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1,050 results on '"McKee, Sherry A."'

1. Sex effects in predictors of smoking abstinence and neuropsychiatric adverse events in the EAGLES trial

Author

McKee, Sherry A, Lawrence, David E, Saccone, Phillip, McRae, Thomas, and Anthenelli, Robert M

Subjects
Biomedical and Clinical Sciences, Biological Psychology, Health Sciences, Psychology, Pharmacology and Pharmaceutical Sciences, Clinical Research, Minority Health, Behavioral and Social Science, Tobacco, Women's Health, Brain Disorders, Tobacco Smoke and Health, Mental Health, Substance Misuse, Prevention, 6.1 Pharmaceuticals, Respiratory, Cardiovascular, Mental health, Good Health and Well Being, Sex, Smoking cessation medication, Cessation, Neuropsychiatric adverse events
Abstract

Significance There are sex effects in abstinence outcomes across all smoking cessation medications, but there is limited information regarding sex effects on cessation-related neuropsychiatric adverse events (NPSAEs) or interactions with psychiatric status.MethodsSecondary analysis of data from EAGLES of 8144 adults who smoke cigarettes randomized to varenicline, bupropion, nicotine patch or placebo. Design characteristics included region (within/outside US), psychiatric cohort (absent/present), and treatment. Baseline variables included demographics, smoking history, prior use of study treatments, lifetime suicide-related history, and prior psychiatric co-morbidities and medication use. Design characteristics were forced into logistic regressions models, and then interactions among sex, design elements, and baseline characteristics were evaluated for NPSAEs and 6-month cessation outcomes.ResultsFindings demonstrated a significant interaction of sex and race (p

Published
2023

21. The causes and consequences of stigma among individuals involved in the criminal legal system: A systematic review.

Author

Moore, Kelly E., primary, Phillips, Sarah, additional, Kromash, Rachelle, additional, Siebert, Shania, additional, Roberts, Walter, additional, Peltier, MacKenzie, additional, Smith, Madison D., additional, Verplaetse, Terril, additional, Marotta, Phillip, additional, Burke, Catherine, additional, Allison, Genevieve, additional, and McKee, Sherry A., additional

Published
2023
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25. Sex effects in predictors of smoking abstinence and neuropsychiatric adverse events in the EAGLES trial.

Author

McKee, Sherry, McKee, Sherry, Lawrence, David, Saccone, Phillip, McRae, Thomas, Anthenelli, Robert, McKee, Sherry, McKee, Sherry, Lawrence, David, Saccone, Phillip, McRae, Thomas, and Anthenelli, Robert

Abstract

UNLABELLED: Significance There are sex effects in abstinence outcomes across all smoking cessation medications, but there is limited information regarding sex effects on cessation-related neuropsychiatric adverse events (NPSAEs) or interactions with psychiatric status. METHODS: Secondary analysis of data from EAGLES of 8144 adults who smoke cigarettes randomized to varenicline, bupropion, nicotine patch or placebo. Design characteristics included region (within/outside US), psychiatric cohort (absent/present), and treatment. Baseline variables included demographics, smoking history, prior use of study treatments, lifetime suicide-related history, and prior psychiatric co-morbidities and medication use. Design characteristics were forced into logistic regressions models, and then interactions among sex, design elements, and baseline characteristics were evaluated for NPSAEs and 6-month cessation outcomes. RESULTS: Findings demonstrated a significant interaction of sex and race (p < 0.02); Black women were more likely to report NPSAEs than Black men. For cessation outcomes, there were no significant interactions with psychiatric cohort and sex. Women vs men with higher baseline levels of smoking had lower odds of continuous abstinence. Women vs men who used varenicline previously had lower odds of continuous abstinence. For 6-month point prevalence, sex interacted with baseline cigarettes per day (p < 0.01) similar to the interaction for continuous abstinence. Sex interacted with medication (p < 0.03), such that women vs men had relatively greater success at achieving point prevalence abstinence on varenicline. CONCLUSIONS: Overall, results demonstrated important sex and racial differences in the incidence of NPSAEs, but psychiatric status did not interact with sex on cessation outcomes. Findings did support prior work demonstrating relative increased efficacy of varenicline for women.

Published
2023

29. The criminal justice system in alcohol use treatment: a nationwide analysis of racial disparities in treatment referral and completion.

Author

Stenersen, Madeline R, Peltier, MacKenzie, and McKee, Sherry A

Subjects
ALCOHOLISM treatment, PATIENT compliance, ALASKA Natives, HEALTH services accessibility, REHABILITATION of people with alcoholism, RESEARCH funding, PEOPLE of color, LOGISTIC regression analysis, TREATMENT effectiveness, RACE, ANALYSIS of variance, TREATMENT programs, CRIMINAL justice system, HEALTH equity, MEDICAL referrals, NATIVE Americans
Abstract

Background Alcohol use and the criminal justice (CJ) system have long been integrally connected in the United States and have both disproportionally impacted Communities of Color. Despite this connection, scholarly literature has largely focused on substance use as a whole, and little literature has examined the influence of race on CJ referral to alcohol treatment and treatment outcomes. Methods A total of 749,349 cases from the treatment episodes dataset discharge were used in the current study. A series of ANOVA and logistic regression analyses were conducted to examine the impact of race on (i) likelihood of referral to alcohol treatment by the CJ system and (ii) the association between CJ referral and treatment completion. Results Results revealed significant disparities in both who is referred to alcohol treatment by the CJ system and the association of that referral to treatment completion. Notably, American Indian/Alaska Native people were significantly more likely than people of all other races to be referred by the CJ system. However, American Indian/Alaska Native people showed the smallest association between CJ referral and treatment completion. Conclusions Contrary to previous literature, findings showed that referral of and positive association between CJ referral and treatment completion are not equal across people of different races. Taken together, these results highlight continued racial inequities in the role of the CJ system in alcohol treatment and the unique potential for non-CJ-related treatment to best serve people combatting alcohol use disorder. [ABSTRACT FROM AUTHOR]

Published
2024
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42. Pharmacotherapy for Co-Occurring Alcohol Use Disorder and Post-Traumatic Stress Disorder: Targeting the Opioidergic, Noradrenergic, Serotonergic, and GABAergic/Glutamatergic Systems

Author

Verplaetse, Terril L., McKee, Sherry A., and Petrakis, Ismene L.

Subjects
United States. Food and Drug Administration, Neurophysiology, Nalmefene, Substance abuse treatment, Drinking (Alcoholic beverages), Patient compliance, Comorbidity -- Drug therapy, Serotonin, Post-traumatic stress disorder -- Drug therapy, Health
Abstract

Introduction Over the past decade, 12-month alcohol use, high-risk drinking, and alcohol use disorder (AUD) have increased by 11.2%, 29.9%, and 49.4%, respectively, in the United States. (1) In addition [...]

Published
2018

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