376 results on '"Matera, G."'
Search Results
2. Efficacy of cefiderocol- vs colistin-containing regimen for treatment of bacteraemic ventilator-associated pneumonia caused by carbapenem-resistant Acinetobacter baumannii in patients with COVID-19
- Author
-
Russo, A., Bruni, A., Gullì, S., Borrazzo, C., Quirino, A., Lionello, R., Serapide, F., Garofalo, E., Serraino, R., Romeo, F., Marascio, N., Matera, G., Longhini, F., Trecarichi, E.M., and Torti, C.
- Published
- 2023
- Full Text
- View/download PDF
3. Seroprevalence of torch infections in childbearing age women: 2019-2022 time span results from a teaching hospital in Southern Italy
- Author
-
Pavia, G., primary, De Angelis, G., additional, Giancotti, A., additional, Zangari, C., additional, Laratta, E., additional, Colosimo, E., additional, Mancuso, E., additional, Prestagiacomo, L., additional, Mirello, C., additional, Gigliotti, S., additional, Licata, F., additional, Angelillo, S., additional, Trecarichi, E. M., additional, Costa, C., additional, Torti, C., additional, Marascio, N., additional, Quirino, A., additional, and Matera, G., additional
- Published
- 2023
- Full Text
- View/download PDF
4. The intrinsic complexity of parametric elimination methods
- Author
-
Heintz, J., Matera, G., Pardo, L. M., and Wachenchauzer, R.
- Subjects
Mathematics - Algebraic Geometry - Abstract
This paper is devoted to the complexity analysis of a particular property, called "algebraic robustness" owned by all known symbolic methods of parametric polynomial equation solving (geometric elimination). It is shown that any parametric elimination procedure which owns this property must neccessarily have an exponential sequential time complexity., Comment: LaTeX, 12 pages. To appear in Proc. of WAIT'97, Buenos Aires, Argentina, 1997
- Published
- 1997
5. Nutrigenomics: SNPs correlated to Food Preferences and Susceptibilities.
- Author
-
Medori, M. C., Dhuli, K., Bonetti, G., Donato, K., Cristoni, S., Ceccarini, M. R., Beccari, T., Iaconelli, A., Aquilanti, B., Matera, G., Herbst, K. L., Connelly, S. T., and Bertelli, M.
- Subjects
NUTRITIONAL genomics ,PHYSICAL activity ,SINGLE nucleotide polymorphisms ,HEALTH outcome assessment ,PHYSICAL fitness ,FOOD preferences - Abstract
Background. Nutrigenomics explores the intricate interplay between single nucleotide polymorphisms (SNPs), food preferences, and susceptibilities. Methods. This study delves into the influence of SNPs on food sensitivities, allergies, tyramine intolerance, and taste preferences. Genetic factors intricately shape physiological reactions to dietary elements, with polymorphisms contributing to diverse sensitivities and immune responses. Results. Tyramine intolerance, arising from metabolic inefficiencies, unveils genetic markers exerting influence on enzyme function. SNPs transcend genetic diversity by exerting substantial impact on food sensitivities/allergies, with specific variants correlating to heightened susceptibilities. Genes accountable for digesting food components play pivotal roles. Given the rising prevalence of food sensitivities/allergies, understanding genetic foundations becomes paramount. In the realm of taste and food preferences, SNPs sculpt perception and choice, yielding variances in taste perception and preferences for sweetness, bitterness, and umami. This genetic medley extends its reach to encompass wider health implications. Conclusions. In this review article, we have focused on how polymorphisms wield significant sway over physiological responses, sensitivities, and dietary inclinations. Unraveling these intricate relationships illuminates the path to personalized nutrition, potentially revolutionizing tailored recommendations and interventions. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
6. Nutrigenomics: SNPs correlated to detoxification, antioxidant capacity and longevity.
- Author
-
Bonetti, G., Medori, M. C., Dhuli, K., Macchia, A., Donato, K., Cristoni, S., Miertus, S., Miertus, J., Veselenyiova, D., Iaconelli, A., Aquilanti, B., Matera, G., Connelly, S. T., and Bertelli, M.
- Subjects
SINGLE nucleotide polymorphisms ,PHYSICAL activity ,HEALTH outcome assessment ,PHYSICAL fitness ,DETOXIFICATION (Alternative medicine) - Abstract
Nutritional genomics, also known as nutrigenomics, is the study of how a person's diet and genes interact with each other. The field of nutrigenomics aims to explain how common nutrients, food additives and preservatives can change the body's genetic balance towards either health or sickness. This study reviews the effects of SNPs on detoxification, antioxidant capacity, and longevity. SNPs are mutations that only change one nucleotide at a specific site in the DNA. Specific SNPs have been associated to a variety of biological processes, including detoxification, antioxidant capacity, and longevity. This article mainly focuses on the following genes: SOD2, AS3MT, CYP1A2, and ADORA2A (detoxification); LEPR, TCF7L2, KCNJ11, AMY1, and UCP3 (antioxidant capacity); FOXO3 and BPIFB4 (longevity). This review underlines that many genes--among which FOXO3, TCF7L2, LEPR, CYP1A2, ADORA2A, and SOD2--have a unique effect on a person's health, susceptibility to disease, and general well-being. Due to their important roles in numerous biological processes and their implications for health, these genes have undergone intensive research. Examining the SNPs in these genes can provide insight into how genetic variants affect individuals' responses to their environment, their likelihood of developing certain diseases, and their general state of health. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
7. Nutrigenomics: SNPs Correlated to Lipid and Carbohydrate Metabolism.
- Author
-
Madeo, G., Donato, K., Micheletti, C., Cristoni, S., Miertus, S., Miertus, J., Veselenyiova, D., Iaconelli, A., Aquilanti, B., Matera, G., Connelly, S. Thaddeus, and Bertelli, M.
- Subjects
SINGLE nucleotide polymorphisms ,PHYSICAL activity ,HEALTH outcome assessment ,PHYSICAL fitness ,MEDICAL care ,CARBOHYDRATE metabolism - Abstract
Background. Nutrigenomics - the study of the interactions between genetics and nutrition - has emerged as a pivotal field in personalized nutrition. Among various genetic variations, single-nucleotide polymorphisms (SNPs) have been extensively studied for their probable relationship with metabolic traits. Methods. Throughout this review, we have employed a targeted research approach, carefully handpicking the most representative and relevant articles on the subject. Our methodology involved a systematic review of the scientific literature to ensure a comprehensive and accurate overview of the available sources. Results. SNPs have demonstrated a significant influence on lipid metabolism, by impacting genes that encode for enzymes involved in lipid synthesis, transport, and storage. Furthermore, they have the ability to affect enzymes in glycolysis and insulin signaling pathways: in a way, they can influence the risk of type 2 diabetes. Thanks to recent advances in genotyping technologies, we now know numerous SNPs linked to lipid and carbohydrate metabolism. The large-scale studies on this topic have unveiled the potential of personalized dietary recommendations based on an individual's genetic makeup. Personalized nutritional interventions hold promise to mitigate the risk of various chronic diseases; however, translating these scientific insights into actionable dietary guidelines is still challenging. Conclusions. As the field of nutrigenomics continues to evolve, collaborations between geneticists, nutritionists, and healthcare providers are essential to harness the power of genetic information for improving metabolic health. By unraveling the genetic basis of metabolic responses to diet, this field holds the potential to revolutionize how we approach dietary recommendations and preventive healthcare practices. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
8. Nutrigenomics: SNPs correlated to minerals' deficiencies.
- Author
-
Dhuli, K., Medori, M. C., Bonetti, G., Donato, K., Cristoni, S., Miertus, S., Miertus, J., Veselenyiova, D., Iaconelli, A., Aquilanti, B., Matera, G., Connelly, S. T., and Bertelli, M.
- Subjects
SINGLE nucleotide polymorphisms ,HEALTH outcome assessment ,PHYSICAL activity ,PHYSICAL fitness ,MEDICAL care - Abstract
Nutrigenetics and nutrigenomics are two interrelated fields that explore the influence of genetic diversity on nutrient responses and function. While nutrigenetics investigates the effects of hereditary genetic variations on micronutrient metabolism, nutrigenomics examines the intricate relationship between diet and the genome, studying how genetic variants impact nutrient intake and gene expression. These disciplines offer valuable insights into predicting and managing chronic diseases through personalized nutritional approaches. Nutrigenomics employs cutting-edge genomics technologies to study nutrient-genome interactions. Key principles involve genetic variability among ethnic groups, affecting nutrient bioavailability and metabolism, and the influence of dietary choices based on cultural, geographic, and socioeconomic factors. Polymorphisms, particularly single-nucleotide polymorphisms (SNPs), significantly influence gene activity and are associated with specific phenotypes that are related to micronutrient deficiencies. Minerals are inorganic elements, vital for various physiological functions. Understanding the SNPs associated with mineral deficiencies is crucial for assessing disease risk and developing personalized treatment plans. This knowledge can inform public health interventions, targeted screening programs, educational campaigns, and fortified food products to address deficiencies effectively. Nutrigenomics research has the potential to revolutionize clinical and nutritional practices, providing personalized recommendations, enhancing illness risk assessment, and advancing public health initiatives. Despite the need for further research, harnessing nutrigenomics' potential can lead to more focused and efficient methods for preventing and treating mineral deficiencies. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
9. Nutrigenomics: SNPs correlated to physical activity, response to chiropractic treatment, mood and sleep.
- Author
-
Donato, K., Madeo, G., Micheletti, C., Cristoni, S., Ceccarini, M. R., Beccari, T., Iaconelli, A., Aquilanti, B., Matera, G., Herbst, K. L., and Bertelli, M.
- Subjects
SINGLE nucleotide polymorphisms ,HEALTH outcome assessment ,PHYSICAL activity ,PHYSICAL fitness ,MEDICAL care - Abstract
Nutrigenomics, a rapidly evolving field that bridges genetics and nutrition, explores the intricate interactions between an individual's genetic makeup and how they respond to nutrients. At its core, this discipline focuses on investigating Single Nucleotide Polymorphisms (SNPs), the most common genetic variations, which significantly influence a person's physiological status, mood regulation, and sleep patterns, thus playing a pivotal role in a wide range of health outcomes. Through decoding their functional implications, researchers are able to uncover genetic factors that impact physical fitness, pain perception, and susceptibility to mood disorders and sleep disruptions. The integration of nutrigenomics into healthcare holds the promise of transformative interventions that cater to individual well-being. Notable studies shed light on the connection between SNPs and personalized responses to exercise, as well as vulnerability to mood disorders and sleep disturbances. Understanding the intricate interplay between genetics and nutrition informs targeted dietary approaches, molding individual health trajectories. As research advances, the convergence of genetics and nourishment is on the brink of reshaping healthcare, ushering in an era of personalized health management that enhances overall life quality. Nutrigenomics charts a path toward tailored nutritional strategies, fundamentally reshaping our approach to health preservation and preventive measures. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
10. Nutrigenomics: SNPs correlated to vitamins' deficiencies.
- Author
-
Micheletti, C., Madeo, G., Macchia, A., Donato, K., Cristoni, S., Ceccarini, M. R., Beccari, T., Iaconelli, A., Aquilanti, B., Matera, G., Herbst, K. L., and Bertelli, M.
- Subjects
SINGLE nucleotide polymorphisms ,NUTRITIONAL genomics ,HEALTH outcome assessment ,COVID-19 pandemic ,PUBLIC health - Abstract
Nutrients can influence the physiological processes in the body by interacting with molecular systems. Including nutrigenetics and nutrigenomics, nutritional genomics focuses on how bio-active food components interact with the genome. The purpose of this study is to clarify how nutrigenomics and vitamin dietary deficits relate to one another. Food tolerances among human sub-populations are known to vary due to genetic variation, which may also affect dietary needs. This raises the prospect of tailoring a person's nutritional intake for optimum health and illness prevention, based on their unique genome. To better understand the interplay between genes and nutrients and to plan tailored weight loss, nutrigenetic testing may soon become a key approach. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
11. Effects of Carob Extract on the Intestinal Microbiome and Glucose Metabolism: A Systematic Review and Meta-Analysis.
- Author
-
Micheletti, C., Medori, M. C., Bonetti, G., Iaconelli, A., Aquilanti, B., Matera, G., and Bertelli, M.
- Subjects
GUT microbiome ,COVID-19 pandemic ,HEALTH outcome assessment ,POLYPHENOLS ,PUBLIC health - Abstract
The legume tree known as carob (Ceratonia siliqua L.) is indigenous to the Mediterranean area and over the centuries its pods had been traditionally used mostly as animal feed. However, it has gained great attention in human nutrition due to the molecular compounds it contains, which could offer many potential health benefits: for example, carob is renowned for its high content of fiber, vitamins, and minerals. Moreover, in traditional medicine it is credited with the ability to control glucose metabolism and gut microbiome. Modern science has also extensively acknowledged the numerous health advantages deriving from its consumption, including its anti-diabetic, anti-inflammatory, and antioxidant properties. Due to its abundant contents of pectin, gums, and polyphenols (such as pinitol), carob has garnered significant attention as a well-researched plant with remarkable therapeutic properties. Notably, carob is extensively used in the production of semi-finished pastry products, particularly in ice cream and other creams (especially as a substitute for cocoa/chocolate): these applications indeed facilitate the exploration of its positive effects on glucose metabolism. Our study aimed at examining the effects of carob extract on intestinal microbiota and glucose metabolism. In this review, we conducted a thorough examination, comprising in vitro, in vivo, and clinical trials to appraise the consequences on human health of polyphenols and pectin from different carob species, including recently discovered ones with high polyphenol contents. Our goal was to learn more about the mechanisms through which carob extract can support a balanced gut flora and improve one's glucose metabolism. These results could influence the creation of novel functional foods and dietary supplements, to help with the management and prevention of chronic illnesses like diabetes and obesity. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
12. Olive tree polyphenols as effective and sustainable grain preservatives.
- Author
-
Donato, K., Dhuli, K., Madeo, G., Iaconelli, A., Aquilanti, B., Matera, G., Beccari, T., Ceccarini, M. R., and Bertelli, M.
- Subjects
HEALTH outcome assessment ,COVID-19 pandemic ,POLYPHENOLS ,GRAIN trade ,CHEMICALS - Abstract
Whole grains play a crucial role in the human diet. Despite being cultivated in distinct regions, they are shipped everywhere, therefore making biosafety and security essential throughout the grain industry, from harvest to distribution. Phytopathogens, which have an impact on crop yield, induce grain spoiling and reduce grain quality in a number of ways, providing a constant danger to crop storage and distribution. Chemical control approaches, such as the use of pesticides and fungicides, are detrimental to the environment and hazardous to human health. The development of alternative, environmentally friendly, and generally acceptable solutions to ensure increased grain yield, biosafety, and quality during storage is crucial in order to guarantee sufficient food and feed supplies. As a means of self-defense against microbial infection and spoilage, plant matrices feature antimicrobial natural chemicals, which have led to their widespread usage as food preservatives in recent decades. Olive tree extracts, known for their high polyphenol content, have been widely used in the food preservation industry with great success, and are highly welcomed by people all over the world. In addition to their well-known health advantages, polyphenols are a valuable plant secondary metabolite because of their great antibacterial capabilities as natural preservatives. This article discusses the promising usage of polyphenols from olive trees as a natural alternative preservative, while also highlighting the future of olive eaves in the food industry. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
13. Omics sciences and precision medicine in pancreas cancer.
- Author
-
Donato, K., Micheletti, C., Medori, M. C., Maltese, P. E., Tanzi, B., Tezzele, S., Mareso, C., Generali, D., Donofrio, C. A., Cominetti, M., Fioravanti, A., Riccio, L., Beccari, T., Ceccarini, M. R., Iaconelli, A., Aquilanti, B., Matera, G., Ahmed, R., Stuppia, L., and Gatta, V.
- Subjects
INDIVIDUALIZED medicine ,PANCREAS ,METABOLOMICS ,METABOLITES ,BIOMARKERS ,HEALTH outcome assessment - Abstract
Pancreatic cancer is a leading cause of death worldwide, associated with poor prognosis outcomes and late treatment interventions. The pathological nature and extreme tissue heterogeneity of this disease has hampered all efforts to correctly diagnose and treat it. Omics sciences and precision medicine have revolutionized our understanding of pancreatic cancer, providing a new hope for patients suffering from this devastating disease. By analyzing large-scale biological data sets and developing personalized treatment strategies, researchers and clinicians are working together to improve patient outcomes and ultimately find a cure for pancreatic cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
14. Omics sciences and precision medicine in colon cancer.
- Author
-
Madeo, G., Bonetti, G., Gadler, M., Benedetti, S., Guerri, G., Cristofoli, F., Generali, D., Donofrio, C. A., Cominetti, M., Fioravanti, A., Riccio, L., Bernini, A., Fulcheri, E., Iaconelli, A., Aquilanti, B., Matera, G., Stuppia, L., Gatta, V., Cecchin, S., and Marceddu, G.
- Subjects
INDIVIDUALIZED medicine ,COLON cancer ,HEALTH outcome assessment ,METABOLOMICS ,METABOLITES ,BIOMARKERS - Abstract
Colon cancer presents a complex pathophysiological landscape, which poses a significant challenge to the precise prediction of patient prognosis and treatment response. However, the emergence of omics sciences such as genomics, transcriptomics, proteomics, and metabolomics has provided powerful tools to identify molecular alterations and pathways involved in colon cancer development and progression. To address the lack of literature exploring the intersection of omics sciences, precision medicine, and colon cancer, we conducted a comprehensive search in ScienceDirect and PubMed databases. We included systematic reviews, reviews, case studies, clinical studies, and randomized controlled trials that were published between 2015-2023. To refine our search, we excluded abstracts and non-English studies. This review provides a comprehensive summary of the current understanding of the latest developments in precision medicine and omics sciences in the context of colon cancer. Studies have identified molecular subtypes of colon cancer based on genomic and transcriptomic profiles, which have implications for prognosis and treatment selection. Furthermore, precision medicine (which involves tailoring treatments, based on the unique molecular characteristics of each patient's tumor) has shown promise in improving outcomes for colon cancer patients. Omics sciences and precision medicine hold great promise for identifying new therapeutic targets and developing more effective treatments for colon cancer. Although not strictly designed as a systematic review, this review provides a readily accessible and up-to-date summary of the latest developments in the field, highlighting the challenges and opportunities for future research. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
15. Severe myocarditis due to influenza A(H1N1)pdm09 viral infection in a young woman successfully treated with intravenous zanamivir: A case report
- Author
-
Mazzitelli, M., Garofalo, E., Bruni, A., Barreca, G. S., Quirino, A., Giancotti, A., Serapide, F., Indolfi, C., Matera, G., Navalesi, P., Trecarichi, E. M., Torti, C., Longhini, F., Peronace, C., Pisani, V., Costa, C., Greco, G., La Gamba, V., Scaglione, V., Biamonte, E., Brescia, V., De Leonardis, B., Karim, A., Cimino, G., La Torre, P., Gemelli, A., Tropea, F. A., Picicco, F., and Gallo, L.
- Subjects
Drug ,intravenous zanamivir ,medicine.medical_specialty ,Oseltamivir ,Myocarditis ,viruses ,media_common.quotation_subject ,lcsh:Medicine ,Case Report ,Case Reports ,030204 cardiovascular system & hematology ,Viral infection ,Gastroenterology ,influenza A(H1N1)pdm09 virus ,Intestinal malabsorption ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Zanamivir ,Internal medicine ,myocarditis ,medicine ,In patient ,media_common ,lcsh:R5-920 ,business.industry ,lcsh:R ,food and beverages ,virus diseases ,Influenza a ,General Medicine ,biochemical phenomena, metabolism, and nutrition ,medicine.disease ,respiratory tract diseases ,chemistry ,030220 oncology & carcinogenesis ,lcsh:Medicine (General) ,business ,medicine.drug - Abstract
In patients with influenza‐related myocarditis, prompt diagnosis and treatment are important. Intravenous zanamivir can be an alternative to oral oseltamivir, especially in severe cases and when drug intestinal malabsorption is suspected or proven.
- Published
- 2019
16. Direct antimicrobial susceptibility testing (AST) from positive blood cultures using Microscan system for early detection of bacterial resistance phenotypes
- Author
-
Quirino, A., Marascio, N., Peronace, C., Gallo, L., Barreca, G.S., Giancotti, A., Lamberti, A.G., Colosimo, M., Minchella, P., Trecarichi, E.M., Torti, C., Liberto, M.C., and Matera, G.
- Published
- 2021
- Full Text
- View/download PDF
17. OC-11Development of NAFLD/NASH multidisciplinary board: MetaLiverCat experience
- Author
-
Miele, L., primary, Ponziani, F.R., additional, Liguori, A., additional, Nicoletti, A., additional, Fianchi, F., additional, Santopaolo, F., additional, Nesci, A., additional, De Leva, F., additional, Marini, M.G., additional, Aquilanti, B., additional, Matera, G., additional, Casa, S. Della, additional, De Magistris, A., additional, Gagliardi, L., additional, Marrone, G., additional, Biolato, M., additional, Pizzolante, F., additional, De Matthaeis, N., additional, Salvatore, L., additional, Guidone, C., additional, Zocco, M.A., additional, Pitocco, D., additional, De Gaetano, A.M., additional, De Simone, C., additional, Santoloquido, A., additional, Mingrone, G., additional, Raffaelli, M., additional, Miggiano, G.A., additional, Manfredi, R., additional, Vecchio, F.M., additional, Giaccari, A., additional, Pompili, M., additional, Grieco, A., additional, and Gasbarrini, A., additional
- Published
- 2021
- Full Text
- View/download PDF
18. CYP26B1 and its implications in lymphangiogenesis: Literature review and study of rare variants in two families
- Author
-
Ricci, M., Serrani, R., Amato, B., Compagna, R., Veselenyiova, D., Kenanoglu, S., Kurti, D., Baglivo, M., Krajcovic, J., Miggiano, G. A. D., Aquilanti, B., Matera, G., Velluti, V., Gagliardi, L., Munis Dundar, Basha, S. H., Bertelli, M., Ricci, M, Serrani, R, Amato, B, Compagna, R, Veselenyiova, D, Kenanoglu, S, Kurti, D, Baglivo, M, Krajcovic, J, Miggiano, G A D, Aquilanti, B, Matera, G, Velluti, V, Gagliardi, L, Dundar, M, Basha, S H, and Bertelli, M
- Subjects
CYP26B1 (Cytochrome P450 Family 26 Subfamily B Member 1) ,NGS (Next Generation Sequencing) ,retinoic acid ,Immunology and Allergy ,lymphangiogenesi ,Hematology ,lymphedema ,genetic diagnosi ,lymphvascular genomic - Abstract
CYP26B1 is a member of the cytochrome P450 family and is responsible for the breakdown of retinoic acid for which appropriate levels are important for normal development of the cardiovascular and lymphatic systems. In a cohort of 235 patients with lymphatic malformations, we performed genetic testing for the CYP26B1 gene. These probands had previously tested negative for known lymphedema genes. We identified two heterozygous missense CYP26B1 variants in two patients. Our bioinformatic study suggested that alterations caused by these variants have no major effect on the overall stability of CYP26B1 protein structure. Balanced levels of retinoic acid maintained by CYP26B1 are crucial for the lymphatic system. We identified that CYP26B1 could be involved in predisposition for lymphedema. We propose that CYP26B1 be further explored as a new candidate gene for genetic testing of lymphedema patients.
- Published
- 2020
19. RARE PECAM1 VARIANTS IN THREE FAMILIES WITH LYMPHEDEMA
- Author
-
Michelini, S, primary, Amato, B, additional, Kenanoglu, S, additional, Veselenyiova, D, additional, Dautaj, A, additional, Kurti, D, additional, Baglivo, M, additional, Dundar, M, additional, Krajcovic, J, additional, Miggiano, GAD, additional, Aquilanti, B, additional, Matera, G, additional, Velluti, V, additional, Gagliardi, L, additional, Basha, SH, additional, and Bertelli, M, additional
- Published
- 2021
- Full Text
- View/download PDF
20. Epidemiological features and specificities of HCV infection: a hospital-based cohort study in a university medical center of Calabria region
- Author
-
Liberto MC, Marascio N, Zicca E, and Matera G
- Subjects
Infectious and parasitic diseases ,RC109-216 - Abstract
Abstract The epidemiological status of HCV in Europe, and in particular in Mediterranean countries, is continuously evolving. The genotype distribution is related to improvement of healthcare conditions, expansion of intravenous drug use and immigration. We review and characterize the epidemiology of the distribution of HCV genotypes within Calabria, an area of Southern Italy. We focus on the pattern of distinct HCV genotype changes over the last 16 years; particularly subtype 1b and genotype 4. We collected data by evaluating a hospital-based cohort of chronic hepatitis C patients; in addition, we report an update including new patients enrolled during last eight months.
- Published
- 2012
- Full Text
- View/download PDF
21. RARE PECAM1 VARIANTS IN THREE FAMILIES WITH LYMPHEDEMA
- Author
-
Michelini, S., Amato, B., Kenanoglu, S., Veselenyiova, D., Dautaj, A., Kurti, D., Baglivo, M., Munis Dundar, Krajcovic, J., Miggiano, G. A., Aquilanti, B., Matera, G., Velluti, V., Gagliardi, L., Basha, S. H., and Bertelli, M.
- Subjects
Immunology and Allergy ,Hematology ,humanities - Abstract
PECAM1 is a member of the immunoglobulin superfamily and is expressed in monocytes, neutrophils, macrophages and other types of immune cells as well as in endothelial cells. PECAM1 function is crucial for the development and maturation of B lymphocytes. The aim of this study was to link rare PECAM1 variants found in lymphedema patients with the development of lymphatic system malformations. Using NGS, we previously tested 246 Italian lymphedema patients for variants in 29 lymphedema-associated genes and obtained 235 negative results. We then tested these patients for variants in the PECAM1 gene. We found three probands with rare variants in PECAM1. All variants were heterozygous missense variants. In Family 1, the unaffected mother and brother of the proband were found to carry the same variant as the proband. Lymphoscintigraphy was performed to determine possible lymphatic malformations and showed that in both cases a bilateral slight reduction in the speed and lymphatic clearance of the lower limbs. PECAM1 function is important for lymphatic vasculature formation. We found variants in PECAM1 that may be associated with susceptibility to lymphedema.
- Published
- 2020
22. The Hardness of Polynomial Equation Solving
- Author
-
Castro, D., Giusti, M., Heintz, J., Matera, G., and Pardo, L.M.
- Published
- 2003
- Full Text
- View/download PDF
23. Cytokine milieu and nitrite release during early challenge of human PBMC by Leishmania infantum and Leishmania major: P010
- Author
-
Matera, G., Quirino, A., Rametti, L., Arvaniti, M., Liberto, M. C., and Focà, A.
- Published
- 2012
- Full Text
- View/download PDF
24. CYP26B1 AND ITS IMPLICATIONS IN LYMPHANGIOGENESIS: LITERATURE REVIEW AND STUDY OF RARE VARIANTS IN TWO FAMILIES
- Author
-
Ricci, M, primary, Serrani, R, additional, Amato, B, additional, Compagna, R, additional, Veselenyiova, D, additional, Kenanoglu, S, additional, Kurti, D, additional, Baglivo, M, additional, Krajcovic, J, additional, Miggiano, GAD, additional, Aquilanti, B, additional, Matera, G, additional, Velluti, V, additional, Gagliardi, L, additional, Dundar, M, additional, Basha, SH, additional, and Bertelli, M, additional
- Published
- 2020
- Full Text
- View/download PDF
25. Dietary Patterns and Mortality in a Multinational Cohort of Adults Receiving Hemodialysis
- Author
-
Saglimbene, Valeria M., primary, Wong, Germaine, additional, Teixeira-Pinto, Armando, additional, Ruospo, Marinella, additional, Garcia-Larsen, Vanessa, additional, Palmer, Suetonia C., additional, Natale, Patrizia, additional, Campbell, Katrina, additional, Carrero, Juan-Jesus, additional, Stenvinkel, Peter, additional, Gargano, Letizia, additional, Murgo, Angelo M., additional, Johnson, David W., additional, Tonelli, Marcello, additional, Gelfman, Rubén, additional, Celia, Eduardo, additional, Ecder, Tevfik, additional, Bernat, Amparo G., additional, Del Castillo, Domingo, additional, Timofte, Delia, additional, Török, Marietta, additional, Bednarek-Skublewska, Anna, additional, Duława, Jan, additional, Stroumza, Paul, additional, Hansis, Martin, additional, Fabricius, Elisabeth, additional, Felaco, Paolo, additional, Wollheim, Charlotta, additional, Hegbrant, Jörgen, additional, Craig, Jonathan C., additional, Strippoli, Giovanni F.M., additional, Badino, A., additional, Petracci, L., additional, Villareal, C., additional, Soto, M., additional, Arias, M., additional, Vera, F., additional, Quispe, V., additional, Morales, S., additional, Bueno, D., additional, Bargna, R., additional, Peñaloza, G., additional, Alcalde, L., additional, Dayer, J., additional, Milán, A., additional, Centurión, N., additional, Ramos, A., additional, De Orta, E., additional, Menardi, S., additional, Austa Bel, N., additional, Marileo, E., additional, Junqueras, N., additional, Favalli, C., additional, Trioni, R., additional, Valle, G., additional, López, M., additional, Marinaro, C., additional, Fernandez, A., additional, Corral, J., additional, Nattiello, E., additional, Marone, S., additional, García, J., additional, Carrizo, G., additional, González, P., additional, Delicia, O., additional, Maza, M., additional, Chauque, M., additional, Mora, J., additional, Grbavac, D., additional, López, L., additional, Alonso, M., additional, Villalba, C., additional, Simon, M., additional, Cernadas, M., additional, Moscatelli, C., additional, Vilamajó, I., additional, Tursky, C., additional, Martínez, M., additional, Villalba, F., additional, Pereira, D., additional, Araujo, S., additional, López, H., additional, Alonso, V., additional, Vázquez, B., additional, Rapetti, M., additional, Raña, S., additional, Capdevila, M., additional, Ljubich, C., additional, Acosta, M., additional, Coombes, M., additional, Doria, V., additional, Ávila, M., additional, Cáceres, D., additional, Geandet, E., additional, Romero, C., additional, Morales, E., additional, Recalde, C., additional, Casanú, M., additional, Lococo, B., additional, Da Cruz, O., additional, Focsaner, C., additional, Galarce, D., additional, Albarracín, L., additional, Vescovo, E., additional, Gravielle, M., additional, Florio, D., additional, Baumgart, L., additional, Corbalán, M., additional, Aguilera, V., additional, Hermida, O., additional, Galli, C., additional, Ziombra, L., additional, Gutierrez, A., additional, Frydelund, S., additional, Hardaman, A., additional, Maciel, A., additional, Arrigo, M., additional, Mato Mira, C., additional, Leibovich, J., additional, Paparone, R., additional, Muller, E., additional, Malimar, A., additional, Leocadio, I., additional, Cruz, W., additional, Tirado, S., additional, Peñalba, A., additional, Cejas, R., additional, Mansilla, S., additional, Campos, C., additional, Abrego, E., additional, Chávez, P., additional, Corpacci, G., additional, Echavarría, A., additional, Engler, C., additional, Vergara, P., additional, Hubeli, M., additional, Redondo, G., additional, Noroña, B., additional, Boriceanu, C., additional, Lankester, M., additional, Poignet, J.L., additional, Saingra, Y., additional, Indreies, M., additional, Santini, J., additional, Mahi, A., additional, Robert, A., additional, Bouvier, P., additional, Merzouk, T., additional, Villemain, F., additional, Pajot, A., additional, Tollis, F., additional, Brahim-Bounab, M., additional, Benmoussa, A., additional, Albitar, S., additional, Guimont, M.C., additional, Ciobotaru, P., additional, Guerin, A., additional, Diaconita, M., additional, Hoischen, S.H., additional, Saupe, J., additional, Ullmann, I., additional, Grosser, S., additional, Kunow, J., additional, Grueger, S., additional, Bischoff, D., additional, Benders, J., additional, Worch, P., additional, Pfab, T., additional, Kamin, N., additional, Roesch, M., additional, May, M., additional, Albert, K., additional, Csaszar, I., additional, Kiss, E., additional, Kosa, D., additional, Orosz, A., additional, Redl, J., additional, Kovacs, L., additional, Varga, E., additional, Szabo, M., additional, Magyar, K., additional, Zajko, E., additional, Bereczki, A., additional, Csikos, J., additional, Kerekes, E., additional, Mike, A., additional, Steiner, K., additional, Nemeth, E., additional, Tolnai, K., additional, Toth, A., additional, Vinczene, J., additional, Szummer, S.z., additional, Tanyi, E., additional, Szilvia, M., additional, Murgo, A.M., additional, Sanfilippo, N., additional, Dambrosio, N., additional, Saturno, C., additional, Matera, G., additional, Benevento, M., additional, Greco, V., additional, di Leo, G., additional, Papagni, S., additional, Alicino, F., additional, Marangelli, A., additional, Pedone, F., additional, Cagnazzo, A.V., additional, Antinoro, R., additional, Sambati, M.L., additional, Donatelli, C., additional, Ranieri, F., additional, Torsello, F., additional, Steri, P., additional, Riccardi, C., additional, Flammini, A., additional, Moscardelli, L., additional, Boccia, E., additional, Mantuano, M., additional, Di Toro Mammarella, R., additional, Meconizzi, M., additional, Fichera, R., additional, D’Angelo, A., additional, Latassa, G., additional, Molino, A., additional, Fici, M., additional, Lupo, A., additional, Montalto, G., additional, Messina, S., additional, Capostagno, C., additional, Randazzo, G., additional, Pagano, S., additional, Marino, G., additional, Rallo, D., additional, Maniscalco, A., additional, Trovato, O.M., additional, Strano, C., additional, Failla, A., additional, Bua, A., additional, Campo, S., additional, Nasisi, P., additional, Salerno, A., additional, Laudani, S., additional, Grippaldi, F., additional, Bertino, D., additional, Di Benedetto, D.V., additional, Puglisi, A., additional, Chiarenza, S., additional, Lentini Deuscit, M., additional, Incardona, C.M., additional, Scuto, G., additional, Todaro, C., additional, Dino, A., additional, Novello, D., additional, Coco, A., additional, Bocheńska-Nowacka, E., additional, Jaroszyński, A., additional, Drabik, J., additional, Wypych-Birecka, M., additional, Daniewska, D., additional, Drobisz, M., additional, Doskocz, K., additional, Wyrwicz-Zielińska, G., additional, Kosicki, A., additional, Ślizień, W., additional, Rutkowski, P., additional, Arentowicz, S., additional, Dzimira, S., additional, Grabowska, M., additional, Ostrowski, J., additional, Całka, A., additional, Grzegorczyk, T., additional, Dżugan, W., additional, Mazur, M., additional, Myślicki, M., additional, Piechowska, M., additional, Kozicka, D., additional, de Sá Martins, V., additional, Aguiar, L., additional, Mira, A.R., additional, Velez, B., additional, Pinheiro, T., additional, Agapi, E., additional, Ardelean, C.L., additional, Baidog, A., additional, Bako, G., additional, Barb, M., additional, Blaga, A., additional, Bodurian, E., additional, Bumbea, V., additional, Dragan, E., additional, Dumitrache, D., additional, Florescu, L., additional, Havasi, N., additional, Hint, S., additional, Ilies, R., additional, Mandita, A.G.M., additional, Marian, R.I., additional, Medrihan, S.L., additional, Mitea, L., additional, Mitea, S., additional, Mocanu, R., additional, Moro, D.C., additional, Nitu, M., additional, Popa, M.L., additional, Popa, M., additional, Railean, E., additional, Scuturdean, A.R., additional, Szentendrey, K., additional, Teodoru, C.L., additional, Varga, A., additional, García, M., additional, Olaya, M., additional, Abujder, V., additional, Carreras, J., additional, López, A., additional, Ros, F., additional, Cuesta, G., additional, García, A., additional, Orero, E., additional, Ros, E., additional, Bea, S., additional, Pizarro, J.L., additional, Luengo, S., additional, Romero, A., additional, Navarro, M., additional, Cermeño, L., additional, Rodriguez, A., additional, Lopez, D., additional, Barrera, A., additional, Montoya, F., additional, Tajahuerce, J., additional, Carro, M., additional, Cunill, M.Q., additional, Narci, S., additional, Ballester, T., additional, Soler, M.J., additional, Traver, S., additional, Buta, P.P., additional, Cucuiat, L., additional, Rosu, L., additional, Garcia, I., additional, Gavra, C.M., additional, Gonzalez, R., additional, Filimon, S., additional, Peñalver, M., additional, Benages, V., additional, Cardo, M.I., additional, García, E., additional, Soler, P., additional, Fernnandez, E., additional, Popescu, F., additional, Munteanu, R., additional, Tanase, E., additional, Sagau, F., additional, Prades, D., additional, Esteller, S., additional, Gonzalez, E., additional, Martinez, R., additional, Diago, A., additional, Torres, J., additional, Perez, E., additional, Garcia, C., additional, Lluch, I., additional, Forcano, J., additional, Fóns, M., additional, Rodríguez, A., additional, Millán, N.A., additional, Fernández, J., additional, Ferreiro, B., additional, Otero, M., additional, Pesqueira, V., additional, Abal, S., additional, Álvarez, R., additional, Jorge, C., additional, Rico, I., additional, de Dios Ramiro, J., additional, Duzy, L., additional, Soto, A., additional, Lopez, J.L., additional, Diaz, Y., additional, Herrero, I., additional, Farré, M., additional, Blasco, C., additional, Ferrás, S., additional, Agost, M.J., additional, Miracle, C., additional, Farto, J., additional, Goch, J., additional, Katzarski, K.S., additional, Wulcan, A., additional, Akbiber, H., additional, Arslan, H., additional, Bicen, L., additional, Buyukkiraz, A., additional, Celik, R., additional, Dogan, I.S., additional, Erkalkan, S., additional, Ertas, A., additional, Hark, U., additional, Iravul, E., additional, Karakaya, M., additional, Mengu, K., additional, Ongun, S., additional, Ozkan, Z., additional, Ozlu, A., additional, Ozveren, N., additional, Sifil, H.M., additional, Sonmez Turksoz, N., additional, and Yilmaz, Z., additional
- Published
- 2020
- Full Text
- View/download PDF
26. Associations of Cognitive Function and Education Level With All-Cause Mortality in Adults on Hemodialysis: Findings From the COGNITIVE-HD Study
- Author
-
van Zwieten, Anita, primary, Wong, Germaine, additional, Ruospo, Marinella, additional, Palmer, Suetonia C., additional, Teixeira-Pinto, Armando, additional, Barulli, Maria Rosaria, additional, Iurillo, Annalisa, additional, Saglimbene, Valeria, additional, Natale, Patrizia, additional, Gargano, Letizia, additional, Murgo, Marco, additional, Loy, Clement T., additional, Tortelli, Rosanna, additional, Craig, Jonathan C., additional, Johnson, David W., additional, Tonelli, Marcello, additional, Hegbrant, Jörgen, additional, Wollheim, Charlotta, additional, Logroscino, Giancarlo, additional, Strippoli, Giovanni F.M., additional, Cagnazzo, A.V., additional, Antinoro, R., additional, Sambati, M.L., additional, Donatelli, C., additional, Dambrosio, N., additional, Saturno, C., additional, Marangelli, A., additional, Pedone, F., additional, Matera, G., additional, Benevento, M., additional, Papagni, S., additional, Alicino, F., additional, Latassa, G., additional, Molino, A., additional, Grippaldi, F., additional, Bertino, D., additional, Montalto, G., additional, Messina, S., additional, Campo, S., additional, Nasisi, P., additional, Failla, A., additional, Bua, A., additional, Pagano, S., additional, Marino, G., additional, Sanfilippo, N., additional, Rallo, D., additional, Maniscalco, A., additional, Capostagno, C., additional, Randazzo, G., additional, Fici, M., additional, Lupo, A., additional, Fichera, R., additional, D'angelo, A., additional, Di Toro Mammarella, R., additional, Meconizzi, M., additional, Boccia, E., additional, Mantuano, M., additional, Flammini, A., additional, and Moscardelli, L., additional
- Published
- 2019
- Full Text
- View/download PDF
27. MetaLiverCat: the NAFLD/NASH multidisciplinary board at Fondazione Policlinico Gemelli IRCCS
- Author
-
Miele, L., primary, Ponziani, F.R., additional, Liguori, A., additional, Nicoletti, A., additional, Fianchi, F., additional, Nesci, A., additional, De Leva, F., additional, Marini, M.G., additional, Aquilanti, B., additional, Matera, G., additional, Casa, S. Della, additional, De Magistris, A., additional, Gagliardi, L., additional, Marrone, G., additional, Biolato, M., additional, Pizzolante, F., additional, De Matthaeis, N., additional, Salvatore, L., additional, Guidone, C., additional, Zocco, M.A., additional, Pitocco, D., additional, De Gaetano, A.M., additional, De Simone, C., additional, Santoloquido, A., additional, Mingrone, G., additional, Raffaelli, M., additional, Miggiano, G.A., additional, Manfredi, R., additional, Vecchio, F.M., additional, Giaccari, A., additional, Pompili, M., additional, Grieco, A., additional, and Gasbarrini, A., additional
- Published
- 2019
- Full Text
- View/download PDF
28. Clinical outcomes of patients treated with intravenous zanamivir for severe influenza A(H1N1)pdm09 infection: A case report series
- Author
-
Torti, C., Mazzitelli, M., Longhini, F., Garofalo, E., Bruni, A., Giancotti, A., Barreca, G. S., Quirino, A., Liberto, M. C., Serapide, F., Matera, G., Trecarichi, E. M., Navalesi, P., Pisani, V., Costa, C., Greco, G., Scaglione, V., Lionello, R., La Gamba, V., Biamonte, E., La Valle, O., Cimino, G., La Torre, P., Karim, A., and Gemelli, A.
- Subjects
0301 basic medicine ,medicine.medical_specialty ,medicine.medical_treatment ,030106 microbiology ,Case Report ,Severe influenza ,Antiviral Agents ,law.invention ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,Influenza A Virus, H1N1 Subtype ,0302 clinical medicine ,Zanamivir ,Medical microbiology ,Randomized controlled trial ,law ,Internal medicine ,Influenza, Human ,ECMO ,ICU ,Influenza A(H1N1)pdm09 ,Humans ,medicine ,Extracorporeal membrane oxygenation ,Influenza A Virus ,lcsh:RC109-216 ,H1N1 Subtype ,030212 general & internal medicine ,Mechanical ventilation ,business.industry ,virus diseases ,Intensive care unit ,Influenza ,respiratory tract diseases ,Infectious Diseases ,Concomitant ,business ,medicine.drug ,Human - Abstract
Background Intravenous (IV) zanamivir could be a suitable alternative for the treatment of severe influenza A(H1N1)pdm09 infection in patients who are unable to take oral or inhaled medication, for example, those on mechanical ventilation and extracorporeal membrane oxygenation (ECMO). However, data on the clinical outcomes of such patients is limited. Case presentation We report the clinical outcomes of four patients who were admitted at the intensive care unit during the 2017–2018 influenza season with severe sepsis (SOFA score > 11) and acute respiratory distress syndrome requiring ECMO and mechanical ventilation. Two patients were immune-compromised. The A(H1N1)pdm09 genome was confirmed by polymerase chain reaction (PCR) on nasopharyngeal specimen swabs prior to administration of IV zanamivir at a dose of 600 mg twice daily. Weekly qualitative PCR analysis was done to monitor viral clearance, with zanamivir treatment being discontinued upon receipt of negative results. In addition, the patients were managed for concomitant multidrug-resistant bacterial infections, with infection resolution confirmed with blood cultures. The median time for zanamivir treatment was 10 days (IQR 10–17). The clinical outcome was favourable with all four patients surviving and improving clinically. All four patients achieved viral clearance of A(H1N1)pdm09 genome, and resolution of multidrug-resistant bacterial infections. Conclusions IV zanamivir could be a good therapeutic option in patients with severe influenza A(H1N1)pdm09 infection who are unable to take oral or aerosolised antiviral medication. We recommend prospective randomized control trials to support this hypothesis.
- Published
- 2019
29. Inhibition of endotoxin-induced interleukin 8 release by teicoplanin in human whole blood
- Author
-
Focà, A., Matera, G., and Berlinghieri, M. C.
- Published
- 1993
- Full Text
- View/download PDF
30. Procalcitonin, IL-10 and sCD25 as diagnostic and prognostic markers in critically ill patients
- Author
-
Focà, A, Liberto, MC, Rametti, L, Giancotti, A, Marascio, N, Quirino, A, Caroleo, S, Renzulli, A, and Matera, G
- Published
- 2012
- Full Text
- View/download PDF
31. Polynomial equation solving by lifting procedures for ramified fibers
- Author
-
Bompadre, A., Matera, G., Wachenchauzer, R., and Waissbein, A.
- Published
- 2004
- Full Text
- View/download PDF
32. Laser processing of TiSi2 and CoSi2 thin films on silicon (100) substrates
- Author
-
Tiwari, P., Longo, Mary, Matera, G., Sharan, S., Smith, P. L., and Narayan, J.
- Published
- 1991
- Full Text
- View/download PDF
33. Growth of diamond films on si(100) with and without boron nitride buffer layer
- Author
-
Kanetkar, S. M., Matera, G., Chen, Xuekang, Pramanick, S., Tiwari, P., Narayan, J., Pfeiffer, G., and Paesler, M.
- Published
- 1991
- Full Text
- View/download PDF
34. Enhancement of nucleation and adhesion of diamond films on copper, stainlesssteel, and silicon substrates
- Author
-
Narayan, J., Godbole, V.P., Matera,G., and Singh, R.K.
- Subjects
Nucleation -- Research ,Diamond films -- Research ,Adhesion -- Research ,Physics - Abstract
Aprocess forenhancing and nucleation and adhesion of diamond films on nondiamond substratesis described. The process uses pulsed laser irradiation to convert amorphous carbon on the substrate surface to the diamond phase and thus enhance nucleation. In addition, the laser is capable of selectively evaporating carbonwhile leaving the diamond particles unaffected. Pulsed laser irradiation can melt the substrate and embed diamond particles into it.
- Published
- 1992
35. Fast computation of discrete invariants associated to a differential rational mapping
- Author
-
Matera, G. and Sedoglavic, A.
- Published
- 2003
- Full Text
- View/download PDF
36. PF436 GMP MANUFACTURING OF ALLOGENEIC CD19 CHIMERIC ANTIGEN RECEPTOR (CAR) CYTOKINE INDUCED KILLER (CIK) CELLS WITH SLEEPING BEAUTY (SB) TRANSPOSON FOR ADOPTIVE IMMUNOTHERAPY
- Author
-
Magnani, C.F., primary, Gaipa, G., additional, Belotti, D., additional, Matera, G., additional, Tettamanti, S., additional, Cabiati, B., additional, Cesana, S., additional, Colombo, V., additional, Cazzaniga, G., additional, Fazio, G., additional, Buracchi, C., additional, Rigamonti, S., additional, Rovelli, A., additional, Balduzzi, A., additional, Napolitano, S., additional, Montini, E., additional, Borleri, G.M., additional, Gritti, G., additional, Lussana, F., additional, Introna, M., additional, Rambaldi, A., additional, Dastoli, G., additional, and Biondi, A., additional
- Published
- 2019
- Full Text
- View/download PDF
37. Functional programming concepts and straight-line programs in computer algebra
- Author
-
Bruno, N., Heintz, J., Matera, G., and Wachenchauzer, R.
- Published
- 2002
- Full Text
- View/download PDF
38. Bartonellae: Stealthy pathogens or novel drug factories (Letter to the Editorial Board of Biokhimiya/Biochemistry (Moscow))
- Author
-
Matera, G., Quirino, A., Lamberti, A. G., Focà, A., and Liberto, M. C.
- Published
- 2011
- Full Text
- View/download PDF
39. A new method to obtain lower bounds for polynomial evaluation
- Author
-
Aldaz, M., Matera, G., Montaña, J.L., and Pardo, L.M.
- Published
- 2001
- Full Text
- View/download PDF
40. Vegetation map of 'Zone Umide della Capitanata' (SCI IT9110005)
- Author
-
Veronico G., Sciandrello S., Matera G., and Tomaselli V.
- Subjects
coastal wetland ,Capitanata ,Vegetation map - Abstract
This article illustrates the vegetation map of the SCI "Zone umide della Capitanata" (IT 9110005) a wetland area of South Italy (Apulia Region). The SCI "Zone Umide della Capitanata" is one of the most important Italian coastal wetlands and it covers about 14.000 ha, part of which is exploited for marine salt production. The site is characterized by a wetlands complex in coastal environment, with highly fragmented landscape because of anthropogenic activities (mainly herbaceous crops). This study aims at assessing presence and distribution of vegetation types that, despite strong human pressure, still maintain good natural habitat conditions. Thematic maps were digitized in ArcGis 10.2 from recent orthophotos in ombination with topographical maps (1:5.000). In case of fragmented areas, vegetation mosaics were adopted. The extent of complex vegetation mosaics is wider in those areas where anthropogenic activities are stronger.
- Published
- 2017
41. Eicosanoids in sepsis and its sequelae
- Author
-
Cook, J. A., Tempel, G. E., Ball, H. A., Wise, W. C., Matera, G., Reines, H. D., Halushka, P. V., Hillier, Keith, editor, Halushka, P. V., editor, and Mais, D. E., editor
- Published
- 1988
- Full Text
- View/download PDF
42. Is it time to move from standard to targeted surgical prophylaxis?
- Author
-
Quirino, A., primary, Torti, C., additional, Cortese, G., additional, Morelli, P., additional, Reale, M.C., additional, Mastroroberto, P., additional, Matera, G., additional, Liberto, M.C., additional, and Focà, A., additional
- Published
- 2016
- Full Text
- View/download PDF
43. Nutrition and dietary intake and their association with mortality and hospitalisation in adults with chronic kidney disease treated with haemodialysis: protocol for DIET-HD, a prospective multinational cohort study
- Author
-
Palmer, Sc, Ruospo, M, Campbell, Kl, Garcia Larsen, V, Saglimbene, V, Natale, P, Gargano, L, Craig, Jc, Johnson, Dw, Tonelli, M, Knight, J, Bednarek Skublewska, A, Celia, E, Del Castillo, D, Dulawa, J, Ecder, T, Fabricius, E, Frazão, Jm, Gelfman, R, Hoischen, Sh, Schön, S, Stroumza, P, Timofte, D, Török, M, Hegbrant, J, Wollheim, C, Frantzen, L, Strippoli, Gf, Raña, S, Serrano, M, Claros, S, Arias, M, Petracci, L, Arana, M, De Rosa, P, Gutierrez, A, Simon, M, Vergara, V, Tosi, M, Cernadas, M, Vilamajó, I, Gravac, D, Paulón, M, Penayo, L, Carrizo, G, Ghiani, M, Perez, G, Da Cruz, O, Galarce, D, Gravielle, M, Vescovo, E, Paparone, R, Mato Mira, C, Mojico, E, Hermida, O, Florio, D, Yucoswky, M, Labonia, W, Rubio, D, Di Napoli, G, Fernandez, A, Altman, H, Rodriguez, J, Serrano, S, Valle, G, Lobos, M, Acosta, V, Corpacci, G, Jofre, M, Gianoni, L, Chiesura, G, Capdevila, M, Montenegro, J, Bequi, J, Dayer, J, Gómez, A, Calderón, C, Abrego, E, Cechín, C, García, J, Corral, J, Natiello, M, Coronel, A, Muñiz, M, Muñiz, V, Bonelli, A, Sanchez, F, Maestre, S, Olivera, S, Camargo, M, Avalos, V, Geandet, E, Canteli, M, Escobar, A, Sena, E, Tirado, S, Peñalba, A, Neme, G, Cisneros, M, Oliszewski, R, Nascar, V, Daud, M, Mansilla, S, Paredes Álvarez, A, Gamín, L, Arijón, M, Coombes, M, Zapata, M, Boriceanu, C, Lankester, M, Poignet, Jl, Saingra, Y, Indreies, M, Santini, J, Amar, M, Robert, A, Bouvier, P, Merzouk, T, Villemain, F, Pajot, A, Tollis, F, Brahim Bounab, M, Benmoussa, A, Albitar, S, Guimont, Mc, Ciobotaru, P, Guerin, A, Diaconita, M, Shh, Saupe, J, Ullmann, I, Grosser, S, Kunow, J, Grueger, S, Bischoff, D, Benders, J, Worch, P, Pfab, T, Kamin, N, Roesch, M, Albert, K, Csaszar, I, Kiss, E, Kosa, D, Orosz, A, Redl, J, Kovacs, L, Varga, E, Szabo, M, Magyar, K, Zajko, E, Bereczki, A, Csikos, J, Kerekes, E, Mike, A, Steiner, K, Nemeth, E, Tolnai, K, Toth, A, Vinczene, J, Szummer, S, Tanyi, E, Szilvia, M, Murgo, Am, Sanfilippo, N, Dambrosio, N, Saturno, C, Matera, G, Benevento, M, Greco, V, di Leo, G, Papagni, S, Alicino, F, Marangelli, A, Pedone, F, Cagnazzo, Av, Antinoro, R, Sambati, Ml, Donatelli, C, Ranieri, F, Torsello, F, Steri, P, Riccardi, C, Flammini, A, Moscardelli, L, Boccia, E, Mantuano, M, Di Toro Mammarella, R, Meconizzi, M, Fichera, R, D'Angelo, A, Latassa, G, Molino, A, Fici, M, Lupo, Antonio, Montalto, G, Messina, S, Capostagno, C, Randazzo, G, Pagano, S, Marino, G, Rallo, D, Maniscalco, A, Trovato, Om, Strano, C, Failla, A, Bua, A, Campo, S, Nasisi, P, Salerno, A, Laudani, S, Grippaldi, F, Bertino, D, Di Benedetto, Dv, Puglisi, A, Chiarenza, S, Lentini Deuscit, M, Incardona, Cm, Scuto, G, Todaro, C, Dino, A, Novello, D, Coco, A, Bocheńska Nowacka, E, Jaroszyński, A, Drabik, J, Wypych Birecka, M, Daniewska, D, Drobisz, M, Doskocz, K, Wyrwicz Zielińska, G, Kosicki, A, Ślizień, Ws, Rutkowski, P, Arentowicz, S, Dzimira, S, Grabowska, M, Ostrowski, J, Całka, A, Grzegorczyk, T, Dżugan, W, Mazur, M, Myślicki, M, Piechowska, M, Kozicka, D, Mira, Ar, Martins, V, Velez, B, Pinheiro, T, Agapi, E, Ardelean, Cl, Baidog, A, Bako, G, Barb, M, Blaga, A, Bodurian, E, Bumbea, V, Dragan, E, Dumitrache, D, Florescu, L, Havasi, N, Hint, S, Ilies, R, Mandita, Ag, Marian, Ri, Medrihan, Sl, Mitea, L, Mitea, S, Mocanu, R, Moro, Dc, Nitu, M, Popa, Ml, Popa, M, Railean, E, Scuturdean, Ar, Szentendrey, K, Teodoru, Cl, Varga, A, Bernat, A, De la Torre, B, Lopez, A, Martin, J, Cuesta, G, Rodriguez, Rm, Ros, F, Garcia, M, Orero, E, Ros, E, Goch, J, Katzarski, Ks, Wulcan, A, Akbiber, H, Arslan, H, Bicen, L, Buyukkiraz, A, Celik, R, Dogan, Is, Erkalkan, S, Ertas, A, Hark, U, Iravul, E, Karakaya, M, Mengu, K, Ongun, S, Ozkan, Z, Ozlu, A, Ozveren, N, Sifil, Hm, Sonmez Turksoz, N, and Yilmaz, Z.
- Subjects
Adult ,Male ,medicine.medical_specialty ,Pediatrics ,Adolescent ,Turkey ,medicine.medical_treatment ,Argentina ,NUTRITION & DIETETICS ,Nutritional Status ,Infections ,Young Adult ,Informed consent ,Renal Dialysis ,Cause of Death ,Fatty Acids, Omega-6 ,Epidemiology ,Fatty Acids, Omega-3 ,medicine ,Protocol ,Humans ,EPIDEMIOLOGY ,Social determinants of health ,hemodialysis ,Prospective Studies ,Prospective cohort study ,Dialysis ,Renal Medicine ,business.industry ,Other Research Radboud Institute for Health Sciences [Radboudumc 0] ,General Medicine ,medicine.disease ,Europe ,Hospitalization ,Cardiovascular Diseases ,Food ,Research Design ,Emergency medicine ,Kidney Failure, Chronic ,Female ,Hemodialysis ,business ,Energy Intake ,Kidney disease ,Cohort study - Abstract
Contains fulltext : 153534.pdf (Publisher’s version ) (Open Access) INTRODUCTION: Adults with end-stage kidney disease (ESKD) treated with haemodialysis experience mortality of between 15% and 20% each year. Effective interventions that improve health outcomes for long-term dialysis patients remain unproven. Novel and testable determinants of health in dialysis are needed. Nutrition and dietary patterns are potential factors influencing health in other health settings that warrant exploration in multinational studies in men and women treated with dialysis. We report the protocol of the "DIETary intake, death and hospitalisation in adults with end-stage kidney disease treated with HaemoDialysis (DIET-HD) study," a multinational prospective cohort study. DIET-HD will describe associations of nutrition and dietary patterns with major health outcomes for adults treated with dialysis in several countries. METHODS AND ANALYSIS: DIET-HD will recruit approximately 10,000 adults who have ESKD treated by clinics administered by a single dialysis provider in Argentina, France, Germany, Hungary, Italy, Poland, Portugal, Romania, Spain, Sweden and Turkey. Recruitment will take place between March 2014 and June 2015. The study has currently recruited 8000 participants who have completed baseline data. Nutritional intake and dietary patterns will be measured using the Global Allergy and Asthma European Network (GA(2)LEN) food frequency questionnaire. The primary dietary exposures will be n-3 and n-6 polyunsaturated fatty acid consumption. The primary outcome will be cardiovascular mortality and secondary outcomes will be all-cause mortality, infection-related mortality and hospitalisation. ETHICS AND DISSEMINATION: The study is approved by the relevant Ethics Committees in participating countries. All participants will provide written informed consent and be free to withdraw their data at any time. The findings of the study will be disseminated through peer-reviewed journals, conference presentations and to participants via regular newsletters. We expect that the DIET-HD study will inform large pragmatic trials of nutrition or dietary interventions in the setting of advanced kidney disease.
- Published
- 2015
44. COGNITIVE-HD study: protocol of an observational study of neurocognitive functioning and association with clinical outcomes in adults with end-stage kidney disease treated with haemodialysis
- Author
-
Palmer, Sc, Ruospo, M, Barulli, Mr, Iurillo, A, Saglimbene, V, Natale, P, Gargano, L, Murgo, Am, Loy, C, van Zwieten, A, Wong, G, Tortelli, R, Craig, Jc, Johnson, Dw, Tonelli, M, Hegbrant, J, Wollheim, C, Logroscino, G, Strippoli, Gf, Cagnazzo, A, Antinoro, R, Sambati, M, Donatelli, C, Dambrosio, N, Saturno, C, Marangelli, A, Pedone, F, Matera, G, Benevento, M, Papagni, S, Alicino, F, Latassa, G, Molino, A, Grippaldi, F, Bertino, D, Montalto, G, Messina, S, Campo, S, Nasisi, P, Failla, A, Bua, A, Pagano, S, Marino, G, Sanfilippo, N, Rallo, D, Maniscalco, A, Capostagno, C, Randazzo, G, Fici, M, Lupo, Antonio, Fichera, R, D'Angelo, A, Region, L, Mammarella, Rd, Meconizzi, M, Boccia, E, Mantuano, M, Flammini, A, and Moscardelli, L.
- Subjects
Adult ,Pediatrics ,medicine.medical_specialty ,Patient Dropouts ,Adolescent ,Epidemiology ,medicine.medical_treatment ,Population ,Neuropsychological Tests ,Executive Function ,Cognition ,Clinical Protocols ,Memory ,Renal Dialysis ,Informed consent ,Cause of Death ,Activities of Daily Living ,Protocol ,medicine ,Humans ,Learning ,Longitudinal Studies ,Prospective Studies ,Prospective cohort study ,education ,Dialysis ,cognitive impairment ,education.field_of_study ,hemodialysis ,business.industry ,General Medicine ,medicine.disease ,Treatment Outcome ,Italy ,Motor Skills ,Research Design ,cognitive impairment, chronic kidney disease, hemodialysis ,Kidney Failure, Chronic ,Cognition Disorders ,business ,Neurocognitive ,chronic kidney disease ,Kidney disease ,Cohort study - Abstract
Introduction The prevalence of cognitive impairment may be increased in adults with end-stage kidney disease compared with the general population. However, the specific patterns of cognitive impairment and association of cognitive dysfunction with activities of daily living and clinical outcomes (including withdrawal from treatment) among haemodialysis patients remain incompletely understood. The COGNITIVE impairment in adults with end-stage kidney disease treated with HemoDialysis (COGNITIVE-HD) study aims to characterise the age-adjusted and education-adjusted patterns of cognitive impairment (using comprehensive testing for executive function, perceptual-motor function, language, learning and memory, and complex attention) in patients on haemodialysis and association with clinical outcomes. Methods and analysis A prospective, longitudinal, cohort study of 750 adults with end-stage kidney disease treated with long-term haemodialysis has been recruited within haemodialysis centres in Italy (July 2013 to April 2014). Testing for neurocognitive function was carried out by a trained psychologist at baseline to assess cognitive functioning. The primary study factor is cognitive impairment and secondary study factors will be specific domains of cognitive function. The primary outcome will be total mortality. Secondary outcomes will be cause-specific mortality, major cardiovascular events, fatal and non-fatal myocardial infarction and stroke, institutionalisation, and withdrawal from treatment at 12 months. Ethics and dissemination This protocol was approved before study conduct by the following responsible ethics committees: Catania (approval reference 186/BE; 26/09/2013), Agrigento (protocol numbers 61–62; 28/6/2013), USL Roma C (CE 39217; 24/6/2013), USL Roma F (protocol number 0041708; 23/7/2013), USL Latina (protocol number 20090/A001/2011; 12/7/2013), Trapani (protocol number 3413; 16/7/2013) and Brindisi (protocol number 40259; 6/6/2013). All participants have provided written and informed consent and can withdraw from the study at any time. The findings of the study will be disseminated through peer-reviewed journals and national and international conference presentations and to the participants through communication within the dialysis network in which this study is conducted.
- Published
- 2015
45. Enhancement of nucleation and adhesion of diamond films on copper, stainless steel, and silicon substrates.
- Author
-
Narayan, J., Godbole, V. P., Matera, G., and Singh, R. K.
- Subjects
NUCLEATION ,ADHESION ,DIAMONDS ,THIN films - Abstract
Reports on the enhancement of nucleation and adhesion of diamond films on copper, stainless steel, and silicon substrates. Categories of the nondiamond substrates deposited in diamond thin films; Details on the experiment; Discussion on the results of the experiment.
- Published
- 1992
- Full Text
- View/download PDF
46. Phenotypic and genotypic evaluation of slime production by conventional and molecular microbiological techniques
- Author
-
LIBERTO MC, MATERA G, QUIRINO A, LAMBERTI AG, CAPICOTTO R, PUCCIO R, BARRECA, FOCA E, CASCIO A., FOCA A, LIBERTO MC, MATERA G, QUIRINO A, LAMBERTI AG, CAPICOTTO R, PUCCIO R, BARRECA, GS, FOCA E, CASCIO A., and FOCA A
- Subjects
Coagulase-negative staphylococci ,Ica genes ,Real-time PCR ,Slime ,Bacterial Capsules ,Bacterial Proteins ,Bacteriological Techniques ,Genotype ,Humans ,Phenotype ,Polymerase Chain Reaction ,Staining and Labeling ,Staphylococcal Infections ,Staphylococcus ,Microbiology ,ICAD ,Biology ,Agar plate ,Gene expression ,Gene ,Molecular biology ,Real-time polymerase chain reaction ,Slime, Real-time PCR, Coagulase-negative, staphylococci, Ica genes ,Coagulase - Abstract
Twenty-nine staphylococcal isolates from different clinical samples were tested for slime production: phenotypic characterization was carried out using Christensen test (tube test) and Congo red agar plate test (CRA plate test), while the presence and expression of icaA and icaD genes were evaluated by real-time PCR. In 79.3% of studied strains there was a concordance between slime production and presence of icaA and icaD genes, and between lack of slime production and absence of both or only one of the tested genes. In four of five strains where positive phenotype was not associated with the presence of ica genes, gene co-expression (evaluated by mRNA determination) was lacking, while in only a case out of five, there was the presence of transcripts without phenotype. Our study, for the first time, introduces real-time PCR for the detection of both icaA and icaD genes and their mRNA and, furthermore, addresses the relationship between slime phenotype absence and mRNA expression, in clinical isolates of coagulase-negative staphylococci.
- Published
- 2006
47. 57 Improving Fracture Care in an Emergency Department
- Author
-
Callahan, J.M., primary, Baldwin, K.D., additional, Wood, M., additional, Valente, C., additional, Funari, M.K., additional, Johnson, T., additional, Freedman, R., additional, Matera, G., additional, Zorc, J.J., additional, and Schast, A., additional
- Published
- 2015
- Full Text
- View/download PDF
48. Six cases of sepsis caused by Pantoea agglomerans in a teaching hospital
- Author
-
Liberto, M. C., Matera, G., Puccio, R., Lo Russo, T., Colosimo, E., and Emanuele FOCA'
- Subjects
Adult ,Male ,Cross Infection ,Pantoea ,Teaching ,Microbial Sensitivity Tests ,Middle Aged ,Hospitals ,Aged ,Anti-Bacterial Agents ,Female ,Gram-Negative Bacterial Infections ,Humans ,Italy ,Sepsis ,Disease Outbreaks ,Hospitals, Teaching - Abstract
Pantoea agglomerans is an environmental organism which may seldom cause opportunistic infections. Here we report on a 6 case outbreak in a teaching hospital. Within three months . agglomerans was isolated from blood cultures of 5 patients from oncology and 1 patient from ICU departments. P. agglomerans was in pure culture in 5 cases, while in the last one Rahnella aquatilis and Candida famata were also isolated. Therefore, P. agglomerans is able to produce nosocomial infections in patients with primary pathology often associated with immune suppression.
- Published
- 2009
49. The Janus face of Bartonella quintana recognition by Toll-like receptors (TLRs): a review
- Author
-
Matera, G., Liberto, M.C., Joosten, L.A.B., Vinci, M., Quirino, A., Pulicari, M.C., Kullberg, B.J., Meer, J.W.M. van der, Netea, M.G., and Foca, A.
- Subjects
Pathogenesis and modulation of inflammation [N4i 1] ,Invasive mycoses and compromised host [N4i 2] ,Chronic inflammation and autoimmunity [UMCN 4.2] ,Perception and Action [DCN 1] ,bacteria ,lipids (amino acids, peptides, and proteins) ,Microbial pathogenesis and host defense [UMCN 4.1] ,bacterial infections and mycoses ,Auto-immunity, transplantation and immunotherapy [N4i 4] ,Infection and autoimmunity [NCMLS 1] ,Immunity, infection and tissue repair [NCMLS 1] - Abstract
Contains fulltext : 70849.pdf (Publisher’s version ) (Closed access) Bartonella quintana (B. quintana) is a facultative, intracellular bacterium, which causes trench fever, chronic bacteraemia and bacillary angiomatosis. Little is known about the recognition of B. quintana by the innate immune system. In this review, we address the impact of Toll-like receptors (TLRs) on the recognition of B. quintana and the activation of the host defense. When experimental models using human mononuclear cells, transfected CHO cells, or TLR2-/- and TLR4-/- mice were used, differential effects of TLR2 and TLR4 have been observed. B. quintana micro-organisms stimulated cytokine production through TLR2-mediated signals, whereas no role for TLR4 in the recognition of this pathogen was observed. When single, water-phenol extraction was performed, B. quintana LPS, stimulated cytokine production in a TLR2-dependent manner. However, when double extraction was performed in order to generate highly purified LPS, B. quintana LPS entirely lost its capacity to stimulate cytokines, demonstrating that non-LPS components of B. quintana are responsible for the recognition through TLR2. Moreover, B. quintana LPS was shown to be a potent antagonist of Toll-like receptor 4 (TLR4). In conclusion, B. quintana is an inducer of cytokines through TLR2-, but not TLR4-, dependent mechanisms. This stimulation is induced by bacterial components other than lipopolysaccharide. B. quintana LPS is a naturally occurring antagonist of Toll-like receptor 4 (TLR4). In view of the role played by TLR4 in inflammation, B. quintana LPS may be useful as an anti-TLR4 agent with therapeutic potential in both infections and autoimmune inflammation.
- Published
- 2008
50. Phenotypic and genotypic evaluation of slimeproduction by conventional and molecularmicrobiological techniques
- Author
-
Liberto, Mc, Matera, G, Quirino, A, Lamberti, Ag, Capicotto, R, Puccio, R, Barreca, Gs, Foca, E, Cascio, Antonio, and Foca, A.
- Published
- 2007
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.