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Abstract Future wireless communication systems at low terahertz frequencies (0.1–1 THz) suffer from high attenuation losses, and therefore, highly directive antennas are foreseen. As highly directive antennas have narrow beams, the alignment of the transmitter and the receiver is a crucial step in such systems. A device discovery approach using results from ray tracing (RT) combined with an iterative fine tuning is presented by the authors. A summary of previous investigations emphasises the benefits in terms of performance compared to an iterative approach. Furthermore, it indicates strong dependency of the RT output on the accuracy of the input data, that is, the environmental model. The authors extend the previous works by evaluating the impact of antenna characteristics. It is shown that the sidelobes lead to an error in the final alignment due to the superposition of the received power via multipath components, and equations to calculate the maximum error are given. Besides, the impact is evaluated with respect to sidelobe suppression. Here, equations to calculate the maximum error are given and it is shown that the sidelobes do not affect the alignment if the gain of the sidelobe is more than 30 dB lower than that of the mainlobe.

Vehicle-to-vehicle (V2V) channels exhibit unique properties due to the highly dynamic environment and low elevation of the antennas at both ends of the link. Of particular importance for the behavior of V2V channels, and consequent reliability of the communication link, is the severity and dynamics of blockage of both the line-of-sight and other multipath components (MPCs). The characteristics of blockage become more important as the carrier frequency increases, and the ability of the signal to penetrate through objects diminishes. To characterize the effects of vehicle blockage, we performed V2V channel measurements in four different frequency bands (6.75, 30, 60, and 73 GHz) in urban and highway scenarios. We analyzed the impact of the blocker size and position on the received power and fast fading parameters, as well as the frequency dependence of these parameters under blockage. Our results show that there is a strong influence of the size of the blocking vehicle on the blockage loss and the angular/delay spread. The position of the blocker relative to the transmitter and receiver also plays an important role. On the other hand, the frequency dependence is quite limited, with the blockage loss increasing slightly and the number of scattered MPCs reducing slightly as frequency increases. The main conclusion of this paper is that V2V communication will be possible in high (millimeter-wave) frequencies, even in the case of blockage by other vehicles.

Recent research has shown that both radio and visible light waves can be used to enable communications in highly dynamic vehicular environments. However, the roles of these two technologies and how they interact with each other in future vehicular communication systems remain unclear. Understanding the propagation characteristics is an essential step in investigating the benefits and shortcomings of each technology. To this end, we discuss salient properties of radio and visible light propagation channels, including radiation pattern, path loss modeling, noise and interference, and channel time variation. Comparison of these properties provides an important insight that the two communication channels can complement each other's capabilities in terms of coverage and reliability, thus better satisfying the diverse requirements of future cooperative intelligent transportation systems.

Abstract Background In countries with elevated prevalence of zoonotic anisakiasis and high awareness of this parasitosis, a considerable number of cases that associate Anisakis sp. (Nematoda, Anisakidae) and different bowel carcinomas have been described. Although neoplasia and embedded larvae were observed sharing the common site affected by chronic inflammation, no association between the nematode and malignancy were directly proved. Similarly, no data are available about the effect of secretory and excretory products of infecting larvae at the host’s cellular level, except in respect to allergenic interaction. Methods To test the mechanisms by which human non-immune cells respond to the larvae, we exposed the fibroblast cell line HS-68 to two Anisakis products (ES, excretory/secretory products; and EC, crude extract) and evaluated molecular markers related to stress response, oxidative stress, inflammation and apoptosis, such as p53, HSP70, TNF-α, c-jun and c-fos, employing cell viability assay, spectrophotometry, immunoblotting and qPCR. Results Both Anisakis products led to increased production of reactive oxygen species (ROS), especially in EC-treated cells. While the ES treatment induces activation of kinases suggesting inflammation and cell proliferation (or inhibition of apoptosis), in EC-treated cells, other signaling pathways indicate the inhibition of apoptosis, marked by strong upregulation of Hsp70. Elevated induction of p53 in fibroblasts treated by both Anisakis products, suggests a significantly negative effect on the host DNA. Conclusions This study shows that in vitro cell response to Anisakis products can result in at least two different scenarios, which in both cases lead to inflammation and DNA damage. Although these preliminary results are far from proving a relationship between the parasite and cancer, they are the first to support the existence of conditions where such changes are feasible.

Future 5G systems have set a goal to support mission-critical Vehicle-to-Everything (V2X) communications and they contribute to an important step towards connected and automated driving. To achieve this goal, the communication technologies should be designed based on a solid understanding of the new V2X applications and the related requirements and challenges. In this regard, we provide a description of the main V2X application categories and their representative use cases selected based on an analysis of the future needs of cooperative and automated driving. We also present a methodology on how to derive the network related requirements from the automotive specific requirements. The methodology can be used to analyze the key requirements of both existing and future V2X use cases.