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1. Controlling the color appearance of objects by optimizing the illumination spectrum

Author

Yamaguchi, Mariko, Tsuchida, Masaru, Matsumoto, Takahiro, Tokunaga, Tetsuro, and Mochizuki, Takayoshi

Subjects
Computer Science - Computer Vision and Pattern Recognition, Computer Science - Graphics, J.5
Abstract

We have developed an innovative lighting system that changes specific target colors while keeping the lights appearing naturally white. By precisely controlling the spectral power distribution (SPD) of illumination and harnessing the unique phenomenon of metamerism, our system achieves unique color variations in ways you've never seen before. Our system calculates the optimal SPDs of illumination for given materials to intensively induce metamerism, and then synthesizes the illumination using various colors of LEDs. We successfully demonstrated the system's implementation at Paris Fashion Week 2024. As models step onto the stage, their dresses initiate a captivating transformation. Our system altering the colors of the dresses, showcasing an impressive transition from one stunning color to another.

Published
2024
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9. Catalog of Gamma-ray Glows during Four Winter Seasons in Japan

Author

Wada, Yuuki, Matsumoto, Takahiro, Enoto, Teruaki, Nakazawa, Kazuhiro, Yuasa, Takayuki, Furuta, Yoshihiro, Yonetoku, Daisuke, Sawano, Tatsuya, Okada, Go, Nanto, Hidehito, Hisadomi, Shohei, Tsuji, Yuna, Diniz, Gabriel Sousa, Makishima, Kazuo, and Tsuchiya, Harufumi

Subjects
Physics - Atmospheric and Oceanic Physics, Astrophysics - High Energy Astrophysical Phenomena
Abstract

In 2015 the Gamma-Ray Observation of Winter Thunderstorms (GROWTH) collaboration launched a mapping observation campaign for high-energy atmospheric phenomena related to thunderstorms and lightning discharges. This campaign has developed a detection network of gamma rays with up to 10 radiation monitors installed in Kanazawa and Komatsu cities, Ishikawa Prefecture, Japan, where low-charge-center winter thunderstorms frequently occur. During four winter seasons from October 2016 to April 2020, in total 70 gamma-ray glows, minute-lasting bursts of gamma rays originating from thunderclouds, were detected. Their average duration is 58.9 sec. Among the detected events, 77% were observed in nighttime. The gamma-ray glows can be classified into temporally-symmetric, temporally-asymmetric, and lightning-terminated types based on their count-rate histories. An averaged energy spectrum of the gamma-ray glows is well fitted with a power-law function with an exponential cutoff, whose photon index, cutoff energy, and flux are $0.613\pm0.009$, $4.68\pm0.04$ MeV, and $(1.013\pm0.003)\times10^{-5}$ erg cm$^{-2}$ s$^{-1}$ (0.2-20.0MeV), respectively. The present paper provides the first catalog of gamma-ray glows and their statistical analysis detected during winter thunderstorms in the Kanazawa and Komatsu areas., Comment: 34 pages, 29 figures, accepted for publication in Physical Review Research

Published
2021

12. Sign of hard X-ray pulsation from the gamma-ray binary system LS 5039

Author

Yoneda, Hiroki, Makishima, Kazuo, Enoto, Teruaki, Khangulyan, Dmitry, Matsumoto, Takahiro, and Takahashi, Tadayuki

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

To understand the nature of the brightest gamma-ray binary system LS 5039, hard X-ray data of the object, taken with the Suzaku and NuSTAR observatories in 2007 and 2016, respectively, were analyzed. The two data sets jointly gave tentative evidence for a hard X-ray periodicity, with a period of $\sim 9$ s and a period increase rate by $\sim 3 \times 10^{-10}$ s s$^{-1}$. Therefore, the compact object in LS 5039 is inferred to be a rotating neutron star, rather than a black hole. Furthermore, several lines of arguments suggest that this object has a magnetic field of several times $\sim 10^{10}$ T, two orders of magnitude higher than those of typical neutron stars. The object is hence suggested to be a magnetar, which would be the first to be found in a binary. The results also suggest that the highly efficient particle acceleration process, known to be operating in LS 5039, emerges through interactions between dense stellar winds from the massive primary star, and ultra-strong magnetic fields of the magnetar., Comment: 8 pages, 3 figures, 1 table, accepted for publication in PRL

Published
2020
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13. Thundercloud Project: Exploring high-energy phenomena in thundercloud and lightning

Author

Yuasa, Takayuki, Wada, Yuuki, Enoto, Teruaki, Furuta, Yoshihiro, Tsuchiya, Harufumi, Hisadomi, Shohei, Tsuji, Yuna, Okuda, Kazufumi, Matsumoto, Takahiro, Nakazawa, Kazuhiro, Makishima, Kazuo, Miyake, Shoko, and Ikkatai, Yuko

Subjects
Physics - Atmospheric and Oceanic Physics, Physics - Instrumentation and Detectors
Abstract

We designed, developed, and deployed a distributed sensor network aiming at observing high-energy ionizing radiation, primarily gamma rays, from winter thunderclouds and lightning in coastal areas of Japan. Starting in 2015, we have installed, in total, more than 15 units of ground-based detector system in Ishikawa Prefecture and Niigata Prefecture, and accumulated 551 days of observation time in four winter seasons from late 2015 to early 2019. In this period, our system recorded 51 gamma-ray radiation events from thundercloud and lightning. Highlights of science results obtained from this unprecedented amount of data include the discovery of photonuclear reaction in lightning which produces neutrons and positrons along with gamma rays, and deeper insights into the life cycle of a particle-acceleration and gamma-ray-emitting region in a thundercloud. The present paper reviews objective, methodology, and results of our experiment, with a stress on its instrumentation., Comment: 31 pages, 20 figures, accepted for publication in Progress of Theoretical and Experimental Physics

Published
2020

14. Downward Terrestrial Gamma-ray Flash observed in Winter Thunderstorm

Author

Wada, Yuuki, Enoto, Teruaki, Nakazawa, Kazuhiro, Furuta, Yoshihiro, Yuasa, Takayuki, Nakamura, Yoshitaka, Morimoto, Takeshi, Matsumoto, Takahiro, Makishima, Kazuo, and Tsuchiya, Harufumi

Subjects
Physics - Atmospheric and Oceanic Physics, Astrophysics - High Energy Astrophysical Phenomena, High Energy Physics - Phenomenology
Abstract

During a winter thunderstorm on 2017 November 24, a strong burst of gamma rays with energies up to $\sim$10~MeV was detected coincident with a lightning discharge, by scintillation detectors installed at Kashiwazaki-Kariwa Nuclear Power Station at sea level in Japan. The burst had a sub-second duration, which is suggestive of photoneutron productions. The leading part of the burst was resolved into four intense gamma-ray bunches, each coincident with a low-frequency radio pulse. These bunches were separated by 0.7--1.5~ms, with a duration of $\ll$1~ms each. Thus, the present burst may be considered as a ``downward" terrestrial gamma-ray flash (TGF), which is analogous to up-going TGFs observed from space. Although the scintillation detectors were heavily saturated by these bunches, the total dose associated with them was successfully measured by ionization chambers, employed by nine monitoring posts surrounding the power plant. From this information and Monte Carlo simulations, the present downward TGF is suggested to have taken place at an altitude of 2500 $\pm$ 500~m, involving $8^{+8}_{-4} \times 10^{18}$ avalanche electrons with energies above 1~MeV. This number is comparable to those in up-going TGFs., Comment: 6 pages, 4 figures, accepted for publication in Physical Review Letters

Published
2019
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16. Mapping Observation Project of High-Energy Phenomena during Winter Thunderstorms in Japan

Author

Wada, Yuuki, Enoto, Teruaki, Furuta, Yoshihiro, Nakazawa, Kazuhiro, Yuasa, Takayuki, Matsumoto, Takahiro, Umemoto, Daigo, makishima, Kazuo, Tsuchiya, Harufumi, and collaboration, the GROWTH

Subjects
Physics - Atmospheric and Oceanic Physics, Physics - Instrumentation and Detectors
Abstract

The Gamma-Ray Observation of Winter Thunderclouds (GROWTH) collaboration has been performing observation campaigns of high-energy radiation in coastal areas of Japan Sea. Winter thunderstorms in Japan have unique characteristics such as frequent positive-polarity discharges, large discharge current, and low cloud bases. These features allow us to observe both long-duration gamma-ray bursts and lightning-triggered short-duration bursts at sea level. In 2015, we started a mapping observation project using multiple detectors at several new observation sites. We have developed brand-new portable gamma-ray detectors and deployed in the Kanazawa and Komatsu areas as well as the existing site at Kashiwazaki. During three winter seasons from 2015, we have detected 27 long-duration bursts and 8 short-duration bursts. The improved observation network in Kashiwazaki enables us to discover that the short-duration bursts are attributed to atmospheric photonuclear reactions triggered by a downward terrestrial gamma-ray flash. Collaborating with electric-field and radio-band measurements, we have also revealed a relation between abrupt termination of a long-duration burst and a lightning discharge. We demonstrate that the mapping observation project has been providing us clues to understand high-energy atmospheric phenomena associated with thunderstorm activities., Comment: 10 pages, 9 figures, to appear in TEPA (Thunderstorms and Elementary Particle Acceleration) 2018 conference proceedings

Published
2018

19. Safety of the oral factor XIa inhibitor asundexian compared with apixaban in patients with atrial fibrillation (PACIFIC-AF): a multicentre, randomised, double-blind, double-dummy, dose-finding phase 2 study

Author

Auer, Johann, Hubauer, Martin, Pandzic, Sead, Preishuber, Eva, Primus-Grabscheit, Carina, Reitgruber, Dietmar, Schmalzer, Florian, Adlbrecht, Christopher, Schober, Andreas, Hajos, Johannes, Keil, Christoph, Schratter, Alexandra, Frick, Matthias, Benda, Magdalena Anna, Mächler, Maximilian, Mutschlechner, Beatrix, Saely, Christoph, Sprenger, Lukas, Lichtenauer, Michael, Eber, Miriam, Hoppe, Uta, Kolbitsch, Tobias, Jirak, Peter Michael, Mirna, Moritz, Schönbauer, Robert, Bergler-Klein, Jutta, Hengstenberg, Christian, Stojkovic, Stefan, Scherr, Daniel, Manninger-Wünscher, Martin, Rohrer, Ursula, Stühlinger, Markus, Schgoer, Wilfried, Schwarzl, Jana, Pürerfellner, Helmut, Derndorfer, Michael, Ebner, Christian, Eder, Veronika, Kollias, Georgios, Sturmberger, Thomas, Sieghartsleitner, Stefan, Vijgen, Johan, Koopman, Peter, Dujardin, Karl, Anné, Wim, De Ceuninck, Michel, Tavernier, Rene, Duytschaever, Mattias, Knecht, Sébastien, Missault, Luc, Vandekerckhove, Yves, Rossenbacker, Tom, Ector, Bavo, Charlier, Filip, Debruyne, Philippe, Dewilde, Willem, Janssens, Luc, Roosen, John, Vankelecom, Bart, Heidbuchel, Hein, Delesie, Michiel, Vervoort, Gert, Rombouts, Hans, Vanassche, Thomas, Engelen, Matthias, Verhamme, Peter, Willems, Rik, Constance, Christian, Pranno, Nicolas, Cox, Jafna, Bata, Iqbal, Macle, Laurent, Aguilar, Martin, Tourigny, Julia Cadrin, Dubuc, Marc, Dyrda, Katia, Guerra, Peter, Khairy, Paul, Mondésert, Blandine, Rivard, Léna, Roy, Denis, Tadros, Rafik, Talajic, Mario, Thibault, Bernard, Nault, Isabelle, Blier, Louis, Champagne, Jean, Molin, Franck, O'Hara, Gilles, Philippon, François, Plourde, Benoit, Sarrazin, Jean-François, Steinberg, Christian, Coufal, Zdenek, Balazsik, David, Mikulica, Michal, Zapeca, Jakub, Cermak, Ondrej, Drasnar, Tomas, Falc, Matej, Hornof, Josef, Racz, Blazej, Weissova, Danica, Linkova, Hana, Paskova, Eva, Petr, Robert, Sirakova, Andrea, Kettner, Jiri, Benak, Ales, Holek, Martin, Podpera, Ivo, Podperova, Monika, Vancura, Vlastimil, Jandik, Tomas, Smid, Jiri, Dedek, Vratislav, Banik, Jan, Durdil, Vaclav, Hnat, Tomas, Lellouche, Nicolas, Rouffiac, Ségolène, Taldir, Guillaume, Bridonneau, Valentin, Couffon, Philippe, Daudin, Magalie, Hamon, Cécile, Lacaze, Jonathan, Quentin, Anne, Thebault, Christophe, Boiffard, Emmanuel, Billon, Olivier, Miette, Fabien, Pouliquen, Hervé, Turlotte, Guillaume, Gorka, Hervé, Albert, Franck, Bayle, Sandrine, Bensaid, Reda, Dasoveanu, Madalina, Demichili, Thibaud, Dutoiu, Teodora, Khalil, Cliff, Loghin, Caterina, Range, Grégoire, Roussel, Laurent, Socié, Pierre, Thuaire, Christophe, Extramiana, Fabrice, Algalarrondo, Vincent, Boughanmi, Haten, El Mansour, Noreddine, Mohammad, Usman, Sellier, Romain, Elbaz, Meyer, Laperche, Clémence, Maury, Philippe, Kiss, Robert, Borsanyi, Tunde, Gingl, Zoltan, Polgar, Balaza, Benczur, Bela, Bodor, Alexandra, Hepp, Tamas, Malati, Eva, Nagy, Laszlo, Erdei, Norbert, Kapus, Jozsef, Kapus, Katalin, Toth, Brigitta, Matoltsy, Andras, Kiss, Tunde, Merkely, Bela, Herczeg, Szilvia, Kiss, Orsolya, Sallo, Zoltan, Toth, Kalman, Habon, Tamas, Rabai, Miklos, Totsimon, Kinga, Zilahi, Zsolt, Bencze, Gabriella, Santa, Janos, Aradi, Daniel, Kelemen, Barbara, Bolognese, Leonardo, Nesti, Martina, Notarstefano, Pasquale Giovanni, D'Orazio, Simona, Cosmi, Franco, Becattini, Cecilia, Agnelli, Giancarlo, Broccatelli, Belinda, Mosconi, Maria Giulia, Paciaroni, Maurizio, Urbini, Chiara, Parato, Vito Maurizio, Notaristefani, Camilla, Scarano, Michele, Ameri, Pietro, Ghigliotti, Giorgio, Guglielmi, Giulia, Lotti, Roberta, Merlo, Andrea Carlo, Muiesan, Maria Lorenza, Abondio, Andrea, Berasi, Caterina, Mattiuzzo, Elena, Mutti, Claudio, Salvetti, Massimo, Pignatelli, Pasquale, Menichelli, Danilo, Pastori, Daniele, Tamiya, Eiji, Matsumoto, Takahiro, Takabe, Tomosato, Yamamoto, Shoichi, Yamashita, Haruyo, Higashiue, Shinichi, Furuya, Onichi, Hiramatsu, Norihiko, Kasuga, Kensuke, Kojima, Saburo, Komooka, Masatoshi, Kuroyanagi, Satoshi, Matsuura, Makoto, Takemoto, Tetsushi, Yamamoto, Shuji, Saito, Katusmi, Abe, Takuro, Ishida, Issei, Iwanami, Yuji, Kataoka, Shohei, Moriyama, Tetsu, Murohashi, Akira, Sasaki, Akihito, Nakamura, Yuichiro, Ueno, Tetsuya, Shimane, Akira, Hamana, Tomoyo, Ichibori, Hirotoshi, Inoue, Tomohiro, Itoh, Mitsuaki, Iwane, Seigo, Kawai, Hiroya, Kokawa, Tatsuya, Masumoto, Akiko, Matsuo, Koki, Miyata, Taishi, Nakano, Shinsuke, Oishi, Shogo, Onishi, Tetsuari, Sawada, Takahiro, Saito, Takayuki, Shoda, Mitsuhiko, Takahashi, Nobuyuki, Takaya, Tomofumi, Taniguchi, Yasuyo, Tsukamoto, Shota, Tsukishiro, Yasue, Tsukiyama, Yoshiro, Tsunamoto, Hiroshi, Uzu, Kenzo, Yamamoto, Hiroyuki, Yamamoto, Tetsuya, Yokoi, Kiminobu, Yoshida, Chiaki, Watanabe, Nobuhiro, Betsuyaku, Tetsuo, Adachi, Kumiko, Awane, Kouichi, Goto, Daisuke, Sakakibara, Mamoru, Watanabe, Masashi, Ueno, Hideki, Hiroe, Yoshitaka, Matsuo, Koshi, Ayata, Kenji, Fukuda, Ko, Hata, Yoshiki, Hashimoto, Katsushi, Matsumi, Hiroaki, Nikaido, Akira, Okamoto, Shuichi, Sime, Iveta, Stirna, Valters, Reinholde, Ilze, Hansone, Silvija, Kozlovska, Anita, Romanova, Janina, Klincare, Dace, Pontaga, Natalja, Dirmans, Igors, Kalnins, Artis, Upite, Dana, Gersamija, Arcils, Teleznikovs, Arturs, Rozkova, Nadezda, Safro, Jelena, Anguera Camós, Ignasi, Domenico Dallaglio, Paolo, Salguero Bodes, Rafael, Arnbas, Fernando, Borrego, Luis, Marco, Alvaro, Jimenez, Javier Ramos, Gómez-Doblas, Juan José, Pérez Cabeza, Alejandro, Ferreira Gonzålez, Ignacio, Limeres Freire, Javier, Lopez Grau, Merce, Viñolas Prat, Xavier, Moreno Weidmann, Zoraida, Guerra Ramos, Jose Maria, Alonso Martin, Maria Concepcion, Campos Garcia, Bieito, Mogro Carranza, Javier Mauricio, Mendez Zurita, Francisco Javier, Rodriguez Font, Enrique, Gonzales Matos, Carlos Eduardo, García Hernando, Víctor, Lindholm, Carl-Johan, Thulin, Jörgen, Wallén, Håkan, Hagwall, Kristina, Eliasson, Ken, Lundvall, Martin, Olsson, Jens, Kjellman, Björn, Lind, Markus, Johansson, Lars, Svedberg, Niclas, Berglund, Stefan, Söderberg, Julia, Zedigh, Christer, Mooe, Thomas, Axelsson, Mattias, Binsell, Emil, Huber, Daniel, Müller, Christian, Danier, Isabelle, Kühne, Michael, Okamura, Bernhard, Schoepfer, Hadrien, Simmen, Cornelia, Reichlin, Tobias, Chollet, Laurève, Lam, Anna, Wittmer, Severin, Rickli, Hans, Gall, Christian, Hametner, Greta, Intorp, Stephanie, Luescher, Daniel, Haegeli, Laurent, Berg, Jan Christopher, Ebrahimi, Ramin, Auricchio, Angelo, Crljenica, Carmela, Moccetti, Tizziano, Monti, Cristina, Pasotti, Elena, Petrova, Iveta, Rossi, Mariagrazia, Mach, François, Namdar, Mehdi, de Groot, Joris, Proost, Virginnio, Neefs, Joline, Linz, Dominik, van Stipdonk, Twan, den Uijl, Dennis, Alings, Marco, Schaap, Jeroen, Segers, Dolf, Wouters, Noemi, Bartels, Louis, Tieleman, Robert, Pisters, Ron, de Vries, Tim, Selig, Jaap, Kuijper, Aaf, Bot, Pieter, Keijzers, Mitran, Verdel, Gerardus, Tukkie, Raymond, van den Bos, Ewout, Kauer, Floris, Oemrawsingh, Rohit, Stevenhagen, Jeroen, van Es, Jan, Lip, Gregory, Gupta, Dhiraj, Kotalczyk, Agnieszka, Gunstone, Anthony, Brixey, Richard David, Gorog, Diana, Dinarvand, Danial, Gue, Ying, Kanji, Rahim, Memtsas, Vassilios, Senior, Roxy, Bioh, Gabriel, Wong, Yuk-Ki, Child, Nick, Piccini, Jonathan P, Caso, Valeria, Connolly, Stuart J, Fox, Keith A A, Oldgren, Jonas, Jones, W Schuyler, Gorog, Diana A, Durdil, Václav, Viethen, Thomas, Neumann, Christoph, Mundl, Hardi, and Patel, Manesh R

Published
2022
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24. Risk factors for lenvatinib‐induced palmar‐plantar erythrodysesthesia syndrome in patients with hepatocellular carcinoma: A retrospective study.

Author

Uekusa, Shusuke, Nemoto, Maho, Hanai, Yuki, Nakashin, Misaki, Yanagino, Sachiko, Arita, Yoshiki, Matsumoto, Takahiro, Wakui, Noritaka, Nagai, Hidenari, Higai, Koji, and Matsuo, Kazuhiro

Subjects
PROTEIN-tyrosine kinase inhibitors, ALKALINE phosphatase, HEPATOCELLULAR carcinoma, MULTIVARIATE analysis, PATHOLOGICAL laboratories, HAND-foot syndrome
Abstract

Aim: Lenvatinib mesylate (LEN) is an oral tyrosine kinase inhibitor used to treat various cancers, including hepatocellular carcinoma (HCC). HCC treatment with LEN is associated with a very high incidence of adverse events. This study was aimed at investigating the incidence of LEN‐induced palmar‐planter erythrodysesthesia syndrome (PPES) and its relationship with patient demographics by analyzing clinical laboratory data of LEN‐treated patients with HCC. Methods: This was a single‐centre, retrospective study of patients with HCC who received LEN between April 19, 2018, and September 30, 2020. The observation period was from 1 week before the start of LEN administration to 1 month after the end of administration. Results: Overall, 75 patients with HCC were enrolled. LEN‐induced PPES was found in 48.0% (36/75 patients). In these patients, alkaline phosphatase (ALP), γ‐Glutamyl transpeptidase (γ‐GTP) and monocytes (MONO) were significantly high (ALP: p = 1.32 × 10−3, γ‐GTP: p = 4.25 × 10−3 and MONO: p = 0.013). The cut off values of ALP, γ‐GTP and MONO for LEN‐induced PPES were estimated at 573 U/L, 89 U/L, and 310 counts/μL, respectively. In the multivariate analysis, γ‐GTP and MONO were independent risk factors for LEN‐induced PPES. Conclusions: High γ‐GTP and high MONO were risk factors for LEN‐induced PPES. [ABSTRACT FROM AUTHOR]

Published
2024
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36. Establishing a nanoimprint lithography ecosystem

Author

Tanaka, Hideo, primary, Hiura, Mitsuru, additional, Suzaki, Yoshio, additional, Yamamoto, Kiyohito, additional, Maruyama, Naoki, additional, Kimura, Atsushi, additional, Matsumoto, Takahiro, additional, Yamamoto, Kenji, additional, and Takabayashi, Yukio, additional

Published
2023
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43. Brain Masculinization Requires Androgen Receptor Function

Author

Sato, Takashi, Matsumoto, Takahiro, Kawano, Hirotaka, Watanabe, Tomoyuki, Uematsu, Yoshikatsu, Sekine, Keisuke, Fukuda, Toru, Aihara, Ken-ichi, Krust, Andrée, Yamada, Takashi, Nakamichi, Yuko, Yamamoto, Yoko, Nakamura, Takashi, Yoshimura, Kimihiro, Yoshizawa, Tatsuya, Metzger, Daniel, Chambon, Pierre, and Kato, Shigeaki

Published
2004

48. Suppressive Function of Androgen Receptor in Bone Resorption

Author

Kawano, Hirotaka, Sato, Takashi, Yamada, Takashi, Matsumoto, Takahiro, Sekine, Keisuke, Watanabe, Tomoyuki, Nakamura, Takashi, Fukuda, Toru, Yoshimura, Kimihiro, Yoshizawa, Tatsuya, Aihara, Ken-ichi, Yamamoto, Yoko, Nakamichi, Yuko, Metzger, Daniel, Chambon, Pierre, Nakamura, Kozo, Kawaguchi, Hiroshi, and Kato, Shigeaki

Published
2003

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