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The aim of this study was to investigate the effect of a behaviour intervention for child sleep problems on the mother's internalizing behaviour. Sixty-two mothers who participated in an intervention for childhood insomnia through a programme designed for parents were evaluated using the Adult Self Report. Assessments were conducted one week before and one week after treatment completion. The child sleep problem score and mother internalizing behaviour score were significantly lower after the treatment of child sleep problems when compared to the pre-treatment period. However, adjusted analyses demonstrated that only maternal adaptive functioning continued to exert a significant and independent effect on the mother's internalizing behaviour even after adjustment for maternal age and child sleep problems ([beta] = -0.518; p < 0.01). The current study demonstrated that a behavioural intervention for improving child sleep problems through a programme designed for parents also benefited the mother's internalizing behaviour.

We examined the association of maternal depression and anxiety symptoms with the weight status of children at preschool age. The current study is a cross-sectional study, which was carried out in the homes of the participants between July 2016 and August 2017. Maternal depression and anxiety symptoms were assessed using the Beck Depression Inventory-II and the Beck Anxiety Inventory, respectively. Of the 216 children included in the study, 69.4%, 21.3% and 9.3% were classified as [less than or equal to]85th, >85th and <97th and >85th percentile, respectively. The prevalence of moderate/severe maternal depression and anxiety symptoms was 20.1% and 19.5%, respectively. Children whose mothers had moderate/severe symptoms of depression and minimal/mild symptoms of anxiety were more likely to have excess body weight at preschool age than children whose mothers had both minimal/mild symptoms of depression and anxiety. We found that maternal depression symptoms are associated with excess body weight in children at preschool age.

Retinopathy of prematurity (ROP) is a leading cause of blindness in premature infants. The condition is associated with DHA deficiency. This study aimed to investigate the effect of DHA supplementation on the occurrence of ROP in infants receiving oral oil drops. It is part of the Joinville DHA study, a non-parallel-group cohort study conducted from March 2020 to January 2023 at a public maternity hospital in Brazil. Infants born before 33 weeks of gestational age or with a birth weight ≤ 1500 g were recruited. Among 155 infants, 81 did not receive and 74 received DHA supplementation until complete vascularisation of the peripheral retina. There was a higher incidence of infants with ROP in the unsupplemented group (58·6 %) compared with the DHA group (41·4 %), but this difference was NS (P  = 0·22). Unadjusted logistic regression analysis showed that patent ductus arteriosus and neonatal corticosteroids were significantly (P  < 0·05) associated with ROP in both groups. In the DHA group, surfactant use was also associated with ROP (P  = 0·003). After adjusting for important covariates, patent ductus arteriosus and neonatal corticosteroids continued to be significant for infants in the unsupplemented group (OR = 3·99; P  = 0·022 and OR = 5·64; P  = 0·019, respectively). In the DHA group, only surfactant use continued to be associated with ROP (OR = 4·84; P  = 0·015). In summary, DHA supplementation was not associated with ROP. Further studies are necessary to better understand the relationship between DHA supplementation, ROP and associated comorbidities. [ABSTRACT FROM AUTHOR]

The aim of this study was to investigate the effect of a behaviour intervention for child sleep problems on the mother's internalizing behaviour. Sixty-two mothers who participated in an intervention for childhood insomnia through a programme designed for parents were evaluated using the Adult Self Report. Assessments were conducted one week before and one week after treatment completion. The child sleep problem score and mother internalizing behaviour score were significantly lower after the treatment of child sleep problems when compared to the pre-treatment period. However, adjusted analyses demonstrated that only maternal adaptive functioning continued to exert a significant and independent effect on the mother's internalizing behaviour even after adjustment for maternal age and child sleep problems (β = −0.518; p < 0.01). The current study demonstrated that a behavioural intervention for improving child sleep problems through a programme designed for parents also benefited the mother's internalizing behaviour. [ABSTRACT FROM AUTHOR]

Excess body weight confers a high risk to human health. Body weight variation between subjects can be partially explained by genetic differences. The aim of the present study was to investigate the association of genetic variants in the ADIPOQ (rs2241766) and LEP (rs7799039) genes with body weight trajectories in children from birth to 6 years of age. This was a prospective cohort (PREDI Study). Socio-economic, biological and anthropometric data were collected at four time points: at birth in the maternity unit; 1–2, 4–5 and 6 years old at the participants' homes. Genotyping was performed by PCR-restriction fragment length polymorphism. Poisson regression and linear mixed-effect regression models were used to address the association of ADIPOQ and LEP genotypes with BMI. Excessive body weight at pre-pregnancy (β = 0·339, P = 0·01) and excessive gestational weight gain (β = 0·51, P < 0·001) were associated with children's BMI trajectory from birth to 6 years. The ADIPOQ-rs2241766 TG or GG genotype was associated with a higher risk of excess body weight in the first 6 years of life (both sexes relative risk 1·25, 95 % CI 1·01, 1·56; female relative risk 1·67, 95 % CI 1·20, 2·31). BMI increased over the years according to the presence of the TG or GG genotype (β = 0·01, 95 % CI 0·01, 0·02), particularly in females (β = 0·02, 95 % CI 0·01, 0·04). The ADIPOQ-rs2241766 TG and GG genotypes increased the risk of excess body weight in children from birth to 6 years of age and had a positive effect on body weight trajectories in girls. The LEP-rs7799039 genetic variant was not associated with body weight trajectory in children. [ABSTRACT FROM AUTHOR]

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Copyright of Brazilian Journal of Mother & Child Health (BJMCH) / Revista Brasileira de Saude Materno Infantil (RBSMI) is the property of Instituto de Medicina Integral and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To describe the demographic and clinical characteristics of patients undergoing coronary artery bypass graft surgery (CABG) and to test their relation to mortality. Methods: This study was a retrospective medical record review of 655 consecutive patients undergoing CABG from May 2002 to April 2010. Results: Of the 655 patients, 12.1% died during the hospital stay. Mortality was significantly (p<0.05) higher in females (17.3%), aged <70 years (22.8%), in emergency surgery (36.4%), in cases of readmission to the intensive care unit (ICU) (33.3%), when the stay in the ICU was < three days (16.3%), undergoing longer cardiopulmonary bypass (CPB), and with more comorbidities (15.4%). Predictor variables of death identified with logistical regression analysis were: female (OR=2.04), age > 70 years (OR=2.69), emergency surgery (OR=15.43) and urgency (OR=3.81), performance of CPB (OR=2.19) and readmission to the ICU (OR=4.33). Conclusion: Variables such as female sex, increased age, type of surgery, readmission to the ICU, ICU stay, comorbidities, and duration of CPB influence the outcome death in patients undergoing CABG. Thus, such aspects should be considered to reduce hospital mortality in patients undergoing such surgery. Objetivo: Descrever as características clínicodemográficas e testar sua relação com a mortalidade hospitalar em pacientes submetidos à cirurgia de revascularização do miocárdio (CRM). Métodos: Estudo retrospectivo conduzido a partir dos prontuários de 655 pacientes submetidos à CRM, no período de maio de 2002 a abril de 2010. Resultados: A mortalidade hospitalar foi de 12,1%. A mortalidade foi significativamente (P<0,05) maior em indivíduos do sexo feminino (17,3%), com idade igual ou superior a 70 anos (22,8%), em cirurgias de emergência (36,4%), nos casos de reinternação na unidade de terapia intensiva (UTI) (33,3%), quando a permanência foi inferior a três dias na UTI (16,3%), submetidos a maior tempo de circulação extracorpórea (CEC) e com maior número de comorbidades (15,4%). As variáveis preditoras de óbito identificadas pela análise de regressão logística foram: sexo feminino (OR=2,04); idade ≥ 70 anos (OR=2,69); cirurgias em caráter de emergência (OR=15,43) e de urgência (OR=3,81); realização de CEC (OR=2,19) e reinternação na UTI (OR=4,33). Conclusão: Sexo, idade, tipo de cirurgia, reinternação na UTI, permanência na UTI, comorbidades e tempo de CEC influenciaram no desfecho óbito do paciente submetido à CRM. Dessa forma, tais aspectos devem ser considerados para diminuir o óbito hospitalar em pacientes submetidos a esse tipo de cirurgia. [ABSTRACT FROM AUTHOR]

Objective: The aim of this study was to examine the influence of the FTO‐rs9939609 polymorphism on excess body weight in women during the reproductive transition from pre‐ to post‐pregnancy. Methods: This was a prospective cohort study covering a period extending from before pregnancy to 2 and 4 years after pregnancy. A total of 435 women were first included in the study and, at last follow‐up, 220 of them continued to participate in the study. The FTO‐rs9939609 polymorphism was analyzed by the polymerase chain reaction/ restriction fragment length polymorphism (PCR/RFLP) method. Results: The FTO‐rs9939609 polymorphism was associated with increasing weight and body mass index (BMI) during the follow‐up period. Women carrying at least 1 risk allele (A) were significantly heavier (P <.05, up to 4.24 kg) and had a 1.30 kg/m2 higher BMI. Although the AA genotype was significantly associated with a greater risk compared to the wild‐type genotype in the cross‐sectional analysis, the results did not differ significantly in the longitudinal analysis (AA genotype, β = 1.20, 95% CI 0.85‐1.68), even after adjustment for pre‐pregnancy age, smoking before pregnancy, parity at pregnancy, and gestational weight gain. Conclusions: The FTO‐rs9939609 polymorphism was associated with increased weight and BMI in mothers before and after pregnancy. However, we found no significant effect of the polymorphism on excess body weight of women during the reproductive trajectory. [ABSTRACT FROM AUTHOR]

This study aimed to analyze the effect of type of breastfeeding on the nutritional status of children between 12-24 months of age. This cohort study included 435 children born in 2012 in a public hospital in Joinville, Santa Catarina State, Brazil. Two years after delivery the mothers and their children were contacted in their homes for a new investigation of demographic, economic, nutritional, and anthropometric data. In the unadjusted analysis, children who were not exclusively breastfed were more likely to be overweight (including obesity) at 2 years of age (OR = 1.6; p = 0.049) than exclusively breastfed children. After adjusting for several covariates, children who were not exclusively breastfed had a 12% higher risk of overweight including obesity compared to unadjusted analysis (OR = 2.6 vs. OR = 1.8; p = 0.043). In addition, birthweight was also an independent determinant of overweight including obesity (OR = 2.5; p = 0.002). The practice of exclusive breastfeeding can reduce the risk of overweight in children from developing countries such as Brazil.

Objective: Describe the impact of severe sepsis and septic shock on patients' quality of life following hospital discharge., Methods: A controlled study conducted in two general hospitals of Joinville, Santa Catarina, Brazil, of in-patients with severe sepsis or septic shock during the period of August 2005 through November 2007. The patients were contacted by telephone between June and November 2009. The study group responded to Short Form-36, a questionnaire on the quality of life, two years after being discharged from hospital. The questionnaire was also answered by a control group composed of people who lived at the same residence as the study subjects, had no recent hospitalization, and were close in age., Results: Of 217 patients with severe sepsis or septic shock, 112 (51.6%) survived hospitalization. The survival rate after hospital discharge was 41.02% at 180 days, 37.4% at one year, 34.3% at 18 months, and 32.3% in two years. Thirty-six survivors responded to Short Form-36. There were declines in the quality of life for survivors (No. = 36) in comparison to the control group (No. = 36) in the following areas: physical functioning (59 ± 32 versus 91 ± 18; P < 0.001), vitality (48 ± 13 versus 59 ± 14; P < 0.008), mental health (48 ± 13 versus 59 ± 14; P < 0.03), bodily pain (50 ± 26 versus 76 ± 16; P < 0.001), general health perceptions (53 ± 18 versus 67 ± 13; P < 0.004), physical role functioning (67 ± 45 versus 85 ± 34; P < 0.05), and social role functioning (70 ± 28 versus 90. ± 16; P < 0.05)., Conclusions: Severe sepsis or septic shock can result in significant negative effects on the quality of life, in addition to reducing long-term survival probability.

Objective: To describe the demographic and clinical characteristics and to test their relation to mortality in patients undergoing to coronary artery bypass graft surgery (CABG)., Methods: It is a retrospective study developed from the medical records of 655 patients undergoing CABG from May 2002 to April 2010., Results: Hospital mortality was 12.1%. Mortality was significantly (P<0.05) higher in females (17.3%), aged less than 70 years (22.8%), in emergency surgery (36.4%), in cases of readmission to the intensive care unit (ICU) (33.3%), when the stay in the ICU was less than three days (16.3%), undergoing longer cardiopulmonary bypass (CPB) and with more comorbidities (15.4%). Predictor variables of death identified with logistic regression analysis were: female (OR=2.04), age >70 years (OR=2.69), emergency surgery (OR=15.43) and urgency (OR=3.81), performance of CPB (OR=2.19) and re-admission to the ICU (OR=4.33)., Conclusion: Variables such as gender, age, type of surgery, readmission to the ICU, ICU stay, comorbidities and time of CPB influence the outcome death in patients undergoing to CABG. Thus, such aspects should be considered to reduce hospital mortality in patients undergoing such surgery.