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225 results on '"Mazzeo, Pietro"'

1. The effects of Dapagliflozin in a real-world population of HFrEF patients with different hemodynamic profiles: worse is better

Author

Loria, Francesco, Mone, Pasquale, Rispoli, Antonella, Di Fonzo, Rosanna, Masarone, Daniele, Mancusi, Costantino, Correale, Michele, Vitullo, Antonio, Granatiero, Michele, Mazzeo, Pietro, Mercurio, Valentina, Fiore, Francesco, Di Sarro, Elena, Falco, Luigi, Izzo, Carmine, Campanile, Alfonso, Virtuoso, Nicola, Stabile, Eugenio, Bonanno, Salvatore, Dattilo, Giuseppe, Tocchetti, Carlo Gabriele, Santulli, Gaetano, Vecchione, Carmine, Ciccarelli, Michele, and Visco, Valeria

Published
2024
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8. The Italian version of the quick mild cognitive impairment (Qmci-I) screen: normative study on 307 healthy subjects

Author

Iavarone, Alessandro, Carpinelli Mazzi, Michele, Russo, Gennaro, D’Anna, Francesco, Peluso, Silvio, Mazzeo, Pietro, De Luca, Vincenzo, De Michele, Giuseppe, Iaccarino, Guido, Abete, Pasquale, Milan, Graziella, Garofalo, Elisabetta, Musella, Caterina, O’Caoimh, Rónán, Molloy, William, De Joanna, Gabriella, Manzo, Valentino, Ambra, Ferdinando Ivano, Postiglione, Alfredo, Illario, Maddalena, and the Working Group

Published
2019
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9. Switch to gliflozins and biventricular function improvement in patients with chronic heart failure and diabetes mellitus

Author

Correale, Michele, primary, Mazzeo, Pietro, additional, Fortunato, Martino, additional, Paradiso, Matteo, additional, Furore, Andrea, additional, Fanizzi, Angela I., additional, Tricarico, Lucia, additional, Pastore, Giuseppe, additional, Alfieri, Simona, additional, Brunetti, Natale D., additional, and Lamacchia, Olga, additional

Published
2023
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11. Switch to gliflozins and biventricular function improvement in patients with chronic heart failure and diabetes mellitus.

Author

Correale, Michele, Mazzeo, Pietro, Fortunato, Martino, Paradiso, Matteo, Furore, Andrea, Fanizzi, Angela I., Tricarico, Lucia, Pastore, Giuseppe, Alfieri, Simona, Brunetti, Natale D., and Lamacchia, Olga

Subjects
*HEART failure patients, *DIABETES, *TRICUSPID valve insufficiency, *SODIUM-glucose cotransporter 2 inhibitors, *PEOPLE with diabetes
Abstract

Background: SGLT2 inhibitors have been shown to reduce hospitalisation in patients with chronic heart failure (CHF). The cardioprotective mechanisms of gliflozins however have not been fully elucidated. The aim of this study was therefore to evaluate the effect of SGLT2 inhibitors on right and left ventricular function in patients with diabetes and HF. Methods: Seventy‐eight patients with diabetes and CHF were enroled in the study and followed up; 38 started treatment with SGLT2i, while the remaining 40 continued their previous antidiabetic therapy. All patients underwent conventional, TDI and strain echocardiography in an ambulatory setting, at the beginning and after 3 months of therapy with SGLT2i. Results: After 3 months of therapy with SGLT2i, echocardiographic parameters assessing both left and right ventricular dimensions and function were found as significantly improved in patients switching to SGLT2i than control group: LVEF (45 ± 9% vs. 40 ± 8%, p < 0.001), LVEDD (54 ± 6.5 vs. 56 ± 6.5 mm, p < 0.01), GLS (−13 ± 4% vs. −10 ± 3%, p < 0.001), TAPSE (21 ± 3 vs. 19 ± 3 mm, p < 0.001), RV S' (12.9 ± 2.5 vs 11.0 ± 1.9 cm/sec, p < 0.001) and PAsP (24 ± 8 vs. 31 ± 9 mmHg, p < 0.001). Also mitral (1.0 ± 0.5 vs. 1.3 ± 0.5, p < 0.01) and tricuspid regurgitation (1.0 ± 0.5 vs. 1.3 ± 0.5, p < 0.01) improved after SGLT2i therapy. Changes were not statistically significant in patients not treated with SGLT2i (p n.s. in all cases). Conclusions: In a real‐world scenario, treatment with SGLT2i in patients with CHF and diabetes is associated with an improvement in both left and right ventricular function assessed at echocardiography. These data may explain potential anti‐remodelling effects of gliflozins. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Left Atrial Functional Remodeling in Patients with Chronic Heart Failure Treated with Sacubitril/Valsartan

Author

Correale, Michele, primary, Magnesa, Michele, additional, Mazzeo, Pietro, additional, Fortunato, Martino, additional, Tricarico, Lucia, additional, Leopizzi, Alessandra, additional, Mallardi, Adriana, additional, Mennella, Raffaele, additional, Croella, Francesca, additional, Iacoviello, Massimo, additional, Di Biase, Matteo, additional, and Brunetti, Natale Daniele, additional

Published
2023
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15. 782 RATIONALE AND DESIGN OF EFI-CHF (ENDOTHELIAL FUNCTION IN PATIENTS WITH CHRONIC HEART FAILURE TREATED BY SGLT2I)STUDY

Author

Di Nunno, Nicola, primary, D´alessandro, Damiano, additional, Granatiero, Michele, additional, Tricarico, Lucia, additional, Mazzeo, Pietro, additional, Ceci, Vincenzo, additional, Amatruda, Marco, additional, Pugliese, Rosanna, additional, Alfieri, Simona, additional, Croella, Francesca, additional, Mallardi, Adriana, additional, Leopizzi, Alessandra, additional, Correale, Michele, additional, Iacoviello, Massimo, additional, Di Biase, Matteo, additional, Stabile, Eugenio, additional, and Brunetti, Natale D, additional

Published
2022
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16. 39 ECHOCARDIOGRAPHIC FINDING BETWEEN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION IN TREATMENT WITH ARNI AND SGLT2I

Author

Ceci, Vincenzo, primary, Mazzeo, Pietro, additional, Ferrara, Salvatore, additional, Nardella, Luigi, additional, Tricarico, Lucia, additional, Alfieri, Simona, additional, Croella, Francesca, additional, Amatruda, Marco, additional, Granatiero, Michele, additional, D´alessandro, Damiano, additional, Di Nunno, Nicola, additional, Pugliese, Rosanna, additional, Noviello, Giulia, additional, Correale, Michele, additional, Stabile, Egenio, additional, Stabile, Eugenio, additional, Iacoviello, Massimo, additional, Di Biase, Matteo, additional, and Brunetti, Natale D, additional

Published
2022
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17. Deformation Imaging by Strain in Chronic Heart Failure Over Sacubitril‐Valsartan: A Multicenter Echocardiographic Registry

Author

Mandoli, Giulia Elena, primary, Pastore, Maria Concetta, additional, Giannoni, Alberto, additional, Benfari, Giovanni, additional, Dini, Frank Lloyd, additional, Rosa, Gianmarco, additional, Pugliese, Nicola Riccardo, additional, Taddei, Claudia, additional, Correale, Michele, additional, Brunetti, Natale Daniele, additional, Mazzeo, Pietro, additional, Carluccio, Erberto, additional, Mengoni, Anna, additional, Guaricci, Andrea Igoren, additional, Piscitelli, Laura, additional, Citro, Rodolfo, additional, Ciccarelli, Michele, additional, Novo, Giuseppina, additional, Corrado, Egle, additional, Pasquini, Annalisa, additional, Loria, Valentina, additional, De Carli, Giuseppe, additional, Degiovanni, Anna, additional, Patti, Giuseppe, additional, Santoro, Ciro, additional, Moderato, Luca, additional, Cicoira, Mariantonietta, additional, Canepa, Marco, additional, Malagoli, Alessandro, additional, Emdin, Michele, additional, and Cameli, Matteo, additional

Published
2022
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19. Sacubitril/valsartan reduces indications for arrhythmic primary prevention in heart failure with reduced ejection fraction: insights from DISCOVER-ARNI, a multicenter Italian register

Author

Pastore, Maria Concetta, Mandoli, Giulia Elena, Giannoni, Alberto, Benfari, Giovanni, Dini, Frank Lloyd, Pugliese, Nicola Riccardo, Taddei, Claudia, Correale, Michele, Brunetti, Natale Daniele, Carluccio, Erberto, Mengoni, Anna, Guaricci, Andrea Igoren, Piscitelli, Laura, Citro, Rodolfo, Ciccarelli, Michele, Novo, Giuseppina, Corrado, Egle, Pasquini, Annalisa, Loria, Valentina, Degiovanni, Anna, Patti, Giuseppe, Santoro, Ciro, Moderato, Luca, Malagoli, Alessandro, Emdin, Michele, Cameli, Matteo, Rosa, Gianmarco, Magnesa, Michele, Mazzeo, Pietro, De Carli, Giuseppe, Bellino, Michele, Iuliano, Giuseppe, Casciano, Ofelia, Binno, Simone, Canepa, Marco, Tondi, Stefano, Cicoira, Mariantonietta, Mega, Simona, Pastore, Maria Concetta, Mandoli, Giulia Elena, Giannoni, Alberto, Benfari, Giovanni, Dini, Frank Lloyd, Pugliese, Nicola Riccardo, Taddei, Claudia, Correale, Michele, Brunetti, Natale Daniele, Carluccio, Erberto, Mengoni, Anna, Guaricci, Andrea Igoren, Piscitelli, Laura, Citro, Rodolfo, Ciccarelli, Michele, Novo, Giuseppina, Corrado, Egle, Pasquini, Annalisa, Loria, Valentina, Degiovanni, Anna, Patti, Giuseppe, Santoro, Ciro, Moderato, Luca, Malagoli, Alessandro, Emdin, Michele, Cameli, Matteo, Rosa, Gianmarco, Magnesa, Michele, Mazzeo, Pietro, De Carli, Giuseppe, Bellino, Michele, Iuliano, Giuseppe, Casciano, Ofelia, Binno, Simone, Canepa, Marco, Tondi, Stefano, Cicoira, Mariantonietta, and Mega, Simona

Subjects
Left ventricular strain, Heart failure, Implantable cardioverter-defibrillator, Remodelling, Sacubitril/valsartan, Heart failure, Implantable cardioverter-defibrillator, Left ventricular strain, Remodelling, Sacubitril/valsartan
Abstract

Aims This sub-study deriving from a multicentre Italian register [Deformation Imaging by Strain in Chronic Heart Failure Over Sacubitril-Valsartan: A Multicenter Echocardiographic Registry (DISCOVER)-ARNI] investigated whether sacubitril/valsartan in addition to optimal medical therapy (OMT) could reduce the rate of implantable cardioverter-defibrillator (ICD) indications for primary prevention in heart failure with reduced ejection fraction (HFrEF) according to European guidelines indications, and its potential predictors. Methods and results In this observational study, consecutive patients with HFrEF eligible for sacubitril/valsartan from 13 Italian centres were included. Lack of follow-up or speckle tracking data represented exclusion criteria. Demographic, clinical, biochemical, and echocardiographic data were collected at baseline and after 6 months from sacubitril/valsartan initiation. Of 351 patients, 225 (64%) were ICD carriers and 126 (36%) were not ICD carriers (of whom 13 had no indication) at baseline. After 6 months of sacubitril/valsartan, among 113 non-ICD carriers despite having baseline left ventricular (LV) ejection fraction (EF) ≤ 35% and New York Heart Association (NYHA) class = II–III, 69 (60%) did not show ICD indications; 44 (40%) still fulfilled ICD criteria. Age, atrial fibrillation, mitral regurgitation > moderate, left atrial volume index (LAVi), and LV global longitudinal strain (GLS) significantly varied between the groups. With receiver operating characteristic curves, age ≥ 75 years, LAVi ≥ 42 mL/m2 and LV GLS ≥−8.3% were associated with ICD indications persistence (area under the curve = 0.65, 0.68, 0.68, respectively). With univariate and multivariate analysis, only LV GLS emerged as significant predictor of ICD indications at follow-up in different predictive models. Conclusions Sacubitril/valsartan may provide early improvement of NYHA class and LVEF, reducing the possible number of implanted ICD for primary prevention in HFrEF. Baseline reduced LV GLS was a strong marker of ICD indication despite OMT. Early therapy with sacubitril/valsartan may save infective/haemorrhagic risks and unnecessary costs deriving from ICDs.

Published
2022

20. Rationale and design of the Biventricular Evaluation of Gliflozins effects In chroNic Heart Failure: BEGIN‐HF study.

Author

Correale, Michele, Antohi, Elena‐Laura, Inciardi, Riccardo M., Mazzeo, Pietro, Coiro, Stefano, Ishihara, Shiro, Petroni, Renata, Monitillo, Francesco, Leone, Marta, Triggiani, Marco, Sarwar, Chaudhry M.S., Dungen, Hans‐Dirk, Talha, Khawaja M., Brunetti, Natale D., Butler, Javed, and Nodari, Savina

Subjects
SODIUM-glucose cotransporters, SPECKLE tracking echocardiography, HEART failure, SODIUM-glucose cotransporter 2 inhibitors, ECHOCARDIOGRAPHY, TYPE 2 diabetes
Abstract

Aims: Sodium‐glucose cotransporter type 2 inhibitors (SGLT‐2i) represent a unique class of anti‐hyperglycaemic agents for type 2 diabetes mellitus that selectively inhibit renal glucose reabsorption, thereby increasing urinary excretion of glucose. Several studies have demonstrated the cardioprotective effects of SGLT‐2i in patients with heart failure (HF), unrelated to its glucosuric effect. It is unclear whether the benefits of SGLT‐2i therapy also rely on the improvement of left ventricular (LV) and/or right ventricular (RV) function in patients with HF. This study aimed to evaluate the effect of SGLT‐2i on LV and RV function through conventional and advanced echocardiographic parameters with a special focus on RV function in patients with HF. Methods and results: The Biventricular Evaluation of Gliflozins effects In chroNic Heart Failure (BEGIN‐HF) study is an international multicentre, prospective study that will evaluate the effect of SGLT‐2i on echocardiographic parameters of myocardial function in patients with chronic stable HF across the left ventricular ejection fraction (LVEF) spectrum. Patients with New York Heart Association Class II/III symptoms, estimated glomerular filtration rate > 25 mL/min/1.73 m2, age > 18 years, and those who were not previously treated with SGLT‐2i will be included. All patients will undergo conventional, tissue‐derived imaging (TDI), and strain echocardiography in an ambulatory setting, at time of enrolment and after 6 months of SGLT‐2i therapy. The primary endpoint is the change in LV function as assessed by conventional, TDI, and myocardial deformation speckle tracking parameters. Secondary outcomes include changes in RV and left atrial function as assessed by conventional and deformation speckle tracking echocardiography. Univariate and multivariate analyses will be performed to identify predictors associated with primary and secondary endpoints. Conclusions: The BEGIN‐HF will determine whether SGLT‐2i therapy improves LV and/or RV function by conventional and advanced echocardiography in patients with HF irrespective of LVEF. [ABSTRACT FROM AUTHOR]

Published
2023
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21. Predictors of sacubitril/valsartan high dose tolerability in a real world population with HFrEF

Author

Visco, Valeria, primary, Radano, Ilaria, additional, Campanile, Alfonso, additional, Ravera, Amelia, additional, Silverio, Angelo, additional, Masarone, Daniele, additional, Pacileo, Giuseppe, additional, Correale, Michele, additional, Mazzeo, Pietro, additional, Dattilo, Giuseppe, additional, Giallauria, Francesco, additional, Cuomo, Alessandra, additional, Mercurio, Valentina, additional, Tocchetti, Carlo Gabriele, additional, Di Pietro, Paola, additional, Carrizzo, Albino, additional, Citro, Rodolfo, additional, Galasso, Gennaro, additional, Vecchione, Carmine, additional, and Ciccarelli, Michele, additional

Published
2022
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22. Deformation Imaging by Strain in Chronic Heart Failure Over Sacubitril‐Valsartan: A Multicenter Echocardiographic Registry.

Author

Mandoli, Giulia Elena, Pastore, Maria Concetta, Giannoni, Alberto, Benfari, Giovanni, Dini, Frank Lloyd, Rosa, Gianmarco, Pugliese, Nicola Riccardo, Taddei, Claudia, Correale, Michele, Brunetti, Natale Daniele, Mazzeo, Pietro, Carluccio, Erberto, Mengoni, Anna, Guaricci, Andrea Igoren, Piscitelli, Laura, Citro, Rodolfo, Ciccarelli, Michele, Novo, Giuseppina, Corrado, Egle, and Pasquini, Annalisa

Subjects
SPECKLE tracking echocardiography, BRAIN natriuretic factor, GLOBAL longitudinal strain, HEART failure, ECHOCARDIOGRAPHY, ENTRESTO
Abstract

Aims: Sacubitril/valsartan has changed the treatment of heart failure with reduced ejection fraction (HFrEF), due to the positive effects on morbidity and mortality, partly mediated by left ventricular (LV) reverse remodelling (LVRR). The aim of this multicenter study was to identify echocardiographic predictors of LVRR after sacubitril/valsartan administration. Methods and results: Patients with HFrEF requiring therapy with sacubitril/valsartan from 13 Italian centres were included. Echocardiographic parameters including LV global longitudinal strain (GLS) and global peak atrial longitudinal strain by speckle tracking echocardiography were measured to find the predictors of LVRR [= LV end‐systolic volume reduction ≥10% and ejection fraction (LVEF) improvement ≥10% at follow‐up] at 6 month follow‐up as the primary endpoint. Changes in symptoms [New York Heart Association (NYHA) class] and neurohormonal activations [N‐terminal pro‐brain natriuretic peptide (NT‐proBNP)] were also evaluated as secondary endpoints; 341 patients (excluding patients with poor acoustic windows and missing data) were analysed (mean age: 65 ± 10 years; 18% female, median LVEF 30% [inter‐quartile range: 25−34]). At 6 month follow‐up, 82 (24%) patients showed early complete response (LVRR and LVEF ≥ 35%), 55 (16%) early incomplete response (LVRR and LVEF < 35%), and 204 (60%) no response (no LVRR and LVEF < 35%). Non‐ischaemic aetiology, a lower left atrial volume index, and a higher GLS were all independent predictors of LVRR at multivariable logistic analysis (all P < 0.01). A baseline GLS < −9.3% was significantly associated with early response (area under the curve 0.75, P < 0.0001). Left atrial strain was the best predictor of positive changes in NYHA class and NT‐proBNP (all P < 0.05). Conclusions: Speckle tracking echocardiography parameters at baseline could be useful to predict LVRR and clinical response to sacubitril–valsartan and could be used as a guide for treatment in patients with HFrEF. [ABSTRACT FROM AUTHOR]

Published
2023
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23. 24 Gliflozins and ventricular function in patients affected by chronic heart failure with diabetes mellitus

Author

Fortunato, Martino, primary, Mazzeo, Pietro, additional, Correale, Michele, additional, Paradiso, Matteo, additional, Furore, Andrea, additional, Fanizzi, Angela Ilaria, additional, Tricarico, Lucia, additional, Maiellaro, Pasquale, additional, Pastore, Giuseppe, additional, Alfieri, Simona, additional, Lamacchia, Olga, additional, Iacoviello, Massimo, additional, Biase, Matteo Di, additional, and Brunetti, Natale Daniele, additional

Published
2021
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24. 25 Atrial remodelling in patients affected by chronic heart failure in therapy with sacubitril/valsartan

Author

Magnesa, Michele, primary, Mazzeo, Pietro, additional, Fortunato, Martino, additional, Mennella, Raffaele, additional, Tricarico, Lucia, additional, Correale, Michele, additional, Croella, Francesca, additional, Mallardi, Adriana, additional, Leopizzi, Alessandra, additional, Ceci, Vincenzo, additional, Alfieri, Simona, additional, Iacoviello, Massimo, additional, Biase, Matteo Di, additional, and Brunetti, Natale Daniele, additional

Published
2021
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25. 62 Biventricular evaluation of gliflozines effects in chronic heart failure patients function (begin-HF study): an international registry

Author

Correale, Michele, primary, Mazzeo, Pietro, additional, Petroni, Renata, additional, Coiro, Stefano, additional, Antohi, Elena-Laura, additional, Monitillo, Francesco, additional, Leone, Marta, additional, Triggiani, Marco, additional, Dungen, Hans-Dirk, additional, Sarwar, Chaudhry M. S., additional, and Nodari, Savina, additional

Published
2021
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26. 61 Right ventricular function in patient with heart failure with reduced ejection fraction and sacubitril/valsartan treatment

Author

Mazzeo, Pietro, primary, Fortunato, Martino, additional, Croella, Francesca, additional, Alfieri, Simona, additional, Fanizzi, Angela Ilaria, additional, Furore, Andrea, additional, Ferrara, Salvatore, additional, Tricarico, Lucia, additional, Correale, Michele, additional, Iacoviello, Massimo, additional, Di Biase, Matteo, additional, and Brunetti, Natale D, additional

Published
2021
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27. 37 Prognostic role of the lung ultrasound in the acute coronary syndrome

Author

Tricarico, Lucia, primary, Persichella, Paola, additional, Mazzeo, Pietro, additional, Leopizzi, Alessandra, additional, Mallardi, Adriana, additional, Magnesa, Michele, additional, Fortunato, Martino, additional, Croella, Francesca, additional, Alfieri, Simona, additional, Correale, Michele, additional, Iacoviello, Massimo, additional, and Brunetti, Natale D, additional

Published
2021
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28. 63 Peripheral endothelial function in patients affected by pulmonary hypertension. Relationship between endothelial function, haemodynamic parameters, and therapy response

Author

Correale, Michele, primary, Tricarico, Lucia, additional, Croella, Francesca, additional, Fortunato, Martino, additional, Ceci, Vincenzo, additional, Mazzeo, Pietro, additional, Alfieri, Simona, additional, Iacoviello, Massimo, additional, Di Biase, Matteo, additional, and Brunetti, Natale D, additional

Published
2021
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29. 266 Deformation imaging by strain in chronic heart failure over sacubitril–valsartan: a multicentre echocardiographic registry (discover)—ARNI

Author

Mandoli, Giulia Elena, primary, Pastore, Maria Concetta, additional, Giannoni, Alberto, additional, Benfari, Giovanni, additional, Dini, Frank Lloyd, additional, Rosa, Gianmarco, additional, Pugliese, Nicola Riccardo, additional, Taddei, Claudia, additional, Correale, Michele, additional, Brunetti, Natale Daniele, additional, Mazzeo, Pietro, additional, Carluccio, Erberto, additional, Mengoni, Anna, additional, Guaricci, Andrea Igoren, additional, Piscitelli, Laura, additional, Citro, Rodolfo, additional, Ciccarelli, Michele, additional, Novo, Giuseppina, additional, Corrado, Egle, additional, Pasquini, Annalisa, additional, Loria, Valentina, additional, Carli, Giuseppe De, additional, Degiovanni, Anna, additional, Patti, Giuseppe, additional, Santoro, Ciro, additional, Moderato, Luca, additional, Cicoira, Mariantonietta, additional, Canepa, Marco, additional, Malagoli, Alessandro, additional, Emdin, Michele, additional, and Cameli, Matteo, additional

Published
2021
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32. Predictors of right ventricular function improvement with sacubitril/valsartan in a real‐life population of patients with chronic heart failure

Author

Correale, Michele, primary, Mazzeo, Pietro, additional, Magnesa, Michele, additional, Fortunato, Martino, additional, Tricarico, Lucia, additional, Leopizzi, Alessandra, additional, Mallardi, Adriana, additional, Mennella, Raffaele, additional, Tucci, Salvatore, additional, and Brunetti, Natale Daniele, additional

Published
2021
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33. Switch to SGLT2 Inhibitors and Improved Endothelial Function in Diabetic Patients with Chronic Heart Failure

Author

Correale, Michele, primary, Mazzeo, Pietro, additional, Mallardi, Adriana, additional, Leopizzi, Alessandra, additional, Tricarico, Lucia, additional, Fortunato, Martino, additional, Magnesa, Michele, additional, Tucci, Salvatore, additional, Maiellaro, Pasquale, additional, Pastore, Giuseppe, additional, Lamacchia, Olga, additional, Iacoviello, Massimo, additional, Di Biase, Matteo, additional, and Brunetti, Natale Daniele, additional

Published
2021
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34. Remodelling is inversely proportional to left ventricular dimensions in a real-life population of patients with chronic heart failure after therapy with sacubitril/valsartan

Author

Correale, Michele, primary, Mallardi, Adriana, additional, Tricarico, Lucia, additional, Mazzeo, Pietro, additional, Ferraretti, Armando, additional, Diella, Claudia, additional, Romano, Valentina, additional, Merolla, Giuseppina, additional, Iacoviello, Massimo, additional, Di Biase, Matteo, additional, and Brunetti, Natale Daniele, additional

Published
2021
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37. The Evolving Phenotypes of Cardiovascular Disease during COVID-19 Pandemic

Author

Correale, Michele, primary, Croella, Francesca, additional, Leopizzi, Alessandra, additional, Mazzeo, Pietro, additional, Tricarico, Lucia, additional, Mallardi, Adriana, additional, Fortunato, Martino, additional, Magnesa, Michele, additional, Ceci, Vincenzo, additional, Puteo, Alessandra, additional, Iacoviello, Massimo, additional, Di Biase, Matteo, additional, and Brunetti, Natale Daniele, additional

Published
2021
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38. Multivessel spontaneous coronary artery dissection and Crohn's disease

Author

Corbo, Maria Delia, primary, Centola, Antonio, additional, Fortunato, Martino, additional, Mazzeo, Pietro, additional, Vitale, Enrica, additional, Della Monica, Davide, additional, Magnesa, Michele, additional, Ieva, Riccardo, additional, Cuculo, Andrea, additional, Iacoviello, Massimo, additional, and Brunetti, Natale Daniele, additional

Published
2021
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39. New Targets in Heart Failure Drug Therapy

Author

Correale, Michele, primary, Tricarico, Lucia, additional, Fortunato, Martino, additional, Mazzeo, Pietro, additional, Nodari, Savina, additional, Di Biase, Matteo, additional, and Brunetti, Natale Daniele, additional

Published
2021
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45. Serum Uric Acid and Left Ventricular Mass in Essential Hypertension

Author

Visco, Valeria, primary, Pascale, Antonietta Valeria, additional, Virtuoso, Nicola, additional, Mongiello, Felice, additional, Cinque, Federico, additional, Gioia, Renato, additional, Finelli, Rosa, additional, Mazzeo, Pietro, additional, Manzi, Maria Virginia, additional, Morisco, Carmine, additional, Rozza, Francesco, additional, Izzo, Raffaele, additional, Cerasuolo, Federica, additional, Ciccarelli, Michele, additional, and Iaccarino, Guido, additional

Published
2020
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46. Liver disease and heart failure

Author

Correale, Michele, primary, Tricarico, Lucia, additional, Leopizzi, Alessandra, additional, Mallardi, Adriana, additional, Mazzeo, Pietro, additional, Tucci, Salvatore, additional, Grazioli, Davide, additional, Di Biase, Matteo, additional, and Brunetti, Natale D., additional

Published
2020
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49. The Italian version of the quick mild cognitive impairment (Qmci-I) screen: normative study on 307 healthy subjects

Author

Iavarone, Alessandro, Carpinelli Mazzi, Michele, Russo, Gennaro, D’Anna, Francesco, Peluso, Silvio, Mazzeo, Pietro, de Luca, Vincenzo, de Michele, Giuseppe, Iaccarino, Guido, Abete, Pasquale, Milan, Graziella, Garofalo, Elisabetta, Musella, Caterina, O’Caoimh, Rónán, Molloy, William, de Joanna, Gabriella, Manzo, Valentino, Ambra, Ferdinando Ivano, Postiglione, Alfredo, Illario, Maddalena, Arcopinto, Michele, Cuccaro, Patrizia, de Chiara, Simona, DE LUCIA, Natascia, Del Giudice, Carmine, Ferrara, Nicola, Girardi, Vincenzo, Grimaldi, Iolanda, Liguori, Ilaria, Pernas, Francesco Orfila, Paúl, Constança, TRAMONTANO, GIOVANNI, Tripodi, Francesca Saveria, Iavarone, Alessandro, Carpinelli Mazzi, Michele, Russo, Gennaro, D’Anna, Francesco, Peluso, Silvio, Mazzeo, Pietro, de Luca, Vincenzo, de Michele, Giuseppe, Iaccarino, Guido, Abete, Pasquale, Milan, Graziella, Garofalo, Elisabetta, Musella, Caterina, O’Caoimh, Rónán, Molloy, William, de Joanna, Gabriella, Manzo, Valentino, Ambra, Ferdinando Ivano, Postiglione, Alfredo, Illario, Maddalena, Arcopinto, Michele, Cuccaro, Patrizia, de Chiara, Simona, DE LUCIA, Natascia, Del Giudice, Carmine, Ferrara, Nicola, Girardi, Vincenzo, Grimaldi, Iolanda, Liguori, Ilaria, Pernas, Francesco Orfila, Paúl, Constança, Tramontano, Giovanni, and Tripodi, Francesca Saveria

Subjects
Male, Normative study, Aging, Neuropsychological Tests, 03 medical and health sciences, Cognition, 0302 clinical medicine, Linear regression, Humans, Cognitive Dysfunction, 030212 general & internal medicine, Cognitive impairment, Aged, Language, Aged, 80 and over, Word fluency, Geriatrics and Gerontology, Healthy subjects, Middle Aged, Mental Status and Dementia Tests, Confidence interval, Italy, Normative, Female, Psychology, 030217 neurology & neurosurgery, Clinical psychology
Abstract

OBJECTIVE: To devise an Italian version of the quick mild cognitive impairment screen (Qmci) and to obtain normative data. METHODS: An Italian version of the Qmci screen (Qmci-I) was administered to 307 subjects free from cognitive impairment. The normative sample was divided into three age levels (50-59; 60-69 and 70-80 years) and four education levels (3-5; 6-8; 9-13; >13 years of school attendance). Multiple regression analyses were used to evaluate the effect of age, sex and schooling on Qmci-I scores (overall and by domains) and to calculate cut-off values, with reference to the confidence interval on the fifth centile. RESULTS: The mean Qmci-I score was 64/100 (SD = 11). The age variable showed a significant negative effect on the overall Qmci-I score, with older people performing worse than younger ones. Conversely, education was associated with higher scores. Significant effects of age and education affected logical memory alone. For the other domains, the following effects were found: (1) higher age associated with lower scores on delayed recall; (2) higher education levels associated with higher scores on immediate recall, clock drawing and word fluency. The adjusted cut-off score for the Qmci-I screen in this sample was 49.4. Qmci-I scores were weakly correlated with those of MMSE (rho = 0.20). CONCLUSIONS: The Qmci-I is a rapid and multi-domain short cognitive screening instrument useful for evaluating cognitive functions. However, like other screening tools, it is significantly influenced by age and education, requiring normative data and correction of values when used in the clinical practice.

Published
2018

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