4 results on '"Matej Vogrincic"'
Search Results
2. Towards New User Interfaces Based on Gesture and Sound Identification.
- Author
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Kristijan Kosic, Bostjan Arzensek, Matej Vogrincic, and Sasa Kuhar
- Published
- 2013
3. The Use of Biopsy and 'No-Biopsy' Approach for Diagnosing Paediatric Coeliac Disease in the Central European Region
- Author
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Daniele Sblattero, Tarcisio Not, Ildikó Guthy, Martina Klemenak, Tomaz Krencnik, Piroska Bodi, István Tokodi, M Balogh, Luigina De Leo, Sibylle Koletzko, Judit Gyimesi, Matej Vogrincic, Éva Pollák, Petra Riznik, Katharina Julia Werkstetter, Ilma Rita Korponay-Szabó, Berthold Koletzko, Ildikó Kis, Jernej Dolinsek, Jasmina Dolinsek, Goran Palčevski, Agnes Horvath, Riznik, P., Balogh, M., Bodi, P., De Leo, L., Dolinsek, J., Guthy, I., Gyimesi, J., Horvath, A., Kis, I., Klemenak, M., Koletzko, B., Koletzko, S., Korponay-Szabo, I. R., Krencnik, T., Not, T., Palcevski, G., Pollak, E., Sblattero, D., Tokodi, I., Vogrincic, M., Werkstetter, K. J., and Rybak, A.
- Subjects
medicine.medical_specialty ,Pediatrics ,Malabsorption ,Article Subject ,diagnosis ,Biopsy ,intestinal biopsy ,Asymptomatic ,Coeliac disease ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,030225 pediatrics ,Internal medicine ,medicine ,lcsh:RC799-869 ,Celiac Diseases ,Transglutaminases ,Hepatology ,medicine.diagnostic_test ,business.industry ,Central Europe ,Medical record ,Gastroenterology ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Pedijatrija ,medicine.disease ,diagnosi ,Cohort ,celiac disease ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Pediatrics ,030211 gastroenterology & hepatology ,lcsh:Diseases of the digestive system. Gastroenterology ,celiac diseases ,transglutaminases ,biopsy ,cohort studies ,medicine.symptom ,business ,Cohort study ,Research Article - Abstract
Objectives. The current European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) guidelines introduced the option to diagnose coeliac disease (CD) in children and adolescents without upper endoscopy if the defined criteria are met. The aim of our study was to evaluate how frequently paediatric gastroenterologists in Central Europe used the “no-biopsy” approach and how often the duodenal biopsy could have been omitted. Methods. Medical records of patients aged<19 years diagnosed with CD in 2016 from five European countries were analysed, focusing on levels of transglutaminase antibodies (TGA) at the time of diagnosis and on whether the diagnosis was confirmed using duodenal biopsy or “no-biopsy” approach. Clinical presentation and delays until final diagnosis were analysed according to diagnostic approach. Results. Data from 653 children (63.9% female, median age: 7 years, range: 7 months-18.5 years) from Croatia, Hungary, Germany, Italy, and Slovenia were analysed. One fifth (n=134) of included children were asymptomatic at diagnosis. Of 519 symptomatic children, 107 (20.6%) were diagnosed by the “no-biopsy” approach. Out of the remaining 412 children who underwent duodenal biopsies, 214 (51.9%) had TGA≥10 times upper level of normal (ULN) and would have been eligible for the “no-biopsy” approach. Signs and symptoms of malabsorption were more frequent in children diagnosed without duodenal biopsies. There were no differences in diagnostic delays with respect to the diagnostic approach. Conclusion. In this cohort, about 60% of symptomatic CD patients could have been diagnosed without duodenal biopsies. The aim of the “no-biopsy” approach was to make the diagnostic procedure less challenging without compromising its reliability. However, this option was applied only in 20%, in spite of fewer burdens to the family and reduced costs. The reasons for this discrepancy are unknown. Physicians should be made more aware about the reliability of CD diagnosis without biopsies when the ESPGHAN guidelines for CD diagnosis are followed.
- Published
- 2019
4. Diagnostic Delays in Children With Coeliac Disease in the Central European Region
- Author
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Tarcisio Not, Goran Palčevski, Matej Vogrincic, Sibylle Koletzko, Judit Gyimesi, Jasmina Dolinsek, Katharina Julia Werkstetter, Jernej Dolinsek, Martina Klemenak, Daniele Sblattero, Berthold Koletzko, Ilma Rita Korponay-Szabó, Petra Riznik, Tomaz Krencnik, Luigina De Leo, Riznik, Petra, De Leo, Luigina, Dolinsek, Jasmina, Gyimesi, Judit, Klemenak, Martina, Koletzko, Berthold, Koletzko, Sibylle, Korponay-Szabó, Ilma Rita, Krencnik, Tomaz, Not, Tarcisio, Palcevski, Goran, Sblattero, Daniele, Vogrincic, Matej, Werkstetter, Katharina Julia, and Dolinsek, Jernej
- Subjects
Paediatric gastroenterologist ,Male ,Pediatrics ,medicine.medical_specialty ,Delayed Diagnosis ,Adolescent ,Population ,Child Health Services ,Standard score ,Diagnostic tools ,central Europe region ,Coeliac disease ,03 medical and health sciences ,0302 clinical medicine ,030225 pediatrics ,medicine ,Humans ,education ,Child ,celiac disease ,diagnostic delay, central Europe region ,Retrospective Studies ,education.field_of_study ,business.industry ,Gastroenterology ,Infant ,medicine.disease ,European region ,diagnostic delay ,Europe ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,030211 gastroenterology & hepatology ,Female ,Central Europe ,children ,coeliac disease ,diagnostic delays ,business ,Regional differences - Abstract
Objectives: Coeliac disease (CD) is a systemic autoimmune disorder affecting about 1% of the population. Many patients remain undiagnosed or are diagnosed with substantial delay. We assessed diagnostic delays in symptomatic CD children in Central Europe (CE). Methods: Paediatric gastroenterologists in 5 CE countries retrospectively reported data of their patients diagnosed in 2016. Age at first CD-related symptom(s), first visit to paediatric gastroenterologist and confirmed diagnosis were used to determine diagnostic delays. Results: Data from 393 children (65% girls, median age 7 years, range 7 months to 18.5 years) from Croatia, Hungary, Germany, Italy, and Slovenia were analysed. Median duration from first symptom(s) to visit to paediatric gastroenterologist was 5 months (range 0–10 years ; preschool 4 months, school-aged 5 months), and further duration until final diagnosis was 1 month (range 0–5 years) with significant regional differences (P < 0.001). Median diagnostic delay was 6 months (range 0–10 years ; preschool 5 months, school-aged 7 months). Type of clinical presentation had little, however, significant effect on delays. Reduced body mass in delays longer than 3 years compared with delays shorter than 1 year was found (z score −0.93 vs −0.39, P < 0.05). Conclusions: Time from first symptoms to CD diagnosis in children in 5 CE countries is slightly shorter compared with few other small paediatric studies, and significantly shorter than reported for adults. Nevertheless, delays of more than 3 years in 6.6% of children are worrisome. Raising awareness about the variable symptoms and implementation of reliable diagnostic tools will further reduce diagnostic delays
- Published
- 2019
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