39 results on '"Massimo Cristaldi"'
Search Results
2. Dal rilievo topografico alla rappresentazione virtuale
- Author
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Massimo Cristaldi, Primo Furno, and Marina Galeazzi
- Subjects
rilievo ,rilievo topografico ,3D ,2D ,rappresentazione virtuale ,Cartography ,GA101-1776 ,Cadastral mapping ,GA109.5 - Abstract
Le applicazioni 3D danno la possibilita di lavorare direttamente con il volume dei corpi solidi nello spazio geometrico a tre dimensioni, quale metafora della realtà. Quando la rappresentazione virtuale della realtà è costruita partendo da dati accurati derivanti dalla sua discretizzazione, come i dati rilevati durante una campagna di rilevamento, e dalla riproduzione fedele dei progetti tecnici 2D, il modello tridimensionale assume un'elevata efficacia, sia comunicativa che tecnico-progettuale. Con queste premesse, la rappresentazione assurge ad avere una valenza scientifica e diviene un utile strumento per i professionisti che hanno la necessita di dare "vita tridimensionale" alle idee, ai progetti ed ai prototipi, che possono essere realizzati virtualmente prima ancora che diventino realizzazioni reali. Accomunati dagli stessi intenti e condividendo la stessa vision, la MESTOR e l'Assessorato ai LL. PP del Comune di Catania, hanno avviato una proficua collaborazione, coordinata dal 4° Servizio "Progettazione e Realizzazione Nuovo Verde e Arredo Urbano" della V Direzione LL.PP, che ha portato alia modellazione e rendering del piu famoso giardino di Catania, nell'ambito degli interventi di "Recupero e Valorizzazione del Verde Storico Giardino Bellini".
- Published
- 2004
3. Web-Based Tool to Facilitate Resilience-Related Information Management.
- Author
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Hoang Long Nguyen 0001, Salvatore Antonio Marchese, Valentino Gandolfo, Leonardo Luca Trombetta, Massimo Cristaldi, Uberto Delprato, and Rajendra Akerkar
- Published
- 2022
- Full Text
- View/download PDF
4. Web-Based Tool to Facilitate Resilience-Related Information Management
- Author
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Hoang Long Nguyen, Salvatore Antonio Marchese, Valentino Gandolfo, Leonardo Luca Trombetta, Massimo Cristaldi, Uberto Delprato, and Rajendra Akerkar
- Published
- 2023
5. The Emergent Project: Emergency Management in Social Media Generation Dealing with Big Data from Social Media Data Streams.
- Author
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Reynold Greenlaw, Andrew Muddiman, Therese Friberg, Matthias Moi, Massimo Cristaldi, Thomas Ludwig 0005, and Christian Reuter 0001
- Published
- 2014
- Full Text
- View/download PDF
6. ITALSCAR, a regional burned forest mapping demonstration project in Italy.
- Author
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Marc Paganini, Olivier Arino, Marco Benvenuti, Massimo Cristaldi, Marco Bordin, Carlo Coretti, and Andrea Musone
- Published
- 2003
- Full Text
- View/download PDF
7. Rectosigmoid resection during Visceral-Peritoneal Debulking (VPD) in patients with stage IIIC-IV ovarian cancer: morbidity of gynecologic oncology vs. colorectal team
- Author
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Roberto, Tozzi, Gaetano, Valenti, Daniele, Vinti, Riccardo Garruto Campanile, Massimo, Cristaldi, and Ferrari, F
- Published
- 2021
8. Rectosigmoid resection by gynecologic oncologists versus colorectal surgeons: as long as it catches the mouse, does the color of the cat matter?
- Author
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Federico Ferrari, Roberto Tozzi, Massimo Cristaldi, Riccardo Garruto Campanile, Gaetano Valenti, and Daniele Vinti
- Subjects
medicine.medical_specialty ,Genital Neoplasms, Female ,MEDLINE ,Gynecologic oncology ,Anastomosis ,03 medical and health sciences ,Mice ,0302 clinical medicine ,medicine ,Animals ,Humans ,Stage IIIC ,Rectosigmoid resection ,Stage (cooking) ,Neoplasm Staging ,Oncologists ,Surgeons ,Ovarian Neoplasms ,030219 obstetrics & reproductive medicine ,business.industry ,Mortality rate ,General surgery ,Ovary ,Obstetrics and Gynecology ,General Medicine ,Cytoreduction Surgical Procedures ,Debulking ,medicine.disease ,Surgery ,Ovarian Cancer ,Editorial ,Oncology ,030220 oncology & carcinogenesis ,Cats ,Original Article ,Female ,Morbidity ,Colorectal Neoplasms ,Genital Neoplasms ,Ovarian cancer ,business ,Gynecologic Oncologist ,Colorectal surgeons - Abstract
Objective This study investigates the specific morbidity of rectosigmoid resection (RSR) during Visceral-Peritoneal Debulking (VPD) in a consecutive series of patients with stage IIIC-IV ovarian cancer and compares the results of the colo-rectal vs. the gynaecologic oncology team. Methods All patients with the International Federation of Gynecology and Obstetrics (FIGO) stage IIIC–IV ovarian cancer who had VPD and RSR were included in the study. Between 2009 and 2013 all operations were performed by the gynecologic oncology team alone (group 1). Since 2013 the RSR was performed by the colorectal team together with the gynecologic oncologist (group 2). All pre-operative information and surgical details were compared to exclude significant bias. Intra- and post-operative morbidity events were recorded and compared between groups. Results One hundred and sixty-two patients had a RSR during VPD, 93 in group 1 and 69 in group 2. Groups were comparable for all pre-operative features other than: albumin (12). Overall morbidity was 33% vs. 40% (p=0.53), bowel specific morbidity 11.8% vs. 11.5% (p=0.81), anastomotic leak 4.1% vs. 6.1% (p=0.43) and re-operation rate 9.6% vs. 6.1% (p=0.71) in groups 1 and 2, respectively. None of them were significantly different. The rate of bowel diversion was 36.5% in group 1 vs. 46.3% in group 2 (p=0.26). Conclusions Our study failed to demonstrate any significant difference in the morbidity rate of RSR based on the team performing the surgery. These data warrant further investigation as they are interesting with regards to education, finance, and medico-legal aspects.
- Published
- 2021
9. The Emergent Project: Emergency Management in Social Media Generation Dealing with Big Data from Social Media Data Streams
- Author
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Matthias Moi, Therese Friberg, Reynold Greenlaw, Thomas Ludwig, Massimo Cristaldi, Christian Reuter, and Andrew Muddiman
- Subjects
Knowledge management ,Emergency management ,business.industry ,Computer science ,Data stream mining ,Scale (social sciences) ,Big data ,Internet privacy ,Information quality ,Cloud computing ,Social media ,business ,Semantic Web - Abstract
The Emergent project will use social media to support the management of large scale emergencies. The project includes the construction of a big online store of data which will be continuously mined to provide emergency information and alerts. The overall objective is a stronger connection between citizens and emergency management authorities through social media.
- Published
- 2014
10. A prospective, longitudinal study of nonconventional strictureplasty in Crohn’s disease1
- Author
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F. Parente, Giovanni Maconi, Angelo Maria Taschieri, Piergiorgio Danelli, Massimo Cristaldi, Gianluca M. Sampietro, Sandro Ardizzone, A. Sartani, and Gabriele Bianchi Porro
- Subjects
Longitudinal study ,Crohn's disease ,medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Clinical course ,Perioperative ,Surgical procedures ,medicine.disease ,Surgery ,Resection ,Strictureplasty ,Medicine ,In patient ,business - Abstract
Background Bowel-sparing techniques have been proposed to avoid extended or repeated resections in patients with Crohn's disease (CD), but without precise indications, prospective evaluation, and with a technically limited repertoire. Study design A prospective longitudinal study of new nonconventional strictureplasties (NCSP) in order to evaluate the safety, type and site of recurrence, and longterm clinical and surgical efficacy. Results Between January 1993 and December 2002, 102 among 305 consecutive patients underwent at least one NCSP for complicated CD. Patients were treated following precise indications and then included in a prospective database with scheduled followup. Factors claimed to influence postoperative and longterm outcomes and type and site of recurrence were analyzed. We performed 48 ileoileal side-to-side isoperistaltic strictureplasty (SP), 41 widening ileocolic SP, 32 ileocolic side-to-side isoperistaltic SP, associated with Heineke-Mikulicz SP (in 80 procedures) or with minimal bowel resections or both (in 47 procedures). Postoperative mortality was nil; complication rate was 5.7%. Ten years clinical and surgical recurrence rates were 43% and 27%, respectively. Recurrence rate on an NCSP site was 0.8%. No specific factor was identified as related to postoperative or longterm outcomes. Conclusions Perioperative and longterm results of NCSP are comparable to or even better than both conservative and resective surgery as reported in the literature, with a low recurrence rate on the NCSP site. Considering the unpredictability of the clinical course of CD and the lifetime need for surgical procedures, NCSP, together with minimal resection and classic SP repertoire, should be considered first-line treatment in complicated CD.
- Published
- 2004
11. CASE REPORT: Ultrasonographic Detection of Toxic Megacolon in Inflammatory Bowel Diseases
- Author
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Piergiorgio Danelli, Massimo Cristaldi, Sandro Ardizzone, Gianluca M. Sampietro, Luca Carsana, Giovanni Maconi, and Gabriele Bianchi Porro
- Subjects
Crohn's disease ,medicine.medical_specialty ,Pathology ,Toxic megacolon ,Megacolon ,Physiology ,Crohn disease ,business.industry ,Gastroenterology ,Inflammatory Bowel Diseases ,Hepatology ,medicine.disease ,Ulcerative colitis ,Internal medicine ,medicine ,Differential diagnosis ,business - Published
- 2004
12. Role of early ultrasound in detecting inflammatory intestinal disorders and identifying their anatomical location within the bowel
- Author
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Giovanni Maconi, S. Greco, F. Parente, Massimo Cristaldi, M. Molteni, Roberto Bianco, G. Bianchi Porro, Claudia Cucino, Silvano Gallus, Giuseppe Sampietro, and Piergiorgio Danelli
- Subjects
medicine.medical_specialty ,Hepatology ,medicine.diagnostic_test ,business.industry ,digestive, oral, and skin physiology ,Ultrasound ,Gastroenterology ,Rectum ,Diverticulitis ,medicine.disease ,Ulcerative colitis ,digestive system diseases ,Appendicitis ,Descending colon ,Endoscopy ,medicine.anatomical_structure ,Internal medicine ,medicine ,Duodenum ,Pharmacology (medical) ,business - Abstract
Summary Background : Although bowel ultrasound is a widely accepted diagnostic tool in bowel diseases, its value as the primary imaging procedure in patients with symptoms/signs suggestive of inflammatory bowel disorders is still unclear. Aim : To investigate the accuracy of bowel ultrasound compared with barium X-ray studies, computed tomography, endoscopy and bowel surgery in the initial assessment of inflammatory bowel disorders. Methods : Four hundred and eighty-seven patients hospitalized consecutively for symptoms or signs suggestive of a bowel disorder between December 1999 and March 2002 were initially enrolled in the study. All patients underwent bowel ultrasound as the first imaging procedure within 36 h of admission; radiographic evaluations, endoscopy and/or surgery were then performed as appropriate and the results of these investigations were used as the gold standard. Results : Three hundred and thirty-six patients had pathological findings of the bowel detectable at ultrasound as the final diagnosis. The main organic disorders found were Crohn's disease (56%), ulcerative/indeterminate colitis (30%), bowel tumours (5%), appendicitis/diverticulitis (2%) and other inflammatory conditions (8%). The overall sensitivity and specificity of bowel ultrasound were 85% and 95%, respectively, whereas the positive and negative predictive values were 98% and 75%, respectively. Comparisons of ultrasound with X-ray or endoscopic results by disease localization showed that the diagnostic performance of ultrasound was higher for inflammatory conditions of the ileum and sigmoid/descending colon (sensitivity of 92% and 87%, respectively), whereas abnormalities localized in the rectum, duodenum and proximal jejunum were often missed by ultrasound. Conclusions : In expert hands, bowel ultrasound is highly predictive of inflammatory disease localized in the ileum or colon, and may well be used as the primary imaging method when Crohn's disease or ulcerative colitis is suspected on a clinical basis.
- Published
- 2003
13. Small bowel stenosis in Crohn's disease: clinical, biochemical and ultrasonographic evaluation of histological features
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Giovanni Maconi, Massimo Cristaldi, Angelo Maria Taschieri, Giuseppe Sampietro, Gianluca Vago, Sandro Ardizzone, Paolo Fociani, Luca Carsana, F. Parente, and G. Bianchi Porro
- Subjects
Ileal stenosis ,medicine.medical_specialty ,Crohn's disease ,Hepatology ,business.industry ,Ultrasound ,Gastroenterology ,medicine.disease ,Stenosis ,Fibrosis ,Internal medicine ,Medicine ,Immunohistochemistry ,Pharmacology (medical) ,Negative correlation ,business ,Surgical treatment - Abstract
Summary Aim : To establish whether intestinal ultrasound, clinical or biochemical indices of activity can assess histological features of ileal stenosis in Crohn's disease. Methods : In 43 patients undergoing surgery for a single ileal stenosis, clinical and biochemical parameters, as well as intestinal ultrasound, were assessed prior to surgery. The echo pattern of thickened bowel segments at the site of stenosis was classified as hypoechoic, stratified or mixed (segments with/without stratification). During surgery, stenoses were identified, resected and then histologically examined using standardized criteria. Results : Clinical and biochemical indices of activity showed an overall weak positive correlation with histological inflammatory parameters and a negative correlation with fibrosis. The intestinal ultrasound echo pattern at the stenosis site was stratified in 25 patients, hypoechoic in 14 and mixed in four. Stenoses characterized by a stratified echo pattern showed a significantly higher degree of fibrosis, those characterized by hypoechoic echo pattern showed a higher degree of inflammation, while stenoses with a mixed echo pattern showed high degrees of both fibrosis and inflammation. Conclusion : Ultrasound and, to a lesser degree, clinical and laboratory indices discriminate between inflammatory and fibrotic ileal stenoses complicating Crohn's disease, thus allowing appropriate medical and/or surgical treatment to be defined.
- Published
- 2003
14. Gastric cancer in young patients with no alarm symptoms: focus on delay in diagnosis, stage of neoplasm and survival
- Author
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Giovanni Maconi, Angelo Maria Taschieri, Antonio Russo, Paolo Morgagni, Daniele Marrelli, V. Panizzo, G. De Manzoni, Paolo Bechi, F. Roviello, A. Di Leo, Hayato Kurihara, Massimo Cristaldi, and G. Bianchi Porro
- Subjects
Adult ,Male ,medicine.medical_specialty ,diagnosis ,Nausea ,survival ,Asymptomatic ,alarm symptoms ,Stomach Neoplasms ,Internal medicine ,Weight Loss ,medicine ,Humans ,Dyspepsia ,Young adult ,Retrospective Studies ,business.industry ,Stomach ,Age Factors ,Gastroenterology ,Heartburn ,Cancer ,Retrospective cohort study ,Middle Aged ,medicine.disease ,Surgery ,Survival Rate ,medicine.anatomical_structure ,Vomiting ,Female ,medicine.symptom ,Gastric cancer ,business - Abstract
The test and treat strategy for Helicobacter pylori infection has raised some concern since young gastric cancer patients may have no alarm symptoms. In this study the frequency of alarm symptoms was assessed in a series of young gastric cancer patients, as well as the impact of absence of alarm symptoms on delay in diagnosis and stage of gastric cancer at diagnosis and survival.A retrospective study was carried out on 92 gastric cancer patientsor = 45 years of age identified from databases in four hospitals between January 1985 and December 2001. Characteristics analysed included duration and features of dyspeptic symptoms, presence of alarm symptoms, time interval from the onset of symptoms to diagnosis, pTNM stage and survival.Of the 92 patients, 54 (58.7%) presented uncomplicated dyspepsia and 38 (41.3%) alarm symptoms. In those with uncomplicated dyspepsia, epigastric pain was the most common complaint (64.1%) followed by vomiting (30.4%), heartburn and nausea. Weight loss was the most common alarm symptom (30.4%), followed by anorexia (10.9%), dysphagia or anaemia (7.6%). The mean delay from first symptoms to final diagnosis was 16.8 +/- 13.9 weeks in patients with alarm symptoms and 29.3 +/- 39.9 weeks in patients without alarm symptoms (P:ns). Patients without alarm symptoms showed significantly less aggressive gastric cancer compared to patients with alarm symptoms in relation to TNM stage and survival (cumulative 5-year survival rate: 76% versus 49% P: 0.01). The survival rate, at 5 years, of patients without alarm symptoms, and with a history of dyspepsia of more than 24 weeks, was higher than that in patients with early diagnosis (93.4% versus 66.5%: P: 0.05).A large proportion of young gastric cancer patients present without alarm symptoms. Despite the delay in diagnosis, these patients have a better outcome than those with alarm symptoms. Thus the delay in diagnosis of patients without alarm symptoms does not affect survival.
- Published
- 2003
15. Laparoscopic-Assisted Endoscopic Sigmoidopexy: A New Surgical Option for Sigmoid Volvulus
- Author
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Massimo Cristaldi, Jeffrey Lim, Alex Gordon-Weeks, and Bruno Lorenzi
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medicine.medical_specialty ,Intraoperative Complication ,Percutaneous ,medicine.medical_treatment ,Abdominal wall ,Colon, Sigmoid ,medicine ,Humans ,Laparoscopy ,Colectomy ,Aged ,Retrospective Studies ,Aged, 80 and over ,Sigmoid Diseases ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Colostomy ,General Medicine ,medicine.disease ,digestive system diseases ,Surgery ,Volvulus ,Endoscopy ,Treatment Outcome ,medicine.anatomical_structure ,business ,Follow-Up Studies ,Intestinal Volvulus - Abstract
OBJECTIVES: Sigmoid volvulus accounts for 5% of cases of large-bowel obstruction. Here, we present the development of a new minimally invasive treatment method that aims to reduce the complication rate of standard percutaneous endoscopic colostomy tube insertion and negate the need for prolonged anesthesia or colectomy. METHODS: Six patients underwent laparoscopic-assisted endoscopic sigmoidopexy for recurrent sigmoid volvulus at a mean age of 80.5 years (range, 76-83). The volvulus was decompressed endoscopically before laparoscopic adhesiolysis and detorsion of the sigmoid. Finally, the sigmoid was approximated with the anterior abdominal wall, and 2 endoscopically placed percutaneous endoscopic colostomy tubes were inserted. Later, the external component of the percutaneous endoscopic colostomy tubes was removed, and the internal parts were passed by way of the rectum. RESULTS: Each operation was completed successfully in a mean time of 69 minutes and with no intraoperative complication. The mean postoperative stay was 20 days (range, 4-54). At median follow-up of 10.8 months, all patients were tube free with no incidence of recurrent volvulus, inadvertent tube traction, or leak. CONCLUSIONS: This preliminary report shows laparoscopic-assisted endoscopic sigmoidopexy to be a safe treatment modality for recurrent sigmoid volvulus. As such, it is particularly useful for elderly patients, for whom colectomy is a high-risk procedure.
- Published
- 2011
16. Preoperative Characteristics and Postoperative Behavior of Bowel Wall on Risk of Recurrence After Conservative Surgery in Crohn’s Disease
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Piergiorgio Danelli, Massimo Cristaldi, Gianluca M. Sampietro, Gabriele Bianchi Porro, Antonio Russo, Giovanni Maconi, and Angelo Maria Taschieri
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Adult ,Male ,Reoperation ,medicine.medical_specialty ,Malabsorption ,medicine.medical_treatment ,Review ,Inflammatory bowel disease ,Crohn Disease ,Recurrence ,Risk Factors ,Strictureplasty ,medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Proportional Hazards Models ,Ultrasonography ,Crohn's disease ,medicine.diagnostic_test ,business.industry ,Prognosis ,medicine.disease ,Short bowel syndrome ,Survival Analysis ,Surgery ,Endoscopy ,Intestines ,Bowel obstruction ,Female ,business - Abstract
Crohn’s disease (CD) is a chronic condition with an unpredictable course that is frequently characterized by a high rate of recurrence and in most patients a need for surgical treatment. Approximately 60% to 70% of patients require at least one surgical treatment, 1 often for bowel obstruction. In the past, wide resections have proved to be ineffective in preventing relapses, and repeated resective surgery can lead to malabsorption and short bowel syndrome in many instances. 2–5 During the past decade, strictureplasty and new bowel-sparing techniques have therefore been proposed for the conservative treatment of intestinal strictures. 4,6–9 The early postoperative results show that these techniques are effective and safe in terms of complications and death; further, long-term clinical and surgical recurrence rates are comparable with those observed after conventional resective surgery. 10–12 However, despite these encouraging results, the clinical course of CD and the behavior of the diseased intestinal walls after conservative surgery have so far been little investigated. Ultrasonography has recently been proposed as an accurate means of evaluating bowel walls in patients with CD. 13–18 Several studies have shown that transabdominal ultrasound can detect transmural changes and the degree of thickness of intestinal bowel wall, 19–21 and this technique is as accurate as barium radiology or scintigraphy in assessing the presence, location, and extent of inflammatory bowel disease, 15,18,21 particularly in bowel segments such as the ileum that are not easily to assess by endoscopy. It has also been shown that ultrasound can detect recurrences after “radical” surgical resections 22,23 and the intestinal complications of CD. 24,25 No study has yet evaluated the behavior of the thickness of diseased intestinal wall after conservative surgery in CD, or whether the presurgical ultrasound characteristics and postsurgical behavior of bowel wall thickness (BWT) have prognostic implications on clinical and surgical recurrences. The aims of this study were to evaluate in patients with CD using transabdominal ultrasound the morphologic characteristics of the diseased bowel wall before and after conservative surgery and to assess whether these characteristics and their postoperative behavior are useful prognostic factors for clinical and surgical recurrence after conservative surgery.
- Published
- 2001
17. Primary Liver Adenomatosis
- Author
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M.P.L. Rovati, Angelo Maria Taschieri, Maurizio Mezzabotta, Massimo Cristaldi, Alessandro Lesma, Marco Elli, Luca Vago, and Dario Conte
- Subjects
medicine.medical_specialty ,Abdominal pain ,Orthotopic liver transplantation ,medicine.diagnostic_test ,Adenoma ,Poor compliance ,business.industry ,medicine.medical_treatment ,Optimal treatment ,Gastroenterology ,Disease ,Liver transplantation ,medicine.disease ,Surgery ,Biopsy ,medicine ,medicine.symptom ,business - Abstract
Background/Aims: Liver adenomatosis is an uncommon condition and so far only 13 cases fulfilling the requirements for its diagnosis have been reported in the literature. Optimal treatment of the disease and follow-up criteria are still the subject of debate. Methods: We report on 2 cases of liver adenomatosis. In both cases definite diagnosis was obtained only intraoperatively on biopsy. Results: In neither case was liver transplantation done, due either to patient refusal or foreseeable poor compliance. Prolonged strict follow-up failed to demonstrate malignant changes. Conclusions: Removal of the huge masses often responsible for abdominal pain is the only real indication for resective surgery. Orthotopic liver transplantation should be reserved for those cases in which malignant changes are suspected due to elevation of the α-fetoprotein concentration or gross modifications in the shape of the hepatic lesions.
- Published
- 1998
18. Ischemic gall bladder perforation: a complication of type A aortic dissection
- Author
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Javed Khan, Neerod Kumar Jha, Massimo Cristaldi, Rajappan Arun Kumar, Moataz Ayman, Charles Ahene, and Norbert Augustin
- Subjects
Pulmonary and Respiratory Medicine ,Adult ,Male ,medicine.medical_specialty ,Ischemia ,Diagnostic tools ,Appropriate use ,Risk Assessment ,Marfan Syndrome ,Blood Vessel Prosthesis Implantation ,medicine ,Humans ,Digestive System Surgical Procedures ,Aortic dissection ,Aortic Aneurysm, Thoracic ,Rupture, Spontaneous ,business.industry ,Angiography ,Bladder Perforation ,Gallbladder ,medicine.disease ,Combined Modality Therapy ,Surgery ,Aortic Dissection ,Treatment Outcome ,Acute type ,Cardiology and Cardiovascular Medicine ,Complication ,business ,Tomography, X-Ray Computed ,Visceral ischemia ,Follow-Up Studies - Abstract
Malperfusion of end organs occurs in 20% to 40% patients with acute type A aortic dissection. Because irreversible ischemia is a time-dependent event, expedient diagnosis and treatment are necessary. We herein report successful surgical management of a patient with acute type A aortic dissection causing transient gut ischemia and a rare gall bladder perforation. We implemented one-stage surgical and laparoscopic management approach for the diagnosis and treatment. Increased awareness of this complication and appropriate use of available diagnostic tools may improve the outcome in similar patients. Patients with aortic dissection complicated by visceral ischemia require a prompt sequential and rational multidisciplinary approach for successful management.
- Published
- 2012
19. A procedure to estimate the seismic hazard in an urban area: an application to Acireale (Eastern Sicily)
- Author
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Domenico Bella, Massimo Cristaldi, F. Barone, Stefano Gresta, and Sebastiano Imposa
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Global and Planetary Change ,Peak ground acceleration ,Earthquake scenario simulations ,Seismic microzonation ,Local site amplification ,Soil Science ,Geology ,Environmental Seismic Intensity scale ,Seismic noise ,Pollution ,Earthquake scenario ,Seismic hazard ,Earthquake simulation ,Seismogenic faults ,Urban seismic risk ,H/V spectral ratios ,Environmental Chemistry ,Local site amplification, H/V spectral ratios ,Seismology ,Earth-Surface Processes ,Water Science and Technology - Abstract
A “standard procedure” to characterize the seismic hazard of a given area was proposed. It is based on a multidisciplinary approach implying: (1) the knowledge of the seismic history of the area; (2) detailed geological surveys; (3)seismic noise measurements; (4) simulations of earthquake scenarios. The downtown of Acireale, a typical baroque town located on Eastern Sicily, was chosen as the “test area”. A catalog of the local seismogenic faults (able to generate earthquakes in historical times) has been compiled, as well as a seismic catalog for the effects of both local and regional earthquakes. The analysis of both catalogs allowed us to make the following conclusions: (1) the most important seismogenic faults affecting the Acireale municipality do not affect the downtown, while the related local earthquakes attenuate their energy (and intensity) in short (few km) distances; (2) the highest seismic intensity (degree X) experienced in Acireale downtown was caused by the 1693 regional earthquake; (3) over the last 140 years, the downtown has experienced the highest intensity value of VII only once, while six times the intensity was VI. On the whole, this implies a moderate seismic hazard. The estimation of the seismic hazard has been also approached by the experimental method of recording seismic noise. Measurements have been performed at seven different sites, where drills gave detailed information on the shallow subsurface geology to obtain HV (horizontal/vertical) spectral ratios. On the whole, the highest site amplification factor was moderate (about 7). A further investigation based on synthetic seismograms (and spectra) produced by simulating two given earthquake scenarios was also performed. The two scenarios are, respectively, representative of the largest expected earthquake in the area (the 1693 shock) and of a moderate (magnitude ca. 5.5) local earthquake (as the 1818 one). Moderate to strong locally expected accelerations were evidenced.
- Published
- 2011
20. Femoro-popliteal by-pass occlusion following mesh-plug for prevascular femoral hernia repair
- Author
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Marco Elli, Piergiorgio Danelli, M. Pisacreta, Massimo Cristaldi, Gianluca Vago, Angelo Maria Taschieri, and Gianluca M. Sampietro
- Subjects
medicine.medical_specialty ,business.industry ,Femoral hernia repair ,Mesh plug ,Anastomosis ,Femoral hernia ,medicine.disease ,Surgery ,Apposition ,surgical procedures, operative ,Femoro-popliteal ,Occlusion ,medicine ,business ,Abdominal surgery - Abstract
Mesh plug repair for both inguinal and femoral hernias had a minimal number of postoperative complications reported. Among femoral hernias, the prevascular type represents a variant, because of the peculiar position of the sac strictly adjacent to the vessels. The authors report a case of femoral occlusion following femoro-popliteal by-pass and concomitant homolateral femoral hernia repair by cylindrical polypropylene plug not secured by sutures, which laid directly on the vessels. This complication occurs three months following surgery, the plug being displaced over and tightly adherent to the femoral-graft anastomosis. The apposition of a polypropylene mesh plug directly over the PTFE vascular graft could have stimulated the massive local fibrous reaction found at histology, a reaction not explained by the insertion of the PTFE only. The authors suggest that polypropylene plugs for repair of prevascular type of femoral hernias should be avoided, when concomitant or future arterial grafting procedures are needed.
- Published
- 1997
21. A prospective, longitudinal study of nonconventional strictureplasty in Crohn's disease
- Author
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Gianluca M, Sampietro, Massimo, Cristaldi, Giovanni, Maconi, Fabrizio, Parente, Alessandra, Sartani, Sandro, Ardizzone, Piergiorgio, Danelli, Gabriele, Bianchi Porro, and Angelo Maria, Taschieri
- Subjects
Adult ,Intestines ,Male ,Treatment Outcome ,Crohn Disease ,Recurrence ,Humans ,Female ,Prospective Studies ,Middle Aged ,Algorithms ,Digestive System Surgical Procedures - Abstract
Bowel-sparing techniques have been proposed to avoid extended or repeated resections in patients with Crohn'rsquo;s disease (CD), but without precise indications, prospective evaluation, and with a technically limited repertoire.A prospective longitudinal study of new nonconventional strictureplasties (NCSP) in order to evaluate the safety, type and site of recurrence, and longterm clinical and surgical efficacy.Between January 1993 and December 2002, 102 among 305 consecutive patients underwent at least one NCSP for complicated CD. Patients were treated following precise indications and then included in a prospective database with scheduled followup. Factors claimed to influence postoperative and longterm outcomes and type and site of recurrence were analyzed. We performed 48 ileoileal side-to-side isoperistaltic strictureplasty (SP), 41 widening ileocolic SP, 32 ileocolic side-to-side isoperistaltic SP, associated with Heineke-Mikulicz SP (in 80 procedures) or with minimal bowel resections or both (in 47 procedures). Postoperative mortality was nil; complication rate was 5.7%. Ten years clinical and surgical recurrence rates were 43% and 27%, respectively. Recurrence rate on an NCSP site was 0.8%. No specific factor was identified as related to postoperative or longterm outcomes.Perioperative and longterm results of NCSP are comparable to or even better than both conservative and resective surgery as reported in the literature, with a low recurrence rate on the NCSP site. Considering the unpredictability of the clinical course of CD and the lifetime need for surgical procedures, NCSP, together with minimal resection and classic SP repertoire, should be considered first-line treatment in complicated CD.
- Published
- 2003
22. Oxidative stress, vitamin A and vitamin E behaviour in patients submitted to conservative surgery for complicated Crohn's disease
- Author
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G. Bianchi Porro, Giovanni Maconi, Angelo Maria Taschieri, Piergiorgio Danelli, Massimo Cristaldi, Benvenuto Cestaro, M.P.L. Rovati, Giovanna Cervato, R. Cervellione, and Gianluca M. Sampietro
- Subjects
Vitamin ,Adult ,Male ,medicine.medical_specialty ,Time Factors ,Thiobarbituric acid ,medicine.medical_treatment ,medicine.disease_cause ,Thiobarbituric Acid Reactive Substances ,Antioxidants ,Lipid peroxidation ,chemistry.chemical_compound ,Crohn Disease ,Settore BIO/10 - Biochimica ,medicine ,Humans ,Vitamin E ,Vitamin A ,Crohn's disease ,Hepatology ,medicine.diagnostic_test ,biology ,business.industry ,C-reactive protein ,antioxidants ,vitamin A ,vitamin E ,lipid peroxidation ,surgery ,Gastroenterology ,medicine.disease ,Surgery ,Oxidative Stress ,chemistry ,Erythrocyte sedimentation rate ,Case-Control Studies ,biology.protein ,Female ,Lipid Peroxidation ,business ,Oxidative stress - Abstract
Aims. To assess whether plasma peroxidation and plasma levels of antioxidant compounds are correlated with clinical and biochemical activity in complicated Crohn's disease patients, and to evaluate whether the relief of obstructive complication by conservative surgery has any effect on the oxidative stress. Patients and Methods. From May 1998 to May 2000, 20 Crohn's disease patients were studied. Basal peroxidative state (basal thiobarbituric acid reactive substances), peroxidative state after stimulation with copper sulfate (stimulated thiobarbituric acid reactive substances), lag time of plasma peroxidation susceptibility, plasma levels of vitamin E and A, C reactive protein, erythrocyte sedimentation rate and Crohn's disease activity index, were determined, before surgery, then 2 months and 1 year after surgery. A group of 134 healthy volunteers were used as controls. All patients were treated by conservative surgical procedures (i.e., strictureplasty and/or minimal resections). Student t test for paired and unpaired data and Spearman R correlation coefficient were calculated. Result. Peroxidative plasma levels, as well as inflammatory indices, are significantly reduced 2 months and 1 year after surgery (p
- Published
- 2002
23. Bowel ultrasound in assessment of Crohn's disease and detection of related small bowel strictures: a prospective comparative study versus x ray and intraoperative findings
- Author
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Simona Bollani, Roberto Bianco, Gianluca M. Sampietro, Massimo Cristaldi, Andrea Anderloni, N. Franceschelli, Giovanni Maconi, Angelo Maria Taschieri, F. Parente, and G. Bianchi Porro
- Subjects
Adult ,Male ,medicine.medical_specialty ,Colorectal cancer ,medicine.medical_treatment ,Colonoscopy ,Contrast Media ,Enema ,Gastroenterology ,Sensitivity and Specificity ,chemistry.chemical_compound ,Crohn Disease ,Recurrence ,Internal medicine ,medicine ,Humans ,Aged ,Ultrasonography ,Crohn's disease ,Sicus ,medicine.diagnostic_test ,biology ,business.industry ,Ileal Diseases ,digestive, oral, and skin physiology ,Inflammation and Inflammatory Bowel Disease ,Double-contrast barium enema ,Middle Aged ,medicine.disease ,biology.organism_classification ,digestive system diseases ,Radiography ,Barium sulfate ,chemistry ,Female ,Barium Sulfate ,business ,Complication ,Intestinal Obstruction - Abstract
Background and aim: Despite the fact that bowel ultrasound (US) has recently been proved to be useful in the assessment of bowel diseases, uncertainty persists as to its diagnostic role in patients with complicated Crohn's disease (CD). Therefore, we have prospectively investigated the accuracy of US compared with x ray procedures and intraoperative findings in detecting small bowel strictures complicating CD as well as its reliability in assessing disease extent and location within the bowel. Methods: A series of 296 consecutive patients with proven CD admitted to L Sacco University Hospital between 1997 and 1999, having undergone complete radiographic evaluation (including small bowel x ray, colonoscopy, or double contrast barium enema), were enrolled in the study. Bowel US was performed in each patient by two experienced operators unaware of the results of other diagnostic procedures. The accuracy of US in detecting strictures compared with x ray studies was determined separately in two different groups of patients: 211 patients treated conservatively (non-operative CD) and 85 patients who were candidates for surgery for CD complications or unresponsiveness to medical therapy (operative CD). Results: Overall sensitivity and specificity of US in assessing the anatomical distribution of CD were 93% and 97%, respectively. The extent of ileal disease measured at US correlated well with that determined by x ray (r=0.52, p
- Published
- 2002
24. The vascularity of internal fistulae in Crohn's disease: an in vivo power Doppler ultrasonography assessment
- Author
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F. Parente, Giovanni Maconi, Simona Bollani, Giuseppe Sampietro, G. Bianchi Porro, Antonio Russo, Massimo Cristaldi, and F. Dottorini
- Subjects
Adult ,Male ,medicine.medical_specialty ,Duplex ultrasonography ,Radiography ,Fistula ,education ,Vascularity ,Crohn Disease ,Ileum ,Intestinal Fistula ,Medicine ,Humans ,Ultrasonography, Doppler, Color ,Aged ,Crohn's disease ,business.industry ,Ileal Diseases ,Gastroenterology ,Inflammation and Inflammatory Bowel Disease ,Blood flow ,Middle Aged ,medicine.disease ,medicine.anatomical_structure ,Regional Blood Flow ,Vascular resistance ,Female ,Vascular Resistance ,Radiology ,medicine.symptom ,business ,Complication - Abstract
Aim: To evaluate the efficacy of power Doppler sonography (US) in depicting internal fistulae and their vascularity, and to study the characteristics of blood flow within the fistula wall. Patients and methods: The study involved 45 consecutive patients with Crohn's disease and suspected internal fistulae detected by grey scale US. The fistulae were subsequently evaluated using power Doppler US to reveal any areas of increased vascularity, and the results were compared with radiographic, endoscopic, or intraoperative findings. Whenever feasible, we also performed spectral analysis of blood flow revealed by power Doppler US, calculated its resistance index (RI), and analysed its characteristics, reproducibility, and relationship with biochemical and clinical variables (Crohn's disease activity index, disease duration, location, and abdominal complications). Results: Power Doppler US revealed vascularity in all of the internal fistulae that where subsequently confirmed by diagnostic procedures. In the case of intra-abdominal abscesses in the vicinity of the fistula, vascular signals were detected mostly around and not within the lesions. The intensity and distribution of the signals differed within the fistulae tracks and had only slight day to day reproducibility; furthermore, there was no significant correlation with clinical or biochemical variables. Spectral analyses of blood flow within the fistulae revealed arterial flow in 96.7% of patients (median RI 0.715). RI was a more reproducible parameter and significantly correlated with clinical (r= 0.54) and biochemical activity (r= 0.56) of CD. It was also higher in fistulae complicated by abscesses. Conclusion: Power Doppler US can reveal the presence of vasculature within the wall of internal fistulae and therefore enhance grey scale US performance. The RI characteristics of blood flow within the fistulae are reproducible and correlate with biochemical and clinical disease activity.
- Published
- 2002
25. Long-term results and multivariate analysis of prognostic factors in 138 consecutive patients operated on for Crohn's disease using 'bowel-sparing' techniques
- Author
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Piergiorgio Danelli, Gianluca M. Sampietro, Angelo Maria Taschieri, Gabriele Bianchi Porro, Simona Bollani, and Massimo Cristaldi
- Subjects
Adult ,Male ,Reoperation ,medicine.medical_specialty ,Multivariate analysis ,Time Factors ,medicine.medical_treatment ,Disease ,Crohn Disease ,Ileum ,Recurrence ,Risk Factors ,Strictureplasty ,medicine ,Humans ,Minimally Invasive Surgical Procedures ,Prospective Studies ,Risk factor ,Colectomy ,Proportional Hazards Models ,Crohn's disease ,Proportional hazards model ,business.industry ,Mortality rate ,General Medicine ,Perioperative ,medicine.disease ,Prognosis ,Surgery ,Multivariate Analysis ,Female ,business - Abstract
Background: Conservative surgery has become accepted as a useful option for the surgical treatment of complicated Crohn’s disease (CD). Methodts: One hundred thirty-eight consecutive patients treated with strictureplasty or miniresections for complicated CD have been observed prospectively. The possible influence of a number of variables on the risk of recurrence was investigated using the Cox proportional hazard model, and a time-to-event analysis was made using the Kaplan-Meier function. Results: There was no perioperative mortality; the morbidity rate was 5.7%. A close correlation was found between the risk of recurrence and the time between diagnosis and first surgery. The overall 5-year recurrence rate was 24%, being 36% in the patients requiring surgery within 1 year of diagnosis and 14% in those operated on more than 1 year after diagnosis. Conclusions: Risk factor analysis highlighted a group of patients at high risk of surgical recurrence. Given that our results are similar to those reported in other series, we consider strictureplasty and miniresections safe and effective procedures for the treatment of complicated CD.
- Published
- 2000
26. Early perioperative results and surgical recurrence after strictureplasty and miniresection for complicated Crohn's disease
- Author
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G. Montecamozzo, Piergiorgio Danelli, Massimo Cristaldi, Angelo Maria Taschieri, Tiziano Porretta, and Gianluca M. Sampietro
- Subjects
Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Disease ,Hemoglobins ,Crohn Disease ,medicine ,Strictureplasty ,Humans ,Digestive System Surgical Procedures ,Crohn's disease ,business.industry ,Gastroenterology ,Perioperative ,Bowel resection ,Middle Aged ,Short bowel syndrome ,medicine.disease ,Surgery ,Exact test ,Parenteral nutrition ,Logistic Models ,Treatment Outcome ,Hematocrit ,Female ,business - Abstract
Background/Aims: Strictureplasty (SP) or miniresective ‘bowel-sparing’ techniques (MR) can prevent the risk of intestinal stomia and short bowel syndrome in patients affected by Crohn’s disease (CD). The aim of this study was to analyze the perioperative morbidity and mortality in 104 of 138 consecutive patients treated for CD complications using bowel-sparing techniques. We also considered the factors that may be related to the risk of perioperative complications and the long-term outcome. Methods: One hundred and four patients were treated with SP and/or MR and then included in a prospectively maintained database. The factors claimed to influence perioperative complications were analyzed using Fisher’s exact test for categorical observations and the Mann-Whitney U test for continuous variables. A multivariate analysis, using logistic regression, and a long-term time-to-event analysis using the Kaplan-Meier function, were also performed. Results: Perioperative mortality was nil. In relation to the 6 postoperative complications (5.8%), 4 patients underwent minimal bowel resection (MR), 1 a MR with SP, and 1 SP alone. Three of these patients (2.9%) needed reoperation for septic complications, and 3 (2.9%) were treated as outpatients for enterocutaneous fistulas. A correlation (p < 0.05) was found between low serum hemoglobin levels and postoperative complications at univariate and multivariate analyses. The 5-year surgical recurrence-free rate was 75% overall, 73% for patients treated with SP, 78% with MR, and 77% with MR + SP. Conclusions: Postoperative complications are not related to conservative or miniresective surgery even when active disease is present at the resection margins or the site of SP. The higher risk reported for patients with low serum hemoglobin and hematocrit levels suggests that surgeons should consider using preoperative iron and vitamin support, parenteral nutrition and erythropoietin therapy, when necessary, in those cases. Our postoperative morbidity, mortality and long-term surgical recurrence rate results support the efficacy and safety of SP and MR surgery in the treatment of complicated CD.
- Published
- 2000
27. Description of new 'bowel-sparing' techniques for long strictures of Crohn's disease
- Author
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Angelo Maria Taschieri, Barbara Molteni, Massimo Cristaldi, Gabriele Bianchi Porro, Piergiorgio Danelli, Marco Elli, and M.P.L. Rovati
- Subjects
Adult ,Male ,medicine.medical_specialty ,Colon ,medicine.medical_treatment ,Severe disease ,Lumen (anatomy) ,Long segment ,Ileocecal valve ,Crohn Disease ,Ileum ,Strictureplasty ,Methods ,Medicine ,Humans ,Crohn's disease ,Surgical approach ,Ileocecal Valve ,business.industry ,Anastomosis, Surgical ,General Medicine ,medicine.disease ,Surgery ,Stenosis ,medicine.anatomical_structure ,Female ,business ,Intestinal Obstruction - Abstract
In the period of January 1993 to December 1995 we operated on 55 patients with various complications of Crohn's disease. In properly selected cases, obstructive complications of Crohn's disease can be treated effectively by strictureplasty. Long strictures, even if a narrow lumen is still present, are commonly managed by resection, as classic strictureplasties cannot be done; also Finney strictureplasty seems inadequate, as it creates a blind loop that favors bacterial overgrowth and fecal stasis. Three original "sparing bowel" surgical approaches are proposed as possible alternative in the treatment of long stricture in Crohn's disease. We perform side-to-side ileoileal plasty whenever we are faced with severe narrowing of a long segment of small bowel (>10 cm); side-to-side ileocolic plasty whenever very severe disease with narrowing of ileocaecal valve is present; and ileocaecal plasty when terminal ileitis involves the very distal end of the small bowel, but sparing or only minimally affecting the ileocaecal valve. The above-mentioned procedures are described in detail and the clinical outcomes related to the first 8-patient series of our institution are presented.
- Published
- 1997
28. 81 PS Non conventional strictureplasty for intestinal complications in Crohn's disease: Long-term results of 90 procedures in 77 patients
- Author
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Giuseppe Sampietro, Giovanni Maconi, Angelo Maria Taschieri, Massimo Cristaldi, Piergiorgio Danelli, and A. Sartani
- Subjects
medicine.medical_specialty ,Crohn's disease ,Hepatology ,business.industry ,medicine.medical_treatment ,Gastroenterology ,Long term results ,medicine.disease ,Surgery ,Internal medicine ,medicine ,Strictureplasty ,business - Published
- 2002
29. 18 P Safety, efficacy and long term prognosis of extended D2 and D3 lymphadenectomy for gastric cancer
- Author
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Angelo Maria Taschieri, V. Panizzo, H. Kurihara, Massimo Cristaldi, Piergiorgio Danelli, Giuseppe Sampietro, and Paolo Fociani
- Subjects
Oncology ,medicine.medical_specialty ,Hepatology ,business.industry ,Internal medicine ,Gastroenterology ,medicine ,Cancer ,D3 lymphadenectomy ,medicine.disease ,business ,Term (time) - Published
- 2002
30. Bowel ultrasound (US) in assessment of Crohn's disease (CD) and detection of related small bowel strictures a prospective comparative study versus X-rays and intraoperative findings
- Author
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Massimo Cristaldi, Simona Bollani, Gianluca M. Sampietro, Giovanni Maconi, Angelo Maria Taschieri, N. Franceschelli, Roberto Bianco, Andrea Anderloni, F. Parente, and G. Bianchi Porro
- Subjects
medicine.medical_specialty ,Crohn's disease ,Hepatology ,business.industry ,Internal medicine ,Ultrasound ,Gastroenterology ,medicine ,Radiology ,business ,medicine.disease - Published
- 2001
31. Contrast radiology, computed tomography (CT) and ultrasonography (US) in detecting abdominal complications of Crohn's disease (CD).A prospective comparative study
- Author
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Sandro Ardizzone, Giovanni Maconi, Angelo Maria Taschieri, Massimo Cristaldi, Giovanni Pompili, Gianluca M. Sampietro, Antonio Russo, F. Parente, and G. Bianchi Porro
- Subjects
Contrast radiology ,Crohn's disease ,medicine.medical_specialty ,Hepatology ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Medicine ,Computed tomography ,Radiology ,Ultrasonography ,business ,medicine.disease - Published
- 2001
32. Surgical strategy, complications and long term prognosis of conservative surgery in Crohn's disease
- Author
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Giovanni Maconi, Angelo Maria Taschieri, Piergiorgio Danelli, Massimo Cristaldi, and Giuseppe Sampietro
- Subjects
Crohn's disease ,medicine.medical_specialty ,Surgical strategy ,Hepatology ,business.industry ,Gastroenterology ,medicine ,medicine.disease ,business ,Surgery ,Term (time) - Published
- 2000
33. Normalization of bowel wall after strictureplasty and miniresection for complicated Crohn's disease
- Author
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Simona Bollani, Giovanni Maconi, Angelo Maria Taschieri, Piergiorgio Danelli, Giuseppe Sampietro, and Massimo Cristaldi
- Subjects
Normalization (statistics) ,medicine.medical_specialty ,Crohn's disease ,Hepatology ,business.industry ,medicine.medical_treatment ,Gastroenterology ,Strictureplasty ,Medicine ,Radiology ,business ,medicine.disease ,Bowel wall - Published
- 2000
34. Different strictureplasty options to avoid resections in complicated Crohn's disease
- Author
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Giuseppe Sampietro, Piergiorgio Danelli, Giovanni Maconi, Massimo Cristaldi, and Angelo Maria Taschieri
- Subjects
medicine.medical_specialty ,Crohn's disease ,Hepatology ,business.industry ,General surgery ,medicine.medical_treatment ,Gastroenterology ,medicine ,Strictureplasty ,business ,medicine.disease - Published
- 2000
35. Diagnosis of fistulas in Crohn's disease with power doppler sonography (PDUS)
- Author
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Giuseppe Sampietro, Giovanni Maconi, Simona Bollani, Sandro Ardizzone, G. Bianchi Porro, and Massimo Cristaldi
- Subjects
Crohn's disease ,Power doppler ,medicine.medical_specialty ,Hepatology ,business.industry ,Gastroenterology ,Medicine ,Radiology ,business ,medicine.disease - Published
- 2000
36. Conventional and non-conventional strictureplasty for surgical treatment of Crohn's disease
- Author
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Gianluca M. Sampietro, Angeld Maria Taschieri, Massimo Cristaldi, and Piergiorgio Daneiii
- Subjects
medicine.medical_specialty ,Crohn's disease ,Hepatology ,business.industry ,medicine.medical_treatment ,Gastroenterology ,Strictureplasty ,Medicine ,business ,Surgical treatment ,medicine.disease ,Surgery - Published
- 2000
37. Surgical recurrence after conservative surgery in Crohn's disease
- Author
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Angelo Maria Taschieri, Massimo Cristaldi, Piergiorgio Danelli, and Gianluca M. Sampietro
- Subjects
medicine.medical_specialty ,Crohn's disease ,Hepatology ,business.industry ,Gastroenterology ,medicine ,medicine.disease ,business ,Surgery - Published
- 2000
38. Contrast radiology, computed tomography and ultrasonography in detecting internal fistulas and intra-abdominal abscesses in Crohn's disease: A prospective comparative study
- Author
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Antonio Russo, Giovanni Maconi, Sandro Ardizzone, Angelo Maria Taschieri, Gabriele Bianchi Porro, Gianluca M. Sampietro, F. Parente, Massimo Cristaldi, Giovanni Pompili, Giovanni Matacena, and Giancarlo Arborio
- Subjects
medicine.medical_specialty ,Abdominal Abscess ,Radiography ,Fistula ,education ,Contrast Media ,Colonoscopy ,Enema ,Crohn Disease ,Intestinal Fistula ,medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Abscess ,Ultrasonography ,Crohn's disease ,Hepatology ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,medicine.disease ,medicine.anatomical_structure ,Barium ,Abdomen ,Tomography ,Radiology ,Tomography, X-Ray Computed ,business - Abstract
Accurate assessment of intestinal complications of Crohn's disease (CD) is extremely important, both in clinical practice and in trials. The accuracy of radiographic and ultrasonographic diagnosis of internal fistulae and abscesses complicating CD is still debated and requires further investigation. We compared ultrasonography (US) and contrast radiography in detecting intestinal fistulae and abscesses complicating CD.A prospective study was carried out on 625 consecutive CD patients who underwent complete evaluation of the intestinal tract by means of colonoscopy and double contrast barium enema, small bowel enteroclysis, and abdominal ultrasound (US). Computed tomography (CT) was also carried out in cases of severe CD with clinical suspicion of septic complications. The accuracy of US, barium radiology, and CT in detecting internal fistulae and abscesses was assessed by comparing results with intraoperative findings in 128 consecutive patients who underwent operation immediately after diagnostic workup.Internal fistulae and intra-abdominal abscesses were identified intraoperatively in 56 (43.7%) and 26 (20.3%) patients, respectively. Diagnostic accuracy of US and x-ray studies in detecting internal fistulae was comparable (85.2% vs 84.8%), with sensitivity of 71.4% for US and 69.6% for x-ray studies, and specificity of 95.8% for both. Combination of radiographic techniques and US significantly improved diagnostic accuracy in detection of internal fistulae. In severe cases of CD with clinical suspicion of septic complications such as abdominal mass or fever, the accuracy of US, barium studies, and CT was 88.5%, 80.3%, and 77%, respectively (p = ns). The presence of abscesses was correctly detected in 90.9% of cases by means of US and in 86.4% by CT (p = ns), although accuracy was higher for CT (91.8%) than for US (86.9%) because of false positive results in US studies.Despite the fact that barium radiology is widely considered the method of choice in detection of internal fistulae, accuracy is not entirely satisfactory. Comparable accuracy was found for US and CT. The combination of barium and US studies, or the sole use of US in more CD patients with more severe disease, can reliably detect most internal fistulae and abscesses.
39. Salvo
- Author
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Acaba Produzioni, production company., Cristaldi Pictures, production company., Grassadonia, Fabio, director., Piazza, Antonio, director., Cristaldi, Massimo, 1956- producer., Mosca, Fabrizio (Producer), producer., Piazza, Antonio, director, Grassadonia, Fabio, director, Mosca, Fabrizio, producer, and (1956), Massimo Cristaldi, producer
- Published
- 2013
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