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202 results on '"Mazzarella, B."'

2. 12-MONTH OUTCOMES FROM A RANDOMIZED, DOUBLE-BLIND, SHAM CONTROLLED STUDY EVALUATING A NOVEL DRUG COATED BALLOON FOR THE TREATMENT OF BPH

Author

Elterman, D, primary, Kaplan, S, additional, Moss, J, additional, Freedman, S, additional, Coutinho, K, additional, Wu, N, additional, Efros, M, additional, D’Anna, R, additional, Padron, O, additional, Robertson, K, additional, Lawindy, S, additional, Mistry, S, additional, Shore, N, additional, Spier, J, additional, Kaminetsky, J, additional, Mazzarella, B, additional, Cahn, D, additional, Jalkut, M, additional, and Te, A, additional

Published
2023
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12. Experience with Isoflurane Anesthesia in Neurosurgery

Author

Mazzarella, B., Mastronardi, P., Tommasino, C., Gargiulo, G., Cafiero, T., Bergmann, H., editor, Brückner, J. B., editor, Gemperle, M., editor, Henschel, W. F., editor, Mayrhofer, O., editor, Meßmer, K., editor, Peter, K., editor, Lawin, Peter, editor, Van Aken, Hugo, editor, and Puchstein, Christoph, editor

Published
1986
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13. Isoflurane and Intracranial Pressure

Author

Mazzarella, B., Mastronardi, P., Cafiero, T., Gargiulo, G., Frangiosa, A., Tomassino, C., Stella, L., De Chiara, A., Miller, J. D., editor, Teasdale, G. M., editor, Rowan, J. O., editor, Galbraith, S. L., editor, and Mendelow, A. D., editor

Published
1986
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27. Treatment of symptomatic hyperLp(a)lipidemia with LDL-apheresis vs. usual care

Author

Stefanutti, C, Vivenzio, A., Di Giacomo, Salvatore, Mazzarella, B., Ferraro, Pietro Manuel, Abbolito, S., Ferraro, Pietro Manuel (ORCID:0000-0002-1379-022X), Stefanutti, C, Vivenzio, A., Di Giacomo, Salvatore, Mazzarella, B., Ferraro, Pietro Manuel, Abbolito, S., and Ferraro, Pietro Manuel (ORCID:0000-0002-1379-022X)

Abstract

Background/aims: To assess LDL-apheresis efficacy to lower Lp(a) and to compare the effects of Usual Medical Care (UMC) a 12-months study was carried out. The incidence of new coronary artery disease (CAD) events/need of revascularization, was also monitored. Methods: Twenty-one patients with hyperLp(a)lipidemia and angiographically documented CAD were randomly assigned to LDL-apheresis every week, or the UMC. Results: LDL-apheresis group, averaged an Lp(a) reduction of 57.8 ± 9.5% vs. basal values (P < 0.001). In the UMC group Lp(a) increased in 1 year to 14.7 ± 36.5% (P = 0.66). Stepwise multivariate regression analysis for predictors of Lp(a) including: type of treatment, smoking, hypertension, age, age at first cardiovascular event, initial Lp(a), LDL, and BMI values, was performed. Only the type of treatment was co-related (P < 0.001): Lp(a) variation (beta) = 0.863. The model has R2 adjusted relative risk of 0.725. Conclusion: LDL-apheresis could be the first line treatment of isolated hyperLp(a)lipidemia when CAD is established. New CAD events/cardiac interventions were not observed. © 2009 Elsevier Ltd. All rights reserved.

Published
2010

33. Effect of oral and transdermal hormone replacement therapy on lipid profile and Lp(a) level in menopausal women with hypercholesterolemia

Author

Perrone G, Stefanutti C, paola galoppi, Anelli G, Capri O, Lucani G, Vivenzio A, Mazzarella B, and Zichella L

Subjects
Estrogens, Conjugated (USP), Estradiol, Progesterone Congeners, hypercholesterolemia, hormone replacement therapy, lipid profile and lp (a) level in menopausal women with hypercholesterolemia, lipids, lp(a), oral and transdermal hormonal replacement therapy, Estrogen Replacement Therapy, Administration, Oral, Medroxyprogesterone Acetate, Administration, Cutaneous, Lipid Metabolism, Cohort Studies, Lipoproteins, LDL, Cholesterol, Humans, Drug Therapy, Combination, Female, Menopause, Lipoproteins, HDL, Triglycerides, Lipoprotein(a)
Abstract

The aim of this randomized clinical study was to evaluate the hormonal replacement therapy (HRT) effect on plasma lipoproteins and Lp(a) profile in 42 menopausal women with primary hypercholesterolemia (total cholesterol240 mg/dL).University clinic.42 hypercholesterolemic menopausal women were randomly assigned to the following groups; (1) transdermal estradiol, 50 micrograms + medroxyprogesterone 10 mg/day for days; (2) conjugated equine estrogens, 0.625 mg/day + medroxyprogesterone acetate 10 mg/day for 12 days; (3) no treatment. At baseline and after 3 and 6 months two blood samples were collected with a 24-hour interval in order to reduce intraindividual and laboratory variability. Serum total cholesterol, HDL cholesterol, triglycerides, LDL cholesterol, and Lp(a) were determined.Total cholesterol and LDL cholesterol significantly decreased after 6 months in both treated groups in comparison to untreated women; HDL cholesterol and triglycerides showed only minimal changes. HRT at the dosage utilized in the study did not seem influence the Lp(a) concentrations after 3 and 6 months.Both transdermal and oral estrogens at medium dosage have a favorable influence on total cholesterol and LDL-cholesterol level of hypercholesterolemic menopausal women, but Lp(a) remains resistant to manipulation.

Published
1996

42. Beta-endorphin concentrations both in plasma and in cerebrospinal fluid in response to acute painful stimuli

Author

Spaziante, Renato, Merola, B, Colao, A, Gargiulo, G, Cafiero, T, Irace, C, Rossi, E, Oliver, C, Lombardi, G, and Mazzarella, B.

Subjects
Adult, Male, Acute Disease, Osmolar Concentration, beta-Endorphin, Immunologic Techniques, Humans, Pain, Female
Abstract

The beta-endorphin-like-immunoreactivity (beta-ELI) has been evaluated both in plasma and in cerebrospinal fluid (CSF) in 30 patients during trans-sphenoidal surgery. Blood and liquoral samples were collected in five conditions: (1) "reference", (2) "pain", (3) "analgesia", (4) "end", and (5) "24th hour". A significant rise of both plasma and liquoral beta-ELI levels (p less than 0.00001 and p less than 0.08, respectively) when compared to basal ones occurred following the painful stimulation due to the divarication of the nasal mucosa by speculum. A significant decrease (p less than 0.01) was noticed for plasma concentrations at the third sample followed by a new significant increase at the end of the operation, (p less than 0.05 when compared to the third sample and p less than 0.01 when compared to the reference sample). In CSF, beta-ELI levels decreased at the third sample (p less than 0.01 when compared to the painful levels) and at the end of surgery (p less than 0.01, p less than 0.01 and p less than 0.05 vs first, second and third samples, respectively). Twenty-four hours after surgery either plasma and liquoral beta-ELI levels decreased (p less than 0.05). The modifications of the opiatergic system after acute painful stimuli should be, hence, characterized by an early rise followed by a progressive decrease of beta-ELI concentrations. The increase of plasma beta-ELI levels, at the end of surgery, could be due to pituitary manipulation with massive release in the peripheral blood.

Published
1990

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