1. Usefulness of intestinal fatty acid-binding protein in predicting strangulated small bowel obstruction.
- Author
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Hirotada Kittaka, Hiroshi Akimoto, Hitoshi Takeshita, Hiroyuki Funaoka, Hiroshi Hazui, Masao Okamoto, Hitoshi Kobata, and Yasuo Ohishi
- Subjects
Medicine ,Science - Abstract
BACKGROUND: The level of intestinal fatty acid-binding protein (I-FABP) is considered to be useful diagnostic markers of small bowel ischemia. The purpose of this retrospective study was to investigate whether the serum I-FABP level is a predictive marker of strangulation in patients with small bowel obstruction (SBO). METHODS: A total of 37 patients diagnosed with SBO were included in this study. The serum I-FABP levels were retrospectively compared between the patients with strangulation and those with simple obstruction, and cut-off values for the diagnosis of strangulation were calculated using a receiver operating characteristic curve. In addition, the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated. RESULTS: Twenty-one patients were diagnosed with strangulated SBO. The serum I-FABP levels were significantly higher in the patients with strangulation compared with those observed in the patients with simple obstruction (18.5 vs. 1.6 ng/ml p
- Published
- 2014
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