171 results on '"Matsuki, Shunji"'
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2. Effect of γ-tocopherol supplementation on premenstrual symptoms and natriuresis: a randomized, double-blind, placebo-controlled study
3. Single- and Multiple-Dose Pharmacokinetics and Safety of Vilaprisan in Healthy Postmenopausal Japanese Women: A Randomized Clinical Trial
4. Comparative pharmacokinetics of maxacalcitol in healthy Taiwanese and Japanese subjects
5. Effects of rifampicin on the pharmacokinetics and safety of carotegrast methyl in healthy subjects: A randomized 2 × 2 crossover study
6. Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers
7. Evaluation of the potential drug‐drug interactions of carotegrast methyl with midazolam, prednisolone, or atorvastatin in healthy adults
8. The Effect of Drug Content Reduction on the In Vitro and In Vivo Properties of Levonorgestrel-Releasing Intravaginal Rings
9. Effects of magnesium oxide on pharmacokinetics of L-dopa/carbidopa and assessment of pharmacodynamic changes by a model-based simulation
10. Effects of Rifampicin on the Pharmacokinetics and Safety of Carotegrast Methyl in Healthy Subjects: A Randomized 2 x 2 Crossover Study
11. Effect of itraconazole and fluconazole on the pharmacokinetics of valemetostat: An open‐label, phase I study in healthy subjects
12. Safety, Tolerability, and Pharmacokinetics of Valemetostat Tablets and the Effect of Food on Valemetostat Pharmacokinetics in Healthy Subjects: Two Phase 1 Studies
13. Involvement of Organic Cation Transporters in the Kinetics of Trimethylamine N-oxide
14. Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP
15. Evaluation of the potential drug–drug interactions of carotegrast methyl with midazolam, prednisolone or atorvastatin in healthy adults.
16. Safety, Tolerability, and Pharmacokinetics of Valemetostat Tablets and the Effect of Food on Valemetostat Pharmacokinetics in Healthy Subjects: Two Phase 1 Studies.
17. Pharmacokinetic Bioequivalence, Safety, and Immunogenicity of DMB-3111, a Trastuzumab Biosimilar, and Trastuzumab in Healthy Japanese Adult Males: Results of a Randomized Trial
18. BACE1 Inhibitor Lanabecestat (AZD3293) in a Phase 1 Study of Healthy Japanese Subjects: Pharmacokinetics and Effects on Plasma and Cerebrospinal Fluid Aβ Peptides
19. Evaluation of Assay Sensitivity and the Concentration-Effect Relationship of Moxifloxacin in a QT/QTc Study in Japan
20. Single- and Multiple-Dose Pharmacokinetics and Safety of Vilaprisan in Healthy Postmenopausal Japanese Women: A Randomized Clinical Trial
21. Effects of a reactive oxygen species generator, napabucasin (BBI608), on tolerability, safety, pharmacokinetics, and QT/QTc interval in healthy volunteers
22. Pharmacokinetic and bioequivalence evaluation of single-tablet and separate-tablet regimens for once-daily cobicistat-boosted elvitegravir in healthy Japanese male subjects: A randomized, two-way crossover study
23. A comparative pharmacokinetic and pharmacodynamic study of FSK0808 versus reference filgrastim after repeated subcutaneous administration in healthy Japanese men
24. Cerebrospinal Fluid Protein Concentration in Healthy Older Japanese Volunteers
25. Effects of a protein-rich drink or a standard meal on the pharmacokinetics of elvitegravir, cobicistat, emtricitabine and tenofovir in healthy Japanese male subjects: A randomized, three-way crossover study
26. Cerebrospinal Fluid Protein Concentration in Japanese Healthy Older Volunteers
27. Statistical Analysis of the Axillary Temperatures Measured by a Predictive Electronic Thermometer in Healthy Japanese Adults
28. SARS-CoV-2 Seroprevalence among Healthcare Workers in General Hospitals and Clinics in Japan
29. Mechanisms of Pharmacokinetic Enhancement Between Ritonavir and Saquinavir; Micro/Small Dosing Tests Using Midazolam (CYP3A4), Fexofenadine (p-Glycoprotein), and Pravastatin (OATP1B1) as Probe Drugs
30. A Phase 1, Randomized, Placebo‐Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Subcutaneous Tezepelumab in Healthy Japanese Men
31. Choledochal Cyst Diagnosed and Conservatively Treated during Pregnancy
32. The Effect of Erythromycin and Clarithromycin on the Pharmacokinetics of Intravenous Digoxin in Healthy Volunteers
33. The effect of pregnancy on cytochrome P4501A2, xanthine oxidase, and N-acetyltransferase activities in humans
34. Pharmacokinetic Changes of Theophylline and Amikacin through the Menstrual Cycle in Healthy Women
35. Elucidation of N1-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters
36. Influence of ALDH2 polymorphisms on the effect of co-administration of quercetin with nitroglycerin on endothelial function
37. Effects of magnesium oxide on pharmacokinetics of L-dopa/carbidopa and assessment of pharmacodynamic changes by a model-based simulation
38. Clinical Drug-Drug Interaction Potential of BFE1224, Prodrug of Antifungal Ravuconazole, Using Two Types of Cocktails in Healthy Subjects
39. Safety, Pharmacodynamics and Pharmacokinetics of the Oral Selective Hypoxia-inducible Factor Prolyl Hydroxylase Inhibitor Molidustat in Japanese Healthy Subjects
40. Selection of spinal needles for cerebrospinal fluid collection in clinical trials
41. Circulating intestine-derived exosomal miR-328 in plasma, a possible biomarker for estimating BCRP function in the human intestines
42. P2-002: Assessment of The Safety, Tolerability, Pharmacokinetics, and Effects on Plasma and Cerebrospinal Fluid AB Peptides of AZD3293, a Novel Bace1 Inhibitor, in Healthy Japanese Adults
43. Efficacy of a novel phosphodiesterase inhibitor, E6005, in patients with atopic dermatitis: An investigator-blinded, vehicle-controlled study
44. Pharmacokinetic Bioequivalence, Safety, and Immunogenicity of DMB-3111, a Trastuzumab Biosimilar, and Trastuzumab in Healthy Japanese Adult Males: Results of a Randomized Trial
45. Pharmacokinetic and bioequivalence evaluation of single‐tablet and separate‐tablet regimens for once‐daily cobicistat‐boosted elvitegravir in healthy Japanese male subjects: A randomized, two‐way crossover study
46. Pharmacokinetics and pharmacodynamics of FSK0808 and Gran after single intravenous drip administration or single subcutaneous administration: comparative study in healthy Japanese adult male subjects
47. Evaluation of Methods for Safe Clinical Bioequivalence Study of High Dose Psychotropic Agents in Healthy Subjects: Pilot Study of Quetiapine Fumarate and Pramipexole Hydrochloride Hydrate
48. ASSESSMENT OF THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFECTS ON PLASMA AND CEREBROSPINAL FLUID AB PEPTIDES OF AZD3293, A NOVEL BACE1 INHIBITOR, IN HEALTHY JAPANESE ADULTS
49. 3. Conducting Phase 1 Study in Patient Subjects: Points to Consider
50. 3. PK/PD Study in Patients in Phase 1 Unit
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