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4. Clinical and economic outcomes of infective endocarditis

Author

Sunder, Simon, primary, Grammatico-Guillon, Leslie, additional, Baron, Sabine, additional, Gaborit, Christophe, additional, Bernard-Brunet, Anne, additional, Garot, Denis, additional, Legras, Annick, additional, Prazuck, Thierry, additional, Dibon, Olivier, additional, Boulain, Thierry, additional, Tabone, Xavier, additional, Guimard, Yves, additional, Massot, Michel, additional, Valery, Antoine, additional, Rusch, Emmanuel, additional, and Bernard, Louis, additional

Published
2014
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7. Clinical and economic outcomes of infective endocarditis.

Author

Sunder, Simon, Grammatico-Guillon, Leslie, Baron, Sabine, Gaborit, Christophe, Bernard-Brunet, Anne, Garot, Denis, Legras, Annick, Prazuck, Thierry, Dibon, Olivier, Boulain, Thierry, Tabone, Xavier, Guimard, Yves, Massot, Michel, Valery, Antoine, Rusch, Emmanuel, and Bernard, Louis

Subjects
INFECTIVE endocarditis, HEART valve surgery, MEDICAL care costs, INTENSIVE care units, HOSPITAL admission & discharge, EPIDEMIOLOGY, GRAM-negative bacteria, THERAPEUTICS, CHI-squared test, CONFIDENCE intervals, FISHER exact test, LENGTH of stay in hospitals, RESEARCH methodology, MULTIVARIATE analysis, STATISTICAL sampling, T-test (Statistics), LOGISTIC regression analysis, RELATIVE medical risk, PREDICTIVE tests, DATA analysis software, DESCRIPTIVE statistics, HOSPITAL mortality, ODDS ratio, MANN Whitney U Test, DISEASE complications
Abstract

Background: In France, the estimated annual incidence of infective endocarditis (IE) is 33.8 cases per million residents. Valvular surgery is frequently undergone. We report an epidemiological and economic study of IE for 2007 - 2009 in a French region, using the hospital discharge database (HDD). Methods: The population studied concerned all the patients living in Centre region, France, hospitalized for IE. We extracted hospital stay data for IE from the regional HDD, with a definition based on IE-related diagnosis codes. The predictive positive value (PPV) and sensitivity (Se) of the definition were 87.4% and 90%, respectively, according to the Duke criteria (definite IE frequency 74.4%). Hospitalization costs were estimated, taking into account the fi xed hospital charges of the diagnosis-related group (DRG) and supplementary charges due to intensive care unit (ICU) stay. Results: The analysis included 578 patients. The annual average incidence was 45.4 cases per million residents. Valvular surgery was performed in 19.4% of cases. The hospital mortality was 17.6%. Multivariate analysis identified as risk factors for mortality an age ≥ 70 years (odds ratio (OR) = 3.03, 95% confidence interval (CI) = 1.78 - 5.18), staphylococcal IE (OR = 3.3, 95% CI = 1.9 - 5.7), chronic renal insufficiency (OR = 2.04, 95% CI = 1.00 - 4.15), ischemic stroke (OR = 2.55, 95% CI = 1.19 - 5.47), and hemorrhagic stroke (OR = 5.7, 95% CI = 1.9 - 17.3). The average cost per episode was $20 103 (€ 15 281). Conclusions: We report a higher incidence of IE than described by the French national study of 2008. Valvular surgery was considerably less frequent than in the published data, whereas mortality was similar. IE generates substantial costs. [ABSTRACT FROM AUTHOR]

Published
2015
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10. Synthesis, Structure and Electrochemical Properties of LiNi0.33Mn0.33Co0.33O2 Positive Electrode for Rechargeable Lithium Batteries

Author

Abdel, Ashraf, Mauger, Alain, Massot, Michel, Gendron, Francois, and Ramana, Chintalapalle V.

Abstract

The layered LiNi0.33Mn0.33Co0.33O2 materials were prepared by wet chemical method using oxalic acid as a polymeric agent. The positive LiNi0.33Mn0.33Co0.33O2 powders were characterized by means of X-ray diffraction, scanning electron microscopy, Raman spectroscopy, and magnetometry. Electrochemical features of LiNi0.33Mn0.33Co0.33O2 positive electrodes were investigated as a function of synthesis conditions, cutoff voltage limit, and C-rate discharge current. Electrochemical properties are discussed in relation with the local structure and morphology of the layered materials.

Published
2007

11. Epidémiologie des urgences ophtalmologiques dans un centre hospitalier non universitaire: spécificités cliniques et sévérité selon le Base Score

Author

Bigoteau, Maxime, Massot, Michel, Baudet, Jean-Marie, Pasco, Jeremy, Pichard, Tiphanie, Slim, Malek, Bourges, Jean-Louis, Pisella, Pierre-Jean, and Khanna, Raoul Kanav

Abstract

Objectif: L’objectif de cette étude était d’analyser les caractéristiques épidémiologiques des urgences ophtalmologiques du Centre Hospitalier de Bourges (CHB) et d’identifier les critères associés à un score de sévérité élevé en contexte d’offre de soin déficitaire.

Published
2021
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