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8 results on '"Masala, Giovana"'

1. Healthy lifestyle and the risk of pancreatic cancer in the EPIC study

Author

Naudin, Sabine, Viallon, Vivian, Hashim, Dana, Freisling, Heinz, Jenab, Mazda, Weiderpass, Elisabete, Perrier, Flavie, McKenzie, Fiona, Bueno-de-Mesquita, H Bas, Olsen, Anja, Tjønneland, Anne, Dahm, Christina C., Overvad, Kim, Mancini, Francesca R., Rebours, Vinciane, Boutron-Ruault, Marie-Christine, Katzke, Verena, Kaaks, Rudolf, Bergmann, Manuela, Boeing, Heiner, Peppa, Eleni, Karakatsani, Anna, Trichopoulou, Antonia, Pala, Valeria, Masala, Giovana, Panico, Salvatore, Tumino, Rosario, Sacerdote, Carlotta, May, Anne M., van Gils, Carla H., Rylander, Charlotta, Borch, Kristin Benjaminsen, López, María Dolores Chirlaque, Sánchez, Maria-Jose, Ardanaz, Eva, Quirós, José Ramón, Exezarreta, Pilar Amiano, Sund, Malin, Drake, Isabel, Regnér, Sara, Travis, Ruth C., Wareham, Nick, Aune, Dagfinn, Riboli, Elio, Gunter, Marc J., Duell, Eric J., Brennan, Paul, and Ferrari, Pietro

Published
2020

2. Plasma concentration of 36 (poly)phenols and prospective body weight change in participants from the EPIC cohort

Author

Gil-Lespinard, Mercedes, Almanza-Aguilera, Enrique, Castañeda, Jazmín, Guiñón-Fort, Daniel, Eriksen, Anne Kirstine, Tjønneland, Anne, Rothwell, Joseph A., Shah, Sanam, Cadeau, Claire, Katzke, Verena, Johnson, Theron, Schulze, Matthias B., Oliverio, Andreina, Pasanisi, Fabrizio, Tumino, Rosario, Manfredi, Luca, Masala, Giovana, Skeie, Guri, Lundblad, Marie Wasmuth, Brustad, Magritt, Lasheras, Cristina, Crous-Bou, Marta, Molina-Montes, Esther, Colorado-Yohar, Sandra, Guevara, Marcela, Amiano, Pilar, Johansson, Ingegerd, Hultdin, Johan, Forouhi, Nita G., Freisling, Heinz, Merdas, Mira, Debras, Charlotte, Heath, Alicia K., Aglago, Elom K., Aune, Dagfinn, Zamora-Ros, Raul, Gil-Lespinard, Mercedes, Almanza-Aguilera, Enrique, Castañeda, Jazmín, Guiñón-Fort, Daniel, Eriksen, Anne Kirstine, Tjønneland, Anne, Rothwell, Joseph A., Shah, Sanam, Cadeau, Claire, Katzke, Verena, Johnson, Theron, Schulze, Matthias B., Oliverio, Andreina, Pasanisi, Fabrizio, Tumino, Rosario, Manfredi, Luca, Masala, Giovana, Skeie, Guri, Lundblad, Marie Wasmuth, Brustad, Magritt, Lasheras, Cristina, Crous-Bou, Marta, Molina-Montes, Esther, Colorado-Yohar, Sandra, Guevara, Marcela, Amiano, Pilar, Johansson, Ingegerd, Hultdin, Johan, Forouhi, Nita G., Freisling, Heinz, Merdas, Mira, Debras, Charlotte, Heath, Alicia K., Aglago, Elom K., Aune, Dagfinn, and Zamora-Ros, Raul

Abstract

Introduction: Dietary intake of (poly)phenols has been linked to reduced adiposity and body weight (BW) in several epidemiological studies. However, epidemiological evidence on (poly)phenol biomarkers, particularly plasma concentrations, is scarce. We aimed to investigate the associations between plasma (poly)phenols and prospective BW change in participants from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Methods: This study included 761 participants with data on BW at baseline and after 5 years of follow-up. Plasma concentrations of 36 (poly)phenols were measured at baseline using liquid chromatography-tandem mass spectrometry. Associations were assessed through general linear mixed models and multinomial logistic regression models, using change in BW as a continuous or as a categorical variable (BW loss, maintenance, gain), respectively. Plasma (poly)phenols were assessed as log2-transformed continuous variables. The false discovery rate (FDR) was used to control for multiple comparisons. Results: Doubling plasma (poly)phenol concentrations showed a borderline trend towards a positive association with BW loss. Plasma vanillic acid showed the strongest association (−0.53 kg/5 years; 95% confidence interval [CI]: −0.99, −0.07). Similar results were observed for plasma naringenin comparing BW loss versus BW maintenance (odds ratio: 1.1; 95% CI: 1.0, 1.2). These results did not remain significant after FDR correction. Conclusion: Higher concentrations of plasma (poly)phenols suggested a tendency towards 5-year BW maintenance or loss. While certain associations seemed promising, they did not withstand FDR correction, indicating the need for caution in interpreting these results. Further studies using (poly) phenol biomarkers are needed to confirm these suggestive protective trends.

Published
2024
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3. Healthy lifestyle and the risk of lymphoma in the EPIC study

Author

Naudin, Sabine, Solans Margalef, Marta, Saberi Hosnijeh, Fatemeh, Nieters, Alexandra, Kyrø, Cecilie, Tjønneland, Anne, Dahm, Christina C, Overvad, Kim, Mahamat‐saleh, Yahya, Besson, Caroline, Boutron‐Ruault, Marie‐Christine, Kühn, Tilman, Canzian, Federico, Schulze, Matthias B., Peppa, Eleni, Karakatsani, Anna, Trichopoulou, Antonia, Sieri, Sabina, Masala, Giovana, Panico, Salvatore, Tumino, Rosario, Ricceri, Fulvio, Chen, Sairah Lai Fa, Barroso, Leila Luján, Huerta, José María, Sánchez, Maria‐Jose, Ardanaz, Eva, Menéndez, Virginia, Amiano Exezarreta, Pilar, Spaeth, Florentin, Jerkeman, Mats, Jirstom, Karin, Schmidt, Julie A, Aune, Dagfinn, Weiderpass, Elisabete, Riboli, Elio, Vermeulen, Roel, Casabonne, Delphine, Gunter, Marc, Brennan, Paul, Ferrari, Pietro, IRAS OH Epidemiology Chemical Agents, and dIRAS RA-2

Subjects
immune system diseases, hemic and lymphatic diseases, non-Hodgkin lymphoma, healthy lifestyle index, EPIC, Hodgkin lymphoma, prospective study
Abstract

Limited evidence exists on the role of modifiable lifestyle factors on the risk of lymphoma. In this work, the associations between adherence to healthy lifestyles and risks of Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) were evaluated in a large-scale European prospective cohort. Within the European Prospective Investigation into Cancer and Nutrition (EPIC), 2,999 incident lymphoma cases (132 HL and 2,746 NHL) were diagnosed among 453,808 participants after 15 years (median) of follow-up. The healthy lifestyle index (HLI) score combined information on smoking, alcohol intake, diet, physical activity and BMI, with large values of HLI expressing adherence to healthy behavior. Cox proportional hazards models were used to estimate lymphoma hazard ratios (HR) and 95% confidence interval (CI). Sensitivity analyses were conducted by excluding, in turn, each lifestyle factor from the HLI score. The HLI was inversely associated with HL, with HR for a 1-standard deviation (SD) increment in the score equal to 0.78 (95%CI: 0.66, 0.94). Sensitivity analyses showed that the association was mainly driven by smoking and marginally by diet. NHL risk was not associated with the HLI, with HRs for a 1-SD increment equal to 0.99 (0.95, 1.03), with no evidence for heterogeneity in the association across NHL subtypes. In the EPIC study, adherence to healthy lifestyles was not associated with overall lymphoma or NHL risk, while an inverse association was observed for HL, although this was largely attributable to smoking. These findings suggest a limited role of lifestyle factors in the etiology of lymphoma subtypes. This article is protected by copyright. All rights reserved.

Published
2020

4. Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study

Author

Naudin, Sabine, primary, Solans Margalef, Marta, additional, Saberi Hosnijeh, Fatemeh, additional, Nieters, Alexandra, additional, Kyrø, Cecilie, additional, Tjønneland, Anne, additional, Dahm, Christina C., additional, Overvad, Kim, additional, Mahamat‐Saleh, Yahya, additional, Besson, Caroline, additional, Boutron‐Ruault, Marie‐Christine, additional, Kühn, Tilman, additional, Canzian, Federico, additional, Schulze, Matthias B., additional, Peppa, Eleni, additional, Karakatsani, Anna, additional, Trichopoulou, Antonia, additional, Sieri, Sabina, additional, Masala, Giovana, additional, Panico, Salvatore, additional, Tumino, Rosario, additional, Ricceri, Fulvio, additional, Chen, Sairah L.F., additional, Barroso, Leila L., additional, Huerta, José M., additional, Sánchez, Maria‐Jose, additional, Ardanaz, Eva, additional, Menéndez, Virginia, additional, Amiano Exezarreta, Pilar, additional, Spaeth, Florentin, additional, Jerkeman, Mats, additional, Jirstom, Karin, additional, Schmidt, Julie A., additional, Aune, Dagfinn, additional, Weiderpass, Elisabete, additional, Riboli, Elio, additional, Vermeulen, Roel, additional, Casabonne, Delphine, additional, Gunter, Marc, additional, Brennan, Paul, additional, and Ferrari, Pietro, additional

Published
2020
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5. Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study

Author

Naudin, Sabine, Margalef, Marta Solans, Hosnijeh, Fatemeh Saberi, Nieters, Alexandra, Kyrø, Cecilie, Tjønneland, Anne, Dahm, Christina C., Overvad, Kim, Mahamat-Saleh, Yahya, Besson, Caroline, Boutron-Ruault, Marie-Christine, Kühn, Tilman, Canzian, Federico, Schulze, Matthias B., Peppa, Eleni, Karakatsani, Anna, Trichopoulou, Antonia, Sieri, Sabina, Masala, Giovana, Panico, Salvatore, Tumino, Rosario, Ricceri, Fulvio, Chen, Sairah L. F., Barroso, Leila L., Huerta, José M., Sánchez, Maria-Jose, Ardanaz, Eva, Menendez, Virginia, Exezarreta, Pilar Amiano, Späth, Florentin, Jerkeman, Mats, Jirstom, Karin, Schmidt, Julie A., Aune, Dagfinn, Weiderpass, Elisabete, Riboli, Elio, Vermeulen, Roel, Casabonne, Delphine, Gunter, Marc, Brennan, Paul, Ferrari, Pietro, Naudin, Sabine, Margalef, Marta Solans, Hosnijeh, Fatemeh Saberi, Nieters, Alexandra, Kyrø, Cecilie, Tjønneland, Anne, Dahm, Christina C., Overvad, Kim, Mahamat-Saleh, Yahya, Besson, Caroline, Boutron-Ruault, Marie-Christine, Kühn, Tilman, Canzian, Federico, Schulze, Matthias B., Peppa, Eleni, Karakatsani, Anna, Trichopoulou, Antonia, Sieri, Sabina, Masala, Giovana, Panico, Salvatore, Tumino, Rosario, Ricceri, Fulvio, Chen, Sairah L. F., Barroso, Leila L., Huerta, José M., Sánchez, Maria-Jose, Ardanaz, Eva, Menendez, Virginia, Exezarreta, Pilar Amiano, Späth, Florentin, Jerkeman, Mats, Jirstom, Karin, Schmidt, Julie A., Aune, Dagfinn, Weiderpass, Elisabete, Riboli, Elio, Vermeulen, Roel, Casabonne, Delphine, Gunter, Marc, Brennan, Paul, and Ferrari, Pietro

Abstract

Limited evidence exists on the role of modifiable lifestyle factors on the risk of lymphoma. In this rk, the associations between adherence to healthy lifestyles and risks of Hodgkin lymphoma (HL) and n-Hodgkin lymphoma (NHL) were evaluated in a large-scale European prospective cohort. Within the ropean Prospective Investigation into Cancer and Nutrition (EPIC), 2,999 incident lymphoma cases 32 HL and 2,746 NHL) were diagnosed among 453,808 participants after 15 years (median) of follow- . The healthy lifestyle index (HLI) score combined information on smoking, alcohol intake, diet, ysical activity and BMI, with large values of HLI expressing adherence to healthy behavior. Cox oportional hazards models were used to estimate lymphoma hazard ratios (HR) and 95% confidence terval (CI). Sensitivity analyses were conducted by excluding, in turn, each lifestyle factor from the HLI ore. The HLI was inversely associated with HL, with HR for a 1-standard deviation (SD) increment in the ore equal to 0.78 (95% CI: 0.66, 0.94). Sensitivity analyses showed that the association was mainly iven by smoking and marginally by diet. NHL risk was not associated with the HLI, with HRs for a 1-SD crement equal to 0.99 (0.95, 1.03), with no evidence for heterogeneity in the association across NHL btypes. In the EPIC study, adherence to healthy lifestyles was not associated with overall lymphoma or NHL risk, while an inverse association was observed for HL, although this was largely attributable to smoking. These findings suggest a limited role of lifestyle factors in the etiology of lymphoma subtypes.

Published
2020
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6. Healthy lifestyle and the risk of lymphoma in the EPIC study

Author

IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Naudin, Sabine, Solans Margalef, Marta, Saberi Hosnijeh, Fatemeh, Nieters, Alexandra, Kyrø, Cecilie, Tjønneland, Anne, Dahm, Christina C, Overvad, Kim, Mahamat‐saleh, Yahya, Besson, Caroline, Boutron‐Ruault, Marie‐Christine, Kühn, Tilman, Canzian, Federico, Schulze, Matthias B., Peppa, Eleni, Karakatsani, Anna, Trichopoulou, Antonia, Sieri, Sabina, Masala, Giovana, Panico, Salvatore, Tumino, Rosario, Ricceri, Fulvio, Chen, Sairah Lai Fa, Barroso, Leila Luján, Huerta, José María, Sánchez, Maria‐Jose, Ardanaz, Eva, Menéndez, Virginia, Amiano Exezarreta, Pilar, Spaeth, Florentin, Jerkeman, Mats, Jirstom, Karin, Schmidt, Julie A, Aune, Dagfinn, Weiderpass, Elisabete, Riboli, Elio, Vermeulen, Roel, Casabonne, Delphine, Gunter, Marc, Brennan, Paul, Ferrari, Pietro, IRAS OH Epidemiology Chemical Agents, dIRAS RA-2, Naudin, Sabine, Solans Margalef, Marta, Saberi Hosnijeh, Fatemeh, Nieters, Alexandra, Kyrø, Cecilie, Tjønneland, Anne, Dahm, Christina C, Overvad, Kim, Mahamat‐saleh, Yahya, Besson, Caroline, Boutron‐Ruault, Marie‐Christine, Kühn, Tilman, Canzian, Federico, Schulze, Matthias B., Peppa, Eleni, Karakatsani, Anna, Trichopoulou, Antonia, Sieri, Sabina, Masala, Giovana, Panico, Salvatore, Tumino, Rosario, Ricceri, Fulvio, Chen, Sairah Lai Fa, Barroso, Leila Luján, Huerta, José María, Sánchez, Maria‐Jose, Ardanaz, Eva, Menéndez, Virginia, Amiano Exezarreta, Pilar, Spaeth, Florentin, Jerkeman, Mats, Jirstom, Karin, Schmidt, Julie A, Aune, Dagfinn, Weiderpass, Elisabete, Riboli, Elio, Vermeulen, Roel, Casabonne, Delphine, Gunter, Marc, Brennan, Paul, and Ferrari, Pietro

Published
2020

7. Healthy lifestyle and the risk of pancreatic cancer in the EPIC study

Author

MS MDL 1, Epidemiology & Health Economics, Cancer, JC onderzoeksprogramma Kanker, Epi Kanker Team A, Naudin, Sabine, Viallon, Vivian, Hashim, Dana, Freisling, Heinz, Jenab, Mazda, Weiderpass, Elisabete, Perrier, Flavie, McKenzie, Fiona, Bueno-de-Mesquita, H Bas, Olsen, Anja, Tjønneland, Anne, Dahm, Christina C, Overvad, Kim, Mancini, Francesca R, Rebours, Vinciane, Boutron-Ruault, Marie-Christine, Katzke, Verena, Kaaks, Rudolf, Bergmann, Manuela, Boeing, Heiner, Peppa, Eleni, Karakatsani, Anna, Trichopoulou, Antonia, Pala, Valeria, Masala, Giovana, Panico, Salvatore, Tumino, Rosario, Sacerdote, Carlotta, May, Anne M, van Gils, Carla H, Rylander, Charlotta, Borch, Kristin Benjaminsen, Chirlaque López, María Dolores, Sánchez, Maria-Jose, Ardanaz, Eva, Quirós, José Ramón, Amiano Exezarreta, Pilar, Sund, Malin, Drake, Isabel, Regnér, Sara, Travis, Ruth C, Wareham, Nick, Aune, Dagfinn, Riboli, Elio, Gunter, Marc J, Duell, Eric J, Brennan, Paul, Ferrari, Pietro, MS MDL 1, Epidemiology & Health Economics, Cancer, JC onderzoeksprogramma Kanker, Epi Kanker Team A, Naudin, Sabine, Viallon, Vivian, Hashim, Dana, Freisling, Heinz, Jenab, Mazda, Weiderpass, Elisabete, Perrier, Flavie, McKenzie, Fiona, Bueno-de-Mesquita, H Bas, Olsen, Anja, Tjønneland, Anne, Dahm, Christina C, Overvad, Kim, Mancini, Francesca R, Rebours, Vinciane, Boutron-Ruault, Marie-Christine, Katzke, Verena, Kaaks, Rudolf, Bergmann, Manuela, Boeing, Heiner, Peppa, Eleni, Karakatsani, Anna, Trichopoulou, Antonia, Pala, Valeria, Masala, Giovana, Panico, Salvatore, Tumino, Rosario, Sacerdote, Carlotta, May, Anne M, van Gils, Carla H, Rylander, Charlotta, Borch, Kristin Benjaminsen, Chirlaque López, María Dolores, Sánchez, Maria-Jose, Ardanaz, Eva, Quirós, José Ramón, Amiano Exezarreta, Pilar, Sund, Malin, Drake, Isabel, Regnér, Sara, Travis, Ruth C, Wareham, Nick, Aune, Dagfinn, Riboli, Elio, Gunter, Marc J, Duell, Eric J, Brennan, Paul, and Ferrari, Pietro

Published
2020

8. Healthy lifestyle and the risk of pancreatic cancer in the EPIC study

Author

Naudin, Sabine, primary, Viallon, Vivian, additional, Hashim, Dana, additional, Freisling, Heinz, additional, Jenab, Mazda, additional, Weiderpass, Elisabete, additional, Perrier, Flavie, additional, McKenzie, Fiona, additional, Bueno-de-Mesquita, H Bas, additional, Olsen, Anja, additional, Tjønneland, Anne, additional, Dahm, Christina C., additional, Overvad, Kim, additional, Mancini, Francesca R., additional, Rebours, Vinciane, additional, Boutron-Ruault, Marie-Christine, additional, Katzke, Verena, additional, Kaaks, Rudolf, additional, Bergmann, Manuela, additional, Boeing, Heiner, additional, Peppa, Eleni, additional, Karakatsani, Anna, additional, Trichopoulou, Antonia, additional, Pala, Valeria, additional, Masala, Giovana, additional, Panico, Salvatore, additional, Tumino, Rosario, additional, Sacerdote, Carlotta, additional, May, Anne M., additional, van Gils, Carla H., additional, Rylander, Charlotta, additional, Borch, Kristin Benjaminsen, additional, Chirlaque López, María Dolores, additional, Sánchez, Maria-Jose, additional, Ardanaz, Eva, additional, Quirós, José Ramón, additional, Amiano Exezarreta, Pilar, additional, Sund, Malin, additional, Drake, Isabel, additional, Regnér, Sara, additional, Travis, Ruth C., additional, Wareham, Nick, additional, Aune, Dagfinn, additional, Riboli, Elio, additional, Gunter, Marc J., additional, Duell, Eric J., additional, Brennan, Paul, additional, and Ferrari, Pietro, additional

Published
2019
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