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14 results on '"Maurel, Alice"'

1. Water Condensation Zones around Main Sequence Stars

Author

Turbet, Martin, Fauchez, Thomas J., Leconte, Jeremy, Bolmont, Emeline, Chaverot, Guillaume, Forget, Francois, Millour, Ehouarn, Selsis, Franck, Charnay, Benjamin, Ducrot, Elsa, Gillon, Michaël, Maurel, Alice, and Villanueva, Geronimo L.

Subjects
Astrophysics - Earth and Planetary Astrophysics, Physics - Atmospheric and Oceanic Physics, Physics - Geophysics
Abstract

Understanding the set of conditions that allow rocky planets to have liquid water on their surface -- in the form of lakes, seas or oceans -- is a major scientific step to determine the fraction of planets potentially suitable for the emergence and development of life as we know it on Earth. This effort is also necessary to define and refine the so-called "Habitable Zone" (HZ) in order to guide the search for exoplanets likely to harbor remotely detectable life forms. Until now, most numerical climate studies on this topic have focused on the conditions necessary to maintain oceans, but not to form them in the first place. Here we use the three-dimensional Generic Planetary Climate Model (PCM), historically known as the LMD Generic Global Climate Model (GCM), to simulate water-dominated planetary atmospheres around different types of Main-Sequence stars. The simulations are designed to reproduce the conditions of early ocean formation on rocky planets due to the condensation of the primordial water reservoir at the end of the magma ocean phase. We show that the incoming stellar radiation (ISR) required to form oceans by condensation is always drastically lower than that required to vaporize oceans. We introduce a Water Condensation Limit, which lies at significantly lower ISR than the inner edge of the HZ calculated with three-dimensional numerical climate simulations. This difference is due to a behavior change of water clouds, from low-altitude dayside convective clouds to high-altitude nightside stratospheric clouds. Finally, we calculated transit spectra, emission spectra and thermal phase curves of TRAPPIST-1b, c and d with H2O-rich atmospheres, and compared them to CO2 atmospheres and bare rock simulations. We show using these observables that JWST has the capability to probe steam atmospheres on low-mass planets, and could possibly test the existence of nightside water clouds., Comment: Accepted for publication in Astronomy & Astrophysics

Published
2023

3. Usability and acceptability of an automated respiratory rate counter to assess childhood pneumonia in Nepal

Author

Källander, Karin, Ward, Charlotte, Smith, Helen, Bhattarai, Radheshyam, KC, Ashish, Timsina, Deepak, Lamichhane, Bikash, Maurel, Alice, Ram Shrestha, Parashu, Baral, Sushil, McWhorter, Cindy, LaBarre, Paul, de Cola, Monica Anna, Baker, Kevin, Källander, Karin, Ward, Charlotte, Smith, Helen, Bhattarai, Radheshyam, KC, Ashish, Timsina, Deepak, Lamichhane, Bikash, Maurel, Alice, Ram Shrestha, Parashu, Baral, Sushil, McWhorter, Cindy, LaBarre, Paul, de Cola, Monica Anna, and Baker, Kevin

Abstract

AIM: Pneumonia is the leading cause of child death after the neonatal period, resulting from late care seeking and inappropriate treatment. Diagnosis involves counting respiratory rate (RR); however, RR counting remains challenging for health workers and miscounting, and misclassification of RR is common. We evaluated the usability of a new automated RR counter, the Philips Children's Respiratory Monitor (ChARM), to Female Community Health Volunteers (FCHVs), and its acceptability to FCHVs and caregivers in Nepal. METHODS: A cross-sectional study was conducted in Jumla district, Nepal. About 133 FCHVs were observed between September and December 2018 when using ChARM during 517 sick child consultations, 264 after training and 253 after 2 months of routine use of ChARM. Acceptability of the ChARM was explored using semi-structured interviews. RESULTS: FCHV adherence to guidelines after 2 months of using ChARM routinely was 52.8% (95% CI 46.6-58.9). The qualitative findings suggest that ChARM is acceptable to FCHVs and caregivers; however, capacity constraints such as older age and low literacy and impacted device usability were mentioned. CONCLUSION: Further research on the performance, cost-effectiveness and implementation feasibility of this device is recommended, especially among low-literate CHWs.

Published
2020
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4. Usability and acceptability of a multimodal respiratory rate and pulse oximeter device in case management of children with symptoms of pneumonia: A cross‐sectional study in Ethiopia

Author

Baker, Kevin, primary, Ward, Charlotte, additional, Maurel, Alice, additional, de Cola, Monica Anna, additional, Smith, Helen, additional, Getachew, Dawit, additional, Habte, Tedila, additional, McWhorter, Cindy, additional, LaBarre, Paul, additional, Karlstrom, Jonas, additional, Ameha, Agazi, additional, Tariku, Abraham, additional, Black, Jim, additional, Bassat, Quique, additional, and Källander, Karin, additional

Published
2020
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5. Automated Respiratory Rate Counter to Assess Children for Symptoms of Pneumonia: Protocol for Cross-Sectional Usability and Acceptability Studies in Ethiopia and Nepal

Author

Baker, Kevin, primary, Maurel, Alice, additional, Ward, Charlotte, additional, Getachew, Dawit, additional, Habte, Tedila, additional, McWhorter, Cindy, additional, LaBarre, Paul, additional, Karlström, Jonas, additional, Petzold, Max, additional, and Källander, Karin, additional

Published
2020
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6. Usability and acceptability of an automated respiratory rate counter to assess childhood pneumonia in Nepal

Author

Källander, Karin, primary, Ward, Charlotte, additional, Smith, Helen, additional, Bhattarai, Radheshyam, additional, KC, Ashish, additional, Timsina, Deepak, additional, Lamichhane, Bikash, additional, Maurel, Alice, additional, Ram Shrestha, Parashu, additional, Baral, Sushil, additional, McWhorter, Cindy, additional, LaBarre, Paul, additional, de Cola, Monica Anna, additional, and Baker, Kevin, additional

Published
2019
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7. Usability and acceptability of an automated respiratory rate counter to assess children for symptoms of pneumonia: A cross‐sectional study in Ethiopia

Author

Ward, Charlotte, primary, Baker, Kevin, additional, Smith, Helen, additional, Maurel, Alice, additional, Getachew, Dawit, additional, Habte, Tedila, additional, McWhorter, Cindy, additional, LaBarre, Paul, additional, Karlstrom, Jonas, additional, Black, Jim, additional, Bassat, Quique, additional, Ameha, Agazi, additional, Tariku, Abraham, additional, Petzold, Max, additional, and Källander, Karin, additional

Published
2019
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8. Expanding the Spectrum of BAF-Related Disorders : De Novo Variants in SMARCC2 Cause a Syndrome with Intellectual Disability and Developmental Delay

Author

Machol, Keren, Rousseau, Justine, Ehresmann, Sophie, Garcia, Thomas, Nguyen, Thi Tuyet Mai, Spillmann, Rebecca C., Sullivan, Jennifer A., Shashi, Vandana, Jiang, Yong hui, Stong, Nicholas, Fiala, Elise, Willing, Marcia, Pfundt, Rolph, Kleefstra, Tjitske, Cho, Megan T., McLaughlin, Heather, Rosello Piera, Monica, Orellana, Carmen, Martínez, Francisco, Caro-Llopis, Alfonso, Monfort, Sandra, Roscioli, Tony, Nixon, Cheng Yee, Buckley, Michael F., Turner, Anne, Jones, Wendy D., van Hasselt, Peter M., Hofstede, Floris C., van Gassen, Koen L.I., Brooks, Alice S., van Slegtenhorst, Marjon A., Lachlan, Katherine, Sebastian, Jessica, Madan-Khetarpal, Suneeta, Sonal, Desai, Sakkubai, Naidu, Thevenon, Julien, Faivre, Laurence, Maurel, Alice, Petrovski, Slavé, Krantz, Ian D., Tarpinian, Jennifer M., Rosenfeld, Jill A., Lee, Brendan H., Adams, David R., Alejandro, Mercedes E., Allard, Patrick, Azamian, Mahshid S., Bacino, Carlos A., Balasubramanyam, Ashok, and Undiagnosed Diseases Network

Subjects
developmental delay, dysmorphisms, speech delay, Bafopathy, intellectual disability, Genetics, Journal Article, Genetics(clinical), genotype-phenotype correlation, neurodevelopmental disorder, transcriptome
Abstract

SMARCC2 (BAF170) is one of the invariable core subunits of the ATP-dependent chromatin remodeling BAF (BRG1-associated factor) complex and plays a crucial role in embryogenesis and corticogenesis. Pathogenic variants in genes encoding other components of the BAF complex have been associated with intellectual disability syndromes. Despite its significant biological role, variants in SMARCC2 have not been directly associated with human disease previously. Using whole-exome sequencing and a web-based gene-matching program, we identified 15 individuals with variable degrees of neurodevelopmental delay and growth retardation harboring one of 13 heterozygous variants in SMARCC2, most of them novel and proven de novo. The clinical presentation overlaps with intellectual disability syndromes associated with other BAF subunits, such as Coffin-Siris and Nicolaides-Baraitser syndromes and includes prominent speech impairment, hypotonia, feeding difficulties, behavioral abnormalities, and dysmorphic features such as hypertrichosis, thick eyebrows, thin upper lip vermilion, and upturned nose. Nine out of the fifteen individuals harbor variants in the highly conserved SMARCC2 DNA-interacting domains (SANT and SWIRM) and present with a more severe phenotype. Two of these individuals present cardiac abnormalities. Transcriptomic analysis of fibroblasts from affected individuals highlights a group of differentially expressed genes with possible roles in regulation of neuronal development and function, namely H19, SCRG1, RELN, and CACNB4. Our findings suggest a novel SMARCC2-related syndrome that overlaps with neurodevelopmental disorders associated with variants in BAF-complex subunits.

Published
2019

9. Expanding the Spectrum of BAF-Related Disorders: De Novo Variants in SMARCC2 Cause a Syndrome with Intellectual Disability and Developmental Delay

Author

Cluster C, Child Health, Metabole ziekten patientenzorg, Integrale & Alg. Kindergen Patientenzorg, Genetica Sectie Genoomdiagnostiek, Machol, Keren, Rousseau, Justine, Ehresmann, Sophie, Garcia, Thomas, Nguyen, Thi Tuyet Mai, Spillmann, Rebecca C., Sullivan, Jennifer A., Shashi, Vandana, Jiang, Yong hui, Stong, Nicholas, Fiala, Elise, Willing, Marcia, Pfundt, Rolph, Kleefstra, Tjitske, Cho, Megan T., McLaughlin, Heather, Rosello Piera, Monica, Orellana, Carmen, Martínez, Francisco, Caro-Llopis, Alfonso, Monfort, Sandra, Roscioli, Tony, Nixon, Cheng Yee, Buckley, Michael F., Turner, Anne, Jones, Wendy D., van Hasselt, Peter M., Hofstede, Floris C., van Gassen, Koen L.I., Brooks, Alice S., van Slegtenhorst, Marjon A., Lachlan, Katherine, Sebastian, Jessica, Madan-Khetarpal, Suneeta, Sonal, Desai, Sakkubai, Naidu, Thevenon, Julien, Faivre, Laurence, Maurel, Alice, Petrovski, Slavé, Krantz, Ian D., Tarpinian, Jennifer M., Rosenfeld, Jill A., Lee, Brendan H., Adams, David R., Alejandro, Mercedes E., Allard, Patrick, Azamian, Mahshid S., Bacino, Carlos A., Balasubramanyam, Ashok, Undiagnosed Diseases Network, Cluster C, Child Health, Metabole ziekten patientenzorg, Integrale & Alg. Kindergen Patientenzorg, Genetica Sectie Genoomdiagnostiek, Machol, Keren, Rousseau, Justine, Ehresmann, Sophie, Garcia, Thomas, Nguyen, Thi Tuyet Mai, Spillmann, Rebecca C., Sullivan, Jennifer A., Shashi, Vandana, Jiang, Yong hui, Stong, Nicholas, Fiala, Elise, Willing, Marcia, Pfundt, Rolph, Kleefstra, Tjitske, Cho, Megan T., McLaughlin, Heather, Rosello Piera, Monica, Orellana, Carmen, Martínez, Francisco, Caro-Llopis, Alfonso, Monfort, Sandra, Roscioli, Tony, Nixon, Cheng Yee, Buckley, Michael F., Turner, Anne, Jones, Wendy D., van Hasselt, Peter M., Hofstede, Floris C., van Gassen, Koen L.I., Brooks, Alice S., van Slegtenhorst, Marjon A., Lachlan, Katherine, Sebastian, Jessica, Madan-Khetarpal, Suneeta, Sonal, Desai, Sakkubai, Naidu, Thevenon, Julien, Faivre, Laurence, Maurel, Alice, Petrovski, Slavé, Krantz, Ian D., Tarpinian, Jennifer M., Rosenfeld, Jill A., Lee, Brendan H., Adams, David R., Alejandro, Mercedes E., Allard, Patrick, Azamian, Mahshid S., Bacino, Carlos A., Balasubramanyam, Ashok, and Undiagnosed Diseases Network

Published
2019

10. Usability and acceptability of a multimodal respiratory rate and pulse oximeter device in case management of children with symptoms of pneumonia: A cross-sectional study in Ethiopia.

Author

Baker, Kevin, Ward, Charlotte, Maurel, Alice, de Cola, Monica Anna, Smith, Helen, Getachew, Dawit, Habte, Tedila, McWhorter, Cindy, LaBarre, Paul, Karlstrom, Jonas, Ameha, Agazi, Tariku, Abraham, Black, Jim, Bassat, Quique, and Källander, Karin

Subjects
SYMPTOMS, PULSE oximeters, COUGH, CROSS-sectional method, HEALTH facilities, PNEUMONIA, CHILD mortality, PNEUMONIA diagnosis, PNEUMONIA treatment, SOCIAL services case management, RESPIRATORY measurements, RESEARCH funding
Abstract

Aim: Pneumonia is the leading infectious cause of death among children under five globally. Many pneumonia deaths result from inappropriate treatment due to misdiagnosis of signs and symptoms. This study aims to identify whether health extension workers (HEWs) in Ethiopia, using an automated multimodal device (Masimo Rad-G), adhere to required guidelines while assessing and classifying under five children with cough or difficulty breathing and to understand device acceptability.Methods: A cross-sectional study was conducted in three districts of Southern Nations, Nationalities, and Peoples' Region, Ethiopia. Between September and December 2018, 133 HEWs were directly observed using Rad-G while conducting 599 sick child consultations. Usability was measured as adherence to the World Health Organization requirements to assess fast breathing and device manufacturer instructions for use. Acceptability was assessed using semi-structured interviews with HEWs, first-level health facility workers and caregivers.Results: Adherence using the Rad-G routinely for 2 months was 85.3% (95% CI 80.2, 89.3). Health workers and caregivers stated a preference for Rad-G. Users highlighted a number of device design issues.Conclusion: While demonstrating high levels of acceptability and usability, the device modifications to consider include better probe fit, improved user interface with exclusive age categories and simplified classification outcomes. [ABSTRACT FROM AUTHOR]

Published
2021
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11. Automated Respiratory Rate Counter to Assess Children for Symptoms of Pneumonia: Protocol for Cross-Sectional Usability and Acceptability Studies in Ethiopia and Nepal (Preprint)

Author

Baker, Kevin, primary, Maurel, Alice, additional, Ward, Charlotte, additional, Getachew, Dawit, additional, Habte, Tedila, additional, McWhorter, Cindy, additional, LaBarre, Paul, additional, Karlström, Jonas, additional, Petzold, Max, additional, and Källander, Karin, additional

Published
2019
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12. Expanding the Spectrum of BAF-Related Disorders: De Novo Variants in SMARCC2 Cause a Syndrome with Intellectual Disability and Developmental Delay

Author

Machol, Keren, primary, Rousseau, Justine, additional, Ehresmann, Sophie, additional, Garcia, Thomas, additional, Nguyen, Thi Tuyet Mai, additional, Spillmann, Rebecca C., additional, Sullivan, Jennifer A., additional, Shashi, Vandana, additional, Jiang, Yong-hui, additional, Stong, Nicholas, additional, Fiala, Elise, additional, Willing, Marcia, additional, Pfundt, Rolph, additional, Kleefstra, Tjitske, additional, Cho, Megan T., additional, McLaughlin, Heather, additional, Rosello Piera, Monica, additional, Orellana, Carmen, additional, Martínez, Francisco, additional, Caro-Llopis, Alfonso, additional, Monfort, Sandra, additional, Roscioli, Tony, additional, Nixon, Cheng Yee, additional, Buckley, Michael F., additional, Turner, Anne, additional, Jones, Wendy D., additional, van Hasselt, Peter M., additional, Hofstede, Floris C., additional, van Gassen, Koen L.I., additional, Brooks, Alice S., additional, van Slegtenhorst, Marjon A., additional, Lachlan, Katherine, additional, Sebastian, Jessica, additional, Madan-Khetarpal, Suneeta, additional, Sonal, Desai, additional, Sakkubai, Naidu, additional, Thevenon, Julien, additional, Faivre, Laurence, additional, Maurel, Alice, additional, Petrovski, Slavé, additional, Krantz, Ian D., additional, Tarpinian, Jennifer M., additional, Rosenfeld, Jill A., additional, Lee, Brendan H., additional, Campeau, Philippe M., additional, Adams, David R., additional, Alejandro, Mercedes E., additional, Allard, Patrick, additional, Azamian, Mahshid S., additional, Bacino, Carlos A., additional, Balasubramanyam, Ashok, additional, Barseghyan, Hayk, additional, Batzli, Gabriel F., additional, Beggs, Alan H., additional, Behnam, Babak, additional, Bican, Anna, additional, Bick, David P., additional, Birch, Camille L., additional, Bonner, Devon, additional, Boone, Braden E., additional, Bostwick, Bret L., additional, Briere, Lauren C., additional, Brown, Donna M., additional, Brush, Matthew, additional, Burke, Elizabeth A., additional, Burrage, Lindsay C., additional, Chen, Shan, additional, Clark, Gary D., additional, Coakley, Terra R., additional, Cogan, Joy D., additional, Cooper, Cynthia M., additional, Cope, Heidi, additional, Craigen, William J., additional, D’Souza, Precilla, additional, Davids, Mariska, additional, Dayal, Jyoti G., additional, Dell’Angelica, Esteban C., additional, Dhar, Shweta U., additional, Dillon, Ani, additional, Dipple, Katrina M., additional, Donnell-Fink, Laurel A., additional, Dorrani, Naghmeh, additional, Dorset, Daniel C., additional, Douine, Emilie D., additional, Draper, David D., additional, Eckstein, David J., additional, Emrick, Lisa T., additional, Eng, Christine M., additional, Eskin, Ascia, additional, Esteves, Cecilia, additional, Estwick, Tyra, additional, Ferreira, Carlos, additional, Fogel, Brent L., additional, Friedman, Noah D., additional, Gahl, William A., additional, Glanton, Emily, additional, Godfrey, Rena A., additional, Goldstein, David B., additional, Gould, Sarah E., additional, Gourdine, Jean-Philippe F., additional, Groden, Catherine A., additional, Gropman, Andrea L., additional, Haendel, Melissa, additional, Hamid, Rizwan, additional, Hanchard, Neil A., additional, Handley, Lori H., additional, Herzog, Matthew R., additional, Holm, Ingrid A., additional, Hom, Jason, additional, Howerton, Ellen M., additional, Huang, Yong, additional, Jacob, Howard J., additional, Jain, Mahim, additional, Johnston, Jean M., additional, Jones, Angela L., additional, Kohane, Isaac S., additional, Krasnewich, Donna M., additional, Krieg, Elizabeth L., additional, Krier, Joel B., additional, Lalani, Seema R., additional, Lau, C. Christopher, additional, Lazar, Jozef, additional, Lee, Hane, additional, Levy, Shawn E., additional, Lewis, Richard A., additional, Lincoln, Sharyn A., additional, Lipson, Allen, additional, Loo, Sandra K., additional, Loscalzo, Joseph, additional, Maas, Richard L., additional, Macnamara, Ellen F., additional, MacRae, Calum A., additional, Maduro, Valerie V., additional, Majcherska, Marta M., additional, Malicdan, May Christine V., additional, Mamounas, Laura A., additional, Manolio, Teri A., additional, Markello, Thomas C., additional, Marom, Ronit, additional, Martínez-Agosto, Julian A., additional, Marwaha, Shruti, additional, May, Thomas, additional, McConkie-Rosell, Allyn, additional, McCormack, Colleen E., additional, McCray, Alexa T., additional, Might, Matthew, additional, Moretti, Paolo M., additional, Morimoto, Marie, additional, Mulvihill, John J., additional, Murphy, Jennifer L., additional, Muzny, Donna M., additional, Nehrebecky, Michele E., additional, Nelson, Stan F., additional, Newberry, J. Scott, additional, Newman, John H., additional, Nicholas, Sarah K., additional, Novacic, Donna, additional, Orange, Jordan S., additional, Pallais, J. Carl, additional, Palmer, Christina G.S., additional, Papp, Jeanette C., additional, Parker, Neil H., additional, Pena, Loren D.M., additional, Phillips, John A., additional, Posey, Jennifer E., additional, Postlethwait, John H., additional, Potocki, Lorraine, additional, Pusey, Barbara N., additional, Reuter, Chloe M., additional, Robertson, Amy K., additional, Rodan, Lance H., additional, Sampson, Jacinda B., additional, Samson, Susan L., additional, Schoch, Kelly, additional, Schroeder, Molly C., additional, Scott, Daryl A., additional, Sharma, Prashant, additional, Signer, Rebecca, additional, Silverman, Edwin K., additional, Sinsheimer, Janet S., additional, Smith, Kevin S., additional, Splinter, Kimberly, additional, Stoler, Joan M., additional, Sweetser, David A., additional, Tifft, Cynthia J., additional, Toro, Camilo, additional, Tran, Alyssa A., additional, Urv, Tiina K., additional, Valivullah, Zaheer M., additional, Vilain, Eric, additional, Vogel, Tiphanie P., additional, Wahl, Colleen E., additional, Walley, Nicole M., additional, Walsh, Chris A., additional, Ward, Patricia A., additional, Waters, Katrina M., additional, Westerfield, Monte, additional, Wise, Anastasia L., additional, Wolfe, Lynne A., additional, Worthey, Elizabeth A., additional, Yamamoto, Shinya, additional, Yang, Yaping, additional, Yu, Guoyun, additional, Zastrow, Diane B., additional, and Zheng, Allison, additional

Published
2019
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13. Usability and acceptability of an automated respiratory rate counter to assess children for symptoms of pneumonia: A cross-sectional study in Ethiopia.

Author

Ward, Charlotte, Baker, Kevin, Smith, Helen, Maurel, Alice, Getachew, Dawit, Habte, Tedila, McWhorter, Cindy, LaBarre, Paul, Karlstrom, Jonas, Black, Jim, Bassat, Quique, Ameha, Agazi, Tariku, Abraham, Petzold, Max, and Källander, Karin

Subjects
CROSS-sectional method, PNEUMONIA, HEALTH facilities, SEMI-structured interviews, PUBLIC health, PNEUMONIA diagnosis, PNEUMONIA treatment, RESPIRATORY measurements, RESEARCH funding
Abstract

Aim: Manually counting respiratory rate (RR) is commonly practiced by community health workers to detect fast breathing, an important sign of childhood pneumonia. Correctly counting and classifying breaths manually is challenging, often leading to inappropriate treatment. This study aimed to determine the usability of a new automated RR counter (ChARM) by health extension workers (HEWs), and its acceptability to HEWs, first-level health facility workers (FLHFWs) and caregivers in Ethiopia.Methods: A cross-sectional study was conducted in one region of Ethiopia between May and August 2018. A total of 131 HEWs were directly observed conducting 262 sick child consultations after training and 337 after 2 months. Usability was measured as adherence to the WHO requirements to assess fast breathing and device manufacturer instructions for use (IFU). Acceptability was measured through semi-structured interviews.Results: After 2 months, HEWs were shown to adhere to the requirements in 74.6% consultations; an increase of 18.6% after training (P < .001). ChARM is acceptable to users and caregivers, with HEWs suggesting that ChARM increased client flow and stating a willingness to use ChARM in future.Conclusion: Further research on the performance, cost-effectiveness and implementation of this device is warranted to inform policy decisions in countries with a high childhood pneumonia burden. [ABSTRACT FROM AUTHOR]

Published
2020
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14. Usability and acceptability of an automated respiratory rate counter to assess childhood pneumonia in Nepal.

Author

Källander K, Ward C, Smith H, Bhattarai R, Kc A, Timsina D, Lamichhane B, Maurel A, Ram Shrestha P, Baral S, McWhorter C, LaBarre P, de Cola MA, and Baker K

Subjects
Aged, Child, Community Health Workers, Cross-Sectional Studies, Female, Humans, Infant, Newborn, Nepal, Pneumonia diagnosis, Respiratory Rate
Abstract

Aim: Pneumonia is the leading cause of child death after the neonatal period, resulting from late care seeking and inappropriate treatment. Diagnosis involves counting respiratory rate (RR); however, RR counting remains challenging for health workers and miscounting, and misclassification of RR is common. We evaluated the usability of a new automated RR counter, the Philips Children's Respiratory Monitor (ChARM), to Female Community Health Volunteers (FCHVs), and its acceptability to FCHVs and caregivers in Nepal., Methods: A cross-sectional study was conducted in Jumla district, Nepal. About 133 FCHVs were observed between September and December 2018 when using ChARM during 517 sick child consultations, 264 after training and 253 after 2 months of routine use of ChARM. Acceptability of the ChARM was explored using semi-structured interviews., Results: FCHV adherence to guidelines after 2 months of using ChARM routinely was 52.8% (95% CI 46.6-58.9). The qualitative findings suggest that ChARM is acceptable to FCHVs and caregivers; however, capacity constraints such as older age and low literacy and impacted device usability were mentioned., Conclusion: Further research on the performance, cost-effectiveness and implementation feasibility of this device is recommended, especially among low-literate CHWs., (© 2019 Malaria Consortium. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.)

Published
2020
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