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3. Retour triomphant des J2R 2023 à Tours : un tourbillon d’échanges scientifiques et d’émotion

Author

Annesi-Maesano, I., primary, Bonniaud, P., additional, Bouchaud, G., additional, Boyer, L., additional, Gazzeri, S., additional, Gosset, P., additional, Gras, D., additional, Guibert, C., additional, Guignabert, C., additional, Mari, B., additional, Matecki, S., additional, Morélot, C., additional, Pilette, C., additional, Planes, C., additional, Plantier, L., additional, Polette, M., additional, Si-Tahar, M., additional, Taillé, C., additional, and Vachier, I., additional more...

Published
2024
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10. RESPIRenT : RESeau de Pneumologie en Innovation et Recherche translaTionnelle, un nouveau souffle pour les J2R

Author

Annesi-Maesano, I., primary, Bonniaud, P., additional, Bouchaud, G., additional, Boyer, L., additional, Gazzeri, S., additional, Gosset, P., additional, Gras, D., additional, Guibert, C., additional, Guignabert, C., additional, Mari, B., additional, Matecki, S., additional, Morélot, C., additional, Pilette, C., additional, Planes, C., additional, Plantier, L., additional, Polette, M., additional, Si-Tahar, M., additional, Taillé, C., additional, and Vachier, I., additional more...

Published
2022
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17. Assessment of Peak Inspiratory Flow in Young Infants with Acute Viral Bronchiolitis: Physiological Basis for Initial Flow Setting in Patients Supported with High-Flow Nasal Cannula

Author

Milési C, Requirand A, Douillard A, Baleine J, Nogué E, Matecki S, Amedro P, Pons-Odena M, and Cambonie G

Subjects
respiratory syncytial virus infections, respiratory function, high-flow nasal cannula, respiratory distress
Abstract

OBJECTIVE: To assess the inspiratory demand in young infants with acute viral bronchiolitis to provide a physiological basis for initial flow setting for patients supported with high flow nasal cannula. STUDY DESIGN: Prospective study in 44 infants up to 6 months old with acute viral bronchiolitis, admitted to a pediatric intensive care unit from November 2017 to March 2019. Airflow measurements were performed using spirometry. The primary endpoint was the inspiratory demand as measured by peak tidal inspiratory flow (PTIF). The secondary endpoints were the relationships determined between PTIF, patient weight, and disease severity. RESULTS: Median (Q(25)-Q(75)) age and weight of the patients were 37 (20-67) days and 4.3 (3.5-5.0) kg, respectively. Mean PTIF was 7.45 (95% CI 6.51-8.39, min-max: 2.40-16.00) L/minute. PTIF indexed to weight was 1.68 (95% CI 1.51-1.85, min-max: 0.67-3.00) L/kg/minute. PTIF was more...

Published
2021

20. Tonnerre de Brest ! Des Journées de Recherche Respiratoires 2020 pas comme les autres…

Author

Annesi-Maesano, I., primary, Bonniaud, P., additional, Bouchaud, G., additional, Boyer, L., additional, Frossard, N., additional, Gazzeri, S., additional, Gosset, P., additional, Gras, D., additional, Guibert, C., additional, Guignabert, C., additional, Mari, B., additional, Matecki, S., additional, Morelot, C., additional, Pilette, C., additional, Planes, C., additional, Plantier, L., additional, Polette, M., additional, Si-Tahar, M., additional, Taillé, C., additional, and Vachier, I., additional more...

Published
2021
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21. Effect of inspiratory threshold loading on ventilatory kinetics during constant-load exercise

Author

Keslacy, S., Matecki, S., Carra, J., Borrani, F., Candau, R., Prefaut, C., and Ramonatxo, M.

Subjects
Exercise -- Health aspects, Ventilators -- Health aspects, Biological sciences
Abstract

Humoral factors play an important role in the control of exercise hyperpnea. The role of neuromechanical ventilatory factors, however, is still being investigated. We tested the hypothesis that the afferents of the thoracopulmonary system, and consequently of the neuromechanical ventilatory loop, have an influence on the kinetics of oxygen consumption ([Vo.sub.2]), carbon dioxide output ([V.sub.C[O.sub.2]]), and ventilation ([V.sub.E]) during moderate intensity exercise. We did this by comparing the ventilatory time constants ([tau]) of exercise with and without an inspiratory load. Fourteen healthy, trained men (age 22.6 [+ or ] 3.2 yr) performed a continuous incremental cycle exercise test to determine maximal oxygen uptake ([V.sub.[O.sub.2] max] = 55.2 [+ or -] 5.8 ml*[min.sup.-1]*[kg.sup.-1]). On another day, after unloaded warm-up they performed randomized constantload tests at 40% of their [V.sub.[O.sub.2]] for 8 min, one with and the other without an inspiratory threshold load of 15 cm[H.sub.2]O. Ventilatory variables were obtained breath by breath. Phase 2 ventilatory kinetics ([V.sub.2], [V.sub.C[O.sub.2]], and [V.sub.E]) could be described in all cases by a monoexponential function. The bootstrap method revealed small coefficients of variation for the model parameters, indicating an accurate determination for all parameters. Paired Student's t-tests showed that the addition of the inspiratory resistance significantly increased the 'r during phase 2 of [V.sub.[O.sub.2]] (43.1 [+ or -] 8.6 vs. 60.9 [+ or -] 14.1 s; P < 0.001), [V.sub.C[O.sub.2] (60.3 [+ or -] 17.6 vs. 84.5 [+ or -] 18.1 s; P < 0.001) and [V.sub.E] (59.4 [+ or -] 16.1 vs. 85.9 [+ or -] 17.1 s; P < 0.001). The average rise in [tau] was 41.3% for [V.sub.[O.sub.2]] 40.1% for [V.sub.[C[O.sub.2]], and 44.6% for [V.sub.E]. The 'r changes indicated that neuromechanical ventilatory factors play a role in the ventilatory response to moderate exercise. neuromechanical ventilatory factors more...

Published
2005

28. Reproducibility of Real-Time Shear Wave Ultrasound Elastography, A New Tool for the Evaluation of Diaphragm and Limb Muscles Stiffness in Critically Ill Patients: Preliminary Results of the Ultramuscle Study

Author

Jung, B., primary, Aarab, Y., additional, Flatres, A., additional, Amalric, M., additional, Tudesq, J.-J., additional, Larcher, R., additional, Chapeau, D., additional, Jaber, S., additional, Klouche, K., additional, and Matecki, S., additional more...

Published
2019
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30. Cardiopulmonary fitness in children with congenital heart diseases versus healthy children: A multicenter cross-sectional study

Author

Rola, M., primary, Gavotto, A., additional, Guillaumont, S., additional, Vincenti, M., additional, Bredy, C., additional, De La Villeon, G., additional, Picot, M.C., additional, Bertet, H., additional, Vandenberghe, D., additional, Werner, O., additional, Ovaert, C., additional, Acar, P., additional, Matecki, S., additional, and Amedro, P., additional more...

Published
2018
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31. Does training respiratory physicians in clinical respiratory physiology and interpretation of pulmonary function tests improve core knowledge?

Author

Patout, M, primary, Sesé, L, additional, Gille, T, additional, Coiffard, B, additional, Korzeniewski, S, additional, Lhuillier, E, additional, Pradel, A, additional, Tardif, C, additional, Chambellan, A, additional, Straus, C, additional, Matecki, S, additional, Perez, T, additional, Thiberville, L, additional, and Didier, A, additional more...

Published
2017
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32. Mise en évidence d’un défaut de recrutement du lit capillaire pulmonaire par méthode de double transfert NO/CO chez le patient atteint d’hypertension artérielle pulmonaire

Author

Mane, J., primary, Boissin, C., additional, Bughin, F., additional, Ayoub, B., additional, Suc, A., additional, Caule, S., additional, Mazars, A., additional, Lopez, N., additional, Bacon, L., additional, Matecki, S., additional, Mercier, J., additional, Bourdin, A., additional, Hayot, M., additional, and Gouzi, F., additional more...

Published
2017
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34. Corrélation entre VO2 et qualité de vie chez l’enfant cardiaque

Author

Amedro, P., primary, Picot, M.C., additional, Stéphane, M., additional, Dorka, R., additional, Bertet, H., additional, Guillaumont, S., additional, Barrea, C., additional, Vincenti, M.-C., additional, De la Villeon, G., additional, Bredy, C., additional, Soulatges, C., additional, Voisin, M., additional, Matecki, S., additional, and Auquier, P., additional more...

Published
2016
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37. Enquête sur la physiologie respiratoire et les internes en pneumologie

Author

Patout, M., primary, Coiffard, B., additional, Sésé, L.-C., additional, Korzeniewski, S., additional, Bunel, V., additional, Luchez, A., additional, Desseigne, M., additional, Emery, M., additional, Lhuillier, E., additional, Salvator, H., additional, Matecki, S., additional, Perez, T., additional, Chambellan, A., additional, De Jesus, A.-M., additional, Gille, T., additional, Tardif, C., additional, Pradel, A.-F., additional, Straus, C., additional, Thiberville, L., additional, and Didier, A., additional more...

Published
2015
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39. Targeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor

Author

Chauvier, D, primary, Renolleau, S, additional, Holifanjaniaina, S, additional, Ankri, S, additional, Bezault, M, additional, Schwendimann, L, additional, Rousset, C, additional, Casimir, R, additional, Hoebeke, J, additional, Smirnova, M, additional, Debret, G, additional, Trichet, A-P, additional, Carlsson, Y, additional, Wang, X, additional, Bernard, E, additional, Hébert, M, additional, Rauzier, J-M, additional, Matecki, S, additional, Lacampagne, A, additional, Rustin, P, additional, Mariani, J, additional, Hagberg, H, additional, Gressens, P, additional, Charriaut-Marlangue, C, additional, and Jacotot, E, additional more...

Published
2011
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49. Neurally adjusted ventilatory assist vs pressure support ventilation for noninvasive ventilation during acute respiratory failure: a crossover physiologic study.

Author

Bertrand PM, Futier E, Coisel Y, Matecki S, Jaber S, Constantin JM, Bertrand, Pierre-Marie, Futier, Emmanuel, Coisel, Yannael, Matecki, Stefan, Jaber, Samir, and Constantin, Jean-Michel

Abstract

Background: Patient-ventilator asynchrony is common during noninvasive ventilation (NIV) with pressure support ventilation (PSV). We examined the effect of neurally adjusted ventilatory assist (NAVA) delivered through a facemask on synchronization in patients with acute respiratory failure (ARF).Methods: This was a prospective, physiologic, crossover study of 13 patients with ARF (median Pa(O(2))/F(IO(2)), 196 [interquartile range (IQR), 142-225]) given two 30-min trials of NIV with PSV and NAVA in random order. Diaphragm electrical activity (EAdi), neural inspiratory time (T(In)), trigger delay (Td), asynchrony index (AI), arterial blood gas levels, and patient discomfort were recorded.Results: There were significantly fewer asynchrony events during NAVA than during PSV (10 [IQR, 5-14] events vs 17 [IQR, 8-24] events, P = .017), and the occurrence of severe asynchrony (AI > 10%) was also less under NAVA (P = .027). Ineffective efforts and delayed cycling were significantly less with NAVA (P < .05 for both). NAVA was also associated with reduced Td (0 [IQR, 0-30] milliseconds vs 90 [IQR, 30-130] milliseconds, P < .001) and inspiratory time in excess (10 [IQR, 0-28] milliseconds vs 125 [IQR, 20-312] milliseconds, P < .001), but T(In) was similar under PSV and NAVA. The EAdi signal to its maximal value was higher during NAVA than during PSV ( P = .017). There were no significant differences in arterial blood gases or patient discomfort under PSV and NAVA.Conclusion: In view of specific experimental conditions, our comparison of PSV and NAVA indicated that NAVA significantly reduced severe patient-ventilator asynchrony and resulted in similar improvements in gas exchange during NIV for ARF.Trial Registry: ClinicalTrials.gov; No.: NCT01426178; URL: www.clinicaltrials.gov. [ABSTRACT FROM AUTHOR] more...

Published
2013
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