536 results on '"McMullan R"'
Search Results
2. How to optimise duration of antibiotic treatment in patients with sepsis?
- Author
-
Hellyer, TP, Mantle, T, McMullan, R, and Dark, P
- Published
- 2020
3. Critical care usage after major gastrointestinal and liver surgery: a prospective, multicentre observational study
- Author
-
McLean, K.A., Glasbey, J.C., Borakati, A., Brooks, T.M., Chang, H.M., Choi, S.M., Goodson, R., Nielsen, M., Pronin, S., Salloum, N.L., Sewart, E., Vanniasegaram, D., Drake, T.M., Gillies, M.A., Harrison, E.M., Chapman, S.J., Khatri, C., Kong, C.Y., Claireaux, H.A., Bath, M.F., Mohan, M., McNamee, L., Kelly, M., Mitchell, H., Fitzgerald, J.E., Bhangu, A., Nepogodiev, D., Antoniou, I., Dean, R., Davies, N., Trecarten, S., Henderson, I., Holmes, C., Wylie, J., Shuttleworth, R.H., Jindal, A., Hughes, F., Gouda, P., Fleck, R., Hanrahan, M., Karunakaran, P., Chen, J.H., Sykes, M.C., Sethi, R.K., Suresh, S., Patel, P., Patel, M., Varma, R.K., Mushtaq, J., Gundogan, B., Bolton, W., Khan, T., Burke, J., Morley, R., Favero, N., Adams, R., Thirumal, V., Kennedy, E.D., Ong, K.K., Tan, Y.H., Gabriel, J., Bakhsh, A., Low, J.Y.L., Yener, A., Paraoan, V., Preece, R., Tilston, T.W., Cumber, E., Dean, S., Ross, T., McCance, E., Amin, H., Satterthwaite, L., Clement, K.D., Gratton, R., Mills, E.D., Chiu, S.M., Hung, G., Rafiq, N.M., Hayes, J.D.B., Robertson, K.L., Dynes, K., Huang, H.C., Assadullah, S., Duncumb, J.W., Moon, R.D.C., Poo, S.X., Mehta, J.K., Joshi, K.R., Callan, R., Norris, J.M., Chilvers, N.J., Keevil, H., Jull, P., Mallick, S., Elf, D., Carr, L., Player, C., Barton, E.C., Martin, A.L., Ratu, S.G., Roberts, E.J., Phan, P.N., Dyal, A.R., Rogers, J.E., Henson, A.D., Reid, N.B., Burke, D., Culleton, G., Lynne, S., Mansoor, S., Brennan, C., Blessed, R., Holloway, C., Hill, A., Goldsmith, T., Mackin, S., Kim, S., Woin, E., Brent, G., Coffin, J., Ziff, O., Momoh, Z., Debenham, R., Ahmed, M., Yong, C.S., Wan, J.C., Copley, H.C., Raut, P., Chaudhry, F.I., Nixon, G., Dorman, C., Tan, R., Kanabar, S., Canning, N., Dolaghan, M., Bell, N., McMenamin, M., Chhabra, A., Duke, K., Turner, L., Patel, T., Chew, L.S., Mirza, M., Lunawat, S., Oremule, B., Ward, N., Khan, M., Tan, E.T., Maclennan, D., McGregor, R.J., Chisholm, E.G., Griffin, E.J., Bell, L., Hughes, B.A., Davies, J., Haq, H., Ahmed, H., Ungcharoen, N., Whacha, C., Thethi, R., Markham, R.M., Lee, A.H.Y., Batt, E., Bullock, N.P., Francescon, C.T., Davies, J.E., Shafiq, N.M., Zhao, J., Vivekanantham, S., Barai, I., Allen, J.L.Y., Marshall, D.C., McIntyre, C.J., Wilson, H.C.P., Ashton, A.J., Lek, C., Behar, N., Davis-Hall, M., Seneviratne, N., Esteve, L., Sirakaya, M., Ali, S., Pope, S., Ahn, J.S., Craig-McQuaide, A., Gatfield, W.A., Leong, S., Demetri, A.M., Kerr, A.L., Rees, C., Loveday, J., Liu, S., Wijesekera, M., Maru, D., Attalla, M., Smith, N., Brown, D., Sritharan, P., Shah, A., Charavanamuttu, V., Heppenstall-Harris, G., Ng, K., Raghvani, T., Rajan, N., Hulley, K., Moody, N., Williams, M., Cotton, A., Sharifpour, M., Lwin, K.N., Bright, M., Chitnis, A.R., Abdelhadi, M., Semana, A.D., Morgan, F., Reid, R., Dickson, J., Anderson, L., McMullan, R., Ahern, N., Asmadi, A., Anderson, L.B., Boon Xuan, J. Lua, Crozier, L., McAleer, S., Lees, D.M., Adebayo, A.A., Das, M., Amphlett, A.H., Al-Robeye, A., Valli, A., Khangura, J., Winarski, A., Ali, A., Woodward, H., Gouldthrope, C., Turner, M., Sasapu, K., Tonkins, M., Wild, J.R.L., Robinson, M., Hardie, J., Heminway, R., Narramore, R., Ramjeeawon, N., Hibberd, A., Winslow, F., Ho, W., Chong, B.F., Lim, K., Ho, S., Crewdson, J.A., Singagireson, S., Kalra, N., Koumpa, F., Jhala, H., Soon, W.C., Karia, M., Rasiah, M.G., Xylas, D., Gilbert, H., Sundar-Singh, M., Wills, J., Akhtar, S., Patel, S., Hu, L., Brathwaite-Shirley, C., Nayee, H., Amin, O., Rangan, T., Turner, E.J.H., McCrann, C., Shepherd, R., Patel, N., Prest-Smith, J., Auyoung, E., Murtaza, A., Coates, A., Prys-Jones, O., King, M., Gaffney, S., Dewdney, C.J., Nehikhare, I., Lavery, J., Bassett, J., Davies, K., Ahmad, K., Collins, A., Acres, M., Egerton, C., Cheng, K., Chen, X., Chan, N., Sheldon, A., Khan, S., Empey, J., Ingram, E., Malik, A., Johnstone, M., Goodier, R., Shah, J.P., Giles, J.E., Sanders, J.A., McLure, S.W., Pal, S., Rangedara, A., Baker, A.N., Asbjoernsen, C.A., Girling, C., Gray, L., Gauntlett, L., Joyner, C., Qureshi, S., Mogan, Y.P., Ng, J.C.K., Kumar, A.N., Park, J.H., Tan, D., Choo, K.P., Raman, K.P., Buakuma, P., Xiao, C., Govinden, S., Thompson, O.D., Charalambos, M.A., Brown, E., Karsan, R.B., Dogra, T., Bullman, L.M., Dawson, P.M., Frank, A.L., Abid, H., Tung, L., Qureshi, U., Tahmina, A., Matthews, B.W., Harris, R.T., O'Connor, A., Mazan, K., Iqbal, S., Stanger, S.A., Thompson, J.D., Sullivan, J.A.L., Uppal, E., MacAskill, A., Bamgbose, F.A., Neophytou, C., Carroll, A.F., Rookes, C.W., Datta, U., Dhutia, A.J., Rashid, S., Ahmed, N., Lo, T., Bhanderi, S., Blore, C.D., Ahmed, S., Shaheen, H., Abburu, S., Majid, S., Abbas, Z., Talukdar, S.S., Burney, L.J., Patel, J.B., Al-Obaedi, O., Roberts, A.W., Mahboob, S., Singh, B., Sheth, S., Karia, P., Prabhudesai, A., Kow, K., Koysombat, K., Wang, S., Morrison, P., Maheswaran, Y., Keane, P., Copley, P.C., Brewster, O., Xu, G.X., Harries, P., Wall, C., Al-Mousawi, A., Bonsu, S., Cunha, P., Ward, T., Paul, J., Nadanakumaran, K., Tayeh, S., Holyoak, H., Remedios, J., Theodoropoulou, K., Luhishi, A., Jacob, L., Long, F., Atayi, A., Sarwar, S., Parker, O., Harvey, J., Ross, H., Rampal, R., Thomas, G., Vanmali, P., McGowan, C., Stein, J., Robertson, V., Carthew, L., Teng, V., Fong, J., Street, A.N., Thakker, C.E., O'Reilly, D., Bravo, M., Pizzolato, A., Khokhar, H.A., Ryan, M., Cheskes, L., Carr, R., Salih, A.E., Bassiony, S., Yuen, R., Chrastek, D., Rosen O'Sullivan, H., Amajuoyi, A., Wang, A., Sitta, O., Wye, J., Qamar, M.A., Major, C., Kaushal, A., Morgan, C., Petrarca, M., Allot, R., Verma, K., Dutt, S., Chilima, C.P., Peroos, S., Kosasih, S.R., Chin, H., Ashken, L., Pearse, R.J., O'Loughlin, R.A., Menon, A., Singh, K., Norton, J., Sagar, R., Jathanna, N., Rothwell, L., Watson, N., Harding, F., Dube, P., Khalid, H., Punjabi, N., Sagmeister, M., Gill, P., Shahid, S., Hudson-Phillips, S., George, D., Ashwood, J., Lewis, T., Dhar, M., Sangal, P., Rhema, I.A., Kotecha, D., Afzal, Z., Syeed, J.A., Prakash, E., Jalota, P., Herron, J., Kimani, L., Delport, A., Shukla, A., Agarwal, V., Parthiban, S., Thakur, H., Cymes, W., Rinkoff, S., Turnbull, J.A., Hayat, M., Darr, S., Khan, U., Lim, J., Higgins, A., Lakshmipathy, G., Forte, B., Canning, E., Jaitley, A., Lamont, J., Toner, E., Ghaffar, A., McDowell, M., Salmon, D., O'Carroll, O., Khan, A., Kelly, M.E., Clesham, K., Palmer, C., Lyons, R., Bell, A., Chin, R., Waldron, R.M., Trimble, A., Cox, S.E., Ashfaq, U., Campbell, J., Holliday, R.B.S., McCabe, G., Morris, F., Priestland, R., Vernon, O.K., Ledsam, A., Vaughan, R., Lim, D., Bakewell, Z.R., Hughes, R.K., Koshy, R.M., Jackson, H.R., Narayan, P., Cardwell, A.E., Jubainville, C.L., Arif, T., Elliott, L.E., Gupta, V., Bhaskaran, G., Odeleye, A., Ahmed, F., Shah, R., Pickard, J., Suleman, Y.N., North, A.S., McClymont, L.F., Hussain, N., Ibrahim, I., Ng, G.S., Wong, V., Lim, A.E., Harris, L.N., Tharmachandirar, T., Mittapalli, D., Patel, V., Lakhani, M., Bazeer, H.Z., Narwani, V., Sandhu, K.K., Wingfield, L.R., Gentry, S., Adjei, H., Bhatti, M., Braganza, L., Barnes, J., Mistry, S., Chillarge, G., Stokes, S., Cleere, J., Wadanamby, S., Bucko, A.M., Meek, J., Boxall, N., Heywood, E.G., Wiltshire, J.J., Toh, C., Ward, A.E., Shurovi, B.N., Horth, D., Patel, B.Y., Ali, B., Spencer, T., Axelson, T., Kretzmer, L., Chhina, C., Anandarajah, C., Fautz, T., Horst, C., Thevathasan, A.A., Ng, J.Q., Hirst, F., Brewer, C.F., Logan, A.E., Lockey, J.W., Forrest, P.R., Keelty, N., Wood, A.D., Springford, L.R., Avery, P., Schulz, T.M., Bemand, T.P., Howells, L., Collier, H., Khajuria, A., Tharakan, R.G., Parsons, S., Buchan, A.M., McGalliard, R.J., Mason, J.D., Cundy, O.J., Li, N., Redgrave, N.A., Watson, R.P., Pezas, T.P., Dennis, Y.F., Segall, E., Hameed, M., Lynch, A.S., Chamberlain, M., Peck, F.S., Neo, Y.N., Russell, G., Elseedawy, M., Lee, S., Foster, N.L., Soo, Y.H., Puan, L., Dennis, R., Goradia, H., Qureshi, A., Osman, S., Reeves, T., Dinsmore, L., Marsden, M., Lu, Q., Pitts-Tucker, T., Dunn, C.E., Walford, R.A., Heathcote, E., Martin, R., Pericleous, A., Brzyska, K., Reid, K.G., Williams, M.R., Wetherall, N., McAleer, E., Thomas, D., Kiff, R., Milne, S., Holmes, M.J.V., Bartlett, J., Lucas de Carvalho, J., Bloomfield, T., Tongo, F., Bremner, R.H., Yong, N., Atraszkiewicz, B.A., Mehdi, A., Tahir, M., Sherliker, G.X.J., Tear, A.K., Pandey, A., Broyd, A., Omer, H.M., Raphael, M., Chaudhry, W.W., Shahidi, S., Jawad, A.S., Gill, C.K., Fisher, I. Hindle, Adeleja, I., Clark, I.J., Aidoo-Micah, G.E., Stather, P.W., Salam, G.J., Glover, T.E., Deas, G., Sim, N.K., Obute, R.D., Wynell-Mayow, W.M., Sait, M.S., Mitha, N., de Bernier, G.L., Siddiqui, M., Shaunak, R., Wali, A., Cuthbert, G., Bhudia, R., Webb, E., Shah, S., Ansari, N., Perera, M., Kelly, N., McAllister, R., Stanley, G.H., Keane, C.P., Shatkar, V., Maxwell-Armstrong, C., Henderson, L.A., Maple, N., Manson, R., Adams, R.D., Semple, E., Mills, M., Daoub, A., Marsh, A., Ramnarine, A., Hartley, J., Malaj, M., Jewell, P.D., Whatling, E.A., Hitchen, N., Chen, M., Goh, B., Fern, J., Rogers, S., Derbyshire, L., Robertson, D.T., Abuhussein, N., Deekonda, P., Abid, A., Harrison, P.L.M., Aildasani, L., Turley, H., Sherif, M.A., Pandey, G., Filby, J.J., Johnston, A., Burke, E., Mohamud, M., Gohil, K., Tsui, A.Y., Singh, R., Lim, S.J., O'Sullivan, K., McKelvey, L.L., O'Neill, S., Roberts, H.F., Brown, F.S., Cao, Y., Buckle, R.T., Liew, Y., Sii, S., Ventre, C.M., Graham, C.J., Filipescu, T., Yousif, A., Dawar, R., Wright, A., Peters, M., Varley, R., Owczarek, S., Hartley, S., Khattak, M., Iqbal, A., Ali, M., Durrani, B., Narang, Y., Bethell, G.S., Horne, L., Pinto, R., Nicholls, K., Kisyov, I., Torrance, H.D., English, W., Lakhani, S.M., Ashraf, S.F., Venn, M., Elangovan, V., Kazmi, Z., Brecher, J., Sukumar, S., Mastan, A., Mortimer, A., Parker, J., Boyle, J., Elkawafi, M., Beckett, J., Mohite, A., Narain, A., Mazumdar, E., Sreh, A., Hague, A., Weinberg, D., Fletcher, L., Steel, M., Shufflebotham, H., Masood, M., Sinha, Y., Jenvey, C., Kitt, H., Slade, R., Craig, A.R., Deall, C., Reakes, T., Chervenkoff, J., Strange, E., O'Bryan, M., Murkin, C., Joshi, D., Bergara, T., Naqib, S., Wylam, D., Scotcher, S.E., Hewitt, C.M., Stoddart, M.T., Kerai, A., Trist, A.J., Cole, S.J., Knight, C.L., Stevens, S., Cooper, G.E., Ingham, R., Dobson, J., O'Kane, A., Moradzadeh, J., Duffy, A., Henderson, C., Ashraf, S., McLaughin, C., Hoskins, T.C., Reehal, R.S., Bookless, L.R., McLean, R.C., Stone, E.J., Wright, E.V., Abdikadir, H.R., Roberts, C., Spence, O., Srikantharajah, M., Ruiz, E.M., Matthews, J.H., Gardner, E., Hester, E., Naran, P., Simpson, R., Minhas, M., Cornish, E., Semnani, S.A., Rojoa, D., Radotra, A., Eraifej, J., Eparh, K., Smith, D.N.E., Mistry, B.D., Hickling, S.L., Din, W., Liu, C., Mithrakumar, P., Mirdavoudi, V., Rashid, M., Mcgenity, C., Hussain, O., Kadicheeni, M., Gardner, H., Anim-Addo, N., Pearce, J., Aslanyan, A., Ntala, C., Sorah, T., Parkin, J., Alizadeh, M., White, A., Edozie, F., Johnston, J., Kahar, A., Navayogaarajah, V., Patel, B., Carter, D., Khonsari, P., Burgess, A., Kong, C., Ponweera, A., Cody, A., Tan, Y., Ng, A.Y.L., Croall, A., Allan, C., Ng, S., Raghuvir, V., Telfer, R., Greenhalgh, A.D., McKerr, C.N., Edison, M.A., Patel, B.A., Dear, K., Hardy, M.R., Williams, P., Hassan, S., Sajjad, U., O'Neill, E.M., Lopes, S., Healy, L., Jamal, N., Tan, S., Lazenby, D., Husnoo, S.B., Beecroft, S., Sarvanandan, T., Weston, C., Bassam, N., Rabinthiran, S., Hayat, U., Ng, L., Varma, D., Sukkari, M., Mian, A., Omar, A., Kim, J.W., Sellathurai, J., Mahmood, J., O'Connell, C., Bose, R., Heneghan, H., Lalor, P., Matheson, J., Doherty, C., Cullen, C., Cooper, D., Angelov, S., Drislane, C., Smith, A.C.D., Kreibich, A., Palkhi, E., Durr, A., Lotfallah, A., Gold, D., Mckean, E., Dhanji, A., Anilkumar, A., Thacoor, A., Siddiqui, Z.H., Lim, S., Piquet, A., Anderson, S.M., McCormack, D.R., Gulati, J., Ibrahim, A., Murray, S.E., Walsh, S.L., McGrath, A., Ziprin, P., Chua, E.Y., Lou, C.N., Bloomer, J., Paine, H.R., Osei-Kuffour, D., White, C.J., Szczap, A., Gokani, S., Patel, K., Malys, M.K., Reed, A., Torlot, G.E., Cumber, E.M., Charania, A., Ahmad, S., Varma, N., Cheema, H., Austreng, L., Petra, H., Chaudhary, M., Zegeye, M.I., Cheung, F., Coffey, D., Heer, R.S., Singh, S., Seager, E., Cumming, S., Suresh, R.S., Verma, S., Ptacek, I.B., Gwozdz, A.M., Yang, T., Khetarpal, A.A., Shumon, S., Fung, T.M.P., Leung, W., Kwang, P., Chew, L., Loke, W., Curran, A., Chan, C., McGarrigle, C., Mohan, K., Cullen, S., Wong, E., Toale, C., Collins, D., Keane, N., Traynor, B.P., Shanahan, D., Yan, A., Jafree, D.J., Topham, C., Mitrasinovic, S., Omara, S., Bingham, G., Lykoudis, P.M., Miranda, B.H., Whitehurst, K., Kumaran, G., Devabalan, Y., Aziz, H., Shoa, M., Dindyal, S., Yates, J.A., Bernstein, I., Rattan, G., Coulson, R., Stezaker, S., Isaac, A., Salem, M., McBride, A., McFarlane, H., Yow, L., MacDonald, J., Bartlett, R.D., Turaga, S., White, U., Liew, W., Yim, N., Ang, A., Simpson, A., McAuley, D., Craig, E., Murphy, L., Shepherd, P., Kee, J.Y., Abdulmajid, A., Chung, A., Warwick, H.L., Livesey, A., Holton, P., Theodoreson, M.D., Jenkin, S.L., Turner, J., Entwisle, J.H., Marchal, S.T., O'Connor, S., Blege, H.K., Aithie, J.M., Sabine, L.M., Stewart, G.E., Jackson, S., Kishore, A., Lankage, C.M., Acquaah, F., Joyce, H.L., McKevitt, K.L., Coffey, C.J., Fawaz, A.S., Dolbec, K.S., O'Sullivan, D.A., Geraghty, J.M., Lim, E., Bolton, L., FitzPatrick, D., Robinson, C., Ramtoola, T., Collinson, S., Grundy, L., McEnhill, P.M., Harbhajan Singh, G.S., Loughran, D., Golding, D.M., Keeling, R.E., Williams, R.P., Whitham, R.D.J., Yoganathan, S., Nachiappan, R., Egan, R.J., Owasil, R., Kwan, M.L., He, A., Goh, R.W., Bhome, R., Wilson, H., Teoh, P.J., Raji, K., Jayakody, N., Matthams, J., Chong, J., Luk, C.Y., Greig, R.J., Trail, M., Charalambous, G., Rocke, A.S., Gardiner, N., Bulley, F., Warren, N., Brennan, E., Fergurson, P., Wilson, R., Whittingham, H., Brown, E.J., Khanijau, R., Gandhi, K., Morris, S., Boulton, A.J., Chandan, N., Barthorpe, A.E., Maamari, R., Sandhu, S., McCann, M., Higgs, L., Balian, V., Reeder, C., Diaper, C., Sale, T., Ali, H., Archer, C.H., Clarke, A.K., Heskin, J., Hurst, P.C., Farmer, J.D., O'Flynn, L.D., Doan, L., Shuker, B.A., Stott, G.D., Vithanage, N.A., Hoban, K.A., Nesargikar, P.N., Kennedy, H.R., Grossart, C.M., Tan, E.S.M., Roy, C.S.D., Sim, P., Leslie, K.E., Sim, D., Abul, M.H., Cody, N., Tay, A.Y., Woon, E., Sng, S., Mah, J., Robson, J., Shakweh, E., Wing, V.C., Mills, H., Li, M.M., Barrow, T.R., Balaji, S., Jordan, H.E.M., Phillips, C., Naveed, H., Hirani, S., Tai, A., Ratnakumaran, R., Sahathevan, A., Shafi, A.M.A., Seedat, M., Weaver, R., Batho, A., Punj, R., Selvachandran, H., Bhatt, N., Botchey, S., Khonat, Z., Brennan, K., Morrison, C.J., Devlin, E., Linton, A., Galloway, E., McGarvie, S., Ramsay, N., McRobbie, H.D., Whewell, H., Dean, W., Nelaj, S., Eragat, M., Mishra, A., Kane, T., Zuhair, M., Wells, M., Wilkinson, D., Woodcock, N., Sun, E., Aziz, N., and Ghaffar, M. K. Abd
- Published
- 2019
- Full Text
- View/download PDF
4. The diagnosis of invasive fungal infection in critically-ill patients using real-time PCR technology
- Author
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McMullan, R.
- Subjects
616.969307 - Published
- 2008
5. The use of high-throughput sequencing to investigate an outbreak of glycopeptide-resistant Enterococcus faecium with a novel quinupristin-dalfopristin resistance mechanism
- Author
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Shaw, Timothy D., Fairley, D. J., Schneiders, T., Pathiraja, M., Hill, R. L. R., Werner, G., Elborn, J. S., and McMullan, R.
- Published
- 2018
- Full Text
- View/download PDF
6. Analysis of exhaled breath to identify critically ill patients with ventilator‐associated pneumonia
- Author
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Felton, T. W., primary, Ahmed, W., additional, White, I. R., additional, van Oort, P., additional, Rattray, N. J. W., additional, Docherty, C., additional, Bannard‐Smith, J., additional, Morton, B., additional, Welters, I., additional, McMullan, R., additional, Roberts, S. A., additional, Goodacre, R., additional, Dark, P. M., additional, and Fowler, S. J., additional
- Published
- 2023
- Full Text
- View/download PDF
7. Nominations sought
- Author
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McMullan, R.
- Published
- 2021
- Full Text
- View/download PDF
8. Safety of Nonsteroidal Anti-inflammatory Drugs in Major Gastrointestinal Surgery: A Prospective, Multicenter Cohort Study
- Author
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Abbas, Z., Abburu, S., Abd Ghaffar, M. K., Abdelhadi, M., Abdikadir, H. R., Abdulmajid, A., Abid, H., Abid, A., Abuhussein, N., Abul, M. H., Acquaah, F., Acres, M., Adams, R., Adams, R. D., Adebayo, A. A., Adeleja, I., Adjei, H., Afzal, Z., Agarwal, V., Ahern, N., Ahmad, K., Ahmad, S., Ahmed, M., Ahmed, H., Ahmed, N., Ahmed, S., Ahmed, F., Ahn, J. S., Aidoo-Micah, G. E., Aildasani, L., Aithie, J. M., Akhtar, S., Ali, S., Ali, A., Ali, B., Ali, M., Ali, H., Alizadeh, M., Allan, C., Allen, J. L. Y., Allot, R., Al-Mousawi, A., Al-Obaedi, O., Al-Robeye, A., Amajuoyi, A., Amin, H., Amin, O., Amphlett, A. H., Anandarajah, C., Anderson, L., Anderson, L. B., Anderson, S. M., Ang, A., Angelov, S., Anilkumar, A., Anim-Addo, N., Ansari, N., Antoniou, I., Archer, C. H., Arif, T., Asbjoernsen, C. A., Ashfaq, U., Ashken, L., Ashraf, S. F., Ashraf, S., Ashton, A. J., Ashwood, J., Aslanyan, A., Asmadi, A., Assadullah, S., Atayi, A., Atraszkiewicz, B. 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- Published
- 2017
- Full Text
- View/download PDF
9. Mechanisms regulating collagenolytic and elastolytic activity in m. avium infection: S18
- Author
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McFetridge, S J, McMullan, R, Schroeder, G N, and OʼKane, C M
- Published
- 2017
- Full Text
- View/download PDF
10. Is Gaining Affective Commitment the Missing Strategy for Successful Change Management in Healthcare?
- Author
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Harrison, R, Chauhan, A, Minbashian, A, McMullan, R, Schwarz, G, Harrison, R, Chauhan, A, Minbashian, A, McMullan, R, and Schwarz, G
- Abstract
Despite the requirement for continual change and development, change failure is omnipresent in health care, ranging from small technical errors within new systems, processes or technologies, through to breakdowns and large-scale disaster. Despite decades of research investment, consultancy and initiatives, creating a healthcare context that promotes clinician engagement with change remains elusive, with limited demonstrated progress. Affective commitment to change refers to commitment that is driven by a desire to support change based on its perceived benefits or value, as opposed to commitment that is based on a sense of obligation or the minimization of costs. Recent evidence from health-care contexts indicates that affective commitment to change drives change readiness more so than the individual's self-efficacy for dealing with the change. Considering evidence regarding the effect of affective commitment to change on individual and collective change readiness among health-care staff, we may need to reorient our current strategies for managing change. We explore the opportunities to enhance affective commitment to change and, in turn, change readiness through adopting values-based approaches to designing and executing change proposals with clinicians and service users.
- Published
- 2022
11. Body mass index and complications following major gastrointestinal surgery
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Johnston A, Burke E, Mohamud M, Gohil K, Tsui AY, Singh R, Lim SJ, O'Sullivan K, McKelvey LL, O'Neill S, Roberts HF, Brown FS, Cao Y, Buckle RT, Liew Y, Sii S, Ventre CM, Graham CJ, Filipescu T, Yousif A, Dawar R, Wright A, Peters M, Varley R, Owczarek S, Hartley S, Khattak M, Iqbal A, Ali M, Durrani B, Narang Y, Bethell GS, Horne L, Pinto R, Nicholls K, Kisyov I, Torrance HD, English W, Lakhani SM, Ashraf SF, Venn M, Elangovan V, Kazmi Z, Brecher J, Sukumar S, Mastan A, Mortimer A, Parker J, Boyle J, Elkawafi M, Beckett J, Mohite A, Narain A, Mazumdar E, Sreh A, Hague A, Weinberg D, Fletcher L, Steel M, Shufflebotham H, Masood M, Sinha Y, Jenvey C, Kitt H, Slade R, Craig AR, Deall C, Reakes T, Chervenkoff J, Strange E, O'Bryan M, Murkin C, Joshi D, Bergara T, Naqib S, Wylam D, Scotcher SE, Hewitt CM, Stoddart MT, Kerai A, Trist AJ, Cole SJ, Knight CL, Stevens S, Cooper GE, Ingham R, Dobson J, O'Kane A, Moradzadeh J, Duffy A, Henderson C, Ashraf S, McLaughin C, Hoskins TC, Reehal RS, Bookless LR, McLean RC, Stone EJ, Wright EV, Abdikadir HR, Roberts C, Spence O, Srikantharajah M, Ruiz EM, Matthews JH, Gardner E, Hester E, Naran P, Simpson R, Minhas M, Cornish E, Semnani SA, Rojoa D, Radotra A, Eraifej J, Eparh K, Smith DNE, Mistry BD, Hickling SL, Din W, Liu C, Mithrakumar P, Mirdavoudi V, Rashid M, Mcgenity C, Hussain O, Kadicheeni M, Gardner H, Anim-Addo N, Pearce J, Aslanyan A, Ntala C, Sorah T, Parkin J, Alizadeh M, White A, Edozie F, Johnston J, Kahar A, Navayogaarajah V, Carter D, Khonsari P, Burgess A, Patel B, Kong C, Ponweera A, Cody A, Tan Y, Ng AYL, Croall A, Allan C, Ng S, Raghuvir V, Telfer R, Greenhalgh AD, McKerr CN, Edison MA, Patel BA, Dear K, Hardy MR, Williams P, Hassan S, Sajjad U, O'Neill EM, Lopes S, Healy L, Jamal N, Tan S, Lazenby D, Husnoo SB, Beecroft S, Sarvanandan T, Weston C, Bassam N, Rabinthiran S, Hayat U, Ng L, Varma D, Sukkari M, Mian A, Omar A, Kim JW, Sellathurai J, Mahmood J, O'Connell C, Bose R, Heneghan H, Lalor P, Matheson J, Doherty C, Cullen C, Cooper D, Angelov S, Drislane C, Smith ACD, Kreibich A, Palkhi E, Durr A, Lotfallah A, Gold D, Mckean E, Dhanji A, Anilkumar A, Thacoor A, Siddiqui ZH, Lim S, Piquet A, Anderson SM, McCormack DR, Gulati J, Ibrahim A, Murray SE, Walsh SL, McGrath A, Ziprin P, Chua EY, Lou CN, Bloomer J, Paine HR, Osei-Kuffour D, White CJ, Szczap A, Gokani S, Patel K, Malys MK, Reed A, Torlot GE, Cumber EM, Charania A, Ahmad S, Varma N, Cheema H, Austreng L, Petra H, Chaudhary M, Zegeye MI, Cheung F, Coffey D, Heer RS, Singh S, Seager E, Cumming S, Suresh RS, Verma S, Ptacek IB, Gwozdz AM, Yang T, Khetarpal AA, Shumon S, Fung TMP, Leung W, Kwang P, Chew L, Loke W, Curran A, Chan C, McGarrigle C, Mohan K, Cullen S, Wong E, Toale C, Collins D, Keane N, Traynor BP, Shanahan D, Yan A, Jafree DJ, Topham C, Mitrasinovic S, Omara S, Bingham G, Lykoudis PM, Miranda BH, Whitehurst K, Kumaran G, Devabalan Y, Aziz H, Shoa M, Dindyal S, Yates JA, Bernstein I, Rattan G, Coulson R, Stezaker S, Isaac A, Salem M, McBride A, McFarlane H, Yow L, MacDonald J, Bartlett RD, Turaga S, White U, Liew W, Yim N, Ang A, Simpson A, McAuley D, Craig E, Murphy L, Shepherd P, Kee JY, Abdulmajid A, Chung A, Warwick HL, Livesey A, Holton P, Theodoreson MD, Jenkin SL, Turner J, Entwisle JH, Marchal ST, O'Connor S, Blege HK, Aithie JM, Sabine LM, Stewart GE, Jackson S, Kishore A, Lankage CM, Acquaah F, Joyce HL, McKevitt KL, Coffey CJ, Fawaz AS, Dolbec KS, O'Sullivan DA, Geraghty JM, Lim E, Bolton L, FitzPatrick D, Robinson C, Ramtoola T, Collinson S, Grundy L, McEnhill PM, Harbhajan Singh GS, Loughran D, Golding DM, Keeling RE, Williams RP, Whitham RDJ, Yoganathan S, Nachiappan R, Egan RJ, Owasil R, Kwan ML, He A, Goh RW, Bhome R, Wilson H, Teoh PJ, Raji K, Jayakody N, Matthams J, Chong J, Luk CY, Greig RJ, Trail M, Charalambous G, Rocke AS, Gardiner N, Bulley F, Warren N, Brennan E, Fergurson P, Wilson R, Whittingham H, Brown EJ, Khanijau R, Gandhi K, Morris S, Boulton AJ, Chandan N, Barthorpe AE, Maamari R, Sandhu S, McCann M, Higgs L, Balian V, Reeder C, Diaper C, Sale T, Ali H, Archer CH, Clarke AK, Heskin J, Hurst PC, Farmer JD, O'Flynn LD, Doan L, Shuker BA, Stott GD, Vithanage NA, Hoban KA, Nesargikar PN, Kennedy HR, Grossart CM, Tan ESM, Roy CSD, Sim P, Leslie KE, Sim D, Abul MH, Cody N, Tay AY, Woon E, Sng S, Mah J, Robson J, Shakweh E, Wing VC, Mills H, Li MM, Barrow TR, Balaji S, Jordan HEM, Phillips C, Naveed H, Hirani S, Tai A, Ratnakumaran R, Sahathevan A, Shafi AMA, Seedat M, Weaver R, Batho A, Punj R, Selvachandran H, Bhatt N, Botchey S, Khonat Z, Brennan K, Morrison CJ, Devlin E, Linton A, Galloway E, McGarvie S, Ramsay N, McRobbie HD, Whewell H, Dean W, Nelaj S, Eragat M, Mishra A, Kane T, Zuhair M, Wells M, Wilkinson D, Woodcock N, Sun E, Aziz N, Abd Ghaffar MK, Bath MF, Nepogodiev D., Blanco-Colino, R, Lee, S, Kamarajah, Sk, Vasko, P, Kuiper, Sz, Farina, V, Chapman, Sj, Drake, Tm, Gavagna, L, Pasquali, S, Pata, F, Pellino, G, de la Rosa-Estadella, M, Stellingwerf, Me, Stijns, Rch, Borrellas, A, Golding, D, Ngaage, M, Van Tol, Rr, de Groof, J, de Wilt, H, Bemelman, Wa, Mcnamee, L, Espin-Basany, E, Emre Baki, B, Gecim, Ie, Can Tatar, O, Bach, S, Bhangu, A, Bresges, K, Burke, J, Claireaux, Ha, Fearnhead, N, Fitzgerald, Je, Gallagher, S, Glasbey, Jc, Gundogan, B, Harrison, Em, Hernon, J, Khatri, C, Kong, Cy, Lyons, A, Mohan, M, Morton, D, Pinkney, Td, Arezzo, A, Foppa, C, Morino, M, Rubbini, M, Selvaggi, F, Sensi, B, Sica, G, Orhalmi, J, Naccari, P, Sgrò, A, Burger, Bhcm, Fares, Da, Spijkerman, R, van Elst, Tr, Wiersema, R, Stassen, Lp, Rodriguez Garcia, R, Özkan, Bb, Tavuz, Ai, Demirci, Z, Baki, Be, Choi, Pj, O'Sullivan, H, Salman, M, Simioni, A, Colombo, F, Turati, L, Cazzola, Fe, Gallo, G, Perrotta, G, Papandrea, M, Naccari, Pm, Menduni, N, Rossi, E, Chetta, N, Romeo, F, Giordano, F, Randisi, B, Curletti, G, Kuiper, J, Costa, A, Marcos Rodrigo, A, Sanchez, A, Varo Muñoz, A, Martinez Rios, Ce, Aliseda-Jover, D, Fernandez Nieto, D, Alvarez Reyes, I, Dominguez Rodriguez, Lm, Hernandez Ros, Mi, Esteban Sinovas, O, Bartrina Soler, P, Villarejo Campos, P, Laguna Román, S, Fontanet-Soler, S, Raurich-Leandro, J, Dominguez-Prieto, V, Segura-Sampedro, Jj, Alconchel-Gago, F, Salazar-García, C, Gezen, Ae, Sahin, A, Atasoy, H, Yuksek, B, Arslan, E, Ozmen, Bb, Sen, Ay, Erol, Hi, Ucar, E, Aktas, Mk, Yurdaor, S, Mermer, S, Seyhan, U, Tosun, V, Gunaydin, Y, Ekinci, Zb, Yazkan, Z, Choi, J, Yeoh, Tsl, Jones, C, Venturini, S, Saat, Mi, Loo, J, Pike, G, Davies, Sc, Kabariti, R, Olivier, J, Hurný, M, Žebrák, R, Machačová, A, Schulzová, M, Smolák, P, Široká, M, Palyzová, H, Jaroš, J, Dušek, T, Šimáčková, B, Bartoš, M, Sotona, O, Pös, M, Karásek, D, Higgins, P, Hacking, S, Arora, E, Coughlan, G, Palanivail, N, Quill, S, Zhang, Aa, Malak, M, Maan, D, Cheema, J, Goh, Awj, Shamsul Badrin, Ak, Guinness, F, Howard James, N, Neary, A, Sebaoui, S, Gilroy, D, Petrov, G, Craven, K, Macdonald, A, Redmond, A, Brennan, D, Roche, D, O'Dwyer, M, Collins, P, Edwards, S, Doyle, J, Tiedt, L, Arthurs, B, O'Byrne, L, Kiely, A, Glynn, M, Sproule, L, Heaney, A, Li Hi Shing, S, Goh, W, Al-Nasser, Z, Al-Nasser, A, Teh, Jw, De Boni, D, Goldin, E, Ciccioli, E, Vendramin, E, Marchese, N, Bruno, M, Vinci, A, Harder, G, Morandi, V, Magnoli, M, Suppa, A, Palmieri, A, Martorana, M, Sette, M, Balagna, P, Cruciani, C, Corte, M, Ciano, P, Bagaglini, G, Montuori, M, Di Benedetto, L, Arcudi, C, Pezzuto, R, Saraceno, F, Milana, F, Franceschilli, M, Rizzi, A, Sampietro, G, Rampulla, V, Bianco, F, Boschetti, Me, Ghignone, F, Bianchini, S, Esposto, R, Riva, L, Riva, M, Cannavò, M, Arrigo, A, Giavarini, L, Colombo, Em, Trompetto, M, Clerico, G, Catalano, M, Dosa, T, El Mabruk, M, Barone, V, Pallara, E, Pasqualoni, M, Caudullo, G, Mastandrea Bonaviri, Gn, Muro, M, Pistola, I, Verardi, L, Ferrara, D, Gerardi, S, Remore, Lm, Belia, F, Del Coco, F, Larotonda, C, Botrugno, Em, Cammarota, A, Di Girolami, L, Laterza, V, Laurino, A, Paolo, G, Santocchi, P, Puccioni, C, Truma, A, Giardino, Fr, Giuffrida, A, Ripa, M, Cautiero, R, Patturelli, M, Capozzolo, A, Selvaggi, L, Facchiano, A, Milazzo, Lf, Papazachariou, Sk, Pattapola, V, Anania, G, Feo, C, Bellinato, M, Priani, P, Zigiotto, D, Troia, A, Vable, T, Piran, G, Targa, S, Pulpito, S, Tagariello, F, Fasano, A, Anconelli, D, Castiglione, F, Tognolo, L, Lopez, G, Campion, A, Tarantino, M, Sacco, R, Sammarco, G, Palmisano, S, Giacca, M, Rocco, I, Bellio, G, Favero, A, Raimondi, P, Pantalone, Mr, De Nardi, P, Notarnicola, M, Picciariello, A, Licari, L, Parinisi, Z, Fazzotta, S, Ciciliot, M, Reggiani, L, Mariani, F, Aonzo, P, Checcacci, P, Montanelli, P, Guerra, F, Skalamera, I, Staderini, F, Grandi, S, Nelli, T, de Boer, Dv, van der Pool, Aem, Janssen, Tl, El-Atmani, S, van Verschuer, Vmt, Poelman, M, Dronkers, Wj, van Steensel, L, Toorenvliet, Br, Duinhouwer, Le, Vermaas, M, Ter Bruggen, Ffja, Hogendoorn, W, van der Harst, E, van Rijckevorsel, Vajim, Bayoumy, Ab, Lap, Cr, Gooszen, Jah, Abdulrahman, N, de Roy van Zuidewijn, D, de Groof, Ej, Zijlmans, Jl, van Dalen, Ashm, Bos, K, Musters, Gd, Looijen, Rc, Fliers, Jm, Oostendorp, Se, Mosterd, Cm, Blonk, L, Jurgens, J, Ribbink, Me, Boom, M, Boersma, Am, Hidding, E, Schmidt, Pa, Mensink, G, Graus, Sa, Gastel, Mda, Veenker, Cgh, Van Heumen, Tm, Slieker, Fjb, Sedee, Wja, Löwensteyn, Yn, Amelung, Fj, de Guerre, Levm, Nota, Clma, Van Dijck, Wpm, van Wijnbergen, Jwm, Pronk, A, Kip, M, van der Zee, C, Heiloo, S, Muller, S, Verboeket, B, Oudman, T, Zope, S, Gilissen, V, Gommers, J, Cremers, D, Van der Lubbe, M, Smet, M, Ter Weele, K, de Bruin, M, Geerlings, M, Ter Horst, L, Kerimova, N, Pesser, N, Heesakkers, H, de Mees, T, de Gooyer, Jm, Willems, L, Gawria, L, Bonouvrie, D, Harms, J, Eggen, Y, Hengeveld, E, Smeets, Hj, Hoffman, Rpc, Detmers Blom, Fpn, Van Bruggen, D, Steup, Wh, Gooiker, Ga, Willems, Yr, van der Hoeven, Ac, Vallve-Bernal, M, Perez-Gandara, B, Perez, Jl, Caballero Rodriguez, E, Perez Febles, M, Protti Ruiz, Gp, Hidalgo Pujol, M, Alberti Delgado, P, Gil Barrionuevo, E, Anabitarte, O, Caballero, L, Poyato Nuñez, Fj, Prado Perez, R, de la Portilla de Juan, F, Fulgencio Barbarin, J, Elorza Echaniz, G, Mitxelena Elosegi, L, Delgado, At, Marti Gelonch, L, Gonzalez Arribas, M, De Serra Tejada, I, Alberdi San Roman, I, de Andres Olabarria, U, Fernández-Domper, L, Perez Costoya, C, Perez Arias, H, Fa Binefa, M, Becerra Nieves, M, Escalona Canal, Mg, Aldrey, I, Vazquez-Gonzalez, I, Falcon Cazas, A, Amarelo Garcia, M, Gonzalez Ruiz, Aa, Garcia Garrido, M, Simon Frapolli, V, Martinez Diaz, Jm, De la Torre Conde, C, Rodrigues Silva, K, Hernandez Kakauridze, S, Lopez Garcia, Mc, Flores Funes, D, Gómez-López de San Román, C, San Martín Bragado, M, Tejero Pintor, Fj, Pando Ruiz, B, Sánchez Estébanez, E, Roquet Puigneró, E, Pla Seró, S, Vela Polanco, Ff, Mirallas Viñas, O, Caro Gonzalez, Mp, Bertelli Puche, Jl, Gonzalez-Martinez, A, Sanchez Cambronero, M, Garcia Torres, A, Dominguez Jimenez, M, de Jesus Rodriguez Perdomo, M, Echazarreta-Gallego, E, Sánchez-Blasco, L, Del Mar López-Cuevas, M, Latras-Cortés, I, López-Vendrell, L, Díaz Padillo, A, Mestres Petit, N, Cruz Reyes, Ja, Fernandez, C, Posada, M, Moratilla Lapeña, L, Martin Morales, E, Mate-Mate, P, Garcia Cruz, G, Gorini, L, Rubio-Perez, I, Soldevila-Verdeguer, C, Jiménez-Viñas, C, Luehrman, A, Sena-Ruiz, F, Garcia-Perez, Jm, Plomer-Sanchez, M, Pujol-Cano, N, Jimenez-Segovia, M, Diaz-Jover, P, Pineño-Flores, C, Ambrona-Zafra, D, Gonzalez-Argente, Xf, Jiménez-Morillas, P, López-Mármol, R, Durán-Martínez, M, González-Crespo, A, Checa Guillen, M, Valderrama Pérez, A, Claramonte Bellmunt, O, Martí Fernández, Rm, Kasap, S, Soylemez, Zobb, Bolat, Ab, Aydar, Seyi, Birgin, Bz, Coskun, O, Cakir, Sg, Belibagli, Zo, Herken, M, Erdem, S, Kayacan, S, Kelesoglu, Y, Moran, D, Atalay, H, Kucukdiler, E, Demirci, A, Buyukkasap, C, Kuzey, A, Emral, C, Dogan, H, Cok, H, Durmaz, H, Asma, A, Ergul, B, Kaya, A, Bilicen, G, Gunay, M, Senturk, E, Baskoy, L, Besısık, Hm, Topalan, K, Piraliyev, E, Danalıoglu, An, Ilbak, A, Yıgman, S, Kara, C, Guzel, M, Inci, Et, Onsal, U, Erel, T, Cetin, Sk, Yekenkurul, E, Kasar, P, Saglam, Za, Gursoy, F, Cetinkaya, M, Aktekin, H, Bober, Dn, Mugurtay, Y, Koksal, G, Celik, S, Bektur, G, Yildirim, R, Ankarali, T, Güven, H, Yuksel, A, Semiz, A, Cise, S, Tomas, K, Ulusahin, M, Akbulut, F, Tulum, H, Bodur, S, Isler, Vc, Pektas, Am, Mutlu, D, Mericliler, M, Tansoker, I, Polat, Zp, Seyrek, N, Beyatli, S, Toto, Of, Cakaloglu, Hc, Sapci, I, Akpunarli, B, Adiyaman, C, Kobal, Bb, Gok, Z, Benli, S, Turpan, M, Kocapinar, S, Parimli, H, Acar, S, Eger, M, Yilmaz, I, Cengiz, U, Yoruk, I, Mutlu, B, Ulkucu, A, Arukan, C, Kara, B, Gokce, K, Calisgan, B, Demirci, K, Elkatroushi, T, Ayaz, B, Uzun, B, Sivrikaya, T, Goksoy, B, Eroz, E, Celik, B, Canbay Torun, B, Ekin, B, Senay, Bb, Temiz, C, Yilmaz, M, Yasar, C, Cakir, E, Subasi, A, Celik, K, Aksoy, K, Karabulut, E, Altintas, O, Bali, An, Ciftci, E, Babaoglu, H, Aljbour, A, Aljbour, I, Akcaoglu, T, Kakil, E, Taskin, O, Taskin, Rb, Topal, U, Huzmeli, E, Caliskan, T, Unal, Ag, Yurekli, Am, Sari, V, Tutam, Dn, Celen, D, Posteki, G, Demirtas, B, Yildiz, S, Kilic, E, Yalcin, Y, Kurt, A, Gozubuyuk, Y, Huseynova, S, Cinar, S, Calar, Sn, Kurklu, O, Binbuga, M, Ceylan, C, Yavuz, G, Alim, Ye, Yildirim, N, Yilmaz, S, Onar, D, Aray, E, Ozsipahi, Ac, Koc, Ge, Yetiskin, E, Kocer, Md, Ozgencil, B, Bahcecioglu, B, Hacioglu, Ad, Bilici, O, Cin, S, Uzunoglu, Ec, Cumen, Ec, Aslan, L, Erozgur, B, Zengin, T, Kullac, S, Mizan, Sr, Baykan, B, Kopac, O, Karabacak, U, Aytekin, A, Deliktas, T, Buyukkarabacak, Y, Uzun, O, Karahan, B, Turkmen, M, Akdogan, A, Uctepe, F, Bandirmali, O, Erdogan, P, Demir, F, Bozkurt, Gk, Yilmaz, T, Sheikh, Imi, Orhan, K, Balci, B, Keyif, Mf, Bilgin, S, Cantimer, E, Yaman, S, Akkaya, E, Atesavci, Sn, Arslan, U, Asik, M, Koksal, S, Murtaza, Mi, Mustafa, S, Oun, H, Sam, Zh, Brogan, A, Zaidi, R, Quinn, K, Taylor, F, Pang, G, Heath, H, Smart, 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AII - Infectious diseases, AII - Inflammatory diseases, ANS - Neuroinfection & -inflammation, APH - Quality of Care, AII - Amsterdam institute for Infection and Immunity, Paediatric Infectious Diseases / Rheumatology / Immunology, ACS - Pulmonary hypertension & thrombosis, ACS - Heart failure & arrhythmias, Blanco-Colino R, Lee S, Kamarajah SK, Vasko P, Kuiper SZ, Farina V, Chapman SJ, Drake TM, Gavagna L, Pasquali S, Pata F, Pellino G, de la Rosa-Estadella M, Stellingwerf ME, Stijns RCH, Borrellas A, Golding D, Ngaage M, Van Tol RR, de Groof J, de Wilt H, Bemelman WA, McNamee L, Espin-Basany E, Emre Baki B, Gecim IE, Can Tatar O, Bach S, Bhangu A, Bresges K, Burke J, Claireaux HA, Fearnhead N, Fitzgerald JE, Gallagher S, Glasbey JC, Gundogan B, Harrison EM, Hernon J, Khatri C, Kong CY, Lyons A, Mohan M, Morton D, Pinkney TD, Arezzo A, Foppa C, Morino M, Rubbini M, Selvaggi F, Sensi B, Sica G, Orhalmi J, Naccari P, Sgrò A, Burger BHCM, Fares DA, Spijkerman R, van Elst TR, Wiersema R, 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Sharifpour M, Lwin KN, Bright M, Chitnis AR, Abdelhadi M, Semana AD, Morgan F, Reid R, Dickson J, Anderson L, McMullan R, Ahern N, Asmadi A, Anderson LB, Lua Boon Xuan J, Crozier L, McAleer S, Lees DM, Adebayo AA, Das M, Amphlett AH, Al-Robeye A, Valli A, Khangura J, Winarski A, Woodward H, Gouldthrope C, Turner M, Sasapu K, Tonkins M, Wild JRL, Robinson M, Hardie J, Heminway R, Narramore R, Ramjeeawon N, Hibberd A, Winslow F, Ho W, Chong BF, Lim K, Ho S, Crewdson JA, Singagireson S, Kalra N, Koumpa F, Jhala H, Soon WC, Karia M, Rasiah MG, Xylas D, Gilbert H, Sundar-Singh M, Wills J, Akhtar S, Patel S, Hu L, Brathwaite-Shirley C, Nayee H, Amin O, Rangan T, Turner EJH, McCrann C, Shepherd R, Patel N, Prest-Smith J, Auyoung E, Murtaza A, Coates A, Prys-Jones O, King M, Gaffney S, Dewdney CJ, Nehikhare I, Lavery J, Bassett J, Davies K, Ahmad K, Collins A, Acres M, Egerton C, Cheng K, Chen X, Chan N, Sheldon A, Empey J, Ingram E, Malik A, Johnstone M, Goodier R, Shah JP, Giles JE, Sanders JA, McLure SW, Pal S, Rangedara A, Baker AN, Asbjoernsen CA, Girling C, Gray L, Gauntlett L, Joyner C, Qureshi S, Mogan YP, Ng JCK, Kumar AN, Park JH, Tan D, Choo KP, Raman KP, Buakuma P, Xiao C, Govinden S, Thompson OD, Charalambos MA, Karsan RB, Dogra T, Bullman LM, Dawson PM, Frank AL, Abid H, Tung L, Qureshi U, Tahmina A, Matthews BW, Harris RT, O'Connor A, Mazan K, Iqbal S, Stanger SA, Thompson JD, Sullivan JAL, Uppal E, MacAskill A, Bamgbose FA, Neophytou C, Carroll AF, Rookes CW, Datta U, Dhutia AJ, Rashid S, Ahmed N, Lo T, Bhanderi S, Blore CD, Ahmed S, Shaheen H, Abburu S, Majid S, Abbas Z, Talukdar SS, Burney LJ, Patel JB, Al-Obaedi O, Roberts AW, Mahboob S, Sheth S, Karia P, Prabhudesai A, Kow K, Koysombat K, Wang S, Morrison P, Maheswaran Y, Keane P, Copley PC, Brewster O, Xu GX, Harries P, Wall C, Al-Mousawi A, Bonsu S, Cunha P, Ward T, Paul J, Nadanakumaran K, Tayeh S, Holyoak H, Remedios J, Theodoropoulou K, Luhishi A, Jacob L, Long F, Atayi A, Sarwar S, Parker O, Harvey J, Ross H, Rampal R, Thomas G, Vanmali P, McGowan C, Stein J, Robertson V, Carthew L, Teng V, Fong J, Street AN, Thakker CE, O'Reilly D, Bravo M, Pizzolato A, Khokhar HA, Ryan M, Cheskes L, Carr R, Salih AE, Bassiony S, Yuen R, Chrastek D, Rosen O'Sullivan H, Amajuoyi A, Wang A, Sitta O, Wye J, Qamar MA, Major C, Kaushal A, Morgan C, Petrarca M, Allot R, Verma K, Dutt S, Chilima CP, Peroos S, Kosasih SR, Chin H, Ashken L, Pearse RJ, O'Loughlin RA, Menon A, Singh K, Norton J, Sagar R, Jathanna N, Rothwell L, Watson N, Harding F, Dube P, Khalid H, Punjabi N, Sagmeister M, Gill P, Shahid S, Hudson-Phillips S, George D, Ashwood J, Lewis T, Dhar M, Sangal P, Rhema IA, Kotecha D, Afzal Z, Syeed JA, Prakash E, Jalota P, Herron J, Kimani L, Delport A, Shukla A, Agarwal V, Parthiban S, Thakur H, Cymes W, Rinkoff S, Turnbull JA, Hayat M, Darr S, Khan U, Lim J, Higgins A, Lakshmipathy G, Forte B, Canning E, Jaitley A, Lamont J, Toner E, Ghaffar A, McDowell M, Salmon D, O'Carroll O, Khan A, Kelly ME, Clesham K, Palmer C, Lyons R, Bell A, Chin R, Waldron RM, Trimble A, Cox SE, Ashfaq U, Campbell J, Holliday RBS, McCabe G, Morris F, Priestland R, Vernon OK, Ledsam A, Vaughan R, Lim D, Bakewell ZR, Hughes RK, Koshy RM, Jackson HR, Narayan P, Cardwell AE, Jubainville CL, Arif T, Elliott LE, Gupta V, Bhaskaran G, Odeleye A, Ahmed F, Shah R, Pickard J, Suleman YN, North AS, McClymont LF, Hussain N, Ibrahim I, Ng GS, Wong V, Lim AE, Harris LN, Tharmachandirar T, Mittapalli D, Patel V, Lakhani M, Bazeer HZ, Narwani V, Sandhu KK, Wingfield LR, Gentry S, Adjei H, Bhatti M, Braganza L, Barnes J, Mistry S, Chillarge G, Stokes S, Cleere J, Bucko AM, Meek J, Boxall N, Heywood EG, Wiltshire JJ, Toh C, Ward AE, Shurovi BN, Horth D, Patel BY, Ali B, Spencer T, Axelson T, Kretzmer L, Chhina C, Anandarajah C, Fautz T, Horst C, Thevathasan AA, Ng JQ, Hirst F, Brewer CF, Logan AE, Lockey JW, Forrest PR, Keelty N, Wood AD, Springford LR, Avery P, Schulz TM, Bemand TP, Howells L, Collier H, Khajuria A, Tharakan RG, Parsons S, Buchan AM, McGalliard RJ, Mason JD, Cundy OJ, Li N, Redgrave NA, Watson RP, Pezas TP, Dennis YF, Segall E, Hameed M, Lynch AS, Chamberlain M, Peck FS, Neo YN, Russell G, Elseedawy M, Foster NL, Soo YH, Puan L, Dennis R, Goradia H, Qureshi A, Osman S, Reeves T, Dinsmore L, Marsden M, Lu Q, Pitts-Tucker T, Dunn CE, Walford RA, Heathcote E, Martin R, Pericleous A, Brzyska K, Reid KG, Williams MR, Wetherall N, McAleer E, Thomas D, Kiff R, Milne S, Holmes MJV, Bartlett J, Lucas de Carvalho J, Bloomfield T, Tongo F, Bremner RH, Yong N, Atraszkiewicz BA, Mehdi A, Tahir M, Sherliker GXJ, Tear AK, Pandey A, Broyd A, Omer HM, Raphael M, Chaudhry WW, Shahidi S, Jawad AS, Gill CK, Hindle Fisher I, Adeleja I, Clark IJ, Aidoo-Micah GE, Stather PW, Salam GJ, Glover TE, Deas G, Sim NK, Obute RD, Wynell-Mayow WM, Sait MS, Mitha N, de Bernier GL, Siddiqui M, Shaunak R, Wali A, Cuthbert G, Bhudia R, Webb E, Shah S, Ansari N, Perera M, Kelly N, McAllister R, Stanley GH, Keane CP, Shatkar V, Maxwell-Armstrong C, Henderson LA, Maple N, Manson R, Adams RD, Semple E, Mills M, Daoub A, Marsh A, Ramnarine A, Hartley J, Malaj M, Jewell PD, Whatling EA, Hitchen N, Chen M, Goh B, Fern J, Rogers S, Derbyshire L, Robertson DT, Deekonda P, Abid A, Harrison PLM, Aildasani L, Turley H, Sherif MA, Pandey G, Filby JJ, Johnston A, Burke E, Mohamud M, Gohil K, Tsui AY, Singh R, Lim SJ, O'Sullivan K, McKelvey LL, O'Neill S, Roberts HF, Brown FS, Cao Y, Buckle RT, Liew Y, Sii S, Ventre CM, Graham CJ, Filipescu T, Yousif A, Dawar R, Wright A, Peters M, Varley R, Owczarek S, Hartley S, Khattak M, Iqbal A, Ali M, Durrani B, Narang Y, Bethell GS, Horne L, Pinto R, Nicholls K, Kisyov I, Torrance HD, English W, Lakhani SM, Ashraf SF, Venn M, Elangovan V, Kazmi Z, Brecher J, Sukumar S, Mastan A, Mortimer A, Parker J, Boyle J, Elkawafi M, Beckett J, Mohite A, Narain A, Mazumdar E, Sreh A, Hague A, Weinberg D, Fletcher L, Steel M, Shufflebotham H, Masood M, Sinha Y, Jenvey C, Kitt H, Slade R, Craig AR, Deall C, Reakes T, Chervenkoff J, Strange E, O'Bryan M, Murkin C, Joshi D, Bergara T, Naqib S, Wylam D, Scotcher SE, Hewitt CM, Stoddart MT, Kerai A, Trist AJ, Cole SJ, Knight CL, Stevens S, Cooper GE, Ingham R, Dobson J, O'Kane A, Moradzadeh J, Duffy A, Henderson C, Ashraf S, McLaughin C, Hoskins TC, Reehal RS, Bookless LR, McLean RC, Stone EJ, Wright EV, Abdikadir HR, Roberts C, Spence O, Srikantharajah M, Ruiz EM, Matthews JH, Gardner E, Hester E, Naran P, Simpson R, Minhas M, Cornish E, Semnani SA, Rojoa D, Radotra A, Eraifej J, Eparh K, Smith DNE, Mistry BD, Hickling SL, Din W, Liu C, Mithrakumar P, Mirdavoudi V, Rashid M, Mcgenity C, Hussain O, Kadicheeni M, Gardner H, Anim-Addo N, Pearce J, Aslanyan A, Ntala C, Sorah T, Parkin J, Alizadeh M, White A, Edozie F, Johnston J, Kahar A, Navayogaarajah V, Carter D, Khonsari P, Burgess A, Patel B, Kong C, Ponweera A, Cody A, Tan Y, Ng AYL, Croall A, Allan C, Ng S, Raghuvir V, Telfer R, Greenhalgh AD, McKerr CN, Edison MA, Patel BA, Dear K, Hardy MR, Williams P, Hassan S, Sajjad U, O'Neill EM, Lopes S, Healy L, Jamal N, Tan S, Lazenby D, Husnoo SB, Beecroft S, Sarvanandan T, Weston C, Bassam N, Rabinthiran S, Hayat U, Ng L, Varma D, Sukkari M, Mian A, Omar A, Kim JW, Sellathurai J, Mahmood J, O'Connell C, Bose R, Heneghan H, Lalor P, Matheson J, Doherty C, Cullen C, Cooper D, Angelov S, Drislane C, Smith ACD, Kreibich A, Palkhi E, Durr A, Lotfallah A, Gold D, Mckean E, Dhanji A, Anilkumar A, Thacoor A, Siddiqui ZH, Lim S, Piquet A, Anderson SM, McCormack DR, Gulati J, Ibrahim A, Murray SE, Walsh SL, McGrath A, Ziprin P, Chua EY, Lou CN, Bloomer J, Paine HR, Osei-Kuffour D, White CJ, Szczap A, Gokani S, Patel K, Malys MK, Reed A, Torlot GE, Cumber EM, Charania A, Ahmad S, Varma N, Cheema H, Austreng L, Petra H, Chaudhary M, Zegeye MI, Cheung F, Coffey D, Heer RS, Singh S, Seager E, Cumming S, Suresh RS, Verma S, Ptacek IB, Gwozdz AM, Yang T, Khetarpal AA, Shumon S, Fung TMP, Leung W, Kwang P, Chew L, Loke W, Curran A, Chan C, McGarrigle C, Mohan K, Cullen S, Wong E, Toale C, Collins D, Keane N, Traynor BP, Shanahan D, Yan A, Jafree DJ, Topham C, Mitrasinovic S, Omara S, Bingham G, Lykoudis PM, Miranda BH, Whitehurst K, Kumaran G, Devabalan Y, Aziz H, Shoa M, Dindyal S, Yates JA, Bernstein I, Rattan G, Coulson R, Stezaker S, Isaac A, Salem M, McBride A, McFarlane H, Yow L, MacDonald J, Bartlett RD, Turaga S, White U, Liew W, Yim N, Ang A, Simpson A, McAuley D, Craig E, Murphy L, Shepherd P, Kee JY, Abdulmajid A, Chung A, Warwick HL, Livesey A, Holton P, Theodoreson MD, Jenkin SL, Turner J, Entwisle JH, Marchal ST, O'Connor S, Blege HK, Aithie JM, Sabine LM, Stewart GE, Jackson S, Kishore A, Lankage CM, Acquaah F, Joyce HL, McKevitt KL, Coffey CJ, Fawaz AS, Dolbec KS, O'Sullivan DA, Geraghty JM, Lim E, Bolton L, FitzPatrick D, Robinson C, Ramtoola T, Collinson S, Grundy L, McEnhill PM, Harbhajan Singh GS, Loughran D, Golding DM, Keeling RE, Williams RP, Whitham RDJ, Yoganathan S, Nachiappan R, Egan RJ, Owasil R, Kwan ML, He A, Goh RW, Bhome R, Wilson H, Teoh PJ, Raji K, Jayakody N, Matthams J, Chong J, Luk CY, Greig RJ, Trail M, Charalambous G, Rocke AS, Gardiner N, Bulley F, Warren N, Brennan E, Fergurson P, Wilson R, Whittingham H, Brown EJ, Khanijau R, Gandhi K, Morris S, Boulton AJ, Chandan N, Barthorpe AE, Maamari R, Sandhu S, McCann M, Higgs L, Balian V, Reeder C, Diaper C, Sale T, Ali H, Archer CH, Clarke AK, Heskin J, Hurst PC, Farmer JD, O'Flynn LD, Doan L, Shuker BA, Stott GD, Vithanage NA, Hoban KA, Nesargikar PN, Kennedy HR, Grossart CM, Tan ESM, Roy CSD, Sim P, Leslie KE, Sim D, Abul MH, Cody N, Tay AY, Woon E, Sng S, Mah J, Robson J, Shakweh E, Wing VC, Mills H, Li MM, Barrow TR, Balaji S, Jordan HEM, Phillips C, Naveed H, Hirani S, Tai A, Ratnakumaran R, Sahathevan A, Shafi AMA, Seedat M, Weaver R, Batho A, Punj R, Selvachandran H, Bhatt N, Botchey S, Khonat Z, Brennan K, Morrison CJ, Devlin E, Linton A, Galloway E, McGarvie S, Ramsay N, McRobbie HD, Whewell H, Dean W, Nelaj S, Eragat M, Mishra A, Kane T, Zuhair M, Wells M, Wilkinson D, Woodcock N, Sun E, Aziz N, Abd Ghaffar MK., Nepogodiev, Dmitri, Rosati, Riccardo, Nepogodiev, D., and Robotics and image-guided minimally-invasive surgery (ROBOTICS)
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Male ,obesity ,Multivariate analysis ,Gastrointestinal Diseases ,IMPACT ,Settore MED/18 - CHIRURGIA GENERALE ,Body mass index ,Body weight ,Digestive tract ,Gastrointestinal tract ,Obesity ,Postoperative complications ,Gastroenterology ,digestive tract ,Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] ,0302 clinical medicine ,Risk Factors ,Medicine ,Prospective Studies ,Prospective cohort study ,Aged ,Europe ,Female ,Gastrointestinal Neoplasms ,Humans ,Middle Aged ,Postoperative Complications ,Body Mass Index ,OUTCOMES ,body mass index ,body weight ,gastrointestinal tract ,030220 oncology & carcinogenesis ,Meta-analysis ,Urological cancers Radboud Institute for Health Sciences [Radboudumc 15] ,Cohort ,030211 gastroenterology & hepatology ,Cohort study ,medicine.medical_specialty ,Malignancy ,NO ,03 medical and health sciences ,SDG 3 - Good Health and Well-being ,business.industry ,postoperative complications ,MORTALITY ,medicine.disease ,Settore MED/18 ,Surgery ,Postoperative complication ,Postoperative Complications, Obesity, Digestive Tract, Gastrointestinal Tract, Body Mass Index, Body Weight ,business - Abstract
Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a meta-analysis of all available prospective data.Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien-Dindo Grades III-V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results.Results This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery for malignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49-2.96, P Conclusions In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease.
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- 2018
12. A Prospective Clinical Trial of a Real-Time Polymerase Chain Reaction Assay for the Diagnosis of Candidemia in Nonneutropenic, Critically Ill Adults
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McMullan, R., Metwally, L., Coyle, P. V., Hedderwick, S., McCloskey, B., O'Neill, H. J., Patterson, C. C., Thompson, G., Webb, C. H., and Hay, R. J.
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- 2008
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13. 1704P Early switch to oral antibiotic therapy in patients with low-risk neutropenic sepsis (EASI-SWITCH trial)
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Coyle, V., primary, Forde, C., additional, Adams, R., additional, Barnes, R., additional, Chau, I., additional, Clarke, M., additional, Doran, A., additional, Grayson, M., additional, McAuley, D., additional, McDowell, C., additional, Phair, G., additional, Plummer, R., additional, Thomas, A., additional, Wilson, R., additional, and McMullan, R., additional
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- 2021
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14. Low-pathogenicity mycoplasma species induce immunoparesis and are highly prevalent amongst patients with ventilator-associated pneumonia
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Nolan, TJ, Gadsby, N, Hellyer, TP, Templeton, K, McMullan, R, McKenna, J, Rennie, J, Robb, CT, Walsh, TS, Rossi, AG, Simpson, AJ, and Morris, A Conway
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- 2015
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15. The Structure and Symmetry of Crystalline Solid Solutions: A General Revision
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Vaida, M., Shimon, L. J. W., Weisinger-Lewin, Y., Frolow, F., Lahav, M., Leiserowitz, L., and McMullan, R. K.
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- 1988
16. The Crystal Structure of Deuterated Benzene
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Jeffrey, G. A., Ruble, J. R., McMullan, R. K., and Pople, J. A.
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- 1987
17. Comparison of API20C with molecular identification of Candida spp isolated from bloodstream infections. (Short Report)
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Xu, J., Millar, B.C., Moore, J.E., McClurg, R., Walker, M.J., Evans, J., Hedderwick, S., and McMullan, R.
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Hematology -- Research ,Candida -- Genetic aspects -- Identification and classification -- Research ,Health ,Identification and classification ,Genetic aspects ,Research - Abstract
A study was carried out to compare the API20C technology with polymerase chain reaction amplification and direct sequencing of the short internal transcribed spacer region 2 (ITS2) for the identification [...]
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- 2002
18. Long-term gastrointestinal outcomes after Streptococcus bovis bacteraemia
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McKenna, A. J., OʼDonnell, M. E., McMullan, R., and Irwin, T.
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- 2011
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19. The Clathrate Hydrates
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Jeffrey, G. A., primary and McMullan, R. K., additional
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- 2007
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20. Reduction in ciprofloxacin use in a university hospital correlates with increased susceptibility to both quinolone and β-lactam antibiotics in Gram-negative organisms: O91
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Troughton, J., Millar, G., Smyth, E., and McMullan, R.
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- 2010
21. Evaluation of the VITEK®2 AST N-054 test card for the detection of extended-spectrum β-lactamase production in Escherichia coli with CTX-M phenotypes
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Donaldson, H., McCalmont, M., Livermore, D. M., Rooney, P. J., Ong, G., McHenry, E., Campbell, R., and McMullan, R.
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- 2008
22. Comparison of serum and whole-blood specimens for the detection of Candida DNA in critically ill, non-neutropenic patients
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Metwally, L., Fairley, D. J., Coyle, P. V., Hay, R. J., Hedderwick, S., McCloskey, B., O’Neill, H. J., Webb, C. H., and McMullan, R.
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- 2008
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23. The impact of a PCR assay for detection of candidaemia on antifungal drug prescribing in critically ill adults: O176
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McMullan, R., Metwally, L., Coyle, P., Hedderwick, S., McCloskey, B., OʼNeill, H., Webb, H., and Hay, R.
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- 2008
24. Improving molecular detection of Candida DNA in whole blood: comparison of seven fungal DNA extraction protocols using real-time PCR
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Metwally, L., Fairley, D. J., Coyle, P. V., Hay, R. J., Hedderwick, S., McCloskey, B., OʼNeill, H. J., Webb, C. H., Elbaz, W., and McMullan, R.
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- 2008
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25. Response to Therapy, Treatment Intolerance and Tyrosine Kinase Inhibitor Cessation Eligibility in a Real-World Cohort of Chronic Myeloid Leukaemia Patients
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McMullan, R R, McConville, C, and McMullin, M F
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Tyrosine kinase inhibitor (TKI) therapy has revolutionised chronic myeloid leukaemia (CML) management, it is however associated with significant side effects and economic burden. Recent studies have demonstrated that treatment free remission is possible in certain patients. The aim of this study was to characterise a real-world population in terms of response to therapy, treatment intolerance and potential eligibility for stopping treatment. Included were 105 CML patients diagnosed in Northern Ireland from March 2009-February 2018. Response to treatment was defined as per the 2009 and 2013 European Leukaemia Net guidelines. Potential for treatment cessation was assessed as per the 2017 UK Interim Expert Opinion on Discontinuing Tyrosine Kinase Inhibitor Treatment in Clinical Practice for Treatment-Free Remission in Chronic Myeloid Leukaemia. Our cytogenetic data cohort had a 12-month complete cytogenetic response rate of 66% and the molecular data cohort had a 12-month major molecular response rate of 38%. Of those commenced on 2nd line TKI therapy 81% achieved an optimal response at 12 months. Twenty-two patients developed intolerance and required a change in TKI therapy. The commonest side effects were gastro-intestinal upset (18%), transaminitis (16%) and fluid retention (16%). In our cohort, 20% were considered eligible to stop TKI therapy. The commonest reason for ineligibility was insufficient duration of therapy (25%). We observed that 1st and 2nd line TKI therapy are effective but problems with failure and intolerance persist. Additionally, this study identifies a cohort of patients who may attempt TKI cessation using the UK Interim Expert Opinion report on TKI therapy discontinuation.
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- 2019
26. Rapid differentiation between fluconazole-sensitive and -resistant species of Candida directly from positive blood-culture bottles by real-time PCR
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Metwally, L., Hogg, G., Coyle, P. V., Hay, R. J., Hedderwick, S., McCloskey, B., OʼNeill, H. J., Ong, G. M., Thompson, G., Webb, C. H., and McMullan, R.
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- 2007
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27. Comparison of media for optimal recovery ofCandida albicans andCandida glabrata from blood culture
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Moore, JE and McMullan, R
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- 2003
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28. The epidemiology of peritonsillar abscess disease in Northern Ireland: P1346
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Hanna, B., McMullan, R., Gallagher, G., and Hedderwick, S.
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- 2005
29. The early phase epidemiology of CTX-M type extended spectrum beta lactamase-producing Escherichia coli among hospitalised patients in Belfast: P433
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McMullan, R., Loughrey, A., McCalmont, M., and Rooney, P.
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- 2005
30. Increased erythromycin resistance in clinical Campylobacter in Northern Ireland—an update
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Rao, D., Rao, J. R., Crothers, E., McMullan, R., McDowell, D., McMahon, A., Rooney, P. J., Millar, B. C., and Moore, J. E.
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- 2005
31. Catheter-related bloodstream infection in adult haematology patients: catheter removal practice and outcome
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Coyle, V.M, McMullan, R, Morris, T.C.M, Rooney, P.J, and Hedderwick, S
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- 2004
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32. Resource utilisation, length of hospital stay, and pattern of investigation during acute medical hospital admission
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McMullan, R, Silke, B, Bennett, K, and Callachand, S
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- 2004
33. Comparison of media for optimal recovery of Candida albicans and Candida glabrata from blood culture
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Moore, J E and McMullan, R
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- 2003
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34. Outcome of catheter-related bloodstream infections in adult hematology patients
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McMullan, R., Coyle, V., Morris, C., Rooney, P., and Hedderwick, S.
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- 2003
35. Clathrate Hydrates of Some Amines
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Jeffrey, G. A., Jordan, Truman H., and McMullan, R. K.
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- 1967
36. Genotypic subgrouping of clinical isolates of Candida albicans and Candida dubliniensis by 25S intron analysis
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Millar, B.C, Moore, J.E, Xu, J, Walker, M.J, Hedderwick, S, and McMullan, R
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- 2002
37. A survey of the dose of ACE inhibitors prescribed by general physicians for patients with heart failure
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McMullan, R and Silke, B
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- 2001
38. Low-pathogenicity Mycoplasma spp. alter human monocyte and macrophage function and are highly prevalent among patients with ventilator-acquired pneumonia
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Nolan, T J, Gadsby, N J, Hellyer, T P, Templeton, K E, McMullan, R, McKenna, J P, Rennie, J, Robb, C T, Walsh, T S, Rossi, A G, Conway Morris, A, Simpson, A J, Hellyer, TP [0000-0001-5346-7411], and Apollo - University of Cambridge Repository
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Lipopolysaccharides ,Male ,Critical Care ,Assisted Ventilation ,Cytokine Biology ,Bacterial Infection ,Polymerase Chain Reaction ,Monocytes ,Mycoplasma ,Phagocytosis ,Bronchoscopy ,Pneumonia, Bacterial ,Prevalence ,Humans ,Aged ,Cross Infection ,Macrophages ,Pneumonia, Ventilator-Associated ,Pneumonia ,Middle Aged ,bacterial infections and mycoses ,Innate Immunity ,United Kingdom ,respiratory tract diseases ,Intensive Care Units ,Female ,Bronchoalveolar Lavage Fluid - Abstract
Background Ventilator-acquired pneumonia (VAP) remains a significant problem within intensive care units (ICUs). There is a growing recognition of the impact of critical-illness-induced immunoparesis on the pathogenesis of VAP, but the mechanisms remain incompletely understood. We hypothesised that, because of limitations in their routine detection, Mycoplasmataceae are more prevalent among patients with VAP than previously recognised, and that these organisms potentially impair immune cell function. Methods and setting 159 patients were recruited from 12 UK ICUs. All patients had suspected VAP and underwent bronchoscopy and bronchoalveolar lavage (BAL). VAP was defined as growth of organisms at >104 colony forming units per ml of BAL fluid on conventional culture. Samples were tested for Mycoplasmataceae (Mycoplasma and Ureaplasma spp.) by PCR, and positive samples underwent sequencing for speciation. 36 healthy donors underwent BAL for comparison. Additionally, healthy donor monocytes and macrophages were exposed to Mycoplasma salivarium and their ability to respond to lipopolysaccharide and undertake phagocytosis was assessed.Results Mycoplasmataceaewerefoundin49%(95%CI 33% to 65%) of patients with VAP, compared with 14% (95% CI 9% to 25%) of patients without VAP. Patients with sterile BAL fluid had a similar prevalence to healthy donor BAL fluid (10% (95% CI 4% to 20%) vs 8% (95% CI 2% to 22%)). The most common organism identified was M. salivarium. Blood monocytes from healthy volunteers incubated with M. salivarium displayed an impaired TNF-α response to lipopolysaccharide ( p=0.0003), as did monocyte-derived macrophages (MDMs) (p=0.024). MDM exposed to M. salivarium demonstrated impaired phagocytosis ( p=0.005).Discussion and conclusions This study demonstrates a high prevalence of Mycoplasmataceae among patients with VAP, with a markedly lower prevalence among patients with suspected VAP in whom subsequent cultures refuted the diagnosis. The most common organism found, M. salivarium, is able to alter the functions of key immune cells. Mycoplasmataceae may contribute to VAP pathogenesis.
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- 2016
39. Organisation and Planning
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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40. Project Development
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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41. Sources of Finance
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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42. Environmental Science
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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43. Cost Planning
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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44. Development of the Built Environment
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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45. Tendering Methods and Cost Control
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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46. Site Investigation and Preparation
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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47. Programming
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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48. Organisations and Careers
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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49. Services Science
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Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
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- 1997
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50. Materials Science
- Author
-
Hore, A. V., primary, Kehoe, J. G., additional, McMullan, R., additional, and Penton, M. R., additional
- Published
- 1997
- Full Text
- View/download PDF
Catalog
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