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21 results on '"McDonald PH"'

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1. Metabolic Dysregulation Explains the Diverse Impacts of Obesity in Males and Females with Gastrointestinal Cancers.

2. Coordination games in cancer.

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3. βarrestin-1 regulates DNA repair by acting as an E3-ubiquitin ligase adaptor for 53BP1.

4. A Nonradioactive High-Throughput Screening-Compatible Cell-Based Assay to Identify Inhibitors of the Monocarboxylate Transporter Protein 1.

5. Identification of Novel, Structurally Diverse, Small Molecule Modulators of GPR119.

6. GPCRs: Emerging anti-cancer drug targets.

7. Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects.

8. The orexin 1 receptor modulates kappa opioid receptor function via a JNK-dependent mechanism.

9. The discovery of indole full agonists of the neurotensin receptor 1 (NTSR1).

10. Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists.

11. Seeking Ligand Bias: Assessing GPCR Coupling to Beta-Arrestins for Drug Discovery.

12. The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced beta-arrestin 2 interaction.

13. Augmentation of cardiac contractility mediated by the human beta(3)-adrenergic receptor overexpressed in the hearts of transgenic mice.

14. Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin.

15. Beta-Arrestins: new roles in regulating heptahelical receptors' functions.

16. Identification of a motif in the carboxyl terminus of beta -arrestin2 responsible for activation of JNK3.

17. Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3.

18. Gene transfer and models of gene therapy for the myocardium.

19. Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery.

20. Identification of NSF as a beta-arrestin1-binding protein. Implications for beta2-adrenergic receptor regulation.

21. Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer.