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As per the news and articles published in mass media in recent years, the usage of formalin in fruits and vegetables has become a worrisome condition in Bangladesh. In this context, this study was conducted to observe the effect of formalin on postharvest quality, shelf life, and nutritional profile of carrot, papaya, plum, apple plum, and guava. Fruits and vegetables sample were treated with different concentrations of formalin solutions (1%, 10%, 20%, and 30%) in two different modes (dipping and spraying) and stored for seven days. Physical parameters (color, texture, and flavor), weight loss, and shelf life were observed on every alternate day during the study period. Furthermore, 20% formalin-treated samples were used to find out the changes in nutritional profile (moisture, ash, carbohydrate, fat, and protein), pH, and vitamin C content. The study results revealed that different concentrations of formalin and treatment methods (dipping and spraying) did not bring up any positive effect in increasing the shelf-life and physical characteristics of selected fruits and vegetables during storage. Moreover, formalin treatment with higher concentration went in faster deterioration in color, texture, and flavor of samples compared to the control. The weight loss of fruits and vegetables is not dependent on formalin application. Formalin treatment worked negatively on the shelf life of samples. A significant reduction (P

Malnutrition refers to a nutritional ailment that functionally and clinically distresses the body. It is very common in aged people. The nutritional status of this vulnerable group in low-income countries does not remain focused upon. Therefore, this study was designed to investigate the magnitude of malnutrition and to correlate different factors amongst aged patients administered in a reputed Medical College Hospital in Dinajpur district, Bangladesh. An observational cross-sectional study was conducted to evaluate the nutritional eminence of hospitalized aged patients through the original 18-item full Mini Nutritional Assessment (MNA) screening tool. We evaluated 238 patients in this study. Of whom, 144 (60.5%) were men and 94 (39.5%) were women, whose average age were 68.7 ± 7 years. MNA revealed a prevalence of 46.2% for risk of malnutrition, 31.9% for malnutrition, and 21.8% for within normal. Aged patients who lived alone were malnourished than the patients living with others (p < 0.001). Laboratory investigation revealed that malnourished individuals had substantively decreased levels of serum albumin (2.5 ± 0.7 g/dl), hemoglobin (10.3 ± 1.7 g/dl), lymphocytes (1.4 ± 0.9×10^9/L), and cholesterol (150 ± 35.9 mg/dl). About forty-nine and 32.9 percent of individuals with malnutrition had a severe or a moderate decrease in food intakes respectively. Different health problems collectively had influenced malnutrition. Malnourished patients had a tendency to hospitalize for a longer period of time. Thus malnutrition in hospitalized aged patients was highly prevalent and was associated with low food intake, the presence of health problems, and prolonged length of hospital stay.

This study was conducted to evaluate the toxic effects of an azo dye carmoisine widely used in foods and to investigate its relation to carcinogenicity. Carmoisine administered into mice orally in four different doses as control, low, medium, and high equivalent to 0, 4, 200, and 400 mg/kg bw, respectively, for 120 days. The key toxicological endpoint was observed including animal body weight, organ weights, hematology, biochemistry, and molecular biology assessment. The body weights of medium‐ and high‐dose carmoisine‐treated mice group were significantly decreased as compared to the control mice group. Platelet, white blood cell and monocyte counts of treated group were considerably higher, while Hb and red blood cell counts were drastically lower than the control group. The biochemical parameters such as serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, total protein, globulin, urea, and creatinine level were significantly increased, while serum cholesterol level was decreased after treatment as compared to the control. RT‐PCR results showed that expression of Bcl‐x and PARP gene was intensively increased, whereas expression of p53 gene was decreased in the mouse liver tissues treated with carmoisine. This study revealed that high‐dose (400 mg/kg bw) treatment of carmoisine was attributable to renal failure and hepatotoxicity. It also would be suspected as a culprit for liver oncogenesis.