaij, Sara, Tyring, Stephen K., van de Kerkhof, Peter, Van Gysel, Dirk, Van Voorhees, Abby S., Varma, Aakaash, Vasani, Resham, Verma, Shyam B., Vermeer, Maarten H., Vieira, Carlos, Vignes, Stéphane, Vleugels, Ruth Ann, Wallengren, Joanna, Wanat, Karolyn A., Wang, Erica B., Wei, Chapman, Weichert, Gabriele, Weigelt, Maximillian A., Weinberg, Jeffrey M., Weitzer, Danielle, Welponer, Tobias, Werth, Victoria P., White, Lucile E., Wilkin, Jonathan K., Wilson, Niall, Wiznia, Lauren E., Wollenberg, Andreas, Wollina, Uwe, Chun Wong, Junie Li, Wright, Andrew L., Wynne, Matthew, Yan, Daisy, Yosipovitch, Gil, Youssef, Molly J., Zaenglein, Andrea L., Zaki, Irshad, Zarbo, Allison, Zawar, Vijay, Zhu, Jane L., Zone, John J., and Zuberbier, Torsten

Published
2022
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46. Treatment of alopecia areata: An Australian expert consensus statement

Author

Cranwell, William C, primary, Lai, Vivien WY, additional, Photiou, Louise, additional, Meah, Nekma, additional, Wall, Dmitri, additional, Rathnayake, Deepani, additional, Joseph, Shobha, additional, Chitreddy, Vijaya, additional, Gunatheesan, Shyamalar, additional, Sindhu, Kamaldeep, additional, Sharma, Pooja, additional, Green, Jack, additional, Eisman, Samantha, additional, Yip, Leona, additional, Jones, Leslie, additional, and Sinclair, Rodney, additional

Published
2018
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47. Treatment of alopecia areata in pre‐adolescent children with oral tofacitinib: A retrospective study.

Author

Jerjen, Rebekka, Meah, Nekma, Trindade de Carvalho, Lara, Wall, Dmitri, Eisman, Samantha, and Sinclair, Rodney

Subjects
*ALOPECIA areata, *AGE of onset, *BALDNESS, *PATIENTS' attitudes, *ORAL medication, *RETROSPECTIVE studies
Abstract

Background: Alopecia areata (AA) is an autoimmune hair loss condition that affects people of all ages. Early age of onset and prolonged disease duration indicate poor prognosis. Janus kinase inhibitors are being investigated in phase 3 clinical trials in adolescents and adults with AA Objective: To evaluate the use of oral tofacitinib in pre‐adolescent patients with AA. Methods: A retrospective review of case records of all pre‐adolescent patients with AA treated with oral tofacitinib in a single center between 2018 and 2019. Results: Fourteen patients were identified, aged 7 to 11 years. Nine patients experienced clinically significant improvement in their SALT (Severity of Alopecia Tool) score. Three patients achieved complete remission (SALT score of 0), seven (63.6%) achieved over 50% improvement in SALT score from baseline. One patient had no change from baseline, another experienced additional hair loss. After an average of 9 months of treatment, the median SALT score improvement was 67.7%. The improvement was similar in patients with baseline SALT scores greater than 50 and those with baseline SALT scores below 10. Adverse events were mild. Limitations: The retrospective nature of the data, small sample size, lack of a control group, referral bias to a specialist hair center, and concomitant use of other medications including oral minoxidil in all patients. Conclusion: There is a role for tofacitinib as a systemic therapy in AA and this should be further evaluated in prospective clinical trials in pre‐adolescents. [ABSTRACT FROM AUTHOR]

Published
2021
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48. Cross-specialty identification of the JAK1 inhibitor trial agent filgotinib as a potential therapy for alopecia areata.

Author

Fagan, Nicole, Doherty, Glen A, Meah, Nekma, Sinclair, Rodney, and Wall, Dmitri

Subjects
ALOPECIA areata, CYTOTOXIC T cells, JAK-STAT pathway, KILLER cells, THERAPEUTICS, INDIVIDUALIZED medicine
Abstract

Https://doi.org/10.1093/bjd/ljac103 Dear Editor, Alopecia areata (AA) ranks among the most common autoimmune conditions in humans, with an approximate lifetime risk of 0.7-4%.[1] It classically presents with patchy, nonscarring hair loss that can have a profound adverse psychosocial effect. While multiple JAKi are in development to treat AA, this case is a reminder of the need to consider other diseases where JAKi are utilized, to unearth potential therapies and identify the optimal therapy for patients with multiple autoimmune diseases, which patients with AA are at increased risk of developing. A global eDelphi exercise to identify core domains and domain items for the development of a Global Registry of Alopecia Areata Disease Severity and Treatment Safety (GRASS). [Extracted from the article]

Published
2023
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49. Treatment of alopecia areata: An Australian expert consensus statement.

Author

Cranwell, William C, Lai, Vivien WY, Photiou, Louise, Meah, Nekma, Wall, Dmitri, Rathnayake, Deepani, Joseph, Shobha, Chitreddy, Vijaya, Gunatheesan, Shyamalar, Sindhu, Kamaldeep, Sharma, Pooja, Green, Jack, Eisman, Samantha, Yip, Leona, Jones, Leslie, and Sinclair, Rodney

Subjects
ALOPECIA areata, THERAPEUTICS, BALDNESS, PSYCHOLOGICAL distress, MYCOPHENOLIC acid, CLINICAL indications
Abstract

Alopecia areata (AA) severity varies from a single small patch to complete loss of scalp hair, body hair, eyelashes and eyebrows. While 40% of all affected individuals only ever get one patch and will achieve a spontaneous complete durable remission within 6 months, 27% will develop additional patches but still achieve complete durable remission within 12 months and 33% will develop chronic AA. Without systemic treatment, 55% of individuals with chronic AA will have persistent multifocal relapsing and remitting disease, 30% will ultimately develop alopecia totalis and 15% will develop alopecia universalis. The unpredictable course and psychological distress attributable to AA contributes to the illness associated with AA. Numerous topical, intralesional and systemic agents are currently used to treat AA; however, there is a paucity of data evaluating their use, effectiveness and tolerability. Topical therapy, including topical glucocorticosteroids, minoxidil and immunotherapy, can be used in cases of limited disease. There are no universally agreed indications for initiating systemic treatment for AA. Possible indications for systemic treatment include rapid hair loss, extensive disease (≥50% hair loss), chronic disease, severe distress or a combination of these factors. Currently available systemic treatments include glucocorticosteroids, methotrexate, ciclosporin, azathioprine, dapsone, mycophenolate mofetil, tacrolimus and sulfasalazine. The optimal treatment algorithm has not yet been described. The purpose of this consensus statement is to outline a treatment algorithm for AA, including the indications for systemic treatment, appropriate choice of systemic treatment, satisfactory outcome measures and when to discontinue successful or unsuccessful treatment. [ABSTRACT FROM AUTHOR]

Published
2019
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