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10 results on '"Mateus, J. C."'

1. Beyond a Transmission Cable--New Technologies to Reveal the Richness in Axonal Electrophysiology.

Author

Mateus, J. C., Sousa, M. M., Burrone, J., and Aguiar, P.

Abstract

The axon is a neuronal structure capable of processing, encoding, and transmitting information. This assessment contrasts with a limiting, but deeply rooted, perspective where the axon functions solely as a transmission cable of somatodendritic activity, sending signals in the form of stereotypical action potentials. This perspective arose, at least partially, because of the technical difficulties in probing axons: their extreme length-to-diameter ratio and intricate growth paths preclude the study of their dynamics through traditional techniques. Recent findings are challenging this view and revealing a much larger repertoire of axonal computations. Axons display complex signaling processes and structure-function relationships, which can be modulated via diverse activitydependent mechanisms. Additionally, axons can exhibit patterns of activity that are dramatically different from those of their corresponding soma. Not surprisingly, many of these recent discoveries have been driven by novel technology developments, which allow for in vitro axon electrophysiology with unprecedented spatiotemporal resolution and signal-to-noise ratio. In this review, we outline the state-of-the-art in vitro toolset for axonal electrophysiology and summarize the recent discoveries in axon function it has enabled. We also review the increasing repertoire of microtechnologies for controlling axon guidance which, in combination with the available cutting-edge electrophysiology and imaging approaches, have the potential for more controlled and high-throughput in vitro studies. We anticipate that a larger adoption of these new technologies by the neuroscience community will drive a new era of experimental opportunities in the study of axon physiology and consequently, neuronal function. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Evaluar la competencia mediática: una aproximación crítica desde las perspectivas pedagógica, política y metodológica.

Author

Mateus, J. C., Andrada, P., and Ferrés, J.

Subjects
*MASS media education, *EDUCATIONAL technology, *METHODOLOGY, *SELF-perception, *MASS media
Abstract

This article addresses the importance of developing an instrument that measures media competence, that is, the set of abilities to interact critically with the media. It introduces the problem of media education in the information society and argues the need to assess the skills of citizens in this context. It approaches this need from three perspectives: the pedagogical challenge that implies the little knowledge of the media competence and its little institutional formalization; the political discourse that privileges educational technology over media education; and the methodological question, analyzed from recent assessments of media competence applied in Spain, Chile and Peru, limited to the selfperception. Finally, we propose the construction of an instrument involving two features: integrative in terms of content, and innovative in terms of methodology. [ABSTRACT FROM AUTHOR]

Published
2019
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5. On the breeds of cattle-Historic and current classifications

Author

Felius, M., Koolmees, Peter A., Theunissen, B., Baumung, R., Manatrinon, S., Mommens, G., Holm, L. -E., Withen, K. B., Pedersen, B. V., Gravlund, P., Viinalass, H., Kantanen, J., Tapio, I., M. H., Li, Moazami-Goudarzi, K., Gautier, M., Denis, Laloë, Oulmouden, A., Levéziel, H., Taberlet, P., Harlizius, B., Simianer, H., Täubert, H., Erhardt, G., Jann, O., Weimann, C., Prinzenberg, E. -M., Medugorac, I., Medugorac, A., Förster, M., Mix, H. M., Looft, C., Kalm, E., Bradley, D. G., Edwards, C. J., Machugh, D. E., Freeman, A. R., Ajmone Marsan, P., Negrini, R., Longeri, M., Ceriotti, G., Zanotti, M., Marletta, D., Criscione, A., Valentini, A., Marchitelli, C., Pariset, L., Savarese, M. C., Pilla, F., Grislis, Z., Miceikienė, I., Nijman, I. J., van Haeringen, W., van de Goor, L., Olsaker, I., Ginja, C., Gama, L. T., Mateus, J. C., Beja-Pereira, A., Ferrand, N., Ivanova, Z., Popov, R., Ammosov, I., Kiselyova, T., Marzanov, N., Stojanovic, S., Simčič, M., Dovč, P., Kompan, D., Dunner, S., Rodellar, C., Martín-Burriel, I., Sánchez, A., Piedrafita, J., Azor, P. J., Delgado, J. V., Martínez-Martínez, A., Molina, A., Rodero, E., Dolf, G., Williams, J. L., Wiener, P., Bruford, M. W., Bray, T. C., Alderson, L., Penedo, M. C. T., Lenstra, J. A., Lenstra, Johannes A., Utrecht University [Utrecht], and European Cattle Genetic Diversity Consortium

Subjects
breeds, breed, [SDV]Life Sciences [q-bio], Ecology (disciplines), Breeds, Zoology, Ethnic origin, Subspecies, Q1, Crossbreed, 03 medical and health sciences, symbols.namesake, QH301, aurochs, auroch, lcsh:QH301-705.5, 030304 developmental biology, Nature and Landscape Conservation, 2. Zero hunger, 0303 health sciences, Genetic diversity, biology, Ecology, Ecological Modeling, Linnaean taxonomy, 0402 animal and dairy science, 04 agricultural and veterinary sciences, Aurochs, biology.organism_classification, cattle, classification, Classification, 040201 dairy & animal science, Agricultural and Biological Sciences (miscellaneous), Breed, Ecological Modelling, lcsh:Biology (General), Evolutionary biology, symbols, Cattle
Abstract

Chantier qualité GA Liste des auteurs de l'European Cattle Genetic Consortium, classés par pays : Austria: R. Baumung, S. Manatrinon, BOKU University, Vienna; Belgium: G. Mommens, University of Ghent, Merelbeke; Denmark: L.-E. Holm, Aarhus University, Tjele; K.B. Withen, B.V. Pedersen, P. Gravlund, University of Copenhagen, Copenhagen; Estonia: H. Viinalass, Estonian University of Life Sciences, Tartu; Finland: J. Kantanen, I. Tapio, M.H. Li, MTT, Jokioinen; France: K. Moazami-Goudarzi, M. Gautier, Denis Laloë, INRA, Jouy-en-Josas; A. Oulmouden, H. Levéziel, INRA, Limoges; P. Taberlet, Université Joseph Fourier et CNRS, Grenoble; Germany: B. Harlizius, School of Veterinary Medicine, Hannover; H. Simianer, H. Täubert, Georg-August-Universität, Göttingen; G. Erhardt, O. Jann, C. Weimann, E.-M. Prinzenberg, Justus-Liebig Universität, Giessen; I. Medugorac, A. Medugorac, M. Förster, Ludwig-Maximilians Universität, Munich; H.M. Mix, Naturschutz International, Grünheide; C. Looft, E. Kalm, Christian-Albrechts-Universität, Kiel; Ireland: D.G. Bradley, C.J. Edwards, D.E. MacHugh, A.R. Freeman, Trinity College, Dublin; Italy: P. Ajmone Marsan, R. Negrini, Università Cattolica del S. Cuore, Piacenza; M. Longeri, G. Ceriotti, M. Zanotti, Università degli Studi di Milano; D. Marletta, A. Criscione, Universita degli Studi di Catania, Catania; A. Valentini, C. Marchitelli, L. Pariset, M.C. Savarese, Università della Tuscia, Viterbo; F. Pilla, Università del Molise, Campobasso; Latvia: Z. Grislis, Latvia University of Agriculture, Jelgava; Lithuania: I. Miceikienė, Lithuanian Veterinary Academy, Kaunas; Netherlands: I.J. Nijman, Utrecht University; W. van Haeringen, L. van de Goor, Van Haeringen Laboratory, Wageningen; Norway: I. Olsaker, Norwegian School of Veterinary Science, Oslo; Portugal: C. Ginja, L.T.Gama, Instituto Nacional de Recursos Biológicos—INIA, Lisbon University, Lisboa; L.T. Gama, Instituto Nacional de Recursos Biológicos-INIA, I.P., Vale de Santarem; J.C. Mateus, Universidade de Trás-os-Montes e Alto Douro, Vila Real; A. Beja-Pereira, N. Ferrand, Oporto University; Russia: Z. Ivanova, R. Popov, I. Ammosov, Yakutian Research Institute of Agricultural Sciences, Yakutsk, Sakha; T. Kiselyova, All-Russian Research Institute for Farm Animals and Breeding, St. Petersburgh-Pushkin; N. Marzanov, All-Russian Research Institute of Animal Husbandry, Dubrovitsy; Serbia: S. Stojanovic, Ministry of Agriculture and Water Management, Belgrade; Slovenia: M. Simčič, P. Dovč, D.Kompan, University of Ljubljana, Domzale; Spain: S. Dunner, Universidad Complutense de Madrid; C. Rodellar, I. Martín-Burriel, Veterinary Faculty, Zaragoza; A. Sánchez, J. Piedrafita, Universitat Autònoma de Barcelona; P.J. Azor, J.V. Delgado, A. Martínez-Martínez, A. Molina, E. Rodero, University of Córdoba; Switzerland: G. Dolf, University of Berne; UK: J.L. Williams, P. Wiener, Roslin Institute; M.W. Bruford, T.C. Bray, Cardiff University, Cardiff; L. Alderson, Countrywide Livestock Ltd, Shrewsbury; USA: M.C.T. Penedo. University of California, Davis, CA; International audience; Classification of cattle breeds contributes to our understanding of the history of cattle and is essential for an effective conservation of genetic diversity. Here we review the various classifications over the last two centuries and compare the most recent classifications with genetic data. The classifications devised during the 19th to the late 20th century were in line with the Linnaean taxonomy and emphasized cranial or horn morphology. Subsequent classifications were based on coat color, geographic origin or molecular markers. Several theories were developed that linked breed characteristics either to a supposed ancestral aurochs subspecies or to a presumed ethnic origin. Most of the older classifications have now been discarded, but have introduced several Latin terms that are still in use. The most consistent classification was proposed in 1995 by Felius and emphasizes the geographic origin of breeds. This is largely in agreement with the breed clusters indicated by a biochemical and molecular genetic analysis, which reflect either groups of breeds with a common geographic origin or single breeds that have expanded by export and/or crossbreeding. We propose that this information is also relevant for managing the genetic diversity of cattle.

Published
2011
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10. Bidirectional flow of action potentials in axons drives activity dynamics in neuronal cultures.

Author

Mateus JC, Lopes C, Aroso M, Costa AR, Gerós A, Meneses J, Faria P, Neto E, Lamghari M, Sousa MM, and Aguiar P

Subjects
Action Potentials physiology, Ganglia, Spinal, Synapses physiology, Axons physiology, Neurons
Abstract

Objective . Recent technological advances are revealing the complex physiology of the axon and challenging long-standing assumptions. Namely, while most action potential (AP) initiation occurs at the axon initial segment in central nervous system neurons, initiation in distal parts of the axon has been reported to occur in both physiological and pathological conditions. The functional role of these ectopic APs, if exists, is still not clear, nor its impact on network activity dynamics. Approach . Using an electrophysiology platform specifically designed for assessing axonal conduction we show here for the first time regular and effective bidirectional axonal conduction in hippocampal and dorsal root ganglia cultures. We investigate and characterize this bidirectional propagation both in physiological conditions and after distal axotomy. Main results. A significant fraction of APs are not coming from the canonical synapse-dendrite-soma signal flow, but instead from signals originating at the distal axon. Importantly, antidromic APs may carry information and can have a functional impact on the neuron, as they consistently depolarize the soma. Thus, plasticity or gene transduction mechanisms triggered by soma depolarization can also be affected by these antidromic APs. Conduction velocity is asymmetrical, with antidromic conduction being slower than orthodromic. Significance. Altogether these findings have important implications for the study of neuronal function in vitro , reshaping our understanding on how information flows in neuronal cultures., (© 2021 IOP Publishing Ltd.)

Published
2021
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