Search

Your search keyword '"Mazzi B"' showing total 257 results
Start Over Author "Mazzi B"
257 results on '"Mazzi B"'

3. Exocrine pancreas function is impaired in adult relatives of patients with type 1 diabetes

Author

Giovenzana, A, Vecchio, F, Cugnata, F, Nonis, A, Mandelli, A, Stabilini, A, Mazzi, B, De Pellegrin, M, Laurenzi, A, Bonfanti, R, Battaglia, M, Bosi, E, Petrelli, A, Giovenzana A., Vecchio F., Cugnata F., Nonis A., Mandelli A., Stabilini A., Mazzi B. A., De Pellegrin M., Laurenzi A., Bonfanti R., Battaglia M., Bosi E., Petrelli A., Giovenzana, A, Vecchio, F, Cugnata, F, Nonis, A, Mandelli, A, Stabilini, A, Mazzi, B, De Pellegrin, M, Laurenzi, A, Bonfanti, R, Battaglia, M, Bosi, E, Petrelli, A, Giovenzana A., Vecchio F., Cugnata F., Nonis A., Mandelli A., Stabilini A., Mazzi B. A., De Pellegrin M., Laurenzi A., Bonfanti R., Battaglia M., Bosi E., and Petrelli A.

Abstract

Aims: Alterations of the exocrine pancreas have been reported in type 1 diabetes, but their contribution to the pathogenesis of the disease is poorly understood. Here, we investigated markers of exocrine pancreas dysfunction in individuals at-risk of developing type 1 diabetes. Methods: Serum P-amylase and lipase levels were assessed in samples obtained from healthy controls, patients with new onset type 1 diabetes, relatives participating to the TrialNet Pathway to Prevention who were, at blood collection, autoantibody negative or positive for a single autoantibody (low-risk individuals), and positive for multiple autoantibodies (high-risk individuals). Linear mixed models were adopted to estimate variation of pancreatic enzymes among the groups and to evaluate the influence of high-risk HLA genotypes and residual beta cell function on exocrine pancreas function. Results: In adults, but not children, reduced levels of P-amylase and lipase were shown in at-risk individuals, including (for P-amylase levels only) those at low-risk, and in T1Dnew. Furthermore, while high-risk HLA genotypes negatively affected P-amylase levels in autoantibody negative adult individuals, fasting C-peptide levels did not correlate with pancreatic enzyme levels. Conclusions: Exocrine pancreas dysfunction precedes the onset of type 1 diabetes in adult at-risk individuals and may be unrelated to fasting C-peptide levels.

Published
2022

7. POS1418 ANTIGEN-SPECIFIC T-CELL DYNAMICS AND MULTIDIRECTIONAL IMMUNE DYSREGULATION IN SLE

Author

Ramirez, G. A., primary, Tassi, E., additional, Noviello, M., additional, Mazzi, B. A., additional, Moroni, L., additional, Sorce, A., additional, Citterio, L., additional, Zagato, L., additional, Tombetti, E., additional, Baldissera, E., additional, Colombo, G., additional, Yacoub, M. R., additional, Bozzolo, E., additional, Bonini, C., additional, Dagna, L., additional, and Manfredi, A., additional

Published
2023
Full Text
View/download PDF

8. Quantitative polymerase chain reaction-based chimerism in bone marrow or peripheral blood to predict acute myeloid leukemia relapse in high-risk patients: Results from the KIM-PB prospective study

Author

Gambacorta, V, Parolini, R, Xue, E, Greco, R, Bouwmans, E, Toffalori, C, Giglio, F, Assanelli, A, Stanghellini, M, Ambrosi, A, Mazzi, B, Mulder, W, Corti, C, Peccatori, J, Ciceri, F, Vago, L, Gambacorta V., Parolini R., Xue E., Greco R., Bouwmans E. E., Toffalori C., Giglio F., Assanelli A., Stanghellini M. T. L., Ambrosi A., Mazzi B., Mulder W., Corti C., Peccatori J., Ciceri F., Vago L., Gambacorta, V, Parolini, R, Xue, E, Greco, R, Bouwmans, E, Toffalori, C, Giglio, F, Assanelli, A, Stanghellini, M, Ambrosi, A, Mazzi, B, Mulder, W, Corti, C, Peccatori, J, Ciceri, F, Vago, L, Gambacorta V., Parolini R., Xue E., Greco R., Bouwmans E. E., Toffalori C., Giglio F., Assanelli A., Stanghellini M. T. L., Ambrosi A., Mazzi B., Mulder W., Corti C., Peccatori J., Ciceri F., and Vago L.

Published
2021

11. A Novel Assay in Whole Blood Demonstrates Restoration of Mitochondrial Activity in Phagocytes After Successful HSCT in Hyperinflamed X-Linked Chronic Granulomatous Disease

Author

Migliavacca, M., Basso Ricci, L., Farinelli, G., Calbi, V., Tucci, F., Barzaghi, F., Ferrua, F., Cicalese, M. P., Darin, S., Barzaghi, L. R., Giglio, F., Peccatori, J., Fumagalli, F., Nicoletti, R., Giannelli, S., Sartirana, C., Bandiera, A., Esposito, M., Milani, R., Mazzi, B., Finocchi, A., Marktel, S., Assanelli, A., Locatelli, Franco, Ciceri, F., Aiuti, A., Bernardo, M. E., Locatelli F. (ORCID:0000-0002-7976-3654), Migliavacca, M., Basso Ricci, L., Farinelli, G., Calbi, V., Tucci, F., Barzaghi, F., Ferrua, F., Cicalese, M. P., Darin, S., Barzaghi, L. R., Giglio, F., Peccatori, J., Fumagalli, F., Nicoletti, R., Giannelli, S., Sartirana, C., Bandiera, A., Esposito, M., Milani, R., Mazzi, B., Finocchi, A., Marktel, S., Assanelli, A., Locatelli, Franco, Ciceri, F., Aiuti, A., Bernardo, M. E., and Locatelli F. (ORCID:0000-0002-7976-3654)

Abstract

X-linked chronic granulomatous disease is a rare disease caused by mutations in the CYBB gene. While more extensive knowledge is available on genetics, pathogenesis, and possible therapeutic options, mitochondrial activity and its implications on patient monitoring are still not well-characterized. We have developed a novel protocol to study mitochondrial activity on whole blood of XCGD patients before and after transplantation, as well as on XCGD carriers. Here we present results of these analyses and of the restoration of mitochondrial activity in hyperinflamed X-linked Chronic Granulomatous Disease after hematopoietic stem cell transplantation. Moreover, we show a strong direct correlation between mitochondrial activity, chimerism, and DHR monitored before and after transplantation and in XCGD carriers. In conclusion, based on these findings, we suggest testing this new ready-to-use marker to better characterize patients before and after treatment and to investigate disease expression in carriers.

Published
2022

13. Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation

Author

Crucitti, L, Crocchiolo, R, Toffalori, C, Mazzi, B, Greco, R, Signori, A, Sizzano, F, Chiesa, L, Zino, E, Lupo Stanghellini, M T, Assanelli, A, Carrabba, M G, Marktel, S, Marcatti, M, Bordignon, C, Corti, C, Bernardi, M, Peccatori, J, Bonini, C, Fleischhauer, K, Ciceri, F, and Vago, L

Published
2015
Full Text
View/download PDF

14. Use of DPB1 T-cell epitope algorithm among italian transplant centers: A survey on behalf of Associazione Italiana di Immunogenetica e Biologia dei Trapianti

Author

Crocchiolo, R., Mele, L., Testi, M., Scollo Chiara, M., Murgia, B., Rossi, A., Vecchiato, C., Grammatico, P., Mininni, D., Longhi, E., Manfroi, S., Giuliodori, S., Castellani, L., Carella, G., Lai, S., Azzaro Maria, P., Mazzi, B., Perotti, L., Penta, R., Lombardo, C., Tognellini, R., Andreani, M., Albergoni Maria, P., Nesci, S., Cappuzzo, V., Chiusolo, Patrizia, Garino, E., Cappucci, G., Ceschini, N., Bevilacqua, E., Guizzardi, E., Tagliaferri Cinzia, M., Piazza, A., Carcassi, C., Miotti, V., Chiusolo P. (ORCID:0000-0002-1355-1587), Crocchiolo, R., Mele, L., Testi, M., Scollo Chiara, M., Murgia, B., Rossi, A., Vecchiato, C., Grammatico, P., Mininni, D., Longhi, E., Manfroi, S., Giuliodori, S., Castellani, L., Carella, G., Lai, S., Azzaro Maria, P., Mazzi, B., Perotti, L., Penta, R., Lombardo, C., Tognellini, R., Andreani, M., Albergoni Maria, P., Nesci, S., Cappuzzo, V., Chiusolo, Patrizia, Garino, E., Cappucci, G., Ceschini, N., Bevilacqua, E., Guizzardi, E., Tagliaferri Cinzia, M., Piazza, A., Carcassi, C., Miotti, V., and Chiusolo P. (ORCID:0000-0002-1355-1587)

Abstract

The HLA-DPB1 locus has been demonstrated to have a significant role on patients' outcome after allogeneic HSCT, and the so-called T-cell epitope (TCE) algorithm has been incorporated in international guidelines for the selection of unrelated donors. The purpose of the present study is to measure, through a national survey conducted on behalf of the Associazione Italiana di Immunogenetica e Biologia dei Trapianti (AIBT), the extent of awareness and use of HLA-DPB1 TCE-based algorithms during the donor search. 89% of the HLA laboratories answered to a short questionnaire and the results showed a progressive increase of the laboratories typing DPB1 in patients and their potential donors during the search (from 44% to 79% during the 2010–2019 period) as well as the application of a TCE-based algorithm for the donor choice whenever possible (from 24% to 65% during the same period). The DP-permissiveness status is detailed in the official HLA typing report by 12%, 32% and 50% of laboratories in 2010, 2015 and 2019, respectively. The present data indicate an encouraging raise in the awareness of the HLA-DPB1 role in unrelated donor selection; noteworthy, mentioning the TCE-based permissiveness status in the HLA typing report of each potential unrelated donor represents a notable mean to raise awareness among transplant physicians and to support them in their task of choosing the best donor. Nonetheless, despite the compelling evidence of the predictive ability of TCE-based algorithms, further efforts are still needed to extend its application to all transplant centers in Italy.

Published
2021

22. Genotypes and haplotypes in the 3′ untranslated region of the HLA-G gene and their association with clinical outcome of hematopoietic stem cell transplantation for beta-thalassemia

Author

Sizzano, F., Testi, M., Zito, L., Crocchiolo, R., Troiano, M., Mazzi, B., Turchiano, G., Torchio, M., Pultrone, C., Gregori, S., Chiesa, R., Gaziev, J., Sodani, P., Marktel, S., Amoroso, A., Roncarolo, M. G., Lucarelli, G., Ciceri, F., Andreani, M., and Fleischhauer, K.

Published
2012
Full Text
View/download PDF

32. DROPLET DIGITAL PCR FOR DNMT3A AND IDH1/2 MUTATIONS TO IMPROVE EARLY DETECTION OF ACUTE MYELOID LEUKEMIA RELAPSE AFTER ALLOGENEIC HSCT

Author

Brambati C, Galbiati S, Xue E, Toffalori C, Crucitti L, Greco R, Crippa A, Chiesa L, Soriani N, Mazzi B, Tresoldi C, Peccatori J, Carrabba MG, Bernardi M, Ferrari M, Lampasona V, Ciceri F, Vago L, Brambati, C, Xue, E, Toffalori, C, Galbiati, S, Crucitti, L, Greco, R, Crippa, A, Chiesa, L, Soriani, N, Mazzi, B, Tresoldi, C, Peccatori, J, Carrabba, Mg, Bernardi, M, Ferrari, M, Lampasona, V, Ciceri, F, and Vago, L

Published
2015

34. Serum antibodies against the insulin-like growth factor-1 receptor (IGF-1R) in Graves’ disease and Graves’ orbitopathy

Author

Marinò, M., primary, Rotondo Dottore, G., additional, Ionni, I., additional, Lanzolla, G., additional, Sabini, E., additional, Ricci, D., additional, Sframeli, A., additional, Mazzi, B., additional, Menconi, F., additional, Latrofa, F., additional, Vitti, P., additional, Marcocci, C., additional, and Chiovato, L., additional

Published
2018
Full Text
View/download PDF

36. NON-LINEAR CLONAL EVOLUTION OF LEUKEMIA DRIVEN BY THE SELECTIVE IMMUNE PRESSURE OF ALLOGENEIC HSCT

Author

Vago L, Cittaro D, Lazarevic D, Alori T, Oliveira G, Brambati C, Chiesa L, Mazzi B, Ponzoni M, Carrabba M, Bernardi M, Peccatori J, Bordignon C, Bonini C, Fleischhauer K, Ciceri F, Stupka E, Vago, L, Cittaro, D, Lazarevic, D, Toffalori, C, Oliveira, G, Brambati, C, Chiesa, L, Mazzi, B, Ponzoni, M, Carrabba, M, Bernardi, M, Peccatori, J, Bordignon, C, Bonini, C, Fleischhauer, K, Ciceri, F, Stupka, E, and Alori, T

Published
2014

37. Droplet Digital PCR for DNMT3A and IDH1/2 Mutations to Improve Early Diagnosis of Acute Myeloid Leukemia Relapse after Allogeneic HSCT

Author

Brambati C, Toffalori C, Xue E, Crucitti L, Greco R, Crippa A, Mazzi B, Tresoldi C, Galbiati S, Bonini C, Peccatori J, Carrabba MG, Bernardi M, Ferrari M, Lampasona V, Ciceri F, Vago L, Brambati, C, Toffalori, C, Xue, E, Crucitti, L, Greco, R, Crippa, A, Mazzi, B, Tresoldi, C, Galbiati, S, Bonini, C, Peccatori, J, Carrabba, Mg, Bernardi, M, Ferrari, M, Lampasona, V, Ciceri, F, and Vago, L

Published
2014

39. Use of low-dose radioiodine ablation for Graves’ orbitopathy: results of a pilot, perspective study in a small series of patients

Author

Leo, M., primary, Sabini, E., additional, Ionni, I., additional, Sframeli, A., additional, Mazzi, B., additional, Menconi, F., additional, Molinaro, E., additional, Bianchi, F., additional, Brozzi, F., additional, Santini, P., additional, Elisei, R., additional, Nardi, M., additional, Vitti, P., additional, Marcocci, C., additional, and Marinò, M., additional

Published
2017
Full Text
View/download PDF

40. Incidence, Risk Factors and Clinical Outcome Of Leukemia Relapses Due To Loss Of The Mismatched HLA Haplotype After Partially-Incompatible Hematopoietic Stem Cell Transplantation

Author

Crucitti L, Crocchiolo R, Toffalori C, Stanghellini MTL, Assanelli A, Carrabba M, Mazzi B, Zino E, Marktel S, Marcatti M, Corti C, Bernardi M, Peccatori J, Bordignon C, Bonini C, Fleischhauer K, Ciceri F, Vago L, Crucitti, L, Crocchiolo, R, Toffalori, C, Stanghellini, Mtl, Assanelli, A, Carrabba, M, Mazzi, B, Zino, E, Marktel, S, Marcatti, M, Corti, C, Bernardi, M, Peccatori, J, Bordignon, C, Bonini, C, Fleischhauer, K, Ciceri, F, and Vago, L

Published
2013

41. Loss of mismatched HLA at leukaemia relapse after haematopoietic stem cell transplantation is significantly associated with clinical and immunogenetic hallmarks of donor-versus-host alloreactivity

Author

Crucitti L, Crocchiolo R, Toffalori C, Stanghellini MTL, Assanelli A, Carrabba M, Mazzi B, Zino E, Marktel S, Marcatti M, Corti C, Bernardi M, Peccatori J, Bordignon C, Bonini C, Fleischhauer K, Ciceri F, Vago L, Crucitti, L, Crocchiolo, R, Toffalori, C, Stanghellini, Mtl, Assanelli, A, Carrabba, M, Mazzi, B, Zino, E, Marktel, S, Marcatti, M, Corti, C, Bernardi, M, Peccatori, J, Bordignon, C, Bonini, C, Fleischhauer, K, Ciceri, F, and Vago, L

Published
2013

42. High-Sensitivity Hematopoietic Chimerism By qPCR For Relapse Prediction and Specific Identification Of HLA Loss Leukemic Variants

Author

Vago L, Mazzi B, Chiesa L, Greco R, Pultrone C, Toffoletti E, Toffalori C, Crivello P, Tettamanzi V, Crucitti L, Stanghellini MTL, Assanelli A, Corti C, Bernardi M, Peccatori J, Bonini C, Bost DA, Ciceri F, Fleischhauer K, Vago, L, Mazzi, B, Chiesa, L, Greco, R, Pultrone, C, Toffoletti, E, Toffalori, C, Crivello, P, Tettamanzi, V, Crucitti, L, Stanghellini, Mtl, Assanelli, A, Corti, C, Bernardi, M, Peccatori, J, Bonini, C, Bost, Da, Ciceri, F, and Fleischhauer, K

Published
2013

43. Non-Linear Clonal Evolution Of Leukemia Driven By Selective Immune Pressure and Revealed By HLA Typing and High-Depth Exome Sequencing

Author

Vago L, Cittaro D, Lazarevic D, Toffalori C, Oliveira G, Chiesa L, Mazzi B, Ponzoni M, Carrabba M, Bernardi M, Peccatori J, Bordignon C, Bonini C, Fleischhauer K, Ciceri F, Stupka E, Vago, L, Cittaro, D, Lazarevic, D, Toffalori, C, Oliveira, G, Chiesa, L, Mazzi, B, Ponzoni, M, Carrabba, M, Bernardi, M, Peccatori, J, Bordignon, C, Bonini, C, Fleischhauer, K, Ciceri, F, and Stupka, E

Published
2013

46. Loss of Mismatched HLA At Leukemia Relapse After Hematopoietic Stem Cell Transplantation Is Significantly Associated with Clinical and Immunogenetic Hallmarks of Donor-Versus-Host Alloreactivity

Author

Crucitti L, Crocchiolo R, Toffalori C, Stanghellini MTL, Assanelli A, Carrabba M, Mazzi B, Zino E, Marktel S, Marcatti M, Consuelo C, Bernardi M, Peccatori J, Bordignon C, Bonini C, Fleischhauer K, Ciceri F, Vago L, Crucitti, L, Vago, L, Crocchiolo, R, Toffalori, C, Stanghellini, Mtl, Assanelli, A, Carrabba, M, Mazzi, B, Zino, E, Marktel, S, Marcatti, M, Corti, C, Bernardi, M, Peccatori, J, Bordignon, C, Bonini, C, Fleischhauer, K, Ciceri, F, and Consuelo, C

Published
2012

49. Loss of mismatched HLA as a mechanism of leukaemia immune escape in family haploidentical and unrelated haematopoietic stem cell transplantation

Author

Vago L, Stanghellini MTL, Clerici D, Crotta A, Messina C, Forno B, Mazzi B, Zanussi M, Turchiano G, Marcatti M, Corti C, Bernardi M, Peccatori J, Rossini S, FERRARI, MAURIZIO, Fleischhauer K, BORDIGNON, CLAUDIO, BONINI , MARIA CHIARA, CICERI, FABIO, Vago, L, Stanghellini, Mtl, Clerici, D, Crotta, A, Messina, C, Forno, B, Mazzi, B, Zanussi, M, Turchiano, G, Marcatti, M, Corti, C, Bernardi, M, Peccatori, J, Rossini, S, Ferrari, Maurizio, Bordignon, Claudio, Bonini, MARIA CHIARA, Fleischhauer, K, and Ciceri, Fabio

Published
2010

50. Timing and rate of success in transplant of matched unrelated donor (MUD) searches through bone marrow donors worldwide (BMDW): the case of San Raffaele Institute in 2006-2009

Author

Forno B, Mazzi B, Zino E, Lupo Stanghellini MT, Vago L, Guggiari E, Coppola M, Piemontese S, Claudiani S, Lunghi F, Marktel S, Bernardi M, Corti C, Peccatori J, CICERI, FABIO, Fleischhauer K, Marcatti M., BONINI , MARIA CHIARA, Forno, B, Mazzi, B, Zino, E, Lupo Stanghellini, Mt, Vago, L, Guggiari, E, Coppola, M, Piemontese, S, Claudiani, S, Lunghi, F, Marktel, S, Bernardi, M, Corti, C, Bonini, MARIA CHIARA, Peccatori, J, Ciceri, Fabio, Fleischhauer, K, and Marcatti, M.

Published
2010

Catalog

Books, media, physical & digital resources
See catalog results