227 results on '"McMurray, Gordon"'
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2. THE PRACTICAL COMPLIANCE OFFICER: TECHNICALITY VERSUS COMMERCIALITY
3. The role of TRPM8 in the Guinea-pig bladder-cooling reflex investigated using a novel TRPM8 antagonist
4. A bladder-cooling reflex in the anaesthetised guinea-pig: A model of the positive clinical ice-water test
5. Standards and qualities expected of compliance staff
6. Inward current oscillation underlying tonic contraction caused via E[T.sub.A] receptors in pig detrusor smooth muscle
7. The passive and active contractile properties of the neurogenic, underactive bladder
8. Altered distribution of interstitial cells and innervation in the rat urinary bladder following spinal cord injury
9. Identification of 5-HT2C mediated mechanisms involved in urethral sphincter reflexes in a guinea-pig model of urethral function
10. 5-HT2A receptor activation of the external urethral sphincter and 5-HT2C receptor inhibition of micturition: A study based on pharmacokinetics in the anaesthetized female rat
11. In vitro affinity optimization of an anti-BDNF monoclonal antibody translates to improved potency in targeting chronic pain states in vivo
12. Pudendal nerve stimulation of a preparation of isolated guinea-pig urethra
13. Animal models in urological disease and sexual dysfunction
14. Single-cell RNAseq reveals seven classes of colonic sensory neuron
15. Ca 2+ channel properties in smooth muscle cells of the urinary bladder from pig and human
16. MORPHOLOGICAL ASPECTS OF THE FEMALE PIG BLADDER NECK AND URETHRA: QUANTITATIVE ANALYSIS USING COMPUTER ASSISTED 3-DIMENSIONAL RECONSTRUCTIONS
17. Visceral and somatic pain modalities reveal NaV 1.7-independent visceral nociceptive pathways
18. Structural and Functional Denervation of Human Detrusor after Spinal Cord Injury
19. STUDIES OF THE PATHOPHYSIOLOGY OF IDIOPATHIC DETRUSOR INSTABILITY: THE PHYSIOLOGICAL PROPERTIES OF THE DETRUSOR SMOOTH MUSCLE AND ITS PATTERN OF INNERVATION
20. Selective 5-HT2C receptor agonists: Design and synthesis of pyridazine-fused azepines
21. Single-cell RNAseq reveals seven classes of colonic sensory neuron
22. CO-LOCALIZATION OF CARBON MONOXIDE AND NITRIC OXIDE SYNTHESIZING ENZYMES IN THE HUMAN URETHRAL SPHINCTER
23. Targeting fatty acid amide hydrolase as a therapeutic strategy for antitussive therapy
24. Residues W320 and Y328 within the binding site of the μ-opioid receptor influence opiate ligand bias
25. Visceral and somatic pain modalities reveal NaV1.7-independent visceral nociceptive pathways
26. Single-cell RNAseq reveals seven classes of colonic sensory neuron.
27. Serendipity in drug-discovery: A new series of 2-(benzyloxy)benzamides as TRPM8 antagonists
28. Genome-wide association analysis of pain severity in dysmenorrhea identifies association at chromosome 1p13.2, near the nerve growth factor locus
29. Su1933 Molecular Profiling of Colonic Sensory Neurons by In Vivo Retrograde Labelling and Single-Cell RNA Sequencing
30. Application of an Integrated GPCR SAR-Modeling Platform To Explain the Activation Selectivity of Human 5-HT2C over 5-HT2B
31. Kappa agonist CovX-Bodies
32. Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists
33. Pyrimido[4,5- d]azepines as potent and selective 5-HT 2C receptor agonists: Design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence
34. Visceral and somatic pain modalities reveal NaV1.7-independent visceral nociceptive pathways.
35. Multiparameter Optimization in CNS Drug Discovery: Design of Pyrimido[4,5-d]azepines as Potent 5-Hydroxytryptamine 2C (5-HT2C) Receptor Agonists with Exquisite Functional Selectivity over 5-HT2A and 5-HT2B Receptors
36. Co-Expression of GRK2 Reveals a Novel Conformational State of the µ-Opioid Receptor
37. Design and synthesis of pyridazinone-based 5-HT 2C agonists
38. Design and synthesis of piperazinylpyrimidinones as novel selective 5-HT 2C agonists
39. Discovery of a novel azepine series of potent and selective 5-HT 2C agonists as potential treatments for urinary incontinence
40. Purinoceptor subtypes mediating contraction and relaxation of marmoset urinary bladder smooth muscle
41. Functional Innervation of Guinea-Pig Bladder Interstitial Cells of Cajal Subtypes: Neurogenic Stimulation Evokes In Situ Calcium Transients
42. Effects of levcromakalim and nucleoside diphosphates on glibenclamide-sensitive K+ channels in pig urethral myocytes
43. Novel 2-imidazoles as potent, selective and CNS penetrant α 1A adrenoceptor partial agonists
44. Novel 2-imidazoles as potent and selective α 1A adrenoceptor partial agonists
45. The passive and active contractile properties of the neurogenic, underactive bladder
46. Identification of 5-HT2Cmediated mechanisms involved in urethral sphincter reflexes in a guinea-pig model of urethral function
47. Pyrimido[4,5-d]azepines as potent and selective 5-HT2C receptor agonists: Design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence
48. A Comparison of the 2/3/5 Selective Positive Allosteric Modulators L-838,417 and TPA023 in Preclinical Models of Inflammatory and Neuropathic Pain
49. THEORIES OF PAIN AND CONGENITAL UNIVERSAL INSENSITIVITY TO PAIN
50. ChemInform Abstract: Discovery of Novel Azepine Series of Potent and Selective 5‐HT2C Agonists as Potential Treatments for Urinary Incontinence.
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