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2. Short physical performance battery is not associated with falls and injurious falls in older persons: longitudinal data of the SCOPE project

Author

Freiberger, Ellen, Fabbietti, Paolo, Corsonello, Andrea, Lattanzio, Fabrizia, Sieber, Cornel, Tap, Lisanne, Mattace-Raso, Francesco, Ärnlöv, Johan, Carlsson, Axel C., Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Moreno-Gonzalez, Rafael, Formiga, Francesc, Martinez, Sara Lainez, Gil, Pedro, Kostka, Tomasz, Guligowska, Agnieszka, Yehoshua, Ilan, Melzer, Itshak, and Kob, Robert

Published
2024
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4. Diabetes and factors associated with cognitive and functional decline. The screening for CKD among older people across Europe (SCOPE) study

Author

Formiga, Francesc, Badía-Tejero, Ana María, Corsonello, Andrea, Ärnlöv, Johan, Carlsson, Axel C., Mattace-Raso, Francesco, Tap, Lisanne, Kostka, Tomasz, Guligowska, Agnieszka, Sieber, Cornel. C., Kob, Robert, Ben-Romano, Ronit, Yehoshua, Ilan, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard H., Fabbietti, Paolo, Lattanzio, Fabrizia, and Moreno-González, Rafael

Published
2023
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6. Limited predictive value of bioelectrical phase angle for the development of sarcopenia in older Europeans

Author

Pigłowska, Małgorzata, Corsonello, Andrea, Kostka, Tomasz, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Ärnlöv, Johan, Carlsson, Axel C., Tap, Lisanne, Mattace-Raso, Francesco, Formiga, Francesc, Moreno-González, Rafael, Kob, Robert, Sieber, Cornel, Gil, Pedro, Martinez, Sara Lainez, Ben-Romano, Ronit, Melzer, Itshak, Fabbietti, Paolo, Lattanzio, Fabrizia, and Guligowska, Agnieszka

Published
2024
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7. Efficacy of erythropoietin as a neuroprotective agent in CKD-associated cognitive dysfunction: A literature systematic review

Author

Barbieri, Michelangela, Chiodini, Paolo, Di Gennaro, Piergiacomo, Hafez, Gaye, Liabeuf, Sophie, Malyszko, Jolanta, Mani, Laila-Yasmin, Mattace-Raso, Francesco, Pepin, Marion, Perico, Norberto, Simeoni, Mariadelina, Zoccali, Carmine, Tortorella, Giovanni, Capuano, Annalisa, Remuzzi, Giuseppe, Capasso, Giovambattista, and Paolisso, Giuseppe

Published
2024
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8. Kidney function and other associated factors of sarcopenia in community-dwelling older adults: The SCOPE study

Author

Moreno-González, Rafael, Cruzado, Josep Maria, Corsonello, Andrea, Fabbietti, Paolo, Tap, Lisanne, Mattace-Raso, Francesco, Ärnlöv, Johan, Carlsson, Axel C., Guligowska, Agnieszka, Kostka, Tomasz, Artzi-Medvedik, Rada, Melzer, Itshak, Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Kob, Robert, Sieber, Cornel, Lattanzio, Fabrizia, and Formiga, Francesc

Published
2024
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10. Atypical presentation of COVID-19 in older patients is associated with frailty but not with adverse outcomes

Author

van Son, Joy E., Kahn, Elisabeth C. P., van der Bol, Jessica M., Barten, Dennis G., Blomaard, Laura C., van Dam, Carmen, Ellerbroek, Jacobien, Jansen, Steffy W. M., Lekx, Anita, van der Linden, Carolien M. J., Looman, Roy, Maas, Huub A. A. M., Mattace-Raso, Francesco U. S., Mooijaart, Simon P., van Munster, Barbara C., Peters, Annefleur, Polinder-Bos, Harmke A., Smits, Rosalinde A. L., Spies, Petra E., Wassenburg, Anna, Wassenburg, Nora, Willems, Hanna C., Schouten, Henrike J., and Robben, Sarah H. M.

Published
2023
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18. Clusters of risk factors in metabolic syndrome and their influence on central blood pressure in a global study

Author

Laucyte-Cibulskiene, Agne, Chen, Chen-Huan, Cockroft, John, Cunha, Pedro G., Kavousi, Maryam, Laucevicius, Aleksandras, Muiesan, Maria Lorenza, Rietzschel, Ernst R., Ryliskyte, Ligita, Strazhesko, Irina D., Vlachopoulos, Charalambos, Cotter, Jorge, Dudinskaya, Ekatherina N., Gale, Nichola, Ahmadizar, Fariba, Mattace-Raso, Francesco U. S., Munnery, Maggie, Oliveira, Pedro, Paini, Anna, Salvetti, Massimo, Tkacheva, Olga N., Lakatta, Edward G., Nilsson, Peter M., and Scuteri, Angelo

Published
2022
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20. Diabetes, sarcopenia and chronic kidney disease; the Screening for CKD among Older People across Europe (SCOPE) study

Author

Formiga, Francesc, Moreno-González, Rafael, Corsonello, Andrea, Carlsson, Axel, Ärnlöv, Johan, Mattace-Raso, Francesco, Kostka, Tomasz, Weingart, Christian, Roller-Wirnsberger, Regina, Tap, Lisanne, Guligowska, Agnieszka, Sieber, Cornel, Wirnsberger, Gerhard, Artzi-Medvedik, Rada, Yehoshua, Ilan, Giuli, Cinzia, Lattanzio, Fabrizia, and Corbella, Xavier

Published
2022
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22. Impact of Serum Phosphate on Hemoglobin Level: A Longitudinal Analysis on a Large Cohort of Dialysis Patients.

Author

Calabrese, Vincenzo, Tripepi, Giovanni Luigi, Santoro, Domenico, Cernaro, Valeria, Panuccio, Vincenzo Antonio, Mezzatesta, Sabrina, Mattace-Raso, Francesco, and Torino, Claudia

Subjects
FIBROBLAST growth factors, MEDIAN (Mathematics), BLOOD serum analysis, KIDNEY physiology, HEMODIALYSIS patients
Abstract

Background/Objectives: Phosphate is a macro-element involved in all cellular energetic processes. As about 90% of the phosphate filtered by the glomerulus is excreted by kidneys, the impairment of renal function and the consequent over-secretion of parathyroid hormone and fibroblast growth factor 23 results in the increase in the serum phosphate levels. The association between phosphate and hemoglobin is controversial, as both direct and indirect relationships have been reported. The present study aims to investigate the relationship between phosphate and hemoglobin in a large prospective, longitudinal cohort including dialysis patients from the Sicilian Registry of Nephrology, Dialysis, and Transplantation. Methods: In this prospective cohort study, we included 6263 hemodialysis patients to achieve a total of 120,462 repeated measurements of serum phosphate and hemoglobin over time. The longitudinal association between phosphate and hemoglobin was analyzed by univariate and multivariate Linear Mixed Models. Results: The mean age was 66 ± 16 years and the median dialysis vintage was 5 months [IQR: 2–16]. Mean and median values of hemoglobin and phosphate were 10.7 g/dL (SD 1.3 g/dL) and 4.6 mg/dL [IQR 3.9–5.5 mg/dL], respectively. The multivariate model, adjusted for potential confounders, confirmed the positive association between serum phosphate and hemoglobin [adjβ = 0.13, 95%CI 0.03–0.23, p = 0.01)]. These results were confirmed in analyses stratified for the use of phosphate binders. Conclusions: In our large cohort of dialysis patients, we found a linear, direct relationship between phosphate and hemoglobin levels. As a reduction in phosphate is associated with a parallel reduction in hemoglobin levels, hypophosphatemia can accentuate anemia in dialysis patients. Our results generate the hypothesis that monitoring serum phosphate in clinical practice might provide a better management of anemia. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Deterioration of Kidney Function Is Affected by Central Arterial Stiffness in Late Life

Author

Tap, Lisanne, Borsboom, Kim, Corsonello, Andrea, Lattanzio, Fabrizia, Mattace-Raso, Francesco, Tap, Lisanne, Borsboom, Kim, Corsonello, Andrea, Lattanzio, Fabrizia, and Mattace-Raso, Francesco

Abstract

Cardiovascular diseases affect kidney function. The aim of this study was to investigate the possible associations between hemodynamic parameters and change in kidney function in individuals aged 75 years and older. Data on hemodynamics and blood and urine samples were collected at baseline and during one-year visits. Hemodynamics were split into two groups based on median values. Changes in the estimated glomerular filtration rate (eGFR) were investigated between low and high groups for each hemodynamic parameter using analysis of variance. Changes in the albumin–creatinine ratio (ACR) were examined as binary outcomes (large increase vs. stable) using logistic regression. The population consisted of 252 participants. Participants in the high central systolic blood pressure (cSBP) group had a greater decline in eGFR than participants in the low cSBP group (−6.3% vs. −2.7%, p = 0.006). Participants in the high aortic pulse wave velocity (aPWV) group had a greater decline in eGFR than those in the low aPWV group (−6.8% vs. −2.5%, p = 0.001). Other hemodynamic parameters were not associated with eGFR changes. Hemodynamics were not associated with changes in the ACR; aPWV and cSBP appear to be predictors for eGFR decline in older age; monitoring and treatment of elevated stiffness might be helpful in order to prevent kidney function decline.

Published
2024

28. Short physical performance battery is not associated with falls and injurious falls in older persons:longitudinal data of the SCOPE project

Author

Freiberger, Ellen, Fabbietti, Paolo, Corsonello, Andrea, Lattanzio, Fabrizia, Sieber, Cornel, Tap, Lisanne, Mattace-Raso, Francesco, Ärnlöv, Johan, Carlsson, Axel C., Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Moreno-Gonzalez, Rafael, Formiga, Francesc, Martinez, Sara Lainez, Gil, Pedro, Kostka, Tomasz, Guligowska, Agnieszka, Yehoshua, Ilan, Melzer, Itshak, Kob, Robert, Freiberger, Ellen, Fabbietti, Paolo, Corsonello, Andrea, Lattanzio, Fabrizia, Sieber, Cornel, Tap, Lisanne, Mattace-Raso, Francesco, Ärnlöv, Johan, Carlsson, Axel C., Roller-Wirnsberger, Regina, Wirnsberger, Gerhard, Moreno-Gonzalez, Rafael, Formiga, Francesc, Martinez, Sara Lainez, Gil, Pedro, Kostka, Tomasz, Guligowska, Agnieszka, Yehoshua, Ilan, Melzer, Itshak, and Kob, Robert

Abstract

Introduction: Falls and fall-related injuries in older persons are a major public health problem. Our objective was to study the predictive value of the Short Physical Performance Battery (SPPB) in the cohort of the SCOPE project on falls, injurious falls, and possible difference of prediction between indoors and outdoors falls. Methods: For this sub-study of the SCOPE project participants reporting no falls at baseline, and survey data on falls at the 12-month and 24-month follow-up were included. Participant´s characteristics were assessed during the baseline interview and medical examinations. Falls as well as injurious falls and fall circumstances were obtained self-reported. SPPB and its association with fallers vs. no fallers at 12 and at 24 months were studied with logistic regression models. Results: The 1198 participants had a median age of 79 years (77–82), and a median SPPB of 10 (8–11), with a 52.5% of female. A total of 227 and 277 falls (12- and 24- month visits, respectively) were reported. In the crude model, the SPPB sum scores (p < 0.001) as well as most single item scores were significant different between fallers and non-fallers over time. However, the association was attenuated in models adjusted for age, sex, marital status, number of medications, quality of life, handgrip strength, and muscle mass [e.g., 12 months; OR 0.94 (0.87–1.02)]. While SPPB fails to differentiate between injurious and non-injurious falls (p = 0.48), a lower SPPB score was associated with falls at home (p < 0.01) after 24 months.Conclusion: SBPP was not able to significantly predict the risk of falling as well as experiencing an injurious fall. Trial registration: This study was registered prospectively on 25th February 2016 at clinicaltrials.gov (NCT02691546).

Published
2024

31. Animal models to study cognitive impairment of chronic kidney disease.

Author

Silva, Pedro H. Imenez, Pepin, Marion, Figurek, Andreja, Gutiérrez-Jiménez, Eugenio, Bobot, Mickaël, Iervolino, Anna, Mattace-Raso, Francesco, Hoorn, Ewout J., Bailey, Matthew A., Hénaut, Lucie, Nielsen, Rikke, Frische, Sebastian, Trepiccione, Francesco, Hafez, Gaye, Altunkaynak, Hande O., Endlich, Nicole, Unwin, Robert, Capasso, Giovambattista, Pesic, Vesna, and Massy, Ziad

Subjects
CHRONIC kidney failure, COGNITION disorders, EXECUTIVE function, ACTIVITIES of daily living, COGNITION
Abstract

Mild cognitive impairment (MCI) is common in people with chronic kidney disease (CKD), and its prevalence increases with progressive loss of kidney function. MCI is characterized by a decline in cognitive performance greater than expected for an individual age and education level but with minimal impairment of instrumental activities of daily living. Deterioration can affect one or several cognitive domains (attention, memory, executive functions, language, and perceptual motor or social cognition). Given the increasing prevalence of kidney disease, more and more people with CKD will also develop MCI causing an enormous disease burden for these individuals, their relatives, and society. However, the underlying pathomechanisms are poorly understood, and current therapies mostly aim at supporting patients in their daily lives. This illustrates the urgent need to elucidate the pathogenesis and potential therapeutic targets and test novel therapies in appropriate preclinical models. Here, we will outline the necessary criteria for experimental modeling of cognitive disorders in CKD. We discuss the use of mice, rats, and zebrafish as model systems and present valuable techniques through which kidney function and cognitive impairment can be assessed in this setting. Our objective is to enable researchers to overcome hurdles and accelerate preclinical research aimed at improving the therapy of people with CKD and MCI. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Pathways Towards Lean TAVR

Author

Van Wiechen, Maarten P., Ooms, Joris F., Hokken, Thijmen W., De Ronde-Tillmans, Marjo J., Goudzwaard, Jeannette A., Daemen, Joost, De Jaegere, Peter P., Mattace-Raso, Francesco U., and Van Mieghem, Nicolas M.

Published
2020
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42. Animal models to study cognitive impairment of chronic kidney disease

Author

Imenez Silva, Pedro H., Pepin, Marion, Figurek, Andreja, Gutiérrez-Jiménez, Eugenio, Bobot, Mickaël, Iervolino, Anna, Mattace-Raso, Francesco, Hoorn, Ewout J., Bailey, Matthew A., Hénaut, Lucie, Nielsen, Rikke, Frische, Sebastian, Trepiccione, Francesco, Hafez, Gaye, Altunkaynak, Hande O., Endlich, Nicole, Unwin, Robert, Capasso, Giovambattista, Pesic, Vesna, Massy, Ziad, and Wagner, Carsten A.

Published
2024
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43. The effectiveness of a coordinated preventive care approach for healthy ageing (UHCE) among older persons in five European cities: A pre-post controlled trial

Author

Franse, Carmen B., van Grieken, Amy, Alhambra-Borrás, Tamara, Valía-Cotanda, Elisa, van Staveren, Rob, Rentoumis, Tasos, Markaki, Athina, Bilajac, Lovorka, Marchesi, Vanja Vasiljev, Rukavina, Tomislav, Verma, Arpana, Williams, Greg, Koppelaar, Elin, Martijn, Rens, Voorham, Antonius J.J., Mattace Raso, Francesco, Garcés-Ferrer, Jorge, and Raat, Hein

Published
2018
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44. Prevalence of Sarcopenia in Chronic Heart Failure and Modulating Role of Chronic Kidney Disease.

Author

Formiga, Francesc, Moreno-Gónzalez, Rafael, Corsonello, Andrea, Mattace-Raso, Francesco, Carlsson, Axel C., Ärnlöv, Johan, Kostka, Joanna, Freiberger, Ellen, Roller-Wirnsberger, Regina, Tap, Lisanne, Sołtysik, Bartłomiej K., Artzi-Medvedik, Rada, Kob, Robert, Yehoshua, Ilan, Wirnsberger, Gerhard H., Fabbietti, Paolo, Lattanzio, Fabrizia, and Chivite, David

Subjects
CHRONIC kidney failure, SARCOPENIA, HEART failure, OLDER people, VENTRICULAR ejection fraction
Abstract

Introduction: Sarcopenia, heart failure (HF), and chronic kidney disease (CKD) are common among the older people. Our objective was to evaluate the frequency of sarcopenia, among community-dwelling older adults with HF, possible causative factors, and the additive factor of CKD. Methods: A cross-sectional analysis of 1,420 older people living in the community was carried out. Participants (aged 75 years and more) came from a European multicenter prospective cohort (SCOPE study). Global geriatric assessment including short physical performance battery, handgrip strength test, and bioelectrical impedance analysis was performed. Previous known HF was defined as physician-diagnosed HF registered in the patient's medical record or the use of HF-related medications, regardless of left ventricular ejection fraction (LVEF). Sarcopenia was defined by the updated criteria of the European Working Group on Sarcopenia in Older People (EWGSOP2). Estimated glomerular filtration rate was calculated using Berlin Initiative Study (BIS) to define the stages of CKD. Two-year mortality was also collected. Results: A total of 226 (15.9%) participants had a prior chronic HF diagnosis, with a median age of 80.0 (5.0), and 123 (54.4%) were women. Using EWGSOP2 definition, 11.5% HF and 10.7% in non-HF participants met diagnostic criteria for sarcopenia. In multivariate analyses, only a lower body mass index (BMI) (odds ratios [OR], 0.82; 95% confidence interval [CI], 0.73–0.93) and lower short physical performance battery score (OR, 0.81; 95% CI, 0.69–0.96) were associated with sarcopenia. Patients with HF and sarcopenia have a similar all-cause mortality risk but higher 2-year cardiovascular mortality risk (p = 0.047). Discussion/Conclusion: One out of ten community-dwelling older adults with concurrent clinical stable chronic HF, without considering LVEF, have sarcopenia. Lower BMI and poor physical performance are associated with sarcopenia in this population, but not CKD. [ABSTRACT FROM AUTHOR]

Published
2024
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46. Delirium in older patients with COVID‐19: Prevalence, risk factors and clinical outcomes across the first three waves of the pandemic

Author

Minnema, Julia, primary, Tap, Lisanne, additional, van der Bol, Jessica M., additional, van Deudekom, Floor J. A., additional, Faes, Miriam C., additional, Jansen, Steffy W. M., additional, van der Linden, Carolien M. J., additional, Lucke, Jacinta A., additional, Mooijaart, Simon P., additional, van Munster, Barbara, additional, Noordam, Raymond, additional, van Raaij, Bas F. M., additional, Ruiter, Rikje, additional, Smits, Rosalinde A. L., additional, Willems, Hanna C., additional, Mattace‐Raso, Francesco U. S., additional, and Polinder‐Bos, Harmke A., additional

Published
2023
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47. Effects of the DICE Method to Improve Timely Recognition and Treatment of Neuropsychiatric Symptoms in Early Alzheimer’s Disease at the Memory Clinic: The BEAT-IT Study

Author

Eikelboom, Willem S., van den Berg, Esther, Coesmans, Michiel, Goudzwaard, Jeannette A., Koopmanschap, Marc, Lazaar, Najoua, van Bruchem-Visser, Rozemarijn L., Driesen, Jan J. M., den Heijer, Tom, Hoogers, Susanne, de Jong, Frank Jan, Mattace-Raso, Francesco, Thomeer, Elsbeth C., Vrenken, Suzanne, Vroegindeweij, Lilian J. H. M., Zuidema, Sytse U., Singleton, Ellen H., van Swieten, John C., Ossenkoppele, Rik, and Papma, Janne M.

Subjects
Psychiatry and Mental health, Clinical Psychology, General Neuroscience, General Medicine, Geriatrics and Gerontology
Abstract

Background: Neuropsychiatric symptoms (NPS) are highly prevalent in Alzheimer’s disease (AD) and are associated with negative outcomes. However, NPS are currently underrecognized at the memory clinic and non-pharmacological interventions are scarcely implemented. Objective: To evaluate the effectiveness of the Describe, Investigate, Create, Evaluate (DICE) method™ to improve the care for NPS in AD at the memory clinic. Methods: We enrolled sixty community-dwelling people with mild cognitive impairment or AD dementia and NPS across six Dutch memory clinics with their caregivers. The first wave underwent care as usual (n = 36) and the second wave underwent the DICE method (n = 24). Outcomes were quality of life (QoL), caregiver burden, NPS severity, NPS-related distress, competence managing NPS, and psychotropic drug use. Reliable change index was calculated to identify responders to the intervention. A cost-effectiveness analysis was performed and semi-structured interviews with a subsample of the intervention group (n = 12). Results: The DICE method did not improve any outcomes over time compared to care as usual. Half of the participants of the intervention group (52%) were identified as responders and showed more NPS and NPS-related distress at baseline compared to non-responders. Interviews revealed substantial heterogeneity among participants regarding NPS-related distress, caregiver burden, and availability of social support. The intervention did not lead to significant gains in quality-adjusted life years and well-being years nor clear savings in health care and societal costs. Conclusion: The DICE method showed no benefits at group-level, but individuals with high levels of NPS and NPS-related distress may benefit from this intervention.

Published
2023

48. Estimated glomerular filtration rate and functional status among older people: A systematic review

Author

Corsonello, Andrea, Roller-Wirnsberger, Regina, Di Rosa, Mirko, Fabbietti, Paolo, Wirnsberger, Gerhard, Kostka, Tomasz, Guligowska, Agnieszka, Tap, Lisanne, Mattace-Raso, Francesco, Gil, Pedro, Guardado-Fuentes, Lara, Meltzer, Itshak, Yehoshua, Ilan, Artzi-Medevdik, Rada, Formiga, Francesc, Moreno-González, Rafael, Weingart, Christian, Freiberger, Ellen, Ärnlöv, Johan, Carlsson, Axel C., and Lattanzio, Fabrizia

Published
2018
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49. LRP10 genetic variants in familial Parkinson's disease and dementia with Lewy bodies: a genome-wide linkage and sequencing study

Author

Bonifati, Vincenzo, Quadri, Marialuisa, Mandemakers, Wim, Kievit, Anneke J.A., Boon, Agnita J.W., Rood, Janneke P.A, Vergouw, Leonie J.M., de Jong, Frank J., van Swieten, John C., Mattace-Raso, Francesco U.S., Leenders, Klaus L., Ferreira, Joaquim J., Correia Guedes, Leonor, Puschmann, Andreas, Ygland, Emil, Nilsson, Christer, Chien, Hsin F., Barbosa, Egberto, Bannach Jardim, Laura, Rieder, Carlos R.M., Chang, Hsiu-Chen, Lu, Chin-Song, Wu-Chou, Yah-Huei, Yeh, Tu-Hsueh, Lopiano, Leonardo, Tassorelli, Cristina, Pacchetti, Claudio, Riboldazzi, Giulio, Bono, Giorgio, Comi, Cristoforo, Padovani, Alessandro, Borroni, Barbara, Raudino, Francesco, Fincati, Emiliana, Tinazzi, Michele, Bonizzato, Alberto, Ferracci, Carlo, Dalla Libera, Alessio, Abbruzzese, Giovanni, Cortelli, Pietro, Capellari, Sabina, Marconi, Roberto, Guidi, Marco, Onofrj, Marco, Thomas, Astrid, Vanacore, Nicola, Meco, Giuseppe, Fabrizio, Edito, Fabbrini, Giovanni, Berardelli, Alfredo, Stocchi, Fabrizio, Vacca, Laura, Barone, Paolo, Picillo, Marina, De Michele, Giuseppe, Criscuolo, Chiara, De Mari, Michele, Dell'Aquila, Claudia, Iliceto, Gianni, Toni, Vincenzo, Trianni, Giorgio, Gagliardi, Monica, Annesi, Grazia, Quattrone, Aldo, Saddi, Valeria, Cossu, Gianni, Melis, Maurizio, Grochowska, Martyna M, Masius, Roy, Geut, Hanneke, Breedveld, Guido J, Kuipers, Demy, Minneboo, Michelle, Vergouw, Leonie J M, Carreras Mascaro, Ana, Yonova-Doing, Ekaterina, Simons, Erik, Zhao, Tianna, Di Fonzo, Alessio B, Parchi, Piero, Melis, Marta, Brouwer, Rutger W W, Heijsman, Daphne, Ingrassia, Angela M T, Calandra Buonaura, Giovanna, Rood, Janneke P, Rozemuller, Annemieke J, Sarchioto, Marianna, Fen Chien, Hsin, Olgiati, Simone, Boon, Agnita J W, Hoogers, Susanne E, Ghazvini, Mehrnaz, IJpma, Arne S, van IJcken, Wilfred F J, Nicholl, David J, Kievit, Anneke J, Majoor-Krakauer, Danielle, van Swieten, John C, de Jong, Frank J, Ferreira, Joaquim J, Cossu, Giovanni, and van de Berg, Wilma D J

Published
2018
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50. Association of Antidementia Drugs and Mortality in Community-Dwelling Frail Older Patients With Dementia: The Role of Mortality Risk Assessment

Author

Cruz-Jentoft, Alfonso, Durando, Mario, Ferrucci, Luigi, Fratiglioni, Laura, Mattace-Raso, Francesco, Paccalin, Marc, Ruppe, Georg, Schulz, Ralf-Joachim, Topinkova, Eva, Trifirò, Gianluca, Welmer, Anna-Karin, Pilotto, Alberto, Polidori, Maria Cristina, Veronese, Nicola, Panza, Francesco, Arboretti Giancristofaro, Rosa, Pilotto, Andrea, Daragjati, Julia, Carrozzo, Eleonora, Prete, Camilla, Gallina, Pietro, Padovani, Alessandro, and Maggi, Stefania

Published
2018
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