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484 results on '"Marumo, K."'

1. Fractal Properties in Economics

Author

Takayasu, H., Takayasu, M., Okazaki, M. P., Marumo, K., and Shimizu, T.

Subjects
Condensed Matter - Statistical Mechanics, Quantitative Finance - General Finance, Quantitative Finance - Statistical Finance
Abstract

Scaling properties in financial fluctuations are reviewed from the standpoint of statistical physics. We firstly show theoretically that the balance of demand and supply enhances fluctuations due to the underlying phase transition mechanism. By analyzing tick data of yen-dollar exchange rates we confirm two fractal properties: 1 The distribution of rate change in a fixed ticks is approximated by a symmetric stretched exponential function for a wide range of time intervals; 2 the interval time distribution of trades nearly follows a power law. Empirical fractal properties in companies' financial data, such as distributions and fluctuations in assets and incomes are discussed with a simple model. The importance of methods and theories for phase transitions is discussed., Comment: 15 pages, 10 figures http://www.hi-ho.ne.jp/f6586719/ecph/index.html in 'Paradigms of Complexity', World Scientific, ed. Miroslav M. Novak, (2000)(ISBN 981-02-4292-1), pp.243-258

Published
2000

27. The effect of magmatic activity on hydrothermal venting along the superfast-spreading East Pacific Rise

Author

Urabe, T., Baker, E.T., Ishibashi, J., Feely, R.A., Marumo, K., Massoth, G.J., Maruyama, A., Shitashima, K., Okamura, K., Lupton, J.E., Sonoda, A., Yamazaki, T., Aoki, M., Gendron, J., Greene, R., Kaiho, Y., Kisimoto, K., Lebon, G., Matsumoto, T., Nakamura, K., Nishizawa, A., Okano, O., Paradis, G., Roe, K., Shibata, T., Tennant, D., Vance, T., Walker, S.L., Yabuki, T., and Ytow, N.

Subjects
East Pacific Rise -- Research, Hydrothermal vents -- Research, Sea-floor spreading -- Research, Science and technology, Research
Abstract

A survey of hydrothermal activity along the superfast-spreading (approximately 150 millimeters per year) East Pacific Rise shows that hydrothermal plumes overlay approximately 60 percent of the ridge crest between 13°50' and 18°40'S, a plume abundance nearly twice that known from any other ridge portion of comparable length. Plumes were most abundant where the axial cross section is inflated and an axial magma chamber is present. Plumes with high ratios of volatile (³He, [CH.sub.4], and [H.sub.2]S) to nonvolatile (Mn and Fe) species marked where hydrothermal circulation has been perturbed by recent magmatic activity. The high proportion of volatile-rich plumes observed implies that such episodes are more frequent here than on slower spreading ridges., The circulation of seawater through the geothermally heated rocks of oceanic spreading ridges is the principal agent for the transfer of energy and mass between the oceanic crust and its [...]

Published
1995

32. Postersitzung 7: Urologische Tumoren — Grundlagenforschung

Author

Miersch, W.-D., Rübben, H., Deutz, F. J., Enger, S., Recker, F., Tanke, H. J., de Goey, R., Jonas, U., Stöckle, M., Mlynek, M.-L., Cevc, G., Hartung, R., Kropp, W., Rammal, E., Feichtinger, J., Jakse, G., Mack, D., Günther, M., Schubert, G. E., Bussemakers, M. J. G., Schalken, J. A., Kurth, K. H., Feitz, W. F. J., Debruyne, F. M. J., Bloemers, H. P. J., Van de Ven, W. J. M., Karthaus, H. F. M., Mallmann, P., Brühl, P., Hermanns, M., Tachibana, M., Tazaki, H., Nakamura, S., Wolf, G., Scherberich, J. E., Karich, H., Fischer, P., Schoeppe, W., Jonas, D., Hanke, P., Huland, H., Klosterhalfen, H., Otto, U., Schneider, A. W., Baisch, H., Klöppel, G., Hammerer, P., van Moorselaar, R. J. A., Peelen, W. P., Hendriks, B. Th., Beniers, A. J. M. C., Naito, S., Fidler, I. J., Heicappell, R., Marumo, K., Baba, S., Deguchi, N., Rassweiler, J., Roeren, Th., Kauffmann, G. W., Richter, G. M., Schmitz-Dräger, B. J., Rohde, D., Peschkes, C., Ackermann, R., Valet, G., Lehmer, A., Kahle, H., Leyh, H., and Ackermann, Rolf, editor

Published
1988
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37. DS02R1

Author

Cullings, H.M., primary, Grant, E.J., additional, Egbert, S.D., additional, Watanabe, T., additional, Oda, T., additional, Nakamura, F., additional, Yamashita, T., additional, Fuchi, H., additional, Funamoto, S., additional, Marumo, K., additional, Sakata, R., additional, Kodama, Y., additional, Ozasa, K., additional, and Kodama, K., additional

Published
2017
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41. Treatment with eldecalcitol positively affects mineralization, microdamage, and collagen crosslinks in primate bone

Author

Saito, M., Grynpas, MD., Burr, DB., Allen, MR., Smith, SY., Doyle, N., 1000030242431, Amizuka, N., 1000050739349, Hasegawa, T., Kida, Y., Marumo, K., Saito H., Saito, M., Grynpas, MD., Burr, DB., Allen, MR., Smith, SY., Doyle, N., 1000030242431, Amizuka, N., 1000050739349, Hasegawa, T., Kida, Y., Marumo, K., and Saito H.

Abstract

Eldecalcitol (ELD), an active form of vitamin D analog approved for the treatment of osteoporosis in Japan, increases lumbar spine bone mineral density (BMD), suppresses bone turnover markers, and reduces fracture risk in patients with osteoporosis.We have previously reported that treatmentwith ELD for 6months improved the mechanical properties of the lumbar spine in ovariectomized (OVX) cynomolgus monkeys. ELD treatment increased lumbar BMD, suppressed bone turnover markers, and reduced histomorphometric parameters of both bone formation and resorption in vertebral trabecular bone. In this study, we elucidated the effects of ELD on bone quality (namely, mineralization, microarchitecture, microdamage, and bone collagen crosslinks) in OVX cynomolgus monkeys in comparison with OVX-vehicle control monkeys. Density fractionation of bone powder prepared from lumbar vertebrae revealed that ELD treatment shifted the distribution profile of bone mineralization to a higher density, and backscattered electronmicroscopic imaging showed improved trabecular bone connectivity in the ELD-treated groups. Higher doses of ELD more significantly reduced the amount of microdamage compared to OVX-vehicle controls. The fractionated bone powder sampleswere divided according to their density, and analyzed for collagen crosslinks. Enzymatic crosslinks were higher in both the high-density (?2.0 mg/mL) and low-density (b2.0 mg/mL) fractions from the ELD-treated groups than in the corresponding fractions in the OVX-vehicle control groups. On the other hand, non-enzymatic crosslinkswere lower in both the high- and low-density fractions. These observations indicated that ELD treatment stimulated the enzymatic reaction of collagen crosslinks and bonemineralization, but prevented non-enzymatic reaction of collagen crosslinks and accumulation of bone microdamage. Bone anti-resorptive agents such as bisphosphonates slow down bone remodeling so that bone mineralization, bonemicrodamage, and non-enzym

Published
2015

42. Prevalence of renal cell carcinoma: a nation-wide survey in Japan, 2002

Author

Marumo, K, Kanayama, H, Miyao, N, Nakazawa, H, Ozono, S, Horie, S, Nagamori, S, Igarashi, T, Hasegawa, M, Kimura, G, Nakao, M, Nakamoto, T, and Naito, S

Subjects
Male, Japan, Data Collection, Incidence, Prevalence, Humans, Female, Registries, Carcinoma, Renal Cell, Kidney Neoplasms
Abstract

To investigate the incidence of renal cell carcinoma, classified by sex, age group and region in Japan, following a 5-year interval after a previous survey performed in 1997.The survey was conducted between the beginning of January 2002 and the end of December 2002. A total of 1288 institutions in all 47 prefectures throughout Japan were requested to register cases.There were 7405 persons with renal cell carcinoma, consisting of 5063 males and 2342 females. Crude incidence rates were 8.2 and 3.6 per 100 000 population for men and women, respectively. Incidence rates in the Hokkaido region were highest followed by the Shikoku region.Despite incidence of renal cell carcinoma increasing to 7405 from the 6358 persons in 1997, statistical data reported by the Ministry of Health, Labor and Welfare indicate that rising age-adjusted death rate for this tumor reached a ceiling in the past decade. Early detection may have contributed to this current trend; however, further epidemiological research is required to fully elucidate this.

Published
2007

44. A comparison of the efficacy and tolerability of tadalafil 10 mg and 20 mg in Japanese patients with severe erectile dysfunction

Author

Marumo, K, Imaoka, T, Fujimoto, K, Watts, S, Stothard, D, and McGill, J

Subjects
Adult, Male, Dose-Response Relationship, Drug, Phosphodiesterase Inhibitors, Penile Erection, Vasodilator Agents, Middle Aged, Severity of Illness Index, Drug Administration Schedule, Tadalafil, Treatment Outcome, Double-Blind Method, Erectile Dysfunction, Japan, Patient Satisfaction, Research Design, Humans, Carbolines
Abstract

Tadalafil is a phosphodiesterase type 5 inhibitor with documented efficacy in the treatment of erectile dysfunction (ED).To compare the efficacy and tolerability of tadalafil 10 mg and 20 mg in men with severe ED.A prespecified subgroup analysis was conducted to compare the efficacy of tadalafil 10 and 20 mg measured by the International Index of Erectile Function (IIEF) erectile function (EF) domain and Sexual Encounter Profile (SEP) among patients with severe ED (EF domain score = 1-10) in a Japanese placebo-controlled study (PCT). We also analyzed the efficacy of the two doses in men with severe ED post hoc by pooling data from three tadalafil clinical trials that evaluated these doses using a similar study design (three placebo-controlled trials), and evaluated (post hoc) the presence of organic comorbidities in patients with different levels of response to tadalafil 10 or 20 mg.Mean change in the IIEF-EF domain and mean per-patient changes in percent "yes" responses to SEP Question 2 (SEP2) and Question 3 (SEP3).Patients with severe ED in the Japanese study experienced numerically greater increases (improvements) when taking tadalafil 20 mg compared with 10 mg in the IIEF-EF domain (14.3 vs. 12.4; P = 0.355), SEP2 (60% vs. 57%; P = 0.781), and SEP3 (61% vs. 49%, P = 0.196). When sufficiently powered, these observations reached statistical significance in the three PCTs: patients with severe ED experienced greater increases when taking tadalafil 20 mg compared with 10 mg in the IIEF-EF domain (13.6 vs. 10.4; P = 0.014) and SEP3 (56% vs. 43%, P = 0.019). Both doses were well tolerated.Patients with severe ED, and especially those with an organic comorbidity, may derive greater clinical benefits from tadalafil 20 mg compared with 10 mg.

Published
2006

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