8 results on '"Mascia, Luigi"'
Search Results
2. The Increasing Role of CT-Guided Cryoablation for the Treatment of Liver Cancer: A Single-Center Report
- Author
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Pusceddu, Claudio, primary, Mascia, Luigi, additional, Ninniri, Chiara, additional, Ballicu, Nicola, additional, Zedda, Stefano, additional, Melis, Luca, additional, Deiana, Giulia, additional, Porcu, Alberto, additional, and Fancellu, Alessandro, additional
- Published
- 2022
- Full Text
- View/download PDF
3. Acute appendicitis in children: not only surgical treatment
- Author
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Caruso, Anna Maria, primary, Pane, Alessandro, additional, Garau, Roberto, additional, Atzori, Pietro, additional, Podda, Marcello, additional, Casuccio, Alessandra, additional, and Mascia, Luigi, additional
- Published
- 2017
- Full Text
- View/download PDF
4. Manuale di anestesia, rianimazione e terapia intensiva
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Marco Ranieri, Luciana Mascia, Luigi Tritapepe
5. Qualche riflessione sulla fascinazione esotista nelle scenografie di Antonio Basoli
- Author
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Valeria Rubbi, Inés Monteira Arias, Sabine Du Crest, Lucia Corrain, Chiara Giulia Morandi, Angela Ghirardi, Cristina Cassina, Barbara Baert, Agnès Blandeau, Fabrizio Lollini, Teodoro De Giorgio, Guillermo M. Jodra, Ignacio José García Zapata, Eleonora Cappuccilli, Gilberta Golinelli, Beniamino Della Gala, Camilla Murgia, Luigi Franchi, Dmitry Novokhatskiy, Federica Francesconi, Maria Portmann, Giulia Iseppi, Tímea Jablonczay, Paulo Catarino Lopes, Kira von Ostenfeld-Suske, Vittorio Fortunati, Larissa Carvalho, Donatella Biagi Maino, Erica Ciccarella, Alberto Carrera, Giovanni Cerro, Valeria Rubbi, Maurizio Ascari, Gino Scatasta, Rosa Lombardi, Esteban García Brosseau, Peter Mason, Maria Vittoria Spissu, Carolina Valenzuela Matus, Sandra Costa, Alessandra Mascia, Luigi Contadini, Ana Teresa Graça de Sousa, Antonino Rotolo, Katharina Jörder, Giulia Golla Tunno, Giacomo Tarascio, Marinella Pigozzi, Roberto Pinto, Elena Giovannini, Marco Albertoni, Michela Morgante., I. Graziani, M. V. Spissu, and Valeria Rubbi
- Subjects
Alterità, fascinazione, esotismo, scenografia - Abstract
Tra la fine del Settecento e gli inizi dell’Ottocento, il mondo orientale, africano o più esotico, diviene un terreno di invenzione in cui gli scenografi, come tanti artisti del tempo, mischiano le conoscenze archeologiche con l’ecclettismo dell’immaginazione. E forse, sono proprio le vicende ambientate fuori dall’Europa quelle in cui meglio è possibile scorgere le caratteristiche della sensibilità di Antonio Basoli (1774-1843) e l’attenzione che egli riserva agli stimoli culturali della sua epoca e al nascente esotismo, inteso come attrazione esercitata da un passato lontano che può, per similitudine o opposizione, divenire modello per l’occidente. Basoli sente forte il fascino dei mondi lontani leggendo le fonti, che saranno indagate attraverso documenti inediti, che circolavano in Europa; ma questa fascinazione svela una profonda ambivalenza: è l’occhio di un artista dell’Occidente che interpreta la cultura artistica orientale con strumenti linguistici ancora legati ai canoni di una scienza prospettica, forse incapace di cogliere una percezione visiva del tempo e dello spazio profondamente diversa. Infatti, nelle tavole che conservano la memoria dei suoi allestimenti (Il tempio d’Osiri in Egitto, Piazza cinese, Pagoda indiana, Un serraglio di Sidi-Ali in Algeri, Tempio del Sole a Cuzco, ecc.) si può apprezzare la scrupolosa cura nel documentarsi circa usi, costumi e monumenti dei popoli e paesi dove si svolgono le storie che metterà in scena; nello stesso tempo si può notare, tuttavia, come non si trasformi mai in puro esercizio filologico, in quanto l’immaginazione permette a Basoli di scegliere tra le fonti iconografiche a sua disposizione, in modo tale da isolare alcuni caratteri particolarmente significativi che vengono assunti come cifra di un determinato ambiente. Nell’individuare gli elementi architettonici che permettono allo spettatore di riconoscere il luogo fisico in cui è ambientata la vicenda, lo scenografo, tuttavia, isolandoli attraverso un cannocchiale prospettico, ne ignora lo spazio antropologico rischiando di violarne l’identità. Between the end of the 17th century and the beginning of the 18th century, the Oriental world, both the African and the exotic one as well, becomes a land of inventions where set designers, as many artists of that time, mix their archeological knowledge with the ecleptism of imagination. And perhaps, it is easier to catch the features of Antonio Basoli's sensitivity in the events set out of Europe as well as the attention that he points out in the cultural incentives of his period and in the growing exoticism, meant to be an attraction carried out by a far away past which can, either for simile or opposition, become a pattern for the Western world. Basoli deeply feels the fascination of far away worlds by reading the sources, which will be searched out trough unpublished documents that where already circulating in Europe; however, this fascination reveals a strong ambivalence: it's the mind of a Western artist who interprets the Oriental artistic culture trough linguistic devices still bound to the rules of a prospective science, which is maybe unable to get a visual perception of time and space extremely different. As a matter of fact, in the panels that keep that memory of his exhibitions (The Temple od Osiris in Egypt, The Chinese Square, The Indian Pagoda, The Sidi-Ali menagerie in Algeri, The Temple of the Sun in Cuzco, etc.), you can appreciate the detailed attention he paid to research traditions, customs and monuments of the people and the countries where the stories he displays are set. In the meantime you can notice, however, how that never turns into philological practice, as imagination allows Basoli to choose among the iconographic sources he has at his disposal, in order to isolate some particularly meaningful features which will be understood as a deal of a specific environment. By identifying architectural elements which allow the visitor to recognize the physical place where the story is set, the set designer, although he isolates them through prospective binoculars, he ignores their anthropological space, risking therefore violating their identity.
- Published
- 2019
6. Acute appendicitis in children: not only surgical treatment
- Author
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Alessandra Casuccio, Pietro Atzori, A. Pane, Marcello Podda, Roberto Garau, Luigi Mascia, Anna Maria Caruso, Caruso, Anna Maria, Pane, Alessandro, Garau, Roberto, Atzori, Pietro, Podda, Marcello, Casuccio, Alessandra, and Mascia, Luigi
- Subjects
Male ,medicine.medical_specialty ,Adolescent ,Abdominal ultrasound ,Unnecessary Surgery ,Surgery complication ,Unnecessary Procedures ,Conservative Treatment ,03 medical and health sciences ,0302 clinical medicine ,030225 pediatrics ,Anti-Bacterial Agent ,medicine ,Humans ,Appendectomy ,Uncomplicated appendicitis ,Appendiciti ,Prospective Studies ,Surgical treatment ,Child ,Ultrasonography ,business.industry ,General surgery ,General Medicine ,Evidence-based medicine ,Appendicitis ,Appendicular ma ,Surgery ,Anti-Bacterial Agents ,Conservative treatment ,Prospective Studie ,Early appendectomy ,Treatment Outcome ,030220 oncology & carcinogenesis ,Treatment study ,Child, Preschool ,Acute appendicitis ,Acute Disease ,Pediatrics, Perinatology and Child Health ,Female ,Acute appendiciti ,business ,Human ,Unnecessary Procedure - Abstract
Purpose An accurate diagnosis of acute appendicitis is important to avoid severe outcome or unnecessary surgery but management is controversial. The aim of study was to evaluate, in younger and older children, the efficacy of conservative management for uncomplicated appendicitis and the outcome of complicated forms underwent early surgery. Methods Children with acute appendicitis were investigated by clinical, laboratory variables and abdominal ultrasound and divided in two groups: complicated and uncomplicated. Complicated appendicitis underwent early surgery; uncomplicated appendicitis started conservative treatment with antibiotic. If in the next 24–48 h it was worsening, the conservative approach failed and patients underwent late surgery. Results A total of 362 pediatric patients were included. One hundred sixty-five underwent early appendectomy; 197 patients were at first treated conservatively: of these, 82 were operated within 24–48 h for failure. The total percentage of operated patients was 68.2%. An elevated association was found between surgery and ultrasound. Conclusions Conservative treatment for uncomplicated appendicitis had high percentage of success (58%). Complications in operated patients were infrequent. Our protocol was effective in order to decide which patients treat early surgically and which conservatively; specific red flags (age and onset) can identified patients at most risk of complications or conservative failure. Type of study: treatment study. Level of evidence II.
- Published
- 2017
7. Lenvatinib versus Sorafenib Second-Line Therapy in Patients with Hepatocellular Carcinoma Progressed to Atezolizumab plus Bevacizumab: A Retrospective Real-World Study.
- Author
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Persano M, Casadei-Gardini A, Tada T, Suda G, Shimose S, Kudo M, Rossari F, Yoo C, Cheon J, Finkelmeier F, Lim HY, Presa J, Masi G, Bergamo F, Amadeo E, Vitiello F, Kumada T, Sakamoto N, Iwamoto H, Aoki T, Chon HJ, Himmelsbach V, Iavarone MA, Cabibbo G, Montes M, Foschi FG, Vivaldi C, Soldà C, Sho T, Niizeki T, Nishida N, Steup C, Bruccoleri M, Hirooka M, Kariyama K, Tani J, Atsukawa M, Takaguchi K, Itobayashi E, Tsuji K, Ishikawa T, Tajiri K, Ochi H, Yasuda S, Toyoda H, Ogawa C, Nishimura T, Hatanaka T, Kakizaki S, Shimada N, Kawata K, Hiraoka A, Tada F, Ohama H, Nouso K, Morishita A, Tsutsui A, Nagano T, Itokawa N, Okubo T, Imai M, Kosaka H, Naganuma A, Koizumi Y, Nakamura S, Kaibori M, Iijima H, Hiasa Y, Mascia L, Foti S, Camera S, Piscaglia F, Scartozzi M, Cascinu S, and Rimini M
- Abstract
Introduction: The most frequently used first-line treatment in patients with advanced hepatocellular carcinoma (HCC) is atezolizumab plus bevacizumab. Upon progression after this treatment, the standard of care in many countries is sorafenib, due to the lack of reimbursement for other drugs. Several randomized trials are currently underway to clarify the best second-line therapy in patients with HCC. This real-world study aimed to compare outcomes reached by lenvatinib and sorafenib second-line therapy in this setting., Methods: The overall cohort included 891 patients with HCC from 5 countries treated with atezolizumab plus bevacizumab in first-line setting between October 2018 and April 2022. At the data cut-off (May 2022), 41.5% of patients were continuing a first-line treatment, 5.5% were lost at follow-up, and 53.0% of patients had progressive disease after first-line therapy. 51.5% of patients with progressive disease received a second-line treatment, while 48.5% did not receive any subsequent therapy. Between patients receiving second-line treatment, 11.1% of patients underwent transarterial chemoembolization, 21.0% received sorafenib, 35.4% underwent lenvatinib, and 32.5% were treated with other drugs., Results: Lenvatinib second-line subgroup achieved a median overall survival (mOS) of 18.9 months, significative longer (p = 0.01; hazard ratio [HR]: 2.24) compared to sorafenib subgroup that reached a mOS of 14.3 months. The multivariate analysis highlighted albumin-bilirubin 1 grade (p < 0.01; HR: 5.23) and lenvatinib second-line therapy (p = 0.01; HR: 2.18) as positive prognostic factors for OS. The forest plot highlighted a positive trend in terms of OS in favor of patients treated with lenvatinib second-line regardless of baseline characteristics before first-line therapy., Conclusion: These results suggest that, in patients with HCC progressed to first-line atezolizumab plus bevacizumab, lenvatinib second-line therapy is associated to an improved survival compared to sorafenib., (© 2024 S. Karger AG, Basel.)
- Published
- 2024
- Full Text
- View/download PDF
8. [Long term survival in patient with metastatic breast cancer treated with sacituzmab govitecan.]
- Author
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Mulas C and Mascia L
- Subjects
- Humans, Female, Camptothecin analogs & derivatives, Camptothecin administration & dosage, Camptothecin therapeutic use, Progression-Free Survival, Middle Aged, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Time Factors, Immunoconjugates, Breast Neoplasms drug therapy, Breast Neoplasms pathology, Antibodies, Monoclonal, Humanized administration & dosage, Antibodies, Monoclonal, Humanized therapeutic use
- Abstract
The clinical case presented refers to a woman suffering from metastatic breast cancer treated with sacituzumab govitecan (SG) who has a long progression-free survival. The case is characterized by the extreme aggressiveness of the neoplastic disease that relapses during adjuvant hormonal treatment with a metastatic disease that presents immunohistochemical characteristics different from the primary tumor. After first-line therapy with nabpaclitaxel and atezolizumab and the subsequent one with carboplatin and gemcitabine, both characterized by short PFS, the third line with SG is characterized by obtaining a complete response and a prolonged PFS as well as extreme tolerability that continues to this day after 15 months of treatment.
- Published
- 2024
- Full Text
- View/download PDF
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