129 results on '"McCarthy, PJ"'
Search Results
2. Expanding the search for galaxies at z ∼ 7-10 with new nicmos parallel fields
- Author
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Henry, AL, Siana, B, Malkan, MA, Ashby, MLN, Bridge, CR, Chary, RR, Colbert, JW, Giavalisco, M, Teplitz, HI, and McCarthy, PJ
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galaxies: evolution ,galaxies: formation ,galaxies: high-redshift ,astro-ph.CO ,Astronomy & Astrophysics ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) - Abstract
We have carried out a search for galaxies at z 7-10 in 14.4arcmin 2 of new NICMOS parallel imaging taken in the Great Observatories Origins Deep Survey (5.9arcmin2), the Cosmic Origins Survey (7.2arcmin2), and SSA22 (1.3arcmin2). These images reach 5σ sensitivities of J 110 = 26.0-27.5 (AB), and combined they increase the amount of deep near-infrared data by more than 60% in fields where the investment in deep optical data has already been made. We find no z > 7 candidates in our survey area, consistent with the Bouwens et al. measurements at z 7 and 9 (over 23arcmin2), which predict 0.7 galaxies at z 7 and 7 galaxies are missed by this survey, due to incompleteness from foreground contamination by faint sources. For the case of luminosity evolution, assuming a Schecter parameterization with a typical φ* = 10-3 Mpc-3, we find M*> - 20.0 for z 7 and M*> - 20.7 for z 9 (68% confidence). This suggests that the downward luminosity evolution of Lyman break galaxies continues to z 7, although our result is marginally consistent with the z 6 luminosity function of Bouwens et al. In addition, we present newly acquired deep MMT/Megacam imaging of the z 9 candidate JD2325+1433, first presented in Henry et al. The resulting weak but significant detection at i′ indicates that this galaxy is most likely an interloper at z 2.7. © 2009. The American Astronomical Society. All rights reserved.
- Published
- 2009
3. Star formation in emission-line galaxies between redshifts of 0.8 and 1.6
- Author
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Hicks, EKS, Malkan, MA, Teplitz, HI, McCarthy, PJ, and Lin, YAN
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galaxies : distances and redshifts ,galaxies : Seyfert ,galaxies : starburst ,galaxies : statistics ,infrared : galaxies ,surveys ,astro-ph ,Astronomy & Astrophysics ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) - Abstract
Optical spectra of 14 emission-line galaxies representative of the 1999 NICMOS parallel grism Hα survey of McCarthy et al. are presented. Of the 14, 9 have emission lines confirming the redshifts found in the grism survey. The higher resolution of our optical spectra improves the redshift accuracy by a factor of 5. The [O II]/Hα values of our sample are found to be more than 2 times lower than expected from Jansen et al. This [O II]/Hα ratio discrepancy is most likely explained by additional reddening in our Hα-selected sample [on average, as much as an extra E(B- V) = 0.6], as well as by a possible stronger dependence of the [O II]/Hα ratio on galaxy luminosity than is found in local galaxies. The result is that star formation rates (SFRs) calculated from [O II] λ3727 emission, uncorrected for extinction, are found to be on average 4 ± 2 times lower than the SFRs calculated from Ha emission. Classification of emission-line galaxies as starburst or Seyfert galaxies based on comparison of the ratios [O II]/Hβ and [Ne III] λ3869/Hβ is discussed. New Seyfert 1 diagnostics using the Ha line luminosity, H-band absolute magnitude, and Hα equivalent widths are also presented. One galaxy is classified as a Seyfert 1 based on its broad emission lines, implying a comoving number density for Seyfert 1 galaxies of 2.5-2.1+5.9 × 10-5 Mpc-3. This comoving number density is a factor of 2.4-2.0+5.5times higher than estimated by other surveys.
- Published
- 2002
4. Extremely Red Objects from the NICMOS/HST Parallel Imaging Survey
- Author
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Yan, Lin, McCarthy, PJ, Weymann, RJ, Malkan, MA, Teplitz, HI, Storrie-Lombardi, LJ, Smith, M, and Dressler, A
- Subjects
astro-ph - Abstract
We present a catalog of extremely red objects discovered using the NICMOS/HSTparallel imaging database and ground-based optical follow-up observations.Within an area of 16 square arc-minutes, we detect 15 objects with $\rm R -F160W > 5$ and $\rm F160W < 21.5$. We have also obtained K-band photometry fora subset of the 15 EROs. All of the $\rm R - F160W$ selected EROs imaged atK-band have $\rm R - K > 6$. Our objects have $\rm F110W - F160W$ colors in therange of 1.3 - 2.1, redder than the cluster ellipticals at $z \sim 0.8$ andnearly 1 magnitude redder than the average population selected from the F160Wimages at the same depth. In addition, among only 22 NICMOS pointings, wedetected two groups or clusters in two fields, each contains 3 or more EROs,suggesting that extremely red galaxies may be strongly clustered. At brightmagnitudes with $\rm F160W < 19.5$, the ERO surface density is similar to whathas been measured by other surveys. At the limit of our sample, F160W = 21.5,our measured surface density is 0.94$\pm 0.24$ arcmin^{-2}. Excluding the twopossible groups/clusters and the one apparently stellar object, reduces thesurface density to 0.38$\pm 0.15$ arcmin^{-2}.
- Published
- 2000
5. The Hα luminosity function and global star formation rate from redshifts of 1-2
- Author
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Yan, L, Mccarthy, PJ, Freudling, W, Teplitz, HI, Malumuth, EM, Weymann, RJ, and Malkan, MA
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galaxies : evolution ,galaxies : luminosity function ,mass function ,astro-ph ,galaxies : luminosity function ,mass function ,Astronomy & Astrophysics ,Astronomical and Space Sciences ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry ,Atomic ,Molecular ,Nuclear ,Particle and Plasma Physics ,Physical Chemistry (incl. Structural) - Abstract
We present a luminosity function for Hα emission from galaxies at redshifts between 0.7 and 1.9 based on slitless spectroscopy with the near-infrared camera and multiobject spectrometer on the Hubble Space Telescope. The luminosity function is well fit by a Schechter function over the range 6 × 1041 < L (Hα) < 2 × 1043 ergs s-1 with L* = 7 × 1042 ergs s-1 and φ* = 1.7 × 10-3 Mpc-3 for H0 = 50 km s-1 Mpc-1 and q0 = 0.5. We derive a volume-averaged star formation rate at z = 1.3 ± 0.5 of 0.13 M⊙ yr-1 Mpc-3 without correction for extinction. The star formation rate that we derive at ∼6500 Å is a factor of 3 higher than that deduced from 2800 Å continua. If this difference is caused entirely by reddening, the extinction correction at 2800 Å is quite significant. The precise magnitude of the total extinction correction at rest-frame UV wavelengths (e.g., 2800 and 1500 Å) is sensitive to the relative spatial distribution of the stars, gas, and dust, as well as to the extinction law. In the extreme case of a homogeneous foreground dust screen and a Milky Way or LMC extinction law, we derive a total extinction at 2800 Å of 2.1 mag, or a factor of 7 correction to the UV luminosity density. If we use the Calzetti reddening curve, which was derived for the model in which stars, gas, and dust are well mixed and nebular gas suffers more extinction than stars, our estimate of A2800 is increased by more than 1 mag.
- Published
- 1999
6. Overview of JET results for optimising ITER operation
- Author
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Mailloux, J, Abid, N, Abraham, K, Abreu, P, Adabonyan, O, Adrich, P, Afanasev, V, Afzal, M, Ahlgren, T, Aho-Mantila, L, Aiba, N, Airila, M, Akhtar, M, Albanese, R, Alderson-Martin, M, Alegre, D, Aleiferis, S, Aleksa, A, Alekseev, A, Alessi, E, Aleynikov, P, Algualcil, J, Ali, M, Allinson, M, Alper, B, Alves, E, Ambrosino, G, Ambrosino, R, Amosov, V, Sunden, E, Andrew, P, Angelini, B, Angioni, C, Antoniou, I, Appel, L, Appelbee, C, Aria, S, Ariola, M, Artaserse, G, Arter, W, Artigues, V, Asakura, N, Ash, A, Ashikawa, N, Aslanyan, V, Astrain, M, Asztalos, O, Auld, D, Auriemma, F, Austin, Y, Avotina, L, Aymerich, E, Baciero, A, Bairaktaris, F, Balbin, J, Balbinot, L, Balboa, I, Balden, M, Balshaw, C, Balshaw, N, Bandaru, V, Banks, J, Baranov, Y, Barcellona, C, Barnard, A, Barnard, M, Barnsley, R, Barth, A, Baruzzo, M, Barwell, S, Bassan, M, Batista, A, Batistoni, P, Baumane, L, Bauvir, B, Baylor, L, Beaumont, P, Beckett, D, Begolli, A, Beidler, M, Bekris, N, Beldishevski, M, Belli, E, Belli, F, Belonohy, E, Ben Yaala, M, Benayas, J, Bentley, J, Bergsaker, H, Bernardo, J, Bernert, M, Berry, M, Bertalot, L, Betar, H, Beurskens, M, Bickerton, S, Bieg, B, Bielecki, J, Bierwage, A, Biewer, T, Bilato, R, Bilkova, P, Birkenmeier, G, Bishop, H, Bizarro, J, Blackburn, J, Blanchard, P, Blatchford, P, Bobkov, V, Boboc, A, Bohm, P, Bohm, T, Bolshakova, I, Bolzonella, T, Bonanomi, N, Bonfiglio, D, Bonnin, X, Bonofiglo, P, Boocock, S, Booth, A, Booth, J, Borba, D, Borodin, D, Borodkina, I, Boulbe, C, Bourdelle, C, Bowden, M, Boyd, K, Mihalic, I, Bradnam, S, Braic, V, Brandt, L, Bravanec, R, Breizman, B, Brett, A, Brezinsek, S, Brix, M, Bromley, K, Brown, B, Brunetti, D, Buckingham, R, Buckley, M, Budny, R, Buermans, J, Bufferand, H, Buratti, P, Burgess, A, Buscarino, A, Busse, A, Butcher, D, de la Cal, E, Calabro, G, Calacci, L, Calado, R, Camenen, Y, Canal, G, Cannas, B, Cappelli, M, Carcangiu, S, Card, P, Cardinali, A, Carman, P, Carnevale, D, Carr, M, Carralero, D, Carraro, L, Carvalho, I, Carvalho, P, Casiraghi, I, Casson, F, Castaldo, C, Catalan, J, Catarino, N, Causa, F, Cavedon, M, Cecconello, M, Challis, C, Chamberlain, B, Chang, C, Chankin, A, Chapman, B, Chernyshova, M, Chiariello, A, Chmielewski, P, Chomiczewska, A, Chone, L, Ciraolo, G, Ciric, D, Clark, M, Clarkson, R, Clements, C, Cleverly, M, Coad, J, Coates, P, Cobalt, A, Coccorese, V, Coelho, R, Coenen, J, Coffey, I, Colangeli, A, Colas, L, Collins, C, Collins, J, Collins, S, Conka, D, Conroy, S, Conway, B, Conway, N, Coombs, D, Cooper, P, Cooper, S, Corradino, C, Corrigan, G, Coster, D, Cox, P, Craciunescu, T, Cramp, S, Crapper, C, Craven, D, Craven, R, Esposito, M, Croci, G, Croft, D, Croitoru, A, Crombe, K, Cronin, T, Cruz, N, Crystal, C, Cseh, G, Cufar, A, Cullen, A, Curuia, M, Czarski, T, Dabirikhah, H, Dal Molin, A, Dale, E, Dalgliesh, P, Dalley, S, Dankowski, J, David, P, Davies, A, Davies, S, Davis, G, Dawson, K, Dawson, S, Day, I, De Bock, M, De Temmerman, G, De Tommasi, G, Deakin, K, Deane, J, Dejarnac, R, Del Sarto, D, Delabie, E, Del-Castillo-Negrete, D, Dempsey, A, Dendy, R, Devynck, P, Di Siena, A, Di Troia, C, Dickson, T, Dinca, P, Dittmar, T, Dobrashian, J, Doerner, R, Donne, A, Dorling, S, Dormido-Canto, S, Douai, D, Dowson, S, Doyle, R, Dreval, M, Drewelow, P, Drews, P, Drummond, G, Duckworth, P, Dudding, H, Dumont, R, Dumortier, P, Dunai, D, Dunatov, T, Dunne, M, Durodie, F, Dux, R, Dvornova, A, Eastham, R, Edwards, J, Eich, T, Eichorn, A, Eidietis, N, Eksaeva, A, El Haroun, H, Ellwood, G, Elsmore, C, Embreus, O, Emery, S, Ericsson, G, Eriksson, B, Eriksson, F, Eriksson, J, Eriksson, L, Ertmer, S, Esquembri, S, Esquisabel, A, Estrada, T, Evans, G, Evans, S, Fable, E, Fagan, D, Faitsch, M, Falessi, M, Fanni, A, Farahani, A, Farquhar, I, Fasoli, A, Faugeras, B, Fazinic, S, Felici, F, Felton, R, Fernandes, A, Fernandes, H, Ferrand, J, Ferreira, D, Ferreira, J, Ferro, G, Fessey, J, Ficker, O, Field, A, Figueiredo, A, Figueiredo, J, Fil, A, Fil, N, Finburg, P, Fiorucci, D, Fischer, U, Fishpool, G, Fittill, L, Fitzgerald, M, Flammini, D, Flanagan, J, Flinders, K, Foley, S, Fonnesu, N, Fontana, M, Fontdecaba, J, Forbes, S, Formisano, A, Fornal, T, Fortuna, L, Fortuna-Zalesna, E, Fortune, M, Fowler, C, Fransson, E, Frassinetti, L, Freisinger, M, Fresa, R, Fridstrom, R, Frigione, D, Fulop, T, Furseman, M, Fusco, V, Futatani, S, Gadariya, D, Gal, K, Galassi, D, Galazka, K, Galeani, S, Gallart, D, Galvao, R, Gao, Y, Garcia, J, Garcia-Munoz, M, Gardener, M, Garzotti, L, Gaspar, J, Gatto, R, Gaudio, P, Gear, D, Gebhart, T, Gee, S, Gelfusa, M, George, R, Gerasimov, S, Gervasini, G, Gethins, M, Ghani, Z, Gherendi, M, Ghezzi, F, Giacalone, J, Giacomelli, L, Giacometti, G, Gibson, C, Gibson, K, Gil, L, Gillgren, A, Gin, D, Giovannozzi, E, Giroud, C, Glen, R, Gloggler, S, Goff, J, Gohil, P, Goloborodko, V, Gomes, R, Goncalves, B, Goniche, M, Goodyear, A, Gore, S, Gorini, G, Gorler, T, Gotts, N, Goulding, R, Gow, E, Graham, B, Graves, J, Greuner, H, Grierson, B, Griffiths, J, Griph, S, Grist, D, Gromelski, W, Groth, M, Grove, R, Gruca, M, Guard, D, Gupta, N, Gurl, C, Gusarov, A, Hackett, L, Hacquin, S, Hager, R, Hagg, L, Hakola, A, Halitovs, M, Hall, S, Hallworth-Cook, S, Ham, C, Hamaguchi, D, Hamed, M, Hamlyn-Harris, C, Hammond, K, Harford, E, Harrison, J, Harting, D, Hatano, Y, Hatch, D, Haupt, T, Hawes, J, Hawkes, N, Hawkins, J, Hayashi, T, Hazael, S, Hazel, S, Heesterman, P, Heidbrink, B, Helou, W, Hemming, O, Henderson, S, Henriques, R, Hepple, D, Herfindal, J, Hermon, G, Hill, J, Hillesheim, J, Hizanidis, K, Hjalmarsson, A, Ho, A, Hobirk, J, Hoenen, O, Hogben, C, Hollingsworth, A, Hollis, S, Hollmann, E, Holzl, M, Homan, B, Hook, M, Hopley, D, Horsley, D, Horsten, N, Horton, A, Horton, L, Horvath, L, Hotchin, S, Howell, R, Hu, Z, Huber, A, Huber, V, Huddleston, T, Huijsmans, G, Huynh, P, Hynes, A, Iliasova, M, Imrie, D, Imrisek, M, Ingleby, J, Innocente, P, Bjork, K, Isernia, N, Ivanova-Stanik, I, Ivings, E, Jablonski, S, Jachmich, S, Jackson, T, Jacquet, P, Jarleblad, H, Jaulmes, F, Rodriguez, J, Jepu, I, Joffrin, E, Johnson, R, Johnson, T, Johnston, J, Jones, C, Jones, G, Jones, L, Jones, N, Jones, T, Joyce, A, Juarez, R, Juvonen, M, Kaltiaisenaho, T, Kaniewski, J, Kantor, A, Kappatou, A, Karhunen, J, Karkinsky, D, Kashchuk, Y, Kaufman, M, Kaveney, G, Kazakov, Y, Kazantzidis, V, Keeling, D, Kelly, R, Kempenaars, M, Kennedy, C, Kennedy, D, Kent, J, Khan, K, Khilkevich, E, Kiefer, C, Kilpelainen, J, Kim, C, Kim, H, Kim, S, King, D, King, R, Kinna, D, Kiptily, V, Kirjasuo, A, Kirov, K, Kirschner, A, Kiviniemi, T, Kizane, G, Klas, M, Klepper, C, Klix, A, Kneale, G, Knight, M, Knight, P, Knights, R, Knipe, S, Knolker, M, Knott, S, Kocan, M, Kochl, F, Kodeli, I, Kolesnichenko, Y, Kominis, Y, Kong, M, Korovin, V, Kos, B, Kos, D, Koslowski, H, Kotschenreuther, M, Koubiti, M, Koziol, K, Krasilnikov, A, Krasilnikov, V, Kresina, M, Krieger, K, Krishnan, N, Krivska, A, Kruezi, U, Kukushkin, A, Kumpulainen, H, Kurki-Suonio, T, Kurotaki, H, Kwak, S, Kwon, O, Laguardia, L, Lagzdina, E, Lahtinen, A, Laing, A, Lam, N, Lambertz, H, Lane, B, Lane, C, Neto, E, Lawson, K, Lazaros, A, Lazzaro, E, Learoyd, G, Lee, C, Lee, S, Leerink, S, Leeson, T, Lefebvre, X, Leggate, H, Lehmann, J, Lehnen, M, Leichtle, D, Leipold, F, Lengar, I, Lennholm, M, Gutierrez, E, Lepiavko, B, Leppanen, J, Lerche, E, Lescinskis, A, Lewis, J, Leysen, W, Li, L, Li, Y, Likonen, J, Linsmeier, C, Lipschultz, B, Litaudon, X, Litherland-Smith, E, Liu, F, Loarer, T, Loarte, A, Lobel, R, Lomanowski, B, Lomas, P, Lopez, J, Lorenzini, R, Loreti, S, Losada, U, Loschiavo, V, Loughlin, M, Louka, Z, Lovell, J, Lowe, T, Lowry, C, Lubbad, S, Luce, T, Lucock, R, Lukin, A, Luna, C, de la Luna, E, Lungaroni, M, Lungu, C, Lunt, T, Lutsenko, V, Lyons, B, Lyssoivan, A, Machielsen, M, Macusova, E, Maenpaa, R, Maggi, C, Maggiora, R, Magness, M, Mahesan, S, Maier, H, Maingi, R, Malinowski, K, Manas, P, Mantica, P, Mantsinen, M, Manyer, J, Manzanares, A, Maquet, P, Marceca, G, Marcenko, N, Marchetto, C, Marchuk, O, Mariani, A, Mariano, G, Marin, M, Marinelli, M, Markovic, T, Marocco, D, Marot, L, Marsden, S, Marsh, J, Marshall, R, Martellucci, L, Martin, A, Martone, R, Maruyama, S, Maslov, M, Masuzaki, S, Matejcik, S, Mattei, M, Matthews, G, Matveev, D, Matveeva, E, Mauriya, A, Maviglia, F, Mayer, M, Mayoral, M, Mazzi, S, Mazzotta, C, Mcadams, R, Mccarthy, P, Mcclements, K, Mcclenaghan, J, Mccullen, P, Mcdonald, D, Mcguckin, D, Mchugh, D, Mcintyre, G, Mckean, R, Mckehon, J, Mcmillan, B, Mcnamee, L, Mcshee, A, Meakins, A, Medley, S, Meekes, C, Meghani, K, Meigs, A, Meisl, G, Meitner, S, Menmuir, S, Mergia, K, Merriman, S, Mertens, P, Meshchaninov, S, Messiaen, A, Michling, R, Middleton, P, Middleton-Gear, D, Mietelski, J, Milanesio, D, Milani, E, Militello, F, Asp, A, Milnes, J, Milocco, A, Miloshevsky, G, Minghao, C, Minucci, S, Miron, I, Miyamoto, M, Mlynar, J, Moiseenko, V, Monaghan, P, Monakhov, I, Moody, T, Moon, S, Mooney, R, Moradi, S, Morales, J, Morales, R, Mordijck, S, Moreira, L, Morgan, L, Moro, F, Morris, J, Morrison, K, Msero, L, Moulton, D, Mrowetz, T, Mundy, T, Muraglia, M, Murari, A, Muraro, A, Muthusonai, N, Na, Y, Nabais, F, Naden, M, Naish, J, Naish, R, Napoli, F, Nardon, E, Naulin, V, Nave, M, Nedzelskiy, I, Nemtsev, G, Nesenevich, V, Nestoras, I, Neu, R, Neverov, V, Ng, S, Nicassio, M, Nielsen, A, Nina, D, Nishijima, D, Noble, C, Nobs, C, Nocente, M, Nodwell, D, Nordlund, K, Nordman, H, Normanton, R, Noterdaeme, J, Nowak, S, Nunn, E, Nystrom, H, Oberparleiter, M, Obryk, B, O'Callaghan, J, Odupitan, T, Oliver, H, Olney, R, O'Mullane, M, Ongena, J, Organ, E, Orsitto, F, Orszagh, J, Osborne, T, Otin, R, Otsuka, T, Owen, A, Oya, Y, Oyaizu, M, Paccagnella, R, Pace, N, Packer, L, Paige, S, Pajuste, E, Palade, D, Pamela, S, Panadero, N, Panontin, E, Papadopoulos, A, Papp, G, Papp, P, Parail, V, Pardanaud, C, Parisi, J, Diaz, F, Parsloe, A, Parsons, M, Parsons, N, Passeri, M, Patel, A, Pau, A, Pautasso, G, Pavlichenko, R, Pavone, A, Pawelec, E, Soldan, C, Peacock, A, Pearce, M, Peluso, E, Penot, C, Pepperell, K, Pereira, R, Pereira, T, Cippo, E, Pereslavtsev, P, von Thun, C, Pericoli, V, Perry, D, Peterka, M, Petersson, P, Petravich, G, Petrella, N, Peyman, M, Pillon, M, Pinches, S, Pintsuk, G, de Sa, W, dos Reis, A, Piron, C, Pionr, L, Pironti, A, Pitts, R, van de Plassche, K, Platt, N, Plyusnin, V, Podesta, M, Pokol, G, Poli, F, Pompilian, O, Popovichev, S, Poradzinski, M, Porfiri, M, Porkolab, M, Porosnicu, C, Porton, M, Poulipoulis, G, Predebon, I, Prestopino, G, Price, C, Price, D, Price, M, Primetzhofer, D, Prior, P, Provatas, G, Pucella, G, Puglia, P, Purahoo, K, Pusztai, I, Putignano, O, Putterich, T, Quercia, A, Rachlew, E, Radulescu, G, Radulovic, V, Rainford, M, Raj, P, Ralph, G, Ramogida, G, Rasmussen, D, Rasmussen, J, Ratta, G, Ratynskaia, S, Rebai, M, Refy, D, Reichle, R, Reinke, M, Reiser, D, Reux, C, Reynolds, S, Richiusa, M, Richyal, S, Rigamonti, D, Rimini, F, Risner, J, Riva, M, Rivero-Rodriguez, J, Roach, C, Robins, R, Robinson, S, Robson, D, Rodionov, R, Rodrigues, P, Ramos, M, Rodriguez-Fernandez, P, Romanelli, F, Romanelli, M, Romanelli, S, Romazanov, J, Rossi, R, Rowe, S, Rowlands, D, Rubel, M, Rubinacci, G, Rubino, G, Ruchko, L, Ruiz, M, Ruiz, J, Ruset, C, Rzadkiewicz, J, Saarelma, S, Safi, E, Sahlberg, A, Salewski, M, Salmi, A, Salmon, R, Salzedas, F, Sanders, I, Sandiford, D, Santos, B, Santucci, A, Sarkimaki, K, Sarwar, R, Sarychev, I, Sauter, O, Sauwan, P, Scapin, N, Schluck, F, Schmid, K, Schmuck, S, Schneider, M, Schneider, P, Schworer, D, Scott, G, Scott, M, Scraggs, D, Scully, S, Segato, M, Seo, J, Sergienko, G, Sertoli, M, Sharapov, S, Shaw, A, Sheikh, H, Sheikh, U, Shepherd, A, Shevelev, A, Shigin, P, Shinohara, K, Shiraiwa, S, Shiraki, D, Short, M, Sias, G, Silburn, S, Silva, A, Silva, C, Silva, J, Silvagni, D, Simfukwe, D, Simpson, J, Sinclair, D, Sipila, S, Sips, A, Siren, P, Sirinelli, A, Sjostrand, H, Skinner, N, Slater, J, Smith, N, Smith, P, Snell, J, Snoep, G, Snoj, L, Snyder, P, Soare, S, Solano, E, Solokha, V, Somers, A, Sommariva, C, Soni, K, Sorokovoy, E, Sos, M, Sousa, J, Sozzi, C, Spagnolo, S, Spelzini, T, Spineanu, F, Spong, D, Sprada, D, Sridhar, S, Srinivasan, C, Stables, G, Staebler, G, Stamatelatos, I, Stancar, Z, Staniec, P, Stankunas, G, Stead, M, Stefanikova, E, Stephen, A, Stephens, J, Stevenson, P, Stojanov, M, Strand, P, Strauss, H, Strikwerda, S, Strom, P, Stuart, C, Studholme, W, Subramani, M, Suchkov, E, Sumida, S, Sun, H, Susts, T, Svensson, J, Svoboda, J, Sweeney, R, Sytnykov, D, Szabolics, T, Szepesi, G, Tabia, B, Tadic, T, Tal, B, Tala, T, Tallargio, A, Tamain, P, Tan, H, Tanaka, K, Tang, W, Tardocchi, M, Taylor, D, Teimane, A, Telesca, G, Teplova, N, Teplukhina, A, Terentyev, D, Terra, A, Terranova, D, Terranova, N, Testa, D, Tholerus, E, Thomas, J, Thoren, E, Thorman, A, Tierens, W, Tinguely, R, Tipton, A, Todd, H, Tokitani, M, Tolias, P, Tomes, M, Tookey, A, 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AP, van de Plassche, KL, Poli, FM, Pompilian, OG, Porfiri, MT, Rasmussen, JJ, Richiusa, ML, Rimini, FG, Roach, CM, Ramos, MR, Ruiz, JR, Schneider, PA, Sharapov, SE, Silburn, SA, Sipila, SK, Sips, ACC, Solano, ER, Strauss, HR, Stuart, CI, Sun, HJ, Susts, TE, Teimane, AS, Tinguely, RA, Turner, MM, Olivares, PV, Rinati, GV, Virtanen, AJ, Walkden, NR, Maxwell, HW, Williams, JC, Wright, JC, Zabolockis, RJ, Zaitsev, FS, Fernandez, DZ, Zastrow, KD, and Zotta, VK
- Abstract
The JET 2019-2020 scientific and technological programme exploited the results of years of concerted scientific and engineering work, including the ITER-like wall (ILW: Be wall and W divertor) installed in 2010, improved diagnostic capabilities now fully available, a major neutral beam injection upgrade providing record power in 2019-2020, and tested the technical and procedural preparation for safe operation with tritium. Research along three complementary axes yielded a wealth of new results. Firstly, the JET plasma programme delivered scenarios suitable for high fusion power and alpha particle (alpha) physics in the coming D-T campaign (DTE2), with record sustained neutron rates, as well as plasmas for clarifying the impact of isotope mass on plasma core, edge and plasma-wall interactions, and for ITER pre-fusion power operation. The efficacy of the newly installed shattered pellet injector for mitigating disruption forces and runaway electrons was demonstrated. Secondly, research on the consequences of long-term exposure to JET-ILW plasma was completed, with emphasis on wall damage and fuel retention, and with analyses of wall materials and dust particles that will help validate assumptions and codes for design and operation of ITER and DEMO. Thirdly, the nuclear technology programme aiming to deliver maximum technological return from operations in D, T and D-T benefited from the highest D-D neutron yield in years, securing results for validating radiation transport and activation codes, and nuclear data for ITER.
- Published
- 2022
7. First principles and integrated modelling achievements towards trustful fusion power predictions for JET and ITER
- Author
-
Garcia, J., Dumont, R. J., Joly, J., Morales, J., Garzotti, L., Bache, T. W., Baranov, Y., Casson, F. J., Challis, C., Kirov, K., Mailloux, J., Saarelma, S., Nocente, M., Banon-Navarro, A., Goerler, T., Citrin, J., Ho, A., Gallart, D., Mantsinen, M., Abduallev, (Abduallev, S, ( 8, S., 42, ), Abhangi, (Abhangi, M, ( 8, M., 54, ), Abreu, (Abreu, P, ( 8, P., 60, ), Afanasev, (Afanasev, V, V)(, 8, 61, ), Afzal, (Afzal, M, 14, ), Aggarwal, (Aggarwal, Km, ( 8, K. M., 85, ), Ahlgren, (Ahlgren, T, ( 8, T., 106, ), Aho-Mantila, (Aho-Mantila, L, ( 8, L., 113, ), Aiba, (Aiba, N, ( 8, N., 73, ), Airila, (Airila, M, Alarcon, (Alarcon, T, 15, ), Albanese, (Albanese, R, ( 8, R., 18, ), Alegre, (Alegre, D, ( 8, D., 64, ), Aleiferis, (Aleiferis, S, 75, ), Alessi, (Alessi, E, ( 8, E., 50, ), Aleynikov, (Aleynikov, P, 62, ), Alkseev, (Alkseev, A, ( 8, A., 76, ), Allinson, (Allinson, M, Alper, (Alper, B, ( 8, B., Alves, (Alves, E, Ambrosino, (Ambrosino, G, ( 8, G., (Ambrosino, R, Amosov, (Amosov, V, 95, ), Sunden, (Sunden, Ea, Andersson)( 8, E., 26, ), Andrews, (Andrews, R, Angelone, (Angelone, M, 96, ), Anghel, (Anghel, M, 92, ), Angioni, (Angioni, C, ( 8, C., 68, ), Appel, (Appel, L, Appelbee, (Appelbee, C, Arena, Paolo Pietro, (Arena, P, 34, ), Ariola, (Ariola, M, Arshad, (Arshad, S, 45, ), Artaud, (Artaud, J, ( 8, J., Arter, (Arter, W, ( 8, W., Ash, (Ash, A, Ashikawa, (Ashikawa, N, ( 8 ), N., Aslanyan, (Aslanyan, V, 70, ), Asunta, (Asunta, O, ( 8, O., Asztalos, 9, (Asztalos, O, 114, ), Auriemma, (Auriemma, F, ( 8, F., 19, ), Austin, (Austin, Y, ( 8, Y., Avotina, (Avotina, L, 109, ), Axton, (Axton, M, Ayres, (Ayres, C, Baciero, (Baciero, A, Baiao, (Baiao, D, Balboa, (Balboa, I, I)(, 8, Balden, (Balden, M, Balshaw, (Balshaw, N, Bandaru, (Bandaru, Vk, ( 8, V. 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Meigh, S, Meigs, Ag, Meisl, G, Meiter, S, Meitner, S, Meneses, L, Menmuir, S, Mergia, K, Merle, A, Merriman, P, Mertens, P, Meshchaninov, S, Messiaen, A, Meyer, H, Michling, R, Milanesio, D, Militello, F, Militello-Asp, E, Milocco, A, Miloshevsky, G, Mink, F, Minucci, S, Miron, I, Mistry, S, Miyoshi, Y, Mlynar, J, Moiseenko, V, Monaghan, P, Monakhov, I, Moon, S, Mooney, R, Moradi, S, Moran, J, Mordijck, S, Moreira, L, Moro, F, Morris, J, Moser, L, Mosher, S, Moulton, D, Mrowetz, T, Muir, A, Muraglia, M, Murari, A, Muraro, A, Murphy, S, Muscat, P, Muthusonai, N, Myers, C, Asakura, Nn, N'Konga, B, Nabais, F, Naish, R, Naish, J, Nakano, T, Napoli, F, Nardon, E, Naulin, V, Nave, Mff, Nedzelskiy, I, Nemtsev, G, Nesenevich, V, Nespoli, F, Neto, A, Neu, R, Neverov, V, Newman, M, Ng, S, Nicassio, M, Nielsen, Ah, Nina, D, Nishijima, D, Noble, C, Nobs, Cr, Nodwell, D, Nordlund, K, Nordman, H, Normanton, R, Noterdaeme, Jm, Nowak, S, Nunes, I, O'Gorman, T, O'Mullane, M, Oberkofler, M, Oberparleiter, M, Odupitan, T, Ogawa, Mt, Okabayashi, M, Oliver, H, Olney, R, Omoregie, L, Ongena, J, Orsitto, F, Orszagh, J, Osborne, T, Otin, R, Owen, A, Owen, T, Paccagnella, R, Packer, Lw, Pajuste, E, Pamela, S, Panja, S, Papp, P, Papp, G, Parail, V, Pardanaud, C, Diaz, Fp, Parsloe, A, Parsons, N, Parsons, M, Pasqualotto, R, Passeri, M, Patel, A, Pathak, S, Patten, H, Pau, A, Pautasso, G, Pavlichenko, R, Pavone, A, Pawelec, E, Soldan, Cp, Peackoc, A, Pehkonen, Sp, Peluso, E, Penot, C, Penzo, J, Pepperell, K, Pereira, R, Cippo, Ep, von Thun, Cp, Pericoli, V, Peruzzo, S, Peterka, M, Petersson, P, Petravich, G, Petre, A, Petrzilka, V, Philipps, V, Pigatto, L, Pillon, M, Pinches, S, Pintsuk, G, Piovesan, P, de Sa, Wp, dos Reis, Ap, Piron, L, Piron, C, Pironti, A, Pisano, F, Pitts, R, Plyusnin, V, Poli, Fm, Pomaro, N, Pompilian, Og, Pool, P, Popovichev, S, Poradzinski, M, Porfiri, Mt, Porosnicu, C, Porton, M, Possnert, G, Potzel, S, Poulipoulis, G, Powell, T, Prajapati, V, Prakash, R, Predebon, I, Prestopino, G, Price, D, Price, M, Price, R, Primetzhofer, D, Prior, P, Pucella, G, Puglia, P, Puiatti, Me, Purahoo, K, Pusztai, I, Putterich, T, Rachlew, E, Rack, M, Ragona, R, Rainford, M, Raj, P, Rakha, A, Ramogida, G, Ranjan, S, Rapson, Cj, Rasmussen, D, Rasmussen, Jj, Rathod, K, Ratta, G, Ratynskaia, S, Ravera, G, Rebai, M, Reed, A, Refy, D, Regana, J, Reich, M, Reid, N, Reimold, F, Reinhart, M, Reinke, M, Reiser, D, Rendell, D, Reux, C, Cortes, Sdar, Reynolds, S, Ricci, D, Richiusa, M, Rigamonti, D, Rimini, Fg, Risner, J, Riva, M, Rivero-Rodriguez, J, Roach, C, Robins, R, Robinson, S, Robson, D, Rodionov, R, Rodrigues, P, Rodriguez, J, Rohde, V, Romanelli, M, Romanelli, F, Romanelli, S, Romazanov, J, Rowe, S, Rubel, M, Rubinacci, G, Rubino, G, Ruchko, L, Ruset, C, Rzadkiewicz, J, Sabot, R, Saez, X, Safi, E, Sahlberg, A, Saibene, G, Saleem, M, Salewski, M, Salmi, A, Salmon, R, Salzedas, F, Samm, U, Sandiford, D, Santa, P, Santala, Mik, Santos, B, Santucci, A, Sartori, F, Sartori, R, Sauter, O, Scannell, R, Schluck, F, Schlummer, T, Schmid, K, Schmuck, S, Schopf, K, Schweinzer, J, Schworer, D, Scott, Sd, Sergienko, G, Sertoli, M, Shabbir, A, Sharapov, Se, Shaw, A, Sheikh, H, Shepherd, A, Shevelev, A, Shiraki, D, Shumack, A, Sias, G, Sibbald, M, Sieglin, B, Silburn, S, Silva, J, Silva, A, Silva, C, Silvagni, D, Simmons, P, Simpson, J, Sinha, A, Sipila, Sk, Sips, Acc, Siren, P, Sirinelli, A, Sjostrand, H, Skiba, M, Skilton, R, Skvara, V, Slade, B, Smith, R, Smith, P, Smith, Sf, Snoj, L, Soare, S, Solano, Er, Somers, A, Sommariva, C, Sonato, P, Sos, M, Sousa, J, Sozzi, C, Spagnolo, S, Sparapani, P, Spelzini, T, Spineanu, F, Sprada, D, Sridhar, S, Stables, G, Stallard, J, Stamatelatos, I, Stamp, Mf, Stan-Sion, C, Stancar, Z, Staniec, P, Stankunas, G, Stano, M, Stavrou, C, Stefanikova, E, Stepanov, I, Stephen, Av, Stephen, M, Stephens, J, Stevens, B, Stober, J, Stokes, C, Strachan, J, Strand, P, Strauss, Hr, Strom, P, Studholme, W, Subba, F, Suchkov, E, Summers, Hp, Sun, H, Sutton, N, Svensson, J, Sytnykov, D, Szabolics, T, Szepesi, G, Suzuki, Tt, Tabares, F, Tadic, T, Tal, B, Tala, T, Taliercio, C, Tallargio, A, Tanaka, K, Tang, W, Tardocchi, M, Tatali, R, Taylor, D, Tegnered, D, Telesca, G, Teplova, N, Teplukhina, A, Terranova, D, Terry, C, Testa, D, Tholerus, E, Thomas, J, Thompson, Vk, Thornton, A, Tierens, W, Tiseanu, I, Tojo, H, Tokitani, M, Tolias, P, Tomes, M, Trimble, P, Tripsky, M, Tsalas, M, Tsavalas, P, Tskhakaya, D, Jun, Dt, Turner, I, Turner, Mm, Turnyanskiy, M, Tvalashvili, G, Tyshchenko, M, Uccello, A, Uljanovs, J, Urano, H, Urban, A, Urbanczyk, G, Uytdenhouwen, I, Vadgama, A, Valcarcel, D, Vale, R, Valentinuzzi, M, Valerii, K, Valisa, M, Olivares, Pv, Valovic, M, Van Eester, D, Van Renterghem, W, van Rooij, Gj, Varje, J, Vartanian, S, Vasava, K, Vasilopoulou, T, Vecsei, M, Vega, J, Ventre, S, Verdoolaege, G, Verona, C, Rinati, Gv, Veshchev, E, Vianello, N, Vicente, J, Viezzer, E, Villari, S, Villone, F, Vincent, M, Vincenzi, P, Vinyar, I, Viola, B, Vitins, A, Vizvary, Z, Vlad, M, Voitsekhovitch, I, Voltolina, D, von Toussaint, U, Vondracek, P, Vuksic, M, Wakeling, B, Waldon, C, Walkden, N, Walker, R, Walker, M, Walsh, M, Wang, N, Wang, E, Warder, S, Warren, R, Waterhouse, J, Watts, C, Wauters, T, Webb, M, Weckmann, A, Weiland, J, Weiland, M, Weisen, H, Weiszflog, M, Welch, P, West, A, Wheatley, M, Wheeler, S, Whitehead, Am, Whittaker, D, Widdowson, Am, Wiesen, S, Wilkie, G, Williams, J, Willoughby, D, Wilson, J, Wilson, I, Wilson, Hr, Wischmeier, M, Withycombe, A, Witts, D, Wolfrum, E, Wood, R, Woodley, R, Woodley, C, Wray, S, Wright, Jc, Wright, P, Wukitch, S, Wynn, A, Xiang, L, Xu, T, Xue, Y, Yadikin, D, Yakovenko, Y, Yanling, W, Yavorskij, V, Young, I, Young, R, Young, D, Zacks, J, Zagorski, R, Zaitsev, F, Zakharov, L, Zanino, R, Zarins, A, Zarins, R, Fernandez, Dz, Zastrow, Kd, Zerbini, M, Zhang, W, Zhou, Y, Zilli, E, Zocco, A, Zoita, V, Zoletnik, S, Zwingmann, W, Zychor, I, and JET Contributors
- Subjects
Physics ,Nuclear and High Energy Physics ,Fusion ,Jet (fluid) ,Maximum power principle ,Nuclear engineering ,Context (language use) ,Plasma ,Fusion power ,Condensed Matter Physics ,01 natural sciences ,7. Clean energy ,ICRH ,Charged particle ,010305 fluids & plasmas ,JET ,transport ,TRANSPORT ,Physics::Plasma Physics ,Beta (plasma physics) ,0103 physical sciences ,010306 general physics - Abstract
Predictability of burning plasmas is a key issue for designing and building credible future fusion devices. In this context, an important effort of physics understanding and guidance is being carried out in parallel to the on-going JET experimental campaigns in H, D and T by performing analyses and modelling towards an improvement of the understanding of DT physics for the optimization of the JET-DT neutron yield and fusion born alpha particle physics. Extrapolations to JET-DT from recent experiments using the maximum power available have been performed including some of the most sophisticated codes and a broad selection of models. There is a general agreement that 11-15MW of fusion power can be expected in DT for the hybrid and baseline scenarios. On the other hand, in high beta, torque and fast ion fraction conditions, isotope effects could be favourable leading to higher fusion yield. It is shown that alpha particles related physics, such as TAE destabilization or fusion power electron heating, could be studied in ITER relevant JET-DT plasmas.
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- 2019
8. The effectiveness of psychological skills training and behavioral interventions in sport using single-case designs: A meta regression analysis of the peer-reviewed studies
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Barker, JB, Slater, MJ, Pugh, G, Mellalieu, SD, McCarthy, PJ, Jones, MV, Moran, A, Barker, JB, Slater, MJ, Pugh, G, Mellalieu, SD, McCarthy, PJ, Jones, MV, and Moran, A
- Abstract
© 2020 We used a novel meta regression analysis approach principles to examine the effectiveness of psychological skills training and behavioral interventions in sport assessed using single-case experimental designs (SCEDs). One hundred and twenty-one papers met the inclusion criteria applied to eight database searches and key sport psychology journals. Seventy-one studies reported sufficient detail for effect sizes to be calculated for the effects of psychological skills training on psychological, behavioral, and performance variables. The unconditional mean effect size for weighted (Δ = 2.40) and unweighted (Δ = 2.83) models suggested large improvements in psychological, behavioral, and performance outcomes associated with implementing cognitive-behavioral psychological skills training and behavioral interventions with a SCED. However, meta-regression analysis revealed important heterogeneities and sources of bias within this literature. First, studies using a group-based approach reported lower effect sizes compared to studies using single-case approaches. Second, the single-case studies, (over 90 per cent the effect sizes), revealed upwardly biased effect sizes arising from: (i) positive publication bias such that studies using lower numbers of baseline observations reported larger effects, while studies using larger numbers of baseline observations reported smaller – but still substantial – effects; (ii) not adopting a multiple baseline design; and (iii) not establishing procedural reliability. We recommend that future researchers using SCED's should consider these methodological issues.
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- 2020
9. Managing trading errors: while every trader should create contingencies in his execution to avoid making errors, chances are at some point in time you will make a mistake and should have additional controls for dealing with them
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McCarthy, PJ
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Securities trading -- Forecasts and trends ,Securities law -- Evaluation ,Market trend/market analysis ,Business, general ,Business - Abstract
One of the first decisions a trader needs to make is whether to open a separate error account. While every effort should be made to have check and double-check entries [...]
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- 2012
10. Editorial: Mental health challenges in elite sport: Balancing risk with Reward
- Author
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MacIntyre, TE, Jones, M, Brewer, BW, Raalte, JV, O'Shea, D, McCarthy, PJ, MacIntyre, TE, Jones, M, Brewer, BW, Raalte, JV, O'Shea, D, and McCarthy, PJ
- Published
- 2017
11. Overview of ASDEX Upgrade results
- Author
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Aguiam, D, Aho-Mantila, L, Angioni, C, Arden, N, Parra, R, Asunta, O, Debaar, M, Balden, M, Behler, K, Bergmann, A, Bernardo, J, Bernert, M, Beurskens, M, Biancalani, A, Bilato, R, Birkenmeier, G, Bobkov, V, Bock, A, Bogomolov, A, Bolzonella, T, Boeswirth, B, Bottereau, C, Bottino, A, Van den Brand, H, Brezinsek, S, Brida, D, Brochard, F, Bruhn, C, Buchanan, J, Buhler, A, Burckhart, A, Cambon-Silva, D, Camenen, Y, Carvalho, P, Carrasco, G, Cazzaniga, C, Carr, M, Carralero, D, Casali, L, Castaldo, C, Cavedon, M, Challis, C, Chankin, A, Chapman, I, Clairet, F, Classen, I, Coda, S, Coelho, R, Coenen, J, Colas, L, Conway, G, Costea, S, Coster, D, Croci, G, Cseh, G, Czarnecka, A, D'Arcangelo, O, Day, C, Delogu, R, de Marne, P, Denk, S, Denner, P, Dibon, M, D'Inca, R, Disiena, A, Douai, D, Drenik, A, Drube, R, Dunne, M, Duval, B, Dux, R, Eich, T, Elgeti, S, Engelhardt, K, Erdos, B, Erofeev, I, Esposito, B, Fable, E, Faitsch, M, Fantz, U, Faugel, H, Felici, F, Fietz, S, Figueredo, A, Fischer, R, Ford, O, Frassinetti, L, Freethy, S, Froeschle, M, Fuchert, G, Fuchs, J, Fuenfgelder, H, Galazka, K, Galdon-Quiroga, J, Gallo, A, Gao, Y, Garavaglia, S, Garcia-Munoz, M, Geiger, B, Cianfarani, C, Giannone, L, Giovannozzi, E, Gleason-Gonzalez, C, Gloeggler, S, Gobbin, M, Goerler, T, Goodman, T, Gorini, G, Gradic, D, Graeter, A, Granucci, G, Greuner, H, Griener, M, Groth, M, Gude, A, Guenter, S, Guimarais, L, Haas, G, Hakola, A, Ham, C, Happel, T, Harrison, J, Hatch, D, Hauer, V, Hayward, T, Heinemann, B, Heinzel, S, Hellsten, T, Henderson, S, Hennequin, P, Herrmann, A, Heyn, E, Hitzler, F, Hobirk, J, Hoelzl, M, Hoeschen, T, Holm, J, Hopf, C, Hoppe, F, Horvath, L, Houben, A, Huber, A, Igochine, V, Ilkei, T, Ivanova-Stanik, I, Jacob, W, Jacobsen, A, Jacquot, J, Janky, F, Jardin, A, Jaulmes, F, Jenko, F, Jensen, T, Joffrin, E, Kaesemann, C, Kallenbach, A, Kalvin, S, Kantor, M, Kappatou, A, Kardaun, O, Karhunen, J, Kasilov, S, Kernbichler, W, Kim, D, Kimmig, S, Kirk, A, Klingshirn, H, Koch, F, Kocsis, G, Koehn, A, Kraus, M, Krieger, K, Krivska, A, Kraemr-Flecken, A, Kurki-Suonio, T, Kurzan, B, Lackner, K, Laggner, F, Lang, P, Lauber, P, Lazanyi, N, Lazaros, A, Lebschy, A, Li, L, Li, M, Liang, Y, Lipschultz, B, Liu, Y, Lohs, A, Luhmann, N, Lunt, T, Lyssoivan, A, Madsen, J, Maier, H, Maj, O, Mailloux, J, Maljaars, E, Manas, P, Mancini, A, Manhard, A, Manso, M, Mantica, P, Mantsinen, M, Manz, P, Maraschek, M, Martens, C, Martin, P, Marrelli, L, Martitsch, A, Mastrostefano, S, Mayer, A, Mayer, M, Mazon, D, Mccarthy, P, Mcdermott, R, Meisl, G, Meister, H, Medvedeva, A, Merkel, P, Merkel, R, Merle, A, Mertens, V, Meshcheriakov, D, Meyer, H, Meyer, O, Miettunen, J, Milanesio, D, Mink, F, Mlynek, A, Monaco, F, Moon, C, Nazikian, R, Nemes-Czopf, A, Neu, G, Neu, R, Nielsen, A, Nielsen, S, Nikolaeva, V, Nocente, M, Noterdaeme, J, Nowak, S, Oberkofler, M, Oberparleiter, M, Ochoukov, R, Odstrcil, T, Olsen, J, Orain, F, Palermo, F, Papp, G, Paradela Perez, I, Pautasso, G, Enzel, F, Petersson, P, Pinzon, J, Piovesan, P, Piron, C, Plaum, B, Ploeckl, B, Plyusnin, V, Pokol, G, Poli, E, Porte, L, Potzel, S, Prisiazhniuk, D, Puetterich, T, Ramisch, M, Rapson, C, Rasmussen, J, Raupp, G, Refy, D, Reich, M, Reimold, F, Ribeiro, T, Riedl, R, Rittich, D, Rocchi, G, Rodriguez-Ramos, M, Rohde, V, Ross, A, Rott, M, Rubel, M, Ryan, D, Ryter, F, Saarelma, S, Salewski, M, Salmi, A, Sanchis-Sanchez, L, Santos, G, Santos, J, Sauter, O, Scarabosio, A, Schall, G, Schmid, K, Schmitz, O, Schneider, P, Schneller, M, Schrittwieser, R, Schubert, M, Schwarz-Selinger, T, Schweinzer, J, Scott, B, Sehmer, T, Sertoli, M, Shabbir, A, Shalpegin, A, Shao, L, Sharapov, S, Siccinio, M, Sieglin, B, Sigalov, A, Silva, A, Silva, C, Simon, P, Simpson, J, Snicker, A, Sommariva, C, Sozzi, C, Spolaore, M, Stejner, M, Stober, J, Stobbe, F, Stroth, U, Strumberger, E, Suarez, G, Sugiyama, K, Sun, H, Suttrop, W, Szepesi, T, Tal, B, Tala, T, Tardini, G, Tardocchi, M, Terranova, D, Tierens, W, Told, D, Tudisco, O, Trevisan, G, Treutterer, W, Trier, E, Tripsky, M, Valisa, M, Valovic, M, Vanovac, B, Varela, P, Varoutis, S, Verdoolaege, G, Vezinet, D, Vianello, N, Vicente, J, Vierle, T, Viezzer, E, von Toussaint, U, Wagner, D, Wang, N, Wang, X, Weidl, M, Weil, White, A, Willensdorfer, M, Wiringer, B, Wischmeier, M, Wolf, R, Wolfrum, E, Xiang, L, Yang, Q, Yang, Z, Yu, Q, Zagorski, R, Zammuto, I, Zarzoso, D, Zhang, W, van Zeeland, M, Zehetbauer, T, Zilker, M, Zoletnik, S, Zohm, H, Parra, RArredondo, deBaar, M, Coenen, JW, Coster, DP, DiSiena, A, Duval, BP, Fuchs, JC, Hakola, AH, Holm, JH, Jacobsen, AS, Klingshirn, H-J, Lang, PT, Luhmann, NC, Manso, M-E, McCarthy, PJ, McDermott, R, Nielsen, AH, Nielsen, SK, Noterdaeme, J-M, Schneider, PA, Sun, H-J, White, AE, Zohm, H., Aguiam, D, Aho-Mantila, L, Angioni, C, Arden, N, Parra, R, Asunta, O, Debaar, M, Balden, M, Behler, K, Bergmann, A, Bernardo, J, Bernert, M, Beurskens, M, Biancalani, A, Bilato, R, Birkenmeier, G, Bobkov, V, Bock, A, Bogomolov, A, Bolzonella, T, Boeswirth, B, Bottereau, C, Bottino, A, Van den Brand, H, Brezinsek, S, Brida, D, Brochard, F, Bruhn, C, Buchanan, J, Buhler, A, Burckhart, A, Cambon-Silva, D, Camenen, Y, Carvalho, P, Carrasco, G, Cazzaniga, C, Carr, M, Carralero, D, Casali, L, Castaldo, C, Cavedon, M, Challis, C, Chankin, A, Chapman, I, Clairet, F, Classen, I, Coda, S, Coelho, R, Coenen, J, Colas, L, Conway, G, Costea, S, Coster, D, Croci, G, Cseh, G, Czarnecka, A, D'Arcangelo, O, Day, C, Delogu, R, de Marne, P, Denk, S, Denner, P, Dibon, M, D'Inca, R, Disiena, A, Douai, D, Drenik, A, Drube, R, Dunne, M, Duval, B, Dux, R, Eich, T, Elgeti, S, Engelhardt, K, Erdos, B, Erofeev, I, Esposito, B, Fable, E, Faitsch, M, Fantz, U, Faugel, H, Felici, F, Fietz, S, Figueredo, A, Fischer, R, Ford, O, Frassinetti, L, Freethy, S, Froeschle, M, Fuchert, G, Fuchs, J, Fuenfgelder, H, Galazka, K, Galdon-Quiroga, J, Gallo, A, Gao, Y, Garavaglia, S, Garcia-Munoz, M, Geiger, B, Cianfarani, C, Giannone, L, Giovannozzi, E, Gleason-Gonzalez, C, Gloeggler, S, Gobbin, M, Goerler, T, Goodman, T, Gorini, G, Gradic, D, Graeter, A, Granucci, G, Greuner, H, Griener, M, Groth, M, Gude, A, Guenter, S, Guimarais, L, Haas, G, Hakola, A, Ham, C, Happel, T, Harrison, J, Hatch, D, Hauer, V, Hayward, T, Heinemann, B, Heinzel, S, Hellsten, T, Henderson, S, Hennequin, P, Herrmann, A, Heyn, E, Hitzler, F, Hobirk, J, Hoelzl, M, Hoeschen, T, Holm, J, Hopf, C, Hoppe, F, Horvath, L, Houben, A, Huber, A, Igochine, V, Ilkei, T, Ivanova-Stanik, I, Jacob, W, Jacobsen, A, Jacquot, J, Janky, F, Jardin, A, Jaulmes, F, Jenko, F, Jensen, T, Joffrin, E, Kaesemann, C, Kallenbach, A, Kalvin, S, Kantor, M, Kappatou, A, Kardaun, O, Karhunen, J, Kasilov, S, Kernbichler, W, Kim, D, Kimmig, S, Kirk, A, Klingshirn, H, Koch, F, Kocsis, G, Koehn, A, Kraus, M, Krieger, K, Krivska, A, Kraemr-Flecken, A, Kurki-Suonio, T, Kurzan, B, Lackner, K, Laggner, F, Lang, P, Lauber, P, Lazanyi, N, Lazaros, A, Lebschy, A, Li, L, Li, M, Liang, Y, Lipschultz, B, Liu, Y, Lohs, A, Luhmann, N, Lunt, T, Lyssoivan, A, Madsen, J, Maier, H, Maj, O, Mailloux, J, Maljaars, E, Manas, P, Mancini, A, Manhard, A, Manso, M, Mantica, P, Mantsinen, M, Manz, P, Maraschek, M, Martens, C, Martin, P, Marrelli, L, Martitsch, A, Mastrostefano, S, Mayer, A, Mayer, M, Mazon, D, Mccarthy, P, Mcdermott, R, Meisl, G, Meister, H, Medvedeva, A, Merkel, P, Merkel, R, Merle, A, Mertens, V, Meshcheriakov, D, Meyer, H, Meyer, O, Miettunen, J, Milanesio, D, Mink, F, Mlynek, A, Monaco, F, Moon, C, Nazikian, R, Nemes-Czopf, A, Neu, G, Neu, R, Nielsen, A, Nielsen, S, Nikolaeva, V, Nocente, M, Noterdaeme, J, Nowak, S, Oberkofler, M, Oberparleiter, M, Ochoukov, R, Odstrcil, T, Olsen, J, Orain, F, Palermo, F, Papp, G, Paradela Perez, I, Pautasso, G, Enzel, F, Petersson, P, Pinzon, J, Piovesan, P, Piron, C, Plaum, B, Ploeckl, B, Plyusnin, V, Pokol, G, Poli, E, Porte, L, Potzel, S, Prisiazhniuk, D, Puetterich, T, Ramisch, M, Rapson, C, Rasmussen, J, Raupp, G, Refy, D, Reich, M, Reimold, F, Ribeiro, T, Riedl, R, Rittich, D, Rocchi, G, Rodriguez-Ramos, M, Rohde, V, Ross, A, Rott, M, Rubel, M, Ryan, D, Ryter, F, Saarelma, S, Salewski, M, Salmi, A, Sanchis-Sanchez, L, Santos, G, Santos, J, Sauter, O, Scarabosio, A, Schall, G, Schmid, K, Schmitz, O, Schneider, P, Schneller, M, Schrittwieser, R, Schubert, M, Schwarz-Selinger, T, Schweinzer, J, Scott, B, Sehmer, T, Sertoli, M, Shabbir, A, Shalpegin, A, Shao, L, Sharapov, S, Siccinio, M, Sieglin, B, Sigalov, A, Silva, A, Silva, C, Simon, P, Simpson, J, Snicker, A, Sommariva, C, Sozzi, C, Spolaore, M, Stejner, M, Stober, J, Stobbe, F, Stroth, U, Strumberger, E, Suarez, G, Sugiyama, K, Sun, H, Suttrop, W, Szepesi, T, Tal, B, Tala, T, Tardini, G, Tardocchi, M, Terranova, D, Tierens, W, Told, D, Tudisco, O, Trevisan, G, Treutterer, W, Trier, E, Tripsky, M, Valisa, M, Valovic, M, Vanovac, B, Varela, P, Varoutis, S, Verdoolaege, G, Vezinet, D, Vianello, N, Vicente, J, Vierle, T, Viezzer, E, von Toussaint, U, Wagner, D, Wang, N, Wang, X, Weidl, M, Weil, White, A, Willensdorfer, M, Wiringer, B, Wischmeier, M, Wolf, R, Wolfrum, E, Xiang, L, Yang, Q, Yang, Z, Yu, Q, Zagorski, R, Zammuto, I, Zarzoso, D, Zhang, W, van Zeeland, M, Zehetbauer, T, Zilker, M, Zoletnik, S, Zohm, H, Parra, RArredondo, deBaar, M, Coenen, JW, Coster, DP, DiSiena, A, Duval, BP, Fuchs, JC, Hakola, AH, Holm, JH, Jacobsen, AS, Klingshirn, H-J, Lang, PT, Luhmann, NC, Manso, M-E, McCarthy, PJ, McDermott, R, Nielsen, AH, Nielsen, SK, Noterdaeme, J-M, Schneider, PA, Sun, H-J, White, AE, and Zohm, H.
- Abstract
The ASDEX Upgrade (AUG) programme is directed towards physics input to critical elements of the ITER design and the preparation of ITER operation, as well as addressing physics issues for a future DEMO design. Since 2015, AUG is equipped with a new pair of 3-strap ICRF antennas, which were designed for a reduction of tungsten release during ICRF operation. As predicted, a factor two reduction on the ICRF-induced W plasma content could be achieved by the reduction of the sheath voltage at the antenna limiters via the compensation of the image currents of the central and side straps in the antenna frame. There are two main operational scenario lines in AUG. Experiments with low collisionality, which comprise current drive, ELM mitigation/suppression and fast ion physics, are mainly done with freshly boronized walls to reduce the tungsten influx at these high edge temperature conditions. Full ELM suppression and non-inductive operation up to a plasma current of MA could be obtained at low plasma density. Plasma exhaust is studied under conditions of high neutral divertor pressure and separatrix electron density, where a fresh boronization is not required. Substantial progress could be achieved for the understanding of the confinement degradation by strong D puffing and the improvement with nitrogen or carbon seeding. Inward/outward shifts of the electron density profile relative to the temperature profile effect the edge stability via the pressure profile changes and lead to improved/decreased pedestal performance. Seeding and D gas puffing are found to effect the core fueling via changes in a region of high density on the high field side (HFSHD). The integration of all above mentioned operational scenarios will be feasible and naturally obtained in a large device where the edge is more opaque for neutrals and higher plasma temperatures provide a lower collisionality. The combination of exhaust control with pellet fueling has been successfully demonstrated. High divert
- Published
- 2017
12. Developing major Sydney basin mines of the future
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Cost Effective Tunnelling in the Sydney Basin: AUCTA seminar (1988 : Sydney, N.S.W.) and McCarthy, PJ
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- 1988
13. Candels: The cosmic assembly near-infrared deep extragalactic legacy survey - The hubble space telescope observations, imaging data products, and mosaics
- Author
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Koekemoer, A, Faber, S, Ferguson, H, Grogin, N, Kocevski, D, Koo, D, Lai, K, Lotz, J, Lucas, R, Mcgrath, E, Ogaz, S, Rajan, A, Riess, A, Rodney, S, Strolger, L, Casertano, S, Castellano, M, Dahlen, T, Dickinson, M, Dolch, T, Fontana, A, Giavalisco, M, Grazian, A, Guo, Y, Hathi, N, Huang, K, van der Wel, A, Yan, H, Acquaviva, V, Alexander, D, Almaini, O, Ashby, M, Barden, M, Bell, E, Bournaud, F, Brown, T, Caputi, K, Cassata, P, Challis, P, Chary, R, Cheung, E, Cirasuolo, M, Conselice, C, Cooray, A, Croton, D, Daddi, E, Davé, R, de Mello, D, de Ravel, L, Dekel, A, Donley, J, Dunlop, J, Dutton, A, Elbaz, D, Fazio, G, Filippenko, A, Finkelstein, S, Frazer, C, Gardner, J, Garnavich, P, Gawiser, E, Gruetzbauch, R, Hartley, W, Häussler, B, Herrington, J, Hopkins, P, Huang, J, Jha, S, Johnson, A, Kartaltepe, J, Khostovan, A, Kirshner, R, Lani, C, Lee, K, Li, W, Madau, P, Mccarthy, P, Mcintosh, D, Mclure, R, Mcpartland, C, Mobasher, B, Moreira, H, Mortlock, A, Moustakas, L, Mozena, M, Nandra, K, Newman, J, Nielsen, J, Niemi, S, Noeske, K, Papovich, C, Pentericci, L, Pope, A, Primack, J, Ravindranath, S, Reddy, N, Renzini, A, Rix, H, Robaina, A, Rosario, D, Rosati, P, Salimbeni, S, Scarlata, C, Siana, B, Simard, L, Smidt, J, Snyder, D, Somerville, R, Spinrad, H, Straughn, A, Telford, O, Teplitz, H, Trump, J, Vargas, C, Villforth, C, Wagner, C, Wandro, P, Wechsler, R, Weiner, B, Wiklind, T, Wild, V, Wilson, G, Wuyts, S, Yun, M, Koekemoer, AM, Faber, SM, Ferguson, HC, Grogin, NA, Kocevski, DD, Koo, DC, Lotz, JM, Lucas, RA, McGrath, EJ, Riess, AG, Rodney, SA, Guo, YC, Hathi, NP, Huang, KH, Yan, HJ, Alexander, DM, Ashby, MLN, Bell, EF, Brown, TM, Caputi, KI, Challis, PJ, Chary, RR, Conselice, CJ, Cooray, AR, Croton, DJ, de Mello, DF, Donley, JL, Dunlop, JS, Dutton, AA, Fazio, GG, Filippenko, AV, Finkelstein, SL, Gardner, JP, Garnavich, PM, Hartley, WG, Hopkins, PF, Huang, JS, Jha, SW, Kartaltepe, JS, Khostovan, AA, Kirshner, RP, Lee, KS, Li, WD, McCarthy, PJ, McIntosh, DH, McLure, RJ, McPartland, C, Moustakas, LA, Newman, JA, Nielsen, JL, Noeske, KG, Papovich, CJ, Primack, JR, Reddy, NA, Rix, HW, Robaina, AR, Rosario, DJ, Somerville, RS, Straughn, AN, Teplitz, HI, Trump, JR, Wagner, CR, Wechsler, RH, Weiner, BJ, Yun, MS, Koekemoer, A, Faber, S, Ferguson, H, Grogin, N, Kocevski, D, Koo, D, Lai, K, Lotz, J, Lucas, R, Mcgrath, E, Ogaz, S, Rajan, A, Riess, A, Rodney, S, Strolger, L, Casertano, S, Castellano, M, Dahlen, T, Dickinson, M, Dolch, T, Fontana, A, Giavalisco, M, Grazian, A, Guo, Y, Hathi, N, Huang, K, van der Wel, A, Yan, H, Acquaviva, V, Alexander, D, Almaini, O, Ashby, M, Barden, M, Bell, E, Bournaud, F, Brown, T, Caputi, K, Cassata, P, Challis, P, Chary, R, Cheung, E, Cirasuolo, M, Conselice, C, Cooray, A, Croton, D, Daddi, E, Davé, R, de Mello, D, de Ravel, L, Dekel, A, Donley, J, Dunlop, J, Dutton, A, Elbaz, D, Fazio, G, Filippenko, A, Finkelstein, S, Frazer, C, Gardner, J, Garnavich, P, Gawiser, E, Gruetzbauch, R, Hartley, W, Häussler, B, Herrington, J, Hopkins, P, Huang, J, Jha, S, Johnson, A, Kartaltepe, J, Khostovan, A, Kirshner, R, Lani, C, Lee, K, Li, W, Madau, P, Mccarthy, P, Mcintosh, D, Mclure, R, Mcpartland, C, Mobasher, B, Moreira, H, Mortlock, A, Moustakas, L, Mozena, M, Nandra, K, Newman, J, Nielsen, J, Niemi, S, Noeske, K, Papovich, C, Pentericci, L, Pope, A, Primack, J, Ravindranath, S, Reddy, N, Renzini, A, Rix, H, Robaina, A, Rosario, D, Rosati, P, Salimbeni, S, Scarlata, C, Siana, B, Simard, L, Smidt, J, Snyder, D, Somerville, R, Spinrad, H, Straughn, A, Telford, O, Teplitz, H, Trump, J, Vargas, C, Villforth, C, Wagner, C, Wandro, P, Wechsler, R, Weiner, B, Wiklind, T, Wild, V, Wilson, G, Wuyts, S, Yun, M, Koekemoer, AM, Faber, SM, Ferguson, HC, Grogin, NA, Kocevski, DD, Koo, DC, Lotz, JM, Lucas, RA, McGrath, EJ, Riess, AG, Rodney, SA, Guo, YC, Hathi, NP, Huang, KH, Yan, HJ, Alexander, DM, Ashby, MLN, Bell, EF, Brown, TM, Caputi, KI, Challis, PJ, Chary, RR, Conselice, CJ, Cooray, AR, Croton, DJ, de Mello, DF, Donley, JL, Dunlop, JS, Dutton, AA, Fazio, GG, Filippenko, AV, Finkelstein, SL, Gardner, JP, Garnavich, PM, Hartley, WG, Hopkins, PF, Huang, JS, Jha, SW, Kartaltepe, JS, Khostovan, AA, Kirshner, RP, Lee, KS, Li, WD, McCarthy, PJ, McIntosh, DH, McLure, RJ, McPartland, C, Moustakas, LA, Newman, JA, Nielsen, JL, Noeske, KG, Papovich, CJ, Primack, JR, Reddy, NA, Rix, HW, Robaina, AR, Rosario, DJ, Somerville, RS, Straughn, AN, Teplitz, HI, Trump, JR, Wagner, CR, Wechsler, RH, Weiner, BJ, and Yun, MS
- Abstract
This paper describes the Hubble Space Telescope imaging data products and data reduction procedures for the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS). This survey is designed to document the evolution of galaxies and black holes at z ≈ 1.5-8, and to study Type Ia supernovae at z > 1.5. Five premier multi-wavelength sky regions are selected, each with extensive multi-wavelength observations. The primary CANDELS data consist of imaging obtained in the Wide Field Camera 3 infrared channel (WFC3/IR) and the WFC3 ultraviolet/optical channel, along with the Advanced Camera for Surveys (ACS). The CANDELS/Deep survey covers ∼ 125 arcmin 2 within GOODS-N and GOODS-S, while the remainder consists of the CANDELS/Wide survey, achieving a total of ∼ 800 arcmin2 across GOODS and three additional fields (Extended Groth Strip, COSMOS, and Ultra-Deep Survey). We summarize the observational aspects of the survey as motivated by the scientific goals and present a detailed description of the data reduction procedures and products from the survey. Our data reduction methods utilize the most up-to-date calibration files and image combination procedures. We have paid special attention to correcting a range of instrumental effects, including charge transfer efficiency degradation for ACS, removal of electronic bias-striping present in ACS data after Servicing Mission 4, and persistence effects and other artifacts in WFC3/IR. For each field, we release mosaics for individual epochs and eventual mosaics containing data from all epochs combined, to facilitate photometric variability studies and the deepest possible photometry. A more detailed overview of the science goals and observational design of the survey are presented in a companion paper.
- Published
- 2011
14. Associated bacterial communities of two deep-water sponges
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Olson, JB, primary and McCarthy, PJ, additional
- Published
- 2005
- Full Text
- View/download PDF
15. The case for Anaerobic Digestion.
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McCarthy, PJ
- Subjects
ANAEROBIC digestion - Published
- 2021
16. Adaptive learning for disruption prediction in non-stationary conditions
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Murari, A., Lungaroni, M., Gelfusa, M., Peluso, E., Vega, J., Abduallev, S., Abhangi, M., Abreu, P., Afanasev, V, Afzal, M., Aggarwal, K. M., Ahlgren, T., Aho-Mantila, L., Aiba, N., Airila, M., Alarcon, T., Albanese, R., Alegre, D., Aleiferis, S., Alessi, E., Aleynikov, P., Alkseev, A., Allinson, M., Alper, B., Alves, E., Ambrosino, G., Ambrosino, R., Amosov, V, Sunden, E. Andersson, Andrews, R., Angelone, M., Anghel, M., Angioni, C., Appel, L., Appelbee, C., Arena, P., Ariola, M., Arshad, S., Artaud, J., Arter, W., Ash, A., Ashikawa, N., Aslanyan, V, Asunta, O., Asztalos, O., Auriemma, F., Austin, Y., Avotina, L., Axton, M., Ayres, C., Baciero, A., Baiao, D., Balboa, I, Balden, M., Balshaw, N., Bandaru, V. K., Banks, J., Baranov, Y. F., Barcellona, C., Barnard, T., Barnes, M., Barnsley, R., Wiechec, A. Baron, Orte, L. Barrera, Baruzzo, M., Basiuk, V, Bassan, M., Bastow, R., Batista, A., Batistoni, P., Baumane, L., Bauvir, B., Baylor, L., Beaumont, P. S., Beckers, M., Beckett, B., Bekris, N., Beldishevski, M., Bell, K., Belli, F., Belonohy, E., Benayas, J., Bergsaker, H., Bernardo, J., Bernert, M., Berry, M., Bertalot, L., Besiliu, C., Betar, H., Beurskens, M., Bielecki, J., Biewer, T., Bilato, R., Biletskyi, O., Bilkova, P., Binda, F., Birkenmeier, G., Bizarro, J. P. S., Bjorkas, C., Blackburn, J., Blackman, T. R., Blanchard, P., Blatchford, P., Bobkov, V, Boboc, A., Bogar, O., Bohm, P., Bohm, T., Bolshakova, I, Bolzonella, T., Bonanomi, N., Boncagni, L., Bonfiglio, D., Bonnin, X., Boom, J., Borba, D., Borodin, D., Borodkina, I, Boulbe, C., Bourdelle, C., Bowden, M., Bowman, C., Boyce, T., Boyer, H., Bradnam, S. C., Braic, V, Bravanec, R., Breizman, B., Brennan, D., Breton, S., Brett, A., Brezinsek, S., Bright, M., Brix, M., Broeckx, W., Brombin, M., Broslawski, A., Brown, B., Brunetti, D., Bruno, E., Buch, J., Buchanan, J., Buckingham, R., Buckley, M., Bucolo, M., Budny, R., Bufferand, H., Buller, S., Bunting, P., Buratti, P., Burckhart, A., Burroughes, G., Buscarino, A., Busse, A., Butcher, D., Butler, B., Bykov, I, Cahyna, P., Calabro, G., Calacci, L., Callaghan, D., Callaghan, J., Calvo, I, Camenen, Y., Camp, P., Campling, D. C., Cannas, B., Capat, A., Carcangiu, S., Card, P., Cardinali, A., Carman, P., Carnevale, D., Carr, M., Carralero, D., Carraro, L., Carvalho, B. B., Carvalho, I, Carvalho, P., Carvalho, D. D., Casson, F. J., Castaldo, C., Catarino, N., Causa, F., Cavazzana, R., Cave-Ayland, K., Cavedon, M., Cecconello, M., Ceccuzzi, S., Cecil, E., Challis, C. D., Chandra, D., Chang, C. S., Chankin, A., Chapman, I. T., Chapman, B., Chapman, S. C., Chernyshova, M., Chiariello, A., Chitarin, G., Chmielewski, P., Chone, L., Ciraolo, G., Ciric, D., Citrin, J., Clairet, F., Clark, M., Clark, E., Clarkson, R., Clay, R., Clements, C., Coad, J. P., Coates, P., Cobalt, A., Coccorese, V, Cocilovo, V, Coelho, R., Coenen, J. W., Coffey, I, Colas, L., Colling, B., Collins, S., Conka, D., Conroy, S., Conway, N., Coombs, D., Cooper, S. R., Corradino, C., Corre, Y., Corrigan, G., Coster, D., Craciunescu, T., Cramp, S., Crapper, C., Crisanti, F., Croci, G., Croft, D., Crombe, K., Cruz, N., Cseh, G., Cufar, A., Cullen, A., Curson, P., Curuia, M., Czarnecka, A., Czarski, T., Cziegler, I, Dabirikhah, H., Dal Molin, A., Dalgliesh, P., Dalley, S., Dankowski, J., Darrow, D., David, P., Davies, A., Davis, W., Dawson, K., Day, I, Day, C., De Bock, M., de Castro, A., De Dominici, G., de la Cal, E., de la Luna, E., De Masi, G., De Temmerman, G., De Tommasi, G., de Vries, P., Deane, J., Dejarnac, R., Del Sarto, D., Delabie, E., Demerdzhiev, V, Dempsey, A., den Harder, N., Dendy, R. O., Denis, J., Denner, P., Devaux, S., Devynck, P., Di Maio, F., Di Siena, A., Di Troia, C., Dickinson, D., Dinca, P., Dittmar, T., Dobrashian, J., Doerk, H., Doerner, R. P., Domptail, F., Donne, T., Dorling, S. E., Douai, D., Dowson, S., Drenik, A., Dreval, M., Drewelow, P., Drews, P., Duckworth, Ph, Dumont, R., Dumortier, P., Dunai, D., Dunne, M., Duran, I, Durodie, F., Dutta, P., Duval, B. P., Dux, R., Dylst, K., Edappala, P., V, Edwards, A. M., Edwards, J. S., Eich, Th, Eidietis, N., Eksaeva, A., Ellis, R., Ellwood, G., Elsmore, C., Emery, S., Enachescu, M., Ericsson, G., Eriksson, J., Eriksson, F., Eriksson, L. G., Ertmer, S., Esquembri, S., Esquisabel, A. L., Esser, H. G., Ewart, G., Fable, E., Fagan, D., Faitsch, M., Falie, D., Fanni, A., Farahani, A., Fasoli, A., Faugeras, B., Fazinic, S., Felici, F., Felton, R. C., Feng, S., Fernades, A., Fernandes, H., Ferreira, J., Ferreira, D. R., Ferro, G., Fessey, J. A., Ficker, O., Field, A., Fietz, S., Figini, L., Figueiredo, J., Figueiredo, A., Fil, N., Finburg, P., Fischer, U., Fittill, L., Fitzgerald, M., Flammini, D., Flanagan, J., Flinders, K., Foley, S., Fonnesu, N., Fontdecaba, J. M., Formisano, A., Forsythe, L., Fortuna, L., Fransson, E., Frasca, M., Frassinetti, L., Freisinger, M., Fresa, R., Fridstrom, R., Frigione, D., Fuchs, V, Fusco, V, Futatani, S., Gal, K., Galassi, D., Galazka, K., Galeani, S., Gallart, D., Galvao, R., Gao, Y., Garcia, J., Garcia-Carrasco, A., Garcia-Munoz, M., Gardener, M., Garzotti, L., Gaspar, J., Gaudio, P., Gear, D., Gebhart, T., Gee, S., Geiger, B., George, R., Gerasimov, S., Gervasini, G., Gethins, M., Ghani, Z., Ghate, M., Gherendi, M., Ghezzi, F., Giacalone, J. C., Giacomelli, L., Giacometti, G., Gibson, K., Giegerich, T., Gil, L., Gilbert, M. R., Gin, D., Giovannozzi, E., Giroud, C., Gloeggler, S., Goff, J., Gohil, P., Goloborod'Ko, V, Gomes, R., Goncalves, B., Goniche, M., Goodyear, A., Gorini, G., Goerler, T., Goulding, R., Goussarov, A., Graham, B., Graves, J. P., Greuner, H., Grierson, B., Griffiths, J., Griph, S., Grist, D., Groth, M., Grove, R., Gruca, M., Guard, D., Guerard, C., Guillemaut, C., Guirlet, R., Gulati, S., Gurl, C., Gutierrez-Milla, A., Utoh, H. H., Hackett, L., Hacquin, S., Hager, R., Hakola, A., Halitovs, M., Hall, S., Hallworth-Cook, S., Ham, C., Hamed, M., Hamilton, N., Hamlyn-Harris, C., Hammond, K., Hancu, G., Harrison, J., Harting, D., Hasenbeck, F., Hatano, Y., Hatch, D. R., Haupt, T., Hawes, J., Hawkes, N. C., Hawkins, J., Hawkins, P., Hazel, S., Heesterman, P., Heinola, K., Hellesen, C., Hellsten, T., Helou, W., Hemming, O., Hender, T. C., Henderson, S. S., Henderson, M., Henriques, R., Hepple, D., Herfindal, J., Hermon, G., Hidalgo, C., Higginson, W., Highcock, E. G., Hillesheim, J., Hillis, D., Hizanidis, K., Hjalmarsson, A., Ho, A., Hobirk, J., Hogben, C. H. A., Hogeweij, G. M. D., Hollingsworth, A., Hollis, S., Hoelzl, M., Honore, J-J, Hook, M., Hopley, D., Horacek, J., Hornung, G., Horton, A., Horton, L. 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- Subjects
Nuclear and High Energy Physics ,Computer science ,ensembles of classifiers ,Machine learning ,computer.software_genre ,disruptions ,01 natural sciences ,010305 fluids & plasmas ,obsolescence ,Ensembles of classifiers ,Stationary conditions ,0103 physical sciences ,010306 general physics ,de-learning ,Jet (fluid) ,business.industry ,machine learning predictors ,adaptive training ,JET ,Settore ING-IND/18 - Fisica dei Reattori Nucleari ,machine learning predictor ,Condensed Matter Physics ,disruption ,Obsolescence ,Artificial intelligence ,Adaptive learning ,business ,computer - Abstract
For many years, machine learning tools have proved to be very powerful disruption predictors in tokamaks. On the other hand, the vast majority of the techniques deployed assume that the input data is independent and is sampled from exactly the same probability distribution for the training set, the test set and the final real time deployment. This hypothesis is certainly not verified in practice, since the experimental programmes evolve quite rapidly, resulting typically in ageing of the predictors and consequent suboptimal performance. This paper describes various adaptive training strategies that have been tested to maintain the performance of disruption predictors in non- stationary conditions. The proposed approaches have been implemented using new ensembles of classifiers, explicitly developed for the present application. The improvements in performance are unquestionable and, given the difficulties encountered so far in translating predictors from one device to another, the proposed adaptive methods from scratch can therefore be considered a useful option in the arsenal of alternatives envisaged for the next generation of devices, particularly at the very beginning of their operation.
- Published
- 2019
17. Role of fast ion pressure in the isotope effect in JET L-mode plasmas
- Author
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P., Greuner, H., Grierson, B., Griffiths, J., Griph, S., Grist, D., Groth, M., Grove, R., Gruca, M., Guard, D., Guerard, C., Guillemaut, C., Guirlet, R., Gulati, S., Gurl, C., Gutierrez-Milla, A., Utoh, H. H., Hackett, L., Hacquin, S., Hager, R., Hakola, A., Halitovs, M., Hall, S., Hallworth-Cook, S., Ham, C., Hamed, M., Hamilton, N., Hamlyn-Harris, C., Hammond, K., Hancu, G., Harrison, J., Harting, D., Hasenbeck, F., Hatano, Y., Hatch, D. R., Haupt, T., Hawes, J., Hawkes, N. C., Hawkins, J., Hawkins, P., Hazel, S., Heesterman, P., Heinola, K., Hellesen, C., Hellsten, T., Helou, W., Hemming, O., Hender, T. C., Henderson, S. S., Henderson, M., Henriques, R., Hepple, D., Herfindal, J., Hermon, G., Hidalgo, C., Higginson, W., Highcock, E. G., Hillesheim, J., Hillis, D., Hizanidis, K., Hjalmarsson, A., Ho, A., Hobirk, J., Hogben, C. H. A., Hogeweij, G. M. D., Hollingsworth, A., Hollis, S., Hoelzl, M., Honore, J-J, Hook, M., Hopley, D., Horacek, J., Hornung, G., Horton, A., Horton, L. D., Horvath, L., Hotchin, S. P., Howell, R., Hubbard, A., Huber, A., Huber, V, Huddleston, T. M., Hughes, M., Hughes, J., Huijsmans, G. T. A., Huynh, P., Hynes, A., Igaune, I., Iglesias, D., Imazawa, N., Imrisek, M., Incelli, M., Innocente, P., Ivanova-Stanik, I., Ivings, E., Jachmich, S., Jackson, A., Jackson, T., Jacquet, P., Jansons, J., Jaulmes, F., Jednorog, S., Jenkins, I, Jepu, I, Johnson, T., Johnson, R., Johnston, J., Joita, L., Joly, J., Jonasson, E., Jones, T., Jones, C., Jones, L., Jones, G., Jones, N., Juvonen, M., Hoshino, K. K., Kallenbach, A., Kalsey, M., Kaltiaisenaho, T., Kamiya, K., Kaniewski, J., Kantor, A., Kappatou, A., Karhunen, J., Karkinsky, D., Kaufman, M., Kaveney, G., Kazakov, Y., Kazantzidis, V, Keeling, D. L., Keenan, F. P., Kempenaars, M., Kent, O., Kent, J., Keogh, K., Khilkevich, E., Kim, H-T, Kim, H. T., King, R., King, D., Kinna, D. 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Zanino, R, Zarins, A, Zarins, R, Fernandez, Dz, Zastrow, Kd, Zerbini, M, Zhang, W, Zhou, Y, Zilli, E, Zocco, A, Zoita, V, Zoletnik, S, Zwingmann, W, Zychor, I, Department of Physics, and Materials Physics
- Subjects
Nuclear and High Energy Physics ,Materials science ,Hydrogen ,chemistry.chemical_element ,114 Physical sciences ,7. Clean energy ,01 natural sciences ,010305 fluids & plasmas ,Ion ,gyrokinetic ,JET tokamak ,Physics::Plasma Physics ,equations ,turbulent transport ,fast ions ,isotope effect ,gyrokinetic simulations ,0103 physical sciences ,Kinetic isotope effect ,drift orbit width ,fast ion ,Physics::Atomic Physics ,Nuclear Experiment ,010306 general physics ,Jet (fluid) ,Stable isotope ratio ,turbulence ,Plasma ,gyrokinetic simulation ,Condensed Matter Physics ,chemistry ,Deuterium ,confinement ,transport ,Physics::Space Physics ,simulations ,Atomic physics ,DRIFT ORBIT WIDTH ,CONFINEMENT ,SIMULATIONS ,TURBULENCE ,TRANSPORT ,EQUATIONS ,Ion cyclotron resonance - Abstract
This paper presents results of JET ITER-like wall L-mode experiments in hydrogen and deuterium (D) plasmas, dedicated to the study of the isotope dependence of ion heat transport by determination of the ion critical gradient and stiffness by varying the ion cyclotron resonance heating power deposition. When no strong role of fast ions in the plasma core is expected, the main difference between the two isotope plasmas is determined by the plasma edge and the core behavior is consistent with a gyro-Bohm scaling. When the heating power (and the fast ion pressure) is increased, in addition to the difference in the edge region, also the plasma core shows substantial changes. The stabilization of ion heat transport by fast ions, clearly visible in D plasmas, appears to be weaker in H plasmas, resulting in a higher ion heat flux in H with apparent anti-gyro-Bohm mass scaling. The difference is found to be caused by the different fast ion pressure between H and D plasmas, related to the heating power settings and to the different fast ion slowing down time, and is completely accounted for in non-linear gyrokinetic simulations. The application of the TGLF quasi-linear model to this set of data is also discussed.
- Published
- 2019
18. Ion cyclotron resonance heating scenarios for DEMO
- Author
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Nuclear and High Energy Physics ,Tokamak ,Materials science ,heating ,Sawtooth wave ,wave ,discharges ,114 Physical sciences ,7. Clean energy ,01 natural sciences ,010305 fluids & plasmas ,law.invention ,law ,Physics::Plasma Physics ,0103 physical sciences ,Dielectric heating ,icrh ,010306 general physics ,tokamak ,mode conversion ,iter ,minority ,Plasma ,Condensed Matter Physics ,plasmas ,Computational physics ,ICRH ,ITER ,current drive ,Ion cyclotron resonance heating ,sawtooth ,oscillations ,systems code - Abstract
The present paper offers an overview of the potential of ion cyclotron resonance heating (ICRH) or radio frequency heating for the DEMO machine. It is found that various suitable heating schemes are available. Similar to ITER and in view of the limited bandwidth of about 10 MHz that can be achieved to ensure optimal functioning of the launcher, it is proposed to make core second harmonic tritium heating the key ion heating scheme, assisted by fundamental cyclotron heating He-3 in the early phase of the discharge; for the present design of DEMO-with a static magnetic field strength of B-o = 5.855 T-that places the T and 3He layers in the core for f = 60 MHz and suggests centering the bandwidth around that main operating frequency. In line with earlier studies for hot, dense plasmas in large-size magnetic confinement machines, it is shown that good single pass absorption is achieved but that the size as well as the operating density and temperature of the machine cause the electrons to absorb a non-negligible fraction of the power away from the core when core ion heating is aimed at. Current drive and alternative heating options are briefly discussed and a dedicated computation is done for the traveling wave antenna, proposed for DEMO in view of its compatibility with substantial antenna-plasma distances. The various tasks that ICRH can fulfill are briefly listed. Finally, the impact of transport and the sensitivity of the obtained results to changes in the machine parameters is commented on.
19. A new mechanism for increasing density peaking in tokamaks: improvement of the inward particle pinch with edge E x B shearing
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L, Colling, B, Collins, S, Conka, D, Conroy, S, Conway, N, Coombs, D, Cooper, Sr, Corradino, C, Corre, Y, Corrigan, G, Coster, D, Craciunescu, T, Cramp, S, Crapper, C, Crisanti, F, Croci, G, Croft, D, Crombe, K, Cruz, N, Cseh, G, Cufar, A, Cullen, A, Curson, P, Curuia, M, Czarnecka, A, Czarski, T, Cziegler, I, Dabirikhah, H, Dal Molin, A, Dalgliesh, P, Dalley, S, Dankowski, J, Darrow, D, David, P, Davies, A, Davis, W, Dawson, K, Day, I, Day, C, De Bock, M, de Castro, A, De Dominici, G, de la Cal, E, de la Luna, E, De Masi, G, De Temmerman, G, De Tommasi, G, de Vries, P, Deane, J, Dejarnac, R, Del Sarto, D, Delabie, E, Demerdzhiev, V, Dempsey, A, den Harder, N, Dendy, Ro, Denis, J, Denner, P, Devaux, S, Devynck, P, Di Maio, F, Di Siena, A, Di Troia, C, Dickinson, D, Dinca, P, Dittmar, T, Dobrashian, J, Doerner, Rp, Domptail, F, Donne, T, Dorling, Se, Douai, D, Dowson, S, Drenik, A, Dreval, M, Drewelow, P, Drews, P, Duckworth, P, Dumont, R, Dumortier, P, Dunai, D, Dunne, M, Duran, I, Durodie, F, Dutta, P, Duval, Bp, Dux, R, Dylst, K, Edappala, Pv, Edwards, Am, Edwards, J, Eich, T, Eidietis, N, Eksaeva, A, Ellis, R, Ellwood, G, Elsmore, C, Emery, S, Enachescu, M, Ericsson, G, Eriksson, J, Eriksson, F, Eriksson, Lg, Ertmer, S, Esquembri, S, Esquisabel, Al, Esser, Hg, Ewart, G, Fable, E, Fagan, D, Faitsch, M, Falie, D, Fanni, A, Farahani, A, Fasoli, A, Faugeras, B, Fazinic, S, Felici, F, Felton, Rc, Feng, S, Fernades, A, Fernandes, H, Ferreira, J, Ferreira, Dr, Ferro, G, Fessey, Ja, Ficker, O, Field, A, Fietz, S, Figini, L, Figueiredo, J, Figueiredo, A, Fil, N, Finburg, P, Fischer, U, Fittill, L, Fitzgerald, M, Flammini, D, Flanagan, J, Flinders, K, Foley, S, Fonnesu, N, Fontdecaba, Jm, Formisano, A, Forsythe, L, Fortuna, L, Fransson, E, Frasca, M, Frassinetti, L, Freisinger, M, Fresa, R, Fridstrom, R, Frigione, D, Fuchs, V, Fusco, V, Futatani, S, Gal, K, Galassi, D, Galazka, K, Galeani, S, Gallart, D, Galvao, R, Gao, Y, Garcia-Carrasco, A, Garcia-Munoz, M, Gardener, M, Garzotti, L, Gaspar, J, Gaudio, P, Gear, D, Gebhart, T, Gee, S, Geiger, B, Gelfusa, M, George, R, Gerasimov, S, Gervasini, G, Gethins, M, Ghani, Z, Ghate, M, Gherendi, M, Ghezzi, F, Giacalone, Jc, Giacomelli, L, Giacometti, G, Gibson, K, Giegerich, T, Gil, L, Gilbert, Mr, Gin, D, Giovannozzi, E, Giroud, C, Gloggler, S, Goff, J, Gohil, P, Goloborod'Ko, V, Gomes, R, Goncalves, B, Goniche, M, Goodyear, A, Gorini, G, Goulding, R, Goussarov, A, Graham, B, Graves, Jp, Greuner, H, Grierson, B, Griffiths, J, Griph, S, Grist, D, Groth, M, Grove, R, Gruca, M, Guard, D, Guerard, C, Guillemaut, C, Guirlet, R, Gulati, S, Gurl, C, Gutierrez-Milla, A, Utoh, Hh, Hackett, L, Hacquin, S, Hager, R, Hakola, A, Halitovs, M, Hall, S, Hallworth-Cook, S, Ham, C, Hamed, M, Hamilton, N, Hamlyn-Harris, C, Hammond, K, Hancu, G, Harrison, J, Harting, D, Hasenbeck, F, Hatano, Y, Hatch, Dr, Haupt, T, Hawes, J, Hawkes, Nc, Hawkins, J, Hawkins, P, Hazel, S, Heesterman, P, Heinola, K, Hellesen, C, Hellsten, T, Helou, W, Hemming, O, Hender, Tc, Henderson, S, Henderson, M, Henriques, R, Hepple, D, Herfindal, J, Hermon, G, Hidalgo, C, Higginson, W, Highcock, Eg, Hillesheim, J, Hillis, D, Hizanidis, K, Hjalmarsson, A, Ho, A, Hobirk, J, Hogben, Cha, Hogeweij, Gmd, Hollingsworth, A, Hollis, S, Holzl, M, Honore, Jj, Hook, M, Hopley, D, Horacek, J, Hornung, G, Horton, A, Horton, Ld, Horvath, L, Hotchin, Sp, Howell, R, Hubbard, A, Huber, A, Huber, V, Huddleston, Tm, Hughes, M, Hughes, J, Huijsmans, Gta, Huynh, P, Hynes, A, Igaune, I, Iglesias, D, Imazawa, N, Imrisek, M, Incelli, M, Innocente, P, Ivanova-Stanik, I, Ivings, E, Jachmich, S, Jackson, A, Jackson, T, Jacquet, P, Jansons, J, Jaulmes, F, Jednorog, S, Jenkins, I, Jepu, I, Johnson, T, Johnson, R, Johnston, J, Joita, L, Joly, J, Jonasson, E, Jones, T, Jones, C, Jones, L, Jones, G, Jones, N, Juvonen, M, Hoshino, Kk, Kallenbach, A, Kalsey, M, Kaltiaisenaho, T, Kamiya, K, Kaniewski, J, Kantor, A, Kappatou, A, Karhunen, J, Karkinsky, D, Kaufman, M, Kaveney, G, Kazakov, Y, Kazantzidis, V, Keeling, Dl, Keenan, Fp, Kempenaars, M, Kent, O, Kent, J, Keogh, K, Khilkevich, E, Kim, Ht, King, R, King, D, Kinna, Dj, Kiptily, V, Kirk, A, Kirov, K, Kirschner, A, Kizane, G, Klas, M, Klepper, C, Klix, A, Knight, M, Knight, P, Knipe, S, Knott, S, Kobuchi, T, Kochl, F, Kocsis, G, Kodeli, I, Koechl, F, Kogut, D, Koivuranta, S, Kolesnichenko, Y, Kollo, Z, Kominis, Y, Koppen, M, Korolczuk, S, Kos, B, Koslowski, Hr, Kotschenreuther, M, Koubiti, M, Kovaldins, R, Kovanda, O, Kowalska-Strzeciwilk, E, Krasilnikov, A, Krasilnikov, V, Krawczyk, N, Kresina, M, Krieger, K, Krivska, A, Kruezi, U, Ksiazek, I, Kukushkin, A, Kundu, A, Kurki-Suonio, T, Kwak, S, Kwon, Oj, Laguardia, L, Lahtinen, A, Laing, A, Lalousis, P, Lam, N, Lamb, C, Lambertz, Ht, Lang, Pt, Lanthaler, S, Neto, El, Laszynska, E, Lawless, R, Lawson, Kd, Lazaros, A, Lazzaro, E, Leach, R, Learoyd, G, Leerink, S, Lefebvre, X, Leggate, Hj, Lehmann, J, Lehnen, M, Leichauer, P, Leichtle, D, Leipold, F, Lengar, I, Lennholm, M, Lepiavko, B, Leppanen, J, Lerche, E, Lescinskis, A, Lescinskis, B, Lesnoj, S, Leyland, M, Leysen, W, Li, Y, Li, L, Liang, Y, Likonen, J, Linke, J, Linsmeier, C, Lipschultz, B, Litaudon, X, Liu, G, Lloyd, B, Lo Schiavo, Vp, Loarer, T, Loarte, A, Lomanowski, B, Lomas, Pj, Lonnroth, J, Lopez, Jm, Lorenzini, R, Losada, U, Loughlin, M, Lowry, C, Luce, T, Lucock, R, Lukin, A, Luna, C, Lungaroni, M, Lungu, Cp, Lungu, M, Lunniss, A, Lunt, T, Lupelli, I, Lutsenko, V, Lyssoivan, A, Macheta, P, Macusova, E, Magesh, B, Maggi, C, Maggiora, R, Mahesan, S, Maier, H, Mailloux, J, Maingi, R, Makwana, R, Malaquias, A, Malinowski, K, Malizia, A, Manas, P, Manduchi, G, Manso, Me, Mantica, P, Mantsinen, M, Manzanares, A, Maquet, P, Marandet, Y, Marcenko, N, Marchetto, C, Marchuk, O, Marconato, N, Mariani, A, Marin, M, Marinelli, M, Marinucci, M, Markovic, T, Marocco, D, Marot, L, Marsh, J, Martin, A, de Aguilera, Am, Martin-Solis, Jr, Martone, R, Martynova, Y, Maruyama, S, Maslov, M, Matejcik, S, Mattei, M, Matthews, Gf, Matveev, D, Matveeva, E, Mauriya, A, Maviglia, F, May-Smith, T, Mayer, M, Mayoral, Ml, Mazon, D, Mazzotta, C, Mcadams, R, Mccarthy, Pj, Mcclements, Kg, Mccormack, O, Mccullen, Pa, Mcdonald, D, Mchardy, M, Mckean, R, Mckehon, J, Mcnamee, L, Meadowcroft, C, Meakins, A, Medley, S, Meigh, S, Meigs, Ag, Meisl, G, Meiter, S, Meitner, S, Meneses, L, Menmuir, S, Mergia, K, Merle, A, Merriman, P, Mertens, P, Meshchaninov, S, Messiaen, A, Meyer, H, Michling, R, Milanesio, D, Militello, F, Militello-Asp, E, Milocco, A, Miloshevsky, G, Mink, F, Minucci, S, Miron, I, Mistry, S, Miyoshi, Y, Mlynar, J, Moiseenko, V, Monaghan, P, Monakhov, I, Moon, S, Mooney, R, Moradi, S, Morales, J, Moran, J, Mordijck, S, Moreira, L, Moro, F, Morris, J, Moser, L, Mosher, S, Moulton, D, Mrowetz, T, Muir, A, Muraglia, M, Murari, A, Muraro, A, Murphy, S, Muscat, P, Muthusonai, N, Myers, C, Asakura, Nn, N'Konga, B, Nabais, F, Naish, R, Naish, J, Nakano, T, Napoli, F, Nardon, E, Naulin, V, Nave, Mff, Nedzelskiy, I, Nemtsev, G, Nesenevich, V, Nespoli, F, Neto, A, Neu, R, Neverov, V, Newman, M, Ng, S, Nicassio, M, Nielsen, Ah, Nina, D, Nishijima, D, Noble, C, Nobs, Cr, Nocente, M, Nodwell, D, Nordlund, K, Nordman, H, Normanton, R, Noterdaeme, Jm, Nowak, S, Nunes, I, O'Gorman, T, O'Mullane, M, Oberkofler, M, Oberparleiter, M, Odupitan, T, Ogawa, Mt, Okabayashi, M, Oliver, H, Olney, R, Omoregie, L, Ongena, J, Orsitto, F, Orszagh, J, Osborne, T, Otin, R, Owen, A, Owen, T, Paccagnella, R, Packer, Lw, Pajuste, E, Pamela, S, Panja, S, Papp, P, Papp, G, Parail, V, Pardanaud, C, Diaz, Fp, Parsloe, A, Parsons, N, Parsons, M, Pasqualotto, R, Passeri, M, Patel, A, Pathak, S, Patten, H, Pau, A, Pautasso, G, Pavlichenko, R, Pavone, A, Pawelec, E, Soldan, Cp, Peackoc, A, Pehkonen, Sp, Peluso, E, Penot, C, Penzo, J, Pepperell, K, Pereira, R, Cippo, Ep, von Thun, Cp, Pericoli, V, Peruzzo, S, Peterka, M, Petersson, P, Petravich, G, Petre, A, Petrzilka, V, Philipps, V, Pigatto, L, Pillon, M, Pinches, S, Pintsuk, G, Piovesan, P, de Sa, Wp, dos Reis, Ap, Piron, L, Piron, C, Pironti, A, Pisano, F, Pitts, R, Plyusnin, V, Poli, Fm, Pomaro, N, Pompilian, Og, Pool, P, Popovichev, S, Poradzinski, M, Porfiri, Mt, Porosnicu, C, Porton, M, Possnert, G, Potzel, S, Poulipoulis, G, Powell, T, Prajapati, V, Prakash, R, Predebon, I, Prestopino, G, Price, D, Price, M, Price, R, Primetzhofer, D, Prior, P, Pucella, G, Puglia, P, Puiatti, Me, Purahoo, K, Pusztai, I, Putterich, T, Rachlew, E, Rack, M, Ragona, R, Rainford, M, Raj, P, Rakha, A, Ramogida, G, Ranjan, S, Rapson, Cj, Rasmussen, D, Rasmussen, Jj, Rathod, K, Ratta, G, Ratynskaia, S, Ravera, G, Rebai, M, Reed, A, Refy, D, Regana, J, Reich, M, Reid, N, Reimold, F, Reinhart, M, Reinke, M, Reiser, D, Rendell, D, Reux, C, Cortes, Sdar, Reynolds, S, Ricci, D, Richiusa, M, Rigamonti, D, Rimini, Fg, Risner, J, Riva, M, Rivero-Rodriguez, J, Roach, C, Robins, R, Robinson, S, Robson, D, Rodionov, R, Rodrigues, P, Rodriguez, J, Rohde, V, Romanelli, M, Romanelli, F, Romanelli, S, Romazanov, J, Rowe, S, Rubel, M, Rubinacci, G, Rubino, G, Ruchko, L, Ruset, C, Rzadkiewicz, J, Saarelma, S, Sabot, R, Saez, X, Safi, E, Sahlberg, A, Saibene, G, Saleem, M, Salewski, M, Salmi, A, Salmon, R, Salzedas, F, Samm, U, Sandiford, D, Santa, P, Santala, Mik, Santos, B, Santucci, A, Sartori, F, Sartori, R, Sauter, O, Scannell, R, Schluck, F, Schlummer, T, Schmid, K, Schmuck, S, Schopf, K, Schweinzer, J, Schworer, D, Scott, Sd, Sergienko, G, Sertoli, M, Shabbir, A, Sharapov, Se, Shaw, A, Sheikh, H, Shepherd, A, Shevelev, A, Shiraki, D, Shumack, A, Sias, G, Sibbald, M, Sieglin, B, Silburn, S, Silva, J, Silva, A, Silva, C, Silvagni, D, Simmons, P, Simpson, J, Sinha, A, Sipila, Sk, Sips, Acc, Siren, P, Sirinelli, A, Sjostrand, H, Skiba, M, Skilton, R, Skvara, V, Slade, B, Smith, R, Smith, P, Smith, Sf, Snoj, L, Soare, S, Solano, Er, Somers, A, Sommariva, C, Sonato, P, Sos, M, Sousa, J, Sozzi, C, Spagnolo, S, Sparapani, P, Spelzini, T, Spineanu, F, Sprada, D, Sridhar, S, Stables, G, Stallard, J, Stamatelatos, I, Stamp, Mf, Stan-Sion, C, Stancar, Z, Staniec, P, Stankunas, G, Stano, M, Stavrou, C, Stefanikova, E, Stepanov, I, Stephen, Av, Stephen, M, Stephens, J, Stevens, B, Stober, J, Stokes, C, Strachan, J, Strand, P, Strauss, Hr, Strom, P, Studholme, W, Subba, F, Suchkov, E, Summers, Hp, Sun, H, Sutton, N, Svensson, J, Sytnykov, D, Szabolics, T, Szepesi, G, Suzuki, Tt, Tabares, F, Tadic, T, Tal, B, Tala, T, Taliercio, C, Tallargio, A, Tanaka, K, Tang, W, Tardocchi, M, Tatali, R, Taylor, D, Tegnered, D, Telesca, G, Teplova, N, Teplukhina, A, Terranova, D, Terry, C, Testa, D, Tholerus, E, Thomas, J, Thompson, Vk, Thornton, A, Tierens, W, Tiseanu, I, Tojo, H, Tokitani, M, Tolias, P, Tomes, M, Trimble, P, Tripsky, M, Tsalas, M, Tsavalas, P, Tskhakaya, D, Jun, Dt, Turner, I, Turner, Mm, Turnyanskiy, M, Tvalashvili, G, Tyshchenko, M, Uccello, A, Uljanovs, J, Urano, H, Urban, A, Urbanczyk, G, Uytdenhouwen, I, Vadgama, A, Valcarcel, D, Vale, R, Valentinuzzi, M, Valerii, K, Valisa, M, Olivares, Pv, Valovic, M, Van Eester, D, Van Renterghem, W, van Rooij, Gj, Varje, J, Vartanian, S, Vasava, K, Vasilopoulou, T, Vecsei, M, Vega, J, Ventre, S, Verdoolaege, G, Verona, C, Rinati, Gv, Veshchev, E, Vianello, N, Vicente, J, Viezzer, E, Villari, S, Villone, F, Vincent, M, Vincenzi, P, Vinyar, I, Viola, B, Vitins, A, Vizvary, Z, Vlad, M, Voitsekhovitch, I, Voltolina, D, von Toussaint, U, Vondracek, P, Vuksic, M, Wakeling, B, Waldon, C, Walkden, N, Walker, R, Walker, M, Walsh, M, Wang, N, Wang, E, Warder, S, Warren, R, Waterhouse, J, Watts, C, Wauters, T, Webb, M, Weckmann, A, Weiland, J, Weiland, M, Weisen, H, Weiszflog, M, Welch, P, West, A, Wheatley, M, Wheeler, S, Whitehead, Am, Whittaker, D, Widdowson, Am, Wiesen, S, Wilkie, G, Williams, J, Willoughby, D, Wilson, J, Wilson, I, Wilson, Hr, Wischmeier, M, Withycombe, A, Witts, D, Wolfrum, E, Wood, R, Woodley, R, Woodley, C, Wray, S, Wright, Jc, Wright, P, Wukitch, S, Wynn, A, Xiang, L, Xu, T, Xue, Y, Yadikin, D, Yakovenko, Y, Yanling, W, Yavorskij, V, Young, I, Young, R, Young, D, Zacks, J, Zagorski, R, Zaitsev, F, Zakharov, L, Zanino, R, Zarins, A, Zarins, R, Fernandez, Dz, Zastrow, Kd, Zerbini, M, Zhang, W, Zhou, Y, Zilli, E, Zocco, A, Zoita, V, Zoletnik, S, Zwingmann, W, Zychor, I, and JET Contributors
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Tokamak ,Plasma turbulence ,Extrapolation ,turbulence ,transport ,plasma, JET ,7. Clean energy ,01 natural sciences ,010305 fluids & plasmas ,law.invention ,law ,Physics::Plasma Physics ,jet ,0103 physical sciences ,010306 general physics ,plasma ,Physics ,Shearing (physics) ,[PHYS]Physics [physics] ,Turbulence ,Plasma ,Mechanics ,JET ,Condensed Matter Physics ,Nuclear Energy and Engineering ,Pinch - Abstract
See also: Plasma Physics and Controlled Fusion, 61, 104002 (2019)Special Issue on the 2018 Joint Varenna-Lausanne International Workshop on the Theory of Fusion Plasmas; International audience; Developing successful tokamak operation scenarios, as well as confident extrapolation of present-day knowledge requires a rigorous understanding of plasma turbulence, which largely determines the quality of the confinement. In particular, accurate particle transport predictions are essential due to the strong dependence of fusion power or bootstrap current on the particle density details. Here, gyrokinetic turbulence simulations are performed with physics inputs taken from a JET power scan, for which a relatively weak degradation of energy confinement and a significant density peaking is obtained with increasing input power. This way physics parameters that lead to such increase in the density peaking shall be elucidated. While well-known candidates, such as the collisionality, previously found in other studies are also recovered in this study, it is furthermore found that edge $E×B$ shearing may adopt a crucial role by enhancing the inward pinch. These results may indicate that a plasma with rotational shear could develop a stronger density peaking as compared to a non-rotating one, because its inward convection is increased compared to the outward diffusive particle flux as long as this rotation has a significant on $E$X$B$ flow shear stabilisation. The possibly significant implications for future devices, which will exhibit much less torque compared to present day experiments, are discussed.
20. Hiring in the Pediatric Hospital Medicine Board Certification Era: PHM Leader Perspectives.
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Osburn TS, McCarthy PJ, Dawlett M, LaRussa L, DeLeon S, and McKnight H
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- Humans, Cross-Sectional Studies, Hospital Medicine education, Pediatrics education, Specialty Boards, United States, Hospitalists education, Leadership, Surveys and Questionnaires, Certification, Personnel Selection standards, Hospitals, Pediatric
- Abstract
Objectives: The designation of pediatric hospital medicine (PHM) as a board-certified (BC) subspecialty has led to uncertainty about the importance of PHM board certification in hiring pediatric hospitalists and ambiguity in counseling trainees interested in PHM careers about the decision to pursue fellowship. We sought to determine the importance of PHM board eligibility or certification in hiring practices., Methods: We conducted an online, cross-sectional, survey-based study of individuals who self-identified as PHM division leadership utilizing the PHM Division Director Listserv and participant recruitment at a national meeting., Results: A total of 86 responses were received. A total of 64% (30/47) of university-setting hospitals, 77% (17/28) of community hospitals, and 100% (11/11) of combined settings reported that they will hire applicants who are not board-eligible (BE) or BC (P = .83). Of the hospitals who will be hiring non-BE hospitalists, 50% of university settings, 77% of community settings, and 55% of combined settings plan to give equal consideration to both BE and non-BE applicants (P = .21). A total of 57% (21/37) of programs with a PHM fellowship felt that fellowship training was an important or very important consideration in hiring, compared with 27% (13/49) of programs without a PHM fellowship (P = .04)., Conclusions: Programs with a PHM fellowship were significantly more likely to believe that fellowship training is an important consideration in hiring hospitalists. PHM board certification and fellowship training are perceived as more important by university-based programs, although all settings will consider hiring applicants who are not BC or BE., (Copyright © 2024 by the American Academy of Pediatrics.)
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- 2024
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21. A 'PEaRL' of Support and Cooperative Learning: A Pilot Study Shifting the Sands of the Dreaded Morbidity and Mortality Conference.
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Yale SC, Porada K, and McCarthy PJ
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- Humans, Pilot Projects, Wisconsin, Female, Pediatrics education, Male, Patient Safety, Morbidity, Curriculum
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Background: When unanticipated and/or poor patient outcomes occur, clinicians frequently experience guilt, anger, psychological distress, and fear, which can be intensified by traditional morbidity and mortality conferences., Methods: The Pediatric Event Review and Learning (PEaRL) curriculum was developed to discuss unanticipated and/or poor patient outcomes and foster support while highlighting foundational safety concepts. Pre- and post-implementation evaluations of quarterly cased-based sessions were completed., Results: All respondents endorsed that unanticipated and/or poor patient outcomes affected their mood, well-being, and functioning. Post-implementation of the PEaRL curriculum, significantly more respondents endorsed existence of a safe environment and structured format to discuss these outcomes, as well as feeling more supported., Discussion: The PEaRL curriculum provides a valuable opportunity for trainees and experienced clinicians alike to explore and discuss unanticipated and/or poor patient outcomes while addressing key patient safety principles., (Copyright© Board of Regents of the University of Wisconsin System and The Medical College of Wisconsin, Inc.)
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- 2024
22. The sporting resilience model: A systematic review of resilience in sport performers.
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Gupta S and McCarthy PJ
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We systematically reviewed resilience research in sport and exercise psychology. Sample included 92 studies comprising empirical qualitative and quantitative studies, mixed-method studies, review studies and conceptual/theoretical studies on psychological resilience in sports context. From the findings, we synthesized an evidence-based sport-specific definition and meta-model of "Sporting Resilience." The review incorporates evidence from global culture contexts and evidence synthesized into the new definition and meta-model to achieve its aim. Conceptual detail and testability of the operational definition is provided. Sporting resilience provides a guiding framework for research and applied practice in a testable, objective manner. The new theoretical meta-model of resilience is derived from systematic evidence from sport psychology with theoretical considerations from positive and clinical psychology allowing generalizability. This original theory posits that there is a resilience filter comprised of biopsychosocial protective factors. The strength of this filter determines the impact of adversity and establishes the trajectory of positive adaptation. The findings of the review are used to discuss potential avenues of future research for psychological resilience in sports psychology., Systematic Review Registration: https://doi.org/10.17605/OSF.IO/AFWRU., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The handling editor declared a past co-authorship with the author PM., (Copyright © 2022 Gupta and McCarthy.)
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- 2022
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23. Brominated and Sulfur-Containing Angucyclines Derived from a Single Pathway: Identification of Nocardiopsistins D-F.
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Xu D, Metz J, Harmody D, Peterson T, Winder P, Guzmán EA, Russo R, McCarthy PJ, Wright AE, and Wang G
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- Vancomycin Resistance, Staphylococcus aureus, Anti-Bacterial Agents pharmacology, Microbial Sensitivity Tests, Sulfur pharmacology, Methicillin-Resistant Staphylococcus aureus
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One novel brominated nocardiopsistin D ( 1 ) and two new sulfur-containing nocardiopsistins E-F ( 2 - 3 ) were identified from Nocardiopsis sp. HB-J378. The biosynthetic gene cluster ncd featuring a brominase was identified. Compounds 1 - 3 exhibited significant anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) activities with minimum inhibitory concentrations (MICs) of 0.098, 3.125, and 0.195 μg/mL, respectively. The single bromination in 1 drastically enhanced the anti-MRSA activity by 128-fold without altering cell toxicity and acquired new activities against the bacterial pathogens vancomycin-resistant S. aureus (VRSA), Enterococcus faecium , and Bacillus cereus .
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- 2022
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24. Optimizing the nutrition support care model: Analysis of survey data.
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Mundi MS, Mechanick JI, Mohamed Elfadil O, Patel JJ, Bonnes SL, Blackmer AB, Christian VJ, Hennessy SA, Hurt RT, Jain A, Kaspar MB, Katz J, Labossiere R, Limketkai BN, McCarthy PJ, Morrison CA, Newberry C, Pimiento JM, Rosenthal MD, Taylor B, and McClave SA
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- Humans, Nutritional Support methods, Patient Care Team, Surveys and Questionnaires, United States, Malnutrition prevention & control, Malnutrition therapy, Nutrition Therapy
- Abstract
Background: Malnutrition is underrecognized and underdiagnosed, despite high prevalence rates and associated poor clinical outcomes. The involvement of clinical nutrition experts, especially physicians, in the care of high-risk patients with malnutrition remains low despite evidence demonstrating lower complication rates with nutrition support team (NST) management. To facilitate solutions, a survey was designed to elucidate the nature of NSTs and physician involvement and identify needs for novel nutrition support care models., Methods: This survey assessed demographics of NSTs, factors contributing to the success of NSTs, elements of nutrition education, and other barriers to professional growth., Results: Of 255 respondents, 235 complete surveys were analyzed. The geographic distribution of respondents correlated with population concentrations of the United States (r = 90.8%, p < .0001). Most responding physicians (46/57; 80.7%) reported being a member of NSTs, compared with 56.5% (88/156) of dietitians. Of those not practicing in NSTs (N = 81/235, 34.4%), 12.3% (10/81) reported an NST was previously present at their institution but had been disbanded. Regarding NSTs, financial concerns were common (115/235; 48.9%), followed by leadership (72/235; 30.6%), and healthcare professional (HCP) interest (55/235; 23.4%). A majority (173/235; 73.6%) of all respondents wanted additional training in nutrition but reported insufficient protected time, ability to travel, or support from administrators or other HCPs., Conclusion: Core actions resulting from this survey focused on formalizing physician roles, increasing interdisciplinary nutrition support expertise, utilizing cost-effective screening for malnutrition, and implementing intervention protocols. Additional actions included increasing funding for clinical practice, education, and research, all within an expanded portfolio of pragmatic nutrition support care models., (© 2022 American Society for Parenteral and Enteral Nutrition.)
- Published
- 2022
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25. Desulfoluna spp. form a cosmopolitan group of anaerobic dehalogenating bacteria widely distributed in marine sponges.
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Horna-Gray I, Lopez NA, Ahn Y, Saks B, Girer N, Hentschel U, McCarthy PJ, Kerkhof LJ, and Häggblom MM
- Subjects
- Anaerobiosis, Animals, Bacteria genetics, Mediterranean Sea, Phylogeny, Microbiota, Porifera microbiology
- Abstract
Host-specific microbial communities thrive within sponge tissues and this association between sponge and associated microbiota may be driven by the organohalogen chemistry of the sponge animal. Several sponge species produce diverse organobromine secondary metabolites (e.g. brominated phenolics, indoles, and pyrroles) that may function as a chemical defense against microbial fouling, infection or predation. In this study, anaerobic cultures prepared from marine sponges were amended with 2,6-dibromophenol as the electron acceptor and short chain organic acids as electron donors. We observed reductive dehalogenation from diverse sponge species collected at disparate temperate and tropical waters suggesting that biogenic organohalides appear to enrich for populations of dehalogenating microorganisms in the sponge animal. Further enrichment by successive transfers with 2,6-dibromophenol as the sole electron acceptor demonstrated the presence of dehalogenating bacteria in over 20 sponge species collected from temperate and tropical ecoregions in the Atlantic and Pacific Oceans and the Mediterranean Sea. The enriched dehalogenating strains were closely related to Desulfoluna spongiiphila and Desulfoluna butyratoxydans, suggesting a cosmopolitan association between Desulfoluna spp. and various marine sponges. In vivo reductive dehalogenation in intact sponges was also demonstrated. Organobromide-rich sponges may thus provide a specialized habitat for organohalide-respiring microbes and D. spongiiphila and/or its close relatives are responsible for reductive dehalogenation in geographically widely distributed sponge species., (© The Author(s) 2022. Published by Oxford University Press on behalf of FEMS.)
- Published
- 2022
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26. 3-D Culture of Marine Sponge Cells for Production of Bioactive Compounds.
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Urban-Gedamke E, Conkling M, McCarthy PJ, Wills PS, and Pomponi SA
- Subjects
- Animals, Aquatic Organisms, Biotechnology, Aquaculture, Biological Products metabolism, Porifera
- Abstract
Production of sponge-derived bioactive compounds in vitro has been proposed as an alternative to wild harvest, aquaculture, and chemical synthesis to meet the demands of clinical drug development and manufacture. Until recently, this was not possible because there were no marine invertebrate cell lines. Recent breakthroughs in the development of sponge cell lines and rapid cell division in improved nutrient media now make this approach a viable option. We hypothesized that three-dimensional (3-D) cell cultures would better represent how sponges function in nature, including the production of bioactive compounds. We successfully cultured sponge cells in 3-D matrices using FibraCel
® disks, thin hydrogel layers, and gel microdroplets (GMDs). For in vitro production of bioactive compounds, the use of GMDs is recommended. Nutrients and sponge products rapidly diffuse into and out of the 3-D matrix, the GMDs may be scaled up in spinner flasks, and cells and/or secreted products can be easily recovered. Research on scale-up and production is in progress in our laboratory.- Published
- 2021
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27. Sporting Resilience During COVID-19: What Is the Nature of This Adversity and How Are Competitive Elite Athletes Adapting?
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Gupta S and McCarthy PJ
- Abstract
The COVID-19 pandemic is a global health issue which has severely disrupted and deferred several landmark international sporting competitions. Like the general population, athletes have faced direct psychological consequences from COVID-19 in addition to cancelation of events, loss of support, lack of training, loss of earnings, hypervigilance, and anxiety among others. The aim of the present research was to identify the adversity experiences of athletes caused by COVID-19 (study 1) and explore the process of resilience used by competitive elite athletes for positive adaptation (study 2). Research has indicated psychological resilience to be a protective factor against similar adversities in the sporting context. The study uses an across-cases qualitative design comparing the real-time lived experiences of athletes during COVID-19 using narrative analysis. Data were collected from 10 competitive elite athletes from various countries, as part of a larger doctoral dissertation study during the lockdown period, using in-depth experiential interviews. Study 1 presents detailed narratives on the loss and incongruence, which were the two major adversities experienced. Study 2 outlines the process of resilience as narrated by the participants through the emergent and minimal-impact resilience trajectories. We discuss recommendations for interventions and the role of sports psychologists, coaches, and sporting organizations in ensuring athletes' mental health and their rehabilitation into post-COVID sports life., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2021 Gupta and McCarthy.)
- Published
- 2021
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28. Genome Sequence of Streptomyces sp. Strain HB-N217, Isolated from the Marine Sponge Forcepia sp.
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Xavier RKM, Xu D, McCarthy PJ, Yang S, and Wang G
- Abstract
The genome sequence of the Forcepia sponge-derived bacterium Streptomyces sp. strain HB-N217 was determined, with approximately 8.25 Mbp and a G+C content of 72.1%. Thirty biosynthetic gene clusters that bear the capability to produce secondary metabolites were predicted. The results will aid marine natural product chemistry and sponge-microbe association studies., (Copyright © 2021 Xavier et al.)
- Published
- 2021
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29. Defining the sediment prokaryotic communities of the Indian River Lagoon, FL, USA, an Estuary of National Significance.
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Bradshaw DJ 2nd, Dickens NJ, Trefry JH, and McCarthy PJ
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- Archaea isolation & purification, Bacteria isolation & purification, Estuaries, Florida, Geologic Sediments analysis, Archaea classification, Bacteria classification, Biodiversity, Geologic Sediments microbiology, Prokaryotic Cells classification, Rivers microbiology, Water Pollutants, Chemical analysis
- Abstract
The Indian River Lagoon, located on the east coast of Florida, USA, is an Estuary of National Significance and an important economic and ecological resource. The Indian River Lagoon faces several environmental pressures, including freshwater discharges through the St. Lucie Estuary; accumulation of anoxic, fine-grained, organic-rich sediment; and metal contamination from agriculture and marinas. Although the Indian River Lagoon has been well-studied, little is known about its microbial communities; thus, a two-year 16S amplicon sequencing study was conducted to assess the spatiotemporal changes of the sediment bacterial and archaeal groups. In general, the Indian River Lagoon exhibited a prokaryotic community that was consistent with other estuarine studies. Statistically different communities were found between the Indian River Lagoon and St. Lucie Estuary due to changes in porewater salinity causing microbes that require salts for growth to be higher in the Indian River Lagoon. The St. Lucie Estuary exhibited more obvious prokaryotic seasonality, such as a higher relative abundance of Betaproteobacteriales in wet season and a higher relative abundance of Flavobacteriales in dry season samples. Distance-based linear models revealed these communities were more affected by changes in total organic matter and copper than changes in temperature. Anaerobic prokaryotes, such as Campylobacterales, were more associated with high total organic matter and copper samples while aerobic prokaryotes, such as Nitrosopumilales, were more associated with low total organic matter and copper samples. This initial study fills the knowledge gap on the Indian River Lagoon bacterial and archaeal communities and serves as important data for future studies to compare to determine possible future changes due to human impacts or environmental changes., Competing Interests: The authors have declared that no competing interests exist. In specific relation to the commercial funder MyFloridaSpecialtyPlate, none of the authors have any of the following financial competing interests to declare: ownership of stocks or shares, paid employment or consultancy, board membership, patent applications, or marketed products. None of the funders involved in this research have any policies nor do any of the authors have an involvement with these funders which would alter our adherence to PLOS ONE policies on sharing data and materials.
- Published
- 2020
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30. The first juvenile dromaeosaurid (Dinosauria: Theropoda) from Arctic Alaska.
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Chiarenza AA, Fiorillo AR, Tykoski RS, McCarthy PJ, Flaig PP, and Contreras DL
- Subjects
- Alaska, Animals, Arctic Regions, Biological Evolution, Dinosaurs genetics, Phylogeny, Dinosaurs anatomy & histology, Fossils anatomy & histology, Tooth anatomy & histology
- Abstract
Compared to the osteological record of herbivorous dinosaurs from the Late Cretaceous Prince Creek Formation of northern Alaska, there are relatively fewer remains of theropods. The theropod record from this unit is mostly comprised of isolated teeth, and the only non-dental remains known can be attributed to the troodontid cf. Troodon and the tyrannosaurid Nanuqsaurus. Thus far, the presence of members of Dromaeosauridae has been limited to isolated teeth. Here we describe a symphyseal portion of a small dentary with two ziphodont teeth. Based on tooth shape, denticle morphology, and the position of the Meckelian groove, we attribute this partial dentary to a saurornitholestine dromaeosaurid. The fibrous bone surface, small size, and higher number of mesial denticles compared to distal ones point to a juvenile growth stage for this individual. Multivariate comparison of theropod teeth morphospace by means of principal component analysis reveals an overlap between this dentary and Saurornitholestinae dromaeosaurid morphospace, a result supported by phylogenetic analyses. This is the first confirmed non-dental fossil specimen from a member of Dromaeosauridae in the Arctic, expanding on the role of Beringia as a dispersal route for this clade between Asia and North America. Furthermore, the juvenile nature of this individual adds to a growing body of data that suggests Cretaceous Arctic dinosaurs of Alaska did not undergo long-distance migration, but rather they were year-round residents of these paleopolar latitudes., Competing Interests: The authors have declared that no competing interests exist.
- Published
- 2020
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31. First Records of 'Flagship' Soil Ciliates in North America.
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Hines HN, McCarthy PJ, and Esteban GF
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- Cysts, Florida, North America, Phylogeography, RNA, Ribosomal, 18S genetics, Ciliophora classification, Ciliophora isolation & purification, Phylogeny, Soil Microbiology
- Abstract
'Flagship' ciliates were investigated from soil samples collected in Florida, USA. This was undertaken to determine if species thought to be restricted to a given world region could be uncovered from similar habitats in a novel location, e.g. another continent. Two species of Condylostomides were discovered, and recorded from the North American continent for the first time. Condylostomides etoschensis was known only from Africa, but was found to be thriving in a Florida study site. An 18S rDNA sequence for this species was determined for the first time. Also discovered from the same study site was the ciliate Condylostomides coeruleus, previously known only from Central and South America. These two 'flagship' ciliates were found in the same habitat, from a continent well outside of their previously recorded biogeographies. Molecular sequencing and microscopy investigations were conducted to form the baseline for future work within this genus. Soil ciliates can obtain large population numbers and form cysts and are therefore likely able to disperse globally. These new records provide additional evidence that large distances, even between continents, do not hinder microbes from thriving globally. The absence of these conspicuously-colored gold and blue ciliates from previous studies is likely due to undersampling, rather than to any physical barriers., (Copyright © 2020 Elsevier GmbH. All rights reserved.)
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- 2020
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32. Data supporting Maastrichtian paleoclimate variables applying a multi proxy approach to a paleosol profile, Arctic Alaska.
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Salazar-Jaramillo S, McCarthy PJ, Ochoa A, Fowell SJ, and Longstaffe FJ
- Abstract
We provide the dataset of climate variables related to the research article "Paleoclimate reconstruction of the Prince Creek Formation, Arctic Alaska, during Maastrichtian global warming" [1]. The dataset includes mean annual precipitation (MAP) values determined using two independent proxies, estimates of the oxygen isotope composition of meteoric water (δ
18 Ow ) obtained from smectites and a comparison with previously published siderite data. We also provide the data used to calculate the total flux of CO2 required for the weathering of silicates. This dataset is an example of a multi proxy approach that could add further insight for researchers in the selection of suitable proxies for paleoclimatic interpretations., (© 2020 The Author(s).)- Published
- 2020
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33. Dinosaur ichnology and sedimentology of the Chignik Formation (Upper Cretaceous), Aniakchak National Monument, southwestern Alaska; Further insights on habitat preferences of high-latitude hadrosaurs.
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Fiorillo AR, Kobayashi Y, McCarthy PJ, Tanaka T, Tykoski RS, Lee YN, Takasaki R, and Yoshida J
- Subjects
- Animals, Ecosystem, Environment, Geography, Parks, Recreational, Dinosaurs anatomy & histology, Fossils, Paleontology
- Abstract
While there are now numerous records of dinosaurs from Cretaceous rocks around the state of Alaska, very few fossil records of terrestrial vertebrates are known from the Mesozoic rocks of the southwestern part of the state. Here we report the new discovery of extensive occurrences of dinosaur tracks from Aniakchak National Monument of the Alaska Peninsula. These tracks are in the Late Cretaceous (Maastrichtian) Chignik Formation, a cyclic sequence of rocks, approximately 500-600 m thick, representing shallow marine to nearshore marine environments in the lower part and continental alluvial coastal plain environments in the upper part of the section. These rocks are part of the Peninsular Terrane and paleomagnetic reconstructions based on the volcanic rocks of this terrane suggest that the Chignik Formation was deposited at approximately its current latitude which is almost 57° N. Recent field work in Aniakchak National Monument has revealed over 75 new track sites, dramatically increasing the dinosaur record from the Alaska Peninsula. Most of the combined record of tracks can be attributed to hadrosaurs, the plant-eating duck-billed dinosaurs. Tracks range in size from those made by full-grown adults to juveniles. Other tracks can be attributed to armored dinosaurs, meat-eating dinosaurs, and two kinds of fossil birds. The track size of the predatory dinosaur suggests a body approximately 6-7 m long, about the estimated size of the North Slope tyrannosaurid Nanuqsaurus. The larger bird tracks resemble Magnoavipes denaliensis previously described from Denali National Park, while the smaller bird tracks were made by a bird about the size of a modern Willet. Previous interdisciplinary sedimentologic and paleontologic work in the correlative and well-known dinosaur bonebeds of the Prince Creek Formation 1400km-1500km further north in Alaska suggested that high-latitude hadrosaurs preferred distal coastal plain or lower delta plain habitats. The ichnological record being uncovered in the Chignik Formation of southwestern Alaska is showing that the hadrosaur tracks here were also made in distal coastal and delta plain conditions. This similarity may corroborate the habitat preference model for Cretaceous high-latitude dinosaurs proposed for the data gathered from the Prince Creek Formation, and may indicate that at least Beringian hadrosaurids had similar habitat preferences regardless of latitude., Competing Interests: The authors have declared that no competing interests exist.
- Published
- 2019
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34. Perfusion Methods and Modifications to the Cardiopulmonary Bypass Circuit for Midline Unifocalization Procedures.
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Margetson TD, Sleasman J, Kollmann S, McCarthy PJ, Jahadi O, Sheff D, Shuttleworth P, Mainwaring RD, and Hanley FL
- Subjects
- Cardiopulmonary Bypass, Collateral Circulation, Humans, Infant, Pulmonary Artery, Cardiac Surgical Procedures, Pulmonary Atresia
- Abstract
Pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries (PA/VSD/MAPCAs) is a rare form of congenital heart disease. The midline unifocalization procedure has been developed for the treatment of PA/VSD/MAPCAs. These are complex and very lengthy procedures that require an entirely different method of perfusion. The purpose of this study was to review our perfusion modifications to support these unifocalization procedures. Sixty-four unifocalization procedures have been performed at our institution during the past 3 years. The median age was 4.1 months (range 1 month-3.5 years) and the median weight at surgery was 4.5 kg (range 3.5-19 kg). The median duration of cardiopulmonary bypass was 352 minutes (range 128-629 minutes), and the median duration of cross-clamp was 24 minutes (range 14-72 minutes). The conduct of surgery included cooling to a rectal perfusion temperature of 25° and a flow rate of 100 mL/kg/min. A pH-stat strategy and del Nido cardioplegia were used. Modifications to the cardiopulmonary bypass circuit include upsizing the oxygenator, reservoir, cannulae, vent catheter, and tubing. All circuits were modified to include the capability of performing an intraoperative flow study. This study is used to determine whether the VSD can be closed during surgery. A collateral flow study circuit is also set up for first-time operations to measure the residual collateral flow after all of the MAPCAs have been harvested. Patients who require midline unifocalization will invariably require very lengthy periods of support on cardiopulmonary bypass. We have adapted our perfusion circuitry to prepare for the demands on the bypass circuit to meet the requirements of this patient population. Our institution has developed a systematic approach for the conduct of perfusion to best serve our patients presenting with PA/VSD/MAPCAs.
- Published
- 2019
35. Marine Microbiome as a Source of Antimalarials.
- Author
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McCarthy PJ, Roberts BF, Carbonell A, Roberts J, Wright AE, and Chakrabarti D
- Abstract
It is important to discover novel antimalarial pharmacophores because of the widespread emergence of Plasmodium falciparum isolates resistant to the available drugs. Secondary metabolites derived from microbes associated with marine invertebrates are a valuable resource for the discovery of novel drug leads. However, the potential of marine microbes as a source of antimalarials has not been explored. We investigated the promise of marine microorganisms for the production of antimalarial activities by testing 2365 diverse microbial extracts using phenotypic screening of a multidrug resistant chloroquine resistant P. falciparum strain. We conducted counter screening against mammalian cells for the 317 active extracts that exhibited more than 70% inhibition at 1 µg/mL. The screen identified 17 potent bioactive leads from a broad range of taxa. Our results establish that the marine microbiome is a rich source of antiplasmodial compounds that warrants in depth exploration.
- Published
- 2019
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36. The First Definite Lambeosaurine Bone From the Liscomb Bonebed of the Upper Cretaceous Prince Creek Formation, Alaska, United States.
- Author
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Takasaki R, Fiorillo AR, Kobayashi Y, Tykoski RS, and McCarthy PJ
- Abstract
The Prince Creek Formation of Alaska, a rock unit that represents lower coastal plain and delta deposits, is one of the most important formations in the world for understanding vertebrate ecology in the Arctic during the Cretaceous. Here we report on an isolated cranial material, supraoccipital, of a lambeosaurine hadrosaurid from the Liscomb Bonebed of the Prince Creek Formation. The lambeosaurine supraoccipital has well-developed squamosal bosses and a short sutural surface with the exoccipital-opisthotic complex, and is similar to lambeosaurine supraoccipitals from the Dinosaur Park Formation in having anteriorly positioned squamosal bosses. Affinities with Canadian lambeosaurines elucidate more extensive faunal exchange between the Arctic and lower paleolatitudes which was previously suggested by the presence of Edmontosaurus, Pachyrhinosaurus, tyrannosaurids, and troodontids in both regions. The presence of one lambeosaurine and nine hadrosaurine supraoccipitals in the Liscomb Bonebed suggests hadrosaurine dominated faunal structure as in the Careless Creek Quarry of the USA that was also deposited under a near-shore environment. It differs from the lambeosaurine dominant structures of localities in Russia and China interpreted as inland environments. This may suggest that lambeosaurines had less preference for near-shore environments than hadrosaurines in both Arctic and lower paleolatitudes.
- Published
- 2019
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37. A case series involving young children presenting with accidental ingestion of amphetamine based stimulants.
- Author
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Wood KE, McCarthy PJ, and Krasowski MD
- Abstract
•Attention Deficity Hyperactivity Disorder (ADHD) affects adults and children.•Stimulant prescribing for ADHD is increasing.•Overdose of amphetamine based stimulants results in a sympathomimetic toxidrome.•Lisdexamfetamine dimesylate is the first prodrug stimulant developed to treat ADHD.
- Published
- 2018
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38. Nocardiopsistins A-C: New angucyclines with anti-MRSA activity isolated from a marine sponge-derived Nocardiopsis sp. HB-J378.
- Author
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Xu D, Nepal KK, Chen J, Harmody D, Zhu H, McCarthy PJ, Wright AE, and Wang G
- Abstract
Marine natural products have become an increasingly important source of new drug leads during recent years. In an attempt to identify novel anti-microbial natural products by bioprospecting deep-sea Actinobacteria, three new angucyclines, nocardiopsistins A-C, were isolated from Nocardiopsis sp. strain HB-J378. Notably, the supplementation of the rare earth salt Lanthanum chloride (LaCl
3 ) during fermentation of HB-J378 significantly increased the yield of these angucyclines. The structures of nocardiopsistins A-C were identified by 1D and 2D NMR and HR-MS data. Nocardiopsistins A-C have activity against MRSA (methicillin-resistant Staphylococcus aureus ) with MICs of 3.12-12.5 μg/mL; the potency of nocardiopsistin B is similar to that of the positive control, chloramphenicol. Bioinformatic analysis of the draft genome of HB-J378 identified a set of three core genes in a biosynthetic gene cluster that encode a typical aromatic or type II polyketide synthase (PKS) system, including ketoacyl:ACP synthase α-subunit (KSα ), β-subunit (KSβ ) and acyl carrier protein (ACP). The production of nocardiopsistins A-C was abolished when the three genes were knocked out, indicating their indispensable role in the production of nocardiopsistins.- Published
- 2018
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39. Note: Internal diamagnetic flux measurements on ASDEX Upgrade.
- Author
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Giannone L, Fischer R, Fuchs JC, Geiger B, Maraschek M, Rittich D, Sieglin B, Bock A, Hobirk J, Kallenbach A, Mertens V, Schuhbeck KH, and McCarthy PJ
- Abstract
Internal diamagnetic flux measurements, with measurement loops and compensation magnetic probes inside the vacuum vessel, are now available on the ASDEX Upgrade tokamak. The measured diamagnetic flux is compared to that predicted by simulations and calculated from equilibrium reconstruction. The diamagnetic flux measured at 2 positions separated toroidally by 180° in the vacuum vessel is compared.
- Published
- 2018
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40. An unusual association of hadrosaur and therizinosaur tracks within Late Cretaceous rocks of Denali National Park, Alaska.
- Author
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Fiorillo AR, McCarthy PJ, Kobayashi Y, Tomsich CS, Tykoski RS, Lee YN, Tanaka T, and Noto CR
- Abstract
We report details of a unique association of hadrosaur and therizinosaur tracks found in the Late Cretaceous lower Cantwell Formation, Denali National Park, central Alaska Range, Alaska. This rock unit is now well-documented as a source of thousands of fossil footprints of vertebrates such as fishes, pterosaurs, and avialan and non-avialan dinosaurs. The lower Cantwell Formation in this area consists of numerous fining-upward successions of conglomerates and pebbly sandstones, cross-stratified and massive sandstones, interbedded sandstones and siltstones, organic-rich siltstones and shales, and rare, thin, bentonites, typically bounded by thin coal seams, and it contains a diverse fossil flora. We report the first North American co-occurrence of tracks attributable to hadrosaurs and therizinosaurs in the lower Cantwell Formation. Although previously un-reported in North America, this association of hadrosaur and therizinosaur tracks is more characteristic of the correlative Nemegt Formation in central Asia, perhaps suggesting that parameters defining the continental ecosystem of central Asia were also present in this part of Alaska during the Latest Cretaceous.
- Published
- 2018
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41. Bioprospecting Deep-Sea Actinobacteria for Novel Anti-infective Natural Products.
- Author
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Xu D, Han L, Li C, Cao Q, Zhu D, Barrett NH, Harmody D, Chen J, Zhu H, McCarthy PJ, Sun X, and Wang G
- Abstract
The global prevalence of drug resistance has created an urgent need for the discovery of novel anti-infective drugs. The major source of antibiotics in current clinical practice is terrestrial actinobacteria; the less-exploited deep-sea actinobacteria may serve as an unprecedented source of novel natural products. In this study, we evaluated 50 actinobacteria strains derived from diverse deep water sponges and environmental niches for their anti-microbial activities against a panel of pathogens including Candida albicans , Clostridium difficile , Staphylococcus aureus , and methicillin-resistant S. aureus (MRSA), and Pseudomonas aeruginosa . More than half of the tested strains (27) were identified as active in at least one assay. The rare earth salt lanthanum chloride (LaCl
3 ) was shown to be as an effective elicitor. Among the 27 strains, the anti-microbial activity of 15 were induced or enhanced by the addition of LaCl3 . This part of study focused on one strain R818, in which potent antifungal activity was induced by the addition of LaCl3 . We found that the LaCl3 -activated metabolites in R818 are likely antimycin-type compounds. One of them, compound 1 , has been purified. Spectroscopic analyses including HR-MS and 1D NMR indicated that this compound is urauchimycin D. The antifungal activity of compound 1 was confirmed with a minimal inhibitory concentration (MIC) of 25 μg/mL; the purified compound also showed a moderate activity against C. difficile . Additional notable strains are: strain N217 which showed both antifungal and antibacterial (including P. aeruginosa ) activities and strain M864 which showed potent activity against C. difficile with an MIC value (0.125 μg/mL) lower than those of vancomycin and metronidazole. Our preliminary studies show that deep-sea actinobacteria is a promising source of anti-infective natural products.- Published
- 2018
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42. Lacosamide Pharmacokinetics in a Critically Ill Patient Receiving Continuous Venovenous Hemofiltration.
- Author
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Franquiz MJ, Kalaria SN, Armahizer MJ, Gopalakrishnan M, McCarthy PJ, and Badjatia N
- Subjects
- Anticonvulsants pharmacokinetics, Anticonvulsants therapeutic use, Humans, Lacosamide pharmacokinetics, Lacosamide therapeutic use, Male, Middle Aged, Status Epilepticus blood, Status Epilepticus drug therapy, Anticonvulsants blood, Critical Illness therapy, Hemofiltration trends, Lacosamide blood
- Abstract
Lacosamide is a new-generation antiepileptic drug (AED) that is eliminated by both hepatic and renal mechanisms. Lacosamide elimination by continuous renal replacement therapy (CRRT) has never been studied. The objective of this case report was to describe lacosamide pharmacokinetics in the setting of CRRT. We describe a single patient admitted to the study center with status epilepticus and multiorgan failure. The patient required both continuous venovenous hemofiltration (CVVH) and several AEDs. He was receiving intravenous lacosamide 200 mg twice/day at steady state prior to sampling. Plasma lacosamide concentrations were derived using a validated high-performance liquid chromatography method. Parameters were calculated using Phoenix WinNonlin 7.1 software. The peak concentration at steady state was 7.7 mg/L, the trough concentration was 5.9 mg/L (goal 5-12 mg/L). The volume of distribution was 0.7 L/kg, the elimination half-life was 21 hours, and the sieving coefficient was 0.8 (± 0.06). Lacosamide was cleared by CVVH as demonstrated by the sieving coefficient, but plasma concentrations remained within goal range throughout the dosing interval. These results may suggest that lacosamide 200 mg twice/day is a useful dosing strategy for critically ill patients who require CVVH., (© 2017 Pharmacotherapy Publications, Inc.)
- Published
- 2018
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43. Editorial: Mental Health Challenges in Elite Sport: Balancing Risk with Reward.
- Author
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MacIntyre TE, Jones M, Brewer BW, Van Raalte J, O'Shea D, and McCarthy PJ
- Published
- 2017
- Full Text
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44. Draft Genome Sequence of Deep-Sea Alteromonas sp. Strain V450 Isolated from the Marine Sponge Leiodermatium sp.
- Author
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Wang G, Barrett NH, and McCarthy PJ
- Abstract
The proteobacterium Alteromonas sp. strain V450 was isolated from the Atlantic deep-sea sponge Leiodermatium sp. Here, we report the draft genome sequence of this strain, with a genome size of approx. 4.39 Mb and a G+C content of 44.01%. The results will aid deep-sea microbial ecology, evolution, and sponge-microbe association studies., (Copyright © 2017 Wang et al.)
- Published
- 2017
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45. Dragmacidin G, a Bioactive Bis-Indole Alkaloid from a Deep-Water Sponge of the Genus Spongosorites.
- Author
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Wright AE, Killday KB, Chakrabarti D, Guzmán EA, Harmody D, McCarthy PJ, Pitts T, Pomponi SA, Reed JK, Roberts BF, Rodrigues Felix C, and Rohde KH
- Subjects
- Animals, Cell Line, Tumor, Humans, Indole Alkaloids pharmacology, Methicillin-Resistant Staphylococcus aureus drug effects, Mycobacterium tuberculosis drug effects, Plasmodium falciparum drug effects, Pyrazines chemistry, Pyrazines pharmacology, Seawater, Indole Alkaloids chemistry, Porifera chemistry
- Abstract
A deep-water sponge of the genus Spongosorites has yielded a bis-indole alkaloid which we have named dragmacidin G. Dragmacidin G was first reported by us in the patent literature and has recently been reported by Hitora et al. from a sponge of the genus Lipastrotheya . Dragmacidin G is the first in this series of compounds to have a pyrazine ring linking the two indole rings. It also has a rare N -(2-mercaptoethyl)-guanidine side chain. Dragmacidin G shows a broad spectrum of biological activity including inhibition of methicillin-resistant Staphylococcus aureus , Mycobacterium tuberculosis , Plasmodium falciparum, and a panel of pancreatic cancer cell lines., Competing Interests: The authors declare no conflict of interest.
- Published
- 2017
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46. Herpes Simplex Proctitis Mimicking Inflammatory Bowel Disease in a Teenaged Male.
- Author
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Sandgren KE, Price NB, Bishop WP, and McCarthy PJ
- Abstract
We report the case of a 17-year-old male who was initially assessed for pain with defecation, bloody rectal discharge, and diarrhea, consistent with proctitis. Though proctitis is most commonly due to inflammatory bowel disease (IBD), infectious etiologies must also be considered, including sexually transmitted causes of infectious proctitis. In discussion of his sexual history, he identified as homosexual and acknowledged engaging in receptive anal intercourse. Rectal biopsies obtained via colonoscopy were culture-positive for herpes simplex virus (HSV), leading to a diagnosis of HSV proctitis and treatment with an appropriate antiviral medication. HSV proctitis is more common in individuals with high-risk sexual practices, including men who have sex with men. While this may be an uncommon diagnosis for pediatricians to make in practice, a high clinical index of suspicion for sexually transmitted infectious proctitis in those with risk factors must be maintained in order to facilitate appropriate testing, treatment, and counseling of affected individuals.
- Published
- 2017
- Full Text
- View/download PDF
47. Cutaneous Granulomas in Dolphins Caused by Novel Uncultivated Paracoccidioides brasiliensis.
- Author
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Vilela R, Bossart GD, St Leger JA, Dalton LM, Reif JS, Schaefer AM, McCarthy PJ, Fair PA, and Mendoza L
- Subjects
- Animal Diseases pathology, Animals, Base Sequence, Biopsy, DNA, Fungal, Phylogeny, Animal Diseases microbiology, Dermatomycoses veterinary, Dolphins, Granuloma veterinary, Paracoccidioides classification, Paracoccidioides genetics, Paracoccidioides isolation & purification, Paracoccidioidomycosis veterinary
- Abstract
Cutaneous granulomas in dolphins were believed to be caused by Lacazia loboi, which also causes a similar disease in humans. This hypothesis was recently challenged by reports that fungal DNA sequences from dolphins grouped this pathogen with Paracoccidioides brasiliensis. We conducted phylogenetic analysis of fungi from 6 bottlenose dolphins (Tursiops truncatus) with cutaneous granulomas and chains of yeast cells in infected tissues. Kex gene sequences of P. brasiliensis from dolphins showed 100% homology with sequences from cultivated P. brasiliensis, 73% with those of L. loboi, and 93% with those of P. lutzii. Parsimony analysis placed DNA sequences from dolphins within a cluster with human P. brasiliensis strains. This cluster was the sister taxon to P. lutzii and L. loboi. Our molecular data support previous findings and suggest that a novel uncultivated strain of P. brasiliensis restricted to cutaneous lesions in dolphins is probably the cause of lacaziosis/lobomycosis, herein referred to as paracoccidioidomycosis ceti.
- Published
- 2016
- Full Text
- View/download PDF
48. Toward the identification, characterization and experimental culture of Lacazia loboi from Atlantic bottlenose dolphin (Tursiops truncatus).
- Author
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Schaefer AM, Reif JS, Guzmán EA, Bossart GD, Ottuso P, Snyder J, Medalie N, Rosato R, Han S, Fair PA, and McCarthy PJ
- Subjects
- Animals, Atlantic Ocean, Granuloma pathology, Histocytochemistry, Lobomycosis microbiology, Lobomycosis pathology, Microscopy, Bottle-Nosed Dolphin microbiology, Lacazia growth & development, Lacazia isolation & purification, Lobomycosis veterinary, Microbiological Techniques methods
- Abstract
Lobomycosis (lacaziosis) is a chronic, granulomatous, fungal infection of the skin and subcutaneous tissues of humans and dolphins. To date, the causative agent, the yeast-like organism Lacazia loboi, has not been grown in the laboratory, and there have been no recent reports describing attempts to culture the organism. As a result, studies on the efficacy of therapeutics and potential environmental reservoirs have not been conducted. Therefore, the objective of the current study was to utilize both classical and novel microbiological methods in order to stimulate growth of Lacazia cells collected from dolphin lesions. This included the experimental inoculation of novel media, cell culture, and the use of artificial skin matrices. Although unsuccessful, the methods and results of this study provide important insight into new approaches that could be utilized in future investigations of this elusive organism., (© The Author 2016. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2016
- Full Text
- View/download PDF
49. Real-time diamagnetic flux measurements on ASDEX Upgrade.
- Author
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Giannone L, Geiger B, Bilato R, Maraschek M, Odstrčil T, Fischer R, Fuchs JC, McCarthy PJ, Mertens V, and Schuhbeck KH
- Abstract
Real-time diamagnetic flux measurements are now available on ASDEX Upgrade. In contrast to the majority of diamagnetic flux measurements on other tokamaks, no analog summation of signals is necessary for measuring the change in toroidal flux or for removing contributions arising from unwanted coupling to the plasma and poloidal field coil currents. To achieve the highest possible sensitivity, the diamagnetic measurement and compensation coil integrators are triggered shortly before plasma initiation when the toroidal field coil current is close to its maximum. In this way, the integration time can be chosen to measure only the small changes in flux due to the presence of plasma. Two identical plasma discharges with positive and negative magnetic field have shown that the alignment error with respect to the plasma current is negligible. The measured diamagnetic flux is compared to that predicted by TRANSP simulations. The poloidal beta inferred from the diamagnetic flux measurement is compared to the values calculated from magnetic equilibrium reconstruction codes. The diamagnetic flux measurement and TRANSP simulation can be used together to estimate the coupled power in discharges with dominant ion cyclotron resonance heating.
- Published
- 2016
- Full Text
- View/download PDF
50. Impact of Growth Restriction and Other Prenatal Risk Factors on Cord Blood Iron Status in Prematurity.
- Author
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McCarthy PJ, Zundel HR, Johnson KR, Blohowiak SE, and Kling PJ
- Subjects
- Female, Humans, Infant, Newborn, Pregnancy, Pregnancy Complications blood, Prospective Studies, Risk Factors, Fetal Blood chemistry, Fetal Growth Retardation blood, Infant, Premature blood, Iron blood
- Abstract
Objective: To determine whether prenatal risk factors (RFs) that predict cord blood iron status in term newborns also predict iron status of premature newborns., Study Design: Cord blood iron indices from 80 preterm newborns were compared with historical and demographic RFs for developing iron deficiency if born at term., Result: The presence of multiple RFs did not incrementally interfere with cord iron status in preterm newborns. Poorer iron status accompanied being small for gestational age in prematurity, but other RFs, including diabetes, had relatively little impact., Conclusion: Growth-restricted preterm newborns are at risk for poor iron endowment, likely due to uteroplacental insufficiency. Other RFs were less impactful on iron status of premature newborns than in term newborns, likely reflecting that disruptive effects of RFs are more impactful in the third trimester. Understanding RFs for poor iron endowment is important for clinical recognition and treatment of premature babies.
- Published
- 2016
- Full Text
- View/download PDF
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