Search

Background: The numbers of infections and death by COVID-19 have continued to rise worldwide and preventive practice has remained to be one of the most effective ways to prevent it. We conducted this study to survey the knowledge, attitude, perception and practice of university students during the early stage of the pandemic in Bangladesh. Methods: This was a cross-sectional study with 305 students from Rajshahi University, conducted between March 11 and March 19, 2020. We developed a questionnaire for collecting information regarding COVID-19 following the instructions and guidelines of WHO and used frequency distribution, Kolmogorov-Smirnov test and Mann-Whitney and Kruskal-Wallis (non-parametric) tests for data analysis. Statistical significance was accepted at p < 0.05. Results: The knowledge of the students on COVID-19 was of average level; however, more than one-third of them were unwilling to avoid public transport and travel public places with friends and family. Their practice of preventive measures was not at a satisfactory level. More than one-third of them were not keen to stay home and not hesitant to visit crowded places. About half of the students thought the pandemic would not affect their daily activities, and most of them felt it would not affect their study, financial status, fieldwork of their course, or meeting with their friends and relatives. Female students were found more knowledgeable than male ones. Conclusions: The general knowledge of students had an average level on COVID-19, but their attitude, perception and preventive practices were not consistent with their level of education. The authorities should consider the findings while promulgating policies and implementing measures for the prevention of COVID-19. Doi: 10.28991/SciMedJ-2021-03-SI-9 Full Text: PDF

Backgrounds Approximately, half of the population in the world including tropical and sub-tropical climates region is at risk of dengue. Being an endemic country, Bangladesh has experienced the largest dengue epidemic in 2019. The present study aimed at evaluating the clinical and laboratory profile of dengue patients in northern Bangladesh during the epidemic. Methods This cross-sectional study included 319 serologically confirmed dengue patients admitted in Shaheed Ziaur Rahman Medical College Hospital in Bogra district. It is one of the main tertiary care hospitals in northern Bangladesh. Data were collected from July to September 2019. Patients’ clinical and laboratory data were extracted from clinical records. Patients were classified into two classes according to the WHO 2009 dengue classification such as (i) non-severe dengue and (ii) severe dengue. Chi-square test and independent t-test were used in this study. Results Of the 319 patients, 94.1% had non-severe dengue and the remaining 5.9% had severe dengue (severe plasma leakage 68.4%, severe organ involvement 68.4%, and severe clinical bleeding 10.5%). Most of the patients were suffering from primary dengue infection. The most common clinical presentation was fever followed by headache and myalgia. Vomiting and abdominal pain were the most prevalent warning signs. The common hematological findings on admission were leukopenia (63.3%), thrombocytopenia (30.4%) and increased hematocrit (26.6%). Raised serum ALT or AST was observed in 14.1% cases whereas raised serum creatinine was observed in 6.6% cases. Signs of plasma leakage (pleural effusion, respiratory distress, and ascites, rise of hematocrit >20% during hospital stay) and hepatic or renal involvement (serum ALT >42UI/L or serum creatinine >1.2 mg/dL) on admission were mostly associated with severe dengue. Conclusion The study provides clinical evidence on presentation as well as hematological and biochemical profile of dengue patients in northern Bangladesh that should be implicated in effective patient management., Author summary Dengue has become a significant public health concern worldwide in recent years especially for the South-East Asian, sub-Saharan African and Latin American countries. Bangladesh has experienced a number of outbreaks of dengue, the largest one occurred in 2019. Management of dengue cases during an epidemic is a major challenge for a limited resource country like Bangladesh. To predict the risk of developing severe dengue a combined evaluation of early symptoms and laboratory test profiles is necessary. Despite the fact, there is a lack of evidence of clinical and laboratory parameters of dengue patients in Bangladesh. Authors wanted to highlight the clinical features, and hematological and biochemical profiles of dengue patients diagnosed in Bogra district, a non-endemic zone situated in northern Bangladesh. The authors reported that fever, headache, and myalgia were the commonest presenting complaints of dengue patients whereas vomiting and abdominal pain was the most prevalent warning signs. Severe dengue was associated mostly with plasma leakage rather than hemorrhage and the rise of hematocrit during hospital stay was a predictor of severe dengue. These findings will guide physicians for prompt therapeutic management of dengue infection in the study area.

Background: The coronavirus disease 2019 (COVID-19) has continued to spread across the world with increasing number of confirmed cases and death. Preventive measures have still been the only way of slowing down the transmission and prevention of the deadly disease. Practice of preventive guidelines and perception about the disease is important in this regard. We aimed to study on practice to prevent and perception toward COVID-19 among Bangladeshi adults during the rapid rise of the outbreak.Methods: For this cross-sectional study, we conducted an online survey to collect data from 320 Bangladeshi adults during the period of 10-20 April, 2020 with a self-developed questionnaire. For measuring their level of practice, a general question was asked to participants, “Are you properly following the guidelines recommended by WHO to avoid COVID-19? Four type of perceptions; (i) seriousness, (ii) susceptibility, (iii) efficacy, and (iv) carry out the measures of the disease were considered for measuring risk of perception. Frequency distribution, Chi-square (χ2) test and binary logistic regression model were utilized in this study. Results: More than 71% of participants had good practice of always following the guidelines of the World Health Organization to prevent COVID-19. Logistic regression model demonstrated that people living in urban area (pConclusions: The good practice of preventive guidelines and risk perception toward COVID-19 among Bangladeshi adults were satisfactory but not of the expected level. High socioeconomic status and education were significantly correlated with appropriate practice and perception during the peak time of the COVID-19 pandemic. Government should take step to increase the level of practice to avoid and perception toward COVID-19 among Bangladeshi people during the pandemic.

BackgroundThe number of infection and death by COVID-19 has been rapidly increasing since December 2019 in all over the world. Until now, there is no specific treatment or vaccine for this disease; WHO suggests only some protective measures like maintaining social distance, staying home, washing hands with soap or sanitizer, wearing mask etc. The objective of this study was to survey knowledge, attitude, practice and perception regarding COVID-19 among students in Rajshahi University, Bangladesh.MethodsWe collected data from 305 students of Rajshahi University for this cross-sectional study using mixed sampling from March 11 to March 19, 2020. Frequency distribution, Mann-Whitney and Kruskal-Wallis tests were used in this study.ResultsOut of 305 participants, 224 (73.4%) and 81 (26.6%) were male and female students respectively. The study revealed that Rajshahi university students had average knowledge on symptoms, protective way and transmission of COVID-19. Female students were more knowledgeable than male. More than one third of the students had negative attitude to avoiding public transport and going out to public places with friends and family. The practice of students practice during our data collection period and in future was not satisfactory. More than one third of students were not keen to stay at home and avoid going to crowded places. The perception towards COVID-19 was not good; they had no idea whether the outbreak would affect their daily routine, study and financial matters, study field work and restrict leisure time of meeting family and relatives.ConclusionsWe found that general knowledge, attitude, practice and perception of the university students regarding COVID-19 were not satisfactory. This indicated that the situation was worse among common people. In Bangladesh, the number of healthcare providers is insufficient. University students can be employed as potential workforce to create awareness among mass people on prevention of COVID-19.

Background: Bipolar disorder (BPD) disrupts both personal and family life. In Bangladesh, studies on BPD and family issues are scanty. Therefore, we examined the impact of BPD on family relationships among married adults in Rajshahi City, Bangladesh. Methods: 708 married adults were recruited in this study, and they were selected using multistage random sampling and interviewed them with a self-developed questionnaire. The Bipolar Spectrum Disorder Scale was used for screening BPD. Interpersonal relationships and overall family relationship were measured based on the participants’ responses to four statements. Chi-square test and binary logistic regression model were used in this study. Results: This study revealed that 3.2% and 4.8% married adults had poor relationships with their spouses and family members respectively. 5.8% adults perceived they were given poor importance in decision making about family matters, and 15.8% thought the family provided poor healthcare services in their sickness. 19.9% respondents chose a poor category of overall family relationship. Wives had higher rates of poor category of interpersonal relationship factors compared to males. BPD was found as a predictor of interpersonal relationship factors among married adults: relationship with spouse (p

Background Sepsis is one of the major causes of neonatal death worldwide as well as in Bangladesh. The objective of the present study was to identify the risk factors and causative organisms of neonatal sepsis after delivery in a tertiary care hospital, Bangladesh. Methods This was a case-control study conducted in the neonatal ward of Rajshahi Medical College Hospital (RMCH), a 1000-bed tertiary hospital situated in Rajshahi, Bangladesh. Neonates diagnosed as neonatal sepsis by clinical and laboratory parameters were included as cases in this study. Admitted neonates unsuspected or undiagnosed for sepsis were considered as controls. Maternal and neonatal information and their laboratory reports were collected and analyzed. Both bivariate and multiple logistic regression models were used to identify the risk factors of neonatal sepsis. Results A total of 91 cases and 193 controls were included in the study. Maternal history of urinary tract infection (UTI) during the third trimester of pregnancy (aOR 2.75, 95% CI: 1.04–7.23, p Escherichia coli (40.7%), Staphylococcus aureus (27.5%), and Klebsiella pneumoniae (18.7%) were the commonly isolated organisms causing neonatal sepsis. All these organisms were highly resistant to common antibiotics like amoxicillin, cephalosporins, aminoglycosides and quinolones. Carbapenemase group of drugs along with amikacin, nitrofurantoin and linezolid were the most sensitive drugs. Conclusions Strengthening the existing facility for antenatal screening for early diagnosis and treatment of maternal infection during pregnancy as well as identifying high-risk pregnancy for adequate perinatal management is necessary to prevent neonatal sepsis-related morbidity and mortality. Rational use of antibiotics according to local epidemiology and culture and sensitivity reports may minimize the increasing hazards of antibiotic resistance.