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322 results on '"Matsubara, Kentaro"'

7. Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells

Author

Takeishi, Kazuki, Collin de l’Hortet, Alexandra, Wang, Yang, Handa, Kan, Guzman-Lepe, Jorge, Matsubara, Kentaro, Morita, Kazutoyo, Jang, Sae, Haep, Nils, Florentino, Rodrigo M., Yuan, Fangchao, Fukumitsu, Ken, Tobita, Kimimasa, Sun, Wendell, Franks, Jonathan, Delgado, Evan R., Shapiro, Erik M., Fraunhoffer, Nicolas A., Duncan, Andrew W., Yagi, Hiroshi, Mashimo, Tomoji, Fox, Ira J., and Soto-Gutierrez, Alejandro

Published
2020
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9. Impact of Stent Graft Design on External Iliac Artery Limb Occlusion Rates After Endovascular Aneurysm Repair: Post-hoc Analysis of a Japanese Multicentre Database

Author

Shintani, Tsunehiro, Obara, Hideaki, Matsubara, Kentaro, Hayashi, Keita, Hayashi, Masanori, Ono, Shigeshi, Shimogawara, Tatsuya, Shibutani, Shintaro, Watada, Susumu, Sekimoto, Yasuhito, Uchida, Norio, Asami, Atsunori, Fujii, Taku, Harada, Hirohisa, Fujimura, Naoki, Sato, Yasunori, and Kitagawa, Yuko

Published
2019
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11. Characteristics, Antithrombotic Patterns, and Prognostic Outcomes in Claudication and Critical Limb-Threatening Ischemia Undergoing Endovascular Therapy.

Author

Kawarada, Osami, Zen, Kan, Hozawa, Koji, Obara, Hideaki, Matsubara, Kentaro, Yamamoto, Yoshito, Doijiri, Tatsuki, Tamai, Nozomu, Ito, Shigenori, Higashimori, Akihiro, Kawasaki, Daizo, Doi, Hideki, Matsushita, Kensuke, Tsukahara, Kengo, Noda, Katsuo, Shimpo, Masahisa, Tsuda, Yuki, Sonoda, Shinjo, Taniguchi, Takuya, and Waseda, Katsuhisa

Abstract

Purpose: The underlying difference between intermittent claudication (IC) and critical limb-threatening ischemia (CLTI) still remains unclear. This prospective multicenter observational study aimed to clarify differences in clinical features and prognostic outcomes between IC and CLTI, and prognostic factors in patients undergoing endovascular therapy (EVT). Materials and Methods: A total of 692 patients with 808 limbs were enrolled from 20 institutions in Japan. The primary measurements were the 3-year rates of major adverse cardiovascular event (MACE) and reintervention. Results: Among patients, 79.0% had IC and 21.0% had CLTI. Patients with CLTI were more frequently women and more likely to have impaired functional status, undernutrition, comorbidities, hypercoagulation, hyperinflammation, distal artery disease, short single antiplatelet and long anticoagulation therapies, and late cilostazol than patients with IC. Aortoiliac and femoropopliteal diseases were dominant in patients with IC and infrapopliteal disease was dominant in patients with CLTI. Patients with CLTI underwent less frequently aortoiliac intervention and more frequently infrapopliteal intervention than patients with IC. Longitudinal change of ankle-brachial index (ABI) exhibited different patterns between IC and CLTI (pinteraction=0.002), but ABI improved after EVT both in IC and in CLTI (p<0.001), which was sustained over time. Dorsal and plantar skin perfusion pressure in CLTI showed a similar improvement pattern (pinteraction=0.181). Distribution of Rutherford category improved both in IC and in CLTI (each p<0.001). Three-year MACE rates were 20.4% and 42.3% and 3-year reintervention rates were 22.1% and 46.8% for patients with IC and CLTI, respectively (log-rank p<0.001). Elevated D-dimer (p=0.001), age (p=0.043), impaired functional status (p=0.018), and end-stage renal disease (p=0.019) were independently associated with MACE. After considering competing risks of death and major amputation for reintervention, elevated erythrocyte sedimentation rate (p=0.003) and infrainguinal intervention (p=0.002) were independently associated with reintervention. Patients with CLTI merely showed borderline significance for MACE (adjusted hazard ratio 1.700, 95% confidence interval 0.950–3.042, p=0.074) and reintervention (adjusted hazard ratio 1.976, 95% confidence interval 0.999–3.909, p=0.05). Conclusions: The CLTI is characterized not only by more systemic comorbidities and distal disease but also by more inflammatory coagulation disorder compared with IC. Also, CLTI has approximately twice MACE and reintervention rates than IC, and the underlying inflammatory coagulation disorder per se is associated with these outcomes. Clinical Impact: The underlying difference between intermittent claudication (IC) and critical limb-threatening ischemia (CLTI) still remains unclear. This prospective multicenter observational study, JPASSION study found that CLTI was characterized not only by more systemic comorbidities and distal disease but also by more inflammatory coagulation disorder compared to IC. Also, CLTI had approximately twice major adverse cardiovascular event (MACE) and reintervention rates than IC. Intriguingly, the underlying inflammatory coagulation disorder per se was independently associated with MACE and reintervention. Further studies to clarify the role of anticoagulation and anti-inflammatory therapies will contribute to the development of post-interventional therapeutics in the context of peripheral artery disease. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Impact of wound management strategies after revascularization for chronic limb-threatening ischemia

Author

Shintani, Tsunehiro, primary, Obara, Hideaki, additional, Matsubara, Kentaro, additional, Hayashi, Masanori, additional, Kita, Hidenori, additional, Ono, Shigeshi, additional, Watada, Susumu, additional, Kikuchi, Naoya, additional, Sekimoto, Yasuhito, additional, Torizaki, Yukiko, additional, Asami, Atsunori, additional, Fujii, Taku, additional, Hayashi, Keita, additional, Harada, Hirohisa, additional, Fujimura, Naoki, additional, Hosokawa, Kyousuke, additional, Nakatani, Eiji, additional, and Kitagawa, Yuko, additional

Published
2023
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14. Noninvasive graft monitoring using donor‐derived cell‐free DNA in Japanese liver transplantation

Author

Kanamori, Hiroki, primary, Yamada, Yohei, additional, Ito, Yoko, additional, Shirosaki, Koji, additional, Yamagishi, Satoko, additional, Yutaro, Maeda, additional, Kudo, Yumi, additional, Umeyama, Tomoshige, additional, Takahashi, Nobuhiro, additional, Kato, Mototoshi, additional, Hasegawa, Yasushi, additional, Matsubara, Kentaro, additional, Shinoda, Masahiro, additional, Obara, Hideaki, additional, Irie, Rie, additional, Tsujikawa, Hanako, additional, Okita, Hajime, additional, Nguyen, Phuong Thanh, additional, Saigo, Kenichi, additional, Mitsunaga, Shigeki, additional, Inoue, Ituro, additional, Kitagawa, Yuko, additional, and Kuroda, Tatsuo, additional

Published
2023
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17. Clinical features of irreversible rejection after allogeneic uterus transplantation in cynomolgus macaques

Author

Kisu, Iori, Emoto, Katsura, Masugi, Yohei, Yamada, Yohei, Matsubara, Kentaro, Obara, Hideaki, Matoba, Yusuke, Banno, Kouji, Kato, Yojiro, Saiki, Yoko, Itagaki, Iori, Kawamoto, Ikuo, Iwatani, Chizuru, Murase, Mitsuru, Nakagawa, Takahiro, Tsuchiya, Hideaki, Ishigaki, Hirohito, Urano, Hiroyuki, Ema, Masatsugu, Ogasawara, Kazumasa, Aoki, Daisuke, Nakagawa, Kenshi, and Shiina, Takashi

Published
2020
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18. Noninvasive graft monitoring using donor‐derived cell‐free DNA in Japanese liver transplantation.

Author

Kanamori, Hiroki, Yamada, Yohei, Ito, Yoko, Shirosaki, Koji, Yamagishi, Satoko, Maeda, Yutaro, Kudo, Yumi, Umeyama, Tomoshige, Takahashi, Nobuhiro, Kato, Mototoshi, Hasegawa, Yasushi, Matsubara, Kentaro, Shinoda, Masahiro, Obara, Hideaki, Irie, Rie, Tsujikawa, Hanako, Okita, Hajime, Nguyen, Phuong Thanh, Saigo, Kenichi, and Mitsunaga, Shigeki

Subjects
CELL-free DNA, LIVER transplantation, SINGLE nucleotide polymorphisms, ALANINE aminotransferase, ASPARTATE aminotransferase, CIRCULATING tumor DNA
Abstract

Aim: To evaluate the use of donor‐derived cell‐free DNA (dd‐cfDNA) in diagnosing graft injuries in Japanese liver transplantation (LTx), including family‐related living donors. Methods: A total of 321 samples from 10 newly operated LTx recipients were collected to monitor the early dynamics of dd‐cfDNA levels after LTx. Fifty‐five samples from 55 recipients were collected during protocol biopsies (PB), whereas 36 samples from 27 recipients were collected during event biopsies, consisting of 11 biopsy‐proven acute rejection (AR), 20 acute dysfunctions without rejection (ADWR), and 5 chronic rejections. The levels of dd‐cfDNA were quantified using a next‐generation sequencer based on single nucleotide polymorphisms. Results: The dd‐cfDNA levels were elevated significantly after LTx, followed by a rapid decline to the baseline in patients without graft injury within 30 days post‐LTx. The dd‐cfDNA levels were significantly higher in the 11 samples obtained during AR than those obtained during PB (p < 0.0001), which decreased promptly after treatment. The receiver operator characteristic curve analysis of diagnostic ability yielded areas under the curve of 0.975 and 0.897 for AR (rejection activity index [RAI] ≥3) versus PB and versus non‐AR (ADWR + PB). The dd‐cfDNA levels during AR were elevated earlier and correlated more strongly with the RAI (r = 0.740) than aspartate aminotransferase/alanine aminotransferase. The dd‐cfDNA levels were neither associated with graft fibrosis based on histology nor the status of donor‐specific antibodies in PB samples. Conclusions: Donor‐derived cell‐free DNA serves as a sensitive biomarker for detecting graft injuries in LTx. Further large‐scale cohort studies are warranted to optimize its use in differentiating various post‐LTx etiologies. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Long-term Results of a Heparin-bonded Expanded Polytetrafluoroethylene Grafts for Above-the-knee Femoropopliteal Bypasses: A Japanese Prospective Multicenter Registry

Author

Fujimura, Naoki, primary, Obara, Hideaki, additional, Matsubara, Kentaro, additional, Toya, Naoki, additional, Isogai, Naoko, additional, Ogino, Hidemitsu, additional, Fujii, Taku, additional, Kudo, Toshifumi, additional, Kanaoka, Yuji, additional, Harada, Hirohisa, additional, Uchiyama, Hidetoshi, additional, Guntani, Atsushi, additional, Shimogawara, Tatsuya, additional, Shibutani, Shintaro, additional, and Ohki, Takao, additional

Published
2023
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30. Concurrent presentation of an intraductal tubulopapillary neoplasm and intraductal papillary mucinous neoplasm in the branch duct of the pancreas, with a superior mesenteric artery aneurysm: a case report

Author

Inomata, Kenta, Kitago, Minoru, Obara, Hideaki, Fujii-Nishimura, Yoko, Shinoda, Masahiro, Yagi, Hiroshi, Abe, Yuta, Hibi, Taizo, Matsubara, Kentaro, Oshima, Go, Sekimoto, Yasuhito, Inoue, Masazumi, Itano, Osamu, Sakamoto, Michiie, and Kitagawa, Yuko

Published
2018
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31. Characteristics, Antithrombotic Patterns, and Prognostic Outcomes in Claudication and Critical Limb-Threatening Ischemia Undergoing Endovascular Therapy

Author

Kawarada, Osami, primary, Zen, Kan, additional, Hozawa, Koji, additional, Obara, Hideaki, additional, Matsubara, Kentaro, additional, Yamamoto, Yoshito, additional, Doijiri, Tatsuki, additional, Tamai, Nozomu, additional, Ito, Shigenori, additional, Higashimori, Akihiro, additional, Kawasaki, Daizo, additional, Doi, Hideki, additional, Matsushita, Kensuke, additional, Tsukahara, Kengo, additional, Noda, Katsuo, additional, Shimpo, Masahisa, additional, Tsuda, Yuki, additional, Sonoda, Shinjo, additional, Taniguchi, Takuya, additional, Waseda, Katsuhisa, additional, Munehisa, Masato, additional, Taguchi, Eiji, additional, Kinjo, Tatsuya, additional, Sasaki, Yohei, additional, Yuba, Kenichiro, additional, Yamaguchi, Shinichiro, additional, Nakagami, Takuo, additional, Ayabe, Shinobu, additional, Sakamoto, Shingo, additional, Yagyu, Takeshi, additional, Ogata, Soshiro, additional, Nishimura, Kunihiro, additional, Motomura, Hisashi, additional, Noguchi, Teruo, additional, Ishihara, Masaharu, additional, Ogawa, Hisao, additional, and Yasuda, Satoshi, additional

Published
2022
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33. Rituximab Induction to Prevent the Recurrence of PSC After Liver Transplantation—The Lessons Learned From ABO-Incompatible Living Donor Liver Transplantation

Author

Yamada, Yohei, Hoshino, Ken, Fuchimoto, Yasushi, Matsubara, Kentaro, Hibi, Taizo, Yagi, Hiroshi, Abe, Yuta, Shinoda, Masahiro, Kitago, Minoru, Obara, Hideaki, Yagi, Takahito, Okajima, Hideaki, Kaido, Toshimi, Uemoto, Shinji, Suzuki, Tatsuya, Kubota, Keiichi, Yoshizumi, Tomoharu, Maehara, Yoshihiko, Inomata, Yukihiro, Kitagawa, Yuko, Egawa, Hiroto, and Kuroda, Tatsuo

Published
2018
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34. Successful living donor liver retransplantation for graft failure within 7 days due to acute de novo donor‐specific anti‐human leukocyte antigen antibody‐mediated rejection

Author

Yamada, Yohei, Hoshino, Ken, Mori, Teisaburo, Kawaida, Miho, Abe, Kiyotomo, Ishihama, Hideo, Shimizu, Takahiro, Takahashi, Nobuhiro, Matsubara, Kentaro, Hibi, Taizo, Abe, Yuta, Yagi, Hiroshi, Shimojima, Naoki, Shinoda, Masahiro, Kitago, Minoru, Obara, Hideaki, Fuchimoto, Yasushi, Kameyama, Kaori, Kitagawa, Yuko, and Kuroda, Tatsuo

Published
2018
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35. Long-term Outcomes of the Endurant and Excluder Stent Grafts for Endovascular Aneurysm Repair in a Japanese Cohort.

Author

Sekimoto, Yasuhito, Fujimura, Naoki, Matsubara, Kentaro, Uchida, Norio, Asami, Atsunori, Harada, Hirohisa, Shintani, Tsunehiro, Watada, Susumu, Ono, Shigeshi, Fujii, Taku, Shimogawara, Tatsuya, Hayashi, Keita, Hayashi, Masanori, Obara, Hideaki, and Kitagawa, Yuko

Abstract

Purpose: To compare the long-term outcomes of the most widely used third-generation stent grafts, the Endurant and Excluder stent grafts, in Japanese patients using a multicenter registry. Materials and Methods: A retrospective analysis of endovascular aneurysm repairs for abdominal aortic and iliac artery aneurysms using either the Endurant or the Excluder stent grafts from January 2012 to July 2019 at 10 Japanese hospitals was performed. Results: A total of 332 and 378 repairs using the Endurant and Excluder stent grafts, respectively, were analyzed. Although the patients' characteristics were generally similar in the two groups, the Endurant group exhibited significantly shorter (Endurant: 31.5±18.6 mm, Excluder: 37.4±21.0 mm; p<0.001), larger (Endurant: 22.4±4.2 mm, Excluder: 21.7±3.8 mm; p=0.029), and more reversed tapered (Endurant: 12.1%, Excluder: 5.8%; p=0.003) proximal necks. The incidence of instructions for use (IFU) violations was similar between the two groups (Endurant: 59.0%, Excluder: 54.5%; p=0.223). However, the Endurant group had significantly more proximal neck-related IFU violations (54.1% and 46.3%, respectively; p=0.039), more access-related IFU violations (8.1% and 4.0%, respectively; p=0.019), and fewer bilateral hypogastric artery embolizations (5.1% and 9.3%, respectively; p=0.035) compared with the Excluder group. The incidence of intraoperative (Endurant: 3.6%, Excluder: 3.7%; p=0.950) and perioperative complications (Endurant: 3.6%, Excluder: 3.4%, p=0.899) was equivalent in the two groups. However, there was a significantly higher incidence of postoperative type II endoleaks in the Excluder group (Endurant: 28%, Excluder: 46.0%, p<0.001). Aneurysm sac regression was more frequent in the Endurant group (Endurant: 40.7%, Excluder: 31.7%, p=0.013). The Endurant group also had significantly higher rates of sac increase (Endurant: 13.0%, Excluder: 7.7%, p=0.020). Kaplan-Meier curve and log-rank analyses revealed no statistical differences in late complications (p=0.868) and overall survival (p=0.926). Conclusions: There were no statistically significant differences between the Endurant and the Excluder stent grafts in terms of intraoperative, perioperative, and late complication rates; however, the anatomical characteristics of the patients were significantly different. [ABSTRACT FROM AUTHOR]

Published
2023
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39. Standardized upfront Glissonean approach and liver hanging maneuver reduces bile leakage from the hepatic hilum in living donors

Author

Hirukawa, Kazuya, primary, Masuda, Yuki, additional, Abe, Yuta, additional, Yagi, Hiroshi, additional, Ibuki, Sho, additional, Itano, Osamu, additional, Shinoda, Masahiro, additional, Kitago, Minoru, additional, Hasegawa, Yasushi, additional, Hori, Shutaro, additional, Tanaka, Masayuki, additional, Nakano, Yutaka, additional, Matsubara, Kentaro, additional, Obara, Hideaki, additional, Yamada, Yohei, additional, Kuroda, Tatsuo, additional, Hibi, Taizo, additional, and Kitagawa, Yuko, additional

Published
2022
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40. 1-Year Outcomes of Thromboendarterectomy vs Endovascular Therapy for Common Femoral Artery Lesions

Author

Nakama, Tatsuya, primary, Takahara, Mitsuyoshi, additional, Iwata, Yo, additional, Fujimura, Naoki, additional, Yamaoka, Terutoshi, additional, Suzuki, Kenji, additional, Obunai, Kotaro, additional, Tan, Michinao, additional, Shibata, Tsuyoshi, additional, Horie, Kazunori, additional, Sasaki, Shinya, additional, Akamatsu, Daijirou, additional, Takahashi, Hiroki, additional, Yamamoto, Yoshito, additional, Yasuto, Hoshino, additional, Aihara, Hideaki, additional, Uchiyama, Hidetoshi, additional, Kodama, Takahide, additional, Tabata, Minoru, additional, Ohara, Hideaki, additional, Matsubara, Kentaro, additional, Kamiya, Yuki, additional, Sekimoto, Yasuhito, additional, Igari, Kimihiro, additional, Umemoto, Tomoyuki, additional, Jujo, Kentaro, additional, Matsui, Akihiro, additional, Shintani, Yoshiaki, additional, Kotani, Shinsuke, additional, Hozawa, Koji, additional, Hideto, Yano, additional, Ueshima, Daisuke, additional, Ozaki, Dai, additional, Hayakawa, Naoki, additional, Doijiri, Tatsuki, additional, Tobita, Kazuki, additional, Shimogawara, Tatsuya, additional, Mouri, Shinsuke, additional, Araki, Hiroshi, additional, Yamauchi, Yasutaka, additional, Anzai, Hitoshi, additional, Shintani, Tsunehiro, additional, Hayashi, Masanori, additional, Kato, Tamon, additional, Shinozaki, Norihiko, additional, Banno, Hiroshi, additional, Kojima, Tai, additional, Fujihara, Masahiko, additional, Iida, Osamu, additional, Hata, Yosuke, additional, Kawasaki, Daizo, additional, Nakamura, Jun, additional, Kimura, Masayoshi, additional, Tsubakimoto, Yoshinori, additional, Yamaguchi, Shinichiro, additional, Ichihashi, Shigeo, additional, Tanaka, Hiroyuki, additional, Kobayashi, Taira, additional, Furuyama, Tadashi, additional, Morisaki, Koichi, additional, Makoto, Sugihara, additional, Imoto, Yuki, additional, Doi, Hideki, additional, Suematsu, Nobuhiro, additional, Ito, Hiroyuki, additional, Okadome, Jun, additional, Kyuragi, Ryoichi, additional, Ogata, Kenji, additional, Hayashi, Keita, additional, Fujii, Taku, additional, Isogai, Naoko, additional, and Karashima, Eiji, additional

Published
2022
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41. Long-term Outcomes of the Endurant and Excluder Stent Grafts for Endovascular Aneurysm Repair in a Japanese Cohort

Author

Sekimoto, Yasuhito, primary, Fujimura, Naoki, additional, Matsubara, Kentaro, additional, Uchida, Norio, additional, Asami, Atsunori, additional, Harada, Hirohisa, additional, Shintani, Tsunehiro, additional, Watada, Susumu, additional, Ono, Shigeshi, additional, Fujii, Taku, additional, Shimogawara, Tatsuya, additional, Hayashi, Keita, additional, Hayashi, Masanori, additional, Obara, Hideaki, additional, and Kitagawa, Yuko, additional

Published
2022
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42. sj-docx-1-cll-10.1177_09636897221089629 – Supplemental material for Adipose-Derived Mesenchymal Stromal/Stem Cell Line Prevents Hepatic Ischemia/Reperfusion Injury in Rats by Inhibiting Inflammasome Activation

Author

Chen, Kaili, Obara, Hideaki, Matsubara, Yumiko, Fukuda, Kazumasa, Yagi, Hiroshi, Ono-Uruga, Yukako, Matsubara, Kentaro, and Kitagawa, Yuko

Subjects
Medicine, Cell Biology
Abstract

Supplemental material, sj-docx-1-cll-10.1177_09636897221089629 for Adipose-Derived Mesenchymal Stromal/Stem Cell Line Prevents Hepatic Ischemia/Reperfusion Injury in Rats by Inhibiting Inflammasome Activation by Kaili Chen, Hideaki Obara, Yumiko Matsubara, Kazumasa Fukuda, Hiroshi Yagi, Yukako Ono-Uruga, Kentaro Matsubara and Yuko Kitagawa in Cell Transplantation

Published
2022
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43. sj-docx-2-cll-10.1177_09636897221089629 – Supplemental material for Adipose-Derived Mesenchymal Stromal/Stem Cell Line Prevents Hepatic Ischemia/Reperfusion Injury in Rats by Inhibiting Inflammasome Activation

Author

Chen, Kaili, Obara, Hideaki, Matsubara, Yumiko, Fukuda, Kazumasa, Yagi, Hiroshi, Ono-Uruga, Yukako, Matsubara, Kentaro, and Kitagawa, Yuko

Subjects
Medicine, Cell Biology
Abstract

Supplemental material, sj-docx-2-cll-10.1177_09636897221089629 for Adipose-Derived Mesenchymal Stromal/Stem Cell Line Prevents Hepatic Ischemia/Reperfusion Injury in Rats by Inhibiting Inflammasome Activation by Kaili Chen, Hideaki Obara, Yumiko Matsubara, Kazumasa Fukuda, Hiroshi Yagi, Yukako Ono-Uruga, Kentaro Matsubara and Yuko Kitagawa in Cell Transplantation

Published
2022
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45. Reappraisal of liver transplantation for erythropoietic protoporphyria: A deadly combination of disease recurrence and biliary complication

Author

Endo, Yutaka, primary, Hibi, Taizo, additional, Shinoda, Masahiro, additional, Obara, Hideaki, additional, Kitago, Minoru, additional, Yagi, Hiroshi, additional, Abe, Yuta, additional, Hasegawa, Yasushi, additional, Matsubara, Kentaro, additional, Hori, Shutaro, additional, Tanaka, Masayuki, additional, Makiuchi, Satomi, additional, Nakano, Yutaka, additional, Itano, Osamu, additional, Kuroda, Tatsuo, additional, and Kitagawa, Yuko, additional

Published
2022
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48. The hypotaurine-taurine pathway as an antioxidative mechanism in patients with acute liver failure

Author

Mizota, Takamasa, primary, Hishiki, Takako, additional, Shinoda, Masahiro, additional, Naito, Yoshiko, additional, Hirukawa, Kazuya, additional, Masugi, Yohei, additional, Itano, Osamu, additional, Obara, Hideaki, additional, Kitago, Minoru, additional, Yagi, Hiroshi, additional, Abe, Yuta, additional, Matsubara, Kentaro, additional, Suematsu, Makoto, additional, and Kitagawa, Yuko, additional

Published
2022
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50. Current management strategies for visceral artery aneurysms: an overview

Author

Yuko Kitagawa, Masanori Inoue, Hideaki Obara, and Matsubara Kentaro

Subjects
Laparoscopic surgery, medicine.medical_specialty, Visceral artery aneurysm, Computed Tomography Angiography, medicine.medical_treatment, Endovascular therapy, Review Article, 030204 cardiovascular system & hematology, Aneurysm, Ruptured, Asymptomatic, Inferior mesenteric artery, 03 medical and health sciences, Pseudoaneurysm, 0302 clinical medicine, Aneurysm, Celiac artery, Celiac Artery, Mesenteric Artery, Superior, medicine.artery, medicine, Retroperitoneal space, Humans, Superior mesenteric artery, Aneurysm rupture, business.industry, Endovascular Procedures, Correction, Mesenteric Artery, Inferior, General Medicine, medicine.disease, Viscera, medicine.anatomical_structure, Etiology, Surgery, Laparoscopy, Radiology, medicine.symptom, business, 030217 neurology & neurosurgery
Abstract

Visceral artery aneurysms (VAAs) are rare and affect the celiac artery, superior mesenteric artery, and inferior mesenteric artery, and their branches. The natural history of VAAs is not well understood as they are often asymptomatic and found incidentally; however, they carry a risk of rupture that can result in death from hemorrhage in the peritoneal cavity, retroperitoneal space, or gastrointestinal tract. Recent advances in imaging technology and its availability allow us to diagnose all types of VAA. VAAs can be treated by open surgery, laparoscopic surgery, endovascular therapy, or a hybrid approach. However, there are still no specific indications for the treatment of VAAs, and the best strategy depends on the anatomical location of the aneurysm as well as the clinical presentation of the patient. This article reviews the literature on the etiology, clinical features, diagnosis, and anatomic characteristics of each type of VAA and discusses the current options for their treatment and management.

Published
2019

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