513 results on '"McKinnon, Peter J."'
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2. Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
3. Genome integrity and inflammation in the nervous system
4. Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair
5. The dystonia gene THAP1 controls DNA double-strand break repair choice
6. Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
7. 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination
8. Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors
9. The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number
10. Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures
11. DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line
12. Genome Organization Drives Chromosome Fragility
13. Atm and Bax Cooperate in Ionizing Radiation-Induced Apoptosis in the Central Nervous System
14. Polynucleotide kinase-phosphatase (PNKP) mutations and neurologic disease
15. Next‐generation bromodomain inhibitors of the SWI/SNF complex enhance DNA damage and cell death in glioblastoma
16. Simultaneous Nbs1 and p53 inactivation in neural progenitors triggers high‐grade gliomas
17. PERK Activation Promotes Medulloblastoma Tumorigenesis by Attenuating Premalignant Granule Cell Precursor Apoptosis
18. Data from The Cancer-Associated ATM R3008H Mutation Reveals the Link between ATM Activation and Its Exchange
19. Supplementary Figures and Tables from The Cancer-Associated ATM R3008H Mutation Reveals the Link between ATM Activation and Its Exchange
20. Supplementary Figure Legend from Shh Pathway Activity Is Down-Regulated in Cultured Medulloblastoma Cells: Implications for Preclinical Studies
21. Supplementary Table 1 from Shh Pathway Activity Is Down-Regulated in Cultured Medulloblastoma Cells: Implications for Preclinical Studies
22. Supplementary Figure S1 from Shh Pathway Activity Is Down-Regulated in Cultured Medulloblastoma Cells: Implications for Preclinical Studies
23. TDP1 promotes assembly of non-homologous end joining protein complexes on DNA
24. ATM is required for SOD2 expression and homeostasis within the mammary gland
25. Mouse Models of DNA Double Strand Break Repair Deficiency and Cancer
26. Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors
27. Requirement for Atm in Ionizing Radiation-Induced Cell Death in the Developing Central Nervous System
28. Out of LINE: Transposons, genome integrity, and neurodegeneration
29. Mitochondrial DNA Ligase Is Dispensable for the Viability of Cultured Cells but Essential for mtDNA Maintenance
30. Tumor‐associated APE1 variant exhibits reduced complementation efficiency but does not promote cancer cell phenotypes
31. Polynucleotide kinase–phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability
32. Robust chromosomal DNA repair via alternative end-joining in the absence of X-ray repair cross-complementing protein 1 (XRCC1)
33. MODL-06. Targeting c-MET in combination with radiation is effective in MET-fusion driven high-grade glioma
34. Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation
35. Recurrent Genomic Alterations Characterize Medulloblastoma Arising from DNA Double-Strand Break Repair Deficiency
36. Ptch2 is a Potential Regulator of Mesenchymal Stem Cells
37. Ptch2 is a Potential Regulator of Mesenchymal Stem Cells
38. Selective Utilization of Nonhomologous End-Joining and Homologous Recombination DNA Repair Pathways during Nervous System Development
39. XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia
40. Gustducin and Transducin Are Present in Taste Cells
41. α Gustducin: A Taste Cell Specific G Protein Subunit Closely Related to the α Transducins
42. Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage–induced neurodegeneration
43. Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin
44. Pineal Opsin: A Nonvisual Opsin Expressed in Chick Pineal
45. A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation
46. ATR maintains select progenitors during nervous system development
47. Scythe Regulates Apoptosis-inducing Factor Stability during Endoplasmic Reticulum Stress-induced Apoptosis
48. Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair
49. DNA ligase III is critical for mtDNA integrity but not Xrccl-mediated nuclear DNA repair
50. Mouse models of DNA double-strand break repair and neurological disease
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