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1. High-dose colistin pharmacokinetics in critically ill patients receiving continuous renal replacement therapy

2. Management of intra-abdominal infections: recommendations by the Italian council for the optimization of antimicrobial use

3. Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortalityResearch in context

4. Impact of Hemoglobin Levels on Composite Cardiac Arrest or Stroke Outcome in Patients With Respiratory Failure Due to COVID-19

5. Adjunctive immunotherapeutic agents in patients with sepsis and septic shock: a multidisciplinary consensus of 23

6. Follow-up short and long-term mortalities of tracheostomized critically ill patients in an Italian multi-center observational study

7. Update on vitamin D role in severe infections and sepsis

8. Epidemiology and risk factors for mortality in critically ill patients with pancreatic infection

9. High versus standard blood pressure target in hypertensive high-risk patients undergoing elective major abdominal surgery: a study protocol for the HISTAP randomized clinical trial

10. Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms

11. Lung microbiota composition, respiratory mechanics, and outcomes in COVID-19-related ARDS

12. Clinical features and 28-day mortality predictors of vaccinated patients admitted to a COVID-19 ICU hub in Italy

13. The role of beta-blocker drugs in critically ill patients: a SIAARTI expert consensus statement

14. Physiological effects of awake prone position in acute hypoxemic respiratory failure

15. Successful Versus Failed Transition From Controlled Ventilation to Pressure Support Ventilation in COVID-19 Patients: A Retrospective Cohort Study

16. Comparative evaluation of three total full-face masks for delivering Non-Invasive Positive Pressure Ventilation (NPPV): a bench study

17. Long-term outcome of COVID-19 patients treated with helmet noninvasive ventilation vs. high-flow nasal oxygen: a randomized trial

18. Rationale and clinical application of antimicrobial stewardship principles in the intensive care unit: a multidisciplinary statement

19. Can carotid artery Doppler variations induced by the end-expiratory occlusion maneuver predict fluid responsiveness in septic shock patients?

20. Antimicrobial De-Escalation in Critically Ill Patients

21. Ultrasound-assessed lung aeration correlates with respiratory system compliance in adults and neonates with acute hypoxemic restrictive respiratory failure: an observational prospective study

22. Use of an innovative cuff pressure control and subglottic secretions drainage system in COVID-19 ARDS patients undergoing pronation

23. Helmet noninvasive support for acute hypoxemic respiratory failure: rationale, mechanism of action and bedside application

24. Risk factors for infections caused by carbapenem-resistant Enterobacterales: an international matched case-control-control study (EURECA)Research in context

25. Individualized positive end-expiratory pressure guided by end-expiratory lung volume in early acute respiratory distress syndrome: study protocol for the multicenter, randomized IPERPEEP trial

26. Gas conditioning during helmet noninvasive ventilation: effect on comfort, gas exchange, inspiratory effort, transpulmonary pressure and patient–ventilator interaction

28. Prediction of extubation outcome in critically ill patients: a systematic review and meta-analysis

29. A machine-learning parsimonious multivariable predictive model of mortality risk in patients with Covid-19

30. Machine learning using the extreme gradient boosting (XGBoost) algorithm predicts 5-day delta of SOFA score at ICU admission in COVID-19 patients

31. Flow Index: a novel, non-invasive, continuous, quantitative method to evaluate patient inspiratory effort during pressure support ventilation

32. Staphylococcus aureus ventilator-associated pneumonia in patients with COVID-19: clinical features and potential inference with lung dysbiosis

33. Diaphragm thickening fraction predicts noninvasive ventilation outcome: a preliminary physiological study

34. Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients

35. Expert consensus statements for the management of COVID-19-related acute respiratory failure using a Delphi method

36. Monitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ failure and survival in sepsis: a prospective observational multinational study

37. Are single-lumen 5Fr and triple-lumen 6Fr PICCs suitable for hemodynamic assessment by trans-pulmonary thermodilution? A pilot study

38. Use of critical care resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy

39. Acute respiratory failure in immunocompromised patients: outcome and clinical features according to neutropenia status

40. (1,3)-β-d-Glucan-based empirical antifungal interruption in suspected invasive candidiasis: a randomized trial

41. The importance of airway and lung microbiome in the critically ill

42. Respiratory physiology of COVID-19-induced respiratory failure compared to ARDS of other etiologies

43. Pharmacokinetics of high-dose tigecycline in critically ill patients with severe infections

45. Remdesivir plus Dexamethasone in COVID-19: A cohort study of severe patients requiring high flow oxygen therapy or non-invasive ventilation.

46. Antimicrobial Exposure in Critically Ill Patients with Sepsis-Associated Multi-Organ Dysfunction Requiring Extracorporeal Organ Support: A Narrative Review

47. Use of High-Dose Nebulized Colistimethate in Patients with Colistin-Only Susceptible Acinetobacter baumannii VAP: Clinical, Pharmacokinetic and Microbiome Features

48. Diagnosis and Treatment of Bacterial Pneumonia in Critically Ill Patients with COVID-19 Using a Multiplex PCR Assay: A Large Italian Hospital’s Five-Month Experience

50. Assessment of 28-Day In-Hospital Mortality in Mechanically Ventilated Patients With Coronavirus Disease 2019: An International Cohort Study

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